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621 results on '"Zhang, Yuhu"'

103. β-decay study of neutron-rich nucleus 34Al

Author

Han, Rui, Li, XiangQing, Jiang, WeiGuang, Li, ZhiHuan, Hua, Hui, Zhang, ShuangQuan, Yuan, CenXi, Jiang, DongXing, Ye, YanLin, Li, Jing, Li, ZongHao, Xu, FuRong, Chen, QiBo, Meng, Jie, Wang, JianSong, Xu, Chuan, Sun, YeLei, Wang, ChunGuang, Wu, HongYi, Niu, ChenYang, Li, ChenGuang, He, Chao, Jiang, Wei, Li, PengJie, Zang, HongLiang, Feng, Jun, Chen, SiDong, Liu, Qiang, Chen, XiaoChi, Xu, HuShan, Hu, ZhengGuo, Yang, YanYun, Ma, Peng, Ma, JunBing, Jin, ShiLun, Bai, Zhen, Huang, MeiRong, Zhou, YuanJie, Ma, WeiHu, Li, Yong, Zhou, XiaoHong, Zhang, YuHu, Xiao, GuoQing, and Zhan, WenLong

Published
2017
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105. Lipid storage myopathy due to late-onset multiple Acyl-CoA dehydrogenase deficiency with novel mutations in ETFDH: A case report

Author

Tian, Huihong, Zhong, Yi, Liu, Zhihua, Wei, Liping, Yuan, Yanbo, Zhang, Yuhu, and Wang, Limin

Subjects
Neurology, Neurology (clinical)
Abstract

BackgroundLipid storage myopathy (LSM) is an autosomal recessive inherited lipid and amino metabolic disorder with great clinical heterogeneity. Variations in the electron transfer flavoprotein dehydrogenase (ETFDH) gene cause multiple acyl-CoA dehydrogenase deficiency (MADD), and have a manifestation of LSM. Muscle biopsy helps clarify the diagnosis of LSM, and next-generation sequencing (NGS) can be useful in identifying genomic mutation sites. The diagnosis of MADD contributes to targeted therapy.Case presentationWe report on a teenager who appeared to have muscle weakness and exercise intolerance at the onset. Before the referral to our hospital, he was unsuccessfully treated with glucocorticoid for suspected polymyositis. The next-generation sequencing of the proband and his parents revealed heterozygous variations, c.365G>A (p.G122D) inherited from the father, c.176-194_176-193del, and c.832-316C>T inherited from the mother in the ETFDH gene. The tandem mass spectrometry identified the mutations to be pathogenic. However, his parents and his younger sister who were detected with a mutation of c.365G>A presented no clinical symptoms. This indicates that the combination of the three compound heterozygous mutations in ETFDH is significant. After MADD was diagnosed, a dramatic clinical recovery and biochemical improvement presented as riboflavin was given to the patient across a week, which further confirmed the diagnosis of MADD.ConclusionOur observations extend the spectrum of ETFDH variants in Chinese the population and reinforce the role of NGS in diagnosis of MADD. Early diagnosis and appropriate treatment of LSM lead to great clinical efficacy and avoid some lethal complications.

Published
2022
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106. Endothelial LRP1-ICD Accelerates Cognition-Associated Alpha-Synuclein Pathology and Neurodegeneration through PARP1 Activation in a Mouse Model of Parkinson’s Disease

Author

Huang, Rui, primary, Gao, Yuyuan, additional, Duan, Qingrui, additional, Zhang, Qingxi, additional, He, Peikun, additional, Chen, Jianing, additional, Ma, Guixian, additional, Wang, Limin, additional, Zhang, Yuhu, additional, Nie, Kun, additional, and Wang, Lijuan, additional

Published
2022
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110. Distinct Bile Acid Signature in Parkinson's Disease With Mild Cognitive Impairment

Author

Nie, Kun, Li, Yanyi, Zhang, Jiahui, Gao, Yuyuan, Qiu, Yihui, Gan, Rong, Zhang, Yuhu, and Wang, Lijuan

Subjects
Neurology, Neurology (clinical)
Abstract

BackgroundsBile acid (BA) plays a crucial role in various neurodegenerative diseases, including Parkinson's disease (PD). However, no clinical evidence supports BA's potential role in patients with PD with mild cognitive impairment (PD-MCI).ObjectivesThis study aimed at investigating the differential BA profile between patients with PD-MCI and those with normal cognitive function (PD-NC).MethodsUltra-high performance liquid chromatography-MS/MS was applied for BA quantitation. After between-group differences of the BA profile were addressed, orthogonal projections to latent structures—discriminant analysis (OPLS-DA) and the area under the receiver-operating-characteristic curve (AUC-ROC) were implemented for further verification.ResultsLower levels of chenodeoxycholic acid (CDCA), cholic acid (CA), and ursodeoxycholic acid (UDCA) were significantly associated with PD-MCI (p < 0.01 for both; VIP ≈ 2.67, 1.66, and 1.26, respectively). AUC-ROC were 78.1, 74.2, and 74.5% for CDCA, CA, and UDCA, respectively.ConclusionCA, CDCA, and UDCA might be distinct BA signatures for patients with PD-MCI.

Published
2022
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119. TGR5 Agonist INT-777 Alleviates Inflammatory Neurodegeneration in Parkinson’s Disease Mouse Model by Modulating Mitochondrial Dynamics in Microglia

Author

Huang, Rui, primary, Gao, Yuyuan, additional, Chen, Jianing, additional, Duan, Qingrui, additional, He, Peikun, additional, Zhang, Jiahui, additional, Huang, Heling, additional, Zhang, Qingxi, additional, Ma, Guixian, additional, Zhang, Yuhu, additional, Nie, Kun, additional, and Wang, Lijuan, additional

Published
2022
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122. Diffusion along perivascular spaces provides evidence interlinking compromised glymphatic function with aging in Parkinson's disease.

Author

Cai, Xin, Chen, Zhenzhen, He, Chentao, Zhang, Piao, Nie, Kun, Qiu, Yihui, Wang, Limin, Wang, Lijuan, Jing, Ping, and Zhang, Yuhu

Subjects
PARKINSON'S disease, DIFFUSION tensor imaging, IMAGE analysis, CALCULUS of tensors, SLEEP disorders
Abstract

Aims: The aim of the study was to evaluate the glymphatic function and its related factors in patients with Parkinson's disease (PD) and patients with PD of different ages using the diffusion tensor image analysis along the perivascular space (DTI‐ALPS) method. Methods: Medical records and imaging data of 93 patients with idiopathic PD and 42 age‐ and sex‐matched healthy controls (HCs) were retrospectively reviewed and analyzed. The diffusivity along the perivascular spaces, projection fibers, and association fibers were calculated on diffusion tensor imaging (DTI) to acquire the analysis along the perivascular space (ALPS) index. Results: PD patients exhibited a reduced ALPS index compared with the HCs. Negative correlations between the ALPS index and clinical information including age, age at disease onset, Parkinson's disease sleep scale 2nd version (PDSS‐2) scores, and history of diabetes mellitus were revealed in the PD group. Besides, a negative correlation between the ALPS index and the severity of motor symptoms was identified in the subgroup aged 65 and above, rather than in the younger ones. Conclusions: The results demonstrate that reduced ALPS index, a potential noninvasive measure of compromised glymphatic activity, is involved in the pathophysiology of PD, especially in the aged ones and those with sleep disorders. [ABSTRACT FROM AUTHOR]

Published
2023
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123. β-Delayed γ Emissions of 26P and Its Mirror Asymmetry

Author

Jian, Hao, primary, Gao, Yufeng, additional, Dai, Fanchao, additional, Liu, Jiajian, additional, Xu, Xinxing, additional, Yuan, Cenxi, additional, Kaneko, Kazunari, additional, Sun, Yang, additional, Liang, Pengfei, additional, Shi, Guozhu, additional, Sun, Lijie, additional, Xayavong, Latsamy, additional, Lin, Chengjian, additional, Lee, Jenny, additional, Li, Zhihuan, additional, Yang, Yanyun, additional, Li, Pengjie, additional, Fan, Rui, additional, Zha, Sixian, additional, Zhu, Haofan, additional, Li, Jinhai, additional, Gao, Qirui, additional, Zhang, Zhaozhan, additional, Chen, Ruofu, additional, Wang, Jiansong, additional, Wang, Dongxi, additional, Wu, Hongyi, additional, Wang, Kang, additional, Lam, Yihua, additional, Duan, Fangfang, additional, Ma, Peng, additional, Gao, Zhihao, additional, Hu, Qiang, additional, Bai, Zhen, additional, Ma, Junbing, additional, Wang, Jianguo, additional, Zhong, Fupeng, additional, Wu, Chenguang, additional, Luo, Diwen, additional, Jiang, Ying, additional, Liu, Yang, additional, Hou, Dongsheng, additional, Li, Ren, additional, Ma, Nanru, additional, Ma, Weihu, additional, Yu, Gongming, additional, Patel, Dipika, additional, Jin, Shuya, additional, Wang, Yufeng, additional, Yu, Yuechao, additional, Zhou, Qingwu, additional, Wang, Peng, additional, Hu, Liyuan, additional, Wang, Xiang, additional, Zang, Hongliang, additional, Zhao, Qingqing, additional, Yang, Lei, additional, Wen, Peiwei, additional, Yang, Feng, additional, Jia, Huiming, additional, Zhang, Gaolong, additional, Pan, Min, additional, Wang, Xiaoyu, additional, Sun, Haohan, additional, Wang, Meng, additional, Hu, Zhengguo, additional, Zhou, Xiaohong, additional, Zhang, Yuhu, additional, Xu, Hushan, additional, Liu, Minliang, additional, Ong, Hooi-Jin, additional, and Yang, Weiqing, additional

Published
2021
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128. Correction to: Identifying Parkinson’s disease with mild cognitive impairment by using combined MR imaging and electroencephalogram

Author

Zhang, Jiahui, primary, Gao, Yuyuan, additional, He, Xuetao, additional, Feng, Shujun, additional, Hu, Jinlong, additional, Zhang, Qingxi, additional, Zhao, Jiehao, additional, Huang, Zhiheng, additional, Wang, Limin, additional, Ma, Guixian, additional, Zhang, Yuhu, additional, Nie, Kun, additional, and Wang, Lijuan, additional

Published
2021
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133. Study of proton resonances in 18Ne via resonant elastic scattering of 17F+p and its astrophysical implication

Author

He, JianJun, Hu, Jun, Xu, ShiWei, Chen, ZhiQiang, Zhang, XueYing, Wang, JianSong, Yu, XiangQing, Zhang, LiYong, Li, Long, Yang, YanYun, Ma, Peng, Zhang, XueHeng, Hu, ZhengGuo, Guo, ZhongYan, Xu, Xing, Yuan, XiaoHua, Lu, Wan, Yu, YuHong, Zang, YongDong, Tang, ShuWen, Ye, RuiPing, Chen, JinDa, Jin, ShiLun, Du, ChengMing, Wang, ShiTao, Ma, JunBing, Liu, LongXiang, Bai, Zhen, Lei, XiangGuo, Sun, ZhiYu, Zhang, YuHu, Zhou, XiaoHong, Xu, HuShan, Su, Jun, Li, ErTao, Wang, HongWei, Tian, WenDong, and Li, XiangQing

Published
2011
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134. First mass measurement of short-lived nuclides at HIRFL-CSR

Author

Xu, HuShan, Tu, XiaoLin, Yuan, YouJin, Xia, JiaWen, Zang, YongDong, Wang, Meng, Mao, RuiShi, Hu, ZhengGuo, Mei, Bo, Shuai, Peng, Zhu, ZhiChao, Tang, ShuWen, Geng, Peng, Liu, Yong, Zhao, TieCheng, Zhang, XueYing, Yang, JianCheng, Mao, LiJun, Zhang, YuHu, Zhou, XiaoHong, Huang, WenXue, Xiao, GuoQing, Zhao, HongWei, and Zhan, WenLong

Published
2009
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135. High-spin structure in 187Pt

Author

Xing, YeBing, Zhou, XiaoHong, Zhang, YuHu, Guo, YingXiang, Ma, Long, Lei, XiangGuo, Guo, WenTao, Oshima, M., Toh, Y., Koizumi, M., Osa, A., Hatsukawa, Y., Xu, FuRong, and Sugawara, M.

Published
2008
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136. Measurement of the Transition Energy \(\gamma _{t}\) and Isochronicity Correction in the CSRe Storage Ring

Author

Ge, Wen Wen, primary, Chen, Rui Jiu, additional, Yan, Xin Liang, additional, Yuan, You Jin, additional, Wang, Meng, additional, Sun, Ming Ze, additional, Xing, Yuan Ming, additional, Zhang, Peng, additional, Fu, Chao Yi, additional, Shuai, Peng, additional, Xu, Xing, additional, Zhang, Yuhu, additional, Bao, Tong, additional, Chen, Xiang Cheng, additional, Hu, Xue Jing, additional, Huang, Wen Jia, additional, Li, Hong Fu, additional, Liu, Jun Hao, additional, Litvinov, Yuri A., additional, Litvinov, Sergey, additional, Mao, Li Jun, additional, Wu, Bo, additional, Xu, Hu Shan, additional, Yang, Jian Cheng, additional, Yin, Da Yu, additional, Zeng, Qi, additional, Zhang, Xiao Hu, additional, Zheng, Wen Heng, additional, Zhou, Xiao Hong, additional, and Zhou, Xu, additional

Published
2021
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140. A Novel NIR–Red Spectral Domain Evapotranspiration Model From the Chinese GF-1 Satellite: Application to the Huailai Agricultural Region of China

Author

Yao, Yunjun, primary, Liang, Shunlin, additional, Fisher, Joshua B., additional, Zhang, Yuhu, additional, Cheng, Jie, additional, Chen, Jiquan, additional, Jia, Kun, additional, Zhang, Xiaotong, additional, Bei, Xiangyi, additional, Shang, Ke, additional, Guo, Xiaozheng, additional, and Yang, Junming, additional

Published
2021
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142. Measurement of the 52Fe mass via the precise proton-decay energy of 53Com

Author

Shen Yangping, Liu Weiping, Su Jun, Zhang Ningtao, Jing Long, Li Zhihong, Wang Youbao, Guo Bing, Yan Shengquan, Li Yunju, Zeng Sheng, Lian Gang, Du Xianchao, Gan Lin, Bai Xixiang, Wang Jiansong, Zhang Yuhu, Zhou Xiaohong, Tang Xiaodong, He Jianjun, Yang Yanyun, Jin Shilun, Ma Peng, Ma Junbing, Huang Meirong, Bai Zhen, Zhou Yuanjie, Ma Weihu, Hu Jun, Xu Shiwei, Ma Shaobo, Chen Size, Zhang Liyong, Ding Bing, and Li Zhihuan

Subjects
Physics, QC1-999
Abstract

The proton decay of 53Com(3174.1 keV; 19/2−) was investigated via the fragmentation of a 58Ni primary beam. The proton-decay energy was determined with an improved precision to be 1558(8) keV. With this new result and the mass of 53Com, the 52Fe mass excess was derived to be −48330(8) keV, which is in good agreement with the AME12 value. A new recommended value of −48331.6(49) keV is given.

Published
2016
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143. Global Socioeconomic Risk of Precipitation Extremes Under Climate Change

Author

Quansheng Ge, Yanhua Liu, Philippe Ciais, Tao Pan, Yujie Liu, Jie Chen, Josep Peñuelas, Zhang Yuhu, Chinese Academy of Sciences [Beijing] (CAS), Laboratoire des Sciences du Climat et de l'Environnement [Gif-sur-Yvette] (LSCE), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), ICOS-ATC (ICOS-ATC), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), CREAF - Centre for Ecological Research and Applied Forestries, Institut national des sciences de l'Univers (INSU - CNRS)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Versailles Saint-Quentin-en-Yvelines (UVSQ), and Institut national des sciences de l'Univers (INSU - CNRS)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)

Subjects
010504 meteorology & atmospheric sciences, 02 engineering and technology, 01 natural sciences, Gross domestic product, Volcanic Hazards and Risks, Earth and Planetary Sciences (miscellaneous), Climate change, RCP scenarios, Disaster Risk Analysis and Assessment, 020701 environmental engineering, Research Articles, lcsh:Environmental sciences, General Environmental Science, media_common, [SDU.OCEAN]Sciences of the Universe [physics]/Ocean, Atmosphere, lcsh:GE1-350, education.field_of_study, 1. No poverty, Representative Concentration Pathways, Climate Impact, Geography, Purchasing power parity, climate change, Impacts of Global Change, Mathematical Geophysics, Research Article, Persistence, Memory, Correlations, Clustering, precipitation extremes, Inequality, media_common.quotation_subject, Population, 0207 environmental engineering, Volcanology, Socioeconomic risk, Exposure, Extreme Events, lcsh:QH540-549.5, Economic Impacts of Disasters, Global Change, Precipitation, [SDU.ENVI]Sciences of the Universe [physics]/Continental interfaces, environment, education, Socioeconomic status, 0105 earth and related environmental sciences, Policy Sciences, Climate Impacts, SSP scenarios, Benefit‐cost Analysis, socioeconomic risk, 13. Climate action, Volcano/Climate Interactions, Regional Climate Change, Physical geography, Precipitation extremes, lcsh:Ecology, Hydrology, Natural Hazards
Abstract

Precipitation extremes are among the most serious consequences of climate change around the world. The observed and projected frequency and intensity of extreme precipitation in some regions will greatly influence the social economy. The frequency of extreme precipitation and the population and economic exposure were quantified for a base period (1986–2005) and future periods (2016–2035 and 2046–2065) based on bias corrected projections of daily precipitation from five global climatic models forced with three representative concentration pathways (RCPs) and projections of population and gross domestic product (GDP) in the shared socioeconomic pathways (SSPs). The RCP8.5‐SSP3 scenario produces the highest global population exposure for 2046–2065, with nearly 30% of the global population (2.97 × 109 persons) exposed to precipitation extremes >10 days/a. The RCP2.6‐SSP1 scenario produces the highest global GDP exposure for 2046–2065, with a 5.56‐fold increase relative to the base period, of up to (2.29 ± 0.20) × 1015 purchasing power parity $‐days. Socioeconomic effects are the primary contributor to the exposure changes at the global and continental scales. Population and GDP effects account for 64–77% and 78–91% of the total exposure change, respectively. The inequality of exposure indicates that more attention should be given to Asia and Africa due to their rapid increases in population and GDP. However, due to their dense populations and high GDPs, European countries, that is, Luxembourg, Belgium, and the Netherlands, should also commit to effective adaptation measures., Key Points Global population and GDP exposures are highest for 2046–2065 in RCP8.5‐SSP3 and RCP2.6‐SSP1, 8.46 × 1010 person‐days and 2.29 × 1015PPP $‐daysIncreases in population and GDP are the dominant contributors, accounting for over 60% of future changes in socioeconomic exposureEffective adaptation is urgently needed for some European countries, for example, Luxembourg, the Netherlands, and Belgium, and in Asia and Africa

Published
2020
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149. Multi-quasiparticle excitations in145Tb

Author

Zheng, Yong, Zhou, Xiaohong, Zhang, Yuhu, Liu, Minliang, Guo, Yingxiang, Lei, Xiangguo, Hayakawa, T., Oshima, M., Toh, T., Shizuma, T., Katakura, J., Hatsukawa, Y., Matsuda, M., Kusakari, H., and Sugawara, M.

Published
2004
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150. High-spin states and signature inversion in odd-odd182Au

Author

Zhang, Yuhu, Xu, Furong, He, Jianjun, Liu, Zhong, Zhou, Xiaohong, Gan, Zaiguo, Oshima, M., Hayakawa, T., Toh, Y., Shizuma, T., Katakura, J., Hatsukawa, Y., Matsuda, M., Kusakari, H., Sugawara, M., Furuno, K., Komatsubara, T., Une, T., Wen, Shuxian, and Wang, Zhimin

Published
2003
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