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101. Optimization of the JUNO liquid scintillator composition using a Daya Bay antineutrino detector

Author

Bay, Daya, collaborations, JUNO, Abusleme, A., Adam, T., Ahmad, S., Aiello, S., Akram, M., Ali, N., An, F. P., An, G. P., An, Q., Andronico, G., Anfimov, N., Antonelli, V., Antoshkina, T., Asavapibhop, B., de André, J. P. A. M., Babic, A., Balantekin, A. B., Baldini, W., Baldoncini, M., Band, H. R., Barresi, A., Baussan, E., Bellato, M., Bernieri, E., Biare, D., Birkenfeld, T., Bishai, M., Blin, S., Blum, D., Blyth, S., Bordereau, C., Brigatti, A., Brugnera, R., Budano, A., Burgbacher, P., Buscemi, M., Bussino, S., Busto, J., Butorov, I., Cabrera, A., Cai, H., Cai, X., Cai, Y. K., Cai, Z. Y., Cammi, A., Campeny, A., Cao, C. Y., Cao, G. F., Cao, J., Caruso, R., Cerna, C., Chakaberia, I., Chang, J. F., Chang, Y., Chen, H. S., Chen, P. A., Chen, P. P., Chen, S. M., Chen, S. J., Chen, X. R., Chen, Y. W., Chen, Y. X., Chen, Y., Chen, Z., Cheng, J., Cheng, Y. P., Cheng, Z. K., Chepurnov, A., Cherwinka, J. J., Chiarello, F., Chiesa, D., Chimenti, P., Chu, M. C., Chukanov, A., Chuvashova, A., Clementi, ., Clerbaux, B., Di Lorenzo, S. Conforti, Corti, D., Costa, S., Corso, F. D., Cummings, J. P., Dalager, O., De La Taille, C., Deng, F. S., Deng, J. W., Deng, Z., Deng, Z. Y., Depnering, W., Diaz, M., Ding, X. F., Ding, Y. Y., Dirgantara, B., Dmitrievsky, S., Diwan, M. V., Dohnal, T., Donchenko, G., Dong, J. M., Dornic, D., Doroshkevich, E., Dove, J., Dracos, M., Druillole, F., Du, S. X., Dusini, S., Dvorak, M., Dwyer, D. A., Enqvist, T., Enzmann, H., Fabbri, A., Fajt, L., Fan, D. H., Fan, L., Fang, C., Fang, J., Fatkina, A., Fedoseev, D., Fekete, V., Feng, L. C., Feng, Q. C., Fiorentini, G., Ford, R., Formozov, A., Fournier, A., Franke, S., Gallo, J. P., Gan, H. N., Gao, F., Garfagnini, A., Göttel, A., Genster, C., Giammarchi, M., Giaz, A., Giudice, N., Giuliani, F., Gonchar, M., Gong, G. H., Gong, H., Gorchakov, O., Gornushkin, Y., Grassi, M., Grewing, C., Gromov, M., Gromov, V., Gu, M. H., Gu, W. Q., Gu, X. F., Gu, Y., Guan, M. Y., Guardone, N., Gul, M., Guo, C., Guo, J. Y., Guo, L., Guo, W. L., Guo, X. H., Guo, Y. H., Guo, Z., Haacke, M., Hackenburg, R. W., Hackspacher, P., Hagner, C., Han, R., Han, Y., Hans, S., He, M., He, W., Heeger, K. M., Heinz, T., Heng, Y. K., Herrera, R., Higuera, A., Hong, D. J., Hor, Y. K., Hou, S. J., Hsiung, Y. B., Hu, B. Z., Hu, H., Hu, J. R., Hu, J., Hu, S. Y., Hu, T., Hu, Z. J., Huang, C. H., Huang, G. H., Huang, H. X., Huang, Q. H., Huang, W. H., Huang, X. T., Huang, Y. B., Huber, P., Hui, J. Q., Huo, L., Huo, W. J., Huss, C., Hussain, S., Insolia, A., Ioannisian, A., Ioannisyan, D., Isocrate, R., Jaffe, D. E., Jen, K. L., Ji, X. L., Ji, X. P., Ji, X. Z., Jia, H. H., Jia, J. J., Jian, S. Y., Jiang, D., Jiang, X. S., Jin, R. Y., Jing, X. P., Johnson, R. A., Jollet, C., Jones, D., Joutsenvaara, J., Jungthawan, S., Kalousis, L., Kampmann, P., Kang, L., Karagounis, M., Kazarian, N., Kettell, S. H., Khan, A., Khan, W., Khosonthongkee, K., Kinz, P., Kohn, S., Korablev, D., Kouzakov, K., Kramer, M., Krasnoperov, A., Krokhaleva, S., Krumshteyn, Z., Kruth, A., Kutovskiy, N., Kuusiniemi, P., Lachacinski, B., Lachenmaier, T., Langford, T. J., Lee, J., Lee, J. H. C., Lefevre, F., Lei, L., Lei, R., Leitner, R., Leung, J., Li, C., Li, D. M., Li, F., Li, H. T., Li, H. L., Li, J., Li, J. J., Li, J. Q., Li, K. J., Li, M. Z., Li, N., Li, Q. J., Li, R. H., Li, S. C., Li, S. F., Li, S. J., Li, T., Li, W. D., Li, W. G., Li, X. M., Li, X. N., Li, X. L., Li, X. Q., Li, Y., Li, Y. F., Li, Z. B., Li, Z. Y., Liang, H., Liang, J. J., Liebau, D., Limphirat, A., Limpijumnong, S., Lin, C. J., Lin, G. L., Lin, S. X., Lin, T., Lin, Y. H., Ling, J. J., Link, J. M., Lippi, I., Littenberg, L., Littlejohn, B. R., Liu, F., Liu, H., Liu, H. B., Liu, H. D., Liu, H. J., Liu, H. T., Liu, J. C., Liu, J. L., Liu, M., Liu, Q., Liu, R. X., Liu, S. Y., Liu, S. B., Liu, S. L., Liu, X. W., Liu, Y., Lokhov, A., Lombardi, P., Loo, K., Lorenz, S., Lu, C., Lu, H. Q., Lu, J. B., Lu, J. G., Lu, S. X., Lu, X. X., Lubsandorzhiev, B., Lubsandorzhiev, S., Ludhova, L., Luk, K. B., Luo, F. J., Luo, G., Luo, P. W., Luo, S., Luo, W. M., Lyashuk, V., Ma, Q. M., Ma, S., Ma, X. B., Ma, X. Y., Ma, Y. Q., Malyshkin, Y., Mantovani, F., Mao, Y. J., Mari, S. M., Marini, F., Marium, S., Marshall, C., Martellini, C., Martin-Chassard, G., Caicedo, D. A. Martinez, Martini, A., Martino, J., Mayilyan, D., McDonald, K. T., McKeown, R. D., Müller, A., Meng, G., Meng, Y., Meregaglia, A., Meroni, E., Meyhöfer, D., Mezzetto, M., Miller, J., Miramonti, L., Monforte, S., Montini, P., Montuschi, M., Morozov, N., Muralidharan, P., Napolitano, J., Nastasi, M., Naumov, D. V., Naumova, E., Nemchenok, I., Nikolaev, A., Ning, F. P., Ning, Z., Nunokawa, H., Oberauer, L., Ochoa-Ricoux, J. P., Olshevskiy, A., Ortica, F., Pan, H. R., Paoloni, A., Park, J., Parkalian, N., Parmeggiano, S., Patton, S., Payupol, T., Pec, V., Pedretti, D., Pei, Y. T., Pelliccia, N., Peng, A. G., Peng, H. P., Peng, J. C., Perrot, F., Petitjean, P. A., Rico, L. F. Pineres, Popov, A., Poussot, P., Pratumwan, W., Previtali, E., Pun, C. S. J., Qi, F. Z., Qi, M., Qian, S., Qian, X., Qian, X. H., Qiao, H., Qin, Z. H., Qiu, S. K., Rajput, M., Ranucci, G., Raper, N., Re, A., Rebber, H., Rebii, A., Ren, B., Ren, J., Reveco, C. M., Rezinko, T., Ricci, B., Robens, M., Roche, M., Rodphai, N., Rohwer, L., Romani, A., Rosero, R., Roskovec, B., Roth, C., Ruan, X. C., Ruan, X. D., Rujirawat, S., Rybnikov, A., Sadovsky, A., Saggese, P., Salamanna, G., Sangka, A., Sanguansak, N., Sawangwit, U., Sawatzki, J., Sawy, F., Schever, M., Schuler, J., Schwab, C., Schweizer, K., Selivanov, D., Selyunin, A., Serafini, A., Settanta, G., Settimo, M., Shahzad, M., Shi, G., Shi, J. Y., Shi, Y. J., Shutov, V., Sidorenkov, A., Simkovic, F., Sirignano, C., Siripak, J., Sisti, M., Slupecki, M., Smirnov, M., Smirnov, O., Sogo-Bezerra, T., Songwadhana, J., Soonthornthum, B., Sotnikov, A., Sramek, O., Sreethawong, W., Stahl, A., Stanco, L., Stankevich, K., Stefanik, D., Steiger, H., Steiner, H., Steinmann, J., Stender, M., Strati, V., Studenikin, A., Sun, G. X., Sun, L. T., Sun, J. L., Sun, S. F., Sun, X. L., Sun, Y. J., Sun, Y. Z., Suwonjandee, N., Szelezniak, M., Tang, J., Tang, Q., Tang, X., Tietzsch, A., Tkachev, I., Tmej, T., Treskov, K., Troni, G., Trzaska, W., Tse, W. -H., Tull, C. E., Tuve, C., van Waasen, S., Boom, J. Vanden, Vassilopoulos, N., Vedin, V., Verde, G., Vialkov, M., Viaud, B., Viren, B., Volpe, C., Vorobel, V., Votano, L., Walker, P., Wang, C., Wang, C. H., Wang, E., Wang, G. L., Wang, J., Wang, K. Y., Wang, L., Wang, M. F., Wang, M., Wang, N. Y., Wang, R. G., Wang, S. G., Wang, W., Wang, W. S., Wang, X., Wang, X. Y., Wang, Y., Wang, Y. F., Wang, Y. G., Wang, Y. M., Wang, Y. Q., Wang, Z., Wang, Z. M., Wang, Z. Y., Watcharangkool, A., Wei, H. Y., Wei, L. H., Wei, W., Wei, Y. D., Wen, L. J., Whisnant, K., White, C. G., Wiebusch, C., Wong, S. C. F., Wong, H. L. H., Wonsak, B., Worcester, E., Wu, C. H., Wu, D. R., Wu, F. L., Wu, Q., Wu, W. J., Wu, Z., Wurm, M., Wurtz, J., Wysotzki, C., Xi, Y. F., Xia, D. M., Xie, Y. G., Xie, Z. Q., Xing, Z. Z., Xu, D. L., Xu, F. R., Xu, H. K., Xu, J. L., Xu, J., Xu, M. H., Xu, T., Xu, Y., Xue, T., Yan, B. J., Yan, X. B., Yan, Y. P., Yang, A. B., Yang, C. G., Yang, H., Yang, J., Yang, L., Yang, X. Y., Yang, Y. F., Yang, Y. Z., Yao, H. F., Yasin, Z., Ye, J. X., Ye, M., Yegin, U., Yeh, M., Yermia, F., Yi, P. H., You, Z. Y., Young, B. L., Yu, B. X., Yu, C. X., Yu, C. Y., Yu, H. Z., Yu, M., Yu, X. H., Yu, Z. Y., Yuan, C. Z., Yuan, Y., Yuan, Z. X., Yuan, Z. Y., Yue, B. B., Zafar, N., Zambanini, A., Zeng, P., Zeng, S., Zeng, T. X., Zeng, Y. D., Zhan, L., Zhang, C., Zhang, F. Y., Zhang, G. Q., Zhang, H. H., Zhang, H. Q., Zhang, J., Zhang, J. B., Zhang, J. W., Zhang, P., Zhang, Q. M., Zhang, T., Zhang, X. M., Zhang, X. T., Zhang, Y., Zhang, Y. H., Zhang, Y. M., Zhang, Y. P., Zhang, Y. X., Zhang, Y. Y., Zhang, Z. J., Zhang, Z. P., Zhang, Z. Y., Zhao, F. Y., Zhao, J., Zhao, R., Zhao, S. J., Zhao, T. C., Zheng, D. Q., Zheng, H., Zheng, M. S., Zheng, Y. H., Zhong, W. R., Zhou, J., Zhou, L., Zhou, N., Zhou, S., Zhou, X., Zhu, J., Zhu, K. J., Zhuang, H. L., Zong, L., and Zou, J. H.

Subjects
Physics - Instrumentation and Detectors, High Energy Physics - Experiment
Abstract

To maximize the light yield of the liquid scintillator (LS) for the Jiangmen Underground Neutrino Observatory (JUNO), a 20 t LS sample was produced in a pilot plant at Daya Bay. The optical properties of the new LS in various compositions were studied by replacing the gadolinium-loaded LS in one antineutrino detector. The concentrations of the fluor, PPO, and the wavelength shifter, bis-MSB, were increased in 12 steps from 0.5 g/L and <0.01 mg/L to 4 g/L and 13 mg/L, respectively. The numbers of total detected photoelectrons suggest that, with the optically purified solvent, the bis-MSB concentration does not need to be more than 4 mg/L. To bridge the one order of magnitude in the detector size difference between Daya Bay and JUNO, the Daya Bay data were used to tune the parameters of a newly developed optical model. Then, the model and tuned parameters were used in the JUNO simulation. This enabled to determine the optimal composition for the JUNO LS: purified solvent LAB with 2.5 g/L PPO, and 1 to 4 mg/L bis-MSB., Comment: 13 pages, 8 figures

Published
2020

102. Search for millicharged particles in proton-proton collisions at $\sqrt{s} = 13$ TeV

Author

Ball, A., Beauregard, G., Brooke, J., Campagnari, C., Carrigan, M., Citron, M., De La Haye, J., De Roeck, A., Elskens, Y., Franco, R. Escobar, Ezeldine, M., Francis, B., Gastal, M., Ghimire, M., Goldstein, J., Golf, F., Guiang, J., Haas, A., Heller, R., Hill, C. S., Lavezzo, L., Loos, R., Lowette, S., Magill, G., Manley, B., Marsh, B., Miller, D. W., Odegard, B., Saab, F. R., Sahili, J., Schmitz, R., Setti, F., Shakeshaft, H., Stuart, D., Swiatlowski, M., Yoo, J., Zaraket, H., and Zheng, H.

Subjects
High Energy Physics - Experiment, Physics - Instrumentation and Detectors
Abstract

We report on a search for elementary particles with charges much smaller than the electron charge using a data sample of proton-proton collisions provided by the CERN Large Hadron Collider in 2018, corresponding to an integrated luminosity of 37.5 fb$^{-1}$ at a center-of-mass energy of 13 TeV. A prototype scintillator-based detector is deployed to conduct the first search at a hadron collider sensitive to particles with charges ${\leq}0.1e$. The existence of new particles with masses between 20 and 4700 MeV is excluded at 95% confidence level for charges between $0.006e$ and $0.3e$, depending on their mass. New sensitivity is achieved for masses larger than $700$ MeV.

Published
2020
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103. Intertwined density waves in a metallic nickelate

Author

Zhang, J., Phelan, D., Botana, A. S., Chen, Y-S., Zheng, H., Krogstad, M., Wang, S. G., Qiu, Y., Rodriguez-Rivera, J. A., Osborn, R., Rosenkranz, S., Norman, M. R., and Mitchell, J. F.

Subjects
Condensed Matter - Strongly Correlated Electrons, Condensed Matter - Materials Science
Abstract

Nickelates are a rich class of materials, ranging from insulating magnets to superconductors. But for stoichiometric materials, insulating behavior is the norm, as for most late transition metal oxides. Notable exceptions are the 3D perovskite LaNiO$_3$, an unconventional paramagnetic metal, and the layered Ruddlesden-Popper phases R$_4$Ni$_3$O$_{10}$, (R=La, Pr, Nd). The latter are particularly intriguing because they exhibit an unusual metal-to-metal transition. Here, we demonstrate that this transition results from an incommensurate density wave with both charge and magnetic character that lies intermediate in behavior between the metallic density wave seen in chromium metal and the insulating stripes typically found in layered nickelates. As such, R$_4$Ni$_3$O$_{10}$, which appears to be the first known example of an itinerant spin density wave in a 3d transition metal oxide, represents an important bridge between the paramagnetism of 3D metallic LaNiO$_3$ at higher nickel valence and the polaronic behavior of quasi-2D R$_{2-x}$Sr$_x$NiO$_4$ at lower nickel valence.

Published
2020
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104. Nuclear modification factor in Pb-Pb and p-Pb collisions using Boltzmann transport equation

Author

Qiao, L., Che, G., Gu, J., Zheng, H., and Zhang, W. C.

Subjects
Nuclear Theory
Abstract

We investigate the nuclear modification factor ($R_{AA}$) of identified particles as a function of transverse momentum ($p_{\rm T}$) in Pb-Pb collisions at $\sqrt{s_{\rm NN}}=$ 2.76 and 5.02 TeV, as well as p-Pb collision at 5.02 TeV in the framework of Boltzmann transport equation with relaxation time approximation. In this framework, the initial distribution of particles is chosen as the Tsallis distribution and the local equilibrium distribution as the Boltzmann-Gibbs blast-wave distribution. The non-extensive parameter $q_{pp}$, the Tsallis temperature $T_{pp}$ and the equilibrium temperature $T_{eq}$ are set to be in common for all particles, while the ratio of kinetic freeze-out time to relaxation time $t_{f}/\tau$ is different for different particles when we performed a combined fit to the $R_{AA}$ spectra of different particles at a given centrality. We observe that the fitted curves describe the spectra well up to $p_{\rm T}\approx$ 3 GeV/c. $q_{pp}$ and $T_{eq}$ ($t_{f}/\tau$) decrease (increases) with centrality nonlinearly, while $T_{pp}$ is almost independent of centrality. The dependence of the rate at which $q_{pp}$, $T_{eq}$ or $t_{f}/\tau$ changes with centrality on the energy and the size of the colliding system is discussed., Comment: 14 pages, 6 figures. Accepted by J. Phys. G

Published
2020
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106. Electronic nature of chiral charge order in the kagome superconductor Cs V3Sb5

Author

Wang, Z, Jiang, YX, Yin, JX, Li, Y, Wang, GY, Huang, HL, Shao, S, Liu, J, Zhu, P, Shumiya, N, Hossain, MS, Liu, H, Shi, Y, Duan, J, Li, X, Chang, G, Dai, P, Ye, Z, Xu, G, Wang, Y, Zheng, H, Jia, J, Hasan, MZ, and Yao, Y

Abstract

Kagome superconductors with TC up to 7 K have been discovered for over 40 y. Recently, unconventional chiral charge order has been reported in kagome superconductor KV3Sb5, with an ordering temperature of one order of magnitude higher than the TC. However, the chirality of the charge order has not been reported in the cousin kagome superconductor CsV3Sb5, and the electronic nature of the chirality remains elusive. In this paper, we report the observation of electronic chiral charge order in CsV3Sb5 via scanning tunneling microscopy (STM). We observe a 2 × 2 charge modulation and a 1 × 4 superlattice in both topographic data and tunneling spectroscopy. 2 × 2 charge modulation is highly anticipated as a charge order by fundamental kagome lattice models at van Hove filling, and is shown to exhibit intrinsic chirality. We find that the 1 × 4 superlattices form various small domain walls, and can be a surface effect as supported by our first-principles calculations. Crucially, we find that the amplitude of the energy gap opened by the charge order exhibits real-space modulations, and features 2 × 2 wave vectors with chirality, highlighting the electronic nature of the chiral charge order. STM study at 0.4 K reveals a superconducting energy gap with a gap size 2Δ=0.85meV, which estimates a moderate superconductivity coupling strength with 2Δ/kBTC=3.9. When further applying a c-axis magnetic field, vortex core bound states are observed within this gap, indicative of clean-limit superconductivity.

Published
2021

107. Robust topological state against magnetic impurities observed in the superconductor PbTaSe2

Author

Multer, D, Yin, JX, Zhang, SS, Zheng, H, Chang, TR, Bian, G, Sankar, R, and Hasan, MZ

Abstract

Magnetic impurities deposited on topological superconductor candidate PbTaSe2 can introduce a nonsplitting zero-energy state inside the superconducting gap, which has been proposed as a field-free platform for topological zero modes. However, it is still unclear how robust the topological state in PbTaSe2 is against magnetic impurities, which is related to the topological nature of the zero-energy state as well as its potential for quantum computation. In this paper, we use scanning tunneling microscopy to study the topological surface state in the normal state of PbTaSe2 under the perturbation of magnetic impurities. We visualize the quasiparticle interference (QPI) arising from the topological surface state. We then deposit Fe impurities on the surface to form atomic Fe adatoms. We find that each Fe adatom sits at a unique interstitial position on the surface and features a local state at high energies, both of which are consistent with our first-principles calculation that further reveals its large magnetic moment. Our systematic Fe deposition and subsequent measurements show that the arclike QPI pattern at the Fermi energy is robust with up to 3% Fe coverage where the atomic nature of Fe adatoms still holds. Our results provide evidence that the topological surface state at the Fermi energy in PbTaSe2 is robust against dilute magnetic impurities.

Published
2021

108. Lipid Metabolism Reprogramming of Immune Cells in Acne: An Update

Author

Wu S, Zhang X, Wang Y, Zheng H, and Zhu M

Subjects
acne vulgaris, inflammatory response, lipid, reprogramming, Dermatology, RL1-803
Abstract

Shuhui Wu,1 Xi Zhang,2 Yun Wang,1 Huie Zheng,1 Mingfang Zhu1 1Department of Dermatology, Key Laboratory of Vascular Biology and Translational Medicine, Education Department of Hunan Province, The Second Affiliated Hospital of Hunan University of Chinese Medicine, Changsha, Hunan, People’s Republic of China; 2Department of Physical Education and Health Promotion, Hunan University of Technology and Business, Changsha, Hunan, People’s Republic of ChinaCorrespondence: Mingfang Zhu, Department of Dermatology, Key Laboratory of Vascular Biology and Translational Medicine, Education Department of Hunan Province, The Second Affiliated Hospital of Hunan University of Chinese Medicine, 233 Caie North Road, Kaifu District, Changsha, Hunan, People’s Republic of China, Tel/Fax +86 731 8491 7727, Email 320492@hnucm.edu.cnAbstract: Acne vulgaris is one of the most widespread skin conditions and the main reason for visiting a dermatologist. Inflammatory response and abnormal infiltrations of immune cells are the main pathogenesis of acne. The increased lipid is the prerequisite for the acne, and the perturbation of lipid composition and content is consistent with the severity of acne. Furthermore, the increased lipid production not only contributes to the occurrence and development of acne, but also sensitizes the function of immune cells. The lipid metabolic dysfunction aggravates the severity of local tissue and provides pro-inflammatory-cytokine cues, which indicates the crucial roles of lipid metabolism on immune cells. Recent advances have demonstrated the lipid metabolism reprogramming of various immune cells in acne lesion. The abnormal lipid accumulation, lipolysis, and fatty acid oxidation lead to the activation and differentiation of immune cells, which promotes the pro-inflammatory cytokines production. Thus, this review discusses the emerging role of lipid metabolism reprogramming of immune cells in the progress of acne and aims to constitute food for others’ projects involved in acne research.Keywords: acne vulgaris, inflammatory response, lipid, reprogramming

Published
2023

109. Alterations in the Gut Microbiome of Young Children with Airway Allergic Disease Revealed by Next-Generation Sequencing

Author

Wan J, Song J, Lv Q, Zhang H, Xiang Q, Dai H, Zheng H, Lin X, and Zhang W

Subjects
childhood；allergic asthma；allergic rhinitis；gut microbiome；metagenomic sequencing, Immunologic diseases. Allergy, RC581-607
Abstract

Jinyi Wan,1,2,&ast; Jingjing Song,1,&ast; Qingqing Lv,2 Hui Zhang,1 Qiangwei Xiang,1 Huan Dai,1 Hang Zheng,1 Xixi Lin,3 Weixi Zhang1 1Department of Pediatric Allergy and Immunology, The Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, Wenzhou, 325027, People’s Republic of China; 2Department of Pediatric Internal Medicine, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, 317000, People’s Republic of China; 3Department of Pharmacy, The Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, Wenzhou, 325027, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Xixi Lin; Weixi Zhang, Email lxx592604326@163.com; zhangweixi112@163.comPurpose: Recent studies had shown that gut microbiota played a significant role in the development of the immune system and may affect the course of airway allergic disease. We conducted this study to determine unique gut microbial associated with allergic disease in children by shotgun gene sequencing.Methods: We collected fecal samples from children with allergic asthma (n = 23) and allergic rhinitis (n = 18), and healthy control (n = 19). The gut microbiota of specimens was analyzed by high-throughput metagenomic shotgun gene sequencing.Results: The intestinal microbiota of children with allergic asthma and allergic rhinitis was characterized by increased microbial richness and diversity. Simpson and Shannon were significantly elevated in children with allergic asthma. Principal coordinates analysis (PCoA) showed that the gut microbial communities cluster patterns of children with asthma or rhinitis were significantly different from those of healthy controls. However, no significant difference was found between asthma group and rhinitis group At the phylum level, higher relative abundance of Firmicutes was found in the allergic rhinitis group and allergic asthma group, while the level of Bacteroidetes was significantly lower. At the genus level, Corynebacterium, Streptococcus, Dorea, Actinomyces, Bifidobacterium, Blautia, and Rothia were significantly enriched in the allergic asthma group. Finally, a random forest classifier model selected 16 general signatures to discriminate the allergic asthma group from the healthy control group.Conclusion: In conclusion, children in the allergic rhinitis group and allergic asthma group had altered gut microbiomes in comparison with the healthy control group. Compared to healthy children, the gut microbiome in children with allergic diseases has higher pro-inflammatory potential and increased production of pro-inflammatory molecules.Keywords: childhood, allergic asthma, allergic rhinitis, gut microbiome, metagenomic sequencing

Published
2023

110. Correlation of Serum Clara Cell Secretory Protein 16, Plasma Fibrinogen and Serum Amyloid A with the Severity of Acute Exacerbated COPD and Their Combination in Prognosis Assessment

Author

Hu X, Xu J, Li P, and Zheng H

Subjects
aecopd, cc16, fib, saa, Diseases of the respiratory system, RC705-779
Abstract

Xiaojuan Hu,1,&ast; Jin Xu,1,&ast; Pei Li,2 Hui Zheng3 1Department of Pulmonary and Critical Care Medicine, Shanghai Fourth People’s Hospital, School of Medicine, Tongji University, Shanghai, 200434, People’s Republic of China; 2Department of Nephrology, the Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, 050004, People’s Republic of China; 3Department of Clinical Laboratory, Fudan University Shanghai Cancer Center, Shanghai, 200032, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Xiaojuan Hu, Department of Pulmonary and Critical Care Medicine, Shanghai Fourth People’s Hospital, School of Medicine, Tongji University, Shanghai, 200434, People’s Republic of China, Tel +86-13524811465, Email hxj819@126.com Hui Zheng, Department of Clinical Laboratory, Fudan University Shanghai Cancer Center, Shanghai, 200032, People’s Republic of China, Tel +86-18017317741, Email zh19841207xx@163.comIntroduction: Chronic obstructive pulmonary disease (COPD) has tremendous detrimental effects on patients’ quality of life, lung function, disease progression and socioeconomic burden. This study aimed to investigate new serum biomarkers for COPD detection. Three recently emerging biomarkers, including Clara cell secretory protein⁃16 (CC16), plasma fibrinogen (FIB) and serum amyloid A (SAA), were investigated for their potential in stratifying the severity of COPD.Methods: A total of 220 patients with AECOPD were recruited. Multivariate logistical regression was used to analyze odds ratios of an array of characteristic of patients, including age, global initiative for chronic obstructive lung disease (GOLD), diabetes mellitus, heart diseases, PaCO2, CC16, FIB, and SAA. Correlations of CC16, FIB and SAA levels to each other, GOLD, and PaCO2 were also measured using Spearman correlation. Receiver operating characteristic (ROC)/curve analysis was used to assess sensitivity and specificity of CC16, FIB, SAA and the combination of the three markers in identifying AECOPD patients with poor prognosis.Results: Our data suggested that age, GOLD, diabetes mellitus, heart diseases, PaCO2, CC16, FIB, and SAA are all significant risk factors for poor prognosis of AECOPD. CC16, FIB and SAA were positively correlated to each other and to GOLD and PaCO2 levels. CC16, FIB and SAA all had a high sensitivity and specificity in identifying patients with a poor prognosis. CC16, FIB and SAA are new markers with potentially high predictive value in AECOPD.Discussion: Our data support further development of these biomarkers to improve clinical management of AECOPD through providing more accurate prognosis of AECOPD patients that enable timely adjustment of treatment plans.Keywords: AECOPD, CC16, FIB, SAA

Published
2023

111. Emerging Trends and Focus in Human Skin Microbiome Over the Last Decade: A Bibliometric Analysis and Literature Review

Author

Deng T, Zheng H, Zhu Y, Liu M, He G, Li Y, Liu Y, Wu J, and Cheng H

Subjects
skin microbiome, bibliometric, trends, skin barrier, skin immune, Dermatology, RL1-803
Abstract

Tinghan Deng,1 Huilan Zheng,1 Ying Zhu,2 Ming Liu,3 Guanjin He,1 Ya Li,1 Yichen Liu,1 Jingping Wu,4 Hongbin Cheng1 1Department of Dermatology, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan Province, 610075, People’s Republic of China; 2Department of Gynecology, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan Province, 610075, People’s Republic of China; 3Department of Medical Oncology/Gastric Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan Province, 610041, People’s Republic of China; 4Department of Medical Cosmetology, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan Province, 610075, People’s Republic of ChinaCorrespondence: Jingping Wu; Hongbin Cheng, Email wujingping@cdutcm.edu.cn; chenghongbin@cdutcm.edu.cnBackground: Human skin microbiome is the first barrier against exogenous attack and is associated with various skin disease pathogenesis and progression. Advancements in high-throughput sequencing technologies have paved the way for a deeper understanding of this field. Based on the bibliometric analysis, this investigation aimed to identify the hotspots and future research trends associated with human skin microbiomes studied over the past decade.Methods: The published research on skin microbiome from January 2013 to January 2023 was retrieved from the Web of Science Core Collection. Data cleaning processes to ensure robust data and the bibliometrix packages R, CiteSpace, VOSviewer, Origin, and Scimago Graphica for bibliometric and visual analyses were utilized.Results: A total of 1629 published documents were analyzed. The overall publication trend steadily increased, with relatively fast growth in 2017 and 2020. The United States of America has the highest number of publications and citations and shows close collaborations with China and Germany. The University of California, San Diego, indicated a higher number of publications than other institutions and the fastest growth rate. The top three most publishing journals on this topic are Microorganisms, Frontiers in Microbiology, and Experimental dermatology. Gallo RL is the most influential author with the highest h- and g-index and most publications in skin microecology, followed by Grice EA and Kong HH. The top 10 most frequently used keywords in recent years included skin microbiome, microbiome, staphylococcus aureus, diversity, atopic dermatitis, skin, bacteria, infections, gut microbiota, and disease.Conclusion: The skin microbiome is an area of research that requires continuous analysis, and even with much-achieved progress, future research will further be aided as technology develops.Keywords: skin microbiome, bibliometric, trends, skin barrier, skin immune

Published
2023

112. Detection of NDM-1 and OXA-10 Co-Producing Providencia rettgeri Clinical Isolate

Author

Li Y, Shao K, Cai R, Liu Y, Liu X, Ni F, Zheng H, Hu R, and Sun T

Subjects
antimicrobial resistance, blandm-1, blaoxa-10, providencia rettgeri, carbapenemase-producing, average nucleotide identity, phylogenetic, Infectious and parasitic diseases, RC109-216
Abstract

Yaling Li,1,&ast; Kaiyang Shao,1,&ast; Ruyi Cai,1 Yi Liu,2 Xiaojing Liu,2,3 Feihua Ni,1 Huiyan Zheng,1 Ruying Hu,1 Ting Sun1 1Department of Health Management Center, the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, People’s Republic of China; 2Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, People’s Republic of China; 3Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, Shandong, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Ting Sun, Department of Health Management Center, the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310009, Zhejiang, People’s Republic of China, Email 1195037@zju.edu.cnBackground: The coexistence of blaNDM-1 with other resistance determinants is rarely reported for Providencia rettgeri. Therefore, this study investigates the phenotypic and genetic characteristics of a multidrug-resistant P. rettgeri strain YQ150713.Methods: P. rettgeri YQ150713 was identified as carrying blaNDM-1. S1-pulsed-field gel electrophoresis (S1-PFGE), Southern blotting, and conjugation experiments were used to determine plasmid characteristics. An antimicrobial susceptibility test was conducted. The complete genomic sequence of YQ150713 was obtained using Illumina NovaSeq 6000 and Oxford nanopore platforms. To further characterize the phylogenetic structure of P. rettgeri YQ150713, average nucleotide identity (ANI) and phylogenetic analyses were conducted.Results: The S1-PFGE, Southern blot, and conjugation assays have confirmed that the isolate P. rettgeri YQ150713 contains the blaNDM-1 gene on a conjugative plasmid pYQ150713-NDM-1. Antimicrobial susceptibility testing has indicated that strain YQ150713 was resistant to various common antibiotics, except aztreonam and fosfomycin. Bioinformatics analysis has further shown that pYQ150713-NDM-1 was a novel plasmid with a size of 265,883 bp, and blaNDM-1 and blaOXA-10 were co-located on it. Phylogenetic analysis suggesting P. rettgeri has spread widely throughout the world.Conclusion: In this study, blaNDM-1 and blaOXA-10 were co-localized on a novel plasmid pYQ150713-NDM-1 with a horizontal transfer function. To reduce the risk of the dissemination of such P. rettgeri isolates in clinical settings, more surveillance will be required in the future.Keywords: antimicrobial resistance, blaNDM-1, blaOXA-10, Providencia rettgeri, carbapenemase-producing, average nucleotide identity, phylogenetic

Published
2023

113. Imaging, understanding, and control of nanoscale materials transformations

Author

Zheng, H

Subjects
Nucleation and growth, Self-assembly, Electrode-electrolyte interfaces, Liquid cells, Liquid phase TEM, Macromolecular and Materials Chemistry, Materials Engineering, Mechanical Engineering, Applied Physics
Abstract

The development of liquid cells for transmission electron microscopy has enabled breakthroughs in our ability to follow nanoscale structural, morphological, or chemical changes during materials growth and applications. Time-resolved high-resolution imaging and chemical analysis through liquids opened the opportunity to capture nanoscale dynamic processes of materials, including reaction intermediates and the transformation pathways. In this article, a series of work is highlighted with topics ranging from liquid cell developments to in situ studies of nanocrystal growth and transformations, dendrite formation, and suppression of lithium dendrites through in situ characterization of the solid–electrolyte interphase chemistry. The understanding garnered is expected to accelerate the discovery of novel materials for applications in energy storage, catalysis, sensors, and other functional devices.

Published
2021

116. Understanding the HERA Phase i receiver system with simulations and its impact on the detectability of the EoR delay power spectrum

Author

Fagnoni, N, De Lera Acedo, E, Deboer, DR, Abdurashidova, Z, Aguirre, JE, Alexander, P, Ali, ZS, Balfour, Y, Beardsley, AP, Bernardi, G, Billings, TS, Bowman, JD, Bradley, RF, Bull, P, Burba, J, Carilli, CL, Cheng, C, Dexter, M, Dillon, JS, Ewall-Wice, A, Fritz, R, Furlanetto, SR, Gale-Sides, K, Glendenning, B, Gorthi, D, Greig, B, Grobbelaar, J, Halday, Z, Hazelton, BJ, Hewitt, JN, Hickish, J, Jacobs, DC, Josaitis, A, Julius, A, Kern, NS, Kerrigan, J, Kim, H, Kittiwisit, P, Kohn, SA, Kolopanis, M, Lanman, A, Plante, PL, Lekalake, T, Liu, A, Macmahon, D, Malan, L, Malgas, C, Maree, M, Martinot, ZE, Matsetela, E, Mena Parra, J, Mesinger, A, Molewa, M, Morales, MF, Mosiane, T, Neben, AR, Nikolic, B, Parsons, AR, Patra, N, Pieterse, S, Pober, JC, Razavi-Ghods, N, Robnett, J, Rosie, K, Sims, P, Smith, C, Syce, A, Thyagarajan, N, Williams, PKG, and Zheng, H

Subjects
instrumentation: interferometers, methods: numerical, techniques: interferometric, telescopes, dark ages, reionization, first stars, astro-ph.IM, dark ages, reionization, Astronomy & Astrophysics, Astronomical and Space Sciences
Abstract

The detection of the Epoch of Reionization (EoR) delay power spectrum using a 'foreground avoidance method' highly depends on the instrument chromaticity. The systematic effects induced by the radio telescope spread the foreground signal in the delay domain, which contaminates the EoR window theoretically observable. Applied to the Hydrogen Epoch of Reionization Array (HERA), this paper combines detailed electromagnetic and electrical simulations in order to model the chromatic effects of the instrument, and quantify its frequency and time responses. In particular, the effects of the analogue receiver, transmission cables, and mutual coupling are included. These simulations are able to accurately predict the intensity of the reflections occurring in the 150-m cable which links the antenna to the backend. They also show that electromagnetic waves can propagate from one dish to another one through large sections of the array due to mutual coupling. The simulated system time response is attenuated by a factor 104 after a characteristic delay which depends on the size of the array and on the antenna position. Ultimately, the system response is attenuated by a factor 105 after 1400 ns because of the reflections in the cable, which corresponds to characterizable ka-modes above 0.7 $h\,\,\rm {Mpc}^{-1}$ at 150 MHz. Thus, this new study shows that the detection of the EoR signal with HERA Phase I will be more challenging than expected. On the other hand, it improves our understanding of the telescope, which is essential to mitigate the instrument chromaticity.

Published
2021

118. Persistent gapless surface states in MnBi2Te4/Bi2Te3 superlattice antiferromagnetic topological insulator

Author

Xu, L. X., Mao, Y. H., Wang, H. Y., Li, J. H., Chen, Y. J., Xia, Y. Y. Y., Li, Y. W., Zhang, J., Zheng, H. J., Huang, K., Zhang, C. F., Cui, S. T., Liang, A. J., Xia, W., Su, H., Jung, S. W., Cacho, C., Wang, M. X., Li, G., Xu, Y., Guo, Y. F., Yang, L. X., Liu, Z. K., and Chen, Y. L.

Subjects
Condensed Matter - Materials Science
Abstract

Magnetic topological quantum materials (TQMs) provide a fertile ground for the emergence of fascinating topological magneto-electric effects. Recently, the discovery of intrinsic antiferromagnetic (AFM) topological insulator MnBi2Te4 that could realize quantized anomalous Hall effect and axion insulator phase ignited intensive study on this family of TQM compounds. Here, we investigated the AFM compound MnBi4Te7 where Bi2Te3 and MnBi2Te4 layers alternate to form a superlattice. Using spatial- and angle-resolved photoemission spectroscopy, we identified ubiquitous (albeit termination dependent) topological electronic structures from both Bi2Te3 and MnBi2Te4 terminations. Unexpectedly, while the bulk bands show strong temperature dependence correlated with the AFM transition, the topological surface states show little temperature dependence and remain gapless across the AFM transition. The detailed electronic structure of MnBi4Te7 and its temperature evolution, together with the results of its sister compound MnBi2Te4, will not only help understand the exotic properties of this family of magnetic TQMs, but also guide the design for possible applications., Comment: 22 pages, 4 figures

Published
2019
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119. Observation of Topological Electronic Structure in Quasi-1D Superconductor TaSe3

Author

Chen, C, Liang, A, Liu, S, Nie, S, Huang, J, Wang, M, Li, Y, Pei, D, Yang, H, Zheng, H, Zhang, Y, Lu, D, Hashimoto, M, Barinov, A, Jozwiak, C, Bostwick, A, Rotenberg, E, Kou, X, Yang, L, Guo, Y, Wang, Z, Yuan, H, Liu, Z, and Chen, Y

Subjects
cond-mat.mtrl-sci, cond-mat.supr-con
Abstract

A topological superconductor (TSC) is a new type of superconductor with non-trivial topology in its bulk electronic structure, which has great potential in both fundamental research and application. However, despite the intensive research efforts worldwide, to date only a few intrinsic (non-heterostructures) materials have been proposed as TSC candidates. In this work, following the theoretical prediction, we experimentally studied a newly proposed TSC candidate, TaSe3. The topological non-trivial surface states were directly observed by using angle-resolved photoemission spectroscopy, while the superconductivity of the compound was examined by both transport and scanning tunneling microscopy measurement. Therefore, TaSe3 was proved to be a promising candidate as a TSC, and a promising research platform for the related novel physics phenomena.

Published
2020

120. Understanding the role of water-soluble guar gum binder in reducing capacity fading and voltage decay of Li-rich cathode for Li-ion batteries

Author

Yin, ZW, Zhang, T, Zhang, SJ, Deng, YP, Peng, XX, Wang, JQ, Li, JT, Huang, L, Zheng, H, and Sun, SG

Subjects
Energy, Physical Sciences, Chemical Sciences, Engineering
Abstract

The practical application of high-capacity Li-rich cathode materials is hindered by capacity fading and voltage decay. The capacity fading and voltage decay could be effectively overcome by using water-soluble guar gum (GG) binder instead of traditional polyvinylidene fluoride (PVDF). However, the specific role of the GG binder is not clear yet, though the GG binder can significantly improve the electrochemical performance of Li-rich cathode. To understand the effect of GG binder on the morphology, microstructure of electrode and electrode/electrolyte interfaces, ex-situ scanning electron microscope (SEM), transmission electron microscope (TEM), X-ray adsorption near edge spectroscopy (XANES), in-situ electrochemical impedance spectroscopy (EIS) were applied to comparatively study the charge-discharge processes of Li-rich Li1.2Ni0.2Mn0.6O2 cathode when using GG and PVDF as binders. The results indicate that the GG binder can prevent electrode crack and active material loss, ascribing to the strong mechanical adhesion of GG binder with active material particles and current collector. It has found that the GG binder can also induce the formation of a uniform layer on Li1.2Ni0.2Mn0.6O2 particles’ surface. As a consequence, both the electrolyte decomposition and the electrode corrosion were significantly inhibited. The strong chelation between Mn2+ and polar OH group restrain Mn ion dissolution, which contributes to surface structural transformation mitigation. The present study reveals the role of water-soluble GG binder in reducing capacity fading and voltage decay of Li-rich material and is of great importance in design functional binders for high-performance Li-rich electrodes.

Published
2020

121. Detection of cosmic structures using the bispectrum phase. II. First results from application to cosmic reionization using the Hydrogen Epoch of Reionization Array

Author

Thyagarajan, N, Carilli, CL, Nikolic, B, Kent, J, Mesinger, A, Kern, NS, Bernardi, G, Matika, S, Abdurashidova, Z, Aguirre, JE, Alexander, P, Ali, ZS, Balfour, Y, Beardsley, AP, Billings, TS, Bowman, JD, Bradley, RF, Burba, J, Carey, S, Cheng, C, Deboer, DR, Dexter, M, Acedo, EDL, Dillon, JS, Ely, J, Ewall-Wice, A, Fagnoni, N, Fritz, R, Furlanetto, SR, Gale-Sides, K, Glendenning, B, Gorthi, D, Greig, B, Grobbelaar, J, Halday, Z, Hazelton, BJ, Hewitt, JN, Hickish, J, Jacobs, DC, Julius, A, Kerrigan, J, Kittiwisit, P, Kohn, SA, Kolopanis, M, Lanman, A, La Plante, P, Lekalake, T, Lewis, D, Liu, A, Macmahon, D, Malan, L, Malgas, C, Maree, M, Martinot, ZE, Matsetela, E, Molewa, M, Morales, MF, Mosiane, T, Neben, AR, Parsons, AR, Patra, N, Pieterse, S, Pober, JC, Razavi-Ghods, N, Ringuette, J, Robnett, J, Rosie, K, Sims, P, Smith, C, Syce, A, Williams, PKG, and Zheng, H

Subjects
astro-ph.CO, astro-ph.IM
Abstract

Characterizing the epoch of reionization (EoR) at z 6 via the redshifted 21 cm line of neutral Hydrogen (H i) is critical to modern astrophysics and cosmology, and thus a key science goal of many current and planned low-frequency radio telescopes. The primary challenge to detecting this signal is the overwhelmingly bright foreground emission at these frequencies, placing stringent requirements on the knowledge of the instruments and inaccuracies in analyses. Results from these experiments have largely been limited not by thermal sensitivity but by systematics, particularly caused by the inability to calibrate the instrument to high accuracy. The interferometric bispectrum phase is immune to antenna-based calibration and errors therein, and presents an independent alternative to detect the EoR H i fluctuations while largely avoiding calibration systematics. Here, we provide a demonstration of this technique on a subset of data from the Hydrogen Epoch of Reionization Array (HERA) to place approximate constraints on the brightness temperature of the intergalactic medium (IGM). From this limited data, at z=7.7 we infer "1σ"upper limits on the IGM brightness temperature to be ≤ 316 "pseudo"mK at κ =0.33 "pseudo"h Mpc-1 (data-limited) and ≤ 1000 "pseudo"mK at κ =0.875 "pseudo"h Mpc-1 (noise-limited). The "pseudo"units denote only an approximate and not an exact correspondence to the actual distance scales and brightness temperatures. By propagating models in parallel to the data analysis, we confirm that the dynamic range required to separate the cosmic H i signal from the foregrounds is similar to that in standard approaches, and the power spectrum of the bispectrum phase is still data-limited (at 106 dynamic range) indicating scope for further improvement in sensitivity as the array build-out continues.

Published
2020

122. Unveiling the mechanisms of lithium dendrite suppression by cationic polymer film induced solid-electrolyte interphase modification

Author

Lee, SY, Shangguan, J, Alvarado, J, Betzler, S, Harris, SJ, Doeff, MM, and Zheng, H

Subjects
Energy
Abstract

It is crucial to suppress lithium dendrite formation in lithium metal batteries. Formation of a good solid-electrolyte interphase (SEI) has been considered to be effective in limiting lithium dendrite growth. However, how the SEI may be modified during lithium deposition is hard to resolve due to challenges in in situ investigation of the SEI with fine details. We report an in situ study that uncovers the lithium dendrite suppression mechanism arising from SEI modification by a poly(diallyldimethylammonium chloride) (PDDA) cationic polymer film, using electrochemical liquid cell transmission electron microscopy (TEM). Lithium nanogranules are obtained in the presence of the polymer film. Chemical mapping of the deposits provides remarkable details of the SEI on individual nanogranules. It shows that lithium fluorides are uniformly distributed within the inner SEI layer of individual lithium nanogranules, arising from the instantaneous reaction of the deposited lithium with PF6- ions accumulated by the cationic polymer film, and thus the dendritic growth of lithium is prohibited. The ability to directly measure SEI chemistry at the nanoscale down to the individual nanograins in situ and unveil its correlation with the lithium deposition behavior opens future opportunities to explore unsolved mechanisms in batteries.

Published
2020

123. Electrode roughness dependent electrodeposition of sodium at the nanoscale

Author

Zeng, Z, Barai, P, Lee, SY, Yang, J, Zhang, X, Zheng, W, Liu, YS, Bustillo, KC, Ercius, P, Guo, J, Cui, Y, Srinivasan, V, and Zheng, H

Subjects
Liquid cell TEM, Electrochemical liquid cell, Na deposition, Solid-electrolyte interphase, Sodium ion batteries, Macromolecular and Materials Chemistry, Materials Engineering, Nanotechnology
Abstract

Na metal is an attractive anode material for rechargeable Na ion batteries, however, the dendritic growth of Na can cause serious safety issues. Along with modifications of solid-electrolyte interphase (SEI), engineering the electrode has been reported to be effective in suppressing Na dendritic growth, likely by reducing localized current density accumulation. However, fundamental understanding of Na growth at the nanoscale is still limited. Here, we report an in-situ study of Na electrodeposition in electrochemical liquid cells with the electrodes in different surface roughness, e.g., flat or sharp curvature. Real time observation using transmission electron microscopy (TEM) reveals the Na electrodeposition with remarkable details. Relatively large Na grains (in the micrometer scale) are achieved on the flat electrode surface. The local SEI thickness variations impact the growth rate, thus the morphology of individual grains. In contrast, small Na grains (in tens of nanometers) grow explosively on the electrode at the point with sharp curvature. The newly formed Na grains preferentially deposit at the base of existing grains close to the electrode. Further studies using continuum-based computational modeling suggest that the growth mode of an alkali metal (e.g. Na) is strongly influenced by the transport properties of SEI. Our direct observation of Na deposition in combination with the theoretical modeling provides insights for comprehensive understanding of electrode roughness and SEI effects on Na electrochemical deposition.

Published
2020

124. Foreground modelling via Gaussian process regression: An application to HERA data

Author

Ghosh, A, Mertens, F, Bernardi, G, Santos, MG, Kern, NS, Carilli, CL, Grobler, TL, Koopmans, LVE, Jacobs, DC, Liu, A, Parsons, AR, Morales, MF, Aguirre, JE, Dillon, JS, Hazelton, BJ, Smirnov, OM, Gehlot, BK, Matika, S, Alexander, P, Ali, ZS, Beardsley, AP, Benefo, RK, Billings, TS, Bowman, JD, Bradley, RF, Cheng, C, Chichura, PM, Deboer, DR, Acedo, EDL, Ewall-Wice, A, Fadana, G, Fagnoni, N, Fortino, AF, Fritz, R, Furlanetto, SR, Gallardo, S, Glendenning, B, Gorthi, D, Greig, B, Grobbelaar, J, Hickish, J, Josaitis, A, Julius, A, Igarashi, AS, Kariseb, M, Kohn, SA, Kolopanis, M, Lekalake, T, Loots, A, MacMahon, D, Malan, L, Malgas, C, Maree, M, Martinot, ZE, Mathison, N, Matsetela, E, Mesinger, A, Neben, AR, Nikolic, B, Nunhokee, CD, Patra, N, Pieterse, S, Razavi-Ghods, N, Ringuette, J, Robnett, J, Rosie, K, Sell, R, Smith, C, Syce, A, Tegmark, M, Thyagarajan, N, Williams, PKG, and Zheng, H

Subjects
instrumentation: interferometers, methods: statistical, dark ages, reionization, first stars, diffuse radiation, large-scale structure of Universe, cosmology: observations, astro-ph.CO, dark ages, reionization, first stars, Astronomy & Astrophysics, Astronomical and Space Sciences
Abstract

The key challenge in the observation of the redshifted 21-cm signal from cosmic reionization is its separation from the much brighter foreground emission. Such separation relies on the different spectral properties of the two components, although, in real life, the foreground intrinsic spectrum is often corrupted by the instrumental response, inducing systematic effects that can further jeopardize the measurement of the 21-cm signal. In this paper, we use Gaussian Process Regression to model both foreground emission and instrumental systematics in ∼2 h of data from the Hydrogen Epoch of Reionization Array. We find that a simple co-variance model with three components matches the data well, giving a residual power spectrum with white noise properties. These consist of an 'intrinsic' and instrumentally corrupted component with a coherence scale of 20 and 2.4 MHz, respectively (dominating the line-of-sight power spectrum over scales kâ ≤ 0.2 h cMpc-1) and a baseline-dependent periodic signal with a period of ∼1 MHz (dominating over kâ ∼0.4-0.8 h cMpc-1), which should be distinguishable from the 21-cm Epoch of Reionization signal whose typical coherence scale is ∼0.8 MHz.

Published
2020

125. Dynamic Covalent Synthesis of Crystalline Porous Graphitic Frameworks

Author

Li, X, Wang, H, Chen, H, Zheng, Q, Zhang, Q, Mao, H, Liu, Y, Cai, S, Sun, B, Dun, C, Gordon, MP, Zheng, H, Reimer, JA, Urban, JJ, Ciston, J, Tan, T, Chan, EM, and Zhang, J

Subjects
Macromolecular and Materials Chemistry
Abstract

Porous graphitic framework (PGF) is a two-dimensional (2D) material that has emerging energy applications. An archetype contains stacked 2D layers, the structure of which features a fully annulated aromatic skeleton with embedded heteroatoms and periodic pores. Due to the lack of a rational approach in establishing in-plane order under mild synthetic conditions, the structural integrity of PGF has remained elusive and ultimately limited its material performance. Here, we report the discovery of the unusual dynamic character of the C=N bonds in the aromatic pyrazine ring system under basic aqueous conditions, which enables the successful synthesis of a crystalline porous nitrogenous graphitic framework with remarkable in-plane order, as evidenced by powder X-ray diffraction studies and direct visualization using high-resolution transmission electron microscopy. The crystalline framework displays superior performance as a cathode material for lithium-ion batteries, outperforming the amorphous counterparts in terms of capacity and cycle stability. Insertion of well-defined, evenly spaced nanoscale pores into the two-dimensional (2D) layers of graphene invokes exciting properties due to the modulation of its electronic band gaps and surface functionalities. A bottom-up synthesis approach to such porous graphitic frameworks (PGFs) is appealing but also remains a great challenge. The current methods of building covalent organic frameworks rely on a small collection of thermodynamically reversible reactions. Such reactions are, however, inadequate in generating a fully annulated aromatic skeleton in PGFs. With the discovery of dynamic pyrazine formation, we succeeded in applying this linking chemistry to obtain a crystalline PGF material, which has displayed high electrical conductivity and remarkable performance as a cathode material for lithium-ion batteries. We envision that the demonstrated success will open the door to a wide array of fully annulated 2D porous frameworks, which hold immense potential for clean energy applications. We report the unusual dynamic characteristics of the C=N bonds in the pyrazine ring promoted under basic aqueous conditions, which enables the successful synthesis of two-dimensional porous graphitic frameworks (PGFs) featuring fully annulated aromatic skeletons and periodic pores. The PGF displayed high electrical conductivity and remarkable performance as a cathode material for lithium-ion batteries, far outperforming the amorphous counterparts in terms of capacity and cycle stability.

Published
2020

126. Study on Intestinal Flora and Asthma: Knowledge Graph Analysis Based on CiteSpace (2001–2021)

Author

Zheng H, Dai H, Yan X, and Xiang Q

Subjects
microbiota, allergy, treg cells, probiotics, chain fatty acid., Immunologic diseases. Allergy, RC581-607
Abstract

Hang Zheng, Huan Dai, Xiumei Yan, Qiangwei Xiang Department of Pediatric Allergy and Immunology, The Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, People’s Republic of ChinaCorrespondence: Qiangwei Xiang, Department of Pediatric Allergy and Immunology, The Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, People’s Republic of China, Email 7088269@qq.comAbstract: Asthma is a common chronic inflammatory disease of the airway. Intestinal flora, a significant risk factor for asthma, has become a widespread concern in the pathogenesis of asthma. To review the literature related to intestinal flora in asthma, summarize research direction, and report trends, this study used CiteSpace to perform bibliometric statistics and analysis on the research papers of intestinal flora and asthma collected in the Web of science core collection from 2001 to 2021. Eventually, a total of 613 articles were included. The results demonstrated that research on gut flora and asthma continued to heat up, with article numbers increasing, especially in the last decade. Moreover, analysis of the keywords showed that the research topics of intestinal flora and asthma range from confirming the link between intestinal flora and asthma to investigating mechanisms and then to asthma treatment. According to the summary of research hotspots, we expand on three emerging issues that require attention in the intestinal flora and asthma research, including (regulatory T)Treg cells, probiotics, and chain fatty acid. Evidence illustrated that Treg cells play a crucial role in the pathogenesis of asthma caused by dysbiosis of the gut flora. Furthermore, in contrast to probiotic supplements, which do not reduce the risk of developing asthma, short-chain fatty acids supplements do. Overall, the research direction in the field of intestinal flora and asthma has recently evolved from macro to micro with depth broadened. As a robust scientific evaluation, our study provided a comprehensive overview of the area, particularly for research focus, which could more precisely direct scholars on future research and clinical diagnosis, therapy, and individualized prevention.Keywords: microbiota, allergy, Treg cells, probiotics, chain fatty acid

Published
2023

131. Netrin-1 Monoclonal Antibody-Functionalized Nanoparticle Loaded with Metformin Prevents the Progression of Abdominal Aortic Aneurysms

Author

Zhang Z, Zhuang J, Sun D, Ding Q, Zheng H, Li H, Zhang X, Du Y, Ma T, and Meng Q

Subjects
abdominal aortic aneurysm, nanoparticle, metformin, macrophage, Medicine (General), R5-920
Abstract

Zhiwei Zhang,1,&ast; Jiawei Zhuang,2,&ast; Daohan Sun,3,&ast; Qingwei Ding,1 Hui Zheng,1 Haixiang Li,1 Xiaoyu Zhang,1 Yaming Du,3 Teng Ma,1 Qingyou Meng1 1Department of Vascular Surgery, General Surgery Clinical Center, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China; 2Department of Cardiovascular Surgery, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, People’s Republic of China; 3Department of Vascular Surgery, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Qingyou Meng; Teng Ma, Email mengqy@163.com; m_aeolus@163.comBackground: Abdominal aortic aneurysms (AAAs) are a global health and economic burden. Therapeutic strategies to inhibit the progression of AAAs are currently lacking. Recently, the therapeutic effect of metformin on aneurysms has attracted considerable interest. However, the unfavorable pharmacokinetic properties of metformin limit its feasibility for AAA treatment.Methods and Results: We constructed a metformin-loaded netrin-1-responsive AAA-targeted nanoparticle (Tgt-NP-Met) for AAA management. Evaluation of the therapeutic effect of Tgt-NP-Met was performed by in vitro and in vivo experiments. Our results showed that the binding of netrin-1 monoclonal antibodies enhanced the AAA-targeting capability of nanoparticles (NPs). Moreover, Tgt-NP-Met administration prevented AAA development and reduced the aneurysm diameter in apolipoprotein E (ApoE)-deficient (ApoE−/−) mice that received continuous infusion of angiotensin II. Furthermore, metformin prevented AAA progression by inhibiting the transformation of vascular smooth muscle cells (VSMCs) from a contractile phenotype to a synthetic phenotype, which is mediated by macrophage infiltration and activation.Conclusion: Our findings identify metformin as a functional suppressor for macrophage-mediated phenotypic transformation of VSMCs and Tgt-NP-Met as an efficient therapeutic strategy for AAA management.Graphical Abstract: Keywords: abdominal aortic aneurysm, nanoparticle, metformin, macrophage

Published
2023

132. Biomembrane-Based Nanostructure- and Microstructure-Loaded Hydrogels for Promoting Chronic Wound Healing

Author

Liu WS, Liu Y, Gao J, Zheng H, Lu ZM, and Li M

Subjects
biomembrane, nanostructures, microstructures, hydrogels, chronic wound healing, Medicine (General), R5-920
Abstract

Wen-Shang Liu,1,&ast; Yu Liu,2,&ast; Jie Gao,3,&ast; Hao Zheng,4 Zheng-Mao Lu,4 Meng Li1 1Department of Dermatology, Shanghai Ninth People’s Hospital, Shanghai Jiaotong University, Shanghai, People’s Republic of China; 2Department of Gastroenterology, Jinling Hospital, Medical School of Nanjing University, Nanjing, People’s Republic of China; 3Changhai Clinical Research Unit, Shanghai Changhai Hospital, Naval Medical University, Shanghai, People’s Republic of China; 4Department of General Surgery, Shanghai Changhai Hospital, Naval Medical University, Shanghai, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Meng Li, Department of Dermatology, Shanghai Ninth People’s Hospital, Shanghai Jiaotong University, Shanghai, People’s Republic of China, Tel +086-15000879978, Fax +086-021-23271699, Email lemonlives_dr@163.com Zheng-Mao Lu, Department of General Surgery, Shanghai Changhai Hospital, Naval Medical University, Shanghai, People’s Republic of China, Tel +086-13651688596, Fax +086-021-31161589, Email luzhengmao1982@163.comAbstract: Wound healing is a complex and dynamic process, and metabolic disturbances in the microenvironment of chronic wounds and the severe symptoms they cause remain major challenges to be addressed. The inherent properties of hydrogels make them promising wound dressings. In addition, biomembrane-based nanostructures and microstructures (such as liposomes, exosomes, membrane-coated nanostructures, bacteria and algae) have significant advantages in the promotion of wound healing, including special biological activities, flexible drug loading and targeting. Therefore, biomembrane-based nanostructure- and microstructure-loaded hydrogels can compensate for their respective disadvantages and combine the advantages of both to significantly promote chronic wound healing. In this review, we outline the loading strategies, mechanisms of action and applications of different types of biomembrane-based nanostructure- and microstructure-loaded hydrogels in chronic wound healing.Keywords: biomembrane, nanostructures, microstructures, hydrogels, chronic wound healing

Published
2023

133. The melting performance blast furnace slags with high alumina content

Author

Zheng H.-Y., Zhang Y., Wang Z., Du J.-L., Jiang X., Gao Q.-J., and Shen F.-M.

Subjects
high alumina blast furnace slag, melting characteristic temperature, melting heat, differential scanning calorimetry, raman spectrum analysis, Mining engineering. Metallurgy, TN1-997
Abstract

With a view to understanding the performance of the blast furnace slag with high Al2O3 content, the effects of w(MgO)/w(Al2O3), w(CaO)/w(SiO2), and w(Al2O3) on the melting performance (melting characteristic temperature and melting heat) of the blast furnace slag with high Al2O3 content were investigated by the differential scanning calorimeter (DSC) method. Experimental results indicate that melting end temperature (Tend) for almost all the slags has no obvious change with the increase of w(MgO)/w(Al2O3), w(CaO)/w(SiO2) and w(Al2O3) of the slag will raise Tend of the slag. When (w(MgO)/w(Al2O3), R, and w(Al2O3) are high, the melting onset temperature (Tonset) of the slag increases with the increase of any variables. When w(CaO)/w(SiO2) is low, Tonset of the slag decreases with the increase of w(Al2O3). w(MgO)/w(Al2O3), w(CaO)/w(SiO2), and w(Al2O3) within the scope of this study and all these factors lead to the increase of the slag melting heat.

Published
2023
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137. Local orbital degeneracy lifting as a precursor to an orbital-selective Peierls transition

Author

Bozin, E. S., Yin, W. G., Koch, R. J., Abeykoon, M., Hor, Y. S., Zheng, H., Lei, H. C., Petrovic, C., Mitchell, J. F., and Billinge, S. J. L.

Subjects
Condensed Matter - Materials Science, Condensed Matter - Strongly Correlated Electrons
Abstract

Fundamental electronic principles underlying all transition metal compounds are the symmetry and filling of the $d$-electron orbitals and the influence of this filling on structural configurations and responses. Here we use a sensitive local structural technique, x-ray atomic pair distribution function analysis, to reveal the presence of fluctuating local-structural distortions at high temperature of one such compound, \cis . We show that this hitherto overlooked fluctuating symmetry lowering is electronic in origin and will significantly modify the energy-level spectrum and electronic and magnetic properties. The explanation is a local, fluctuating, orbital-degeneracy-lifted state. The natural extension of our result would be that this phenomenon is likely to be widespread amongst diverse classes of partially filled nominally degenerate d-electron systems, with potentially broad implications for our understanding of their properties., Comment: 10 pages 3 figures

Published
2019
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144. A geometrical interpretation of the Thomas theorem and the Efimov States

Author

Zheng, H. and Bonasera, A.

Subjects
Nuclear Theory, Physics - Atomic Physics
Abstract

Using a generalized Bohr model and the hyper-spherical formalism for a three-body system, we derive the Thomas theorem assuming a simple interaction depending on the range of the potential. We discuss the conditions for which an unbound two-body system produces a bound three-body system and derive universal energy functions. We apply our model to $^{4}$He and Triton atoms as well as to the triton nucleus. Using their scattering lengths and effective ranges, we are able to reproduce the two-body or the three-body binding energies with only one parameter fitted. Prediction for excited (Efimov) levels are also given and in particular we demonstrate that for some hyper-angles two equal minima appear which indicate a phase (shape) transition similar to the Landau's theory of phase transition. We suggest that the observed excited levels in two different experiments for the triton nucleus are indeed Efimov levels and there may be more surprises., Comment: 6 pages, 4 figures

Published
2018
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145. Nuclear probes of an out-of-equilibrium plasma at the highest compression

Author

Zhang, G., Huang, M., Bonasera, A., Ma, Y. G., Shen, B. F., Wang, H. W., Wang, W. P., Xu, J. C., Fan, G. T., Fu, H. J., Xue, H., Zheng, H., Liu, L. X., Zhang, S., Li, W. J., Cao, X. G., Deng, X. G., Li, X. Y., Liu, Y. C., Yu, Y., Zhang, Y., Fu, C. B., and Zhang, X. P.

Subjects
Physics - Plasma Physics, Nuclear Experiment
Abstract

We report the highest compression reached in laboratory plasmas using eight laser beams, E$_{laser}$$\approx$12 kJ, $\tau_{laser}$=2 ns in third harmonic on a CD$_2$ target at the ShenGuang-II Upgrade (SGII-Up) facility in Shanghai, China. We estimate the deuterium density $\rho_D$= 2.0 $\pm$ 0.9 kg/cm$^{3}$, and the average kinetic energy of the plasma ions less than 1 keV. The highest reached areal density $\Lambda \rho_{D}$=4.8 $\pm$ 1.5 g/cm$^{2}$ was obtained from the measured ratio of the sequential ternary fusion reactions (dd$\rightarrow$t+p and t+d$\rightarrow$$\alpha$+n) and the two body reaction fusions (dd$\rightarrow$$^3$He+n). At such high densities, sequential ternary and also quaternary nuclear reactions become important as well (i.e. n(14.1 MeV) + $^{12}$C $\rightarrow$ n'+$^{12}$C* etc.) resulting in a shift of the neutron (and proton) kinetic energies from their birth values. The Down Scatter Ratio (DSR-quaternary nuclear reactions) method, i.e. the ratio of the 10-12MeV neutrons divided by the total number of 14.1MeV neutrons produced, confirms the high densities reported above. The estimated lifetime of the highly compressed plasma is 52 $\pm$ 9 ps, much smaller than the lasers pulse duration., Comment: 6 pages, 5 figures, submit version

Published
2018
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146. Dedicated $\Delta$E-E detector system for searching long lived heaviest nuclei deposited in scintillators

Author

Zelga, K., Majka, Z., Płaneta, R., Sosin, Z., Wieloch, A., Adamczyk, M., Łojek, K., Barbui, M., Wuenschel, S., Hagel, K., Cao, X., Natowitz, J., Wada, R., Giuliani, G., Kim, E-J., Zheng, H., and Kowalski, S.

Subjects
Physics - Instrumentation and Detectors
Abstract

We present a dedicated experimental setup which is currently used to search for long lived super heavy elements (SHE) implanted in catcher scintillators which were irradiated by reaction products of $^{197}$Au (7.5 A.MeV) projectile and $^{232}$Th target collisions during our experiment performed at Cyclotrone Institute, Texas A$\&$M University in 2015. The built-in novel measuring apparatus consists of $\Delta$E-E detector pairs which are able to register $\alpha$ or spontaneous fission (SF) decays of heavy reaction products deposited in the scintillators. Their unique feature is that the examined scintillators are at the same time $\Delta$E part of each of $\Delta$E-E detector while E part is a silicon detector. Our apparatus is dedicated to search for SHEs which have a lifetime of a year till tens of years. Results of commissioning tests of our setup are presented., Comment: 6 pages, 3 figures, presented at Zakopane Conference on Nulear Physics 2018, submitted to Acta Physica Polonica B

Published
2018
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147. A novel experimental setup for rare events selection and its potential application to super heavy elements search

Author

Majka, Z., Planeta, R., Sosin, Z., Wieloch, A., Zelga, K., Adamczyk, M., Pelczar, K., Barbui, M., Wuenschel, S., Hagel, K., Cao, X., Kim, E-J., Natowitz, J., Wada, R., Zheng, H., Giuliani, G., and Kowalski, S.

Subjects
Physics - Instrumentation and Detectors, Nuclear Experiment
Abstract

The paper presents a novel instrumentation for rare events selection which was tested in our research of short lived super heavy elements production and detection. The instrumentation includes an active catcher multi elements system and dedicated electronics. The active catcher located in the forward hemisphere is composed of 63 scintillator detection modules. Reaction products of damped collisions between heavy ion projectiles and heavy target nuclei are implanted in the fast plastic scintillators of the active catcher modules. The acquisition system trigger delivered by logical branch of the electronics allows to record the reaction products which decay via the alpha particle emissions or spontaneous fission which take place between beam bursts. One microsecond wave form signal from FADCs contains information on heavy implanted nucleus as well as its decays., Comment: 12 pages, 5 figures, accepted for publication in Acta Physica Polonica B

Published
2018
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148. The role of the Heisenberg principle in Constrained Molecular Dynamics model

Author

Wang, K., Bonasera, A., Zheng, H., Zhang, G. Q., Ma, Y. G., and Shen, W. Q.

Subjects
Nuclear Theory
Abstract

We implement the Heisenberg principle into the Constrained Molecular Dynamics (CoMD) model with a similar approach to the Pauli principle using the one-body occupation probability $\bar{f}_i$. Results of the modified and the original model with comparisons to data are given. The binding energies and the radii of light nuclei obtained with the modified model are more consistent to the experimental data than the original one. The collision term and the density distribution are tested through a comparison to p+$^{12}$C elastic scattering data. Some simulations for fragmentation and superheavy nuclei production are also discussed., Comment: 6pages, 10 figures, submitted to PRC

Published
2018
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149. Strongly Resonating Bosons in Hot Nuclei

Author

Zhang, S., Bonasera, A., Huang, M., Zheng, H., Zhang, G., Kohley, Z., Lu, L., Ma, Y. G., and Yennello, S. J.

Subjects
Nuclear Experiment
Abstract

When two heavy ions near the Fermi energy collide, a warm and low-density region can form in which fragments appear. This region is mainly dominated by proton (p) and alpha particles. In such an environment, the alphas interact with each other, and especially through strong resonances, form complex systems such as 8Be and 12C. Our experiments show that in the reactions 70(64)Zn(64Ni)+70(64)Zn(64Ni) at E/A=35 MeV/nucleon levels of 8Be appear around relative energies Eij=0.092 MeV, 3.03 MeV as well as above 10 MeV and 100 MeV. For the 3 alpha systems, multi resonance processes give rise to excited levels of 12C. In particular, the Hoyle state at 7.654 MeV excitation energy shows a decay component through the ground state of 8Be and also shows components where two different alpha couples are at relative energies consistent with the ground state of 8Be at the same time. A component where the three alpha relative energies are consistent with the ground state of 8Be (i.e., E12=E13=E23=0.092 MeV) is also observed at the 7.458 MeV excitation energy, which was suggested as an Efimov state., Comment: 8 pages, 5 figures

Published
2018
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150. Constraining New Muonic Interactions Meditated by Axion-Like-Particles

Author

Yan, H., Sun, G. A., Peng, S. M., Guo, H., Liu, B. Q., Peng, M., and Zheng, H.

Subjects
High Energy Physics - Phenomenology, Nuclear Experiment, Nuclear Theory
Abstract

ALPs (Axion Like Particle) beyond the standard model are solutions to several important problems of modern physics. One way to detect these particles is to detect the new interactions they meditate. Many experiments have been performed to search for these new interactions in ranges from $\sim\mu$m to astrophysical range. At present, nearly all known experiments searching for the ALP-meditated long range new interactions use sources or probes containing protons, neutrons and electrons. Constraints for other fermions such as muons are scarce, though muons might be the most suspicious particles which could take part in new interactions, considering their involvement of several well known puzzles of modern physics. In this work, we discuss the possibility of explaining the anomalous magnetic moment of muons by the long range muonic new interactions mediated by ALPs. We also give a constraint for the scalar-pseudo-scalar(SP) type interaction meditated by muonic ALPs. We propose to further search the muonic SP type interaction by muon spin rotation experiments.

Published
2018

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