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537 results on '"Zhu, Hong-Tao"'

101. Chemical constituents from Piper wallichii

Author

Shi, Yan-Ni, Yang, Lian, Zhao, Jin-Hua, Shi, Yi-Ming, Qu, Yan, Zhu, Hong-Tao, Wang, Dong, Chong-Ren Yang, Xing-Cong Li, Xu, Min, and Zhang, Ying-Jun

Abstract

Fifteen known compounds including four triterpenoids (1–4), one sterol (5), one diketopiperazine alkaloid (6) and nine phenolics (7–15) were isolated from the stems of Piper wallichii. Their structures were elucidated by means of spectroscopic analysis, and acidic hydrolysis in case of the 2-oxo-3β,19α,23-trihydroxyurs-12-en-28-oic acid β-D-glucopyranosyl ester (1). The structure of compound 1 was fully assigned by 1D and 2D NMR experiments for the first time. All isolates were tested for their antibacterial, antifungal, anti-inflammatory and antiplatelet aggregation bioactivities.

Published
2015
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102. The Genus Terminalia(Combretaceae): An Ethnopharmacological, Phytochemical and Pharmacological Review

Author

Zhang, Xiao-Rui, Kaunda, Joseph Sakah, Zhu, Hong-Tao, Wang, Dong, Yang, Chong-Ren, and Zhang, Ying-Jun

Abstract

TerminaliaLinn, a genus of mostly medium or large trees in the family Combretaceae with about 250 species in the world, is distributed mainly in southern Asia, Himalayas, Madagascar, Australia, and the tropical and subtropical regions of Africa. Many species are used widely in many traditional medicinal systems, e.g., traditional Chinese medicine, Tibetan medicine, and Indian Ayurvedic medicine practices. So far, about 39 species have been phytochemically studied, which led to the identification of 368 compounds, including terpenoids, tannins, flavonoids, phenylpropanoids, simple phenolics and so on. Some of the isolates showed various bioactivities, in vitro or in vivo, such as antitumor, anti HIV-1, antifungal, antimicrobial, antimalarial, antioxidant, diarrhea and analgesic. This review covers research articles from 1934 to 2018, retrieved from SciFinder, Wikipedia, Google Scholar, Chinese Knowledge Network and Baidu Scholar by using “Terminalia” as the search term (“all fields”) with no specific time frame setting for the search. Thirty-nine important medicinal and edible Terminaliaspecies were selected and summarized on their geographical distribution, traditional uses, phytochemistry and related pharmacological activities.

Published
2019
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103. New phenolic glycosides from Phyllanthus cochinchinensis

Author

Zhao,Jian-Qiang, Wang,Yan-Ming, Lv,Jun-Jiang, Zhu,Hong-Tao, Wang,Dong, Yang,Chong-Ren, Xu,Min, and Zhang,Ying-Jun

Subjects
antimicrobial activity, phenolic glycosides, Euphorbiaceae, Phyllantus cochinchinensis, cytotoxicity
Abstract

Chemical investigation of the whole plants of Phyllanthus cochinchinensis (Euphorbiaceae) led to the isolation of three new phenolic glycosides, phyllanthuosides A-C, together with 12 known compounds. Their structures were established on the basis of extensive spectroscopic analysis and chemical methods. Among them, phyllanthuosides A and B are two of the rare phenolic glycosides, featuring with a C6-C3-C6 skeleton. The absolute configurations of phyllanthuosides A and B were established by calculated electric circular dichroism (ECD) using time dependent density functional theory (TDDFT). The isolates were also tested for their cytotoxicity and antimicrobial activity. A investigação química das plantas Phyllanthus cochinchinensis (Euphorbiaceae) levou ao isolamento de três novos glicosídeos fenólicos, filantuosídeos A-C, juntamente com 12 compostos conhecidos. Suas estruturas foram determinadas com base em extensivas análises espectroscópicas e métodos químicos. Dentre eles, filantuosídeos A e B são dois glicosídeos fenólicos raros, com um esqueleto C6-C3-C6. A configuração absoluta dos filantuosídeos A e B foi estabelecida por dicroísmo circular elétrico calculado (ECD) usando teoria do funcional da densidade e a sua abordagem dependente do tempo (TDDFT). Os compostos isolados também tiveram sua citotoxicidade e atividade antimicrobial testadas.

Published
2014

125. New triterpenoid saponins from the steaming treated roots of Panax notoginseng.

Author

Gu, Cheng-Zhen, Qiao, Yi-Jun, Wang, Dong, Zhu, Hong-Tao, Yang, Chong-Ren, Xu, Min, and Zhang, Ying-Jun

Abstract

Further phytochemical investigation of the steaming treated roots of Panax notoginseng (Araliaceae) led to the identification of two new dammarane-type triterpenoid saponins, notoginsenoside SP20 (1) and SP21 (2). In addition, a pair of new phenolic glycosides (3a and 3b) was also isolated together with two known compounds. Their structures were elucidated by HRESIMS, 1D- and 2D-NMR spectra. Compounds 1 and 2 showed no in vitro cytotoxicity against five human cancer cell lines (HL-60, SMMC-7712, A-549, MCF-9 and SW480). [ABSTRACT FROM AUTHOR]

Published
2018
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126. Plant Resources, Chemical Constituents, and Bioactivities of Tea Plants from the Genus CamelliaSection Thea

Author

Meng, Xiu-Hua, Li, Na, Zhu, Hong-Tao, Wang, Dong, Yang, Chong-Ren, and Zhang, Ying-Jun

Abstract

Tea, as one of the most popular beverages with various bioactivities, is commonly produced from the fresh leaves of two widely cultivated tea plants, Camellia sinensisand C. sinensisvar. assamica. Both plants belong to the genus Camelliasection Thea, which was considered to have 12 species and 6 varieties according to Min’s taxonomic system. Most species, except the cultivated species, are known as wild tea plants and have been exploited and utilized to produce tea by the local people of its growing areas. Thus far, six species and varieties have been phytochemically studied, leading to the identification of 398 compounds, including hydrolyzable tannins, flavan-3-ols, flavonoids, terpenoids, alkaloids, and other phenolic and related compounds. Various beneficial health effects were reported for tea and its components, involving antioxidant, antitumor, antimutagenic, antidiabetic, hypolipidemic, anti-inflammatory, antimicrobial, antiviral, antifungal, neuroprotective, hepatoprotective, etc. In this review, the geographical distribution of tea plants and the chemical constituents (1–398) reported from the genus Camelliasection Theaand some tea products (green, black, oolong, and pu-erh tea) that have ever been studied between 1970 and 2018 have been summarized, taking species as the main hint, and the main biological activities are also discussed.

Published
2019
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127. Two New Alkaloids from Fusarium tricinctumSYPF 7082, an Endophyte from the Root of Panax notoginseng

Author

Sun, Wen-Jie, Zhu, Hong-Tao, Zhang, Tian-Yuan, Zhang, Meng-Yue, Wang, Dong, Yang, Chong-Ren, Zhang, Yi-Xuan, and Zhang, Ying-Jun

Abstract

Panax notoginseng(Araliaceae) is a famous traditional Chinese medicine mainly cultivated in Yunnan and Guangxi provinces of China. Two new alkaloids, rigidiusculamide E (1) and [-(α-oxyisohexanoyl-N-methyl-leucyl)2-] (2), together with two known ones, (−)-oxysporidinone (3) and (−)-4,6′-anhydrooxysporidinone (4) were isolated from the mycelia culture of Fusarium tricinctumSYPF 7082, an endophytic fungus obtained from the healthy root of P. notoginseng. Their structures were determined on the basis of extensive spectroscopic analyses. Compounds 1–4were tested for their inhibitory effects against NO production on Murine macrophage cell line, and the new compound 2showed significant inhibitory activity on NO production with the IC50value of 18.10 ± 0.16 μM.

Published
2018
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133. Chemical constituents fromPiper wallichii

Author

Shi, Yan-Ni, primary, Yang, Lian, additional, Zhao, Jin-Hua, additional, Shi, Yi-Ming, additional, Qu, Yan, additional, Zhu, Hong-Tao, additional, Wang, Dong, additional, Yang, Chong-Ren, additional, Li, Xing-Cong, additional, Xu, Min, additional, and Zhang, Ying-Jun, additional

Published
2015
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137. Study of the whole continuous columnsyn sensor

Author

Luo Liping, Wang Youyuan, Zhu Hong-tao, and Zhou Qinglong

Subjects
Electromagnetic field, Physics, Magnetic circuit, Linear encoder, Character (mathematics), Scale (ratio), Field (physics), Electromagnetic coil, Mode (statistics), Electronic engineering, Mechanical engineering
Abstract

The whole continuous columnsyn is a new kind of digital linear displacement sensor developed on the study of traditional linear inductosyn. The sensor structure is well-knit and it has excellent electrical and mechanical character. It thoroughly eliminated the inherent end-effect of traditional linear inductosyn. This article put forward a mathematical mode of the whole continuous columnsyn which has well-knit structure and excellent electrical & mechanical character according to the electromagnetic field theory and the analysed the electromagnetic field character of columnsyn sensor, distributing of field density and columnsyn magnetic-field. It also discussed the initial phase difference caused by the installation of winding of scale and slide and confirmed the key parameters of winding design. Based on above theory, the structure and related parameters of the prototype is designed and its partial performance is validated on the prototype.

Published
2008

147. Research of Panaxspp. in Kunming Institute of Botany, CAS

Author

Qiao, Yi-Jun, Shang, Jia-Huan, Wang, Dong, Zhu, Hong-Tao, Yang, Chong-Ren, and Zhang, Ying-Jun

Abstract

Panax, a genus of the Araliaceae family, is an important herbal group in traditional Chinese medicine (TCM). Nine species and three varieties are included in the genus of Panax, in which nearly all species have been used for medicinal purposes. Among them, Panax notoginseng(Burk) F. H. Chen, Panax ginsengC. A. Meyer and Panax quinquefoliusL. are the most representative and valuable herbs world-wide, with a long history of cultivation. As the main bioactive chemical constituents, saponins with different aglycones are the major components in various Panaxspp., and their pharmacological activities are mainly reflected in the effects on blood system, cardio- and cerebro-vascular systems, nervous system, metabolism, and immune regulation. Researchers of Kunming Institute of Botany (KIB), Chinese Academy of Sciences (CAS), have put many efforts into conducting the investigations on Panaxspecies. Herein, we reviewed the research progress on Panaxspp. in KIB, CAS, over the past few decades, from the aspects of history and origin, phytochemistry and pharmacological activities.

Published
2018
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148. C-8 N-Ethyl-2-pyrrolidinone-Substituted Flavan-3-ols from the Leaves of Camellia sinensisvar. pubilimba

Author

Meng, Xiu-Hua, Zhu, Hong-Tao, Yan, Hui, Wang, Dong, Yang, Chong-Ren, and Zhang, Ying-Jun

Abstract

Camellia sinensisvar. pubilimba, one variety of the genus Camelliasect. Thea(Theaceae), has been used for producing green tea mainly by the local people of its growing areas of Guangxi province, China. Forty compounds, including eight C-8 N-ethyl-2-pyrrolidinone-substituted flavan-3-ols (1–8) and their substituted unit N-ethyl-5-hydroxy-2-pyrrolidinone (9), four flavan-3-ol monomers (10–13) and one dimer (14), nine flavonoids (15–23), three hydrolyzable tannins (24–26), two lignans (27–28), 11 simple phenolics (29–39), and caffeine (40), were first isolated and identified from the leaves. Their structures were determined by detailed spectroscopic analysis and comparison with the literature data and authentic samples. Both 1and 4were obtained as a mixture of the N-ethyl-2-pyrrolidinone C-5 enantiomers (1aand 1band 4aand 4b), respectively, while the resolution of another three pairs of enantiomers (2and 3, 5and 6, and 7and 8) was achieved. Among them, 1bis a new compound whose NMR data together with its enantiomer (1a) were reported for the first time, while 2and 3are two new natural products. Most of the isolates exhibited significant antioxidant activities, stronger than ascorbic acid and trolox, while parts of the isolates, particularly C-8 N-ethyl-2-pyrrolidinone-substituted flavan-3-ols, showed obvious inhibitory effects on acetylcholinesterase (AChE). The results indicated that C. sinensisvar. pubilimbais a valuable plant resource for tea production.

Published
2018
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