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1,239 results on '"van de Heyning, P."'

102. Effect of Training on Vascular Function and Repair in Heart Failure With Preserved Ejection Fraction

Author

Gevaert, Andreas B., Böhm, Birgit, Hartmann, Haley, Goovaerts, Inge, Stoop, Tibor, Van De Heyning, Caroline M., Beckers, Paul J., Baldassarri, Flavia, Mueller, Stephan, Oberhoffer, Renate, Duvinage, André, Haykowsky, Mark J., Wisløff, Ulrik, Adams, Volker, Pieske, Burkert, Halle, Martin, and Van Craenenbroeck, Emeline M.

Abstract

Exercise training improves peak oxygen uptake (V.O2peak) in heart failure with preserved ejection fraction (HFpEF). Multiple adaptations have been addressed, but the role of circulating endothelium-repairing cells and vascular function have not been well defined.

Published
2023
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103. Evaluation of Cognitive Functioning Before and After Cochlear Implantation in Adults Aged 55 Years and Older at Risk for Mild Cognitive Impairment

Author

Andries, Ellen, Bosmans, Joyce, Engelborghs, Sebastiaan, Cras, Patrick, Vanderveken, Olivier M., Lammers, Marc J. W., Van de Heyning, Paul H., Van Rompaey, Vincent, and Mertens, Griet

Abstract

IMPORTANCE: Given the rapidly rising dementia incidence, management of modifiable risk factors, such as hearing loss, is vital. Multiple studies have demonstrated an improvement of cognitive functioning in older adults with severe hearing loss after cochlear implantation; however, few of these studies, to the authors’ knowledge, specifically analyzed participants achieving poor cognitive results preoperatively. OBJECTIVE: To evaluate the cognitive functioning of older adults with severe hearing loss at risk for mild cognitive impairment (MCI) before and after cochlear implantation. DESIGN, SETTING, AND PARTICIPANTS: This prospective, longitudinal cohort study performed at a single center reports data obtained over a 6-year period (April 2015 to September 2021) of an ongoing prospective, longitudinal cohort study on cochlear implant outcomes in older adults. A consecutive sample of older adults with severe hearing loss eligible for cochlear implantation was included. All participants obtained a Repeatable Battery for the Assessment of Neuropsychological Status for hearing-impaired patients (RBANS-H) total score indicative of MCI preoperatively. Participants were assessed before cochlear implant activation and 12 months after cochlear implant activation. INTERVENTION: The intervention consisted of cochlear implantation. MAIN OUTCOME AND MEASURE: The primary outcome measure was cognition, measured by the RBANS-H. RESULTS: A total of 21 older adult cochlear implant candidates were included in the analysis (mean [SD] age, 72 [9] years; 13 [62%] men). Cochlear implantation was associated with an improvement of overall cognitive functioning 12 months after activation (median [IQR] percentile, 5 [2-8] vs 12 [7-19]; difference, 7 [95% CI, 2-12]). Eight participants (38%) surpassed the MCI cutoff (16th percentile) postoperatively, while the overall median cognitive score remained under this cutoff. In addition, participants’ speech recognition in noise improved, with a lower score indicating improvement (mean [SD] score, +17.16 [5.45] vs +5.67 [6.3]; difference, −11.49 [95% CI, −14.26 to −8.72]), after cochlear implant activation. Improvement of speech recognition in noise was positively associated with improvement in cognitive functioning (rs, −0.48 [95% CI, −0.69 to −0.19]). Years of education, sex, RBANS-H version, and symptoms of depression and anxiety were not related to the evolution in RBANS-H scores. CONCLUSIONS AND RELEVANCE: In this prospective, longitudinal cohort study, cognitive functioning and speech perception in noise showed a clinically meaningful improvement 12 months after cochlear implant activation in older adults with severe hearing loss at risk for MCI, suggesting that cochlear implantation is not contraindicated in cochlear implant candidates with cognitive decline and should be considered after multidisciplinary evaluation.

Published
2023
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104. Tinnitus and tinnitus disorder: Theoretical and operational definitions (an international multidisciplinary proposal)

Author

De Ridder, D. Schlee, W. Vanneste, S. Londero, A. Weisz, N. Kleinjung, T. Shekhawat, G.S. Elgoyhen, A.B. Song, J.-J. Andersson, G. Adhia, D. de Azevedo, A.A. Baguley, D.M. Biesinger, E. Binetti, A.C. Del Bo, L. Cederroth, C.R. Cima, R. Eggermont, J.J. Figueiredo, R. Fuller, T.E. Gallus, S. Gilles, A. Hall, D.A. Van de Heyning, P. Hoare, D.J. Khedr, E.M. Kikidis, D. Kleinstaeuber, M. Kreuzer, P.M. Lai, J.-T. Lainez, J.M. Landgrebe, M. Li, L.P.-H. Lim, H.H. Liu, T.-C. Lopez-Escamez, J.A. Mazurek, B. Moller, A.R. Neff, P. Pantev, C. Park, S.N. Piccirillo, J.F. Poeppl, T.B. Rauschecker, J.P. Salvi, R. Sanchez, T.G. Schecklmann, M. Schiller, A. Searchfield, G.D. Tyler, R. Vielsmeier, V. Vlaeyen, J.W.S. Zhang, J. Zheng, Y. de Nora, M. Langguth, B.

Subjects
otorhinolaryngologic diseases
Abstract

As for hypertension, chronic pain, epilepsy and other disorders with particular symptoms, a commonly accepted and unambiguous definition provides a common ground for researchers and clinicians to study and treat the problem. The WHO's ICD11 definition only mentions tinnitus as a nonspecific symptom of a hearing disorder, but not as a clinical entity in its own right, and the American Psychiatric Association's DSM-V doesn't mention tinnitus at all. Here we propose that the tinnitus without and with associated suffering should be differentiated by distinct terms: “Tinnitus” for the former and “Tinnitus Disorder” for the latter. The proposed definition then becomes “Tinnitus is the conscious awareness of a tonal or composite noise for which there is no identifiable corresponding external acoustic source, which becomes Tinnitus Disorder “when associated with emotional distress, cognitive dysfunction, and/or autonomic arousal, leading to behavioural changes and functional disability.”. In other words “Tinnitus” describes the auditory or sensory component, whereas “Tinnitus Disorder” reflects the auditory component and the associated suffering. Whereas acute tinnitus may be a symptom secondary to a trauma or disease, chronic tinnitus may be considered a primary disorder in its own right. If adopted, this will advance the recognition of tinnitus disorder as a primary health condition in its own right. The capacity to measure the incidence, prevalence, and impact will help in identification of human, financial, and educational needs required to address acute tinnitus as a symptom but chronic tinnitus as a disorder. © 2021 Elsevier B.V.

Published
2021

105. Diagnostic accuracy and usability of the EMBalance decision support system for vestibular disorders in primary care: proof of concept randomised controlled study results

Author

Bamiou, D.-E. Kikidis, D. Bibas, T. Koohi, N. Macdonald, N. Maurer, C. Wuyts, F.L. Ihtijarevic, B. Celis, L. Mucci, V. Maes, L. Van Rompaey, V. Van de Heyning, P. Nazareth, I. Exarchos, T.P. Fotiadis, D. Koutsouris, D. Luxon, L.M.

Subjects
carbohydrates (lipids), stomatognathic diseases, animal diseases, digestive system, digestive system diseases
Abstract

Background: Dizziness and imbalance are common symptoms that are often inadequately diagnosed or managed, due to a lack of dedicated specialists. Decision Support Systems (DSS) may support first-line physicians to diagnose and manage these patients based on personalised data. Aim: To examine the diagnostic accuracy and application of the EMBalance DSS for diagnosis and management of common vestibular disorders in primary care. Methods: Patients with persistent dizziness were recruited from primary care in Germany, Greece, Belgium and the UK and randomised to primary care clinicians assessing the patients with (+ DSS) versus assessment without (− DSS) the EMBalance DSS. Subsequently, specialists in neuro-otology/audiovestibular medicine performed clinical evaluation of each patient in a blinded way to provide the “gold standard” against which the + DSS, − DSS and the DSS as a standalone tool (i.e. without the final decision made by the clinician) were validated. Results: One hundred ninety-four participants (age range 25–85, mean = 57.7, SD = 16.7 years) were assigned to the + DSS (N = 100) and to the − DSS group (N = 94). The diagnosis suggested by the + DSS primary care physician agreed with the expert diagnosis in 54%, compared to 41.5% of cases in the − DSS group (odds ratio 1.35). Similar positive trends were observed for management and further referral in the + DSS vs. the − DSS group. The standalone DSS had better diagnostic and management accuracy than the + DSS group. Conclusion: There were trends for improved vestibular diagnosis and management when using the EMBalance DSS. The tool requires further development to improve its diagnostic accuracy, but holds promise for timely and effective diagnosis and management of dizzy patients in primary care. Trial registration number: NCT02704819 (clinicaltrials.gov). © 2021, The Author(s).

Published
2021

106. Occupational Noise, Smoking, and a High Body Mass Index are Risk Factors for Age-related Hearing Impairment and Moderate Alcohol Consumption is Protective: A European Population-based Multicenter Study

Author

Fransen, Erik, Topsakal, Vedat, Hendrickx, Jan-Jaap, Van Laer, Lut, Huyghe, Jeroen R., Van Eyken, Els, Lemkens, Nele, Hannula, Samuli, Mäki-Torkko, Elina, Jensen, Mona, Demeester, Kelly, Tropitzsch, Anke, Bonaconsa, Amanda, Mazzoli, Manuela, Espeso, Angeles, Verbruggen, Katia, Huyghe, Joke, Huygen, Patrick L. M., Kunst, Sylvia, Manninen, Minna, Diaz-Lacava, Amalia, Steffens, Michael, Wienker, Thomas F., Pyykkö, Ilmari, Cremers, Cor W. R. J., Kremer, Hannie, Dhooge, Ingeborg, Stephens, Dafydd, Orzan, Eva, Pfister, Markus, Bille, Michael, Parving, Agnete, Sorri, Martti, Van de Heyning, Paul, and Van Camp, Guy

Published
2008
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109. Evolution of vocal fold nodules from childhood to adolescence

Author

De Bodt, M.S., Ketelslagers, K., Peeters, T., Wuyts, F.L., Mertens, F., Pattyn, J., Heylen, L., Peeters, A., Boudewyns, A., and Van de Heyning, P.

Subjects
Care and treatment, Research, Vocal cords -- Research, Voice disorders -- Research -- Care and treatment
Abstract

Summary: Bilateral (quasi) symmetrical lesions of the anterior third of the vocal folds, commonly called vocal fold nodules (VFNs) are the most frequent vocal fold lesions in childhood caused by [...]

Published
2007

110. Consensus for tinnitus patient assessment and treatment outcome measurement: Tinnitus Research Initiative meeting, Regensburg, July 2006

Author

Langguth, B., Goodey, R., Azevedo, A., Bjorne, A., Cacace, A., Crocetti, A., Del Bo, L., De Ridder, D., Diges, I., Elbert, T., Flor, H., Herraiz, C., Ganz Sanchez, T., Eichhammer, P., Figueiredo, R., Hajak, G., Kleinjung, T., Landgrebe, M., Londero, A., Lainez, M.J.A., Mazzoli, M., Meikle, M.B., Melcher, J., Rauschecker, J.P., Sand, P.G., Struve, M., Van de Heyning, P., Van Dijk, P., and Vergara, R.

Published
2007
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129. Acute Myocarditis Associated With Desmosomal Gene Variants

Author

Ammirati, Enrico, Raimondi, Francesca, Piriou, Nicolas, Sardo Infirri, Loren, Mohiddin, Saidi A., Mazzanti, Andrea, Shenoy, Chetan, Cavallari, Ugo A., Imazio, Massimo, Aquaro, Giovanni Donato, Olivotto, Iacopo, Pedrotti, Patrizia, Sekhri, Neha, Van de Heyning, Caroline M., Broeckx, Glenn, Peretto, Giovanni, Guttmann, Oliver, Dellegrottaglie, Santo, Scatteia, Alessandra, Gentile, Piero, Merlo, Marco, Goldberg, Randal I., Reyentovich, Alex, Sciamanna, Christopher, Klaassen, Sabine, Poller, Wolfgang, Trankle, Cory R., Abbate, Antonio, Keren, Andre, Horowitz-Cederboim, Smadar, Cadrin-Tourigny, Julia, Tadros, Rafik, Annoni, Giuseppe A., Bonoldi, Emanuela, Toquet, Claire, Marteau, Lara, Probst, Vincent, Trochu, Jean Noël, Kissopoulou, Antheia, Grosu, Aurelia, Kukavica, Deni, Trancuccio, Alessandro, Gil, Cristina, Tini, Giacomo, Pedrazzini, Matteo, Torchio, Margherita, Sinagra, Gianfranco, Gimeno, Juan Ramón, Bernasconi, Davide, Valsecchi, Maria Grazia, Klingel, Karin, Adler, Eric D., Camici, Paolo G., and Cooper, Leslie T.

Abstract

The risk of adverse cardiovascular events in patients with acute myocarditis (AM) and desmosomal gene variants (DGV) remains unknown.

Published
2022
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131. Contribution of the N-acetyltransferase 2 polymorphism NAT2*6A to age-related hearing impairment

Author

Van Eyken, E, Van Camp, G, Fransen, E, Topsakal, V, Hendrickx, J J, Demeester, K, Van de Heyning, P, Mäki-Torkko, E, Hannula, S, Sorri, M, Jensen, M, Parving, A, Bille, M, Baur, M, Pfister, M, Bonaconsa, A, Mazzoli, M, Orzan, E, Espeso, A, Stephens, D, Verbruggen, K, Huyghe, J, Dhooge, I, Huygen, P, Kremer, H, Cremers, C W R J, Kunst, S, Manninen, M, Pyykkö, I, Lacava, A, Steffens, M, Wienker, T F, and Van Laer, L

Published
2007

135. A genotype-phenotype correlation for GJB2 (connexin 26) deafness

Author

Cryns, K, Orzan, E, Murgia, A, Huygen, P L M, Moreno, F, del Castillo, I, Chamberlin, G Parker, Azaiez, H, Prasad, S, Cucci, R A, Leonardi, E, Snoeckx, R L, Govaerts, P J, Van de Heyning, P H, Van de Heyning, C M, Smith, R J H, and Van Camp, G

Published
2004

140. Evolution of Type D Personality Traits After Cochlear Implantation in Severely Hearing Impaired Adults 55 Years and Older: An Exploratory Prospective, Longitudinal, Controlled, Multicenter Study

Author

Andries, Ellen, Bieńkowska, Katarzyna, Świerniak, Weronika, Skarżyński, Piotr Henryk, Skarżyński, Henryk, Calvino, Miryam, Cuadrado, Isabel Sanchez, Muñoz, Elena, Gavilán, Javier, Lassaletta, Luis, Tavora-Vieira, Dayse, Acharya, Aanand, Killan, Catherine, Ridgwell, Jillian, Raine, Christopher, Van de Heyning, Paul, Van Rompaey, Vincent, and Mertens, Griet

Published
2022
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147. Evaluating the Revised Work Rehabilitation Questionnaire in Cochlear Implant Users Cochlear Implant Outcome Assessment Based on the International Classification of Functioning, Disability, and Health (ICF)

Author

Andries, Ellen, Lorens, Artur, Skarżyński, Piotr Henryk, SkarZynski, Henryk, Calvino, Miryam, Gavilan, Javier, Lassaletta, Luis, Tavora-Vieira, Dayse, Acharya, Aanand, Kurz, Anja, Hagen, Rudolf, Anderson, Ilona, Amann, Edda, Van de Heyning, Paul, Van Rompaey, Vincent, and Mertens, Griet

Published
2022
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