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363 results on '"A. N. Denisenko"'

151. ChemInform Abstract: Conversions by Dimethyldioxirane of 1-Alkylbenzotriazoles into Their N-Oxides and of 2-Alkylbenzotriazoles into 2-Alkyl-trans-4,5,6,7-diepoxy-4,5,6,7-tetrahydrobenzotriazoles

Author

Alan R. Katritzky, Rexiat Maimait, Sergey N. Denisenko, Novruz G. Akhmedov, and Peter J. Steel

Subjects
chemistry.chemical_classification, chemistry.chemical_compound, Chemistry, Triazole derivatives, Organic chemistry, General Medicine, Dimethyldioxirane, Alkyl
Abstract

Dimethyldioxirane converted 1-alkylbenzotriazoles 4 to the corresponding 3-alkylbenzotriazole 1-oxides 5 in good yields, but transformed 2-alkylbenzotriazoles 12 into 2-alkyl-trans-4,5,6,7-diepoxy-4,5,6,7-tetrahydrobenzotriazoles 13.

Published
2010
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152. Asymmetric nitrogen. 76. Quantum chemical study of geometry and configurational stability of ketenimines

Author

S. N. Denisenko, A. V. Kachanov, R. G. Kostyanovskii, and G. V. Shustov

Subjects
Quantum chemical, chemistry.chemical_compound, chemistry, Automotive Engineering, Atom, chemistry.chemical_element, MNDO, Configurational stability, Geometry, General Chemistry, Acceptor, Nitrogen, Ketenimine
Abstract

MNDO calculations were carried out of the ground and transitional states of the planar inversion of the N atom for ketenimines containing σ (Me, NH2, OH, OMe, and F) and π (CH = O) acceptor N substituents as well as for C-amino- and C-formylketenimines. Configurationally stable N-amino-, N-alkoxy-, and N-fluoroketenimines (inversion barriers ∼27–45 kcal/mole) are of interest for further experimental stereochemical studies. The geometry of the ketenimine fragment is determined in general bynN-πCC* conjugation. Other orbital and Coulombic interactions affect C- and N-substituent orientation relative to this fragment.

Published
1992
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153. In vivo endoscopic OCT imaging of precancer and cancer states of human mucosa

Author

A. N. Denisenko, Felix I. Feldchtein, A. V. Shakhov, Natalia D. Gladkova, Valentin M. Gelikonov, Natalia M. Shakhova, Roman V. Kuranov, Ludmila B. Snopova, Yu. P. Chumakov, Alexander M. Sergeev, V. V. Pochinko, I. A. Kuznetzova, Grigory V. Gelikonov, and Olga Streltzova

Subjects
Larynx, Pathology, medicine.medical_specialty, Urinary bladder, medicine.diagnostic_test, business.industry, Stomach, Cancer, medicine.disease, Atomic and Molecular Physics, and Optics, medicine.anatomical_structure, Optics, Biopsy, medicine, Sampling (medicine), Esophagus, business, Preclinical imaging
Abstract

First results of endoscopic applications of optical coherence tomography for in vivo studies of human mucosa in respiratory, gastrointestinal, urinary and genital tracts are presented. A novel endoscopic OCT (EOCT) system has been created that is based on the integration of a sampling arm of an all-optical-fiber interferometer into standard endoscopic devices using their biopsy channel to transmit low-coherence radiation to investigated tissue. We have studied mucous membranes of esophagus, larynx, stomach, urinary bladder, uterine cervix and body as typical localization for carcinomatous processes. Images of tumor tissues versus healthy tissues have been recorded and analyzed. Violations of well-defined stratified healthy mucosa structure in cancered tissue are distinctly seen by EOCT, thus making this technique promising for early diagnosis of tumors and precise guiding of excisional biopsy.

Published
2009

154. 13C NMR spectra of polycyclic diaziridines

Author

G. V. Shustov, R. G. Kostyanovskii, Gerd Kaupp, and S. N. Denisenko

Subjects
Quantum chemical, Crystallography, Valence (chemistry), Carbon-13 NMR satellite, Computational chemistry, Chemistry, Chemical shift, Significant difference, General Chemistry, Carbon-13 NMR, Spectral line
Abstract

A significant difference between experimental13C NMR chemical shifts and those predicted from the13C NMR/IR databank was found for bi- and tricyclic diaziridines. Quantum chemical (AMI) and molecular-mechanical (MMX) calculations showed that the relative chemical shift of the nodal C atom is dependent mainly on deformations of the C-C-C valence angle at this atom.

Published
1991
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155. Stimulation of actin synthesis in phalloidin-treated cells

Author

A.S. Serpinskaya, Oleg N. Denisenko, Vladimir I. Gelfand, and Alexander D. Bershadsky

Subjects
Phalloidine, Ratón, Phalloidin, Biophysics, Gene Expression, Stimulation, macromolecular substances, In Vitro Techniques, Microfilament, Biochemistry, Mouse fibroblast, Mice, chemistry.chemical_compound, Tubulin, Structural Biology, Genetics, Animals, RNA, Messenger, Northern blot, Molecular Biology, Cells, Cultured, Cytoskeleton, Actin, biology, Embryo, Cell Biology, Feedback control, Blotting, Northern, Actin synthesis, biology.organism_classification, Actina, Molecular biology, Actins, Cell biology, Actin Cytoskeleton, chemistry, Scrape loading
Abstract

We used the technique of scrape loading to introduce phalloidin into mouse embryo fibroblasts in mass culture. Phalloidin almost completely destroyed actin microfilament bundles, but the amount of polymerized cytoskeleton-associated actin was increased approximately two-fold and the amount of monomeric (Triton X-100 extractable) actin was significantly reduced. The major result of the present study is that the rate of actin synthesis in the phalloidin-treated cells was 2–3 times higher than in the control cells. Northern blot and translation in a cell-free system from rabbit reticulocytes showed that the actin mRNA level significantly increased as a result of phalloidin treatment.

Published
1990
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156. Orbital interactions in diaziridines

Author

S. N. Denisenko, A. J. Bittner, Gerd Kaupp, and Paul Rademacher

Subjects
Inorganic Chemistry, Crystallography, X-ray photoelectron spectroscopy, Bicyclic molecule, Chemistry, Stereochemistry, Photoemission spectroscopy, Organic Chemistry, Molecule, Ionization energy, Ultraviolet radiation, Spectroscopy, Analytical Chemistry
Abstract

The energy differences Δϵ of the n-orbitals n+ and n− (HOMO and HOMO-1) in the tricyclic and bicyclic diaziridines 1, 2, 5 and 6 have been determined by photoelectron spectroscopy and AM1 calculations. It has been found that Δϵ is determined mainly by the pyramidality of the nitrogen atoms. Although the interactions with the Walsh orbital ωA are considerable, they are of minor importance for the MO separation.

Published
1990
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157. [Optical coherence tomography in surgical treatment of esophageal cancer]

Author

E V, Zagaĭnova, V E, Zagaĭnov, N D, Gladkova, A N, Denisenko, V V, Slugarev, G V, Gelikonov, and V A, Kamenskiĭ

Subjects
Radiography, Esophageal Neoplasms, Humans, Neoplasm Invasiveness, Esophagoscopy, Tomography, Optical Coherence
Abstract

The authors present an analysis of possibilities of optical coherence tomography in preoperative determination of the proximal interface of the tumor. Under investigation there were 24 patients (14 of them with squamous cell carcinoma and 10 with adenocarcinoma), with localization of the process not more than 5 cm the from z-line.

Published
2007

158. Stereospecific synthesis of bicyclic diaziridines: 4a-chloro-; 4e,6a- and 4a,6e-dichloro-5-methoxycarbonyl-1,6-diazabicyclo[3.1.0]hexanes

Author

Paul Rademacher, Remir G. Kostyanovsky, and Sergey N. Denisenko

Subjects
chemistry.chemical_compound, Stereospecificity, Diaziridine, Bicyclic molecule, Chemistry, Stereochemistry, Substituent, Chlorine, chemistry.chemical_element, General Chemistry, Isomerization, Amination
Abstract

Amination of 2-methoxycarbonyl-3-chloro-1-pyrroline 1 with H2NOSO3H occurs predominantly from the anti side with respect to chlorine to afford the bicyclic diaziridine 2 with axial orientation of the 4-chloro substituent. Chlorination of 2 takes place exclusively in the 6-endo position to give 3a. 4,6-Dichlorodiaziridine is transformed from chair 3a into boat 3b as a result of endo-exo isomerization.

Published
1998
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159. [Dynamic health state control in personnel of the Radiology Department of Bryansk Regional Oncological Dispensary]

Author

V N, Antropov, O N, Denisenko, R V, Stavitskiĭ, D P, Lobov, V N, Vasil'ev, L N, Lebedev, and S G, Mikheenko

Subjects
Chernobyl Nuclear Accident, Radiation Monitoring, Occupational Exposure, Workforce, Humans, Longitudinal Studies, Medical Oncology, Radioactive Hazard Release, Radiology, Ukraine, Occupational Health, Power Plants, Russia
Abstract

The health state of personnel of the Radiology Department of Bryansk Regional Oncological Dispensary before and after Chernobyl Nuclear Disaster is analyzed using an automated classifying system. The system operation is based on analysis of peripheral blood count.

Published
2006

160. Optical coherence tomography in guided surgery of GI cancer

Author

Irina S. Kutis, Vladimir E. Zagaynov, Elena V. Zagaynova, Alexander I. Abelevich, Felix I. Feldchtein, Ludmila B. Snopova, A. N. Denisenko, and Natalia D. Gladkova

Subjects
medicine.medical_specialty, genetic structures, medicine.diagnostic_test, business.industry, Colorectal cancer, Cancer, Rectum, Esophageal cancer, medicine.disease, eye diseases, Surgery, Endoscopy, medicine.anatomical_structure, Rectal Adenocarcinoma, Carcinoma, Medicine, sense organs, Esophagus, business
Abstract

Optical Coherence Tomography (OCT) is a new high spatial resolution, real-time optical imaging modality, known from prior pilot studies for its high sensitivity to invasive cancer. We reported our results in an OCT feasibility study for accurate determination of the proximal border for esophageal carcinoma and the distal border for rectal carcinoma. The OCT study enrolled 19 patients with rectal adenocarcinoma and 24 patients with distal esophageal carcinoma (14 squamous cell carcinomas, 10 adenocarcinomas). During pre-surgery planning endoscopy we performed in vivo OCT imaging of the tumor border at four dial clock axes (12, 3, 6 and 9 o’clock). The OCT border then was marked by an electrocoagulator, or by a methylene blue tattoo. A cold biopsy (from the esophagus) was performed at visual and OCT borders and compared with visual and OCT readings. 27 post-surgery excised specimens were analyzed. OCT borders matched the histopathology in 94% cases in the rectum and 83.3% in the esophagus. In the cases of a mismatch between the OCT and histology borders, a deep tumor invasion occurred in the muscle layer (esophagus, rectum). Because of its high sensitivity to mucosal cancer, OCT can be used for pre-surgery planning and surgery guidance of the proximal border for esophageal carcinoma and the distal border for rectal carcinoma. However, deep invasion in the rectum or esophageal wall has to be controlled by alternative diagnostic modalities.

Published
2005
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161. The chemical inventory system of the center for heterocyclic compounds, University of Florida

Author

Ruslan Petrukhin, Sergey N. Denisenko, Alan R. Katritzky, and Douglas B. Tatham

Subjects
Computational Theory and Mathematics, Chemical engineering, Database, Chemistry, Environmental science, Center (algebra and category theory), General Chemistry, General Medicine, Inventory system, computer.software_genre, computer, Computer Science Applications, Information Systems
Abstract

A system suitable for tracking the amounts and locations of ca. 10 000 chemicals is described.

Published
2002

162. 1H NMR spectroscopic characterization of solutions of Sepia melanin, Sepia melanin free acid and human hair melanin

Author

Olga V. Denisko, Alan R. Katritzky, Sergey N. Denisenko, and Novruz G. Akhmedov

Subjects
Melanins, Magnetic Resonance Spectroscopy, Free acid, Chemistry, Clinical Biochemistry, Cell Biology, Plant Science, Hydrogen Peroxide, Melanin, Solutions, Nuclear magnetic resonance, Mollusca, Proton NMR, Animals, Humans, Sepia, Deuterium Oxide, Protons, Agronomy and Crop Science, Developmental Biology, Nuclear chemistry, Hair
Abstract

A 1 H nuclear magnetic resonance study of Sepia melanin, Sepia melanin free acid (Sepia MFA) and human hair melanin was carried out in deuterium oxide solution at pH 10-11. The empirical formula of Sepia MFA was calculated and used to estimate the number of protons in the aromatic region of the Sepia MFA polymeric chain and to suggest a possible monomeric unit profile.

Published
2002

163. QSAR correlations of the algistatic activity of 5-amino-1-aryl-1H-tetrazoles

Author

T Schelenz, Ritu Jain, Sergey N. Denisenko, Alan R. Katritzky, and Ruslan Petrukhin

Subjects
Quantitative structure–activity relationship, Chemistry, Stereochemistry, Aryl, Eukaryota, Quantitative Structure-Activity Relationship, Tetrazoles, Bioengineering, General Medicine, chemistry.chemical_compound, Computational chemistry, Drug Discovery, Linear Models, Molecular Medicine, Parameter equation
Abstract

The algistatic activity of 20 substituted 5-amino-1-aryl-1H-tetrazoles was correlated with the second order Kier and Hall index, the XY shadow on the XY rectangle and the total hybridization component of the molecular dipole by the CODESSA program in a three parameter equation with r2 = 0.9330.

Published
2001

164. ChemInform Abstract: Convenient One-Pot Syntheses of Pyrazoles from Imines, a Vilsmeier Type Reagent and Hydrazine

Author

Anna Denisenko, Sergey N. Denisenko, Alan R. Katritzky, and Michael Arend

Subjects
Steric effects, chemistry.chemical_compound, chemistry, Reagent, Hydrazine, Regioselectivity, Organic chemistry, General Medicine, Tautomer, Tetrahydrofuran
Abstract

A simple one-pot procedure for the regioselective synthesis of pyrazoles from readily available starting materials is described. Vilsmeier type reagent 1 reacts with imines 10 (via the corresponding tautomeric secondary enamines) in tetrahydrofuran to give enaminoimine hydrochlorides 11. Nonsymmetrical imines generally react preferentially with 1 at the sterically less hindered α-position. The enaminoimine hydrochlorides 11 are transformed in situ to the corresponding pyrazoles 12 in moderate to high yields by the addition of hydrazine.

Published
2001
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165. 13C NMR spectra of tricyclic diaziridines and their data-base forecasts

Author

G. Kaupp and S. N. Denisenko

Subjects
Bicyclic molecule, Diaziridine, Chemistry, Stereochemistry, Chemical shift, General Chemistry, Nuclear magnetic resonance spectroscopy, Carbon-13 NMR, Energy minimization, Spectral line, chemistry.chemical_compound, Molecular geometry, Computational chemistry, General Materials Science
Abstract

The 13C NMR data for tricyclic and bicyclic diaziridines with condensed five- and six-membered rings are interpreted and compared with the forecast of the C13-NMR/IR data-base (successor: SPECINFO data-base). There are large differences in chemical shifts and large deviations in the forecasts. Bond angles from semi-empirical AM1 calculations with geometry optimization correlate with the observed shifts. Similar behaviour is found for some known bicyclic diaziridines, and this is also discussed together with some known 13C shift variations in other diaziridines and bicyclic hydrocarbons. It is suggested that the widely used data-base should include subset search facilities in order to minimize the risk of misassignments. This would allow specific effects, such as those of bond angles in cyclic compounds, to be taken into consideration.

Published
1992
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167. X-band amplifier of gigawatt pulse power

Author

V. V. Yastrebov, A. N. Denisenko, E. B. Abubakirov, D. Flechtner, N. F. Kovalev, E. I. Soluyanov, M. I. Petelin, N. G. Kolganov, A. V. Savelyev, and M. I. Fuchs

Subjects
Physics, Optics, business.industry, Amplifier, Harmonics, Bandwidth (signal processing), X band, Cathode ray, Pulsed power, Radiation, business, Cherenkov radiation
Abstract

In X-band Cherenkov amplifier driven by 0.8 MeV 6 kA electron beam, the gigawatt power in pulses with duration 70 ns is achieved. The coherence of output radiation is provided by division of the oversized interaction space on separate sections coupled with the electron beam only. The high gain of 47 dB (and accordingly narrow 1% bandwidth) are obtained with the regenerative regime of operation of BWA-modulator used as a pre-amplifier.

Published
1999
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168. Determination of the mass of theWboson using the D∅ detector at the Fermilab Tevatron

Author

C. S. Mishra, G. Guglielmo, P. Gartung, Vasken Hagopian, M.K. Fatyga, W. Y. Chen, Gilvan Alves, H. Weerts, C. Murphy, R. K. Shivpuri, George R. Kalbfleisch, Lev Dudko, R. Astur, V. S. Narasimham, M. Tartaglia, T. Heuring, K. M. Mauritz, S. Lami, D. Casey, P.F. Ermolov, A. A. Mayorov, N.V. Mokhov, Kaushik De, M. K. Fatyga, G. E. Forden, A. P. Heinson, S. P. Denisov, P. Grudberg, V. S. Burtovoi, M. R. Krishnaswamy, Rajendran Raja, J. Snow, C. Klopfenstein, S. Youssef, S. Choi, C. Cretsinger, N. Parua, R. E. Hall, A. Sanchez-Hernandez, Robert Kehoe, B. Baldin, J. Balderston, Y. Ducros, F. Hsieh, Victor Daniel Elvira, T. Fahland, A. Jonckheere, A. R. Clark, S. Grünendahl, A. Para, M. Strovink, Stephan Linn, E. James, J. L. González Solís, Z. Casilum, Matthew Jones, Brad Abbott, R. L. Lander, D. Lincoln, Eunil Won, M. Bhattacharjee, E. Flattum, R. Snihur, J. M. Guida, D. Hedin, R. J. Madaras, P. Bloom, J. A. Wightman, S. Krzywdzinski, N. Oshima, Sergey Chekulaev, Daria Zieminska, R. Hirosky, N. I. Bojko, D. Buchholz, N. Varelas, R. D. Schamberger, V. I. Kochetkov, Q. Z. Li-Demarteau, B. Gibbard, P. Tamburello, J. S. Hoftun, K. Davis, J. N. Butler, Heng Xu, P. D. Grannis, L. Magaña-Mendoza, S. Feher, S. M. Chang, H. Piekarz, Pushpalatha C Bhat, A. Zylberstejn, K. Del Signore, E. G. Zverev, Anna Goussiou, Randy Ruchti, Ting Hu, V. A. Bezzubov, S. C. Loken, A. L. Spadafora, K. Gounder, J. Sculli, R. Hernández-Montoya, F. Stichelbaut, H. Greenlee, Alexander Belyaev, P. Hanlet, C. L. Kim, Haifeng Li, J. P. Negret, R. P. Smith, A. Zieminski, Gregory R Snow, V. Oguri, Michael Shupe, Hiroaki Aihara, S. Fuess, G. Finocchiaro, N. Sotnikova, J. Krane, H. Lan, B. Lauer, M. A.C. Cummings, B. Hoeneisen, H. L. Melanson, P. Z. Quintas, A. Bross, Lee Sawyer, D. Stewart, S. N. Gurzhiev, P. I. Goncharov, Stephen Wimpenny, P. M. Tuts, R. L. McCarthy, M. Merkin, M. L. Kelly, Howard Gordon, Heriberto Castilla-Valdez, G. P. Grim, Gordon Watts, V. Sirotenko, R. W. Stephens, Meenakshi Narain, M. L. Stevenson, T. Marshall, Gervasio Gomez, Serban Protopopescu, S. Y. Jun, T. L.T. Thomas, B. May, K. C. Frame, Andrew White, O. V. Eroshin, O. Ramirez, Dhiman Chakraborty, Phillip Gutierrez, N. Denisenko, M. Chung, D. P. Stoker, M. H.G. Souza, A. V. Kotwal, Harrison Prosper, S. Reucroft, C. Yoshikawa, Darien Wood, T. McMahon, Y. E. Gutnikov, J. Warchol, Y. M. Park, S.A. Kahn, T. Huehn, D. Fein, Peter Nemethy, H. D. Wahl, T. G. Trippe, G. Eppley, P. Yepes, J. Kourlas, Nicholas John Hadley, Y. Fisyak, J. H. Christenson, S. Blessing, Scott Snyder, H. E. Montgomery, R. Markeloff, I. Adam, P. Rubinov, K. W. Merritt, J. F. Bartlett, A. Narayanan, F. Borcherding, C. Shaffer, D. Cullen-Vidal, K. Genser, A. Goldschmidt, N. N. Biswas, Sharon Hagopian, M. Demarteau, John Hobbs, A. K.A. Maciel, Yanwen Liu, Raymond Brock, Boaz Klima, Erich Varnes, L. Lueking, H. da Motta, J. G.R. Lima, S. Chopra, F. Lobkowicz, B. Gobbi, K. Bazizi, E. Oltman, Daniel John Karmgard, C. K. Jung, M. Sosebee, A. S. Ito, P. Padley, T. Rockwell, Iain Alexander Bertram, Michael Rijssenbeek, Young-Sang Yu, A. L. Lyon, D. Norman, E. Amidi, J. V.D. Wirjawan, Shuichi Kunori, N. Grossman, R. Piegaia, Anurag Gupta, N. Amos, S. Willis, Alexey Volkov, J. Yang, Jing Li, M. Pang, J. Bantly, V. N. Evdokimov, D.S. Koltick, Quing Zhu, A. N. Galyaev, V. M. Podstavkov, Jasvinder A. Singh, Elizabeth Gallas, M. Fortner, Y. Pischalnikov, Ulrich Heintz, J. Perkins, M. Abolins, H. Jöstlein, T. Yasuda, P. Mooney, B. Pawlik, W. Smart, K. A. Johns, W. E. Cooper, P. Yamin, M. Diesburg, James H Cochran, L. P. Chen, N. K. Mondal, Daniel R Claes, Marvin Johnson, H. T. Diehl, H. Singh, D. Owen, A. Boehnlein, A. V. Kozelov, Andrew Brandt, P. M. Sood, R. Engelmann, J. Tarazi, Emanuela Barberis, S. Mani, J. Z.Y. Jiang, J. Ellison, Mitchell Wayne, H. Schellman, J. M. Kohli, L. T. Goss, H.E. Miettinen, J. Jaques, J. Kotcher, R. Madden, E. A. Kozlovski, L. Rasmussen, H. Haggerty, S. Lökös, Peter W. Draper, Ron Lipton, J. Womersley, Joan A. Guida, M. M. Baarmand, Sarah Catherine Eno, G. Di Loreto, J. Thompson, D. Denisov, Srinivasan Rajagopalan, O. I. Dahl, Thomas Ferbel, Dan Green, N. Graf, K. Streets, Vipin Bhatnagar, B. Gómez, Vyacheslav Klyukhin, Z. H. Zhu, F. Nang, R. Partridge, Brajesh C Choudhary, H. S. Mao, D. L. Adams, A. Baden, Shashikant Dugad, Bobby Samir Acharya, G. C. Blazey, H. A. Neal, H. C. Shankar, J. T. Linnemann, R. Yamada, M. Goforth, S. H. Ahn, Jinhong Yu, A. Klatchko, F. Landry, John Rutherfoord, D. Edmunds, E. W. Anderson, Mary Beth Adams, Andre Sznajder, M. D. Peters, James C. Green, K. S. Hahn, Allen Mincer, L. Oesch, D. Cutts, Sebastian Grinstein, Michael A. Strauss, Greg Landsberg, T. McKibben, A. V. Kostritskiy, T. L. Geld, Sissel Hansen, C. Boswell, Natalie A. Roe, M. Paterno, Alexander Vorobiev, Suman Bala Beri, R. Jesik, S. Glenn, J. McKinley, D. A. Stoianova, Wagner Carvalho, D. Vititoe, R. J. Genik, S. A. Jerger, A. Leflat, W. G. Cobau, M. I. Martin, J. S. Kang, J. McDonald, S. Banerjee, V. Balamurali, B. G. Pope, Elizaveta Shabalina, J. T. White, S. Peryshkin, G. Wang, Alberto Santoro, Seong Keun Kim, J. M. Hauptman, Cecilia Elena Gerber, Jianming Qian, Tong Hu, T. Joffe-Minor, H. E. Fisk, and J. Solomon

Subjects
Physics, Nuclear and High Energy Physics, Particle physics, Tevatron, Elementary particle, Nuclear physics, Particle decay, Mass spectrum, Transverse mass, High Energy Physics::Experiment, Fermilab, Nuclear Experiment, Lepton, Boson
Abstract

A measurement of the mass of the W boson is presented which is based on a sample of 5982 W → eνv decays observed in pp collisions at √s=1.8 TeV with the D∅ detector during the 1992-1993 run. From a fit to the transverse mass spectrum, combined with measurements of the Z boson mass, the W boson mass is measured to be MW=80.350±0.140(stat)±0.165(syst)±0.160(scale) GeV/c 2 . Detailed discussions of the determination of the absolute energy scale, the measured efficiencies, and all systematic uncertainties are presented.

Published
1998
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169. Integrated endoscopic OCT system and in-vivo images of human internal organs

Author

Ludmila B. Snopova, Valentin M. Gelikonov, A. N. Denisenko, Irina N. Kuznetzova, Natalia D. Gladkova, Natalia M. Shakhova, V. V. Pochinko, Felix I. Feldchtein, Valentin Almasov, Grigory V. Gelikonov, Roman V. Kuranov, Andrei Shakhov, Yuri Chumakov, and Alexander M. Sergeev

Subjects
Larynx, Pathology, medicine.medical_specialty, Urinary bladder, medicine.diagnostic_test, business.industry, Stomach, Endoscopy, medicine.anatomical_structure, Optical coherence tomography, Biopsy, medicine, Esophagus, business, Preclinical imaging
Abstract

First results of endoscopic applications of optical coherence tomography (OCT) for in vivo studies of human mucosa in respiratory, gastrointestinal, urinary and genital tracts are presented. A novel endoscopic OCT (EOCT) system has been created that is based on the integration of a sampling arm of an all-optical-fiber interferometer into standard endoscopic devices using their biopsy channel to transmit low-coherence radiation to investigated tissue. We have studied mucous membranes of esophagus, larynx, stomach, urinary bladder, uterine cervix and endometrium as typical localization for carcinomatous processes. Images of tumor tissues versus healthy tissues have been recorded and analyzed. Violations of well-defined stratified healthy mucosa structure in cancered tissue is distinctly seen by EOCT, thus making this technique promising for early diagnosis of tumors and precise guiding of excisional biopsy.© (1998) COPYRIGHT SPIE--The International Society for Optical Engineering. Downloading of the abstract is permitted for personal use only.

Published
1998
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170. Endoscopic OCT for in-vivo imaging of precancer and cancer states of human mucosa

Author

Valentin Almasov, Natalia M. Shakhova, Natalia D. Gladkova, Irina N. Kuznetzova, A. N. Denisenko, Grigory V. Gelikonov, Roman V. Kuranov, Valentin M. Gelikonov, Ludmila B. Snopova, Alexander M. Sergeev, and Felix I. Feldchtein

Subjects
Pathology, medicine.medical_specialty, medicine.diagnostic_test, business.industry, Stomach, Cancer, medicine.disease, Endoscopy, medicine.anatomical_structure, Optical coherence tomography, Biopsy, medicine, Sampling (medicine), Esophagus, business, Preclinical imaging
Abstract

First results of endoscopic applications of optical coherence tomography for in vivo studies of human mucosa in gastrointestinal and genital tracts are presented. A novel endoscopic OCT system has ben created that is based on the integration of a sampling arm of an all-optical-fiber interferometer into standard endoscopic devices using their biopsy channel to transmit low-coherence radiation to investigated tissue. We have studied mucous membranes of esophagus, stomach and uterine cervix as typical localization for carcinomatous processes. Images of tumor tissues versus healthy tissues have been recorded and analyzed. Violations of well-defined stratified healthy mucosa structure in cancerous tissue is distinctly seen by EOCT, thus making this technique promising for early diagnosis of tumors and precise guiding of excisional biopsy.

Published
1998
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171. Design and performance of an endoscopic OCT system for in vivo studies of human mucosa

Author

Natalia D. Gladkova, Grigory V. Gelikonov, A. M. Sergeev, Natalia M. Shakhova, A. N. Denisenko, I. A. Kuznetzova, Felix I. Feldchtein, O.S. Streltzova, Roman V. Kuranov, and Valentin M. Gelikonov

Subjects
Scanner, Materials science, genetic structures, medicine.diagnostic_test, business.industry, Image quality, Superluminescent diode, Interferometry, Optics, Optical coherence tomography, medicine, Optical tomography, business, Angle-resolved low-coherence interferometry, Coherence (physics)
Abstract

A key problem for endoscopic application of optical coherence tomography (OCT) is to provide a reliable and convenient access of probing low-coherence radiation to the surface of internal organs. Here, the authors describe the design and performance of their OCT systems integrated in standard endoscopes, operating in parallel with them and thus enhancing essentially the capabilities of endoscopy as a whole. Implementation of an extended flexible arm of the OCT interferometer to provide access to the studied tissue is based on the usage of polarization maintaining fibers for transportation of the low coherence light. The sampling arm of the fiber interferometer is terminated by a newly developed miniaturized electro-mechanical unit that controls the lateral scanning process. The probe beam swinging on the tissue surface approaches 2 mm. As a source of radiation the authors employ a superluminescent diode with a central frequency of 830 nm, bandwidth of 30 nm, and power of 1.5 mW. In-depth scanning is performed with an integrated piezo-optical modulator that introduces the difference in the length arms of the interferometer. With a scanning rate of 30 cm/s and an image depth of 3 mm, an OCT picture is acquired in approximately 1 s. This rate is sufficient to eliminate the effect of internal organ movement on the image quality. The electro-mechanical scanner has a size that fits the diameter and the curvature radius of an endoscope biopsy channel.

Published
1998
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173. [Features of uterine contractile function in intrauterine fetal death]

Author

L M, Zaĭtsev, O N, Denisenko, and A P, Makarovskiĭ

Subjects
Uterine Contraction, Pregnancy, Animals, Embryonic Development, Female, Abruptio Placentae, Fetal Death, Rats
Abstract

Experiments on 528 pregnant rats studied the specific features of uterine contractility in pre- (7.2%), postimplantation (5.69%), and intrauterine (1.14%) fetal deaths and in ablatio placentae (0.57%) which spontaneously occurred in this group of animals. By applying the multiparametric approach and the methods of the image recognition theory, the authors showed that despite its onset periods, fetal deaths resulted in reduced uterine contractility. It is concluded that the present study provides experimental evidence for the development of weak clinical uterine activity in fetal death in different periods of pregnancy. At the same time, myometrial responses to oxytocin decrease.

Published
1997

174. Dosimetry and Treatment Planning in High Dose Rate Cf-252 Brachytherapy

Author

A. A. Omarov, V. A. Kozlov, V. O. Sidorchenkov, V. N. Ivanov, O. N. Denisenko, I. M. Chernichenko, and V. N. Chekhonadsky

Subjects
Radiation therapy, Intracavitary radiotherapy, business.industry, medicine.medical_treatment, Brachytherapy, Medicine, Dosimetry, Dose distribution, business, Radiation treatment planning, Dose rate, Nuclear medicine, Quality assurance
Abstract

The report discusses physical and technological problems of quality assurance for radiotherapy in intracavitary application of Cf-252. Main reasons of errors and methods of their correction at every stage of preparations and performance of intracavitary radiotherapy with Cf-252, i.e. in measurement of radiation characteristics for Cf-252 source, in determination of dose distribution from single Cf-252 sources, at insertion of sources to the cavity and their fixation and in calculation of dose distribution for actual topographic and anatomic features of the patients, have been studied.

Published
1997
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175. Intracavitary Neutron Therapy for Malignant Rectal Tumors using High Activity Cf-252 Sources

Author

V. O. Sidorchenkov, V. N. Ivanov, O. N. Denisenko, and V. A. Kozlov

Subjects
medicine.medical_specialty, business.industry, Colorectal cancer, medicine.medical_treatment, Brachytherapy, Perforation (oil well), Rectum, Rectal Tumors, medicine.disease, Rectosigmoid Region, medicine.anatomical_structure, medicine, High activity, Premedication, Medical physics, Radiology, business
Abstract

Radiotherapeutic unit “ANET-V” is the first Russian unit for HDR Cf-252 brachytherapy. We developed in details the technique of intracavitary brachytherapy of different parts of the rectum, based on remote afterloading of high activity sources under direct visual control. Intracavitary brachytherapy in different volumes and with different aim was done to 61 patients with rectal cancer at the age of 36 to 68. Single dose on tumor base was 5–10 Gy and total dose was 10–50 Gy, RBE — 3. The diagnosis of all the patients was verified morphologically. Staging was performed according to the international classification ( The tumor localized in the anal part- 2 patients, in the lower-ampulla part of the rectum in 26 cases; in the medium-ampulla — 13 cases; in the upper-ampulla part — 12 patients and in rectosigmoid region 8 cases). We have not diagnosed any complications during pre-irradiation preparation (that is no trauma of proctal mucosa and tumor, no bleeding and perforation of proctal wall). There were no complications during intracavitary brachytherpy and following full-term of the treatment, i.e. our patients did not reveal bleeding, perforation of rectum wall, acute radiation damage of proctal mucosa and proctal wall. Anal sphincter function was not broken. Premedication is not needed. The main dosimetric and technical characteristics of “ANET-V” unit were investigated in clinic. We have designed a set of technical means for intracavitary brachytherapy in rectal tumors. Equipment has patents, the Gold Medal of the World exhibition “Brussels Evrika-94”.

Published
1997
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176. Isolation of song-regulated genes in the brain of songbirds

Author

C V, Mello, E D, Jarvis, N, Denisenko, and M, Rivas

Subjects
Birds, DNA, Complementary, Behavior, Animal, Animals, Brain, Cloning, Molecular, Genes, Immediate-Early, Polymerase Chain Reaction, In Situ Hybridization, Plasmids
Published
1997

177. [The choice of timing and methods in the surgical treatment of thoracic bone injuries in combined closed thoracic injuries during acute and early periods of traumatic disease]

Author

G G, Roshchin, V V, Burluka, N I, Tutchenko, V N, Denisenko, I P, Shlapak, and N N, Baramiia

Subjects
Adult, Male, Time Factors, Thoracic Injuries, Acute Disease, Humans, Female, Middle Aged, Wounds, Nonpenetrating, Models, Biological
Abstract

Clinico-statistical analysis of the treatment results of 624 injured persons for the period from 1990 till 1995 year was conducted. In 509 (81.6%) of them the combined closed thoracic trauma was revealed, in 15 (18.4%)--the isolated closed affection of the skull, thorax, abdomen and extremities have occurred. The anatomic-functional model of the injury severity and prognosis outcome estimation was elaborated, an optimal timing and surgical treatment methods of the thoracic cage bones injury was substantiated, what have promoted to lower lethality from 50%--in injured persons, operated on without taking into account the trauma severity and prognosis outcome, to 31.6%--in operated on in the postponed order.

Published
1997

178. [Physico-technological standards of remote neutron radiotherapy and quality assurance (literature review)]

Author

A F, Tsyb, O N, Denisenko, Iu S, Mardynskiĭ, Iu Iu, Ostroukhov, and V I, Potetnia

Subjects
Neutrons, Quality Assurance, Health Care, Radiotherapy, Humans
Abstract

Issues in physico-technological support of remote neutron therapy are discussed. On the basis of evaluation of the literature, conclusion is made that a number of important problems are still to be solved.

Published
1997

179. The Azimuthal Decorrelation of Jets Widely Separated in Rapidity

Author

S. Abachi, B. Abbott, M. Abolins, B. S. Acharya, I. Adam, D. L. Adams, M. Adams, S. Ahn, H. Aihara, J. Alitti, G. Álvarez, G. A. Alves, E. Amidi, N. Amos, E. W. Anderson, S. H. Aronson, R. Astur, R. E. Avery, M. M. Baarmand, A. Baden, V. Balamurali, J. Balderston, B. Baldin, S. Banerjee, J. Bantly, J. F. Bartlett, K. Bazizi, J. Bendich, S. B. Beri, I. Bertram, V. A. Bezzubov, P. C. Bhat, V. Bhatnagar, M. Bhattacharjee, A. Bischoff, N. Biswas, G. Blazey, S. Blessing, P. Bloom, A. Boehnlein, N. I. Bojko, F. Borcherding, J. Borders, C. Boswell, A. Brandt, R. Brock, A. Bross, D. Buchholz, V. S. Burtovoi, J. M. Butler, W. Carvalho, D. Casey, H. Castilla-Valdez, D. Chakraborty, S.-M. Chang, S. V. Chekulaev, L.-P. Chen, W. Chen, S. Choi, S. Chopra, B. C. Choudhary, J. H. Christenson, M. Chung, D. Claes, A. R. Clark, W. G. Cobau, J. Cochran, W. E. Cooper, C. Cretsinger, D. Cullen-Vidal, M. A. C. Cummings, D. Cutts, O. I. Dahl, K. De, M. Demarteau, N. Denisenko, D. Denisov, S. P. Denisov, H. T. Diehl, M. Diesburg, G. Di Loreto, R. Dixon, P. Draper, J. Drinkard, Y. Ducros, S. R. Dugad, D. Edmunds, J. Ellison, V. D. Elvira, R. Engelmann, S. Eno, G. Eppley, P. Ermolov, O. V. Eroshin, V. N. Evdokimov, S. Fahey, T. Fahland, M. Fatyga, M. K. Fatyga, J. Featherly, S. Feher, D. Fein, T. Ferbel, G. Finocchiaro, H. E. Fisk, Y. Fisyak, E. Flattum, G. E. Forden, M. Fortner, K. C. Frame, P. Franzini, S. Fuess, E. Gallas, A. N. Galyaev, T. L. Geld, R. J. Genik II, K. Genser, C. E. Gerber, B. Gibbard, V. Glebov, S. Glenn, J. F. Glicenstein, B. Gobbi, M. Goforth, A. Goldschmidt, B. Gómez, G. Gomez, P. I. Goncharov, J. L. González Solís, H. Gordon, L. T. Goss, N. Graf, P. D. Grannis, D. R. Green, J. Green, H. Greenlee, G. Griffin, N. Grossman, P. Grudberg, S. Grünendahl, W. X. Gu, G. Guglielmo, J. A. Guida, J. M. Guida, W. Guryn, S. N. Gurzhiev, P. Gutierrez, Y. E. Gutnikov, N. J. Hadley, H. Haggerty, S. Hagopian, V. Hagopian, K. S. Hahn, R. E. Hall, S. Hansen, R. Hatcher, J. M. Hauptman, D. Hedin, A. P. Heinson, U. Heintz, R. Hernández-Montoya, T. Heuring, R. Hirosky, J. D. Hobbs, B. Hoeneisen, J. S. Hoftun, F. Hsieh, Tao Hu, Ting Hu, Tong Hu, T. Huehn, S. Igarashi, A. S. Ito, E. James, J. Jaques, S. A. Jerger, J. Z.-Y. Jiang, T. Joffe-Minor, H. Johari, K. Johns, M. Johnson, H. Johnstad, A. Jonckheere, M. Jones, H. Jöstlein, S. Y. Jun, C. K. Jung, S. Kahn, G. Kalbfleisch, J. S. Kang, R. Kehoe, M. L. Kelly, L. Kerth, C. L. Kim, S. K. Kim, A. Klatchko, B. Klima, B. I. Klochkov, C. Klopfenstein, V. I. Klyukhin, V. I. Kochetkov, J. M. Kohli, D. Koltick, A. V. Kostritskiy, J. Kotcher, J. Kourlas, A. V. Kozelov, E. A. Kozlovski, M. R. Krishnaswamy, S. Krzywdzinski, S. Kunori, S. Lami, G. Landsberg, J-F. Lebrat, A. Leflat, H. Li, J. Li, Y. K. Li, Q. Z. Li-Demarteau, J. G. R. Lima, D. Lincoln, S. L. Linn, J. Linnemann, R. Lipton, Y. C. Liu, F. Lobkowicz, S. C. Loken, S. Lökös, L. Lueking, A. L. Lyon, A. K. A. Maciel, R. J. Madaras, R. Madden, S. Mani, H. S. Mao, S. Margulies, R. Markeloff, L. Markosky, T. Marshall, M. I. Martin, B. May, A. A. Mayorov, R. McCarthy, T. McKibben, J. McKinley, T. McMahon, H. L. Melanson, J. R. T. de Mello Neto, K. W. Merritt, H. Miettinen, A. Mincer, J. M. de Miranda, C. S. Mishra, N. Mokhov, N. K. Mondal, H. E. Montgomery, P. Mooney, H. da Motta, M. Mudan, C. Murphy, F. Nang, M. Narain, V. S. Narasimham, A. Narayanan, H. A. Neal, J. P. Negret, E. Neis, P. Nemethy, D. Nešić, M. Nicola, D. Norman, L. Oesch, V. Oguri, E. Oltman, N. Oshima, D. Owen, P. Padley, M. Pang, A. Para, C. H. Park, Y. M. Park, R. Partridge, N. Parua, M. Paterno, J. Perkins, A. Peryshkin, M. Peters, H. Piekarz, Y. Pischalnikov, V. M. Podstavkov, B. G. Pope, H. B. Prosper, S. Protopopescu, D. Pušeljić, J. Qian, P. Z. Quintas, R. Raja, S. Rajagopalan, O. Ramirez, M. V. S. Rao, P. A. Rapidis, L. Rasmussen, A. L. Read, S. Reucroft, M. Rijssenbeek, T. Rockwell, N. A. Roe, P. Rubinov, R. Ruchti, J. Rutherfoord, A. Santoro, L. Sawyer, R. D. Schamberger, H. Schellman, J. Sculli, E. Shabalina, C. Shaffer, H. C. Shankar, R. K. Shivpuri, M. Shupe, J. B. Singh, V. Sirotenko, W. Smart, A. Smith, R. P. Smith, R. Snihur, G. R. Snow, J. Snow, S. Snyder, J. Solomon, P. M. Sood, M. Sosebee, M. Souza, A. L. Spadafora, R. W. Stephens, M. L. Stevenson, D. Stewart, D. A. Stoianova, D. Stoker, K. Streets, M. Strovink, A. Sznajder, P. Tamburello, J. Tarazi, M. Tartaglia, T. L. Taylor, J. Thompson, T. G. Trippe, P. M. Tuts, N. Varelas, E. W. Varnes, P. R. G. Virador, D. Vititoe, A. A. Volkov, A. P. Vorobiev, H. D. Wahl, G. Wang, J. Warchol, G. Watts, M. Wayne, H. Weerts, F. Wen, A. White, J. T. White, J. A. Wightman, J. Wilcox, S. Willis, S. J. Wimpenny, J. V. D. Wirjawan, J. Womersley, E. Won, D. R. Wood, H. Xu, R. Yamada, P. Yamin, C. Yanagisawa, J. Yang, T. Yasuda, P. Yepes, C. Yoshikawa, S. Youssef, J. Yu, Y. Yu, Q. Zhu, Z. H. Zhu, D. Zieminska, A. Zieminski, E. G. Zverev, and A. Zylberstejn

Subjects
Physics, Particle physics, Astrophysics::High Energy Astrophysical Phenomena, High Energy Physics::Phenomenology, Tevatron, General Physics and Astronomy, FOS: Physical sciences, Parton, High Energy Physics - Experiment, Nuclear physics, High Energy Physics - Experiment (hep-ex), Pseudorapidity, Rapidity, High Energy Physics::Experiment, Fermilab, Resummation, Parton shower, Nuclear Experiment, Decorrelation
Abstract

This study reports the first measurement of the azimuthal decorrelation between jets with pseudorapidity separation up to five units. The data were accumulated using the D{\O}detector during the 1992--1993 collider run of the Fermilab Tevatron at $\sqrt{s}=$ 1.8 TeV. These results are compared to next--to--leading order (NLO) QCD predictions and to two leading--log approximations (LLA) where the leading--log terms are resummed to all orders in $\alpha_{\scriptscriptstyle S}$. The final state jets as predicted by NLO QCD show less azimuthal decorrelation than the data. The parton showering LLA Monte Carlo {\small HERWIG} describes the data well; an analytical LLA prediction based on BFKL resummation shows more decorrelation than the data., Comment: 6 pages with 4 figures, all uuencoded and gzipped

Published
1996
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180. TOP-QUARK SEARCH WITH THE D0 1992-1993 DATA SAMPLE

Author

R. Astur, T. Heuring, B. G. Pope, H. L. Melanson, P. Z. Quintas, T. Huehn, D. Buchholz, D. Fein, Erich Varnes, P. Tamburello, J. H. Christenson, J. M. De Miranda, Heng Xu, J. Alitti, J. Bantly, C. Cretsinger, M. Strovink, M. Mohammadi-Baarmand, D. Nešić, Haifeng Li, E. Shabalina, J. T. White, Meenakshi Narain, A. Peryshkin, E. James, J. Bendich, A. Narayanan, Allan G Clark, Gregory R Snow, Andrew Brandt, R. Engelmann, Liu Chen, N. Grossman, H.E. Miettinen, B. May, R. Snihur, P. Grudberg, T. McKibben, M. V. S. Rao, R. J. Madaras, Gilvan Alves, S. Youssef, Y. E. Gutnikov, Alexander Vorobiev, R. E. Lanou, Alberto Santoro, J. Kourlas, M.K. Fatyga, Robert Kehoe, M. Bhattacharjee, G. Álvarez, G. Eppley, B. Gobbi, R. Hirosky, N. Varelas, J. Li, M. H.G. Souza, J. Balderston, J. Kotcher, J. G.R. Lima, John Hobbs, Y. H. Zhou, H. E. Montgomery, S. A. Jerger, A. Leflat, D. Lincoln, Eunil Won, P. Bloom, Young-Sang Yu, N. Graf, Jasvinder A. Singh, D. Hedin, J. A. Wightman, A. S. Ito, W. G. Cobau, M. I. Martin, G. E. Forden, A. P. Heinson, J. S. Kang, T. L. Taylor, K. Streets, S. Fahey, Vipin Bhatnagar, N. I. Bojko, S. M. Chang, R. Partridge, E. Flattum, H. Johnstad, T. Yasuda, Ph. Mangeot, I. Bertram, J. Jaques, Bruno Mansoulie, P. A. Rapidis, G. Griffin, E. Gallas, J. Featherly, D. P. Stoker, J. A. Guida, D. Casey, R. E. Hall, V. Glebov, Marvin Johnson, A. L. Read, Heriberto Castilla-Valdez, T. Joffe-Minor, C. Yanagisawa, S. Gao, K. Denisenko, M. L. Stevenson, C. H. Park, F. Lobkowicz, S. Fuess, A. V. Kozelov, A. Kernan, H. S. Mao, D. L. Adams, J. S. Hoftun, J. N. Butler, P. D. Grannis, L. Z. Wang, A. L. Lyon, H. Piekarz, A. Jonckheere, H. Johari, V. Balamurali, T. Rockwell, D. Pušeljić, S. Margulies, S. Lami, Ron Lipton, Raymond Brock, Boaz Klima, H. E. Fisk, R. L. Dixon, Shuichi Kunori, Stephan Linn, Michael Rijssenbeek, J. Solomon, A. Pluquet, P.F. Ermolov, Yanxi Zhang, D. Edmunds, S. Krzywdzinski, B. Baldin, W. Y. Chen, Y. Ducros, E. Neis, V. S. Burtovoi, C. T. Murphy, V. I. Kochetkov, N. Oshima, Daria Zieminska, Rajendran Raja, D. Norman, V. N. Evdokimov, J. Warchol, J. Womersley, S. Willis, D.S. Koltick, A. Zylberstejn, R. L. McCarthy, S. Rusin, C. Klopfenstein, R. D. Schamberger, H. Greenlee, A. N. Galjaev, J. T. Linnemann, J. M. Guida, A. Smith, J. F. Lebrat, P. Draper, M. Pang, Paolo Franzini, B. I. Klochkov, G. Finocchiaro, M. D. Peters, S. C. Loken, Brad Abbott, B. Gibbard, V. A. Bezzubov, J. P. Negret, R. P. Smith, I. V. Mandrichenko, Dhiman Chakraborty, M. J. Glaubman, A. Bross, J. M. Hauptman, V. S. Narasimham, Thomas G Trippe, W. X. Gu, Nikolai Mokhov, L. Markosky, L. Oesch, S. Durston-Johnson, Michael Shupe, V. D. Elvira, P. I. Goncharov, Welathantri Gd Dharmaratna, Peter Nemethy, A. White, N. Denisenko, Serban Protopopescu, S. Reucroft, W. Guryn, V. Sirotenko, W. E. Cooper, Daniel R Claes, R. Hernández-Montoya, A. Milder, C. Yoshikawa, A. A. Mayorov, Jianming Qian, O. V. Eroshin, J. Sculli, M. L. Kelly, P. Yamin, S. Feher, C. Boswell, Howard Gordon, K. C. Frame, O. Ramirez, Tong Hu, M. K. Fatyga, S. Abachi, J. Wang, Harrison Prosper, C. Murphy, G. Di Loreto, Ting Hu, Sharon Hagopian, C. Shaffer, D. Cullen-Vidal, K. Genser, Suman Bala Beri, N. N. Biswas, A. K.A. Maciel, S. Mani, S. P. Denisov, A. Zieminski, R. Madden, Brajesh C Choudhary, S. Glenn, J. McKinley, D. A. Stoianova, M. Sosebee, M. R. Krishnaswamy, L. Rasmussen, Pushpalatha C Bhat, M. Mudan, F. Hsieh, D. Vititoe, Y. S. Zhu, S. Y. Jun, R. J. Genik, J. Yu, S. Grünendahl, A. Para, N. Parua, A. Goldschmidt, D. Denisov, Matthew Jones, B. Hoeneisen, Sergey Chekulaev, J. Teiger, Bobby Samir Acharya, H. A. Neal, H. C. Shankar, Srinivasan Rajagopalan, T. Fahland, C. L. Kim, Hiroaki Aihara, Thomas Ferbel, Dan Green, J. Wilcox, A. Taketani, I. Adam, P. Rubinov, Y. M. Park, P. M. Tuts, S.A. Kahn, M. Abolins, K. W. Merritt, A. L. Spadafora, J. F. Bartlett, M. Demarteau, R. E. Avery, Yanwen Liu, M. Goforth, L. Lueking, P. Mooney, A. Klatchko, R. K. Shivpuri, Yu Fisyak, Y. Pischalnikov, Ulrich Heintz, J. Perkins, H. Jöstlein, D. Stewart, N. K. Mondal, S. Igarashi, P. R. G. Virador, S. N. Gurzhiev, M. Diesburg, D. Owen, Q. Z. Li-Demarteau, H. T. Diehl, A. Boehnlein, J. Drinkard, M. Tartaglia, N. A. Roe, J. Tarazi, S. Chopra, M. Chung, Randy Ruchti, P. M. Sood, J. Ellison, C. S. Mishra, R. Hatcher, Kaushik De, R. W. Stephens, Quing Zhu, Vasken Hagopian, S. H. Aronson, H. Weerts, C. K. Jung, Laurent Chevalier, C. E. Gerber, Stephen Wimpenny, M. A. C. Cummings, T. Marshall, Darien Wood, Nicholas John Hadley, S. Blessing, Scott Snyder, R. Markeloff, J. Borders, J. Z.Y. Jiang, L. T. Goss, E. A. Kozlovski, H. Haggerty, S. Lökös, W. A. Wenzel, L. T. Kerth, N. Amos, J. Yang, V. M. Podstavkov, M. Fortner, A. Bischoff, A. V. Kostritskiy, Sissel Hansen, F. Nang, K. Bazizi, M. D. Marx, H. D. Wahl, Sun Kee Kim, E. W. Anderson, Allen Mincer, Christina Gao, P. Padley, Alexey Volkov, James H Cochran, Mitchell Wayne, H. Schellman, J. M. Kohli, J. Thompson, B. Gómez, L. Sawyer, Z. H. Zhu, Shashikant Dugad, V. Oguri, R. Demina, W. Smart, K. A. Johns, E. Amidi, J. V.D. Wirjawan, J. R. T. de Mello Neto, K. S. Hahn, D. Cutts, Greg Landsberg, T. L. Geld, M. Paterno, A. Baden, G. C. Blazey, R. Yamada, S. H. Ahn, Orin I. Dahl, John Rutherfoord, Mary Beth Adams, James C. Green, F. Borcherding, E. Oltman, Sarah Catherine Eno, Vyacheslav Klyukhin, and Ying Li

Subjects
Physics, Quark, Top quark, Particle physics, Muon, Computer Science::Information Retrieval, Astrophysics::High Energy Astrophysical Phenomena, High Energy Physics::Phenomenology, Particle identification, Luminosity, Standard Model, Nuclear physics, Particle decay, Production (computer science), High Energy Physics::Experiment
Abstract

We present results on the search for the top quark in {ital p{bar p}} collisions at {radical}{ital s} =1.8 TeV with an integrated luminosity of 13.5{plus_minus}1.6 pb{sup {minus}1}. We have considered {ital t{bar t}} production in the standard model using electron and muon dilepton decay channels ({ital t{bar t}}{r_arrow}{ital e}{mu}+jets, {ital ee}+jets, and {mu}{mu}+jets) and single-lepton decay channels ({ital t{bar t}}{r_arrow}{ital e}+jets and {mu}+jets) with and without tagging of {ital b} quark jets. An analysis of these data optimized for top quark masses below 140 GeV/{ital c}{sup 2} gives a lower top quark mass limit of 128 GeV/{ital c}{sup 2}. An analysis optimized for higher top quark masses yields 9 events with an expected background of 3.8{plus_minus}0.9. If we assume that the excess is due to {ital t{bar t}} production, and assuming a top quark mass of 180 GeV/{ital c}{sup 2}, we obtain a cross section of 8.2{plus_minus}5.1 pb.

Published
1995

182. [Study of plant lectins from Viscum album using monoclonal antibodies]

Author

A G, Tonevitskiĭ, V A, Rakhmanova, A T, Shamshiev, E A, Usachaeva, I I, Agapov, S A, Prokov'ev, O N, Denisenko, U, Pfuller, and R, Eifler

Subjects
Protein Synthesis Inhibitors, Hybridomas, Plants, Medicinal, Cell-Free System, Blotting, Western, Antibodies, Monoclonal, Asialoglycoproteins, Ricin, Cross Reactions, Mistletoe, Solutions, Mice, Lectins, Animals, Rabbits, alpha-Fetoproteins, Plant Lectins, Fetuins, Protein Binding, Toxins, Biological
Abstract

Monoclonal antibodies (monAT) against both native (TA5, TB12) and denatured (TB33, TB35) plant toxin ML1 from Viscum album have been obtained. The interaction of monAT against native toxin with its isoforms ML2 and ML3 was investigated. It was shown that monAT TA5 to A-chain of ML1 toxin cross-reacted with ML2 and ML3 isoforms. TA5 did not inhibit enzyme activity of A-chain in cell-free rabbit reticulocyte system. It was shown that monAT TB12 reacted with galactose-binding site of B-subunit. Both monAT had no cross-reactions with plant toxin ricin. The binding constants for TA5 with ML1, ML2, ML3 respectively were 4.3.10(7) M-1, 1.2.10(7) M-1, and 0.3.10(7) M-1. The binding constants for TB12 were 2.10(7) M-1 with ML1 toxin, and more than 10(6) M-1 with ML2 and ML3. The nature of heterogeneity in ML toxin family is discussed. Test-systems for ML1 determination in different V. album extracts are suggested.

Published
1995

183. Alterations in protein synthesis induced by C2 toxin in 3T3 cells

Author

Tatyana Sklyarova, Victor S. Prisyazhnoy, Oleg N. Denisenko, Vladimir Kostyukovski, and Vadim V. Sharov

Subjects
Botulinum Toxins, Protein synthesis regulation, Biophysics, Clostridium botulinum type C, Tropomyosin, Biology, medicine.disease_cause, Biochemistry, Filamentous actin, Mice, Structural Biology, Genetics, medicine, Protein biosynthesis, Clostridium botulinum, Animals, Electrophoresis, Gel, Two-Dimensional, Molecular Biology, Actin, Cell Size, Mice, Inbred BALB C, Toxin, Proteins, Cell Biology, 3T3 Cells, Molecular biology, Actin filament depolymerization, Actins, Cell biology, C2 toxin, ADP-ribosylation, Polyribosomes, Protein Biosynthesis
Abstract

We have studied the effect of actin skeleton depolymerisation induced by C2 toxin on protein synthesis in 3T3 cells. The toxin that was purified from culture medium of Clostridium botulinum type C was shown to specifically ADP-ribosylate actin in vitro and in vivo. Cells exposed to C2 toxin were rounded off, which was accompanied by disappearance of stress fibers. The rate of total protein synthesis decreased two-three times in the treated cells. This correlated with the reduction in amount of polyribosomes. The rates of specific protein synthesis were compared using 2D electrophoresis of pulse-labeled proteins. Dramatic changes were observed in the synthesis of a small group of cellular proteins. Our results indicate that actin filament depolymerization affects gene expression at the level of translation and/or through the control of mRNA concentrations.

Published
1995

184. OBSERVATION OF THE TOP-QUARK

Author

S. Abachi, B. Abbott, M. Abolins, B. S. Acharya, I. Adam, D. L. Adams, M. Adams, S. Ahn, H. Aihara, J. Alitti, G. Álvarez, G. A. Alves, E. Amidi, N. Amos, E. W. Anderson, S. H. Aronson, R. Astur, R. E. Avery, A. Baden, V. Balamurali, J. Balderston, B. Baldin, J. Bantly, J. F. Bartlett, K. Bazizi, J. Bendich, S. B. Beri, I. Bertram, V. A. Bezzubov, P. C. Bhat, V. Bhatnagar, M. Bhattacharjee, A. Bischoff, N. Biswas, G. Blazey, S. Blessing, A. Boehnlein, N. I. Bojko, F. Borcherding, J. Borders, C. Boswell, A. Brandt, R. Brock, A. Bross, D. Buchholz, V. S. Burtovoi, J. M. Butler, D. Casey, H. Castilla-Valdez, D. Chakraborty, S.-M. Chang, S. V. Chekulaev, L.-P. Chen, W. Chen, L. Chevalier, S. Chopra, B. C. Choudhary, J. H. Christenson, M. Chung, D. Claes, A. R. Clark, W. G. Cobau, J. Cochran, W. E. Cooper, C. Cretsinger, D. Cullen-Vidal, M. Cummings, D. Cutts, O. I. Dahl, K. De, M. Demarteau, R. Demina, K. Denisenko, N. Denisenko, D. Denisov, S. P. Denisov, W. Dharmaratna, H. T. Diehl, M. Diesburg, G. Di Loreto, R. Dixon, P. Draper, J. Drinkard, Y. Ducros, S. R. Dugad, S. Durston-Johnson, D. Edmunds, A. O. Efimov, J. Ellison, V. D. Elvira, R. Engelmann, S. Eno, G. Eppley, P. Ermolov, O. V. Eroshin, V. N. Evdokimov, S. Fahey, T. Fahland, M. Fatyga, M. K. Fatyga, J. Featherly, S. Feher, D. Fein, T. Ferbel, G. Finocchiaro, H. E. Fisk, Yu. Fisyak, E. Flattum, G. E. Forden, M. Fortner, K. C. Frame, P. Franzini, S. Fredriksen, S. Fuess, A. N. Galjaev, E. Gallas, C. S. Gao, S. Gao, T. L. Geld, R. J. Genik II, K. Genser, C. E. Gerber, B. Gibbard, M. Glaubman, V. Glebov, S. Glenn, J. F. Glicenstein, B. Gobbi, M. Goforth, A. Goldschmidt, B. Gomez, P. I. Goncharov, H. Gordon, L. T. Goss, N. Graf, P. D. Grannis, D. R. Green, J. Green, H. Greenlee, G. Griffin, N. Grossman, P. Grudberg, S. Grünendahl, J. A. Guida, J. M. Guida, W. Guryn, S. N. Gurzhiev, Y. E. Gutnikov, N. J. Hadley, H. Haggerty, S. Hagopian, V. Hagopian, K. S. Hahn, R. E. Hall, S. Hansen, R. Hatcher, J. M. Hauptman, D. Hedin, A. P. Heinson, U. Heintz, R. Hernandez-Montoya, T. Heuring, R. Hirosky, J. D. Hobbs, B. Hoeneisen, J. S. Hoftun, F. Hsieh, Ting Hu, Tong Hu, T. Huehn, S. Igarashi, A. S. Ito, E. James, J. Jaques, S. A. Jerger, J. Z.-Y. Jiang, T. Joffe-Minor, H. Johari, K. Johns, M. Johnson, H. Johnstad, A. Jonckheere, H. Jöstlein, S. Y. Jun, C. K. Jung, S. Kahn, J. S. Kang, R. Kehoe, M. Kelly, A. Kernan, L. Kerth, C. L. Kim, S. K. Kim, A. Klatchko, B. Klima, B. I. Klochkov, C. Klopfenstein, V. I. Klyukhin, V. I. Kochetkov, J. M. Kohli, D. Koltick, A. V. Kostritskiy, J. Kotcher, J. Kourlas, A. V. Kozelov, E. A. Kozlovski, M. R. Krishnaswamy, S. Krzywdzinski, S. Kunori, S. Lami, G. Landsberg, R. E. Lanou, J-F. Lebrat, J. Lee-Franzini, A. Leflat, H. Li, J. Li, Y. K. Li, Q. Z. Li-Demarteau, J. G. R. Lima, D. Lincoln, S. L. Linn, J. Linnemann, R. Lipton, Y. C. Liu, F. Lobkowicz, S. C. Loken, S. Lökös, L. Lueking, A. L. Lyon, A. K. A. Maciel, R. J. Madaras, R. Madden, I. V. Mandrichenko, Ph. Mangeot, S. Mani, B. Mansoulié, H. S. Mao, S. Margulies, R. Markeloff, L. Markosky, T. Marshall, M. I. Martin, M. Marx, B. May, A. A. Mayorov, R. McCarthy, T. McKibben, J. McKinley, H. L. Melanson, J. R. T. de Mello Neto, K. W. Merritt, H. Miettinen, A. Milder, C. Milner, A. Mincer, J. M. de Miranda, C. S. Mishra, M. Mohammadi-Baarmand, N. Mokhov, N. K. Mondal, H. E. Montgomery, P. Mooney, M. Mudan, C. Murphy, C. T. Murphy, F. Nang, M. Narain, V. S. Narasimham, A. Narayanan, H. A. Neal, J. P. Negret, E. Neis, P. Nemethy, D. Nešić, D. Norman, L. Oesch, V. Oguri, E. Oltman, N. Oshima, D. Owen, P. Padley, M. Pang, A. Para, C. H. Park, Y. M. Park, R. Partridge, N. Parua, M. Paterno, J. Perkins, A. Peryshkin, M. Peters, H. Piekarz, Y. Pischalnikov, A. Pluquet, V. M. Podstavkov, B. G. Pope, H. B. Prosper, S. Protopopescu, D. Pušeljić, J. Qian, P. Z. Quintas, R. Raja, S. Rajagopalan, O. Ramirez, M. V. S. Rao, P. A. Rapidis, L. Rasmussen, A. L. Read, S. Reucroft, M. Rijssenbeek, T. Rockwell, N. A. Roe, J. M. R. Roldan, P. Rubinov, R. Ruchti, S. Rusin, J. Rutherfoord, A. Santoro, L. Sawyer, R. D. Schamberger, H. Schellman, D. Schmid, J. Sculli, E. Shabalina, C. Shaffer, H. C. Shankar, R. K. Shivpuri, M. Shupe, J. B. Singh, V. Sirotenko, W. Smart, A. Smith, R. P. Smith, R. Snihur, G. R. Snow, S. Snyder, J. Solomon, P. M. Sood, M. Sosebee, M. Souza, A. L. Spadafora, R. W. Stephens, M. L. Stevenson, D. Stewart, F. Stocker, D. A. Stoianova, D. Stoker, K. Streets, M. Strovink, A. Taketani, P. Tamburello, J. Tarazi, M. Tartaglia, T. L. Taylor, J. Teiger, J. Thompson, T. G. Trippe, P. M. Tuts, N. Varelas, E. W. Varnes, P. R. G. Virador, D. Vititoe, A. A. Volkov, E. von Goeler, A. P. Vorobiev, H. D. Wahl, J. Wang, L. Z. Wang, J. Warchol, M. Wayne, H. Weerts, W. A. Wenzel, A. White, J. T. White, J. A. Wightman, J. Wilcox, S. Willis, S. J. Wimpenny, J. V. D. Wirjawan, Z. Wolf, J. Womersley, E. Won, D. R. Wood, H. Xu, R. Yamada, P. Yamin, C. Yanagisawa, J. Yang, T. Yasuda, C. Yoshikawa, S. Youssef, J. Yu, Y. Yu, Y. Zhang, Y. H. Zhou, Q. Zhu, Y. S. Zhu, Z. H. Zhu, D. Zieminska, A. Zieminski, A. Zinchenko, and A. Zylberstejn

Subjects
Quark, Physics, Top quark, Particle physics, High Energy Physics::Phenomenology, Tevatron, General Physics and Astronomy, FOS: Physical sciences, Bottom quark, Particle identification, High Energy Physics - Experiment, Standard Model, Nuclear physics, High Energy Physics - Phenomenology, Particle decay, High Energy Physics - Experiment (hep-ex), High Energy Physics - Phenomenology (hep-ph), Production (computer science), High Energy Physics::Experiment, Nuclear Experiment
Abstract

The DO collaboration reports on a search for the Standard Model top quark in pbar-p collisions at Sqrt(s)=1.8TeV at the Fermilab Tevatron, with an integrated luminosity of approximately 50pb-1. We have searched for t-tbar production in the dilepton and single-lepton decay channels, with and without tagging of b-quark jets. We observed 17 events with an expected background of 3.8+/-0.6 events. The probability for an upward fluctuation of the background to produce the observed signal is 2.0E-6 (equivalent to 4.6 standard deviations). The kinematic properties of the excess events are consistent with top quark decay. We conclude that we have observed the top quark and measure its mass to be 199^+19_21 (stat.)+/- 22 (syst.)GeV/c**2 and its production cross section to be 6.4 +/- 2.2 pb., Comment: postscript available at http://fnnews.fnal.gov/top_paper_dzero.ps, for further info see http://fnnews.fnal.gov/top_discovery.html

Published
1995

185. The state of actin assembly regulates actin and vinculin expression by a feedback loop

Author

Avri Ben-Ze'ev, Ursula Glück, T. V. Sklyarova, O. N. Denisenko, I. Spector, and Alexander D. Bershadsky

Subjects
Botulinum Toxins, Phalloidine, Polymers, Arp2/3 complex, macromolecular substances, Feedback, Actin remodeling of neurons, Mice, Animals, Humans, Actin-binding protein, Cell Size, biology, Actin remodeling, Cell Biology, 3T3 Cells, Vinculin, Bridged Bicyclo Compounds, Heterocyclic, Actins, Cell biology, Actin Cytoskeleton, Thiazoles, Profilin, biology.protein, RNA, Thiazolidines, MDia1, Lamellipodium, Protein Processing, Post-Translational, HeLa Cells
Abstract

Actin filaments are major determinants of cell shape, motility and adhesion, which control important biological processes including embryonic development and wound healing. These processes are associated with changes in actin assembly, which is regulated by controlling the balance between polymerized and non-polymerized actin. To maintain a significant pool of non-polymerized actin, mechanism(s) linking actin synthesis to its state of polymerization were proposed. We have studied this relationship between actin synthesis and organization by modulating actin assembly using different drugs. Unassembled actin was increased in 3T3 cells using either the Clostridium botulinum C2 toxin, which ADP-ribosylates actin, or by latrunculin A, a Red Sea sponge product, which binds monomeric actin. The synthesis of actin was dramatically reduced in these cells owing to a concomitant decrease in actin RNA level. Similar results were obtained with HeLa cells grown in both monolayer and in suspension, suggesting that cell shape changes associated with drug treatment are not the primary cause for the effect on actin synthesis. In contrast, the scrape-loading of 3T3 cells with phalloidin, a stabilizer of polymerized actin that increased the level of assembled actin, resulted in elevated actin synthesis and RNA content. The expression of vinculin, a major component of adhesion plaques and cell-cell junctions, which is involved in actin-membrane associations, was altered in parallel with that of actin in cells treated with these drugs. The decrease in actin RNA resulted from destabilization of actin mRNA in cells where unassembled actin level was elevated. This is suggested by the unchanged transcription of actin in isolated nuclei from drug-treated cells, and by demonstrating that actin mRNA was degraded faster in cells after C2 toxin treatment than in control cells. This feedback control mechanism is mainly confined to the cytoplasm, as it remained active in enucleated cells. The results suggest the existence of an autoregulatory pathway for the expression of actin and other microfilament-associated proteins which is linked to the state of actin polymerization in the cell.

Published
1995

186. Vicinal n,n interactions in N-chloro substituted diaziridines and oxaziridines : photoelectron spectra and electronic structures

Author

Remir G. Kostyanovsky, Klaus Kowski, Sergej N. Denisenko, Gennady v. Shustov, and Paul Rademacher

Subjects
Bicyclic molecule, Chemistry, Stereochemistry, Organic Chemistry, Chlorine atom, Chemie, Hydrogen atom, Spectral line, Analytical Chemistry, Inorganic Chemistry, Crystallography, Atomic orbital, Ionization, Spectroscopy, Vicinal
Abstract

The He(I) photoelectron spectra of five bicyclic N -chlorodiaziridines ( 6–10 ) and three N -chlorooxaziridines ( 14–16 ), as well as of the corresponding N-H compounds ( 1–5 and 11,13 ), have been recorded and analysed using AM1 calculations. The N -chlorodiaziridines show exo-endo isomerism; however, only one endo isomer ( 10a ) is sufficiently stable for the measurement. The N -chlorooxaziridines are more stable than their N-H precursors. The compounds are characterized by three non-bonding orbitals n + NN , n − NN and n Cl ( N -chlorodiaziridines); n − NO , n Cl and n O ( N -chlorooxaziridines). These orbitals give rise to the first three ionization bands of the compounds. The energy separation of the two n NN MOs of the exo isomers 6b–10b ( Δϵ ≈ 0.3 eV) is smaller than in the corresponding N-H compounds 1–5 ( Δϵ ≈ 0.6 eV), while in the endo isomer 10a ( Δϵ ≈ 1.2 eV) it is larger than in 5 . In the oxaziridines, replacement of the hydrogen atom by a chlorine atom leads to a small stabilization of the n O orbital. These findings can be interpreted by vicinal n X σ∗ N-Hal interactions (X = N or O).

Published
1995

187. The DØ detector

Author

V. N. Evdokimov, Ron Lipton, K. K. Ng, J. Womersley, F. Stocker, D. Cullen-Vidal, K. Genser, H. Weerts, J. Cochran, Daniel J. Smith, P. Xie, S. Feher, V. Manzella, B. Gobbi, K. Denisenko, T. G. Trippe, E. Barasch, Brajesh C Choudhary, H.J. Stredde, Shuichi Kunori, Jasvinder A. Singh, S. Igarashi, Stephen Wimpenny, M. A. C. Cummings, Q. Z. Li-Demarteau, P. J. Kroon, J. N. Butler, P. D. Grannis, J. R. Hubbard, S. Zhang, T. Marshall, Yu.M. Antipov, E. James, N. A. Roe, G. Theodosiou, C. T. Murphy, B. Pi, Matthew Jones, J. A. Guida, G. Krafczyk, C. K. Jung, A. Kirunin, Darien Wood, A. Bross, R. Astur, Nicholas John Hadley, M. L. Good, W. Anderson, H. J. Martin, G. Fanourakis, Ulrich Heintz, K. Streets, B. Baldin, P.R. Vishwanath, D. Xiao, S. Blessing, J. Bantly, Hiroaki Aihara, D. Finley, Y. Ducros, H. Jöstlein, Scott Snyder, Rajendran Raja, M.R. Marcin, M. D. Marx, D. Zieminska, Elizabeth Gallas, S. Fuess, N. Grossman, J. Borders, S. Durston-Johnson, D. Owen, V. Sirotenko, G. Finocchiaro, S. C. Loken, O. V. Eroshin, Daniel R Claes, X. C. Meng, H. D. Wahl, W. Selove, D. Pizzuto, N. Denisenko, J. Z.Y. Jiang, W. Kononenko, Mingming Yang, D. Mendoza, Y. S. Zhu, R. Van Berg, S. Repond, Pm Tuts, Vasken Hagopian, R. Zeller, S. Protopopescu, A. S. Ito, F. Goozen, Andrew Brandt, C. Yoshikawa, R. Engelmann, Liu Chen, V. Glebov, D. Buchholz, A. Para, Marvin Johnson, I. Manning, Victor Daniel Elvira, H. Greenlee, Philippe Eberhard, Welathantri Gd Dharmaratna, E. A. Kozlovsky, Robert Hirosky, Sergey Denisov, Bobby Samir Acharya, H. A. Neal, Andrew White, A. Baden, S. H. Aronson, Kaushik De, Howard Gordon, M. Abolins, A. Zinchenko, W. Smart, D. Norman, M. Goforth, N. Bozko, S. Youssef, W. Y. Chen, L. Markosky, P. Mooney, R. J. Madaras, T. L. Geld, A. Klatchko, T. Heuring, H. E. Fisk, D. Nešić, Y. K. Que, V. Oguri, Heng Xu, G. C. Blazey, M. Sosebee, H. T. Diehl, H. Haggerty, Paolo Franzini, V. S. Narasimham, D. P. Eartly, Sharon Hagopian, Yu. Pischalnikov, J. McKinley, D. Hedin, A. Zieminski, C. Cretsinger, S. Lökös, J. F. Bartlett, Ivan Kotov, J. F. Glicenstein, J. Balderston, M. Strovink, K. Krempetz, V. A. Bezzubov, J. Ellison, A. K.A. Maciel, Raymond Brock, Boaz Klima, Z. Wolf, Meenakshi Narain, A. Peryshkin, R. P. Smith, R. L. McCarthy, Sissel Hansen, A. A. Mayorov, P. Grudberg, J. Yang, B. Daniels, Renkai Li, Srinivasan Rajagopalan, A. Suhanov, M. R. Krishnaswamy, F. Nang, Thomas Ferbel, Dan Green, T. Regan, T. Behnke, V. Burtovoy, L. T. Kerth, Michael Shupe, J. A. Wightman, Gilvan Alves, C. S. Gao, J. Sculli, M. Diesburg, A. Efimov, Kenneth Johns, A. Milder, Juliet Lee-Franzini, R. Huson, C. R. Johnson, C. Murphy, Gregory R Snow, D. Denisov, K. Bazizi, V. M. Podstavkov, S. Willis, M. Pang, L. Sawyer, Harrison Prosper, Sergey Chekulaev, S. Fahey, V. I. Kochetkov, Sylvain Tisserant, Peter Nemethy, R. Stephens, B. May, J. Kourlas, A. V. Kozelov, C. Klopfenstein, J. D. Taylor, Allan G Clark, Bruno Mansoulie, I. Adam, P. Rubinov, M. Paterno, N. K. Mondal, S. Stampke, F. Lobkowicz, L. Z. Wang, David Cutts, K. W. Merritt, R. L. Dixon, A. L. Spadafora, W. A. Wenzel, Michael Rijssenbeek, G. T. Mulholland, R. E. Lanou, S. H. Ahn, M. Fatyga, Allen Mincer, D. Stewart, M. Vaz, J. Thompson, Yanwen Liu, S. Kanekal, D. A. Stoyanova, A. Zylberstejn, L. Lueking, J. S. Hoftun, O. Callot, M. L. Stevenson, J. M. Guida, Alexey Volkov, E. Malamud, J. M. Kohli, R. Partridge, Dhiman Chakraborty, G. Rahal-Callot, N. Amos, Quing Zhu, P. Yamin, S. Abachi, Orin I. Dahl, John Rutherfoord, J. Featherly, T. Huehn, M. F. Shea, D. Fein, M. Fortner, P. Laurens, D. Edmunds, J. Linnemann, Alberto Santoro, J. G.R. Lima, Y. H. Zhou, G. E. Forden, A. P. Heinson, Y. Xia, A. Kernan, R. E. Hall, S. Lami, S. Krzywdzinski, A. L. Read, R. Yamada, V. Riadovikov, A. Pluquet, P. Martin, A. Jonckheere, C. Yanagisawa, M. D. Peters, James C. Green, L. Oesch, W. Guryn, M. H.G. Souza, D. Lloyd-Owen, Greg Landsberg, B. I. Klochkov, J. M. Hauptman, Cecilia Elena Gerber, F. Borcherding, H. Piekarz, E. Oltman, Li Jingyuan, Vyacheslav Klyukhin, B. Gibbard, M. Tartaglia, Stephan Linn, N. Oshima, A. Smith, D. C. Wang, R. Madden, L. Rasmussen, Jinghong Chen, Peter W. Draper, Pushpalatha C Bhat, M. Mudan, A. Taketani, S.A. Kahn, M. Demarteau, R. E. Avery, W. G. Cobau, M. I. Martin, E. Flattum, Ph. Mangeot, A. Shkurenkov, C. H. Park, H. S. Mao, W. E. Cooper, N. Graf, J. Yu, M. V. S. Rao, M. Montag, Alexander Vorobiev, G. Álvarez, J. Kotcher, B. G. Pope, J. Teiger, R. D. Schamberger, J. T. White, A. Boehnlein, P. Z. Quintas, K. Hodel, and J. H. Christenson

Subjects
Physics, Nuclear and High Energy Physics, Physics::Instrumentation and Detectors, Detector, Tevatron, D0 experiment, law.invention, Nuclear physics, Transition radiation detector, Data acquisition, law, Hermetic detector, Physics::Accelerator Physics, High Energy Physics::Experiment, Fermilab, Collider, Instrumentation
Abstract

The DØ detector is a large general purpose detector for the study of short-distance phenomena in high energy antiproton-proton collisions, now in operation at the Fermilab Tevatron collider. The detector focusses upon the detection of electrons, muons, jets and missing transverse momentum. We describe the design and performance of the major elements of the detector, including the tracking chambers, transition radiation detector, liquid argon calorimetry and muon detection. The associated electronics, triggering systems and data acquisition systems are presented. The global mechanical, high voltage, and experiment monitoring and control systems which support the detector are described. We also discuss the design and implementation of software and software support systems that are specific to DØ. © 1994.

Published
1994

188. Technical design of a detector to be operated at the Superconducting Super Collider

Author

S. Segler, S. Kim, K. Amako, J.G. Jernigan, E. Erdos, M. O'Neille, D. Klokow, W. Nilsson, T. Tsuboyama, T. O'Halloran, M. Sivertz, James Nugent Bellinger, Barry Blumenfeld, I. Fujiwara, G. Baranko, R. G. Wagner, C. Hearty, H. Fujii, D. J. Summers, Jonathan Bagger, A. Elam, C. Caprio, Y. Watase, Kazumasa Miyano, R. Poling, G. Atlas, K. De, V. Myalkovsky, A.A. Omelyanenko, C.A. Corradi, J.D. Simpkins, T. K. Ohska, Philippe Eberhard, P. G. Estabrooks, M.R. Marcin, J. P. Pansart, M. Horoi, K. Tsukada, S. Kabe, T.A. Nunamaker, K. Gulamov, T. L. Watts, Kenneth J. Heller, M.E. Levi, R. W. Kadel, H. Sanders, N. Kanematsu, W. S. Toothacker, R. K. Plunkett, William S. Lockman, N. Tamura, Virgil E Barnes, G. Sullivan, D.T. Hackworth, J. Grunhaus, R. P. Thun, H. Grassman, M. Kawaguchi, R. Van Berg, Y. Chiba, J. Harmon, L. Nodulman, E. Gabathuler, T.A. Armstrong, R.L. Swensrud, S. Tkaczyk, Granville Ott, T. Emura, K. Yasuoka, Richard H. Milburn, D.I. Khubua, U. Nauenberg, R. McIlwain, H. Miyata, C. Foudas, J. T. White, D. Wu, Dixit, J. Orgeron, Sarah Catherine Eno, H.J. Krebs, Susumu Terada, T. Spassov, N.S. Amaglobeli, E.D. Minor, K. Kaneyuki, M. Pripstein, E. Peterson, G. Liang, G. Schultz, D. Blockus, J. Lackey, Tachishige Hirose, Wei-guo Li, B. Bonner, David Underwood, E. Surin, Y. Hoshi, A. Baden, M. Newcomer, K. Kondo, A. Alexa, R. E. Blair, Hui-shun Mao, David Miller, Vladimir Vinogradov, J. F. Patrick, V. J. Guarino, J. Grimson, J. J. Thaler, K. Ruddick, J. B. Dainton, Helmuth Spieler, N. N. Biswas, J. F. Martin, A. Dzierba, X. Lou, A. G. Clark, Hua-chuan Cui, A. Napier, De-qiang Huang, T.S. Yoon, A.N. Sinaev, G. G. Hanson, S.A. Gourlay, S.B. Kim, P. Le Du, M. Haney, R. N. Cahn, Y. Morita, H. M. Spinka, David E. Pellett, S. Ahmad, S.B. Gerasimov, E.N. Tsyganov, R. S. Orr, M. Nakamura, T. Iinuma, Alexander Malakhov, E.N. May, N.P. Johnson, W.Bruce Lowery, C.W. Glover, Na-ding Qi, M. Riddle, A.S. Vodopianov, Duncan Carlsmith, K. Denisenko, S. Kato, R.T. Hagstrom, J. J. Whitmore, Alan Sill, Y. Funayama, S. Godfrey, E. Barasch, A. Lim, D.W. Scherbarth, J. Hoff, B. Yuldashev, R.J. Wilkes, Leo Piilonen, Zhang Re Ju, Andrew Beretvas, A. Zinchenko, H. Courant, J. Proudfoot, J. A. Kadyk, Burke, John F. Gunion, T. J. Phillips, Larry D. Gladney, Mark Campbell, B. Foster, K. Masuda, G.P. Yeh, H. Hammack, T. Shinkawa, Tai-jie Wang, H.J. Stredde, Stephen Maxfield, Andris Skuja, Richard Nickerson, A.E. Senner, A.M. Dvornik, G.S. Gao, Liu Hong Tao, M. Mangano, C.Y. Chang, C. Campagneri, V.T. Sidorov, Robert P. Ely, M. Mishina, W. Courtney, Shuichi Kunori, S. Geer, J.A. Kulchitsky, R. Kephart, J. Mann, T. Miyachi, J. M. Hauptman, L. VanderHave, E. Poole, E. Shibata, T.B.W. Kirk, G. Punzi, R.W. Fast, K. A. Johns, A. Baumbaugh, G. H. Trilling, Richard C. Jared, P. Border, A. H. Ball, S. L. Shapiro, H. Ikeda, F.R. Huson, Hikaru Kawai, A. Menzione, G.J. Luste, D. Passuello, A. Yuldashev, A. Manabe, David H. Adams, G. Mutchler, G. Kramer, B. Byslma, M. Franklin, C. Petrascu, Motomasa Daigo, W.R. Edwards, Donald E. Groom, B. Martin, J. Millaud, J. Kilmer, Wen-xiu Gao, N. Ujiie, A. Seiden, J. Rasson, S.R. Hahn, Osamu Sasaki, P. Kesten, S. Worley, Giovanni Bellettini, R. M. Harris, R.G. Alsmiller, T. Kaneko, Richard Gray, John Perry Cumalat, S. N. White, D. Cutts, J. Wiss, R.C. Chaney, Deepa Thomas, G. J. Feldman, S. Miyashita, M. Pentia, Randy Ruchti, R. Kikuchi, Yasuo Doi, S. C. Loken, A. P.T. Palounek, Neville Harnew, Jacobo Konigsberg, J. Skeens, J. C. Freeman, Sau Lan Wu, E. Engels, H. O. Ogren, T. Gerace, W.D. Walker, A. Lee, P. Schlabach, S. Behrends, E.A. Matyushevsky, G. A. Beck, K. Hasegawa, M. Marshak, D. Nitz, Patrick Slattery, A. Srefanik, M. Strovink, Wu-guang Yan, A. B. Wicklund, B. Lu, J. Ellison, Robert Stone, J. Yoh, Ta Romanowski, T. Müller, G. Pauletta, J. Bailey, Henry Lubatti, Y. Asano, H. Yoshida, G. T. Zorn, D. Finley, A. Murakami, T. J. V. Bowcock, A.L. Litke, R. C. Ball, R. Heifetz, T Yoshida, A. Semenov, G. Alley, B. A. Barnett, L. E. Price, Vasken Hagopian, I. P. J. Shipsey, C.W. Einolf, C. Gross-Pilcher, C. Pfeiffer, N. Giokaris, Y. Unno, M. Hoff, R. J. Wilson, J. DeWitt, Lou Bing Qiao, B. Buddle, E. Barsotti, W. McGinley, G.A. Smith, J. Park, S. Kashigin, S. Zhang, M. C. Edwards, J.A. Goodman, J. Hylen, A. Para, J. Armitage, A.V. Shabunov, Geoffrey Smith, Craig Blocker, R. Foster, M. Asai, H.U. Bengtsson, M.J. Longo, Wei-ren Zhao, G. W. Foster, Yu.S. Pakhmutov, David B. Cline, T. Nash, M. Seman, R. Hubbard, D. Shuman, H. Iwasaki, Kevin Einsweiler, R.V. Tsenov, T. P. Ryan, Ph. Martin, W.A. Wenzel, R. Partridge, E. Spencer, E. E. Schmidt, Tom Zimmerman, Kurtis F Johnson, Greg P Heath, D. Hutchinson, Y. Takaiwa, M. Chiba, L. Dittert, Y. Teramoto, I. Gaines, J.K. Walker, M. Turcotte, S.K. Park, E.H. Thorndike, Hans-Joachim Ziock, R.A. Lewis, Nicholas John Hadley, N. Hill, Bruce Denby, O. Milgrome, He Yu Ming, G.H. Trilling, Daniel Pitzl, D.E. Dorfan, Lai Chu Xi, A. Liss, William T. Ford, A. Maki, P. Limon, John Huth, A.C. Amatuni, R. L. Talaga, H. Goldberg, H. A. Neal, D. Bintinger, G.H. Grayer, J. Godfrey, N. Denisenko, A. Vacchi, A. Bodek, M. Corden, Y. Zhang, W. A. Mann, V. Simaitis, D. Marschik, A. Bischoff, L.A. Vasilev, G.V. Velev, G. S. Abrams, Jason Lea Oliver, Tomiyoshi Haruyama, J. E. Elias, P. H. Fisher, P. Rankin, C. Wendt, W.R. Frisken, A. R. Erwin, R. Downing, B. P. Roe, A. T. Laasanen, A.D. Kovalenko, R.H. Wands, N. Zhuravlev, Pavel P. Povinec, T. Inagaki, Jay Hauser, J. Bishop, Norman Gee, W. Thur, B. Hubbard, W. J. Robertson, R. Koniuk, K. Niwa, Y. Sakai, A. Barbaro-Galtieri, M. D. Corcoran, S. Kan, Yue-hua Zhou, J. Mahall, K. Turdaliev, S. Kleinfelder, G. A. Snow, K. Ogawa, A. J. Lankford, I. Nakano, A. Mukerjee, L. Holloway, D. Wolfe, H.W.K. Cheung, R. Yarema, K. Abe, Z. Guzik, M. Alimov, H. D. Wahl, H. Johnstad, G. W. Brandenburg, S.H. Oh, A.B. Iordanov, K. Takikawa, H.J. Trost, M.M. Wu, Yu.V. Zanevsky, T. Ohsugi, S. Inaba, H.Richard Gustafson, J.D. Prentice, Liu-sheng Zheng, J. Ernwein, H. Mes, M. J. Shochet, J. Spalek, L. Ristori, L.W. Mo, James G. Smith, A. T. Goshaw, M. G. D. Gilchriese, J.M. Toms, V. Kaprior, T. Droege, B.Y. Oh, S.F. Heppelmann, W. Pope, E.J. Anderson, R. Loveless, Kazuhiko Hara, L. Rosenberg, T. Devlin, Liu Song Qiu, Y. Gotra, Jay Roberts, P. Kapcio, W. D. Shephard, V.I. Astakhov, Stephen Wimpenny, Vaclav Vrba, A.M. Chuenko, K. Hashim, Y. Arai, C. Grozis, Ol. Barkan, S. Errede, D.P. Coupal, M. Finger, A. J.R. Weinstein, F. Rondeaux, A. D. Bross, D. R. Rust, D.D. Reeder, J. Siegrist, Y.A. Panebratsev, R. D. Field, R. Vidal, N. Madden, E.J. Fenyves, C. C. Buchanan, Petroff, T.Y. Ling, T. Zhao, S. Hong, Y. Watanabe, M. Binkley, H. Yuta, S. Kobayashi, I. Karliner, L. E. Kirsch, T. Okusawa, G.A. Vartapetian, P. F. Shepard, S. Margulies, J. Kuzminski, K. Nishikawa, Yu.S. Gusar, M. Shioden, Dg Stairs, V. Smirnov, R. J. Hollebeek, R. G. Kellogg, D. Chrisman, R.C. Weidenbach, Aharon Levy, W. E. Slater, J. R. Bensinger, Alan Garfinkel, D.R. Nygren, P. McIntyre, B. B. Brabson, A. Pak, J. S. Brown, D. K. Hasell, F. Lobkowicz, J. Cooper, T. Takahashi, I. A. Tyapkin, J. Cherwinka, F.V. Levchanovsky, M. Takano, Lawrence W. Jones, W.A. Rowe, D.I. Hubua, Masato Higuchi, Catherine Newman-Holmes, D.S. Koltick, Paul Sheldon, Yuichi Kubota, K. Sliwa, David Bailey, B.V. Batyunya, J. Piekarz, I.V. Puzynin, R.Michael Barnett, P. Job, K.W. Hartman, B. Chiladze, Nikolai Zimine, M. Miller, D. Amidei, R. J. Cashmore, T. Nakamura, A. Jawahery, Y. Takada, M. Derrick, Ian Hinchliffe, P. Bonamy, D. Vandergriff, Gerald Oakham, L. S. Durkin, Edmond L. Berger, A.N. Sisakian, Yoshihiko Nagashima, Henry J. Frisch, Kozo Miyake, I.F. Kolpakov, Shigeru Odaka, K. Ragan, H.E. Miettinen, R. Hamatsu, Hartmut Sadrozinski, T.L. Ekenberg, S. Galeotti, V.P. Kenney, N. M. Cason, L. Bartoszek, Y.Y. Minamihara, T. Kondo, Dan Pantea, Hui-ling Ni, Marjorie Shapiro, B. Wheeler, J. Bibby, S. Homma, E. Sadowski, S. Sugimoto, S. Mori, A. Gautier, P. Sinervo, A. Hasan, V.M. Golovatyuk, K. Arisaka, H. Sakamoto, W. H. Smith, F.S. Alsmiller, J. W. Dawson, Y. N. Kharzheev, M. J. Losty, T.L. Moore, L.G. Moroz, T. Kafka, S. M. Fisher, T. Tanimori, R. Bernstein, T.H. Fields, N.B. Maksimenko, F Abe, F. Krivan, D. P. Eartly, R. Salukvadze, R. L. Wagner, J.F. Arens, K. Goulianos, Yu.F. Lomakin, K. O'Shaughnessy, Franco Bedeschi, M. Contreras, K. Takahashi, D.A. Roberts, E. Wente, D. Moore, J. Solomon, C.D. Cantrell, Yu.A. Budagov, A. Fry, A. Khaneles, P. Melese, Sh. Aliev, S. Kanda, Yoshiji Yasu, F. Luehring, R. Stanek, J. W. Chapman, H. H. Williams, C. Haber, Junichi Kanzaki, M. Atac, Trevor Collins, W. Williams, D.R. Green, M. Noumachi, D.G. Fong, R.J. Davisson, Yu.V. Ilyin, Y. Fukui, T. Humanic, J. A. J. Matthews, C. A. Heusch, S. Mani, F. Feyzi, R. Amendolia, G. Appolinari, A.I. Dokshin, Yang Ji Xiang, C.J. Kenney, A. Yamamoto, Peter Strmen, Ming-han Ye, V.H. Areti, C.Y. Fu, Sherwood Parker, P. F. Derwent, A. Nunez, Roger Rusack, Yao Shu De, and J. Nasiatka

Subjects
Physics, Schedule, Calorimeter (particle physics), Physics::Instrumentation and Detectors, business.industry, Detector, Electrical engineering, Tracking system, Superconducting magnet, Superconducting Super Collider, Nuclear physics, Data acquisition, Physics::Accelerator Physics, High Energy Physics::Experiment, Electronics, business
Abstract

This report discusses the following topics on the Soleoidal Detector Collaboration: Summary and overview of the detector; physics and detector requirements; central tracking system; superconducting magnet; calorimetry; muon system; electronics; online computing; offline computing; safety; experimental facilities; installation; test and calibration beam plan; and cost and schedule summary.

Published
1992
Full Text
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189. [The diagnosis and treatment of respiratory and circulatory disorders in the acute period of gunshot chest wounds]

Author

I G, Leshchenko, V N, Denisenko, and V Iu, Shanin

Subjects
Adult, Warfare, Military Personnel, Adolescent, Thoracic Injuries, Cardiovascular Diseases, Acute Disease, Respiratory Tract Diseases, Afghanistan, Humans, Wounds, Gunshot, USSR
Abstract

Principle and method for gravity estimation of wounds, as well as the efficiency index of treatment of breathing and circulatory disorders in patients with chest gunshot injuries were elaborated on the basis of integral body rheography with mathematical modelling. The application of this method gives the possibility to make an opportune estimation and prognostication of the gravity of clinic outcome of chest gunshot injuries, choose the most rational scheme of treatment of breathing and circulatory disorders. The application of integral body rheography increases the quality of secondary surgical care at the phases of medical evacuation.

Published
1992

190. Relativistic resonance traveling-wave tube with tunable oscillation frequency

Author

A. V. Savel’ev, V. V. Yastrebov, A. N. Denisenko, E. B. Abubakirov, and E. I. Soluyanov

Subjects
Physics, Waveguide (electromagnetism), Range (particle radiation), Physics and Astronomy (miscellaneous), Oscillation, business.industry, Physics::Optics, Resonance, Traveling-wave tube, law.invention, Vackář oscillator, Optics, law, Tube (fluid conveyance), Backward-wave oscillator, business
Abstract

A high-power microwave oscillator is realized experimentally, employing a relativistic traveling-wave tube with a feedback circuit closed by tunable Bragg waveguide reflectors. A gigawatt-pulse power level is attained in the oscillator in the 3-cm wavelength range, which is maintained when the carrier frequency is tuned in a range of about 5%.

Published
2000
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191. [Standardization of miral levels in the soil]

Author

N F, Motuzinskiĭ, L N, Denisenko, R V, Korol', and E A, Katruk

Subjects
Insecticides, Escherichia coli, Actinomyces, Soil Pollutants, Organothiophosphorus Compounds, Maximum Allowable Concentration, In Vitro Techniques, Moldova, Soil Microbiology
Abstract

On the basis of results of studies on experimental substantiation of MAC for miral in soil it has been found out, that the sub-threshold miral amounts according to the water-migrational, air-migrational, translocational and general sanitary indices of harmfulness equal 0.03, 3, 0.03 and 0.15 mg/kg respectively. Therefore, water-migrational and translocational indices are the limiting indices of harmfulness for miral. 0.03 mg per 1 kg of absolutely dry soil is recommended for miral MAC according to the acting substance.

Published
1991

192. [Contact radiotherapy in rheumatoid lesions of the knee joint using Au-198]

Author

B Ia, Drozdovskiĭ, V N, Ivanov, A I, Ikonnikov, O N, Denisenko, L F, Ivanova, and L S, Borisova

Subjects
Arthritis, Rheumatoid, Gold Radioisotopes, Knee Joint, Evaluation Studies as Topic, Brachytherapy, Synovial Fluid, Synovial Membrane, Humans, Radiotherapy Dosage, Retrospective Studies
Abstract

An instrumental-calculation method of assessment of an absorbed dose of radiation in the synovial tissue of the knee joint in radionuclide therapy with 198Au using directly measured topometric parameters was used for patients with rheumatoid arthritis. A group of 294 knee joint of 138 patients was considered by way of a retrospective analysis. Dosimetric indices in all cases (except stage IV arthritis) showed values which were not contrary to clinical assessment of the patients: status after therapy.

Published
1991

194. Jet energy resolution of the SDC detector

Author

H. Iso, A. Para, D. Green, G.P. Yeh, N. Denisenko, K. Denisenko, W. Wu, and A. Beretvas

Subjects
Nuclear physics, Physics, Particle decay, Jet (fluid), Particle physics, Detector, High Energy Physics::Experiment, Elementary particle, Particle detector, Energy (signal processing), Prime (order theory), Boson
Abstract

We have answered the PAC question ( Demonstrate the jet energy resolution of your proposed detector by studying decays Z {yields} jet + jet and Z{prime} {yields} jet + jet, M{sub Z{prime}} = 1 TeV.'') using a general program called SSCSIM. This program is a tool for investigating simple questions involving the relations between detector parameters and physics capabilities of a detector. A different package called ANLSIM developed by our colleagues at Argonne has also been used to answer this question. The results as expected are very similar. In this note we will try to document our procedures. Our tentative conclusion from this study is that physics induced effects, out-of-cone fluctuations and underlying event fluctuations, dominate the resolution. Pushing the detector performance to the limits of technology improves the effective resolution by at most 20%. 20 refs., 6 figs., 5 tabs.

Published
1990
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195. [Substantiation of cyclophos MPEL in the soil]

Author

N F, Motuzinskiĭ, L N, Denisenko, A N, Stroĭ, R V, Korol', and V G, Mereniuk

Subjects
Air Pollutants, Drug Stability, Polyphosphates, Soil Pollutants, Drug Resistance, Microbial, Maximum Allowable Concentration, Moldova, Ukraine, Soil Microbiology, Water Pollutants, Chemical
Abstract

On the basis of studies aimed at the substantiation of MAC for cyclophos in soil it was established, that subthreshold amounts of cyclophos according to the water-migration and air-migration indexes of harmfulness equal 0.03 mg per 1 kg of absolutely dry soil, according to the general sanitary index--0.1 mg/kg. Since cyclophos destruction period in plants is relatively short (8 days), there is no danger of translocation of the pesticide from soil in amounts exceeding the maximum allowable level for cyclophos in food stuffs. The pesticide migration in the system soil-plant was not determined. The water migration and air-migration indexes are the limiting indexes of harmfulness for cyclophos. 0.03 mg/kg is recommended as the maximum allowable concentration of cyclophos in soil.

Published
1990

196. Heat shock translational control in cell-free system

Author

Oleg N. Denisenko and Oleg Bronislavovich Yarchuk

Subjects
Hot Temperature, Reticulocytes, Base Sequence, Cell-Free System, Free system, Molecular Sequence Data, General Medicine, Biology, Microbiology, Molecular biology, Shock (mechanics), Heat shock protein, Protein Biosynthesis, Biophysics, Animals, Base sequence, Amino Acid Sequence, RNA, Messenger, Rabbits, Codon, Molecular Biology, Heat-Shock Proteins
Published
1990

198. [Development of the method of ultrasound topometry of the thyroid gland and computer programs in the planning of radioactive iodine therapy]

Author

V N, Ivanov, V S, Parshin, L F, Ivanova, O N, Denisenko, and B Ia, Drozdovskiĭ

Subjects
Iodine Radioisotopes, Radiotherapy Planning, Computer-Assisted, Computer Graphics, Thyroid Gland, Humans, Thyroid Neoplasms, Algorithms, Radiotherapy, Computer-Assisted, Software, Ultrasonography
Abstract

The paper is concerned with the problem of stereological volumenometry applied to the problems of ultrasound topometry of the thyroid. The organ surfaces are tightened on the basis of information obtained from echotomographic films using a method of cubic spline-interpolation, parametric function setting and methods of computer graphics. Images of sections can be obtained with an arbitrary step and an angle of inclination to the organ longitudinal axis. The main sources of errors of the method were estimated, and their numeric values were given.

Published
1990

199. [Technical methodologic aspects of clinical dosimetry in radionuclide therapy]

Author

O N, Denisenko, V N, Ivanov, B Ia, Drozdovskiĭ, Iu P, Nikulin, E G, Tiatte, L F, Ivanova, and V S, Parshin

Subjects
Radioisotopes, Radiotherapy Dosage, Equipment Design, Middle Aged, Absorption, Iodine Radioisotopes, Thyrotoxicosis, Humans, Female, Radiometry, Radionuclide Imaging, Technology, Radiologic, Mathematics, Ultrasonography
Abstract

The paper is devoted to the solution of problems related to clinical dosimetry in radiation therapy with open radionuclides, i.e. technical methodological problems of measurement of an absorbed therapeutic dose of radiation in targets in volume distribution of a radionuclide. The developed methods and means of measurement include a large activity radiometer for measuring therapeutic and diagnostic activities, a topometric ultrasound unit (Aloka) and software. The main features of the method were illustrated on a clinical example of the assessment of an absorbed therapeutic dose of 131I radiation in thyroid tissue during therapy of patients with thyrotoxicosis. The accuracy of the method was assessed.

Published
1990

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