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923 results on '"Amino acids -- Health aspects"'

152. Peptide Mapping of Monoclonal Antibodies and Antibody--Drug Conjugates Using Micro--Pillar Array Columns Combined with Mass Spectrometry

Author

Sandra, Koen, Vandenbussche, Jonathan, Vandenheede, Isabel, Claerebout, Bo, Beeck, Jeff Op De, Jacobs, Paul, Malsche, Wim De, Desmet, Gert, and Sandra, Pat

Subjects
Spectroscopy -- Health aspects, Monoclonal antibodies -- Health aspects, Peptides -- Health aspects, Amino acids -- Health aspects, Chromatography -- Health aspects, Biopharmaceuticals -- Health aspects, Pharmaceutical industry -- Health aspects, Chemistry, Science and technology, Remicade (Medication) -- Health aspects, Kadcyla (Medication) -- Health aspects, Adcetris (Medication) -- Health aspects, Herceptin (Medication) -- Health aspects
Abstract

Monoclonal antibodies are becoming a core aspect of the pharmaceutical industry. Together with a huge therapeutic potential, these molecules come with a structural complexity that drives state-of-the-art chromatography and mass spectrometry (MS) to its limits. This article discusses the use of micro-pillar array columns in combination with mass spectrometry for peptide mapping of monoclonal antibodies (mAbs) and antibody--drug conjugates (ADCs). Micro-pillar array columns are produced by a lithographic etching process creating a perfectly ordered separation bed on a silicon chip. As a result of the order existing in these columns, peak dispersion is minimized and highly efficient peptide maps are generated, providing enormous structural detail. Using examples from the author's laboratory, the performance of these columns is illustrated., The discovery of monoclonal antibodies (mAbs) in the 1970s and the realization of their therapeutic potential in the following decades has been a key milestone in medicine (1-3). Today, over [...]

Published
2018

153. Reports Summarize Medicinal Chemistry Study Results from Shionogi Pharmaceutical Research Center (Discovery of 2-sulfinyl-diazabicyclooctane Derivatives, Potential Oral Beta-lactamase Inhibitors for Infections Caused By Serine ...)

Subjects
Beta lactamases -- Health aspects, Sulbactam -- Health aspects, Amino acids -- Health aspects, Bacterial infections -- Health aspects, Infection -- Health aspects, Physical fitness -- Health aspects, Health
Abstract

2021 AUG 14 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity, Fitness & Wellness Week -- New research on Health and Medicine - Medicinal Chemistry is the subject [...]

Published
2021

154. The Supply Of A Drug For Medical Use (amino Acid Ketoanalogs)

Subjects
Amino acids -- Health aspects, Business, international
Abstract

Tenders are invited for the supply of a drug for medical use (amino acid ketoanalogs) Major organization : MINISTRY OF ECONOMIC DEVELOPMENT OF THE REPUBLIC OF ALTAI Address : 649000, [...]

Published
2023

161. Delivery Of A Drug For The Medical Use Of Amino Acid For Parenteral Nutrition Other Drugs fat Emulsions For Parenteral Nutrition Of Dextrose Minerals

Subjects
Dextrose -- Health aspects, Nutrition -- Health aspects, Amino acids -- Health aspects, Glucose -- Health aspects, Business, international
Abstract

Tenders are invited for delivery of a drug for the medical use of amino acid for parenteral nutrition other drugs fat emulsions for parenteral nutrition of dextrose minerals Major organization [...]

Published
2023

162. The Supply Of A Drug For Medical Use With Mnn Amino Acids For Parenteral Nutrition Other Drugs fat Emulsions For Parenteral Nutrition Of Mineral Dextrose For The Needs Of The Cokb Named After Korolev E

Subjects
Dextrose -- Health aspects, Nutrition -- Health aspects, Amino acids -- Health aspects, Glucose -- Health aspects, Business, international
Abstract

Tenders are invited for the supply of a drug for medical use with mnn amino acids for parenteral nutrition other drugs fat emulsions for parenteral nutrition of mineral dextrose for [...]

Published
2023

163. Delivery Of A Drug For Medical Use Of Amino Acid Ketoanalogs

Subjects
Amino acids -- Health aspects, Business, international
Abstract

Tenders are invited for delivery of a drug for medical use of amino acid ketoanalogs Major organization : COMMITTEE FOR THE REGULATION OF THE CONTRACT SYSTEM IN THE FIELD OF [...]

Published
2023

165. The Supply Of A Drug For Medical Use With Mnn Ketoanalogs Of Amino Acids To Provide Citizens Entitled To Receive State Social Assistance In The Form Of A Set Of Social Services (registry Number 230181)

Subjects
Social service -- Health aspects, Welfare -- Health aspects, Amino acids -- Health aspects, Business, international
Abstract

Tenders are invited for the supply of a drug for medical use with mnn ketoanalogs of amino acids to provide citizens entitled to receive state social assistance in the form [...]

Published
2023

169. Delivery Of Drugs For Medical Use: Amino Acid Ketoanalogs

Subjects
Amino acids -- Health aspects, Business, international
Abstract

Tenders are invited for delivery of drugs for medical use: amino acid ketoanalogs Major organization : STATE STATE INSTITUTION OF THE KRASNODAR TERRITORY 'DIRECTORATE OF STATE PROCUREMENT' Address : Russian [...]

Published
2023

170. The Drug Of Amino Acid Ketoanalogs For Medical Use

Subjects
Amino acids -- Health aspects, Business, international
Abstract

Tenders are invited for the drug of amino acid ketoanalogs for medical use by prescription for drugs to ensure certain categories of citizens entitled to preferential medicinal security, in accordance [...]

Published
2023

173. Findings from China Agricultural University Update Knowledge of Food Science and Human Wellness (The Amino Acids Differences In Epitopes May Promote the Different Allergenicity of Ovomucoid Derived From Hen Eggs and Quail Eggs)

Subjects
Antigenic determinants -- Health aspects, Quails -- Health aspects, Amino acids -- Health aspects, Health
Abstract

2023 MAY 5 (NewsRx) -- By a News Reporter-Staff News Editor at Health & Medicine Week -- Investigators discuss new findings in Diet and Nutrition - Food Science and Human [...]

Published
2023

175. Ea-no.-23049|22 electronic Auction For The Right To Conclude A Contract For The Supply Of A Drug For The Medical Use Of Amino Acid For Parenteral Nutrition. Other Drugs fat Emulsions For Parenteral Nutrition Of Mineral Dextrose

Subjects
Dextrose -- Health aspects, Auctions -- Health aspects, Nutrition -- Health aspects, Amino acids -- Health aspects, Glucose -- Health aspects, Contract agreement, Business, international
Abstract

Tenders are invited for ea-no.-23049/22 electronic auction for the right to conclude a contract for the supply of a drug for the medical use of amino acid for parenteral nutrition. [...]

Published
2022

179. Provision For The Drug For Medical Use Of Amino Acid Ketoanalogs

Subjects
Amino acids -- Health aspects, Business, international
Abstract

Tenders are invited for 2022-16996_ the drug for medical use of amino acid ketoanalogs Major organization : OFFICE FOR THE REGULATION OF A CONTRACT SYSTEM IN THE FIELD OF PROCUREMENT [...]

Published
2022

182. 2023-no. 2788 Supply Of Drugs For Medical Use: Amino Acid Ketoanalogs

Subjects
Amino acids -- Health aspects, Business, international
Abstract

Tenders are invited for 2023-no. 2788 supply of drugs for medical use: amino acid ketoanalogs Major organization : STATE STATE INSTITUTION OF THE NOVOSIBIRSK REGION 'OFFICE OF THE CONTRACT SYSTEM' [...]

Published
2022

186. The Purchase Of Drugs For Medical Use With The Aim Of Preferential Drug Support Of Certain Categories Of Citizens, Including For The Execution Of Judicial Acts In The Oryol Region In 2023. Ketoanalogs Of Amino Acids (zhnvlp)

Subjects
Amino acids -- Health aspects, Business, international
Abstract

Tenders are invited for the purchase of drugs for medical use with the aim of preferential drug support of certain categories of citizens, including for the execution of judicial acts [...]

Published
2022

187. 2022-16436 Supply Of A Drug For The Medical Use Of Amino Acid For Parenteral Nutrition Other Drugs fat Emulsions For Parenteral Nutrition Of Mineral Dextrose

Subjects
Dextrose -- Health aspects, Nutrition -- Health aspects, Amino acids -- Health aspects, Glucose -- Health aspects, Business, international
Abstract

Tenders are invited for 2022-16436 supply of a drug for the medical use of amino acid for parenteral nutrition other drugs fat emulsions for parenteral nutrition of mineral dextrose Major [...]

Published
2022

188. Purchase Of Drugs For Medical Use (mnn Recombinant Protein Containing An Amino Acid Sequence Of Staphylokinase)

Subjects
Group purchasing organizations -- Health aspects, Amino acids -- Health aspects, Recombinant proteins -- Health aspects, Business, international
Abstract

Tenders are invited for purchase of drugs for medical use (mnn recombinant protein containing an amino acid sequence of staphylokinase) Major organization : STATE STATE INSTITUTION OF THE REPUBLIC OF [...]

Published
2022

190. Delivery Of Drugs For Medical Use (mnn: Amino Acids For Parenteral Nutrition. Other Drugs fat Emulsions For Parenteral Nutrition Of Mineral Dextrose )

Subjects
Dextrose -- Health aspects, Nutrition -- Health aspects, Drugs -- Health aspects, Amino acids -- Health aspects, Glucose -- Health aspects, Business, international
Abstract

Tenders are invited for delivery of drugs for medical use (mnn: amino acids for parenteral nutrition. other drugs fat emulsions for parenteral nutrition of mineral dextrose ) Major organization : [...]

Published
2022

191. 2022-16120_ Supply Of The Drug For The Medical Use Of Amino Acid For Parenteral Nutrition. Other Drugs fat Emulsions For Parenteral Nutrition Of Mineral Dextrose

Subjects
Dextrose -- Health aspects, Nutrition -- Health aspects, Amino acids -- Health aspects, Glucose -- Health aspects, Business, international
Abstract

Tenders are invited for 2022-16120_ supply of the drug for the medical use of amino acid for parenteral nutrition. other drugs fat emulsions for parenteral nutrition of mineral dextrose Major [...]

Published
2022

192. The Purchase Of A Drug For Medical Use ketoanalogs Of Amino Acids To Provide Citizens Entitled To Receive State Social Assistance In The Form Of A Set Of Social Services In Accordance With Federal Law Of July 17, 1999 No. 178- on State Social Assista

Subjects
Social service -- Health aspects, Welfare -- Health aspects, Group purchasing organizations -- Health aspects, Amino acids -- Health aspects, Business, international
Abstract

Tenders are invited for the purchase of a drug for medical use ketoanalogs of amino acids to provide citizens entitled to receive state social assistance in the form of a [...]

Published
2022

195. 2022-14267_ The Drug For Medical Use Of Amino Acid Ketoanalogs

Subjects
Amino acids -- Health aspects, Business, international
Abstract

Tenders are invited for 2022-14267_ the drug for medical use of amino acid ketoanalogs Major organization : OFFICE FOR THE REGULATION OF A CONTRACT SYSTEM IN THE FIELD OF PROCUREMENT [...]

Published
2022

196. 2022-14650|Delivery Of A Drug For Medical Use Of Mnn 'amino Acids For Parenteral Nutrition. Other Drugs fat Emulsions For Parenteral Nutrition Of Mineral Dextrose '

Subjects
Dextrose -- Health aspects, Nutrition -- Health aspects, Amino acids -- Health aspects, Glucose -- Health aspects, Business, international
Abstract

Tenders are invited for 2022-14650 / delivery of a drug for medical use of mnn 'amino acids for parenteral nutrition. other drugs fat emulsions for parenteral nutrition of mineral dextrose [...]

Published
2022

197. The Purchase Of A Drug For Medical Use (mnn: Ketoanalogs Of Amino Acids) To Ensure Certain Categories Of Citizens Permanently Residing In The Territory Of The Vladimir Region, When Providing Outpatient Assistance For Their Social Security In Accordance Wi

Subjects
Social service -- Health aspects, Social security -- Health aspects, Amino acids -- Health aspects, Business, international
Abstract

Tenders are invited for the purchase of a drug for medical use (mnn: ketoanalogs of amino acids) to ensure certain categories of citizens permanently residing in the territory of the [...]

Published
2022

199. The Supply Of Drugs For Medical Use (recombinant Protein Containing An Amino Acid Sequence Of Staphylokinase) In 2023 (auction 26)

Subjects
Auctions -- Health aspects, Amino acids -- Health aspects, Recombinant proteins -- Health aspects, Business, international
Abstract

Tenders are invited for the supply of drugs for medical use (recombinant protein containing an amino acid sequence of staphylokinase) in 2023 (auction 26). Major organization : STATE BUDGETARY INSTITUTION [...]

Published
2022

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