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1,129 results on '"Eckert R"'

158. Characterization of 35 new cases with four different MPLW515 mutations and essential thrombocytosis or primary myelofibrosis

Author

Schnittger, S., primary, Bacher, U., additional, Haferlach, C., additional, Beelen, D., additional, Bojko, P., additional, Burkle, D., additional, Dengler, R., additional, Distelrath, A., additional, Eckart, M., additional, Eckert, R., additional, Fries, S., additional, Knoblich, J., additional, Kochling, G., additional, Laubenstein, H.-P., additional, Petrides, P., additional, Planker, M., additional, Pihusch, R., additional, Weide, R., additional, Kern, W., additional, and Haferlach, T., additional

Published
2009
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159. Sulfur dioxide at the Venus cloud tops, 1978-1986

Author

Esposito, Larry W, Copley, M, Eckert, R, Gates, L, and Stewart, A. I. F

Subjects
Lunar And Planetary Exploration
Abstract

Ultraviolet spectroscopy from the Pioneer Venus Orbiter shows a decline in the cloud top abundance of SO2 from about 100 ppb to about 10 ppb in the period 1978-1986. A consistent decline in polar haze has occurred over the same period, with the correlation coefficient between these two observables of r = 0.8. Star calibrations determine the instrument sensitivity to within 10 percent which rules out the possibility that this is an instrumental effect. Systematic errors could increase the SO2 abundance to twice the inferred values in later orbits. Tracking of SO2 features and power spectral analysis give rotation periods for the longer-lived features of 3.6-5.2 days, consistent with cloud-tracked winds observed at other wavelengths. The behavior of SO2 and polar haze can be plausibly explained by episodic injection of SO2 into the cloud top regions, for example, by active volcanism.

Published
1988

170. Hermetically sealed motion transmitter

Author

Eckert, R. L

Subjects
Machinery
Abstract

Transmitter allows transmission of rotational or single planar arc motion through hermetically sealed chamber without use of dynamic seals or complex mechanisms. Device may interest pressure vessel designers and those who need to isolate equipment from a hostile environment.

Published
1971

174. Involvement of RARRES3 in the regulation of Wnt proteins acylation and signaling activities in human breast cancer cells.

Author

Hsu, T-H, Jiang, S-Y, Chan, W-L, Eckert, R L, Scharadin, T M, and Chang, T-C

Subjects
NEOPLASTIC cell transformation, GROWTH factors, BREAST cancer, MESENCHYMAL stem cells, EPITHELIAL cells
Abstract

The Wnt/β-catenin signaling pathway has emerged as a key regulator of complex biological processes, such as embryonic development, cell proliferation, cell fate decision and tumorigenesis. Recent studies have shown that the deregulation of Wnt/β-catenin signaling is frequently observed and leads to abnormal cell growth in human breast cancer cells. In this study, we identified a novel regulatory mechanism of Wnt/β-catenin signaling through RARRES3 that targets and modulates the acylation status of Wnt proteins and co-receptor low-density lipoprotein receptor-related protein 6, resulting in the suppression of epithelial-mesenchymal transition and cancer stem cell properties. Mutation of the conserved active site residues of RARRES3 indicates that RARRES3 serves as an acyl protein thioesterase that tethers its target proteins and modulates their acylation status. Furthermore, the functions of p53 in cell proliferation and Wnt/β-catenin signaling are significantly associated with the induction of RARRES3. Thus our findings provide a new insight into the molecular link between p53, protein acylation and Wnt/β-catenin signaling whereby RARRES3 plays a pivotal role in modulating the acylation status of signaling proteins. [ABSTRACT FROM AUTHOR]

Published
2015
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176. Towards a new gliadin reference material–isolation and characterisation

Author

van Eckert, R., primary, Berghofer, E., additional, Ciclitira, P.J., additional, Chirdo, F., additional, Denery-Papini, S., additional, Ellis, H.J., additional, Ferranti, P., additional, Goodwin, P., additional, Immer, U., additional, Mamone, G., additional, Méndez, E., additional, Mothes, T., additional, Novalin, S., additional, Osman, A., additional, Rumbo, M., additional, Stern, M., additional, Thorell, L., additional, Whim, A., additional, and Wieser, H., additional

Published
2006
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177. Splenopentin (DAc-SP5)--influence on engraftment and graft-vs-host reaction after non-H-2 bone marrow transplantation in mice

Author

J. Maciejewski, Rüdiger von Baehr, Eckert R, Diezel W, Hans-Dieter Volk, H. Weber, and Forner K

Subjects
Bone marrow transplantation, medicine.drug_class, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Graft versus host reaction, Graft vs Host Reaction, Thymopoietins, Immunostimulant, Mice, Endocrinology, Internal Medicine, medicine, Animals, Bone Marrow Transplantation, Chemotherapy, Mice, Inbred BALB C, Mice, Inbred C3H, business.industry, H-2 Antigens, General Medicine, Peptide Fragments, Transplantation, medicine.anatomical_structure, Mice, Inbred DBA, Splenopentin, Immunology, Mice, Inbred CBA, Bone marrow, business
Abstract

The influence of DAc-SP5 on engraftment and graft-vs-host reaction (GVHR) was studied in different non-H-2 strain combinations. The engraftment was more or less enhanced in every case, whereas the situation in the GVHR was completely different. In one case splenopentin did not influence the course of the GVHR so much, in a second case the symptoms of the GVHR were completely abolished, and in a third case the GVHR was dramatically enhanced up to a great mortality. Therefore, before application of DAc-SP5 to the bone marrow transplantation in humans in order to improve the engraftment, parameters have to be found which allow an exact prediction about the influence of splenopentin on the GVHR in each single case.

Published
1990

178. [Change in the central relationship conflict by short-term therapy]

Author

Kächele H, Dorothee Dengler, Eckert R, and Schnekenburger S

Subjects
Adult, Conflict, Psychological, Male, Humans, Psychotherapy, Brief, Transference, Psychology, Female, Interpersonal Relations, Object Attachment, Psychoanalytic Therapy
Abstract

Luborskys method of the Core Conflictual Relationship Theme is introduced as a reliable tool for studying structural aspects of transference. The change of the components of the CCRT induced by a short term psychotherapy is described and discussed in terms of its clinical significance.

Published
1990

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