151. Association of spontaneous labor onset with neonatal outcomes in pregnancies with fetal gastroschisis: A retrospective cohort analysis.
- Author
-
Osmundo Junior, Gilmar de Souza, Mohamed, Samirah Hosney Mahmoud, Nishie, Estela Naomi, Tannuri, Ana Cristina Aoun, Gibelli, Maria Augusta Bento Cicaroni, Francisco, Rossana Pulcineli Vieira, and Brizot, Maria de Lourdes
- Subjects
CHILDBIRTH ,PREGNANCY complications ,GASTROSCHISIS ,COHORT analysis ,ULTRASONIC imaging ,DIAGNOSIS of neonatal diseases ,INTESTINAL injuries ,DELIVERY (Obstetrics) ,FETAL ultrasonic imaging ,GESTATIONAL age ,NEONATAL diseases ,PREMATURE infants ,INTESTINES ,LABOR (Obstetrics) ,EVALUATION of medical care ,PREGNANCY ,PRENATAL care ,RETROSPECTIVE studies - Abstract
Introduction: The present study aims to investigate the association of spontaneous labor onset with neonatal outcomes in pregnancies with fetal gastroschisis. The secondary goal was to evaluate the association between ultrasound markers and labor onset in pregnancies with fetal gastroschisis.Material and Methods: A retrospective analysis was performed for 207 pregnancies with fetal gastroschisis between 2005 and 2017. Patients were followed according to a strict protocol involving ultrasound scans and routine evaluations of fetal biophysical profile parameters and intra- and extra-abdominal bowel diameters. Labor, delivery and neonatal records were reviewed. The neonatal outcomes were complex gastroschisis, staged surgical closure of the abdominal defect, short bowel syndrome, time on mechanical ventilation, time to full enteral feeding and necrotizing enterocolitis.Results: Spontaneous labor onset was associated with complex gastroschisis (30.7% vs 6.8%, P = 0.002) and short bowel syndrome (13.2% vs none, P = 0.013) in cases with spontaneous preterm delivery compared with the indicated preterm deliveries. Spontaneous labor onset was associated with a longer time on mechanical ventilation for term and preterm newborns. Associations were not observed between ultrasound markers and spontaneous labor onset.Conclusions: Spontaneous labor onset in pregnancies with fetal gastroschisis was associated with adverse neonatal outcomes, particularly in those born preterm. [ABSTRACT FROM AUTHOR]- Published
- 2019
- Full Text
- View/download PDF