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Daily growth of the follicles before ovulation and the changes of the endometrium after ovulation were recorded in 16 spontaneous menstrual cycles by the ultrasonic and biochemical measurements. The mean diameter of the dominant follicle was 20 mm before ovulation, the mean volume 3.0 ml, and the growth rate of the follicles 1-3 mm/24 h. Ovulation occurred within 24 h of the luteinizing hormone peak and within 48 hours of the blood estrogen peak. The fact that the blood progesterone levels were higher on the day of the LH peak indicated that luteinization of the dominant follicles had already occurred prior to ovulation. Sonographic criteria of the endometrical tissue were obtained after the serial observation. According to the different sonographic appearances, the secretory phase of the endometrial tissue was divided into the early secretory phase, the middle secretory phase and the late secretory phase. The sonographic characterization of the endometrial tissue in the different phases as well as the thickness of the endometrium during the cycles were described. The clinical usefulness of the criteria of the different phases was to evaluate the subsequent luteal function, and facilitate the clinical management of the infertile women. The study confirms that ultrasound can provide a reliable measure in monitoring the follicular growth and ovulation, and observing the morphological changes of the endometrial tissue during the secretory phase. Thus the in vivo differentiation of the endometrial tissue during the secretory phase could be studied non-invasively by means of the ultrasound tissue characterization.

The therapeutic effect and laboratory finding in the treatment of 288 cases of ischemic cerebrovascular disease with PSS were analysed. Positive therapeutic response to PSS in this series of cases was obtained in 92.0% and 62.2% of the treated cases showed excellent results. Effects in the treated patients were better than in the controls. The laboratory findings showed that PSS had obvious anticoagulant effect and decreased blood viscosity and serum contents of lipids. The results of animal experiments showed that PSS had the action of blood dilution, lowering blood viscosity and ameliorating hypercoagulation. PSS was considered to be a prospective, useful drug to prevent and treat ischemic cerebrovascular disease.