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152. Remote Monitoring for Implantable Defibrillators: A Nationwide Survey in Italy

Author

Luzi, Mario, De Simone, Antonio, Leoni, Loira, Amellone, Claudia, Pisanò, Ennio, Favale, Stefano, Iacoviello, Massimo, Luise, Raffaele, Bongiorni, Maria Grazia, Stabile, Giuseppe, La Rocca, Vincenzo, Folino, Franco, Capucci, Alessandro, D'Onofrio, Antonio, Accardi, Francesco, Valsecchi, Sergio, and Buia, Gianfranco

Subjects
Computer applications to medicine. Medical informatics, R858-859.7, Medical technology, R855-855.5
Abstract

BackgroundRemote monitoring (RM) permits home interrogation of implantable cardioverter defibrillator (ICD) and provides an alternative option to frequent in-person visits. ObjectiveThe Italia-RM survey aimed to investigate the current practice of ICD follow-up in Italy and to evaluate the adoption and routine use of RM. MethodsAn ad hoc questionnaire on RM adoption and resource use during in-clinic and remote follow-up sessions was completed in 206 Italian implanting centers. ResultsThe frequency of routine in-clinic ICD visits was 2 per year in 158/206 (76.7%) centers, 3 per year in 37/206 (18.0%) centers, and 4 per year in 10/206 (4.9%) centers. Follow-up examinations were performed by a cardiologist in 203/206 (98.5%) centers, and by more than one health care worker in 184/206 (89.3%) centers. There were 137/206 (66.5%) responding centers that had already adopted an RM system, the proportion of ICD patients remotely monitored being 15% for single- and dual-chamber ICD and 20% for cardiac resynchronization therapy ICD. Remote ICD interrogations were scheduled every 3 months, and were performed by a cardiologist in 124/137 (90.5%) centers. After the adoption of RM, the mean time between in-clinic visits increased from 5 (SD 1) to 8 (SD 3) months (P

Published
2013
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154. Biomarkers in Cardiorenal Syndrome

Author

Goffredo, Giovanni, primary, Barone, Roberta, additional, Di Terlizzi, Vito, additional, Correale, Michele, additional, Brunetti, Natale Daniele, additional, and Iacoviello, Massimo, additional

Published
2021
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155. The Evolving Phenotypes of Cardiovascular Disease during COVID-19 Pandemic

Author

Correale, Michele, primary, Croella, Francesca, additional, Leopizzi, Alessandra, additional, Mazzeo, Pietro, additional, Tricarico, Lucia, additional, Mallardi, Adriana, additional, Fortunato, Martino, additional, Magnesa, Michele, additional, Ceci, Vincenzo, additional, Puteo, Alessandra, additional, Iacoviello, Massimo, additional, Di Biase, Matteo, additional, and Brunetti, Natale Daniele, additional

Published
2021
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157. Multivessel spontaneous coronary artery dissection and Crohn's disease

Author

Corbo, Maria Delia, primary, Centola, Antonio, additional, Fortunato, Martino, additional, Mazzeo, Pietro, additional, Vitale, Enrica, additional, Della Monica, Davide, additional, Magnesa, Michele, additional, Ieva, Riccardo, additional, Cuculo, Andrea, additional, Iacoviello, Massimo, additional, and Brunetti, Natale Daniele, additional

Published
2021
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158. Eligibility of outpatients with chronic heart failure for sodium–glucose co‐transporter‐2 inhibitors

Author

Angelini, Gianmarco, primary, Albanese, Miriam, additional, Ursi, Raffaella, additional, Lisi, Francesco, additional, Bellino, Maria Consiglia, additional, Amato, Luca, additional, Gioia, Margherita Ilaria, additional, Parisi, Giuseppe, additional, Brunetti, Natale Daniele, additional, Piazzolla, Giuseppina, additional, Ciccone, Marco Matteo, additional, and Iacoviello, Massimo, additional

Published
2021
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178. Would You Prescribe Mobile Health Apps for Heart Failure Self-care? An Integrated Review of Commercially Available Mobile Technology for Heart Failure Patients

Author

Mortara, Andrea, primary, Vaira, Lucia, additional, Palmieri, Vittorio, additional, Iacoviello, Massimo, additional, Battistoni, Ilaria, additional, Iacovoni, Attilio, additional, Macera, Francesca, additional, Pasqualucci, Daniele, additional, Bochicchio, Mario, additional, and De Maria, Renata, additional

Published
2020
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180. Thyroid Disorders and Prognosis in Chronic Heart Failure: A Long-Term Follow-Up Study

Author

Iacoviello, Massimo, primary, Parisi, Giuseppe, additional, Gioia, Margherita I., additional, Grande, Dario, additional, Rizzo, Caterina, additional, Guida, Pietro, additional, Lisi, Francesco, additional, Giagulli, Vito A., additional, Licchelli, Brunella, additional, Di Serio, Francesca, additional, Guastamacchia, Edoardo, additional, and Triggiani, Vincenzo, additional

Published
2020
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181. MULTIPLE HORMONAL AND METABOLIC DEFICIENCY SYNDROME REDUCES SURVIVAL IN CHRONIC HEART FAILURE: THE TOSCA REGISTRY

Author

Marra, Alberto, primary, Bossone, Eduardo, additional, Salzano, Andrea, additional, Iacoviello, Massimo, additional, Rengo, Giuseppe, additional, Cacciatore, Francesco, additional, Limongelli, Giuseppe, additional, Perticone, Francesco, additional, Perrone-Filardi, Pasquale, additional, Mancini, Antonio, additional, Volterrani, Maurizio, additional, Vriz, Olga, additional, D'Assante, Roberta, additional, Suzuki, Toru, additional, Ventura, Hector, additional, and Cittadini, Antonio, additional

Published
2020
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182. Metformin: Up to Date

Author

Sciannimanico, Silvia, primary, Grimaldi, Franco, additional, Vescini, Fabio, additional, De Pergola, Giovanni, additional, Iacoviello, Massimo, additional, Licchelli, Brunella, additional, Guastamacchia, Edoardo, additional, Giagulli, Vito A., additional, and Triggiani, Vincenzo, additional

Published
2020
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189. The PONTE (PDTA FOR INTEGRATED FOLLOW-UP TERRITORY HOSPITAL OF THE PATIENT WITH CARDIAC HEARTFAILURE) (BRIDGE) Heart Failure project: increased adherence to guideline-recommended therapies through web-based shared clinical database

Author

De Gennaro, Luisa, Iacoviello, Massimo, Donadeo, Vittorio, Ruggiero, Massimo, Brunetti, Natale Daniele, and Caldarola, Pasquale

Abstract

The aim of this study was to evaluate the effects on the adherence of drug prescription to the guideline recommendations of a chronic care model based on the close interaction between hospital and local healthcare district cardiologists through a shared web-based database. From 2018 to 2021, patients hospitalized for an episode of acute decompensated heart failure (HF) (de novoor worsening) in cardiology wards from the healthcare district of Bari, Italy, were enrolled. The follow-up programme was based on a first visit after discharge within 1 month; patients were therefore addressed to the local health district cardiologist outpatient clinics when not requiring further invasive investigations and haemodynamically stable and followed-up with at least one visit every 6 months. In order to share in-hospital patients’ data with outpatient clinics, at discharge, they were entered in a web-based database accessible for all cardiologists and centres participating in the Ponte Project. The group of patients affected by HF with reduced ejection fraction (HFrEF) were considered for the analyses. Drug prescription rates at 1-year follow-up were analysed as endpoint, as well as the re-admission for HF worsening. Out of 1200 HF patients enrolled in the project until December 2021, 56% were affected by HFrEF. At 1-year follow-up, 91% of patients were assuming beta-blockers, 86% mineralocorticoid receptor antagonists, 98% angiotensin-converting enzyme inhibitors/angiotensin receptor antagonists/neprilysin angiotensin receptor antagonists, and 13% ARNI. Compared to patients enrolled before 2020, ARNI prescription increased in 2021 (60% vs. 13%, respectively, P< 0.001). In 30% of patients, ARNI were prescribed before hospital discharge. Furthermore, in 10% of the population (most diabetics), sodium-glucose cotransporter 2 inhibitors were also prescribed. The implementation of the PONTE project was associated with an improved adherence to guidelines recommendations.

Published
2022
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190. Prognostic role of neoplastic markers in Takotsubo syndrome.

Author

Santoro, Francesco, Zimotti, Tecla, Mallardi, Adriana, Leopizzi, Alessandra, Vitale, Enrica, Tarantino, Nicola, Ferraretti, Armando, Solimando, Antonio Giovanni, Racanelli, Vito, Iacoviello, Massimo, Cannone, Michele, Di Biase, Matteo, and Brunetti, Natale Daniele

Subjects
TAKOTSUBO cardiomyopathy, NEOPLASTIC cell transformation, CARCINOEMBRYONIC antigen, HEART failure risk factors, FOLLOW-up studies (Medicine), BLOOD serum analysis
Abstract

Takotsubo syndrome (TTS) is an acute heart failure syndrome with significant rates of in and out-of-hospital mayor cardiac adverse events (MACE). To evaluate the possible role of neoplastic biomarkers [CA-15.3, CA-19.9 and Carcinoembryonic Antigen (CEA)] as prognostic marker at short- and long-term follow-up in subjects with TTS. Ninety consecutive subjects with TTS were enrolled and followed for a median of 3 years. Circulating levels of CA-15.3, CA-19.9 and CEA were evaluated at admission, after 72 h and at discharge. Incidence of MACE during hospitalization and follow-up were recorded. Forty-three (46%) patients experienced MACE during hospitalization. These patients had increased admission levels of CEA (4.3 ± 6.2 vs. 2.2 ± 1.5 ng/mL, p = 0.03). CEA levels were higher in subjects with in-hospital MACE. At long term follow-up, CEA and CA-19.9 levels were associated with increased risk of death (log rank p < 0.01, HR = 5.3, 95% CI 1.9–14.8, HR = 7.8 95% CI 2.4–25.1, respectively, p < 0.01). At multivariable analysis levels higher than median of CEA, CA-19.9 or both were independent predictors of death at long term (Log-Rank p < 0.01). Having both CEA and CA-19.9 levels above median (> 2 ng/mL, > 8 UI/mL respectively) was associated with an increased risk of mortality of 11.8 (95% CI 2.6–52.5, p = 0.001) at follow up. Increased CEA and CA-19.9 serum levels are associated with higher risk of death at long-term follow up in patients with TTS. CEA serum levels are correlated with in-hospital MACE. [ABSTRACT FROM AUTHOR]

Published
2021
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198. Association between high Gal-3 serum levels and worsening of renal function in chronic heart failure outpatients

Author

Iacoviello, Massimo, primary, Di Serio, Francesca, additional, Rizzo, Caterina, additional, Leone, Marta, additional, Grande, Dario, additional, Guida, Pietro, additional, Gioia, Margherita Ilaria, additional, Parisi, Giuseppe, additional, Leopizzi, Tiziana, additional, Caldarola, Pasquale, additional, Ciccone, Marco Matteo, additional, and Gesualdo, Loreto, additional

Published
2019
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