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154. Are the Effects of Age and Gender Changing the Personal Values of Japanese Executives?

Author

Giacomino, Don, Fujita, Atsushi, and Johnson, Thomas M.

Subjects
Executives -- Psychological aspects, Values -- Testing -- Psychological aspects, Business, general, Business, Testing, Psychological aspects
Abstract

There is ample justification for research on personal values in Japan and on comparisons between Japanese and American values. Japan is a major part of the world economy and has [...]

Published
1999

156. Open architecture as an enabler for FORCEnet Cruise Missile Defense

Author

Camacho, Juan G., Guest, Lawrence F., Hernandez, Belen M., Johnson, Thomas M., Kang, Alan H., Le, Giang T., MacGillivray, Brian J., Ngo, Tu K., Norman, Kyle B., Tomei, Franklin, Green, John M., and Systems Engineering (SE)

Subjects
ComputerApplications_COMPUTERSINOTHERSYSTEMS
Abstract

Advancements in missile technology have made cruise missile capability available worldwide. Current US naval weapon systems lack full interoperability across multiple platforms and full integration of detection, control, and engagement processes against incoming targets. The key to defeating future threats to our military assets is in gaining additional reaction time. This can be accomplished by leveraging collective sensor detection data throughout the battlespace, utilizing the FORCEnet data resources to evaluate the threat, and engaging the threat with a tiered defense. The objective of this capstone project is to address the above issues through the use of Open Architecture (OA) within a FORCEnet environment. This report focuses on the development of a conceptual architecture for Cruise Missile Defense (CMD) that combines FORCEnet architecture requirements with Program Executive Office of Integrated Warfare Systems (PEO IWS)'s OA functional architecture technical requirements. Further, this conceptual architecture is compared with PEO IWS's functional architecture via a series of systems engineering diagrams. These diagrams culminate in a simulation model that analyzes and determines the validity of the conceptual architecture. Results from the simulation model show that the conceptual architecture performed significantly better than PEO IWS's. These results are attributed to the addition of a re-engagement loop called Observe-Orient-Decide-Act (OODA). http://archive.org/details/openrchitectures109456930

Published
2007

161. Temporospatial Angiogenisis-Associated Gene Expression Profiles in Rat Ischemic Skin Flaps.

Author

Johnson, Thomas M., Toussaint-Barrett, Esra, and Pizarro, Jose M.

Subjects
*VASCULAR endothelial growth factors, *GENE expression, *NEOVASCULARIZATION, *SURGICAL flaps, *ISCHEMIA
Abstract

Objectives: Emerging therapies designed to improve soft tissue flap survival include the use of angiogenic factors. However, endogenous expression patterns for these factors have not been characterized. The purpose of this study was to identify spatial and temporal variations in expression patterns of angiogenesis-associated genes in ischemic rat skin flaps. Study Design: This is an observational animal study characterizing spatial and temporal angiogenesis associated gene expression patterns in rat ischemic skin flaps. Methods: Dorsal skin flaps were created on 15 male Sprague-Dawley rats. The flap tissue was harvested and sectioned at 1, 3, or 7 days postsurgery. Total RNA was isolated, amplified, labeled with biotin, and hybridized to microarrays containing probes for 113 angiogenesis-associated genes. Microarray analysis revealed unique spatial and temporal patterns with statistically significant gene modulation over the length of the flap (P<.05). Results: The molecular analysis performed in this study correlates with the hemodynamic profile previously published. Expression patterns associated with blood flow were markedly different from patterns associated with stasis and avascularity. Conclusions: To our knowledge, this study is the first to characterize endogenous spatial and temporal angiogenesisassociated gene expression in rat ischemic skin flaps. Further characterization of expression patterns may allow clinicians to differentiate ischemic tissue that may be rescued via pharmacological or surgical intervention from tissue destined to succumb. Additionally, comparison of the expression profiles observed in this study with profiles generated from pharmacologically treated rats may suggest mechanisms for enhanced healing. [ABSTRACT FROM AUTHOR]

Published
2017

162. How do Kenyan orphan girls experience less meaningful lives and how much does it matter for 'health'?

Author

Goodman, Michael, Johnson, Thomas, Guillot-Wright, Shannon, Porter, Katherine, Keiser, Philip, Gitari, Stanley, Goodman, Michael L, Johnson, Thomas M, Porter, Katherine Ackerman, and Keiser, Philip H

Subjects
ORPHANS, QUALITY of life, CHILDREN'S health, CHILD nutrition, CONDUCT of life, MENTAL health, ORPHANAGES, MEDICAL care standards, SOCIAL support, CROSS-sectional method, PSYCHOLOGY
Abstract

Background: Currently, 2.5 million orphaned children are living in Kenya and 56 million orphaned children are living across sub-Saharan Africa. No empirical research has investigated meaningfulness of life among this population, and few studies provide perspectives on the life-course consequences of losing a parent during childhood.Methods: In this study, we assess life meaningfulness in cross section of Kenyan women (n = 1974) in a semi-rural area of the country (Meru County) collected during June 2015. We used two sets of mediation analyses to assess (1) whether meaningfulness of life was lower among women who reported a parental death during their childhood, and how this association was mediated by social support, family functioning, school completion and HIV+ status of household, and (2) the extent to which lower subjective overall health among women who experienced orphanhood during childhood was mediated by less meaningfulness of life.Results: Women who experienced a parental death during childhood reported significantly less meaningful lives as adults. Lower social support and family functioning explained approximately 40% of the disparity. Women who experienced a parental death during childhood also had significantly worse subjective overall health, 18% of which was explained by lower meaningfulness of life.Conclusions: Further study on life meaningfulness and family capital in the context of the orphan crisis in sub-Saharan Africa is warranted, and required to promote equity across the lifespan. Policy efforts to support orphans and vulnerable children should target strengthening support networks and family functioning to optimize self-reported health outcomes. [ABSTRACT FROM AUTHOR]

Published
2017
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163. LexGrid Editor: Terminology Authoring for the Lexical Grid

Author

Johnson, Thomas M., Solbrig, Harold R., Armbrust, Daniel C., and Chute, Christopher G.

Subjects
Article
Abstract

The Lexical Grid (LexGrid) enables the integration of terminologies and ontologies through a common model, services, and tools. The LexGrid Editor is a prototype terminology authoring and maintenance tool designed for this environment. This demonstration will present an overview of the Editor’s functional capabilities in relation to technologies offered by the LexGrid platform. We will also demonstrate additional proof of concept work, such as integration of technology provided by the Protégé Ontology Management System.

Published
2005

166. Inappropriate p53 activation during development induces features of CHARGE syndrome

Author

Van Nostrand, Jeanine L., primary, Brady, Colleen A., additional, Jung, Heiyoun, additional, Fuentes, Daniel R., additional, Kozak, Margaret M., additional, Johnson, Thomas M., additional, Lin, Chieh-Yu, additional, Lin, Chien-Jung, additional, Swiderski, Donald L., additional, Vogel, Hannes, additional, Bernstein, Jonathan A., additional, Attié-Bitach, Tania, additional, Chang, Ching-Pin, additional, Wysocka, Joanna, additional, Martin, Donna M., additional, and Attardi, Laura D., additional

Published
2014
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169. Isotopic evidence for reduction of anthropogenic hexavalent chromium in Los Alamos National Laboratory groundwater

Author

Heikoop, Jeffrey M., primary, Johnson, Thomas M., additional, Birdsell, Kay H., additional, Longmire, Patrick, additional, Hickmott, Donald D., additional, Jacobs, Elaine P., additional, Broxton, David E., additional, Katzman, Danny, additional, Vesselinov, Velimir V., additional, Ding, Mei, additional, Vaniman, David T., additional, Reneau, Steven L., additional, Goering, Tim J., additional, Glessner, Justin, additional, and Basu, Anirban, additional

Published
2014
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171. Evidence for oxygenic photosynthesis half a billion years before the Great Oxidation Event

Author

Planavsky, Noah J., primary, Asael, Dan, additional, Hofmann, Axel, additional, Reinhard, Christopher T., additional, Lalonde, Stefan V., additional, Knudsen, Andrew, additional, Wang, Xiangli, additional, Ossa Ossa, Frantz, additional, Pecoits, Ernesto, additional, Smith, Albertus J. B., additional, Beukes, Nicolas J., additional, Bekker, Andrey, additional, Johnson, Thomas M., additional, Konhauser, Kurt O., additional, Lyons, Timothy W., additional, and Rouxel, Olivier J., additional

Published
2014
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173. Abstract IA4: Deconstructing p53 pathways in vivo

Author

Brady, Colleen A., primary, Broz, Daniela Kenzelmann, additional, Jiang, Dadi, additional, Mello, Stephano Spano, additional, Bieging, Kathryn, additional, Johnson, Thomas M., additional, Jarvis, Leslie A., additional, Kozak, Margaret M., additional, Basak, Shashwati, additional, and Attardi, Laura D., additional

Published
2013
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174. Groundwater

Author

Johnson, Thomas M., Roback, Robert C., McLing, Travis L., Bullen, Thomas D., DePaolo, Donald J., Doughty, Christine, Hunt, Randall J., Smith, Robert W., Cecil, L. DeWayne, and Murrell, Michael T.

Published
2000

186. Selenium as paleo-oceanographic proxy: A first assessment

Author

Mitchell, Kristen, primary, Mason, Paul R.D., additional, Van Cappellen, Philippe, additional, Johnson, Thomas M., additional, Gill, Benjamin C., additional, Owens, Jeremy D., additional, Diaz, Julia, additional, Ingall, Ellery D., additional, Reichart, Gert-Jan, additional, and Lyons, Timothy W., additional

Published
2012
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188. Archaeological Investigation of the New Geneva Pottery Waster/Loading Dock Site (36FA404), New Geneva, Fayette County, Pennsylvania

Author

Catts, Wade P., McCarthy, John P., and Johnson, Thomas M.

Subjects
New Geneva, Pennsylania, Pennsylvania (State / Territory), Grays Landing Lock and Dam, 36FA91, Collections Management, Monongahela River, Pennsylvania, 36FA404, Heritage Management
Abstract

Archeological investigations were conducted at 36FA404, the New Geneva Pottery Waster/Loading Dock Site. Field work consisted of both manually and mechanically excavated test units and trenches. Portions of the waster dump used by the New Geneva potters in the final two decades of the nineteenth century and into the early years of the twentieth century were excavated on Lot 167. Excavations on Lot 166 recovered artifacts associated with the Arthur Robbins’ pottery (circa 1907-1914). The artifacts were used as backfill for railroad construction. Along the Monongahela River shore a buried in situ deposit of ceramics was found and appears to date, like the deposits on Lot 167, from the final twenty years of the nineteenth century and into the first decade of the twentieth century. No documentary or archeological evidence was found indicating that a wharf or dock was present at 36FA404. Archeological evidence of the location of Ford Street was discovered in one of the excavation units, and a drain-like feature was found running parallel to the street. The road was used in the movement of pottery between the kilns and the Monongahela River. Over 66,000 artifacts were recovered from the current and previous investigations conducted at the site. Diagnostic and non-diagnostic stoneware and redware sherds, along with significant amounts of kiln furniture and misfired ceramics were found throughout the site, as well as small amounts of non-pottery related artifacts, such as glass containers, refined ceramics, nails, bone, spikes, and leather. Brick, slag,and coal in abundance were also recovered. The archeological and historical evidence has yielded data related to the production and transport of New Geneva stoneware. Historical records suggest that the upper Monongahela River potteries produced a somewhat limited range of vessel types, but may have been known for the large capacity jars and chums they manufactured. Later potters at the site produced predominantly jug forms, and the archeological record contained numerous examples of these vessels. The distribution of New Geneva stonewares seems to have been throughout the local region, and into the Ohio and Mississippi River valleys. By the end of the nineteenth century, as production failed to keep up with mechanized pottery factories located in the vicinity of Pittsburgh, the New Geneva potters apparently chose to produce for an increasingly local clientele. The New Geneva Pottery Waster/Loading Dock Site (36FA404) is recommended eligible for the National Register of Historic Places for the data it contains pertaining to the nineteenth and early twentieth century ceramic industry in New Geneva and due to its association with the New Geneva Pottery Site (36FA91) located across Route 166, and with the New Geneva Historic District, which is listed on the National Register of Historic Places. The site consists of the redeposited waster debris and secondary deposition resulting from the construction of the railroad overpass and incidental breakage during transport. Although the site is considered significant as an archeological resource contributing to the New Geneva Historic District, no additional archeological field work is recommended. Archeological investigations at the site recovered artifact assemblages and related data that constitute a sample of the range and variety of data available from the site. Accordingly, it is our opinion that the planned construction activities will have no adverse effect upon significant archeological resources at Site 36FA404.

Published
1995
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191. Distinct p53 Transcriptional Programs Dictate Acute DNA-Damage Responses and Tumor Suppression

Author

Brady, Colleen A., primary, Jiang, Dadi, additional, Mello, Stephano S., additional, Johnson, Thomas M., additional, Jarvis, Lesley A., additional, Kozak, Margaret M., additional, Broz, Daniela Kenzelmann, additional, Basak, Shashwati, additional, Park, Eunice J., additional, McLaughlin, Margaret E., additional, Karnezis, Anthony N., additional, and Attardi, Laura D., additional

Published
2011
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