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151. The host-parasite relationship in urinary tract infections

Author

L A, Hanson, S, Ahlstedt, U, Jodal, B, Kaijser, P, Larsson, G, Lidin-Janson, K, Lincoln, U, Lindberg, I, Mattsby, S, Olling, H, Peterson, and A, Sohl

Subjects
Antigens, Bacterial, Blood Bactericidal Activity, Bacteriuria, Pyelonephritis, Antibodies, Bacterial, Immunoglobulin A, Recurrence, Immunoglobulin G, Antibody Formation, Cystitis, Urinary Tract Infections, Escherichia coli, Humans, Female, Child, Escherichia coli Infections
Published
1975

152. Asymptomatic bacteriuria in schoolgirls. II. Differences in escherichia coli causing asymptomatic bacteriuria

Author

U, Lindberg, L A, Hanson, U, Jodal, G, Lidin-Janson, K, Lincoln, and S, Olling

Subjects
Antigens, Bacterial, Blood Bactericidal Activity, Adolescent, Bacteriuria, Pyelonephritis, Cystitis, Escherichia coli, Humans, Female, Child, Kidney, Escherichia coli Infections, ABO Blood-Group System
Abstract

Three hundred and forty-three E. coli strains isolated from the urine of patients with asymptomatic bacteriuria (ABU), symptomatic cystitis, or pyelonephritis were analysed with regard to O group distribution and sensitivity to the bactericidal effect of normal serum. Strains of O groups 1, 2, 4, 6, 7, 16, 18 and 75 were found in 31.3% in ABU, in 58.7% in cystitis and in 79.8% in pyelonephritis. Spontaneous agglutination was noted in 45.2% of ABU, 6.5% of cystitis and 1.7% of pyelonephritis strains. The strains from patients with ABU were significantly more sensitive to the bactericidal effect of normal serum than were those from patients with symptomatic urinary tract infection. In some patients with untreated ABU, changes in the characteristics of the urinary strains isolated were noted. The strains tended to become spontaneously agglutinating as well as more sensitive to the bactericidal activity of normal serum. The strains found in patients with ABU probably had an altered cell wall compared with those found in patients with symptomatic infections such that they produce fewer symptoms and possibly be less virulent.

Published
1975

154. Bacteriuria in pregnancy. Frequency and risk of acquisition

Author

K, Stenqvist, I, Dahlén-Nilsson, G, Lidin-Janson, K, Lincoln, A, Odén, S, Rignell, and C, Svanborg-Edén

Subjects
Adult, Sweden, Time Factors, Bacteriuria, Age Factors, Parity, Socioeconomic Factors, Pregnancy, Risk Factors, Urinary Tract Infections, Humans, Mass Screening, Female, Pregnancy Complications, Infectious
Abstract

A total of 3,254 pregnant women attending two antenatal clinics in Göteborg, Sweden, were screened for bacteriuria. The coverage of the pregnant population in the areas served by the two clinics was estimated to be 88%. Of the women who were registered at the two clinics, 99% took part in at least one screening; 71% were screened during each of the three intervals. The high frequency of screening of the women made it possible to estimate the risk of acquiring bacteriuria during pregnancy. This risk increased with the duration of pregnancy from 0.8% of bacteriuric women in the 12th gestational week to 1.93% at the end of pregnancy. The risk of onset of bacteriuria was highest between the ninth and 17th gestational weeks. The 16th gestational week was the optimal time for a single screening for bacteriuria calculated as the number of bacteriuria-free gestational weeks gained by treatment.

Published
1989

155. Chronic papillomatous dermatitis as a peristomal complication in conduit urinary diversion

Author

K. Lincoln, P. Wåhlén, Bo Bergman, H. Mobacken, G.-B. Löwhagen, and F. Knutson

Subjects
Adult, Male, medicine.medical_specialty, Time Factors, Adolescent, Urology, Urinary system, medicine.medical_treatment, Dermatitis, Urinary Diversion, Urine, Stoma (medicine), Colon, Sigmoid, Ileum, medicine, Humans, Postoperative Period, Aged, Skin, business.industry, Urinary diversion, Middle Aged, Dermatology, Surgery, Nephrology, Chronic Disease, Female, Ureter, Complication, business, Skin lesion, Follow-Up Studies
Abstract

In 76 patients with conduit urinary diversion, the skin in the stomal area was studied with regard to complications. No such complications had occurred in 39 cases. Superficial erosive dermatitis was present or had been a transient episode in 27 cases. The immediate peristomal area was found in ten cases to show a different type of complication. This was characterized by hyperplastic, papillomatous skin lesions of a chronic nature. A rubber urinary collecting device for long-term use had been fitted in nine of the ten patients, and none of them had a protruding nipple stoma. The clinical, microbiologic and histologic features of these hyperplastic lesions are described and aetiologic factors are discussed. Change to another type of collecting device was followed within three to six weeks by healing of the lesions.

Published
1979

158. Untreated asymptomatic bacteriuria in girls: II--Effect of phenoxymethylpenicillin and erythromycin given for intercurrent infections

Author

S. Hansson, Ulf Jodal, C Svanborg-Edén, and K. Lincoln

Subjects
medicine.medical_specialty, Adolescent, Bacteriuria, medicine.drug_class, Urinary system, Antibiotics, Tonsillitis, Electrophoresis, Starch Gel, Erythromycin, Urine, Cohort Studies, Internal medicine, medicine, Escherichia coli, Humans, Serotyping, Child, General Environmental Science, Retrospective Studies, business.industry, General Engineering, Drug Resistance, Microbial, General Medicine, medicine.disease, Surgery, Phenoxymethylpenicillin, Otitis Media, Otitis, Child, Preschool, General Earth and Planetary Sciences, Penicillin V, Female, medicine.symptom, business, medicine.drug, Research Article
Abstract

OBJECTIVE--To investigate the effects of phenoxymethylpenicillin and erythromycin on urinary isolates from patients with untreated asymptomatic bacteriuria. DESIGN--Retrospective study of subgroup of patients from cohort followed up till the end of 1986. SETTING--Outpatient clinic for children with urinary tract infections. PATIENTS--51 Girls aged under 15 with untreated asymptomatic bacteriuria. INTERVENTIONS--Before 1982 intercurrent infections (mostly tonsillitis or otitis) were treated with phenoxymethylpenicillin; after 1982 erythromycin treatment was preferred. END POINTS--Change of bacterial strain in urinary tract and symptomatic recurrences of disease. MEASUREMENTS AND MAIN RESULTS--Bacteria identified by serotype and electrophoretic type and compared before and after antibiotic treatment. Bacteriuria eradicated and replaced by new strains in most patients treated with phenoxymethylpenicillin, leading to symptomatic recurrences in about 15%. Conversely, patients given erythromycin rarely showed change in bacteriuria and none suffered symptomatic recurrence. CONCLUSIONS--In girls with untreated asymptomatic bacteriuria the use of phenoxymethylpenicillin for intercurrent infections may lead to a change of urinary bacteria and leave them at substantial risk of acute pyelonephritis. With erythromycin this risk is small (2/20 courses in this series).

Published
1989

159. Virulence-associated traits in Escherichia coli causing first and recurrent episodes of urinary tract infection in children with or without vesicoureteral reflux

Author

Hakon Leffler, Catharina Svanborg Edén, Mikael Hellström, H. Lomberg, K. Lincoln, and Ulf Jodal

Subjects
medicine.medical_specialty, Urinary system, Urology, Virulence, P Blood-Group System, Biology, medicine.disease_cause, Gastroenterology, Vesicoureteral reflux, Recurrence, Internal medicine, Recurrent pyelonephritis, medicine, Escherichia coli, Immunology and Allergy, Humans, Child, Vesico-Ureteral Reflux, Antigens, Bacterial, Pyelonephritis, Hemagglutination, Reflux, Adhesiveness, Infant, O Antigens, Hemolysin, biology.organism_classification, medicine.disease, Enterobacteriaceae, Infectious Diseases, Phenotype, Child, Preschool, Urinary Tract Infections, Female, Mannose
Abstract

Virulence-associated properties of 606 urinary isolates from 174 children with urinary tract infections were related to severity of infection and factors increasing host susceptibility, e.g., vesicoureteral reflux (grade II or higher) and P1 blood group phenotype. A high proportion of strains of Escherichia coli causing first or recurrent episodes of acute pyelonephritis in children without reflux expressed the previously noted high frequency of certain O antigens, resistance to serum killing, hemolysin production, and adhesive capacity. A significantly lower frequency of these traits and a higher frequency of non-E. coli were seen among isolates from children with pyelonephritis and reflux, cystitis, and asymptomatic bacteriuria. Reflux was thus found to be a determinant of the level of infection and of the bacterial properties required to produce pyelonephritis. Efforts aimed at preventing or treating urinary tract infection by interfering with "virulent" bacteria may be of less value in patients with recurrent pyelonephritis and reflux, who are most likely to develop renal scars.

Published
1984

163. Level diagnosis of symptomatic urinary tract infections in childhood

Author

U. Lindberg, K. Lincoln, and Ulf Jodal

Subjects
medicine.medical_specialty, Adolescent, Renal parenchyma, Urinary system, Urinary Bladder, Urine, Blood Sedimentation, Antibodies, Body Temperature, Kidney Concentrating Ability, Medical microbiology, Internal medicine, Cystitis, medicine, Escherichia coli, Humans, Child, biology, Pyelonephritis, business.industry, C-reactive protein, Urography, General Medicine, Surgery, C-Reactive Protein, Clinical diagnosis, Child, Preschool, Pediatrics, Perinatology and Child Health, Urinary Tract Infections, biology.protein, Antibody titration, Female, Ureter, business
Abstract

Jodal, U., Lindberg, U. and Lincoln, K. (Department of Paediatrics and Institute of Medical Microbiology, University of Goteborg, Goteborg, Sweden). Level diagnosis of symptomatic urinary tract infections in childhood. Acta Paediatr Scand, 64:201, 1975.–As no method for localization of urinary tract infection has been shown to be absolutely reliable, six procedures have been carried out simultaneously in 25 girls with acute symptomatic infections and the reliability of each method assessed. While clinical diagnosis of pyelonephritis or cystitis correlated well with the overall results of the battery of tests, the reliability of individual tests varied. Highest reliability was obtained with CRP determinations followed by antibody titration, sedimentation rate, and renal concentrating capacity. In the bladder washout test only 8 of the 14 patients with pyelonephritis had findings clearly indicating high infection. Intermittent or inadequate discharge of bacteria from the renal parenchyma is suggested as the major source for this inaccuracy. In fact, half of the 42 final washout specimens from girls with acute pyelonephritis contained less than 1 000 bacteria per ml, indicating that low numbers of organisms in ureteric urine is common in childhood pyelonephritis.

Published
1975

164. Residual concrements and urinary tract infection

Author

L. Grenabo, S. Pettersson, H. Hedelin, Jonas Hugosson, and K. Lincoln

Subjects
medicine.medical_specialty, medicine.drug_class, business.industry, Ureaplasma infection, Urinary system, fungi, Antibiotics, Urology, food and beverages, Prostatitis, Urine, Bacteriuria, urologic and male genital diseases, medicine.disease, medicine.disease_cause, female genital diseases and pregnancy complications, Concomitant, medicine, business, Ureaplasma urealyticum
Abstract

In patients with residual concrements after earlier stone operations and concomitant bacteriuria, the question can arise of whether the concrement is associated with the infection or not. If an infection is derived from a renal calculi, the bacteriuria is persistent, i.e. growth of the same bacteria in repeated cultures and relapse with the same bacteria after antibiotic treatment. However, other conditions can give persistent bacteriuria such as chronic prostatitis and infected bladder diverticulas. In certain patients it can also be difficult to evaluate whether the infection is persistent or recurrent. In Patients with persistent bacteriuria, the number of bacteria can vary and when low the bacteriuria can be interpreted as not significant if Kass’ criteria are applied (4). The micro-organisms can be difficult to detect, e.g. Ureaplasma urealyticum and Corynebacteria, and the result of the urinary culture can be falsely interpreted as negative. Patients with persistent bacteriuria may also have a temporary concomitant infection with other bacteria. If a small nongrowing residual concrement with a concomitant bacteriuria gives no other symptoms demanding surgery, it is important to establish whether the concrement is associated with the infection or not before surgery is recommended. If the infection can be traced to the concrement, it is believed necessary to remove the concrement to eradicate the infection. To distinguish upper from lower urinary tract infection by clinical symptoms only is a well-known difficulty (2,6). Ureteric catheterization after bladder washout and culturing of ureteric urine, according to Stamey (7), seems to be the most reliable method of doing this (1) and the only method which can give a side localization. During the last 5 years, we have used this method in 19 patients with small, nongroing, otherwise symptom-free residual concrements and bacteriuria or Ureaplasma infection, to select patients with high, i.e. stone-related infections.

Published
1988
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165. Bacteriuria in representative population samples of persons aged 72-79 years

Author

Gunnar R. Nordenstam, V. Sundh, K. Lincoln, C. Svanborg Edén, and Alvar Svanborg

Subjects
Male, medicine.medical_specialty, Pediatrics, Bacteriuria, Epidemiology, Population, Anti-Infective Agents, Urinary, Geographic population, Persistence (computer science), Recurrence, Internal medicine, Elderly population, medicine, Humans, Mass Screening, education, Escherichia coli Infections, Aged, Sweden, education.field_of_study, business.industry, medicine.disease, Female, business, Follow-Up Studies
Abstract

Screening for bacteriuria was performed between 1984 and 1988 in persons aged 72-79 years representative of the general population in Goteborg, Sweden. The frequency of bacteriuria (greater than or equal to 10(5)/ml) at a single screening was 6% and 16% at age 72 years and 6% and 14% at age 79 years for the screened men (n = 235 and 259) and women (n = 259 and 297), respectively. By repeated screening after one month and 30 months of those previously negative at age 72 years, an additional 4% and 3% of men and 3% and 7% of women with bacteriuria were detected. Bacteriuric persons were excluded from further screening and controlled by frequent cultures during several years, with careful monitoring of clinical interventions. The persistence of untreated bacteriuria was analyzed in relation to bacterial species and number in the untreated subgroup of bacteriuric individuals. Nine of 10 Escherichia coli (E. coli) with less than 10(6)/ml and 22/22 non-E. coli strains disappeared spontaneously. In contrast, 20/26 (77%, p less than 0.01) with greater than or equal to 10(6) E. coli/ml persisted. Of 17 persons with bacteriuria persisting at least 12 months, 16 were women and 16 had E. coli. Of 201 E. coli cultures obtained from this group, 94% had greater than or equal to 10(6)/ml, and 99% had greater than or equal to 5 x 10(5)/ml. The results indicate that screening for high counts (greater than 10(6)/ml) of E. coli most effectively detects persisting bacteriuria in the general elderly population.

Published
1989

166. The homogeneity of the faecal coliform flora of normal school-girls, characterized by serological and biochemical properties

Author

Hans Wedel, K. Lincoln, S. Olling, Bertil Kaijser, and G Lidin-Janson

Subjects
Microbiology (medical), Serotype, Bacteriological Techniques, Adolescent, Homogeneity (statistics), Immunology, General Medicine, Biology, Fecal culture, Serology, Microbiology, Fecal coliform, Feces, Phenotype, Escherichia coli, Immunology and Allergy, Humans, Female, Serotyping, Child
Abstract

The homogeneity of fecal coliform flora in 52 schoolgirls was studied by serotyping and biotyping 10 randomly selected colonies in one fecal culture from each child. Ninety-eight clones were identified and of these 52 were dominant and 46 were minor strains. The probability of including at least one isolate of the dominant clone in a small random sample of colonies was calculated to be 86% for one colony, 94% for 2, 97% for 3, 99% for 4, and 99.3% for 5 randomly selected colonies.

Published
1978

167. The bactericidal effect of normal human serum on E. coli strains from normals and from patients with urinary tract infections

Author

Jan Holmgren, S. Olling, K. Lincoln, U. Jodal, U. Lindberg, and L. Å. Hanson

Subjects
Microbiology (medical), Antigens, Bacterial, Blood Bactericidal Activity, business.industry, Urinary system, Immune Sera, General Medicine, Urine, Microbial Sensitivity Tests, Bactericidal effect, Microbiology, Infectious Diseases, Antigen, Normal children, Urinary Tract Infections, Escherichia coli, Medicine, Humans, business, Child, Feces, Escherichia coli Infections
Abstract

E. coli strains originating from faeces of normal children or from urine of children with urinary tract infections were analysed with regard to sensitivity to the bactericidal activity of normal human serum.

Published
1973

168. Asymptomatic bacteriuria--a serious disease?

Author

Ulf Jodal, L A Hanson, U. Lindberg, K. Lincoln, and Jan Holmgren

Subjects
medicine.medical_specialty, Bacteriuria, business.industry, General Engineering, General Medicine, Disease, medicine.disease, Bioinformatics, Internal medicine, Escherichia coli, General Earth and Planetary Sciences, Medicine, Humans, Kidney Diseases, business, Child, Asymptomatic bacteriuria, General Environmental Science, Research Article
Published
1972

169. Treatment trials in urinary tract infection (UTI) with special reference to the effect of antimicrobials on the fecal and periurethral flora

Author

J, Winberg, T, Bergström, K, Lincoln, and G, Lidin-Janson

Subjects
Male, Sulfonamides, Adolescent, Administration, Oral, Drug Resistance, Microbial, Anti-Bacterial Agents, Hospitalization, Feces, Nitrofurantoin, Urethra, Recurrence, Child, Preschool, Klebsiella, Pseudomonas, Urinary Tract Infections, Escherichia coli, Humans, Female, Alcaligenes, Child
Published
1973

170. STUDIES OF URINARY TRACT INFECTIONS IN INFANCY AND CHILDHOOD. IV. RELATION OF THE COLI ANTIBODY TITRE TO CLINICAL PICTURE AND TO SEROLOGICAL TYPE OF THE INFECTING ESCHERICHIA COLI IN ACUTE, UNCOMPLICATED URINARY TRACT INFECTIONS

Author

F. Ørskov, I. Ørskov, Lars Å. Hanson, Hans Jörgen Andersen, K. Lincoln, and Jan Winberg

Subjects
Hemagglutination, Fever, Urinary system, Blood Sedimentation, medicine.disease_cause, Microbiology, Serology, Allergy and Immunology, Cystitis, medicine, Escherichia coli, Humans, Child, Escherichia coli Infections, biology, Pyelonephritis, business.industry, Infant, General Medicine, Virology, Titer, Pediatrics, Perinatology and Child Health, Antibody Formation, Urinary Tract Infections, biology.protein, Antibody, business, Antibody formation
Published
1965

173. Studies of urinary tract infections in infancy and childhood. XII. Eighty consecutive patients with neonatal infection

Author

T, Bergström, H, Larson, K, Lincoln, and J, Winberg

Subjects
Male, Vesico-Ureteral Reflux, Sulfonamides, Bacteriuria, Anti-Infective Agents, Urinary, Infant, Newborn, Urography, Urine, Prognosis, Infant, Newborn, Diseases, Urinary Bladder Neck Obstruction, Leukocyte Count, Sex Factors, Recurrence, Urinary Tract Infections, Escherichia coli, Humans, Female, Cerebrospinal Fluid
Published
1972

174. Round table conference on non-obstructive urinary tract infections in children

Author

F. o̊SKOV, T. Bergström, K. Lincoln, Hans Jörgen Andersen, Lars Å. Hanson, I. o̊SKOV, and A. Nyegaard

Subjects
Male, Pediatrics, medicine.medical_specialty, Sulfonamides, Adolescent, business.industry, Urinary system, Infant, Drug Resistance, Microbial, General Medicine, Feces, Round table, Child, Preschool, Pediatrics, Perinatology and Child Health, Urinary Tract Infections, Escherichia coli, Medicine, Humans, Female, business, Child, Escherichia coli Infections
Published
1967

181. The indigenous nurse as crisis counselor a intervener

Author

E K Lincoln, J. L. Finan, C. D. Marshall, and H. H. Huessy

Subjects
business.industry, Mental Disorders, Nurses, General Medicine, Indigenous, Community Mental Health Services, Crisis Intervention, Education, Nursing, Continuing, Nursing, Workforce, Medicine, Humans, Curriculum, business, Vermont, Research Article
Published
1969

182. Resistant Urinary Infections Resulting from Changes in Resistance Pattern of Faecal Flora Induced by Sulphonamide and Hospital Environment*

Author

G Lidin-Janson, Jan Winberg, and K. Lincoln

Subjects
Male, Flora, medicine.drug_class, Sulfafurazole, Antibiotics, Drug resistance, Biology, Urine, medicine.disease_cause, Microbiology, Feces, Antibiotic resistance, medicine, Escherichia coli, Humans, Serotyping, General Environmental Science, Sulfonamides, General Engineering, Infant, Drug Resistance, Microbial, General Medicine, Papers and Originals, Hospitals, Multiple drug resistance, Urinary Tract Infections, General Earth and Planetary Sciences, Female, medicine.drug
Abstract

The faecal flora was studied in eight children admitted to hospital for treatment of a first urinary infection with sulphonamides. The original, sulphonamide-sensitive Escherichia coli organisms were found to disappear, to be replaced by other E. coli serotypes that were almost invariably resistant to sulphonamides. Some of these serotypes carried R-factors for multiple antibiotic resistance. Possibly some urinary infections with antibiotic-resistant organisms may be due to faecal organisms whose resistance has been changed by previous antibiotic treatment. Hence it is important to study the effects of individual antibiotics on the faecal flora.

Published
1970

183. An agent based framework for adaptive control and decision making of autonomous vehicles

Author

Alexei Lisitsa, Louise A. Dennis, Nicholas K. Lincoln, Michael Fisher, and Sandor M. Veres

Subjects
Engineering, Adaptive control, Computational complexity theory, business.industry, Distributed computing, General Medicine, Rational agent, Automation, Space exploration, Feature (machine learning), Robot, Hybrid automaton, Artificial intelligence, business
Abstract

The paper addresses the problem of defining a theoretical physical agent framework that combines rational agent decision making with abstractions from predictions and planning of the future of the physical environment. The objective of the new framework is to reduce complexity of logical inference of agents controlling autonomous vehicles and robots in space exploration, deep underwater exploration, defense reconnaissance, automated manufacturing and household automation. An essential feature of the framework is automated realtime evaluations of abstractions on the effects of future actions. Comparison is made with hybrid automaton based solutions in terms of computational complexity.

184. An Exploration of the Help-Seeking Behaviors of Arab-Muslims in the US: A Socio-ecological Approach

Author

Dalal Alhomaizi, Dalal Alhomaizi, Sarah Alsaidi, Ali Moalie, Nawal Muradwij, Christina P. C. Borba, Alisa K. Lincoln, Dalal Alhomaizi, Dalal Alhomaizi, Sarah Alsaidi, Ali Moalie, Nawal Muradwij, Christina P. C. Borba, and Alisa K. Lincoln

Abstract

Journal of Muslim Mental Health: vol. 12, no. 1, (dlps) 10381607.0012.102, http://hdl.handle.net/2027/spo.10381607.0012.102, This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. Please contact mpub-help@umich.edu to use this work in a way not covered by the license.

185. An Exploration of the Help-Seeking Behaviors of Arab-Muslims Living in the US: A Socioecological Model

Author

Dalal Alhomaizi, Dalal Alhomaizi, Sarah Alsaidi, Ali Moalie, Nawal Muradwij, Christina P. C. Borba, Alisa K. Lincoln, Dalal Alhomaizi, Dalal Alhomaizi, Sarah Alsaidi, Ali Moalie, Nawal Muradwij, Christina P. C. Borba, and Alisa K. Lincoln

Abstract

Journal of Muslim Mental Health: vol. 11, no. 1, (dlps) 10381607.0011.105, http://hdl.handle.net/2027/spo.10381607.0011.105, This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License. Please contact mpub-help@umich.edu to use this work in a way not covered by the license.

186. Bacterial Attachment and Inflammation in the Urinary Tract

Author

K. Lincoln, Ulf Jodal, Peter de Man, and Catharina Svanborg Edén

Subjects
Male, Bacteriuria, Urology, Urinary system, Virulence, Inflammation, Biology, medicine.disease_cause, Bacterial Adhesion, Body Temperature, Leukocyte Count, Immune system, Recurrence, Escherichia coli, Immunology and Allergy, Humans, Medicine, Prospective Studies, Child, Escherichia coli Infections, Vesico-Ureteral Reflux, Kidney, Pyelonephritis, business.industry, C-reactive protein, Infant, medicine.disease, Infectious Diseases, medicine.anatomical_structure, C-Reactive Protein, Child, Preschool, Immunology, biology.protein, Female, Glycolipids, medicine.symptom, business
Abstract

The mechanism whereby attachment enhances Escherichia coli virulence in the urinary tract was studied by a detailed analysis of the host response to bacteriuria. Episodes of bacteriuria in 1473 children were followed prospectively from 1970 to 1984. To study the inflammatory response to the bacteriuric epidoses, we recorded body temperature, C-reactive protein, microsedimentation rate, urinary leukocyte count, and renal concentrating capacity. Bacterial isolates from each episode were identified and saved, and the adhesive capacity of 2669 E. coli strains was defined by their binding to galactose alpha 1----4galactose beta-containing receptors. Inflammatory response was significantly higher and renal concentrating capacity significantly lower during episodes caused by attaching strains. There was a linear relation between the number of indicators of inflammation and the proportion of galactose alpha 1----4galactose beta-binding strains present. Vesicoureteric reflux potentiated the inflammatory response. Attaching strains of E. coli thus appeared to be more capable of causing inflammation than were other bacteria. The potentiating effect of attachment on inflammation explains the over-representation of galactose alpha 1----4galactose beta-recognizing bacteria in patients with acute pyelonephritis.

Published
1989
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187. Asymptomatic Bacteriuria in Pregnancy and its Relation to Premature Birth

Author

I. Jansson, K. Lincoln, and J. Winberg

Subjects
medicine.medical_specialty, Pediatrics, Bacteriuria, Labor Complication, Obstetric Labor, Premature, Pregnancy, medicine, Humans, Pregnancy Complications, Infectious, Asymptomatic bacteriuria, business.industry, Obstetrics, Premature labor, Obstetrics and Gynecology, General Medicine, medicine.disease, Obstetric Labor Complications, Obstetric labor complication, Pregnancy Complications, Premature birth, Urinary Tract Infections, Premature Birth, Female, business
Published
1964
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188. UTI DURING THE FIRST YEAR OF LIFE IN A GöTEBORG AREA 1977–79. I: BACTERIA FOUND AT SCREENING

Author

B. Wettergren, U Jodal, K Lincoln, Bo Jacobsson, and Anders Fasth

Subjects
education.field_of_study, Pediatrics, medicine.medical_specialty, business.industry, media_common.quotation_subject, Population, Reflux, First year of life, Bacteriuria, urologic and male genital diseases, medicine.disease, Asymptomatic, Pediatrics, Perinatology and Child Health, medicine, Girl, medicine.symptom, education, business, Asymptomatic bacteriuria, media_common, Clearance
Abstract

Purpose: To study bacteriuria in a defined population with special emphasis on asymptomatic infections. Methods: All newborn infants in the area were offered screening at 2 weeks, 3 and 10 months of age. Bacteriuria was confirmed by bladder puncture. Radiology and tests for level diagnosis were performed. Bacteria were analysed for virulence factors. No treatment was given if the child was asymptomatic and no signs of renal involvement were found. Results: From Oct 1977 to Dec 1979 2746 2-weeks old infants entered the study (96% participation). So far 2173 have been screened also at 3 months and 1269 at 10 months of age. Bacteriuria was confirmed in 31 boys (2.7%) and 8 girls (0.7%), in all cases without symptoms. Among the boys none had signs of renal involvement, 2 had reflux without dilatation. So far all have spontaneously cleared the bacteriuria before one year of age without any recurrences. One girl had scarred kidneys on IVP and was treated. The other girls became spontaneously free from bacteria within 6 months of diagnosis. 2 had asymptomatic recurrences. Conclusion: Asymptomatic bacteriuria during infancy was mostly transient. Renal involvement was rare. Screening for bacteriuria among healthy infants does not seem motivated.

Published
1980
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191. Cultivation potential projections of breadfruit (Artocarpus altilis) under climate change scenarios using an empirically validated suitability model calibrated in Hawai'i.

Author

Kalisi Mausio, Tomoaki Miura, and Noa K Lincoln

Subjects
Medicine, Science
Abstract

Humanity faces significant challenges to agriculture and human nutrition, and changes in climate are predicted to make such challenges greater in the future. Neglected and underutilized crops may play a role in mitigating and addressing such challenges. Breadfruit is a long-lived tree crop that is a nutritious, carbohydrate-rich staple, which is a priority crop in this regard. A fuzzy-set modeling approach was applied, refined, and validated for breadfruit to determine its current and future potential productivity. Hawai'i was used as a model system, with over 1,200 naturalized trees utilized to calibrate a habitat suitability model and 56 producer sites used to validate the model. The parameters were then applied globally on 17 global climate models at the RCP 4.5 and RCP 8.5 global climate projections for 2070. Overall, breadfruit suitability increases in area and in quality, with larger increases occurring in the RCP 8.5 projection. Current producing regions largely remain unchanged in both projections, indicating relative stability of production potential in current growing regions. Breadfruit, and other tropical indigenous food crops present strong opportunities for cultivation and food security risk management strategies moving forward.

Published
2020
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192. Global data on earthworm abundance, biomass, diversity and corresponding environmental properties

Author

Phillips, Helen R. P., Bach, Elizabeth M., Bartz, Marie L. C., Bennett, Joanne M., Beugnon, Rémy, Briones, Maria J. I., Brown, George G., Ferlian, Olga, Gongalsky, Konstantin B., Guerra, Carlos A., König-Ries, Birgitta, Krebs, Julia J., Orgiazzi, Alberto, Ramirez, Kelly S., Russell, David J., Schwarz, Benjamin, Wall, Diana H., Brose, Ulrich, Decaëns, Thibaud, Lavelle, Patrick, Loreau, Michel, Mathieu, Jérôme, Mulder, Christian, van der Putten, Wim H., Rillig, Matthias C., Thakur, Madhav P., de Vries, Franciska T., Wardle, David A., Ammer, Christian, Ammer, Sabine, Arai, Miwa, Ayuke, Fredrick O., Baker, Geoff H., Baretta, Dilmar, Barkusky, Dietmar, Beauséjour, Robin, Bedano, Jose C., Birkhofer, Klaus, Blanchart, Eric, Blossey, Bernd, Bolger, Thomas, Bradley, Robert L., Brossard, Michel, Burtis, James C., Capowiez, Yvan, Cavagnaro, Timothy R., Choi, Amy, Clause, Julia, Cluzeau, Daniel, Coors, Anja, Crotty, Felicity V., Crumsey, Jasmine M., Dávalos, Andrea, Cosín, Darío J. Díaz, Dobson, Annise M., Domínguez, Anahí, Duhour, Andrés Esteban, van Eekeren, Nick, Emmerling, Christoph, Falco, Liliana B., Fernández, Rosa, Fonte, Steven J., Fragoso, Carlos, Franco, André L. C., Fusilero, Abegail, Geraskina, Anna P., Gholami, Shaieste, González, Grizelle, Gundale, Michael J., López, Mónica Gutiérrez, Hackenberger, Branimir K., Hackenberger, Davorka K., Hernández, Luis M., Hirth, Jeff R., Hishi, Takuo, Holdsworth, Andrew R., Holmstrup, Martin, Hopfensperger, Kristine N., Lwanga, Esperanza Huerta, Huhta, Veikko, Hurisso, Tunsisa T., Iannone III, Basil V., Iordache, Madalina, Irmler, Ulrich, Ivask, Mari, Jesús, Juan B., Johnson-Maynard, Jodi L., Joschko, Monika, Kaneko, Nobuhiro, Kanianska, Radoslava, Keith, Aidan M., Kernecker, Maria L., Koné, Armand W., Kooch, Yahya, Kukkonen, Sanna T., Lalthanzara, H., Lammel, Daniel R., Lebedev, Iurii M., Le Cadre, Edith, Lincoln, Noa K., López-Hernández, Danilo, Loss, Scott R., Marichal, Raphael, Matula, Radim, Minamiya, Yukio, Moos, Jan Hendrik, Moreno, Gerardo, Morón-Ríos, Alejandro, Motohiro, Hasegawa, Muys, Bart, Neirynck, Johan, Norgrove, Lindsey, Novo, Marta, Nuutinen, Visa, Nuzzo, Victoria, Mujeeb Rahman, P., Pansu, Johan, Paudel, Shishir, Pérès, Guénola, Pérez-Camacho, Lorenzo, Ponge, Jean-François, Prietzel, Jörg, Rapoport, Irina B., Rashid, Muhammad Imtiaz, Rebollo, Salvador, Rodríguez, Miguel Á., Roth, Alexander M., Rousseau, Guillaume X., Rozen, Anna, Sayad, Ehsan, van Schaik, Loes, Scharenbroch, Bryant, Schirrmann, Michael, Schmidt, Olaf, Schröder, Boris, Seeber, Julia, Shashkov, Maxim P., Singh, Jaswinder, Smith, Sandy M., Steinwandter, Michael, Szlavecz, Katalin, Talavera, José Antonio, Trigo, Dolores, Tsukamoto, Jiro, Uribe-López, Sheila, de Valença, Anne W., Virto, Iñigo, Wackett, Adrian A., Warren, Matthew W., Webster, Emily R., Wehr, Nathaniel H., Whalen, Joann K., Wironen, Michael B., Wolters, Volkmar, Wu, Pengfei, Zenkova, Irina V., Zhang, Weixin, Cameron, Erin K., Eisenhauer, Nico, German Centre for Integrative Biodiversity Research (iDiv), Leipzig University, Saint Mary's University [Halifax], Colorado State University [Fort Collins] (CSU), University of Coimbra [Portugal] (UC), Martin-Luther-University Halle-Wittenberg, University of Canberra, Universidade de Vigo, Embrapa Forestry, Brazilian Agricultural Research Corporation (Embrapa), A.N. Severtsov Institute of Ecology and Evolution, Russian Academy of Sciences [Moscow] (RAS), Lomonosov Moscow State University (MSU), Friedrich-Schiller-Universität = Friedrich Schiller University Jena [Jena, Germany], European Commission - Joint Research Centre [Ispra] (JRC), Netherlands Institute of Ecology (NIOO-KNAW), University of Freiburg [Freiburg], Department of Biometry and Environmental System Analysis, Albert-Ludwigs-Universität Freiburg, Centre d’Ecologie Fonctionnelle et Evolutive (CEFE), Université Paul-Valéry - Montpellier 3 (UPVM)-École pratique des hautes études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud])-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Institut Agro - Montpellier SupAgro, Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro), Institut d'écologie et des sciences de l'environnement de Paris (iEES Paris ), Institut de Recherche pour le Développement (IRD)-Sorbonne Université (SU)-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Station d'Ecologie Théorique et Expérimentale (SETE), Centre National de la Recherche Scientifique (CNRS)-Fédération de Recherche Agrobiosciences, Interactions et Biodiversité (FR AIB), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS), University of Catania [Italy], Wageningen University and Research [Wageningen] (WUR), Freie Universität Berlin, Institute for Biodiversity and Ecosystem Dynamics (IBED), University of Amsterdam [Amsterdam] (UvA), Asian School of the Environment (ASE), Nanyang Technological University [Singapour], Georg-August-University = Georg-August-Universität Göttingen, National Agriculture and Food Research Organization (NARO), University of Nairobi (UoN), Commonwealth Scientific and Industrial Research Organisation [Canberra] (CSIRO), Santa Catarina State University (UDESC), Leibniz-Zentrum für Agrarlandschaftsforschung = Leibniz Centre for Agricultural Landscape Research (ZALF), Université de Sherbrooke (UdeS), National University of Río Cuarto = Universidad Nacional de Río Cuarto (UNRC), Brandenburg University of Technology [Cottbus – Senftenberg] (BTU), Ecologie fonctionnelle et biogéochimie des sols et des agro-écosystèmes (UMR Eco&Sols), Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Institut de Recherche pour le Développement (IRD)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Institut Agro - Montpellier SupAgro, Cornell University [New York], University College Dublin [Dublin] (UCD), Environnement Méditerranéen et Modélisation des Agro-Hydrosystèmes (EMMAH), Avignon Université (AU)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), University of Adelaide, University of Toronto, Ecologie et biologie des interactions (EBI), Université de Poitiers-Centre National de la Recherche Scientifique (CNRS), Ecosystèmes, biodiversité, évolution [Rennes] (ECOBIO), Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Institut Ecologie et Environnement (INEE), Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS)-Observatoire des Sciences de l'Univers de Rennes (OSUR), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Institut national des sciences de l'Univers (INSU - CNRS)-Université de Rennes 2 (UR2), Université de Rennes (UNIV-RENNES)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Institut national des sciences de l'Univers (INSU - CNRS)-Université de Rennes 2 (UR2), Université de Rennes (UNIV-RENNES)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Centre National de la Recherche Scientifique (CNRS), ECT Oekotoxikologie GmbH, Institute of Biological, Environmental and Rural Sciences (IBERS), Biotechnology and Biological Sciences Research Council (BBSRC)-Aberystwyth University, Royal Agricultural University (RAU), University of Georgia [USA], State University of New York (SUNY), Department of Biodiversity, Ecology and Evolution [Madrid], Universidad Complutense de Madrid = Complutense University of Madrid [Madrid] (UCM), Yale University [New Haven], Universidad Nacional de Luján [Buenos Aires], Louis Bolk Institute (LBI), Trier University, Animal Biodiversity and Evolution, Institute of Evolutionary Biology (IBE), Department of Soil and Crop Sciences [Fort Collins], Biodiversity and Systematic Network, Instituto de Ecología A.C., Department of Biology [Fort Collins], Department of Biological Science and Environmental Studies, University of the Philippines - Mindanao, Faculty of Bioscience Engineering - Laboratory of Environmental Toxicology and Aquatic Ecology, Universiteit Gent = Ghent University [Belgium] (UGENT), Center for Forest Ecology and Productivity (RAS), Razi University of Kermanshah, USDA Forest Service, Department of Forest Ecology and Management, Swedish University of Agricultural Sciences (SLU), Josip Juraj Strossmayer University of Osijek, Agriculture engineering, Agroecology Postgraduate Program, Maranhão State University, Agriculture Victoria (AgriBio), Kyushu University [Fukuoka], Minnesota Pollution Control Agency, Department of Bioscience [Aarhus], Northern Kentucky University, Departamento de Agricultura, Sociedad y Ambiente, EI Colegio de la Frontera Sur (ECOSUR), Consejo Nacional de Ciencia y Tecnología [Mexico] (CONACYT)-Consejo Nacional de Ciencia y Tecnología [Mexico] (CONACYT), Soil Physics and Land Management Group, University of Jyväskylä (JYU), College of Agriculture, Environmental and Human Sciences, Lincoln University of Missouri, School of Forest Resources and Conservation [Gainesville] (UF|IFAS|FFGS), Institute of Food and Agricultural Sciences [Gainesville] (UF|IFAS), University of Florida [Gainesville] (UF)-University of Florida [Gainesville] (UF), Banat University of Agricultural Sciences and Veterinary Medicine (USAMVBT), Christian-Albrechts University of Kiel, Tallinn University of Technology (TTÜ), University of Idaho [Moscow, USA], Faculty of Food and Agricultural Sciences, Fukushima University, Matej Bel University (UMB), UK Centre for Ecology & Hydrology, Natural Environment Research Council (NERC), Université Nangui Abrogoua (UNA), Faculty of Natural Resources and Marine Sciences [Tarbiat], Tarbiat Modares University [Tehran], Natural Resources Institute Finland (LUKE), Department of Zoology, Pachhunga University College, Skolkovo Institute of Science and Technology [Moscow] (Skoltech), Sol Agro et hydrosystème Spatialisation (SAS), Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-INSTITUT AGRO Agrocampus Ouest, University of Hawai'i [Honolulu] (UH), Universidad Central de Venezuela (UCV), Instituto de Zoología y Ecología Tropical (IZET), Oklahoma State University [Stillwater] (OSU), Agrosystèmes Biodiversifiés (UMR ABSys), Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Centre International de Hautes Etudes Agronomiques Méditerranéennes - Institut Agronomique Méditerranéen de Montpellier (CIHEAM-IAMM), Centre International de Hautes Études Agronomiques Méditerranéennes (CIHEAM)-Centre International de Hautes Études Agronomiques Méditerranéennes (CIHEAM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Institut Agro - Montpellier SupAgro, Département Performances des systèmes de production et de transformation tropicaux (Cirad-PERSYST), Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad), Czech University of Life Sciences Prague (CZU), Tochigi Prefectural Museum, Thuenen-Institute of Biodiversity, Thuenen-Institute of Organic Farming, University of Extremadura, INDEHESA, Forestry School, Conservación de la Biodiversidad, El Colegio de la Frontera Sur, Doshisha University [Kyoto], Department of Earth and Environmental Sciences [Leuven-Heverlee], Catholic University of Leuven - Katholieke Universiteit Leuven (KU Leuven), Research Institute for Nature and Forest (INBO), School of Agricultural, Forest and Food Sciences, Bern University of Applied Sciences (BFH), Natural Area Consultants, Department of Zoology, PSMO College, CSIRO Marine and Atmospheric Research (CSIRO-MAR), Adaptation et diversité en milieu marin (AD2M), Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS)-Station biologique de Roscoff (SBR), Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Phipps Conservatory and Botanical Gardens (PHIPPS), Universidad de Alcalá - University of Alcalá (UAH), Forest Ecology and Restoration Group, Department of Life Sciences, Mécanismes Adaptatifs et Evolution (MECADEV), Muséum national d'Histoire naturelle (MNHN)-Centre National de la Recherche Scientifique (CNRS), Technische Universität Munchen - Université Technique de Munich [Munich, Allemagne] (TUM), Department of Ecology and Ecosystem Management, Geobotany, Tembotov Institute of Ecology of Mountain Territories, Russian Academy of Sciences, King Abdulaziz University, Center of Excellence in Environmental Studies, Global Change Ecology and Evolution Research Groupp (GloCEE), Department of Life Sciences, University of Alcalá, University of Minnesota [Twin Cities] (UMN), University of Minnesota System, Postgraduate Program in Biodiversity and Conservation, Federal University of Maranhão, Uniwersytet Jagielloński w Krakowie = Jagiellonian University (UJ), College of Natural Resources, University of Wisconsin, The Morton Arboretum, Department Engineering for Crop Production, Leibniz Institute for Agricultural Engineering and Bioeconomy (ATB), School of Agriculture and Food Science, UCD School of Geography, UCD Earth Institute, University College, Technische Universität Braunschweig = Technical University of Braunschweig [Braunschweig], Institute of Geoecology, Leopold Franzens Universität Innsbruck - University of Innsbruck, European Academy Bozen/Bolzano (EURAC), Institute for Alpine Environment, European Academy of Bozen-Bolzano (EURAC), Institute of Physicochemical and Biological Problems in Soil Science, RAS, Institute of Mathematical Problems in Biology (IMPB RAS), Post Graduate Department of Zoology, Khalsa College Amritsar, Morton K. Blaustein Department of Earth and Planetary Sciences [Baltimore], Johns Hopkins University (JHU), Universidad de La Laguna [Tenerife - SP] (ULL), Kochi University, Juárez Autonomous University of Tabasco, Nanotechnology Engineering, Multidisciplinary Academic Division of Jalpa de Méndez, Food & Agriculture, WWF-Netherlands, Universidad Pública de Navarra [Espagne] = Public University of Navarra (UPNA), Department of Soil, Water and Climate, University of Minnesota System-University of Minnesota System, Earth Innovation Institute, University of California [Davis] (UC Davis), University of California (UC), Department of Natural Resources and Environmental Management, University of Hawaii, McGill University = Université McGill [Montréal, Canada], Natural resource sciences, The Nature Conservancy, Justus-Liebig-Universität Gießen = Justus Liebig University (JLU), Southwest Minzu University [Chengdu], Institute of Industrial Ecology Problems of the North of the Kola Science Center of RAS, Henan Agricultural University, Faculty of Biological and Environmental Sciences [Helsinki], Helsingin yliopisto = Helsingfors universitet = University of Helsinki, H.R.P.P., B.K-R., and the sWorm workshops were supported by the sDiv [Synthesis Centre of the German Centre for Integrative Biodiversity Research (iDiv) Halle-Jena-Leipzig (DFG FZT 118)]. H.R.P.P., O.F. and N.E. acknowledge funding by the European Research Council (ERC) under the European Union's Horizon 2020 research and innovation programme (grant agreement no. 677232 to NE). K.S.R. and W.H.v.d.P. were supported by ERC-ADV grant 323020 to W.H.v.d.P. Also supported by iDiv (DFG FZT118) Flexpool proposal 34600850 (C.A.G. and N.E.), the Academy of Finland (285882) and the Natural Sciences and Engineering Research Council of Canada (postdoctoral fellowship and RGPIN-2019-05758) (E.K.C.), German Federal Ministry of Education and Research (01LO0901A) (D.J.R.), ERC-AdG 694368 (M.R.), the TULIP Laboratory of Excellence (ANR-10-LABX-41) (M.L), and the BBSRC David Phillips Fellowship to F.T.d.V. (BB/L02456X/1). In addition, data collection was funded by the Russian Foundation for Basic Research (12-04-01538-a, 12-04-01734-a, 14-44-03666-r_center_a, 15-29-02724-ofi_m, 16-04-01878-a 19-05-00245, 19-04-00-609-a), Tarbiat Modares University, Aurora Organic Dairy, UGC(NERO) (F. 1-6/Acctt./NERO/2007-08/1485), Natural Sciences and Engineering Research Council (RGPIN-2017-05391), Slovak Research and Development Agency (APVV-0098-12), Science for Global Development through Wageningen University, Norman Borlaug LEAP Programme and International Atomic Energy Agency (IAEA), Sao Paulo Research Foundation - FAPESP (12/22510-8), Oklahoma Agricultural Experiment Station, INIA - Spanish Agency (SUM 2006-00012-00-0), Royal Canadian Geographical Society, Environmental Protection Agency (Ireland) (2005-S-LS-8), University of Hawai'i at Manoa (HAW01127H, HAW01123M), European Union FP7 (FunDivEurope, 265171, ROUTES 265156), U.S. Department of the Navy, Commander Pacific Fleet (W9126G-13-2-0047), Science and Engineering Research Board (SB/SO/AS-030/2013) Department of Science and Technology, New Delhi, India, Strategic Environmental Research and Development Program (SERDP) of the U.S. Department of Defense (RC-1542), Maranhao State Research Foundation (FAPEMA 03135/13, 02471/17), Coordination for the Improvement of Higher Education Personnel (CAPES 3281/2013), Ministry of Education, Youth and Sports of the Czech Republic (LTT17033), Colorado Wheat Research Foundation, Zone Atelier Alpes, French National Research Agency (ANR-11-BSV7-0020, ANR-09-STRA-0002, ANR 06 BIODIV 0009), Austrian Science Fund (P16027, T441), Landwirtschaftliche Rentenbank Frankfurt am Main, Welsh Government and the European Agricultural Fund for Rural Development (Project Ref. A AAB 62 03 qA731606), SEPAQ, Ministry of Agriculture and Forestry of Finland, Science Foundation Ireland (EEB0061), University of Toronto (Faculty of Forestry), National Science and Engineering Research Council of Canada, Haliburton Forest & Wildlife Reserve, NKU College of Arts & Sciences Grant, osterreichische Forschungsforderungsgesellschaft (837393 and 837426), Mountain Agriculture Research Unit of the University of Innsbruck, Higher Education Commission of Pakistan, Kerala Forest Research Institute, Peechi, Kerala, UNEP/GEF/TSBF-CIAT Project on Conservation and Sustainable Management of Belowground Biodiversity, Ministry of Agriculture and Forestry of Finland, Complutense University of Madrid/European Union FP7 project BioBio (FPU UCM 613520), GRDC, AWI, LWRRDC, DRDC, CONICET (National Scientific and Technical Research Council) and FONCyT (National Agency of Scientific and Technological Promotion) (PICT, PAE, PIP), Universidad Nacional de Lujan y FONCyT (PICT 2293 (2006)), Fonds de recherche sur la nature et les technologies du Quebec (131894), Deutsche Forschungsgemeinschaft (SCHR1000/3-1, SCHR1000/6-1, 6-2 (FOR 1598), WO 670/7-1, WO 670/7-2, & SCHA 1719/1-2), CONACYT (FONDOS MIXTOS TABASCO/PROYECTO11316), NSF (DGE-0549245, DGE-0549245, DEB-BE-0909452, NSF1241932, LTER Program DEB-97-14835), Institute for Environmental Science and Policy at the University of Illinois at Chicago, Dean's Scholar Program at UIC, Garden Club of America Zone VI Fellowship in Urban Forestry from the Casey Tree Endowment Fund, J.E. Weaver Competitive Grant from the Nebraska Chapter of The Nature Conservancy, The College of Liberal Arts and Sciences at Depaul University, Elmore Hadley Award for Research in Ecology and Evolution from the UIC Dept. of Biological Sciences, Spanish CICYT (AMB96-1161, REN2000-0783/GLO, REN2003-05553/GLO, REN2003-03989/GLO, CGL2007-60661/BOS), Yokohama National University, MEXT KAKENHI (25220104), Japan Society for the Promotion of Science KAKENHI (25281053, 17KT0074, 25252026), ADEME (0775C0035), Ministry of Science, Innovation and Universities of Spain (CGL2017-86926-P), Syngenta Philippines, UPSTREAM, LTSER (Val Mazia/Matschertal), Marie Sklodowska Curie Postdoctoral Fellowship (747607), National Science & Technology Base Resource Survey Project of China (2018FY100306), McKnight Foundation (14-168), Program of Fundamental Researches of Presidium of Russian Academy of Sciences (AAAA-A18-118021490070-5), Brazilian National Council for Scientific and Technological Development (CNPq 310690/2017-0, 404191/2019-3, 307486/2013-3), French Ministry of Foreign and European Affairs, Bavarian Ministry for Food, Agriculture and Forestry (Project No B62), INRA AIDY project, MIUR PRIN 2008, Idaho Agricultural Experiment Station, Estonian Science Foundation, Ontario Ministry of the Environment, Canada, Russian Science Foundation (16-17-10284), National Natural Science Foundation of China (41371270), Australian Research Council (FT120100463), USDA Forest Service-IITF. Open Access funding enabled and organized by Projekt DEAL., ANR-10-LABX-0041,TULIP,Towards a Unified theory of biotic Interactions: the roLe of environmental(2010), ANR-11-BSV7-0020,METABAR,Metacode-barre ADN pour une nouvelle génération de suivi de la biodiversité(2011), ANR-09-STRA-0002,FORGECO,Du diagnostic à l'action: créer les conditions d'une gestion integrée et viable des écosystèmes forestiers sur les territoires(2009), ANR-06-BDIV-0009,AMAZ_BD,Biodiversité des paysages amazoniens. Déterminants socio-économiques et productio de biens et services écosystèmiques(2006), European Project: 677232,H2020,ERC-2015-STG,ECOWORM(2016), European Project: 323020,EC:FP7:ERC,ERC-2012-ADG_20120314,SPECIALS(2013), European Project: 265171,EC:FP7:ENV,FP7-ENV-2010,FUNDIVEUROPE(2010), European Project: 265156,EC:FP7:ENV,FP7-ENV-2010,ROUTES(2011), European Project: ERC-2015-AdG 694368, European Project: 227161,EC:FP7:KBBE,FP7-KBBE-2008-2B,BIOBIO(2009), Terrestrial Ecology (TE), Université Paul-Valéry - Montpellier 3 (UPVM)-École Pratique des Hautes Études (EPHE), Université de Toulouse (UT)-Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS), Department of Natural Resources & The Environment [CALS], College of Agriculture and Life Sciences [Cornell University] (CALS), Cornell University [New York]-Cornell University [New York], Department of Entomology [CALS], Université de Rennes (UR)-Institut Ecologie et Environnement (INEE), Université de Rennes (UR)-Institut national des sciences de l'Univers (INSU - CNRS)-Université de Rennes 2 (UR2)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Institut national des sciences de l'Univers (INSU - CNRS)-Université de Rennes 2 (UR2)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Centre National de la Recherche Scientifique (CNRS), Universiteit Gent = Ghent University (UGENT), Kyushu University, Universidad de Extremadura - University of Extremadura (UEX), Adaptation et diversité en milieu marin (ADMM), Institut national des sciences de l'Univers (INSU - CNRS)-Station biologique de Roscoff (SBR), Faculty of Biological and Environmental Sciences, Organismal and Evolutionary Biology Research Programme, Universidad Pública de Navarra / Nafarroako Unibertsitate Publikoa. ISFOOD - Institute for Innovation and Sustainable Development in Food Chain, Universidad Pública de Navarra. Departamento de Ciencias, Nafarroako Unibertsitate Publikoa. Zientziak Saila, Global Soil Biodiversity Initiative and School of Global Environmental Sustainability, Colorado State University, Universidade Positivo, Senckenberg Museum for Natural History Görlitz, Department of Soil Zoology, Université Paul-Valéry - Montpellier 3 (UPVM)-Centre international d'études supérieures en sciences agronomiques (Montpellier SupAgro)-École pratique des hautes études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud])-Institut national d’études supérieures agronomiques de Montpellier (Montpellier SupAgro), Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Institut de Recherche pour le Développement (IRD)-Sorbonne Université (SU)-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Station d'écologie théorique et expérimentale (SETE), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Observatoire Midi-Pyrénées (OMP), Météo France-Centre National d'Études Spatiales [Toulouse] (CNES)-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Météo France-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD), University of Göttingen - Georg-August-Universität Göttingen, Centre of Biodiversity and Sustainable Land Use, Department of Silviculture and Forest Ecology of the Temperate Zones, Georg-August-University [Göttingen], Faculty of Forest Sciences and Forest Ecology, Institute for Agro-Environmental Sciences, Rwanda Institute for Conservation Agriculture (RICA), Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Institut de Recherche pour le Développement (IRD)-Centre international d'études supérieures en sciences agronomiques (Montpellier SupAgro)-Institut national d’études supérieures agronomiques de Montpellier (Montpellier SupAgro), UCD School of Biology & Environmental Science, UCD Earth Institute, University College Dublin, School of Agriculture, Food and Wine, Waite Research Institute, Faculty of Forestry, University of Toronto, Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS)-Observatoire des Sciences de l'Univers de Rennes (OSUR)-Centre National de la Recherche Scientifique (CNRS), Aberystwyth University, Odum School of Ecology, Department of Biological Sciences, SUNY Cortland, Yale School Forestry & Environment Studies, Ciencias Básicas, Instituto de Ecología y Desarrollo Sustentable -INEDES, Universidad Nacional de Lujan, Université Nangui Abrogoua, Tarbiat Modaras University, AGROCAMPUS OUEST, Oklahoma State University [Stillwater], Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Centre international d'études supérieures en sciences agronomiques (Montpellier SupAgro)-Centre International de Hautes Etudes Agronomiques Méditerranéennes - Institut Agronomique Méditerranéen de Montpellier (CIHEAM-IAMM), Centre International de Hautes Études Agronomiques Méditerranéennes (CIHEAM)-Centre International de Hautes Études Agronomiques Méditerranéennes (CIHEAM)-Institut national d’études supérieures agronomiques de Montpellier (Montpellier SupAgro), Station biologique de Roscoff (SBR), Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS), Department of Animal Biology (Zoology area), Science Faculty, University of La Laguna, University of California, Justus-Liebig-University [Gießen, Germany], University of Helsinki, HELEN R. P. PHILLIPS, German Centre for Integrative Biodiversity Research, ERIN K. CAMERON, Saint Mary’s University, NICO EISENHAUER, German Centre for Integrative Biodiversity Research, Leipzig University., Wageningen University, JOSÉ ANTONIO TALAVERA, University of La Laguna, DOLORES TRIGO, University Complutense of Madrid, JIRO TSUKAMOTO, Kochi University, SHEILA URIBE-LÓPEZ, Juárez Autonomous University of Tabasco, ANNE W. DE VALENÇA, Unit Food & Agriculture, WWF-Netherlands, IÑIGO VIRTO, Universidad Pública de Navarra, ADRIAN A. WACKETT, University of Minnesota, MATTHEW W. WARREN, Earth Innovation Institute, WEIXIN ZHANG, Henan University, DANIEL CLUZEAU, Université de Rennes, ANJA COORS, ECT Oekotoxikologie GmbH, FELICITY V. CROTTY, Aberystwyth Universtiy, Royal Agricultural University, JASMINE M. CRUMSEY, University of Georgia, Saint Marys University, ELIZABETH M. BACH, Colorado State University, MARIE L. C. BARTZ, Universidade Positivo, University of Coimbra, JOANNE M. BENNETT, German Centre for Integrative Biodiversity Research, Martin Luther University Halle-Wittenberg, RÉMY BEUGNON, German Centre for Integrative Biodiversity Research, MARIA J. I. BRIONES, Universidad de Vigo, GEORGE GARDNER BROWN, CNPF, OLGA FERLIAN, German Centre for Integrative Biodiversity Research, KONSTANTIN B. GONGALSKY, Russian Academy of Sciences, Lomonosov Moscow State University, CARLOS A. GUERRA, German Centre for Integrative Biodiversity Research, BIRGITTA KÖNIG-RIES, German Centre for Integrative Biodiversity Research, Friedrich Schiller University, JULIA J. KREBS, German Centre for Integrative Biodiversity Research, ALBERTO ORGIAZZI, European Commission, Joint Research Centre, KELLY S. RAMIREZ, Netherlands Institute of Ecology, DAVID J. RUSSELL, Senckenberg Museum for Natural History Görlitz, BENJAMIN SCHWARZ, University of Freiburg, DIANA H. WALL, Colorado State University, ULRICH BROSE, German Centre for Integrative Biodiversity Research, Friedrich Schiller University Jena, THIBAUD DECAËNS, Univ Paul Valéry Montpellier, PATRICK LAVELLE, Institut d’Ecologie et des Sciences de l’Environnement, MICHEL LOREAU, Theoretical and Experimental Ecology Station, JÉRÔME MATHIEU, Institute of Ecology and Environmental Sciences of Paris, Institut d’Ecologie et des Sciences de l’Environnement de Paris, CHRISTIAN MULDER, University of Catania, WIM H. VAN DER PUTTEN, Netherlands Institute of Ecology, MATTHIAS C. RILLIG, Freie Universität Berlin, MADHAV P. THAKUR, Netherlands Institute of Ecology, FRANCISKA T. DE VRIES, University of Amsterdam, DAVID A. WARDLE, Nanyang Technological University, CHRISTIAN AMMER, University of Göttingen, SABINE AMMER, University of Göttingen, MIWA ARAI, National Agriculture and Food Research Organization, FREDRICK O. AYUKE, University of Nairobi, Rwanda Institute for Conservation Agriculture, GEOFF H. BAKER, Health & Biosecurity, DILMAR BARETTA, Santa Catarina State University, DIETMAR BARKUSKY, Leibniz Centre for Agricultural Landscape Research, ROBIN BEAUSÉJOUR, Université de Sherbrooke, JOSE C. BEDANO, National University of Rio Cuarto, KLAUS BIRKHOFER, Brandenburg University of Technology, ERIC BLANCHART, Institut Agro, BERND BLOSSEY, Cornell University, THOMAS BOLGER, University College Dublin, ROBERT L. BRADLEY, Université de Sherbrooke, MICHEL BROSSARD, Institut Agro, JAMES C. BURTIS, Cornell University, YVAN CAPOWIEZ, Site Agroparc, TIMOTHY R. CAVAGNARO, The University of Adelaide, AMY CHOI, University of Toronto, JULIA CLAUSE, Université de Poitiers, ANDREA DÁVALOS, SUNY Cortland, DARÍO J. DÍAZ COSÍN, University Complutense of Madrid, ANNISE M. DOBSON, Yale University, ANAHÍ DOMÍNGUEZ, National University of Rio Cuarto, ANDRÉS ESTEBAN DUHOUR, Universidad Nacional de Luján, NICK VAN EEKEREN, Louis Bolk Institute, CHRISTOPH EMMERLING, University of Trier, LILIANA B. FALCO, Universidad Nacional de Luján, ROSA FERNÁNDEZ, Institute of Evolutionary Biology, STEVEN J. FONTE, Colorado State University, CARLOS FRAGOSO, Institute of Ecology A.C., ANDRÉ L. C. FRANCO, Colorado State University, ABEGAIL FUSILERO, University of the Philippines Mindanao, Ghent University, ANNA P. GERASKINA, Center for Forest Ecology and Productivity RAS, SHAIESTE GHOLAMI, Razi University, GRIZELLE GONZÁLEZ, International Institute of Tropical Forestry, MICHAEL J. GUNDALE, Swedish University of Agricultural Sciences, MÓNICA GUTIÉRREZ LÓPEZ, University Complutense of Madrid, BRANIMIR K. HACKENBERGER, University of Osijek, DAVORKA K. HACKENBERGER, University of Osijek, LUIS M. HERNÁNDEZ, Maranhão State University, JEFF R. HIRTH, Department of Jobs, Precincts and Regions, Agriculture Victoria, TAKUO HISHI, Kyushu University, ANDREW R. HOLDSWORTH, Minnesota Pollution Control Agency, MARTIN HOLMSTRUP, Aarhus University, KRISTINE N. HOPFENSPERGER, Northern Kentucky University, ESPERANZA HUERTA LWANGA, El Colegio de la Frontera Sur, Wageningen University & Research, VEIKKO HUHTA, University of Jyväskylä, TUNSISA T. HURISSO, Colorado State University, Lincoln University of Missouri, BASIL V. IANNONE III, University of Florida, MADALINA IORDACHE, University of Agricultural Sciences and Veterinary Medicine of Banat 'King Michael the 1st of Romania', ULRICH IRMLER, University of Kiel, MARI IVASK, Tallinn University of Technology, JUAN B. JESÚS, University Complutense of Madrid, JODI L. JOHNSON-MAYNARD, University of Idaho, MONIKA JOSCHKO, Leibniz Centre for Agricultural Landscape Research, NOBUHIRO KANEKO, Fukushima University, RADOSLAVA KANIANSKA, Matej Bel University, AIDAN M. KEITH, Leibniz Centre for Agricultural Landscape Research, MARIA L. KERNECKER, Leibniz Centre for Agricultural Landscape Research, ARMAND W. KONÉ, Université Nangui Abrogoua, YAHYA KOOCH, Tarbiat Modares University, SANNA T. KUKKONEN, Natural Resources Institute Finland, H. LALTHANZARA, Pachhunga University College, DANIEL R. LAMMEL, Freie Universität Berlin, IURII M. LEBEDEV, Russian Academy of Sciences, M.V. Lomonosov Moscow State University, Skolkovo Institute of Science and Technology, EDITH LE CADRE, Institut Agro, NOA K. LINCOLN, University of Hawai’i at Manoa, DANILO LÓPEZ-HERNÁNDEZ, Universidad Central de Venezuela, SCOTT R. LOSS, Oklahoma State University, RAPHAEL MARICHAL, Univ Montpellier, RADIM MATULA, Czech University of Life Sciences Prague, YUKIO MINAMIYA, Tochigi Prefectural Museum, JAN HENDRIK MOOS, Thuenen-Institute of Biodiversity, GERARDO MORENO, University of Extremadura, ALEJANDRO MORÓN-RÍOS, El Colegio de la Frontera Sur, HASEGAWA MOTOHIRO, Doshisha University, BART MUYS, Department of Earth & Environmental Sciences, Division of Forest, Nature and Landscape, JOHAN NEIRYNCK, Research Institute for Nature and Forest, LINDSEY NORGROVE, Bern University of Applied Sciences, MARTA NOVO, University Complutense of Madrid, VISA NUUTINEN, Natural Resources Institute Finland, VICTORIA NUZZO, Natural Area Consultants, P. MUJEEB RAHMAN, PSMO College, JOHAN PANSU, CSIRO Ocean and Atmosphere, Sorbonne Université, SHISHIR PAUDEL, Oklahoma State University, Phipps Conservatory and Botanical Gardens, GUÉNOLA PÉRÈS, CNRS-Université de Rennes, Institut Agro, LORENZO PÉREZ CAMACHO, University of Alcalá, JEAN-FRANÇOIS PONGE, Muséum National d’Histoire Naturelle, JÖRG PRIETZEL, Technical University of Munich, IRINA B. RAPOPORT, Russian Academy of Sciences, MUHAMMAD IMTIAZ RASHID, King Abdulaziz University, SALVADOR REBOLLO, University of Alcalá, MIGUEL Á. RODRÍGUEZ, University of Alcalá, ALEXANDER M. ROTH, University of Minnesot, Friends of the Mississippi River, GUILLAUME X. ROUSSEAU, Maranhão State University, Federal University of Maranhão, ANNA ROZEN, University of Wisconsin, EHSAN SAYAD, Razi University, LOES VAN SCHAIK, Wageningen University & Research, BRYANT SCHARENBROCH, University of Wisconsin, MICHAEL SCHIRRMANN, Leibniz Institute for Agricultural Engineering and Bioeconomy, OLAF SCHMIDT, University College Dublin, Agriculture and Food Science Centre, BORIS SCHRÖDER, Technische Universität Braunschweig, JULIA SEEBER, University of Innsbruck, MAXIM P. SHASHKOV, Russian Academy of Sciences, JASWINDER SINGH, Khalsa College Amritsar, SANDY M. SMITH, University of Toronto, MICHAEL STEINWANDTER, Institute for Alpine Environment, KATALIN SZLAVECZ, Johns Hopkins University, EMILY R. WEBSTER, University of California, NATHANIEL H. WEHR, University of Hawaii, JOANN K. WHALEN, Natural Resource Sciences, McGill University, MICHAEL B. WIRONEN, The Nature Conservancy, VOLKMAR WOLTERS, Animal Ecology, Justus Liebig University, PENGFEI WU, Southwest Minzu University, IRINA V. ZENKOVA, Institute of North Industrial Ecology Problems, Institut de Recherche pour le Développement (IRD)-Météo France-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Université Fédérale Toulouse Midi-Pyrénées-Institut de Recherche pour le Développement (IRD)-Météo France-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS), Centre National de la Recherche Scientifique (CNRS)-Observatoire des Sciences de l'Univers de Rennes (OSUR)-Institut Ecologie et Environnement (INEE), Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES), Centre National de la Recherche Scientifique (CNRS)-Station biologique de Roscoff (SBR), and Technical University of Munich (TUM)

Subjects
Data Descriptor, Distribuição Geográfica, Plan_S-Compliant-OA, Soil, Biomass, biodiversity, Diversity, Ecology, Biodiversidade, Biodiversity, eliöyhteisöt, maaperäeliöstö, PE&RC, Computer Science Applications, Multidisciplinary Sciences, Biogeography, international, 1181 Ecology, evolutionary biology, Ecosystem engineers, Science & Technology - Other Topics, Statistics, Probability and Uncertainty, Information Systems, Statistics and Probability, lierot, Science, Invertebrados, Library and Information Sciences, [SDV.SA.SDS]Life Sciences [q-bio]/Agricultural sciences/Soil study, Ecology and Environment, Education, eliömaantiede, [SDV.EE.ECO]Life Sciences [q-bio]/Ecology, environment/Ecosystems, Minhoca, Serviço ambiental, BIODIVERSITY CHANGE, Life Science, Ecosystem services, Earthworms, Datasets, Animals, Spatial distribution, Community ecology, Oligochaeta, Laboratorium voor Nematologie, Ecosystem, 1172 Environmental sciences, biogeography, Science & Technology, LAND-USE, Biology and Life Sciences, PLATFORM, Bodemfysica en Landbeheer, Ecología, Ecossistema, biodiversiteetti, Soil Physics and Land Management, Solo, Biologia do Solo, maaperäeläimistö, 570 Life sciences, biology, eartworm, abundance, biomass, diversity, Laboratory of Nematology, [SDE.BE]Environmental Sciences/Biodiversity and Ecology, COMMUNITIES, community ecology
Abstract

Earthworms are an important soil taxon as ecosystem engineers, providing a variety of crucial ecosystem functions and services. Little is known about their diversity and distribution at large spatial scales, despite the availability of considerable amounts of local-scale data. Earthworm diversity data, obtained from the primary literature or provided directly by authors, were collated with information on site locations, including coordinates, habitat cover, and soil properties. Datasets were required, at a minimum, to include abundance or biomass of earthworms at a site. Where possible, site-level species lists were included, as well as the abundance and biomass of individual species and ecological groups. This global dataset contains 10,840 sites, with 184 species, from 60 countries and all continents except Antarctica. The data were obtained from 182 published articles, published between 1973 and 2017, and 17 unpublished datasets. Amalgamating data into a single global database will assist researchers in investigating and answering a wide variety of pressing questions, for example, jointly assessing aboveground and belowground biodiversity distributions and drivers of biodiversity change., Measurement(s) earthworm communities • Abundance • organic material • Diversity • environmental properties Technology Type(s) digital curation Factor Type(s) location Sample Characteristic - Organism Lumbricina Sample Characteristic - Environment soil Sample Characteristic - Location global Machine-accessible metadata file describing the reported data: 10.6084/m9.figshare.13399118

Published
2021
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193. Clinical criteria for limbic-predominant age-related TDP-43 encephalopathy.

Author

Wolk DA, Nelson PT, Apostolova L, Arfanakis K, Boyle PA, Carlsson CM, Corriveau-Lecavalier N, Dacks P, Dickerson BC, Domoto-Reilly K, Dugger BN, Edelmayer R, Fardo DW, Grothe MJ, Hohman TJ, Irwin DJ, Jicha GA, Jones DT, Kawas CH, Lee EB, Lincoln K, Maestre GE, Mormino EC, Onyike CU, Petersen RC, Rabinovici GD, Rademakers R, Raman R, Rascovsky K, Rissman RA, Rogalski E, Scheltens P, Sperling RA, Yang HS, Yu L, Zetterberg H, and Schneider JA

Subjects
Humans, Alzheimer Disease pathology, Limbic System pathology, Hippocampus pathology, Aged, Dementia, TDP-43 Proteinopathies pathology
Abstract

Limbic predominant age-related TDP-43 encephalopathy neuropathologic change (LATE-NC) is highly prevalent in late life and a common co-pathology with Alzheimer's disease neuropathologic change (ADNC). LATE-NC is a slowly progressive, amnestic clinical syndrome. Alternatively, when present with ADNC, LATE-NC is associated with a more rapid course. With the emergence of anti-amyloid therapeutics, discrimination of LATE-NC from ADNC is critical and will lead to greater clinical recognition of amnestic patients without ADNC. Furthermore, co-pathology with LATE-NC may influence outcomes of these therapeutics. Thus there is a need to identify patients during life with likely LATE-NC. We propose criteria for clinical diagnosis of LATE as an initial framework for further validation. In the context of progressive memory loss and substantial hippocampal atrophy, criteria are laid out for probable (amyloid negative) or possible LATE (amyloid biomarkers are unavailable or when amyloid is present, but hippocampal neurodegeneration is out of proportion to expected pure ADNC). HIGHLIGHTS: Limbic-predominant age-related TDP-43 encephalopathy (LATE) is a highly prevalent driver of neuropathologic memory loss in late life. LATE neuropathologic change (LATE-NC) is a common co-pathology with Alzheimer's disease neuropathologic change (ADNC) and may influence outcomes with emerging disease-modifying medicines. We provide initial clinical criteria for diagnosing LATE during life either when LATE-NC is the likely primary driver of symptoms or when observed in conjunction with AD. Definitions of possible and probable LATE are provided., (© 2025 The Author(s). Alzheimer's & Dementia published by Wiley Periodicals LLC on behalf of Alzheimer's Association.)

Published
2025
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194. Circadian Gating of Thyroid Hormone Action in Hepatocytes.

Author

Lincoln K, Zhou J, Oster H, and de Assis LVM

Subjects
Animals, Mice, Thyroid Hormones metabolism, Cell Line, Fatty Liver metabolism, Fatty Liver pathology, Circadian Clocks genetics, Hepatocytes metabolism, Circadian Rhythm, Triiodothyronine pharmacology, Triiodothyronine metabolism
Abstract

Thyroid hormones, thyroxin (T 4 ) and the biologically active triiodothyronine (T 3 ), play important roles in liver metabolic regulation, including fatty acid biosynthesis, beta-oxidation, and cholesterol homeostasis. These functions position TH signaling as a potential target for the treatment of metabolic dysfunction-associated steatotic liver disease (MASLD). Elevated T 3 levels in the circulation are associated with increased hepatic lipid turnover, which is also under the control of the circadian clock system. In this study, we developed a cell system to study the impact of hepatocyte circadian rhythms on the metabolic response to T 3 treatment under control and steatotic conditions. Synchronized AML-12 circadian reporter hepatocytes were treated with T 3 at different circadian phases and metabolic conditions. T 3 treatment increased metabolic activity in a dose-independent fashion and had no significant effect on circadian rhythms in AML-12 cells. T 3 had marked time-of-treatment-dependent effects on metabolic transcript expression. Steatosis induction altered metabolic transcript expression in AML-12 cells. In this condition, the circadian rhythm period was lengthened, and this effect was independent of T 3 . Under steatotic conditions, T 3 had marked time-of-treatment dependent effects on metabolic transcript expression, which differed from those observed under control conditions. These findings reveal a time-of-day-dependent response of hepatocytes to T 3 , which is further modulated by the metabolic state. Our data suggest that time has a strong influence on liver TH action, which might be considered when treating MASLD.

Published
2024
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195. The Novel, Clinical-Stage Soluble Guanylate Cyclase Activator BI 685509 Protects from Disease Progression in Models of Renal Injury and Disease.

Author

Reinhart GA, Harrison PC, Lincoln K, Chen H, Sun P, Hill J, Qian HS, McHugh MC, Clifford H, Ng KJ, Wang H, Fowler D, Gueneva-Boucheva K, Brenneman JB, Bosanac T, Wong D, Fryer RM, Sarko C, Boustany-Kari CM, and Pullen SS

Subjects
Rats, Humans, Animals, Soluble Guanylyl Cyclase metabolism, Guanylate Cyclase metabolism, Kidney metabolism, Disease Progression, Proteinuria drug therapy, Fibrosis, Enalapril therapeutic use, Nitric Oxide metabolism, Cyclic GMP metabolism, Ureteral Obstruction pathology, Renal Insufficiency, Chronic
Abstract

Activation of soluble guanylate cyclase (sGC) to restore cyclic guanosine monophosphate (cGMP) and improve functionality of nitric oxide (NO) pathways impaired by oxidative stress is a potential treatment of diabetic and chronic kidney disease. We report the pharmacology of BI 685509, a novel, orally active small molecule sGC activator with disease-modifying potential. BI 685509 and human sGC α 1/ β 1 heterodimer containing a reduced heme group produced concentration-dependent increases in cGMP that were elevated modestly by NO, whereas heme-free sGC and BI 685509 greatly enhanced cGMP with no effect of NO. BI 685509 increased cGMP in human and rat platelet-rich plasma treated with the heme-oxidant ODQ; respective EC 50 values were 467 nM and 304 nM. In conscious telemetry-instrumented rats, BI 685509 did not affect mean arterial pressure (MAP) or heart rate (HR) at 3 and 10 mg/kg (p.o.), whereas 30 mg/kg decreased MAP and increased HR. Ten days of BI 685509 at supratherapeutic doses (60 or 100 mg/kg p.o., daily) attenuated MAP and HR responses to a single 100 mg/kg challenge. In the ZSF1 rat model, BI 685509 (1, 3, 10, and 30 mg/kg per day, daily) coadministered with enalapril (3 mg/kg per day) dose-dependently reduced proteinuria and incidence of glomerular sclerosis; MAP was modestly reduced at the higher doses versus enalapril. In the 7-day rat unilateral ureteral obstruction model, BI 685509 dose-dependently reduced tubulointerstitial fibrosis ( P < 0.05 at 30 mg/kg). In conclusion, BI 685509 is a potent, orally bioavailable sGC activator with clear renal protection and antifibrotic activity in preclinical models of kidney injury and disease. SIGNIFICANCE STATEMENT: BI 685509 is a novel small soluble guanylate cyclase (sGC) molecule activator that exhibits an in vitro profile consistent with that of an sGC activator. BI 685509 reduced proteinuria and glomerulosclerosis in the ZSF1 rat, a model of diabetic kidney disease (DKD), and reduced tubulointerstitial fibrosis in a rat 7-day unilateral ureteral obstruction model. Thus, BI 685509 is a promising new therapeutic agent and is currently in phase II clinical trials for chronic kidney disease and DKD., (Copyright © 2023 by The American Society for Pharmacology and Experimental Therapeutics.)

Published
2023
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196. The Genetic Testing Experience of Individuals with Parkinson's Disease.

Author

Richards S, Mu W, Nusbaum R, Lincoln K, and Solimine J

Abstract

Background: The perspective and experiences of individuals with Parkinson's disease (PD) regarding genetic testing is limited., Objectives: To determine if anticipated benefits and negative consequences of genetic testing noted in prior studies have occurred in a surveyed group of patients with PD and to identify reasons why some individuals with PD have not had testing., Methods: Individuals were surveyed from 22 support/advocacy groups throughout the US. Information about patient demographics and genetic testing were assessed, along with the consequences experienced after testing or anticipated by those who have not had testing. Descriptive statistics, Pearson correlation coefficient, ANOVA, and independent sample t -test were utilized for data analysis., Results: Of the genetic testing group ( n  = 78), most received testing through a research study (44.9%) or a Direct-to-Consumer company (46.2%). Most did not meet with a genetic counselor before (87.2%) or after testing (64.1%). Fewer positive and fewer negative consequences were reported after testing compared to the consequences anticipated by those who have not undergone testing ( P  < 0.001, all comparisons). Of the non-genetic testing group ( n  = 166), 49.4% did not undergo testing because they were not aware it was available and 38.0% because their doctor did not offer it., Conclusions: Findings demonstrate the need for providers to have genetic testing discussions with PD patients, who may otherwise seek testing via Direct-to-Consumer companies or be unaware it is available. Collaborations with genetic counselors trained in providing anticipatory guidance may assist patients in forming more realistic expectations regarding the consequences experienced after genetic testing for PD., (© 2022 International Parkinson and Movement Disorder Society.)

Published
2023
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197. Perceived colorism and lifetime psychiatric disorders among Black American adults: findings from the National Survey of American Life.

Author

Oh H, Lincoln K, and Waldman K

Subjects
Adult, Black or African American, Anxiety Disorders epidemiology, Humans, United States epidemiology, Feeding and Eating Disorders, Stress Disorders, Post-Traumatic, Substance-Related Disorders
Abstract

Colorism has been propagated across the globe, and skin tone discrimination may partly explain social stratification and health disparities within the Black American population. Using data from a large probability sample of Black American adults (National Survey of American Life; 2001-2003), we examined the relations between perceived colorism and psychiatric disorders. In multivariable logistic regression models, in-group colorism was associated with greater odds of having any lifetime psychiatric disorder (aOR: 1.20; 95% CI: 1.08-1.32; p = 0.00); however, out-group colorism was not significantly associated, net of sociodemographic characteristics and in-group colorism (aOR: 1.08; 95% CI: 0.99-1.18; p = 0.08). When looking at specific disorders, in-group colorism was significantly associated with greater odds of alcohol use disorder, substance use disorder, anxiety disorder, and eating disorder, but was not associated with post-traumatic stress disorder or mood disorder. Out-group colorism was not significantly associated with any psychiatric disorder except anxiety disorder. Our findings show that colorism predicts psychiatric disorders, though more research is needed to understand why the effects of in-group and out-group colorism are related to certain psychiatric disorders but not others., (© 2021. Springer-Verlag GmbH Germany, part of Springer Nature.)

Published
2021
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198. Church-Based Exchanges of Informal Social Support among African Americans.

Author

Taylor RJ, Chatters LM, Lincoln K, and Woodward AT

Abstract

This study examines the correlates of the types of instrumental support exchanges that occur between church members among African Americans. Exchanges of four types of instrumental support are examined: transportation assistance, help with chores, financial assistance and help during illness. Data for this study are from the National Survey of American Life Re-Interview, the follow-up survey to the National Survey of American Life which is a nationally representative sample of the African American population. We found that African Americans were more likely to both give and receive support in situations involving illness, followed by transportation, financial assistance, and help with chores. For each of the four types of instrumental support, respondents indicate that they provide more assistance to others than they receive. For all eight dependent variables, those with lower levels of education were more actively engaged in receiving and providing support than their higher educated counterparts. Higher levels of religious service attendance were associated with higher levels of support, which underscores the importance of involvement in faith communities for assistance. Overall, our findings confirm the importance of church-based informal social support between African Americans and documents within group diversity as both recipients and providers of assistance.

Published
2017
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199. Wound Care Centers: Critical Thinking and Treatment Strategies for Wounds

Author

de Leon J, Bohn GA, DiDomenico L, Fearmonti R, Gottlieb HD, Lincoln K, Shah JB, Shaw M, Taveau HS IV, Thibodeaux K, Thomas JD, and Treadwell TA

Subjects
Debridement, Delivery of Health Care, Integrated, Humans, Practice Guidelines as Topic, Wound Healing drug effects, Anti-Bacterial Agents therapeutic use, Biofilms drug effects, Wound Infection microbiology, Wound Infection therapy, Wounds and Injuries microbiology, Wounds and Injuries therapy
Abstract

Many wound care centers (WCCs) provide a specialized level of care using various wound care therapies and are managed by quali ed healthcare professionals (QHPs) from di erent specialty backgrounds such as family medicine, podiatry, and plastic surgery. However, these QHPs are sometimes challenged by reimbursement issues, limited therapy and dressing options, reduced access to multidisciplinary team members, and cost-driven factors unique to WCCs. To help address these issues, a meeting was convened by an expert panel of WCC physicians to discuss best practices for treating complex patients in a WCC. This publication presents an overview of WCC chal- lenges, describes a holistic approach to treating WCC patients, and provides clinical guidance on the decision-mak- ing process for selecting optimal treatment plans for the WCC patient. Clinical cases of atypical, surgical and chronic wounds seen in a WCC are also presented.

Published
2016

200. Evaluation of Epidermal Skin Grafts for the Treatment of Complex Wounds in a Wound Care Center: A 94-Patient Case Series.

Author

Lincoln K and Hyde J

Subjects
Adult, Aged, Epidermis transplantation, Female, Graft Survival, Humans, Lost to Follow-Up, Male, Middle Aged, Practice Guidelines as Topic, Tissue and Organ Harvesting, Treatment Outcome, Wound Healing, Wounds and Injuries pathology, Debridement methods, Skin Transplantation, Trauma Centers, Wounds and Injuries therapy
Abstract

Background: In recent years, a new technology for autologous epidermal harvesting has been developed to produce epidermal skin grafts (ESGs) for use over wounds. This technology employs negative pressure and heat to raise the epidermal skin layer, allowing for consistent and reproducible epidermal harvesting. The aim of this case series is to present the authors' experience using an automated, epidermal harvesting system to produce ESGs to treat wounds of patients with multiple comorbidities., Materials and Methods: This case series was conducted between January 1, 2013 and December 31, 2014. Patients with wounds (≤ 25 cm2) that failed to heal were treated with ESGs by a group of 3 wound care physicians in 2 outpatient wound care centers in a community health center setting., Results: A total of 94 patients with 102 wounds were identified. Of the 94 patients, 3 were noncompliant and 9 were lost to follow-up. Therefore, 82 patients with 90 wounds were included in the analysis. The majority of wounds demonstrated epithelialization (83/90, 92.2%). Of the 90 wounds, 75 (83.3%) healed following epidermal grafting, 4 (4.4%) wounds displayed improvement, and 11 (12.2%) did not heal. Minimal or no pain at the donor site was reported by the patients, and all donor sites healed without complications., Conclusion: This case series provides additional evidence for the use of ESGs for the treatment of wounds that fail to heal.

Published
2016

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