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710 results on '"Karimi, Maryam"'

151. Effects of ambient temperature on COPD symptoms and exacerbations in the SubPopulations and InteRmediate Outcome Measures In COPD Study (SPIROMICS) cohort

Author

Gupta, Supaksh, primary, Sack, Coralynn, additional, Paulin, Laura, additional, Gassett, Amanda, additional, Sung, Clifford, additional, Hess, Jeremy, additional, Woodruff, Prescott, additional, Dransfield, Mark, additional, Paine, Robert, additional, Barjaktarevic, Igor, additional, Comellas, Alejandro, additional, Karimi, Maryam, additional, Pirozzi, Cheryl, additional, Ortega, Victor, additional, Labaki, Wassim, additional, Bhatt, Surya, additional, Hansel, Nadia, additional, and Kaufman, Joel, additional

Published
2021
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161. Maintenance targeted therapy compared to standard of care (SoC) in patients (pts) with metastatic non-small cell lung cancer (NSCLC): Results from the phase II randomized UNICANCER/IFCT1301- SAFIR02-LUNG intergroup trial.

Author

Besse, Benjamin, primary, Karimi, Maryam, additional, Tomasini, Pascale, additional, Janicot, Henri, additional, Raimbourg, Judith, additional, Audigier-Valette, Clarisse, additional, Madroszyk, Anne, additional, Chomy, Francois, additional, Dansin, Eric, additional, Mazieres, Julien, additional, Cortot, Alexis, additional, Bieche, Ivan, additional, Lacroix, Ludovic, additional, Boyault, Sandrine, additional, Soubeyran, Isabelle, additional, Morel, Alain, additional, Tran-Dien, Alicia, additional, Jacquet, Alexandra, additional, Soria, Jean-Charles, additional, and Barlesi, Fabrice, additional

Published
2021
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163. Generative adversarial networks applied to uncooperative microwave imaging system calibration

Author

McLeod, Robert (Electrical and Computer Engineering) Asefi, Mohammad (Electrical and Computer Egnineering), Gilmore, Colin (Electrical and Computer Engineering) Jeffrey, Ian (Electrical and Computer Engineering), Karimi, Maryam, McLeod, Robert (Electrical and Computer Engineering) Asefi, Mohammad (Electrical and Computer Egnineering), Gilmore, Colin (Electrical and Computer Engineering) Jeffrey, Ian (Electrical and Computer Engineering), and Karimi, Maryam

Abstract

Harvested grain is generally stored in large bins. The quality and quantity of stored grain are important as seeds may be threatened by molds, sprouting, insects, or small animals. Therefore monitoring bin contents is critical. Electromagnetic imaging has recently been proposed as a method to monitor bin contents. For example, trained regression Machine Learning (ML) models are capable of extracting bulk parameters of the grain within the bin (i.e., grain height, cone angle, and bulk real-imaginary permittivity). Knowledge of the permittivity can be mapped to moisture and allows inference of potential stored losses and planning of mitigating action. Unfortunately, training these models requires a large labeled dataset. Obtaining such a dataset for experimental installations is unfeasible, and generating synthetic datasets is time-consuming. In this thesis, we investigate the application of Generative Adversarial Networks (GANs) to electromagnetic imaging for grain storage. GANs are designed to generate data of a particular type, and once trained, GANs can be used to generate data in an inexpensive way. Also, a recent GAN variant, the CycleGAN, has been proposed to transfer data from one domain to another. Such functionality is applicable to the electromagnetic imaging problem of calibration. We propose and answer two research questions. First, whether or not a simple 1DGAN can be used for data augmentation and second, whether or not a CycleGAN can be used for calibrating uncooperative imaging systems. Results show that a 1D-GAN is too simple to be used for data augmentation as transmitter-receiver ordering is not preserved. The 1D-GAN is demonstrated to produce data with similar distributions to real data, which suggests that with appropriate architectural modifications the idea is sound. Preliminary tests on faux-experimental data show that the CycleGAN has promised to serve as a calibration method, with the successful recovery of bulk parameters demonstrated to wi

Published
2021

168. Characterization of disulfide (cystine) oxidation by HOCl in a model peptide:Evidence for oxygen addition, disulfide bond cleavage and adduct formation with thiols

Author

Karimi, Maryam, Crossett, Ben, Cordwell, Stuart J., Pattison, David I., Davies, Michael J., Karimi, Maryam, Crossett, Ben, Cordwell, Stuart J., Pattison, David I., and Davies, Michael J.

Abstract

Disulfide bonds play a key role in stabilizing proteins by cross-linking secondary structures. Whilst many disulfides are effectively unreactive, it is increasingly clear that some disulfides are redox active, participate in enzymatic reactions and/or regulate protein function by allosteric mechanisms. Previously (Karimi et al., Sci. Rep. 2016, 6, 38752) we have shown that some disulfides react rapidly with biological oxidants due to favourable interactions with available lone-pairs of electrons. Here we present data from kinetic, mechanistic and product studies for HOCl-mediated oxidation of a protected nine-amino acid model peptide containing a N- to C-terminal disulfide bond. This peptide reacts with HOCl with k2 1.8 × 106 M−1 s−1, similar to other highly-reactive disulfide-containing compounds. With low oxidant excesses, oxidation yields multiple oxidation products from the disulfide, with reaction predominating at the N-terminal Cys to give sulfenic, sulfinic and sulfonic acids, and disulfide bond cleavage. Limited oxidation occurs, with higher oxidant excesses, at Trp and His residues to give mono- and di- (for Trp) oxygenated products. Site-specific backbone cleavage also occurs between Arg and Trp, probably via initial side-chain modification. Treatment of the previously-oxidised peptide with thiols (GSH, N-Ac-Cys), results in adduction of the thiol to the oxidised peptide, with this occurring at the original disulfide bond. This gives an open-chain peptide, and a new mixed disulfide containing GSH or N-Ac-Cys as determined by mass spectrometry. Disulfide bond oxidation may therefore markedly alter the structure, activity and function of disulfide-containing proteins, and provides a potential mechanism for protein glutathionylation.

Published
2020

169. Perception of Musical Emotion in the Students with Cognitive and Acquired Hearing Loss

Author

MAZAHERYAZDI, Malihe, AGHASOLEIMANI, Mina, KARIMI, Maryam, and ARJMAND, Pirooz

Subjects
Emotion, Acquired hearing loss, otorhinolaryngologic diseases, Original Article, Deafness, Children, Music
Abstract

Objective Hearing loss can affect the perception of emotional reaction to the music. The present study investigated whether the students with congenital hearing loss exposed to the deaf culture, percept the same emotion from the music as students with acquired hearing loss. Materials & Methods Participants were divided into two groups; 30 students with bilaterally congenital moderate to severe hearing loss that were selected from deaf schools located in Tehran, Iran and 30 students with an acquired hearing loss with the same degree of hearing loss selected from Amiralam Hospital, Tehran, Iran and compared with the group of 30 age and gender-matched normal hearing subjects served our control in 2012. The musical stimuli consisted of three different sequences of music, (sadness, happiness, and fear) each with the duration of 60 sec. The students were asked to point to the lists of words that best matched with their emotions. Results Emotional perception of sadness, happiness, and fear in congenital hearing loss children was significantly poorly than acquired hearing loss and normal hearing group (P

Published
2018

175. List of contributors

Author

Aparna, Asok, Appukuttan, Saritha, Arora, Arun, Barua, Shaswat, Baruah, Swagata, Besta, Chandra Shekar, Bhaliya, Jaydip, Chandran, Akash M., Chauhan, Jitendra, Chugh, K.W., Emdadi, Babak, Farzizada, Zeynab, Gahlot, Swati, Ghahramani, Maral, Ghare Tepeh, Elmira Abbasi, Ghasem, Nayef, Hajiyev, Matlab, Hao, Ming, Hooshyari, Khadijeh, Huang, Juan, Jamalpour, Seifollah, Jayan, Jitha S., Jiang, Shan, Kalita, Devaleena, Karimi, Maryam, Katariya, Hitesh, Konwar, Papuli, Krishna, Hemanth, Kulshrestha, Vaibhav, Lekshmi, A.G., Liu, Yanbo, Mahale, Rayappa Shrinivas, Mahjub, Alireza, Mahjub, Hoda, Maroufkhani, Mahshid, Mhaske, S.T., Mirzaliyev, Seymur, Mishra, Suvrajyoti, Mohanty, J.D., Moradi, Rasoul, Mural, Prasanna Kumar S., Musayev, Rashad, Nobakht, Danial, Patel, Gautam, Pourhossein, Atefeh, Rahmani, Shahrzad, Ramadoss, Ananthakumar, Ramakrishna, Seeram, Ramesh, G.V., Rana, Shilpa, Rastgoo-Deylami, Mohadese, Rathod, Babarao Sitaram, Reddy, N. Mahendar, Sahu, Debojeet, Saritha, D., Sethulekshmi, A.S., Shah, Vraj, Sharath, P.C., Sharma, Himani, Shashanka, R., Singh, Bharti, Singh, Vishal, Sreehari, H., Suthar, Vaishali, Tamilvanan, Siva, Tamrakar, Raunak Kumar, Tamsilian, Yousef, Tohidian, Mahdi, Tripathy, Alekhika, Upadhyay, Kanchan, Vakili, Helma, Varghese, Lity Alen, Varun, S., Vasanth, Shamanth, Vasantha Kumar, S.N., Venu, Gopika, Vindhyasurumi, A., Yang, Bo, Yerolla, Raju, Yusifov, Rasim, and Zhang, Tianyi

Published
2023
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180. Construction of A Synthetic Gene Encoding the Multi-Epitope of Toxoplasma gondii and Demonstration of the Relevant Recombinant Protein Production: A Vaccine Candidate

Author

Karimi, Maryam, primary, Seyyed Tabaei, Seyyed Javad, additional, Ranjbar, Mohammad Mehdi, additional, Fathi, Fardin, additional, Jalili, Ali, additional, Zamini, Ghasem, additional, Javadi Mamaghani, Amirreza, additional, Nazari, Javad, additional, Roshani, Daem, additional, Bagherani, Nooshin, additional, and Khademerfan, Mohammadbagher, additional

Published
2020
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186. Role of the total mutation burden (TMB) and tumor-infiltrating lymphocytes (TILs) on the development of second primary cancer after complete resection of non-small cell lung cancer (NSCLC).

Author

Gauthier, Marie-Pier, primary, Karimi, Maryam, additional, Michiels, Stefan, additional, Seymour, Lesley, additional, Brambilla, Elisabeth, additional, Le Chevalier, Thierry, additional, Soria, Jean-Charles, additional, Kratzke, Robert Arthur, additional, Graziano, Stephen L., additional, Govindan, Ramaswamy, additional, Tsao, Ming-Sound, additional, and Shepherd, Frances A., additional

Published
2020
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187. Prognostic and predictive effect of KRAS gene copy number and mutation status in early stage non-small cell lung cancer (NSCLC) patients.

Author

Fung, Andrea S., primary, Karimi, Maryam, additional, Michiels, Stefan, additional, Seymour, Lesley, additional, Brambilla, Elisabeth, additional, Le Chevalier, Thierry, additional, Soria, Jean-Charles, additional, Kratzke, Robert Arthur, additional, Graziano, Stephen L., additional, Devarakonda, Siddhartha, additional, Govindan, Ramaswamy, additional, Tsao, Ming-Sound, additional, and Shepherd, Frances A., additional

Published
2020
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189. Viral DNA Binding Protein SUMOylation Promotes PML Nuclear Body Localization Next to Viral Replication Centers

Author

Stubbe, Miona, primary, Mai, Julia, additional, Paulus, Christina, additional, Stubbe, Hans Christian, additional, Berscheminski, Julia, additional, Karimi, Maryam, additional, Hofmann, Samuel, additional, Weber, Elisabeth, additional, Hadian, Kamyar, additional, Hay, Ron, additional, Groitl, Peter, additional, Nevels, Michael, additional, Dobner, Thomas, additional, and Schreiner, Sabrina, additional

Published
2020
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198. Robust effect of metabolic syndrome on major metabolic pathways in the myocardium

Author

Karimi, Maryam, primary, Pavlov, Vasile I., additional, Ziegler, Olivia, additional, Sriram, Nivedita, additional, Yoon, Se-Young, additional, Agbortoko, Vahid, additional, Alexandrova, Stoiana, additional, Asara, John, additional, Sellke, Frank W., additional, Sturek, Michael, additional, Feng, Jun, additional, Alexandrov, Boian S., additional, and Usheva, Anny, additional

Published
2019
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