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153. Isolated Verrucous Mycosis Fungoides with an Etiological Clue

Author

Ikuno, Yasuaki, Kokubu, Hiraku, Yamaguchi, Akihiko, Takahashi, Toshifumi, Kato, Takeshi, and Fujimoto, Noriki

Subjects
Mycoses, Mycosis fungoides
Abstract

Author(s): Yasuaki Ikuno [1]; Hiraku Kokubu [1]; Akihiko Yamaguchi [1]; Toshifumi Takahashi [1]; Takeshi Kato [1]; Noriki Fujimoto [1] Dear Editor, A 54-year-old Japanese man noticed itchy erythematous plaques on [...]

Published
2023
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154. Capecitabine versus S-1 as adjuvant chemotherapy for patients with stage III colorectal cancer (JCOG0910): an open-label, non-inferiority, randomised, phase 3, multicentre trial

Author

Hamaguchi, Tetsuya, Shimada, Yasuhiro, Mizusawa, Junki, Kinugasa, Yusuke, Kanemitsu, Yukihide, Ohue, Masayuki, Fujii, Shoichi, Takiguchi, Nobuhiro, Yatsuoka, Toshimasa, Takii, Yasumasa, Ojima, Hitoshi, Masuko, Hiroyuki, Kubo, Yoshiro, Mishima, Hideyuki, Yamaguchi, Takashi, Bando, Hiroyuki, Sato, Toshihiko, Kato, Takeshi, Nakamura, Kenichi, Fukuda, Haruhiko, and Moriya, Yoshihiro

Published
2018
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155. Safety data from the phase III Japanese ACHIEVE trial: part of an international, prospective, planned pooled analysis of six phase III trials comparing 3 versus 6 months of oxaliplatin-based adjuvant chemotherapy for stage III colon cancer

Author

Kotaka, Masahito, Yamanaka, Takeharu, Yoshino, Takayuki, Manaka, Dai, Eto, Tetsuya, Hasegawa, Junichi, Takagane, Akinori, Nakamura, Masato, Kato, Takeshi, Munemoto, Yoshinori, Nakamura, Fumitaka, Bando, Hiroyuki, Taniguchi, Hiroki, Gamoh, Makio, Shiozawa, Manabu, Saji, Shigetoyo, Maehara, Yoshihiko, Mizushima, Tsunekazu, Ohtsu, Atsushi, and Mori, Masaki

Published
2018
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158. PS4-4 Early tumor shrinkage and depth of response with first-line panitumumab or bevacizumab and mFOLFOX treatment in PARADIGM

Author

Muro, Kei, primary, Watanabe, Jun, additional, Shitara, Kohei, additional, Yamazaki, Kentaro, additional, Ohori, Hisatsugu, additional, Shiozawa, Manabu, additional, Yasui, Hirofumi, additional, Oki, Eiji, additional, Sato, Takeo, additional, Naito, Takeshi, additional, Komatsu, Yoshito, additional, Kato, Takeshi, additional, Hihara, Masamitsu, additional, Soeda, Junpei, additional, Yamamoto, Kouji, additional, Akagi, Kiwamu, additional, Ochiai, Atsushi, additional, Tsuchihara, Katsuya, additional, and Yoshino, Takayuki, additional

Published
2023
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159. O4-5 Circulating tumor DNA dynamics as an early predictor of recurrence in patients with radically resected colorectal cancer: GALAXY study in the CIRCULATE-Japan

Author

Mishima, Saori, primary, Kotani, Daisuke, additional, Nakamura, Yoshiaki, additional, Bando, Hideaki, additional, Miyo, Masaaki, additional, Hamabe, Atsushi, additional, Watanabe, Jun, additional, Hirata, Keiji, additional, Akazawa, Naoya, additional, Kataoka, Kozo, additional, Yeh, Kun-Huei, additional, Laliotis, George, additional, Jurdi, Adham, additional, Liu, Minetta, additional, Taniguchi, Hiroya, additional, Takemasa, Ichiro, additional, Kato, Takeshi, additional, Yoshino, Takayuki, additional, and Oki, Eiji, additional

Published
2023
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161. Multicenter prospective observational study to clarify the current status and clinical outcome in Japanese patients who have an indication for implantable cardioverter defibrillator (ICD) or wearable cardioverter defibrillator (WCD) (TRANSITION JAPAN‐ICD/WCDstudy): Rationale and design of a prospective, multicenter, observational, comparative study

Author

Ikeya, Yukitoshi, Okumura, Yasuo, Kogawa, Rikitake, Nagashima, Koichi, Nakai, Toshiko, Yokoyama, Katsuaki, Iso, Kazuki, Kato, Takeshi, Tsuda, Toyonobu, Tachibana, Eizo, Hayashida, Satoshi, Fukaya, Hidehira, Ishizue, Naruya, Hayashi, Hidemori, Kuroda, Shunsuke, Sonoda, Kazumasa, Nakahara, Shiro, Hori, Yuichi, Harada, Masahide, Murakami, Masato, Iwasaki, Yu‐Ki, Aizawa, Yoshiyasu, Shimizu, Wataru, Fukamizu, Seiji, Takami, Mitsuru, Kusano, Kengo, Ishibashi, Kohei, Harada, Tomoo, Nakajima, Ikutaro, Tabuchi, Haruna, Kunimoto, Mitsuhiro, Shoda, Morio, Higuchi, Satoshi, Morishima, Itsuro, Kanzaki, Yasunori, Kato, Ritsushi, Ikeda, Yoshifumi, Makimoto, Hisaki, Kabutoya, Tomoyuki, Kario, Kazuomi, Arimoto, Takanori, Ninomiya, Yuichi, Yoshimoto, Issei, Sasaki, Shingo, Kondo, Yusuke, Chiba, Toshinori, Yamashita, Kennosuke, Mizuno, Yosuke, Inoue, Masaru, Ueyama, Takeshi, Koyama, Jyunjiro, Tsurugi, Takuo, Orita, Yoshiya, Asano, Taku, Shinke, Toshiro, Tanno, Kaoru, and Murotani, Kenta

Abstract

Despite the positive impact of implantable cardioverter defibrillators (ICDs) and wearable cardioverter defibrillators (WCDs) on prognosis, their implantation is often withheld especially in Japanese heart failure patients with reduced left ventricular ejection fraction (HFrEF) who have not experienced ventricular tachycardia (VT) or ventricular fibrillation (VF) for uncertain reasons. Recent advancements in heart failure (HF) medications have significantly improved the prognosis for HFrEF. Given this context, a critical reassessment of the treatment and prognosis of ICDs and WCDs is essential, as it has the potential to reshape awareness and treatment strategies for these patients. We are initiating a prospective multicenter observational study for HFrEF patients eligible for ICD in primary and secondary prevention, and WCD, regardless of device use, including all consenting patients. Study subjects are to be enrolled from 31 participant hospitals located throughout Japan from April 1, 2023, to December 31, 2024, and each will be followed up for 1 year or more. The planned sample size is 651 cases. The primary endpoint is the rate of cardiac implantable electronic device implementation. Other endpoints include the incidence of VT/VF and sudden death, all‐cause mortality, and HF hospitalization, other events. We will collect clinical background information plus each patient's symptoms, Clinical Frailty Scale score, laboratory test results, echocardiographic and electrocardiographic parameters, and serial changes will also be secondary endpoints. Not applicable. This study offers invaluable insights into understanding the role of ICD/WCD in Japanese HF patients in the new era of HF medication. The TRANSITION JAPAN‐ICD/WCD study explores the clinical outcomes of Japanese HFrEF patients meeting implantable cardioverter defibrillator (ICD) and wearable cardioverter defibrillator (WCD) criteria, including those who choose or decline device implantation, to assess the ICD/WCD current status after the introduction of new heart failure drugs like SGLT2i or ARNi in Japan.

Published
2024
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165. Protocol of the QUATTRO-II study: a multicenter randomized phase II study comparing CAPOXIRI plus bevacizumab with FOLFOXIRI plus bevacizumab as a first-line treatment in patients with metastatic colorectal cancer

Author

Miyo, Masaaki, Kato, Takeshi, Yoshino, Takayuki, Yamanaka, Takeharu, Bando, Hideaki, Satake, Hironaga, Yamazaki, Kentaro, Taniguchi, Hiroya, Oki, Eiji, Kotaka, Masahito, Oba, Koji, Miyata, Yoshinori, Muro, Kei, Komatsu, Yoshito, Baba, Hideo, and Tsuji, Akihito

Published
2020
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167. WE economy: Potential of mutual aid distribution based on moral responsibility and risk vulnerability.

Author

Kato, Takeshi

Subjects
MUTUAL aid, RESPONSIBILITY, WEALTH inequality, WEALTH distribution, ECONOMIC systems
Abstract

Reducing wealth inequality is a global challenge that requires the transformation of the economic systems that produce inequality. The economic system comprises: (1) gifts and reciprocity, (2) power and redistribution, (3) market exchange, and (4) mutual aid without reciprocal obligations. Current inequality stems from a capitalist economy consisting of (2) and (3). To sublimate (1), the human economy, to (4), the concept of a "mixbiotic society" has been proposed in the philosophical realm. In this society, free and diverse individuals mix, recognize their respective "fundamental incapability," and sublimate them into "WE" solidarity. Moreover, the economy must have a moral responsibility as a co-adventurer and consider its vulnerability to risk. This study focuses on two factors of mind perception—moral responsibility and risk vulnerability—and proposes a novel wealth distribution model between the two agents following an econophysical approach, whereas the conventional model dealt with redistribution through taxes and institutions. Three models are developed: a joint-venture model in which profit/losses are distributed based on their factors, a redistribution model in which wealth stocks are redistributed periodically based on their factors in the joint-venture model, and a "WE economy" model in which profit/losses are distributed based on the ratio of each other's factors. A simulation comparison reveals that WE economies are effective in reducing inequality, resilient in normalizing wealth distribution as advantages, and susceptible to free riders as disadvantages. However, this disadvantage can be compensated for by fostering fellowship and using joint ventures. This study presents the effectiveness of moral responsibility and risk vulnerability, complementarity between the WE economy and joint economy, and the direction of the economy in reducing inequality. Future challenges include developing an advanced model based on real economic analysis and economic psychology and promoting its fieldwork for worker coops and platform cooperatives to realize a desirable mixbiotic society. [ABSTRACT FROM AUTHOR]

Published
2024
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170. Correction to: A placebo‑controlled, double‑blind, randomized study of recombinant thrombomodulin (ART‑123) to prevent oxaliplatin‑induced peripheral neuropathy

Author

Kotaka, Masahito, Saito, Yoji, Kato, Takeshi, Satake, Hironaga, Makiyama, Akitaka, Tsuji, Yasushi, Shinozaki, Katsunori, Fujiwara, Toshiyoshi, Mizushima, Tsunekazu, Harihara, Yasushi, Nagata, Naoki, Kurihara, Naoto, Ando, Masahiko, Kusakawa, Genichi, Sakai, Takumi, Uchida, Yugo, Takamoto, Mikihiro, Kimoto, Saki, and Hyodo, Ichinosuke

Published
2021
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173. Phase II trial of capecitabine plus oxaliplatin (CAPOX) as perioperative therapy for locally advanced rectal cancer

Author

Nishimura, Junichi, Hasegawa, Junichi, Kato, Takeshi, Yoshioka, Shinichi, Noura, Shingo, Kagawa, Yoshinori, Yasui, Masayoshi, Ikenaga, Masakazu, Murata, Kohei, Hata, Taishi, Matsuda, Chu, Mizushima, Tsunekazu, Yamamoto, Hirofumi, Doki, Yuichiro, Mori, Masaki, and Clinical Study Group of Osaka University (CSGO) Colorectal Group

Published
2018
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174. Role of plasma angiogenesis factors in the efficacy of first‐line chemotherapy combined with biologics in RAS wild‐type metastatic colorectal cancer: Results from the GI‐SCREEN CRC‐Ukit study

Author

Yuki, Satoshi, primary, Yamazaki, Kentaro, additional, Sunakawa, Yu, additional, Taniguchi, Hiroya, additional, Bando, Hideaki, additional, Shiozawa, Manabu, additional, Nishina, Tomohiro, additional, Yasui, Hisateru, additional, Kagawa, Yoshinori, additional, Takahashi, Naoki, additional, Denda, Tadamichi, additional, Esaki, Taito, additional, Kawakami, Hisato, additional, Satake, Hironaga, additional, Takashima, Atsuo, additional, Matsuhashi, Nobuhisa, additional, Kato, Takeshi, additional, Asano, Chiharu, additional, Abe, Yukiko, additional, Nomura, Shogo, additional, and Yoshino, Takayuki, additional

Published
2023
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176. Microbiome landscape and association with response to immune checkpoint inhibitors in advanced solid tumors: SCRUM-Japan MONSTAR-SCREEN

Author

NAKAMURA, YOSHIAKI, primary, Sawada, Kentaro, additional, Yamashita, Riu, additional, Sakai, Shunsuke, additional, Horasawa, Satoshi, additional, Yoshikawa, Ayumu, additional, Fujisawa, Takao, additional, Kadowaki, Shigenori, additional, Kato, Ken, additional, Ueno, Makoto, additional, Oki, Eiji, additional, Komatsu, Yoshito, additional, Chiyoda, Tatsuyuki, additional, Horita, Yosuke, additional, Yasui, Hisateru, additional, Denda, Tadamichi, additional, Satake, Hironaga, additional, Esaki, Taito, additional, Sato, Taroh, additional, Takahashi, Naoki, additional, Yamazaki, Kentaro, additional, Matsuhashi, Nobuhisa, additional, Nishina, Tomohiro, additional, Takeda, Hiroyuki, additional, Ohtsubo, Koushiro, additional, Ohta, Takashi, additional, Tsuji, Akihito, additional, Goto, Masahiro, additional, Kato, Takeshi, additional, Bando, Hideaki, additional, Tsuchihara, Katsuya, additional, and Yoshino, Takayuki, additional

Published
2023
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177. Mutational spectrum of TP53 gene correlates with nivolumab treatment efficacy in advanced gastric cancer (TP53MUT study)

Author

Ando, Koji, primary, Nakamura, Yoshiaki, additional, Kitao, Hiroyuki, additional, Shimokawa, Mototsugu, additional, Kotani, Daisuke, additional, Bando, Hideaki, additional, Nishina, Tomohiro, additional, Yamada, Takanobu, additional, Yuki, Satoshi, additional, Narita, Yukiya, additional, Hara, Hiroki, additional, Ohta, Takashi, additional, Esaki, Taito, additional, Hamamoto, Yasuo, additional, Kato, Ken, additional, Yamamoto, Yoshiyuki, additional, Minashi, Keiko, additional, Ohtsubo, Koushiro, additional, Izawa, Naoki, additional, Kawakami, Hisato, additional, Kato, Takeshi, additional, Satoh, Taroh, additional, Okano, Naohiro, additional, Tsuji, Akihito, additional, Yamazaki, Kentaro, additional, Yoshino, Takayuki, additional, Maehara, Yoshihiko, additional, and Oki, Eiji, additional

Published
2023
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178. Artificial intelligence (AI)-powered HER2 quantification continuous score (QCS) and tumor microenvironment (TME) analysis in HER2-amplified metastatic colorectal cancer (mCRC) treated with pertuzumab plus trastuzumab.

Author

Imai, Mitsuho, primary, Nakamura, Yoshiaki, additional, Okamoto, Wataru, additional, Kato, Takeshi, additional, Esaki, Taito, additional, Kato, Ken, additional, Komatsu, Yoshito, additional, Yuki, Satoshi, additional, Masuishi, Toshiki, additional, Nishina, Tomohiro, additional, Sato, Akihiro, additional, Kuwata, Takeshi, additional, Yamashita, Riu, additional, Fujisawa, Takao, additional, Bando, Hideaki, additional, Park, Jongchan, additional, Shin, Seunghwan, additional, Ock, Chan-Young, additional, Fujii, Satoshi, additional, and Yoshino, Takayuki, additional

Published
2023
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179. Postoperative circulating tumor DNA-based molecular residual disease in patients with BRAF V600E and MSI-H colorectal cancer: Updated results from GALAXY study in the CIRCULATE-Japan.

Author

Watanabe, Jun, primary, Oki, Eiji, additional, Kotani, Daisuke, additional, Nakamura, Yoshiaki, additional, Mishima, Saori, additional, Bando, Hideaki, additional, Yukami, Hiroki, additional, Ando, Koji, additional, Miyo, Masaaki, additional, Hirata, Keiji, additional, Akazawa, Naoya, additional, Yeh, Kun-Huei, additional, Laliotis, George, additional, Jurdi, Adham A, additional, Liu, Minetta, additional, Taniguchi, Hiroya, additional, Takemasa, Ichiro, additional, Kato, Takeshi, additional, Mori, Masaki, additional, and Yoshino, Takayuki, additional

Published
2023
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180. First-line (1L) panitumumab (PAN) vs bevacizumab (BEV) in patients (pts) with HER2 amplification (HER2amp+), RAS wild type (WT) metastatic colorectal cancer (mCRC) according to tumor sidedness.

Author

Oki, Eiji, primary, Muro, Kei, additional, Watanabe, Jun, additional, Shitara, Kohei, additional, Yamazaki, Kentaro, additional, Ohori, Hisatsugu, additional, Shiozawa, Manabu, additional, Yasui, Hirofumi, additional, Sato, Takeo, additional, Naito, Takeshi, additional, Komatsu, Yoshito, additional, Kato, Takeshi, additional, Soeda, Junpei, additional, Yamamoto, Kouji, additional, Yamashita, Riu, additional, Akagi, Kiwamu, additional, Ochiai, Atsushi, additional, Uetake, Hiroyuki, additional, Tsuchihara, Katsuya, additional, and Yoshino, Takayuki, additional

Published
2023
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181. Exploratory study on quantitative assessment of skin hardness in patients with systemic sclerosis using SOFTGRAM

Author

Kokubu, Hiraku, primary, Ikuno, Yasuaki, additional, Uchiyama, Kazuyuki, additional, Kato, Miwa, additional, Yamamoto, Mayuka, additional, Asada, Haruki, additional, Rikitake, Satona, additional, Kobayashi, Yoshimichi, additional, Tsukamoto, Yudai, additional, Koike, Takahiro, additional, Sugiura, Syuji, additional, Maeda, Yasuhiro, additional, Hayami, Takuma, additional, Yoneta, Kensuke, additional, Takahashi, Toshifumi, additional, Yamamoto, Bunpei, additional, Kato, Takeshi, additional, Kunisaki, Yoshito, additional, Nakatani, Makoto, additional, Okamoto, Kohei, additional, and Fujimoto, Noriki, additional

Published
2023
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185. Efficacy and safety of futibatinib for refractory advanced solid malignancies with FGFR alterations identified in circulating tumor DNA: TiFFANY, A GOZILA-affiliated Trial.

Author

Jogo, Tomoko, primary, Shinozaki, Eiji, additional, Masuishi, Toshiki, additional, Kato, Takeshi, additional, Nishina, Tomohiro, additional, Esaki, Taito, additional, Komatsu, Yoshito, additional, Kato, Ken, additional, Suzuki, Mitsuko, additional, Fuse, Nozomu, additional, Sato, Akihiro, additional, Ikeno, Takashi, additional, Nomura, Shogo, additional, Bando, Hideaki, additional, Odegaard, Justin Iver, additional, Fujii, Satoshi, additional, Ebi, Hiromichi, additional, Yoshino, Takayuki, additional, and Nakamura, Yoshiaki, additional

Published
2023
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186. Mechanisms of fever-induced QT prolongation and torsades de pointes in patients with KCNH2 mutation

Author

Usuda, Keisuke, primary, Hayashi, Kenshi, additional, Nakajima, Tadashi, additional, Kurata, Yasutaka, additional, Cui, Shihe, additional, Kusayama, Takashi, additional, Tsuda, Toyonobu, additional, Tada, Hayato, additional, Kato, Takeshi, additional, Sakata, Kenji, additional, Usui, Soichiro, additional, Fujino, Noboru, additional, Tanaka, Yoshihiro, additional, Kaneko, Yoshiaki, additional, Kurabayashi, Masahiko, additional, Tange, Shoichi, additional, Saito, Takekatsu, additional, Ohta, Kunio, additional, Yamagishi, Masakazu, additional, and Takamura, Masayuki, additional

Published
2023
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192. Effect of Boron-Doping on Gate-Opening CO2Adsorption in Zinc-Benzimidazolate Coordination Networks

Author

Akiyama, Ikuho, Kato, Takeshi, Kannaka, Shino, Ito, Akitaka, and Ohtani, Masataka

Abstract

Flexible metal–organic frameworks (MOFs) have attracted much attention as selective gas adsorption and storage. This report describes boron doping in zeolitic imidazolate framework-7 (B-ZIF-7), which exhibits reversible phase transition during CO2adsorption/desorption. We have successfully prepared B-ZIF-7 coordination networks using boron-bridged benzimidazolate (B(bim)4–) as organic ligands. Powder X-ray diffraction (PXRD) measurements and infrared spectroscopy revealed that B-ZIF-7 has a crystal structure similar to that of ZIF-7 while containing boron bridging in the coordination network. Since B-ZIF-7 forms a cationic coordination network, the guest anions are encapsulated within the pore. CO2adsorption/desorption measurements at 300 K showed that B-ZIF-7(NO3), which contains nitrate ions (NO3–) as guest anions in its pores, exhibits a S-shaped CO2adsorption/desorption isotherm, which is characteristic of gate-opening type MOFs. Compared with ZIF-7, B-ZIF-7(NO3) has superior CO2adsorption capacity in the low-pressure and superior CO2storage capacity. The CO2adsorption and desorption behavior of B-ZIF-7(NO3) was analyzed by in situtemperature-controlled PXRD measurements and thermogravimetric analysis under a CO2atmosphere, and a reversible phase transition was observed. We have also successfully prepared B-ZIF-7(Cl) and B-ZIF-7(OTf) (OTf = CF3SO3–) with different guest anions. The CO2adsorption/desorption behaviors of B-ZIF-7(Cl) and B-ZIF-7(OTf) were significantly different from those of B-ZIF-7(NO3) and ZIF-7. B-ZIF-7(Cl) showed gate opening at a higher pressure than ZIF-7, and B-ZIF-7(OTf) did not show S-shaped CO2adsorption isotherm and showed adsorption behavior in micropores. These results indicate that the CO2adsorption behavior of B-ZIF-7 depends on the interaction between the guest anions and CO2molecules or the cationic framework and the bulkiness of the guest anions. Boron doping in a coordination network with boron-bridged imidazolate ligands is a promising strategy to increase the gas adsorption capability of porous materials.

Published
2024
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Author

Kato, Takeshi and Kato, Takeshi

Abstract

Reducing wealth inequality and disparity is a global challenge. To accomplish this, the economic systems that produce inequality must be transformed. The economic system is mainly divided into (1) gift and reciprocity, (2) power and redistribution, (3) market exchange, and (4) mutual aid without reciprocal obligations. The current inequality stems from a capitalist economy consisting of (2) and (3). To sublimate (1), which is the human economy, to (4), the concept of a “mixbiotic society” has been proposed in the philosophical realm. This is a society in which free and diverse individuals, “I,” mix with each other, recognize their respective “fundamental incapability” and sublimate them into “WE” solidarity. The economy in this society must have moral responsibility as a coadventurer and consideration for vulnerability to risk. Therefore, I focus on two factors of mind perception: moral responsibility and risk vulnerability, and propose a novel model of wealth distribution between two agents following an econophysical approach. Specifically, I developed a joint-venture model in which profits and losses are distributed based on their own factors; a redistribution model in which wealth stocks are redistributed periodically based on their own factors in the joint-venture model; and a “WE economy” model in which profits and losses are distributed based on the ratio of each other’s factors. A simulation comparison of a combination of the joint ventures and redistribution with the WE economies reveals that WE economies are effective in reducing inequality and resilient in normalizing wealth distribution as advantages, and susceptible to free riders as disadvantages. However, this disadvantage can be compensated for by fostering consensus and fellowship, and by complementing it with joint ventures. Although this study does not reflect the real economy, because it is a basic model, it essentially presents the validity of moral responsibility, the complementarity between the

Published
2023

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Author

Kato, Takeshi and Kato, Takeshi

Abstract

Aiming for a mixbiotic society that combines freedom and solidarity among people with diverse values, we focused on nonviolent communication (NVC) that enables compassionate giving in various situations of social division and conflict, and tried a generative AI for it. Specifically, ChatGPT was used in place of the traditional certified trainer to test the possibility of mediating (modifying) input sentences in four processes: observation, feelings, needs, and requests. The results indicate that there is potential for the application of generative AI, although not yet at a practical level. Suggested improvement guidelines included adding model responses, relearning revised responses, specifying appropriate terminology for each process, and re-asking for required information. The use of generative AI will be useful initially to assist certified trainers, to prepare for and review events and workshops, and in the future to support consensus building and cooperative behavior in digital democracy, platform cooperatives, and cyber-human social co-operating systems. It is hoped that the widespread use of NVC mediation using generative AI will lead to the early realization of a mixbiotic society.

Published
2023

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Author

Kato, Takeshi, Miyakoshi, Jyunichi, Matsumura, Tadayuki, Kudo, Yasuyuki, Mine, Ryuji, Mizuno, Hiroyuki, Deguchi, Yasuo, Kato, Takeshi, Miyakoshi, Jyunichi, Matsumura, Tadayuki, Kudo, Yasuyuki, Mine, Ryuji, Mizuno, Hiroyuki, and Deguchi, Yasuo

Abstract

The philosophical world has proposed the concept of “mixbiotic society, ” in which individuals with freedom and diverse values mix and mingle to recognize their respective “fundamental incapability” each other and sublimate into solidarity, toward solving the issues of social isolation and fragmentation. Based on this concept, the mixbiotic society measures have been proposed to evaluate dynamic communication patterns with reference to classification in cellular automata and particle reaction–diffusion that simulate living phenomena. In this report, we applied these measures to five typologies of organizational structure (Red: impulsive, Amber: adaptive, Orange: achievement, Green: pluralistic, and Teal: evolutionary) and evaluated their features. Specifically, we formed star, tree, tree+jumper, tree+more jumper, and small-world type networks corresponding to each of the five typologies, conducted communication simulations on these networks, and calculated values for the mixbiotic society measures. The results showed that the Teal organization has the highest value of the mixism measure among the mixbiotic society measures, i.e., it balances similarity (mixing) and dissimilarity (mingling) in communication, and is living and mixbiotic between order and chaos. Measures other than mixism showed that in Teal organization, information is not concentrated in the central leader and that communication takes place among various members. This evaluation of organizational structures shows that the mixbiotic society measures is also useful for assessing organizational change. In the future, these measures will be used not only in business organizations, but also in digital democratic organizations and platform cooperatives in conjunction with information technology.

Published
2023

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Author

Kato, Takeshi, Miyakoshi, Jyunichi, Matsumura, Tadayuki, Mine, Ryuji, Mizuno, Hiroyuki, Deguchi, Yasuo, Kato, Takeshi, Miyakoshi, Jyunichi, Matsumura, Tadayuki, Mine, Ryuji, Mizuno, Hiroyuki, and Deguchi, Yasuo

Abstract

Social isolation is caused by the impoverishment of community (atomism) and fragmentation is caused by the enlargement of in-group (mobism), both of which can be viewed as social problems related to communication. To solve these problems, the philosophical world has proposed the concept of “mixbiotic society, ” in which individuals with freedom and diverse values mix and mingle to recognize their respective “fundamental incapability” each other and sublimate into solidarity. Based on this concept, this study proposes new mixbiotic society measures to evaluate dynamic communication patterns, replacing the conventional static social network analysis, with reference to classification in cellular automata and particle reaction–diffusion that simulate living phenomena. Specifically, the hypothesis of measures corresponding to the four classes was formulated, and the hypothesis was validated by simulating the generation and disappearance of communication. As a result, considering communication patterns as multidimensional vectors, it found that the mean of Euclidean distance for “mobism, ” the variance of the relative change in distance for “atomism, ” the composite measure that multiplies the mean and variance of cosine similarity for “mixism, ” which corresponds to the well-going of mixbiotic society, and the almost zero measures for “nihilism, ” are suitable. Then, evaluating seven real-society datasets using these measures, we showed that the mixism measure is useful for assessing the livingness of communication, and that it is possible to typify communities based on plural measures. The measures established in this study are superior to conventional analysis in that they can evaluate dynamic patterns, they are simple to calculate, and their meanings are easy to interpret. As a future development, in conjunction with additional validation with various data sets, the mixbiotic society measures will be used to analyze issues of isolation and fragmentation, as well as in

Published
2023

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