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381 results on '"Keklik, Muzaffer"'

153. Evaluation of the efficacy and safety of original filgrastim (Neupogen®), biosimilar filgrastim (Leucostim®) and Lenograstim (Granocyte®) in CD34+ peripheral hematopoietic stem cell mobilization procedures for allogeneic hematopoietic stem cell transplant donors

Author

Sivgin, Serdar, primary, Karakus, Esen, additional, Keklik, Muzaffer, additional, Zararsiz, Gokmen, additional, Solmaz, Musa, additional, Kaynar, Leylagul, additional, Eser, Bulent, additional, Cetin, Mustafa, additional, and Unal, Ali, additional

Published
2016
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181. An Acute Transverse Myelitis Attack after Total Body Irradiation: A Rare Case

Author

Keklik, Muzaffer, Kaynar, Leylagul, Yildirim, Afra, Sivgin, Serdar, Eroglu, Celalettin, Cingoz, Serife, Pala, Cigdem, Eser, Bulent, Cetin, Mustafa, and Unal, Ali

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Article Subject
Abstract

Total body irradiation (TBI) combined with chemotherapy is widely used as a pretreatment regimen of bone marrow transplantation (BMT) in hematologic disorders. Late complications related to TBI as part of the conditioning regimen for hematopoietic stem cell transplantation have been revealed. Acute transverse myelitis (ATM) is a neurological syndrome characterized by disorder of motor, sensorial, and autonomic nerves, and tracts at medulla spinalis, which is resulted from involvement of spinal cord. In this paper, we presented an ATM attack developed after TBI in a patient with acute lymphoblastic leukemia (ALL) as it is a rarely seen case.

Published
2013
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182. A Case with Niemann-Pick Disease and Concomitant Kartagener’s SyndromeKartagener Sendromu’nun Eşlik Ettiği Bir Niemann-Pick Olgusu

Author

KEKLİK, Muzaffer and ÇETİN, Mustafa

Abstract

Case ReportA Case with Niemann-Pick Disease and Concomitant Kartagener’s SyndromeMuzaffer Keklik1, Serdar Şıvgın1, Süleyman Baldane2, Afra Yıldırım3, Olgun Kontaş4, Fatih Kardaş5, Çiğdem Pala1, Mustafa Çetin1, Ali Ünal11Department of Hematology, Faculty of Medicine, Erciyes University, Kayseri, Turkey 2Department of Internal Medicine, Faculty of Medicine, Erciyes University, Kayseri, Turkey 3Department of Radiology, Faculty of Medicine, Erciyes University, Kayseri, Turkey 4Department of Pathology, Faculty of Medicine, Erciyes University, Kayseri, Turkey 5Department of Pediatric Metabolism and Nutrition, Faculty of Medicine, Erciyes University, Kayseri, Turkey Erciyes Med J 2013; 35: 174-176DOI: 10.5152/etd.2013.29This article was viewed 47 times, downloaded 35 timesKey Words: Bone marrow, Kartagener's Syndrome, Niemann- Pick diseaseFull Text (PDF)Related ArticlesSend a commentShareAbstractNiemann-Pick disease is a rare lipid storage disorder with autosomal recessive inheritance, which is characterised by the accumulation of sphingomyelin and other sphingolipids in macrophages. Kartagener's Syndrome is a syndrome with autosomal recessive inheritance consisting of chronic paranasal sinusitis, situs inversus, and bronchiectasis. Here we reported a case having Kartagener's Syndrome with concomitant Niemann- Pick disease, as such a case has not been reported in the literature.TurkishBaşlık:Kartagener Sendromu’nun Eşlik Ettiği Bir Niemann-Pick OlgusuAnahtar Kelimeler:Kemik iliği, kartagener sendromu, niemannpick hastalığıNiemann-Pick Hastalığı, nadir bir lipid depo hastalığı olup otozomal resesif kalıtılır, makrofajlarda sfingomyelin ve diğer sfingolipidlerin birikimi ile karakterizedir. Kartagener Sendromu, otozomal resesif kalıtılan bir sendrom olup kronik paranazal sinüzit, situs inversus ve bronşiektazi triadını içerir.Bu çalışmada, Niemann-Pick Hastalığı ve Kartagener Sendromu birlikteliği olan bir olguyu, literatürde rastlanmamış olması nedeniyle sunduk.&nbsp

Published
2012

197. Pretransplant elevated serum ferritin levels are associated with increased risk of invasivefungal pneumonia (IFP) in patients that underwent allogeneic hematopoietic stem celltransplantation (alloHSCT)

Author

ÜNAL, Ali, DEMİRASLAN, Hayati, ESER, Bülent, ŞIVGIN, Serdar, PALA, Çiğdem, ÇETİN, Mustafa, KEKLİK, Muzaffer, and KAYNAR, Leylagül

Abstract

Objectives and aim: Invasive fungal pneumonia (IFP) has become increasingly common in patients that previously underwentalloHSCT due to prolonged neutropenia, immunosuppressive therapies to prevent Graft-vs-host disease (GvHD) and widespreaduse of broad-spectrum antibiotics. The aim of this study was to determine the role of hyperferritinemia in invasive fungalpneumonia in patients that underwent alloHSCT.Materials and Methods: Medical records of 73 patients with pneumonia that underwent alloHSCT were studied retrospectively,whereby a pre-transplantation serum ferritin level measured up to 100 days prior to transplantation of patients with invasivefungal pneumonia (IFP) and non-fungal pneumonia (non-IFP) was compared.Results: Patient records revealed 35 and 38 cases of IFP and non-IFP respectively. All 35 patients diagnosed with IFP alsoshowed signs of probable pneumonia. Isolated causative microorganisms were Candida spp in five (14.2 %) of the patients andAspergillosis in three (8.6 %). In risk evaluation for IFP, age, gender, HLA status, conditioning regimen, CD34+ count, donorgender, GVHD presence, smoking history, and underlying disease were not significantly different among groups (p > 0.05).However, performance status (Karnofsky) was significantly lower in patients with IFP (p < 0.05), compared to the control group.The median ferritin levels were 1705 ng/ml (41 − 7198) in the IFP group and 845 ng/ml (18 − 7099) in non-IFP group and thedifference was found statistically significant (p = 0.001).Conclusion: Elevated pretransplant serum ferritin level is associated with IFP in patients that underwent alloHSCT, in particularwhen values exceed 1550 ng/ml.

Published
2012

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