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652 results on '"Kim, Heung Dong"'

152. Review of clinical studies of perampanel in adolescent patients

Author

Kim, Heung Dong, primary, Chi, Ching‐Shiang, additional, Desudchit, Tayard, additional, Nikanorova, Marina, additional, Visudtibhan, Anannit, additional, Nabangchang, Charcrin, additional, Chan, Derrick W. S., additional, Fong, Choong Yi, additional, Chang, Kai‐Ping, additional, Kwan, Shang‐Yeong, additional, Reyes, Fe De Los, additional, Huang, Chao‐Ching, additional, Likasitwattanakul, Surachai, additional, Lee, Wang‐Tso, additional, Yung, Ada, additional, and Dash, Amitabh, additional

Published
2016
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153. Surgical versus medical treatment for children with epileptic encephalopathy in infancy and early childhood: Results of an international multicenter cohort study in Far-East Asia (the FACE study)

Author

Otsuki, Taisuke, primary, Kim, Heung-Dong, additional, Luan, Guoming, additional, Inoue, Yushi, additional, Baba, Hiroshi, additional, Oguni, Hirokazu, additional, Hong, Seung-Chyul, additional, Kameyama, Shigeki, additional, Kobayashi, Katsuhiro, additional, Hirose, Shinichi, additional, Yamamoto, Hitoshi, additional, Hamano, Shin-ichiro, additional, and Sugai, Kenji, additional

Published
2016
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154. Interregional metabolic connectivity of 2‐deoxy‐2[18F]fluoro‐D‐glucose positron emission tomography in vagus nerve stimulation for pediatric patients with epilepsy: A retrospective cross‐sectional study.

Author

Yu, Rita, Park, Hae‐Jeong, Cho, Hojin, Ko, Ara, Pae, Chongwon, Oh, Maeng‐Keun, Kang, Hoon‐Chul, Kim, Heung Dong, Park, Eun‐Kyung, Shim, Kyu‐Won, Kim, Dong Suk, and Lee, Joon Soo

Subjects
CHILDHOOD epilepsy, NEURAL stimulation, GLUCOSE metabolism, POSITRON emission tomography, CEREBELLUM
Abstract

Summary: Objective: With the recognition of epilepsy as a network disease that disrupts the organizing ability of resting‐state brain networks, vagus nerve stimulation (VNS) may control epileptic seizures through modulation of functional connectivity. We evaluated preoperative 2‐deoxy‐2[18F]fluoro‐D‐glucose (FDG) positron emission tomography (PET) in VNS‐implanted pediatric patients with refractory epilepsy to analyze the metabolic connectivity of patients and its prognostic role in seizure control. Methods: Preoperative PET data of 66 VNS pediatric patients who were followed up for a minimum of 1 year after the procedure were collected for the study. Retrospective review of the patients' charts was performed, and five patients with inappropriate PET data or major health issues were excluded. We conducted an independent component analysis of FDG‐PET to extract spatial metabolic components and their activities, which were used to perform cross‐sectional metabolic network analysis. We divided the patients into VNS‐effective and VNS‐ineffective groups (VNS‐effective group, ≥50% seizure reduction; VNS‐ineffective group, <50% reduction) and compared metabolic connectivity differences between groups using a permutation test. Results: Thirty‐four (55.7%) patients showed >50% seizure reduction from baseline frequency 1 year after VNS. A significant difference in metabolic connectivity evaluated by preoperative FDG‐PET was noted between groups. Relative changes in glucose metabolism were strongly connected among the areas of brainstem, cingulate gyrus, cerebellum, bilateral insula, and putamen in patients with <50% seizure control after VNS. Significance: This study shows that seizure outcome of VNS may be influenced by metabolic connectivity, which can be obtained from preoperative PET imaging. This study of metabolic connectivity analysis may contribute in further understanding of the mechanism of VNS in intractable seizures. [ABSTRACT FROM AUTHOR]

Published
2018
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173. Clinical analysis of catastrophic epilepsy in infancy and early childhood: Results of the Far-East Asia Catastrophic Epilepsy (FACE) study group

Author

Oguni, Hirokazu, primary, Otsuki, Taisuke, additional, Kobayashi, Katsuhiro, additional, Inoue, Yushi, additional, Watanabe, Eiji, additional, Sugai, Kenji, additional, Takahashi, Akio, additional, Hirose, Shinichi, additional, Kameyama, Shigeki, additional, Yamamoto, Hitoshi, additional, Hamano, Shinichiro, additional, Baba, Koichi, additional, Baba, Hiroshi, additional, Hong, Seung-Chyul, additional, Kim, Heung-Dong, additional, Kang, Hoon-Chul, additional, Luan, Guoming, additional, and Wong, Tai-Tong, additional

Published
2013
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181. Effects of lamotrigine on cognition and behavior compared to carbamazepine as monotherapy for children with partial epilepsy

Author

Eun, So-Hee, primary, Eun, Baik-Lin, additional, Lee, Joon Soo, additional, Hwang, Yong Seung, additional, Kim, Ki Joong, additional, Lee, Young-Mock, additional, Lee, In Goo, additional, Lee, Munhyang, additional, Ko, Tae-Sung, additional, Kim, Jeong Tae, additional, Eom, Soyong, additional, and Kim, Heung Dong, additional

Published
2012
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186. Genetic and Epileptic Features in Rett Syndrome

Author

Kim, Hyo Jeong, primary, Kim, Shin Hye, additional, Kim, Heung Dong, additional, Lee, Joon Soo, additional, Lee, Young-Mock, additional, Koo, Kyo Yeon, additional, Lee, Jin Sung, additional, and Kang, Hoon-Chul, additional

Published
2012
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