169 results on '"Meunier, Christophe"'
Search Results
152. Biofuel cells Based on the Immobilization of Photosynthetically Active Bioentities
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Meunier, Christophe F., primary, Yang, Xiao-Yu, additional, Rooke, Joanna C., additional, and Su, Bao-Lian, additional
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- 2011
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153. Whole-cell based hybrid materials for green energy production, environmental remediation and smart cell-therapy
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Léonard, Alexandre, primary, Dandoy, Philippe, additional, Danloy, Emeric, additional, Leroux, Grégory, additional, Meunier, Christophe F., additional, Rooke, Joanna C., additional, and Su, Bao-Lian, additional
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- 2011
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154. Novel photosynthetic CO2bioconvertor based on green algae entrapped in low-sodium silica gels
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Rooke, Joanna Claire, primary, Léonard, Alexandre, additional, Sarmento, Hugo, additional, Meunier, Christophe F., additional, Descy, Jean-Pierre, additional, and Su, Bao-Lian, additional
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- 2011
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155. Insight into Cellular Response of Plant Cells Confined within Silica-Based Matrices
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Meunier, Christophe F., primary, Rooke, Joanna C., additional, Hajdu, Kata, additional, Van Cutsem, Pierre, additional, Cambier, Pierre, additional, Léonard, Alexandre, additional, and Su, Bao-Lian, additional
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- 2010
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156. Cyanobacteria immobilised in porous silica gels: exploring biocompatible synthesis routes for the development of photobioreactors
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Léonard, Alexandre, primary, Rooke, Joanna C., additional, Meunier, Christophe F., additional, Sarmento, Hugo, additional, Descy, Jean-Pierre, additional, and Su, Bao-Lian, additional
- Published
- 2010
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157. Living hybrid materials capable of energy conversion and CO2 assimilation
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Meunier, Christophe F., primary, Rooke, Joanna C., additional, Léonard, Alexandre, additional, Xie, Hao, additional, and Su, Bao-Lian, additional
- Published
- 2010
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158. Design of photochemical materials for carbohydrate production via the immobilisation of whole plant cells into a porous silica matrix
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Meunier, Christophe F., primary, Rooke, Joanna C., additional, Léonard, Alexandre, additional, Van Cutsem, Pierre, additional, and Su, Bao-Lian, additional
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- 2010
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159. Investigation of different silica precursors: Design of biocompatible silica gels with long term bio-activity of entrapped thylakoids toward artificial leaf
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Meunier, Christophe F., primary, Cutsem, Pierre Van, additional, Kwon, Young-Uk, additional, and Su, Bao-Lian, additional
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- 2009
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160. Thylakoids entrapped within porous silica gel: towards living matter able to convert energy
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Meunier, Christophe F., primary, Van Cutsem, Pierre, additional, Kwon, Young-Uk, additional, and Su, Bao-Lian, additional
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- 2009
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161. Energy from photobioreactors: Bioencapsulation of photosynthetically active molecules, organelles, and whole cells within biologically inert matrices
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Rooke, Joanna C., primary, Meunier, Christophe, additional, Léonard, Alexandre, additional, and Su, Bao-Lian, additional
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- 2008
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162. Green and sustainable production of high value compounds via a microalgae encapsulation technology that relies on CO2 as a principle reactant.
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Desmet, Jonathan, Meunier, Christophe F., Danloy, Emeric P., Duprez, Marie-Eve, Hantson, Anne-Lise, Thomas, Diane, Cambier, Pierre, Rooke, Joanna C., and Su, Bao-Lian
- Abstract
A very promising and facile one-pot synthesis pathway is presented for the microencapsulation of live cells in a very porous core–shell system based upon a robust matrix. (Alginate–SiO
2 –polycation) shell@(alginate–SiO2 ) core hybrid beads, on the millimeter scale, containing live cells are obtained through cross-linking chemistry and the polycondensation of silicic acid in conjunction with the use of a polycation to negate the surface charge on silica. Very interestingly it is revealed that the polycation used (PDADMAC) plays a very important role in the formation of highly robust core–shell beads. PDADMAC acts as a catalyst in the polycondensation of silicic acid, leading to the formation of a resistant double layer shell comprising of an interior layer of alginate–SiO2 with a very homogeneous distribution of porous SiO2 and an external layer of porous PDADMAC that confines SiO2 within the bead. The photosynthetic chlorophyta Dunaliella tertiolecta, which produces high value metabolites (such as anti-oxidants, pharmacologically active compounds, neutraceuticals etc.) via photosynthesis, has been encapsulated within this core–shell system. Oximetry and fluorescence measurements highlight how this algal culture can remain photosynthetically active over an extraordinarily long period of 13 months for high value compound production, whilst entrapped within a highly porous, mechanically and chemically stable, optically transparent matrix, with no observable leaching of the cells from the core of the beads. HPLC has been employed to highlight the presence of excreted metabolites, based on neutral sugar building blocks such as arabinose, galactose and xylose, in the surrounding media. These results reveal how this kind of high performance, low-cost, and easily scaleable core–shell living material could be employed in large scale photobioreactors (PBRs), to potentially facilitate metabolite harvesting whilst protecting the culture from external contamination and for green energy production and environmental (CO2 ) remediation. [ABSTRACT FROM AUTHOR]- Published
- 2014
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163. Whole-cell based hybrid materials for green energy production, environmental remediation and smart cell-therapy.
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LéonardFRIA Fellow/Chargé de Recherches: Fonds National de la Recherche Scientifique 5 rue d’Egmont B-1000 Bruxelles Belgium., Alexandre, Dandoy, Philippe, Danloy, Emeric, Leroux, Grégory, Meunier, Christophe F., Rooke, Joanna C., and Su, Bao-Lian
- Subjects
ENCAPSULATION (Catalysis) ,PHOTOVOLTAIC cells ,BIOMOLECULES ,CARBON sequestration ,BIOTRANSFORMATION (Metabolism) ,POROSITY - Abstract
This critical review highlights the advances that have been made over recent years in the domain of whole-cell immobilisation and encapsulation for applications relating to the environment and human health, particularly focusing on examples of photosynthetic plant cells, bacteria and algae as well as animal cells. Evidence that encapsulated photosynthetic cells remain active in terms of CO
2 sequestration and biotransformation (solar driven conversion of CO2 into biofuels, drugs, fine chemicals etc.), coupled with the most recent advances made in the field of cell therapy, reveals the need to develop novel devices based on the preservation of living cells within abiotic porous frameworks. This review shall corroborate this statement by selecting precise examples that unambiguously demonstrate the necessity and the benefits of such smart materials. As will be described, the handling and exploitation of photosynthetic cells are enhanced by entrapment or encapsulation since the cells are physically separated from the liquid medium, thereby facilitating the recovery of the metabolites produced. In the case of animal cells, their encapsulation within a matrix is essential in order to create a physical barrier that can protect the cells auto-immune defenders upon implantation into a living body. For these two research axes, the key parameters that have to be kept in mind when designing hybrid materials will be identified, concentrating on essential aspects such as biocompatibility, mechanical strength and controlled porosity (264 references). [ABSTRACT FROM AUTHOR]- Published
- 2011
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164. Whole-cell based hybrid materials for green energy production, environmental remediation and smart cell-therapyPart of the themed issue on hybrid materials.
- Author
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LéonardThese authors contributed equally to this work.FRIA Fellow/Chargé de Recherches: Fonds Nation, Alexandre, Dandoy, Philippe, Danloy, Emeric, Leroux, Grégory, Meunier, Christophe F., Rooke, Joanna C., and Su, Bao-Lian
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SUSTAINABLE chemistry ,ENVIRONMENTAL remediation ,CELLULAR therapy ,MICROENCAPSULATION ,PLANT cells & tissues ,SEQUESTRATION (Chemistry) - Abstract
This critical reviewhighlights the advances that have been made over recent years in the domain of whole-cell immobilisation and encapsulation for applications relating to the environment and human health, particularly focusing on examples of photosynthetic plant cells, bacteria and algae as well as animal cells. Evidence that encapsulated photosynthetic cells remain active in terms of CO2sequestration and biotransformation (solar driven conversion of CO2into biofuels, drugs, fine chemicals etc.), coupled with the most recent advances made in the field of cell therapy, reveals the need to develop novel devices based on the preservation of living cells within abiotic porous frameworks. This review shall corroborate this statement by selecting precise examples that unambiguously demonstrate the necessity and the benefits of such smart materials. As will be described, the handling and exploitation of photosynthetic cells are enhanced by entrapment or encapsulation since the cells are physically separated from the liquid medium, thereby facilitating the recovery of the metabolites produced. In the case of animal cells, their encapsulation within a matrix is essential in order to create a physical barrier that can protect the cells auto-immune defenders upon implantation into a living body. For these two research axes, the key parameters that have to be kept in mind when designing hybrid materials will be identified, concentrating on essential aspects such as biocompatibility, mechanical strength and controlled porosity (264 references). [ABSTRACT FROM AUTHOR]
- Published
- 2011
165. Selective and Reusable lron(II)-Based Molecular Sensor for the Vapor-Phase Detection of Alcohols.
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Naik, Anil D., Robeyns, Koen, Meunier, Christophe F., Léonard, Alexandre F., Rotaru, Aurelian, Tinant, Bernard, Filinchuk, Yaroslav, Bao Lian Su, and Garcia, Yann
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- 2014
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166. Paul à Québec, le génie des lieux comme patrimoine identitaire
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Christophe Meunier, Sylvie Dardaillon, Interactions, transferts, ruptures artistiques et culturels - EA 6301 (InTRu), Université de Tours (UT), Environnement Ville Société (EVS), École normale supérieure - Lyon (ENS Lyon)-École des Mines de Saint-Étienne (Mines Saint-Étienne MSE), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-Université Lumière - Lyon 2 (UL2)-Université Jean Moulin - Lyon 3 (UJML), Université de Lyon-Université de Lyon-Institut National des Sciences Appliquées de Lyon (INSA Lyon), Institut National des Sciences Appliquées (INSA)-Université de Lyon-Institut National des Sciences Appliquées (INSA)-Université Jean Monnet [Saint-Étienne] (UJM)-École Nationale des Travaux Publics de l'État (ENTPE)-École nationale supérieure d'architecture de Lyon (ENSAL)-Centre National de la Recherche Scientifique (CNRS), Pôle de Recherche Francophonies, Interculturel, Communication, Sociolinguistique (PREFICS EA 7469), Université de Bretagne Sud (UBS)-Université de Rennes 2 (UR2), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES), Université de Tours, Institut National des Sciences Appliquées de Lyon (INSA Lyon), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Université de Lyon-Institut National des Sciences Appliquées (INSA)-Centre National de la Recherche Scientifique (CNRS)-École nationale supérieure d'architecture de Lyon (ENSAL)-École des Mines de Saint-Étienne (Mines Saint-Étienne MSE), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-École Nationale des Travaux Publics de l'État (ENTPE)-Université Jean Monnet [Saint-Étienne] (UJM)-Université Jean Moulin - Lyon 3 (UJML), Université de Lyon-Université Lumière - Lyon 2 (UL2)-École normale supérieure - Lyon (ENS Lyon), Environnement, Ville, Société (EVS), École normale supérieure de Lyon (ENS de Lyon)-École des Mines de Saint-Étienne (Mines Saint-Étienne MSE), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Université Jean Monnet - Saint-Étienne (UJM)-École Nationale des Travaux Publics de l'État (ENTPE)-École nationale supérieure d'architecture de Lyon (ENSAL)-Centre National de la Recherche Scientifique (CNRS), Institut National des Sciences Appliquées (INSA)-Université de Lyon-Institut National des Sciences Appliquées (INSA)-Université de Lyon-Centre National de la Recherche Scientifique (CNRS)-École nationale supérieure d'architecture de Lyon (ENSAL)-École des Mines de Saint-Étienne (Mines Saint-Étienne MSE), and MEUNIER, Christophe
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060201 languages & linguistics ,[SHS.LITT]Humanities and Social Sciences/Literature ,bande dessinée ,[SHS.GEO] Humanities and Social Sciences/Geography ,[SHS.INFO]Humanities and Social Sciences/Library and information sciences ,spatialité ,06 humanities and the arts ,General Medicine ,[SHS.GEO]Humanities and Social Sciences/Geography ,060202 literary studies ,[SHS.LITT] Humanities and Social Sciences/Literature ,intericonicité ,lieux ,espace ,espaces ,iconotexte ,0602 languages and literature ,ville ,espace urbain - Abstract
Depuis bientôt quinze ans, le dessinateur québécois Michel Rabagliati fait de sa propre vie le terreau des aventures de Paul, son alter-ego. Paul est un « héros ordinaire ». Sa vie est celle de tout-un-chacun, avec ses joies, ses peines. En 2009, l " auteur remportait le prix du Jury du Festival d " Angoulême avec son album Paul à Québec. Graphic novel de 187 pages, la bande dessinée est centrée sur le beau-père de Paul, Roland Beaulieu. Ce dernier, atteint d " un cancer généralisé, vit une véritable descente aux enfers. Rien n " est épargné aux lecteurs depuis les premiers symptômes jusqu " à la phase terminale. C " est l " occasion pour Rabagliati de rendre hommage à son propre beau-père qu " il avait en admiration. Roland est un Québécois « pure souche », né près des remparts de la « Vieille capitale », un self-made man exemplaire. C " est cet album que nous avons choisi de privilégier, afin d " analyser comment Rabagliati parle, à sa façon, de l " identité québécoise. En 2009, Michel Labrie, dans Le Mouton Noir, journal en ligne québécois, voyait en Paul le témoin d " une « identité québécoise » qu " il définissait de la manière suivante : Paul témoigne de l " identité québécoise. Il la décline par une juste et fine mise en scène des valeurs qui sont les exigences mêmes de notre dignité : l " amour et l " amitié, la famille et le travail.. 1
- Published
- 2016
167. Dynamics of a fluid inside a precessing cylinder
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Lagrange, Romain, Institut de Recherche sur les Phénomènes Hors Equilibre (IRPHE), Centre National de la Recherche Scientifique (CNRS)-Aix Marseille Université (AMU)-École Centrale de Marseille (ECM), Université de Provence - Aix-Marseille I, Patrice Meunier, Christophe Eloy, François Nadal, Aix Marseille Université (AMU)-École Centrale de Marseille (ECM)-Centre National de la Recherche Scientifique (CNRS), Patrice Meunier, Christophe Eloy(meunier@irphe.univ-mrs.fr, eloy@irphe.univ-mrs.fr), Christophe Eloy, François Nadal, and Lagrange, Romain
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[PHYS.PHYS.PHYS-FLU-DYN]Physics [physics]/Physics [physics]/Fluid Dynamics [physics.flu-dyn] ,mode de Kelvin ,Kelvin mode ,[SPI.MECA.MEFL] Engineering Sciences [physics]/Mechanics [physics.med-ph]/Fluids mechanics [physics.class-ph] ,[PHYS.PHYS.PHYS-FLU-DYN] Physics [physics]/Physics [physics]/Fluid Dynamics [physics.flu-dyn] ,[SPI.MECA.MEFL]Engineering Sciences [physics]/Mechanics [physics.med-ph]/Fluids mechanics [physics.class-ph] ,Physics::Fluid Dynamics ,hydrodynamics instability ,transition à la turbulence ,[PHYS.MECA.MEFL] Physics [physics]/Mechanics [physics]/Fluid mechanics [physics.class-ph] ,Écoulement tournant ,[PHYS.MECA.MEFL]Physics [physics]/Mechanics [physics]/Fluid mechanics [physics.class-ph] ,instabilité hydrodynamique ,résonance triadique ,triadic resonance ,Ecoulement tournant ,transition to turbulence ,précession ,Rotating flow - Abstract
This thesis deals with the theoretical and experimental study of the dynamics of a fluid inside a precessing cylinder. It is a rotating flow problem which has many applications in aeronautics (precession of a flying object with a propellant liquid) and in geophysics (influence of the Earth precession on the dynamics of the Earth liquid core). At moderate Reynolds numbers, the precessing flow is the sum of a solid body rotation and waves called Kelvin modes. These waves are resonant when their eigenfrequency equals the precessing frequency. In order to predict the amplitude of a resonant Kelvin mode, a viscous and weakly nonlinear theory has been carried out and confirmed experimentally. When the Reynolds number is increased, the base flow becomes unstable. PIV measurements have shown that this instability is due to an interaction between the Kelvin mode forced by precession and two free Kelvin modes. A linear analysis of stability based on a mechanism of triadic resonance between Kelvin modes predicts correctly the threshold and the growth rate of the instability. This instability is saturated by a geostrophic mode due to the nonlinear and viscous interaction of the free Kelvin modes with themselves. In agreement with experiments, a weakly nonlinear theory shows that the Kelvin modes amplitudes are stationary or oscillating (cycles of intermittency) depending on the Reynolds number. Finally, the fixed point of the nonlinear equations (dynamical system with four degrees of freedom) predicts fairly well the mean flow inside the cylinder, even for very high Reynolds numbers (i.e. Re > 50000)., Cette thèse est une étude théorique et expérimentale de l'écoulement d'un fluide dans un cylindre en précession. Elle s'inscrit dans le domaine des écoulements tournants et trouve de nombreuses applications en aéronautique (précession des objets volants avec carburant liquide) et géophysique (influence de la précession terrestre sur la dynamique du noyau externe). Pour des nombres de Reynolds modérés, l'écoulement d'un fluide en précession est une rotation solide à laquelle se superposent des ondes appelées modes de Kelvin. Ces ondes deviennent résonnantes lorsque leur fréquence propre est égale à la fréquence de précession. Afin de prédire l'amplitude d'un mode de Kelvin résonnant, une théorie visqueuse et faiblement non-linéaire a été développée puis confirmée expérimentalement. Lorsque le nombre de Reynolds augmente, l'écoulement de base devient instable. Des mesures PIV ont montré que cette instabilité est due à une interaction entre le mode forcé par la précession et deux modes de Kelvin libres. Une analyse linéaire de stabilité basée sur un mécanisme de résonance triadique entre modes de Kelvin permet de prédire correctement le seuil et le taux de croissance de l'instabilité. Cette instabilité est saturée par un mode géostrophique créé par l'interaction non-linéaire et visqueuse des modes de Kelvin libres avec eux même. En accord avec les expériences, une théorie faiblement non-linéaire montre que les amplitudes des modes de Kelvin sont stationnaires ou oscillantes (cycles intermittents) en fonction du nombre de Reynolds. Finalement, le point fixe des équations non-linéaires (système dynamique à quatre degrés de liberté) prédit correctement l'écoulement moyen à l'intérieur du cylindre, même pour des très grands nombres de Reynolds (i.e. Re > 50000).
- Published
- 2009
168. Alginate@TiO 2 hybrid microcapsules with high in vivo biocompatibility and stability for cell therapy.
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Leroux G, Neumann M, Meunier CF, Voisin V, Habsch I, Caron N, Michiels C, Wang L, and Su BL
- Subjects
- Animals, Biocompatible Materials, Capsules, Female, Glucuronic Acid, Hexuronic Acids, Rats, Rats, Wistar, Titanium, Alginates, Cell- and Tissue-Based Therapy
- Abstract
Designing new materials to encapsulate living therapeutic cells for the treatment of the diseases caused by protein or hormone deficiencies is a great challenge. The desired materials need to be biocompatible towards both entrapped cells and host organisms, have long-term in vivo stability after implantation, allow the diffusion of nutrients and metabolites, and ensure perfect immune-isolation. The current work investigates the in vivo biocompatibility and stability of alginate@TiO
2 hybrid microcapsules and the immune-isolation of entrapped HepG2 cells, to assess their potential for cell therapy. A comparison was made with alginate-silica hybrid microcapsules (ASA). These two hybrid microcapsules are implanted subcutaneously in female Wistar rats. The inflammatory responses of the rats are monitored by the histological examination of the implants and the surrounding tissues, to indicate their in vivo biocompatibility towards the hosts. The in vivo stability of the microcapsules is evaluated by the recovery rate of the intact microcapsules after implantation. The immune-isolation of the entrapped cells is assessed by their morphology, membrane integrity and intracellular enzymatic activity. The results show high viability of the entrapped cells and insignificant inflammation of the hosts, suggesting the excellent biocompatibility of alginate@TiO2 and ASA microcapsules towards both host organisms and entrapped cells. Compared to the ASA microcapsules, more intact alginate@TiO2 hybrid microcapsules are recovered 2-day and 2-month post-implantation and more cells remain alive, proving their better in vivo biocompability, stability, and immune-isolation. The present study demonstrates that the alginate@TiO2 hybrid microcapsule is a highly promising implantation material for cell therapy., (Copyright © 2021 Elsevier B.V. All rights reserved.)- Published
- 2021
- Full Text
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169. Hybrid Alginate@TiO 2 Porous Microcapsules as a Reservoir of Animal Cells for Cell Therapy.
- Author
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Leroux G, Neumann M, Meunier CF, Fattaccioli A, Michiels C, Arnould T, Wang L, and Su BL
- Subjects
- Alginates chemistry, Capsules chemistry, Cations administration & dosage, Cations chemistry, Cell Survival drug effects, Hep G2 Cells, Humans, Oxygen Consumption drug effects, Polyamines chemistry, Titanium administration & dosage, Titanium chemistry, Alginates pharmacology, Capsules pharmacology, Cell- and Tissue-Based Therapy, Polyamines administration & dosage
- Abstract
The number of patients suffering from diseases linked with hormone deficiency (e.g., type 1 diabetes mellitus) has significantly increased in recent years. As organ transplantation presents its limits, the design of novel robust devices for cell encapsulation is of great interest. The current study reports the design of a novel hybrid alginate microcapsule reinforced by titania via a biocompatible synthesis from an aqueous stable titania precursor (TiBALDH) and a cationic polyamine (PDDAC) under mild conditions. The biocompatibility of this one-pot synthesis was confirmed by evaluation of the cytotoxicity of the precursor, additive, product, and by-product. The morphology, structure, and properties of the obtained hybrid microcapsule were characterized in detail. The microcapsule displayed mesoporous, which was a key parameter to allow the diffusion of nutrients and metabolites and to avoid the entry of immune defenders. The hybrid microcapsule also showed enhanced mechanical stability compared to the pure alginate microcapsule, making it an ideal candidate as a cell reservoir. HepG2 model cells encapsulated in the hybrid microcapsules remained intact for 43 days as highlighted by fluorescent viability probes, their oxygen consumption, and their albumin secretion. The study provides a significant progress in the conception of the robust and biocompatible reservoirs of animal cells for cell therapy.
- Published
- 2018
- Full Text
- View/download PDF
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