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152. Impact of Diabetes Mellitus on Critical Limb Ischemia With Below the Knee Disease: Japan Below-the-Knee Artery Treatment Subanalysis

Author

Suzuki, Kenji, primary, Iida, Osamu, additional, Yamauchi, Yasutaka, additional, Nakano, Masatsugu, additional, Soga, Yoshimitsu, additional, Kawasaki, Daizo, additional, Tazaki, Junichi, additional, Yamaoka, Terutoshi, additional, Suematsu, Nobuhiro, additional, Shintani, Yoshiaki, additional, Miyashita, Yusuke, additional, Inoue, Naoto, additional, and Meguro, Taiichiro, additional

Published
2013
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153. Cilostazol Reduces Angiographic Restenosis After Endovascular Therapy for Femoropopliteal Lesions in the Sufficient Treatment of Peripheral Intervention by Cilostazol Study

Author

Iida, Osamu, primary, Yokoi, Hiroyoshi, additional, Soga, Yoshimitsu, additional, Inoue, Naoto, additional, Suzuki, Kenji, additional, Yokoi, Yoshiaki, additional, Kawasaki, Daizo, additional, Zen, Kan, additional, Urasawa, Kazushi, additional, Shintani, Yoshiaki, additional, Miyamoto, Akira, additional, Hirano, Keisuke, additional, Miyashita, Yusuke, additional, Tsuchiya, Taketsugu, additional, Shinozaki, Norihiko, additional, Nakamura, Masato, additional, Isshiki, Takaaki, additional, Hamasaki, Toshimitsu, additional, and Nanto, Shinsuke, additional

Published
2013
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157. REGULATORY T CELL IS ASSOCIATED WITH LIPID PLAQUE IN CORONARY ARTERY WITH INTRAVASCULAR ULTRASOUND USING TISSUE CHARACTERIZATION

Author

Saigusa, Tatsuya, primary, Kashima, Yuichiro, additional, Izawa, Atsushi, additional, Hioki, Hirofumi, additional, Karube, Keninchi, additional, Yaguchi, Tomonori, additional, Abe, Naoyuki, additional, Miura, Takashi, additional, Ebisawa, Soichiro, additional, Aizawa, Kazunori, additional, Koshikawa, Megumi, additional, Kasai, Hiroki, additional, Tomita, Takeshi, additional, Miyashita, Yusuke, additional, Koyama, Jun, additional, and Ikeda, Uichi, additional

Published
2013
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158. Endovascular Treatment for Infrainguinal Vessels in Patients With Critical Limb Ischemia

Author

Iida, Osamu, primary, Nakamura, Masato, additional, Yamauchi, Yasutaka, additional, Kawasaki, Daizo, additional, Yokoi, Yoshiaki, additional, Yokoi, Hiroyoshi, additional, Soga, Yoshimistu, additional, Zen, Kan, additional, Hirano, Keisuke, additional, Suematsu, Nobuhiro, additional, Inoue, Naoto, additional, Suzuki, Kenji, additional, Shintani, Yoshiaki, additional, Miyashita, Yusuke, additional, Urasawa, Kazushi, additional, Kitano, Ikuro, additional, Yamaoka, Terutoshi, additional, Murakami, Takashi, additional, Uesugi, Michitaka, additional, Tsuchiya, Taketsugu, additional, Shinke, Toshiro, additional, Oba, Yasuhiro, additional, Ohura, Norihiko, additional, Hamasaki, Toshimitsu, additional, and Nanto, Shinsuke, additional

Published
2013
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161. Seasonal Variation in Critical Limb Ischemia Requiring Endovascular Therapy: An Analysis of a Multicenter Database of Japanese Patients with Critical Limb Ischemia Undergoing Endovascular Therapy

Author

Takahara, Mitsuyoshi, primary, Iida, Osamu, additional, Soga, Yoshimitsu, additional, Hirano, Keisuke, additional, Yamaoka, Terutoshi, additional, Kawasaki, Daizo, additional, Suzuki, Kenji, additional, Suematsu, Nobuhiro, additional, Shintani, Yoshiaki, additional, Miyashita, Yusuke, additional, Kaneto, Hideaki, additional, and Shimomura, Iichiro, additional

Published
2013
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162. Impact of deteriorated calcium-phosphate homeostasis on amputation-free survival after endovascular revascularization in patients with critical limb ischemia on hemodialysis.

Author

Hioki, Hirofumi, Miyashita, Yusuke, Shiraki, Tatsuya, Iida, Osamu, Uematsu, Masaaki, Miura, Takashi, Ebisawa, Souichirou, and Ikeda, Uichi

Subjects
*HEMODIALYSIS patients, *REVASCULARIZATION (Surgery), *HOMEOSTASIS, *AMPUTATION, *ATHEROSCLEROSIS
Abstract

Patients on hemodialysis (HD) have abnormalities of calcium-phosphate (CaP) homeostasis and high CaP product contributes to atherosclerosis pathogenesis and adverse events. Patients on HD with critical limb ischemia (CLI) are at risk for major amputation and death because of advanced systemic atherosclerotic disease. The aim of this study was to evaluate the relationship between CaP product and amputation-free survival (AFS) in CLI after endovascular treatment (EVT). We retrospectively analyzed 221 CLI patients on HD. In Kaplan–Meier analysis, AFS was significantly lower in patients with CaP product ⩾55 mg2/dL2 compared to those with CaP product <55 mg2/dL2 (54.3% vs 78.5%, p = 0.002). However, neither serum phosphate nor calcium levels were individually associated with AFS. In multivariate analysis, CaP product ⩾55 mg2/dL2 was an independent predictor for AFS in CLI patients on HD (hazard ratio, 3.03; 95% confidence interval, 1.78–5.15; p-value <0.001). We concluded abnormal CaP homeostasis was associated with lower AFS after EVT in CLI patients on HD, and can serve for their risk stratification. [ABSTRACT FROM AUTHOR]

Published
2016
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163. TCT-166 Association between leg wound site and prognosis of hemodialysis patients with critical limb ischemia after isolated infrapopliteal balloon angioplasty

Author

Nakano, Masatsugu, primary, Hirano, Keisuke, additional, Iida, Osamu, additional, Yamauchi, Yasutaka, additional, Soga, Yoshimitsu, additional, Kawasaki, Daizo, additional, Suzuki, Kenji, additional, Yamaoka, Terutoshi, additional, Tazaki, Junichi, additional, Suematsu, Nobuhiro, additional, Shintani, Yoshiaki, additional, and Miyashita, Yusuke, additional

Published
2012
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164. TCT-175 Optimal Antiplatelet Regimen for Critical Limb Ischemia due to Pure Isolated Infrapopliteal Lesions

Author

Tazaki, Junichi, primary, Hirano, Keisuke, additional, Iida, Osamu, additional, Kawasaki, Daizo, additional, Kimura, Takeshi, additional, Miyashita, Yusuke, additional, Shintani, Yoshiaki, additional, Soga, Yoshimitsu, additional, Suematsu, Nobuhiro, additional, Suzuki, Kenji, additional, Yamaoka, Terutoshi, additional, and Yamauchi, Yasutaka, additional

Published
2012
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166. AS-084 Effect of the Lipid Value in Culprit Lesions on In-Stent Restenosis After Coronary Stent Implantation: An Integrated Bacscatter Intravascular Ultrasound Study

Author

Otagiri>, Kyuhachi, primary, Kumazaki, Setsuo, additional, Miyashita, Yusuke, additional, Aso, Shinichi, additional, Saigusa, Tatsuya, additional, Ebisawa, Soichiro, additional, Yaguchi, Tomonori, additional, Hioki, Hirofumi, additional, Aizawa, Kazunori, additional, Koshikawa, Megumi, additional, Kasai, Hiroki, additional, Izawa, Atsushi, additional, Tomita, Takeshi, additional, Koyama, Jun, additional, and Ikeda, Uichi, additional

Published
2012
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167. THE EFFECT OF STATIN ON PATIENTS WITH AORTO-ILIAC ARTERY DISEASE AFTER PRIMARY STENTING

Author

Tazaki, Junichi, primary, Soga, Yoshimitsu, additional, iida, Osamu, additional, Kawasaki, Daizo, additional, Yasutaka, Yamauchi, additional, Suzuki, Kenji, additional, Keisuke, Hirano, additional, Koshida, Ryoji, additional, Kamoi, Daisuke, additional, Higashitani, Michiaki, additional, Shintani, Yoshiaki, additional, Yamaoka, Terutoshi, additional, Okazaki, Shinya, additional, Suematsu, Nobuhiro, additional, Tsuchiya, Taketsugu, additional, Miyashita, Yusuke, additional, Shinozaki, Norihiko, additional, Takahashi, Hiroki, additional, and Kimura, Takeshi, additional

Published
2012
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171. ENDOVASCULAR THERAPY FOR PATIENTS AGED 80 YEARS OR OLDER WITH AORTO-ILIAC LESION

Author

Okamoto, Shin, primary, iida, Osamu, additional, Dohi, Tomoharu, additional, Uematsu, Masaaki, additional, Soga, Yoshimitsu, additional, Kawasaki, Daizo, additional, Suzuki, Kenji, additional, Tazaki, Junichi, additional, Kamoi, Daisuke, additional, Koshida, Ryoji, additional, Shintani, Yoshiaki, additional, Higashitani, Michiaki, additional, Miyashita, Yusuke, additional, Yamaoka, Terutoshi, additional, and Suematsu, Nobuhiro, additional

Published
2012
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172. Hemodialysis-Induced P-Wave Signal-Averaged Electrocardiogram Alterations Are Indicative of Vulnerability to Atrial Arrhythmias

Author

Shimada, Kentaro, primary, Tomita, Takeshi, additional, Kamijo, Yuji, additional, Higuchi, Makoto, additional, Ito, Kenichi, additional, Koizumi, Yoichi, additional, Yamamoto, Kazuya, additional, Aizawa, Kazunori, additional, Koshikawa, Megumi, additional, Kasai, Hiroki, additional, Izawa, Atsushi, additional, Miyashita, Yusuke, additional, Kumazaki, Setsuo, additional, Koyama, Jun, additional, and Ikeda, Uichi, additional

Published
2012
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176. AS-065 Effects of Dyslipidemia and Diabetes Mellitus on Plaque Characteristics in Target Lesions of Acute Coronary Syndrome and Stable Angina

Author

Otagiri, Kyuhachi, primary, Tsutsui, Hiroshi, additional, Kumazaki, Setsuo, additional, Miyashita, Yusuke, additional, Saigusa, Tatsuya, additional, Kimura, Hikaru, additional, Asoh, Sinichi, additional, Aizawa, Kazunori, additional, Koshikawa, Megumi, additional, Kasai, Hiroki, additional, Izawa, Atsushi, additional, Tomita, Takeshi, additional, Koyama, Jun, additional, and Ikeda, Uichi, additional

Published
2011
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177. AS-115 SYNTAX Scores Correlate with the Calcified Component of Plaques in Patients with Stable Angina

Author

Otagiri, Kyuhachi, primary, Tsutsui, Hiroshi, additional, Kumazaki, Setsuo, additional, Miyashita, Yusuke, additional, Saigusa, Tatsuya, additional, Kimura, Hikaru, additional, Asoh, Shinichi, additional, Aizawa, Kazunori, additional, Koshikawa, Megumi, additional, Kasai, Hiroki, additional, Izawa, Atsushi, additional, Tomita, Takeshi, additional, Koyama, Jun, additional, and Ikeda, Uichi, additional

Published
2011
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178. AS-119 Association Between Abdominal Fat Distribution and Tissue Characteristics of Coronary Plaque: Integrated Backscatter Ultrasound Analysis

Author

Kimura, Hikaru, primary, Otagiri, Kyuhachi, additional, Kumazaki, Setsuo, additional, Miyashita, Yusuke, additional, Saigusa, Tatsuya, additional, Aso, Shinichi, additional, Aizawa, Kazunori, additional, Koshikawa, Megumi, additional, Kasai, Hiroki, additional, Izawa, Atsushi, additional, Tomita, Takeshi, additional, Koyama, Jun, additional, and Ikeda, Uichi, additional

Published
2011
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180. LONGITUDINAL LEFT VENTRICULAR STRAIN IS MORE SENSITIVE THAN MID-WALL SHORTENING FOR DETECTING MYOCARDIAL SYSTOLIC DYSFUNCTION IN PATIENTS WITH LIGHT-CHAIN AMYLOIDOSIS

Author

Koyama, Jun, primary, Minamisawa, Ayako, additional, Motoki, Hirohiko, additional, Aizawa, Kazunori, additional, Koshikawa, Megumi, additional, Kasai, Hiroki, additional, Izawa, Atsushi, additional, Tomita, Takeshi, additional, Miyashita, Yusuke, additional, Kumazaki, Setsuo, additional, and Ikeda, Uichi, additional

Published
2011
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181. Early Intervention With Rosuvastatin Decreases the Lipid Components of the Plaque in Acute Coronary Syndrome - Analysis Using Integrated Backscatter IVUS (ELAN Study) -

Author

Otagiri, Kyuhachi, primary, Tsutsui, Hiroshi, additional, Kumazaki, Setsuo, additional, Miyashita, Yusuke, additional, Aizawa, Kazunori, additional, Koshikawa, Megumi, additional, Kasai, Hiroki, additional, Izawa, Atsushi, additional, Tomita, Takeshi, additional, Koyama, Jun, additional, and Ikeda, Uichi, additional

Published
2011
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185. Spironolactone Improves Glucose and Lipid Metabolism by Ameliorating Hepatic Steatosis and Inflammation and Suppressing Enhanced Gluconeogenesis Induced by High-Fat and High-Fructose Diet

Author

Wada, Tsutomu, primary, Kenmochi, Hiroki, additional, Miyashita, Yusuke, additional, Sasaki, Motohiro, additional, Ojima, Minoru, additional, Sasahara, Masakiyo, additional, Koya, Daisuke, additional, Tsuneki, Hiroshi, additional, and Sasaoka, Toshiyasu, additional

Published
2010
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188. LEFT ATRIAL DYSFUNCTION IN PATIENTS WITH SYSTEMIC AMYLOIDOSIS

Author

Minamisawa, Masatoshi, primary, Koyama, Jun, additional, Motoki, Hirohiko, additional, Takahashi, Ayako, additional, Aizawa, Kazunori, additional, Koshikawa, Megumi, additional, Kasai, Hiroki, additional, Izawa, Atsushi, additional, Tomita, Takeshi, additional, Miyashita, Yusuke, additional, Kumazaki, Setsuo, additional, and Ikeda, Uichi, additional

Published
2010
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197. Late Angiographic Stent Thrombosis After Sirolimus-Eluting Stent Implantation

Author

Takahashi, Saeko, primary, Kaneda, Hideaki, additional, Tanaka, Shinji, additional, Miyashita, Yusuke, additional, Shiono, Takaaki, additional, Taketani, Yoshio, additional, Domae, Hiroshi, additional, Matsumi, Junya, additional, Mizuno, Shingo, additional, Minami, Yoshiyasu, additional, Sugitatsu, Kazuya, additional, and Saito, Shigeru, additional

Published
2007
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198. Prognostic Improvement by Multidisciplinary Therapy in Patients With Critical Limb Ischemia.

Author

Hioki, Hirofumi, Miyashita, Yusuke, Miura, Takashi, Ebisawa, Souichirou, Motoki, Hirohiko, Izawa, Atsushi, Tomita, Takeshi, Koyama, Jun, and Ikeda, Uichi

Subjects
PERIPHERAL vascular disease treatment, C-reactive protein, CHI-squared test, COMBINED modality therapy, CONFIDENCE intervals, HEALTH care teams, LEG, LIMB salvage, MULTIVARIATE analysis, PATIENT education, PERIPHERAL vascular diseases, SURVIVAL analysis (Biometry), T-test (Statistics), WOUND care, RETROSPECTIVE studies, REVASCULARIZATION (Surgery), DATA analysis software, DESCRIPTIVE statistics, PROGNOSIS
Abstract

Although limb salvage rate has improved in critical limb ischemia (CLI), an improvement in CLI prognosis has been scarcely reported. Multidisciplinary therapy (MT) including revascularization, wound bed preparation, treatment of comorbidity, and education of patients with CLI may improve prognosis. The aim of this study was to investigate the effectiveness of MT in prognostic improvement. We retrospectively analyzed 72 patients with CLI and assessed whether MT improved prognosis. The incidence of amputation-free survival (freedom from major amputation [MA] and death) was significantly different between the MT and conventional groups at 2 years (0% vs 33%; P = .024). After multivariate analysis, transfusion (hazard ratio [HR] 5.778; 95% confidence interval [CI], 2.372-14.073; P < .001), multivessel coronary disease (HR 3.353; 95% CI, 1.309-8.590; P = .012), and C-reactive protein >5 mg/dL (HR 3.958; 95% CI, 1.359-11.531; P = .012) were independent predictors for MA or death. We concluded that MT was effective in improved mortality and limb salvage rate. [ABSTRACT FROM AUTHOR]

Published
2015
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199. Electrocardiographic J waves are associated with right ventricular morphology and function: evaluation by cardiac magnetic resonance imaging.

Author

Takeuchi, Takahiro, Tomita, Takeshi, Yoshie, Kouji, Hioki, Hirohumi, Oguchi, Yasutaka, Miura, Takashi, Ebisawa, Souichirou, Motoki, Hirohiko, Okada, Ayako, Aizawa, Kazunori, Izawa, Atsushi, Miyashita, Yusuke, Koyama, Jun, and Ikeda, Uichi

Subjects
CARDIOMYOPATHIES, ARRHYTHMOGENIC right ventricular dysplasia, ELECTROCARDIOGRAPHY, RIGHT heart ventricle, ATRIAL fibrillation, MAGNETIC resonance imaging, DIAGNOSIS
Abstract

We assessed the relationship between J waves and the ventricular morphology and function using cardiac magnetic resonance imaging (MRI). The 12-lead electrocardiograms (ECGs) of 105 consecutive patients who underwent cardiac MRI were reviewed, and those with signs of arrhythmogenic right ventricular cardiomyopathy, complete left bundle branch block, complete right bundle branch block, or chronic atrial fibrillation, where the J wave is difficult to distinguish, were excluded. The ECGs of the remaining 68 patients were analyzed for the presence of J waves. Ventricular morphologic abnormalities were identified on MRI, based on the largest short-axis diameter in the right and left ventricles ( d-RV/ d-LV), the area ( a-RV/ a-LV), and the ratio RV/LV. The percentage contraction of the RV (PC-RV) was used as a measure of ventricular function. Thirty-two patients (47.0 %) had J waves defined as QRS-ST junction elevation >0.1 mV from baseline in the inferior/lateral leads (J group; 56 ± 15 years; 19 males). Thirty-six patients (53.0 %) did not present J waves (NJ group; 58 ± 15 years; 27 males). The d-RV and a-RV in the J group were larger than those in the NJ group (41 ± 5.2 vs 36 ± 6.6 mm, P = 0.002 and 14 ± 2.9 vs 12 ± 3.4 cm, P = 0.022, respectively). The RV/LV ratio in the J group was larger than that in the NJ group (0.83 ± 0.15 vs 0.68 ± 0.15, P < 0.001). The PC-RV in the J group was smaller than that in the NJ group (0.28 ± 0.14 vs 0.36 ± 0.15, P = 0.013). J-wave amplitude was correlated positively with d-RV ( P = 0.010) and negatively with PC-RV ( P = 0.005). These results suggested that J waves are associated with right ventricular morphologic and functional abnormalities. [ABSTRACT FROM AUTHOR]

Published
2015
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200. Two-Year Life Expectancy in Patients With Critical Limb Ischemia.

Author

Soga, Yoshimitsu, Iida, Osamu, Takahaera, Mitsuyoshi, Hirano, Keisuke, Suzuki, Kenji, Kawasaki, Daizo, Miyashita, Yusuke, and Tsuchiya, Taketsugu

Abstract

Objectives This study sought to estimate the 2-year life expectancy (2YLE) (estimated survival rate >50% at 2 years) in patients with critical limb ischemia (CLI) using the risk score based on predictors of all-cause mortality within 2 years. Background It has been reported that 2YLE is one of the important factors in the decision making of the revascularization strategy. However, little is known about the probability and the prognostic factors of a 2YLE. Method This study was performed as a multicenter retrospective analysis. Between March 2004 and December 2011, 995 CLI patients with follow-up period >730 days undergoing endovascular therapy (EVT) were identified and analyzed. Results Within 2 years, 412 patients (41%) died, and a cardiovascular cause accounted for 47% of deaths. On multivariate analysis, the independent prognostic factors were age 65 to 79 years (odds ratio [OR]: 1.9), 80 years of age or older (OR: 3.7), body mass index (BMI) 18.0 to 19.9 kg/m 2 (OR: 1.5), BMI <18.0 kg/m 2 (OR: 2.9), nonambulatory status (OR: 2.4), hemodialysis (OR: 2.1), cerebrovascular disease (OR: 1.6), left ventricular ejection fraction (LVEF) of 40% to 49% (OR: 1.8), LVEF <40% (OR: 2.6), Rutherford class 5 (OR: 1.9), and Rutherford class 6 (OR: 3.4). The 2-year survival rate in each risk score was calculated based on each OR (full score: 15 points). After that, 2YLE was estimated based on the survival rate in each risk score, the probability of a 2YLE of ≥8 points indicated a <50% probability of 2-year survival. Conclusions The independent prognostic factors for the 2YLE were age, BMI, nonambulatory status, hemodialysis, cerebrovascular disease, LVEF, and tissue loss. A 2YLE score of ≥8 points indicated a <50% probability of 2-year survival. This score seemed to be helpful for identifying CLI patients with a poor prognosis. [ABSTRACT FROM AUTHOR]

Published
2014
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