5,342 results on '"Perry, John"'
Search Results
152. Comparison of the RGM medium and the mycobacterial growth indicator tube automated system for isolation of non-tuberculous mycobacteria from sputum samples of cystic fibrosis patients in Belgium
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Scohy, Anaïs, Gohy, Sophie, Mathys, Vanessa, Sapriel, Guillaume, Toussaint, Laëtitia, Bressant, Florian, Zitouni, Ali, Teylaert, Marie-Noël, Vander Meeren, Marie-Christine, Colmant, Alexandre, Simon, Anne, Perry, John D., Lebecque, Patrick, and André, Emmanuel
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- 2018
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153. Demonstration of In Vitro Host-Guest Complex Formation and Safety of para-Sulfonatocalix[8]arene as a Delivery Vehicle for Two Antibiotic Drugs
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Moussa, Yvonne E., Ong, Yu Qing Elysia, Perry, John D., Cheng, Zhengqi, Kayser, Veysel, Cruz, Esteban, Kim, Ryung Rae, Sciortino, Natasha, and Wheate, Nial J.
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- 2018
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154. Rare variants in PPARG with decreased activity in adipocyte differentiation are associated with increased risk of type 2 diabetes
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Majithia, Amit R, Flannick, Jason, Shahinian, Peter, Guo, Michael, Bray, Mark-Anthony, Fontanillas, Pierre, Gabriel, Stacey B, Rosen, Evan D, Altshuler, David, Manning, Alisa K, Hartl, Christopher, Agarwala, Vineeta, Green, Todd, Banks, Eric, DePristo, Mark, Poplin, Ryan, Shakir, Khalid, Fennell, Timothy, Njølstad, Pål R, Burtt, Noël, Gabriel, Stacey, Fuchsberger, Christian, Kang, Hun Min, Sim, Xueling, Ma, Clement, Locke, Adam, Blackwell, Thomas, Jackson, Anne, Teslovich, Tanya M, Stringham, Heather, Chines, Peter, Kwan, Phoenix, Huyghe, Jeroen, Tan, Adrian, Jun, Goo, Stitzel, Michael, Bergman, Richard N, Bonnycastle, Lori, Tuomilehto, Jaakko, Collins, Francis S, Scott, Laura, Mohlke, Karen, Abecasis, Gonçalo, Boehnke, Michael, Strom, Tim, Gieger, Christian, Nurasyid, Martina Müller, Grallert, Harald, Kriebel, Jennifer, Ried, Janina, de Angelis, Martin Hrabé, Huth, Cornelia, Meisinger, Christa, Peters, Annette, Rathmann, Wolfgang, Strauch, Konstantin, Meitinger, Thomas, Kravic, Jasmina, Algren, Peter, Ladenvall, Claes, Toumi, Tiinamaija, Isomaa, Bo, Groop, Leif, Gaulton, Kyle, Moutsianas, Loukas, Rivas, Manny, Pearson, Richard, Mahajan, Anubha, Prokopenko, Inga, Kumar, Ashish, Perry, John, Howie, Bryan, van de Bunt, Martijn, Small, Kerrin, Lindgren, Cecilia, Lunter, Gerton, Robertson, Neil, Rayner, William, Morris, Andrew, Buck, David, Hattersley, Andrew, Spector, Tim, McVean, Gil, Frayling, Tim, Donnelly, Peter, McCarthy, Mark, Gupta, Namrata, Taylor, Herman, Fox, Ervin, Cheh, Christopher Newton, Wilson, James G, O'Donnell, Christopher J, Kathiresan, Sekar, Hirschhorn, Joel, Seidman, JG, and Seidman, Christine
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Genetics ,Biotechnology ,Human Genome ,Diabetes ,Aetiology ,2.1 Biological and endogenous factors ,Metabolic and endocrine ,Adipocytes ,Adult ,Aged ,Aged ,80 and over ,Case-Control Studies ,Cell Differentiation ,Diabetes Mellitus ,Type 2 ,Ethnicity ,Female ,Genetic Predisposition to Disease ,Humans ,Male ,Middle Aged ,PPAR gamma ,Polymorphism ,Single Nucleotide ,Risk Factors ,Sequence Analysis ,DNA ,GoT2D Consortium ,NHGRI JHS/FHS Allelic Spectrum Project ,SIGMA T2D Consortium ,T2D-GENES Consortium - Abstract
Peroxisome proliferator-activated receptor gamma (PPARG) is a master transcriptional regulator of adipocyte differentiation and a canonical target of antidiabetic thiazolidinedione medications. In rare families, loss-of-function (LOF) mutations in PPARG are known to cosegregate with lipodystrophy and insulin resistance; in the general population, the common P12A variant is associated with a decreased risk of type 2 diabetes (T2D). Whether and how rare variants in PPARG and defects in adipocyte differentiation influence risk of T2D in the general population remains undetermined. By sequencing PPARG in 19,752 T2D cases and controls drawn from multiple studies and ethnic groups, we identified 49 previously unidentified, nonsynonymous PPARG variants (MAF < 0.5%). Considered in aggregate (with or without computational prediction of functional consequence), these rare variants showed no association with T2D (OR = 1.35; P = 0.17). The function of the 49 variants was experimentally tested in a novel high-throughput human adipocyte differentiation assay, and nine were found to have reduced activity in the assay. Carrying any of these nine LOF variants was associated with a substantial increase in risk of T2D (OR = 7.22; P = 0.005). The combination of large-scale DNA sequencing and functional testing in the laboratory reveals that approximately 1 in 1,000 individuals carries a variant in PPARG that reduces function in a human adipocyte differentiation assay and is associated with a substantial risk of T2D.
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- 2014
155. Use of exogenous volatile organic compounds to detect Salmonella in milk
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Bahroun, Najat H.O., Perry, John D., Stanforth, Stephen P., and Dean, John R.
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- 2018
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156. The Use of CHROMID ® Colistin R for the Detection of Colistin-Resistant Gram-Negative Bacteria in Positive Blood Cultures.
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Marrs, Emma C. L., Milburn, Olivia, Eltringham, Gary J., Fenwick, Danielle J. C., Orenga, Sylvain, Hazırolan, Gulsen, Zarakolu, Pinar, and Perry, John D.
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GRAM-negative bacteria ,COLISTIN ,KLEBSIELLA pneumoniae ,PSEUDOMONAS aeruginosa ,PATHOLOGICAL laboratories - Abstract
The aim of this study was to assess the utility of CHROMID
® Colistin R for direct detection of colistin-resistant Gram-negative bacteria from positive blood cultures. A total of 390 blood cultures from hospitalised patients containing Gram-negative bacteria were included in this study. These blood cultures were referred to clinical laboratories in the United Kingdom and Türkiye. A further 16 simulated positive blood culture bottles were included that contained a range of colistin-resistant strains as well as susceptible control strains. Fluid from each positive blood culture was diluted 1/200 in saline and 10 µL aliquots cultured onto cystine-lactose-electrolyte-deficient agar and CHROMID® Colistin R. All recovered bacteria were identified, and for Gram-negative bacteria, their minimum inhibitory concentration of colistin was measured using the broth microdilution method. From a total of 443 Gram-negative isolates, 57 colistin-resistant isolates were recovered, of which 53 (93%) grew on CHROMID® Colistin R within 18 h. Of the 377 isolates determined to be colistin-susceptible, only 9 isolates were able to grow, including 6 isolates of Pseudomonas aeruginosa. For positive blood cultures that are shown to contain Gram-negative bacteria, culture on CHROMID® Colistin R is a useful diagnostic tool to detect susceptibility or resistance to colistin within 18 h. [ABSTRACT FROM AUTHOR]- Published
- 2024
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157. QSOX2 Deficiency-induced short stature, gastrointestinal dysmotility and immune dysfunction
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Storr, Helen, primary, Maharaj, Avinaash, additional, Andrews, Afiya, additional, Rybak, Anna, additional, Elfeky, Reem, additional, Ishida, Miho, additional, Joensuu, Anni, additional, Kantojärvi, Katri, additional, Jia, Raina, additional, Perry, John, additional, O'Toole, Edel, additional, and Hwa, Vivian, additional
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- 2023
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158. Human HYPOMAP: A comprehensive spatio-cellular map of the human hypothalamus
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Tadross, John A, primary, Steuernagal, Lukas, additional, Dowsett, Georgina, additional, Kentistou, Katherine A, additional, Lundh, Sofia, additional, Porniece, Marta, additional, Klemm, Paul, additional, Rainbow, Kara, additional, Hvid, Henning, additional, Kania, Katarzyna, additional, Polex-Wolf, Joseph, additional, Knudsen, Lotte Bjerre, additional, Pyke, Charles, additional, Perry, John, additional, Lam, Brian Y, additional, Bruening, Jens Claus, additional, and Yeo, Giles S. H., additional
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- 2023
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159. Competition Anxiety in Combat Sports and the Importance of Mental Toughness
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Mojtahedi, Dara, primary, Dagnall, Neil, additional, Denovan, Andrew, additional, Clough, Peter, additional, Dewhurst, Stephen, additional, Hillier, Matthew, additional, Papageorgiou, Kostas, additional, and Perry, John, additional
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- 2023
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160. Profiling human hypothalamic neurons reveals a candidate combination drug therapy for weight loss
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Chen, Hsiao-Jou Cortina, primary, Yang, Andrian, additional, Mazzaferro, Simone, additional, Mali, Iman, additional, Cahn, Olivier, additional, Kentistou, Katherine, additional, Rowley, Christine, additional, Stewart, Natasha, additional, Seah, Jun Wen Eugene, additional, Pisupati, Venkat, additional, Kirwan, Peter, additional, Aggarwal, Sanya, additional, Toyohara, Takafumi, additional, Florido, Mary H C, additional, Cowan, Chad A, additional, Quambusch, Lena, additional, Hyvonen, Marko, additional, Livesey, Matthew R, additional, Perry, John R B, additional, Marioni, John C, additional, and Merkle, Florian T, additional
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- 2023
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161. Bacterial contamination of endoscopist and assistant face visors during gastrointestinal endoscopy: a pilot study
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Nylander, David, primary, Leeds, John, additional, Perry, John, additional, Narayanan, Manjusha, additional, Dipper, Chris, additional, Gunn, Mel, additional, Nayar, Manu, additional, Speight, Ally, additional, and Oppong, Kofi W, additional
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- 2023
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162. U.S. Merchant Marine and our national defense
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Perry, John W.
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MERCHANT MARINE - United States - Abstract
bibliog
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- 1989
163. White lightning in Rotorua
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Perry, John F
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- 1989
164. Moko : the art of the Māori tattoo
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Perry, John
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- 1983
165. Reviews
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Perry, John F
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- 1987
166. Singular Thoughts
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Perry, John, primary
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- 2020
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167. Integrating Frege’s Theories
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Perry, John, primary
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- 2019
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168. Frege's Detour
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Perry, John, primary
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- 2019
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169. Introduction
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Perry, John, primary
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- 2019
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170. “On Sense and Denotation”
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Perry, John, primary
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- 2019
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171. Disarming the Slingshot
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Perry, John, primary
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- 2019
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172. Sense and Denotation: The Theory
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Perry, John, primary
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- 2019
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173. Conclusion
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Perry, John, primary
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- 2019
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174. Episodes and Attitudes
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Perry, John, primary
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- 2019
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175. Frege’s Begriffsschrift: Problems
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Perry, John, primary
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- 2019
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176. Solving the Identity Problems
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Perry, John, primary
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- 2019
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177. Frege’s Begriffsschrift: Accomplishments
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Perry, John, primary
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- 2019
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178. Should ice be cubed?
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Moyer, Richard H., Everett, Susan A., and Perry, John
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- 2012
179. The auditioning academic from industry to academic professional : stories of the journey
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Perry, John E., Garland, Paul, and Close, Paul
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378.1 - Abstract
The purpose of this study was to investigate the professional journey from industry practitioner to higher education academic. The research 'mapped' ten new academics' engagement within the institutional and subject team community throughout their first full teaching year within a higher education institute. A comprehensive literature review was undertaken which initially drew on several theoretical perspectives, such as transitions and socialisation, communities of practice and identity formation. These theoretical positions originated from a mini-focus group. The coding from this initial study together with the reflective thoughts of my own first year in academia led me to read certain topic areas. The literature was further developed throughout the course of the study with the data challenging some of the notions that arose from the initial literature sources. Subsequently new literature was identified which supported the data analysis and emergent themes. The study focussed on the lived experiences of new academics through the use of a narrative methodology which acknowledged that lived experiences are socially constructed. Ten new academics were interviewed at four key stages throughout their first full teaching year. The interviews were transcribed and coded, which led to the development of emergent themes. The key themes were scrutinised through writing narrative chronologies for each of the academics. The narrative chronologies laid the foundation for the development of the conceptual model and research findings. From the research findings a new academic progresses through what can be described as three key overlapping phases (The Reciprocal Phase; The Fragile Phase and The Engaged Phase) within the academic milieu. Within these phases the new academic is seeking to establish identity and legitimacy within the boundaries of the academic communities to which they initially belong. Fundamental throughout these phases is the relationship the new academic has with established academics, who act as gatekeepers to academic practice and communities. The research also finds that institutional policies and practices for new academic entry are found to be inadequate and in light of these key findings a number of changes in professional practice are proposed.
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- 2012
180. Further evidence for the domain specificity of Consideration of Future Consequences in adolescents and University students
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McKay, Michael T., Perry, John L., and Cole, Jon C.
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- 2018
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181. Rapid detection of hydrogen sulfide produced by pathogenic bacteria in focused growth media using SHS-MCC-GC-IMS
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Thompson, Ryan, Perry, John D., Stanforth, Stephen P., and Dean, John R.
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- 2018
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182. Thinking Aloud: An exploration of cognitions in professional snooker
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Welsh, James C., Dewhurst, Stephen A., and Perry, John L.
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- 2018
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183. Wolfe, Montcalm, and the Principles of Joint Operations in the Quebec Campaign of 1759
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Finnan, Joseph, Gray, Lee P., Perry, John H., and Lust, Brian
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French and Indian War, 1754-1763 -- Military aspects -- Analysis ,Quebec Campaign, 1759 -- Military aspects -- Analysis ,Canadian native peoples -- Military aspects -- Analysis ,United States history -- French and Indian War, 1755-1763 ,Military and naval science - Abstract
A critical campaign analysis of the French and Indian War's 1759 Quebec campaign demonstrates that Britain achieved victory because it reflected the principles of joint operations better than its French [...]
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- 2019
184. Mental Toughness and Transitions to High School and to Undergraduate Study
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St Clair-Thompson, Helen, Giles, Rebecca, McGeown, Sarah P., Putwain, David, Clough, Peter, and Perry, John
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Mental toughness can be conceptualised as a set of attributes that allow people to deal effectively with challenges, stressors and pressure. Recent work has suggested that it may be a valuable construct to consider within educational settings. The current studies explored the associations between mental toughness and educational transitions. Study 1 examined the relationships between mental toughness and concerns about moving to a new school in 105 children aged 12-13 years of age. The results revealed significant relationships between several aspects of mental toughness, but particularly confidence in abilities, and children's concerns. Study 2 examined the relationships between mental toughness and adjustment to university in 200 undergraduate students at various stages of their course. The results revealed a role for several aspects of mental toughness; commitment, control of life, control of emotion, confidence in abilities and interpersonal confidence. The results are discussed in terms of implications for educational practice. It is suggested that measures of mental toughness could be used to identify individuals who may benefit from additional support during transition to a new school or to university, and that future research should explore the potential benefits of mental toughness training.
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- 2017
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185. ATM Technology Adoption in U.S. Campus Networking.
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Yao, Engui, Perry, John F., Anderson, Larry S., Brook, R. Dan, Hare, R. Dwight, Moore, Arnold J., and Xu, Xiaohe
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This study examined the relationships between ATM (asynchronous transfer mode) adoption in universities and four organizational variables: university size, type, finances, and information processing maturity. Another purpose of the study was to identify the current status of ATM adoption in campus networking. Subjects were university domain LAN (local area network) administrators in the United States. A questionnaire was posted on the World Wide Web, and Internet e-mail was used to distribute the cover letter. A total of 199 usable responses were received. Logistic regression was used to study the relationship between the variables and ATM adoption, and nested models and an enrollment size model were designed for analyzing data. Results indicated that ATM adoption in campus networking is significantly related to the selected organizational variables. Tables present data on: frequencies for ATM adoption status; descriptive statistics for the predictor variables and categorical variables; and logistic regression coefficients and goodness-of-fit for the nested models and for the enrollment size model. (DLS)
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- 1998
186. A genome-wide association study of early menopause and the combined impact of identified variants
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Perry, John RB, Corre, Tanguy, Esko, Tõnu, Chasman, Daniel I, Fischer, Krista, Franceschini, Nora, He, Chunyan, Kutalik, Zoltan, Mangino, Massimo, Rose, Lynda M, Smith, Albert Vernon, Stolk, Lisette, Sulem, Patrick, Weedon, Michael N, Zhuang, Wei V, Arnold, Alice, Ashworth, Alan, Bergmann, Sven, Buring, Julie E, Burri, Andrea, Chen, Constance, Cornelis, Marilyn C, Couper, David J, Goodarzi, Mark O, Gudnason, Vilmundur, Harris, Tamara, Hofman, Albert, Jones, Michael, Kraft, Peter, Launer, Lenore, Laven, Joop SE, Li, Guo, McKnight, Barbara, Masciullo, Corrado, Milani, Lili, Orr, Nicholas, Psaty, Bruce M, Ridker, Paul M, Rivadeneira, Fernando, Sala, Cinzia, Salumets, Andres, Schoemaker, Minouk, Traglia, Michela, Waeber, Gérard, Chanock, Stephen J, Demerath, Ellen W, Garcia, Melissa, Hankinson, Susan E, Hu, Frank B, Hunter, David J, Lunetta, Kathryn L, Metspalu, Andres, Montgomery, Grant W, Murabito, Joanne M, Newman, Anne B, Ong, Ken K, Spector, Tim D, Stefansson, Kari, Swerdlow, Anthony J, Thorsteinsdottir, Unnur, Van Dam, Rob M, Uitterlinden, André G, Visser, Jenny A, Vollenweider, Peter, Toniolo, Daniela, and Murray, Anna
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Biotechnology ,Contraception/Reproduction ,Infertility ,Genetics ,Human Genome ,Aging ,Estrogen ,Prevention ,Aetiology ,2.1 Biological and endogenous factors ,Reproductive health and childbirth ,Good Health and Well Being ,Case-Control Studies ,Female ,Gene Frequency ,Genome-Wide Association Study ,Humans ,Menopause ,Premature ,Polymorphism ,Single Nucleotide ,Primary Ovarian Insufficiency ,Quantitative Trait Loci ,Risk ,ReproGen Consortium ,Biological Sciences ,Medical and Health Sciences ,Genetics & Heredity - Abstract
Early menopause (EM) affects up to 10% of the female population, reducing reproductive lifespan considerably. Currently, it constitutes the leading cause of infertility in the western world, affecting mainly those women who postpone their first pregnancy beyond the age of 30 years. The genetic aetiology of EM is largely unknown in the majority of cases. We have undertaken a meta-analysis of genome-wide association studies (GWASs) in 3493 EM cases and 13 598 controls from 10 independent studies. No novel genetic variants were discovered, but the 17 variants previously associated with normal age at natural menopause as a quantitative trait (QT) were also associated with EM and primary ovarian insufficiency (POI). Thus, EM has a genetic aetiology which overlaps variation in normal age at menopause and is at least partly explained by the additive effects of the same polygenic variants. The combined effect of the common variants captured by the single nucleotide polymorphism arrays was estimated to account for ∼30% of the variance in EM. The association between the combined 17 variants and the risk of EM was greater than the best validated non-genetic risk factor, smoking.
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- 2013
187. Migrant Education: Thirty Years of Success, but Challenges Remain.
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New England Desegregation Assistance Center, Providence, RI., Brown Univ., Providence, RI. Education Alliance for Equity in the Nation's Schools., and Perry, John D.
- Abstract
Despite over 30 years of work by the Migrant Education Program (MEP), rural migrant students may still be the most disadvantaged student population in the nation. Migrant youth problems include constant adjustment to a new environment, cultural differences, and lack of language skills. In defining these problems, this report looks at a typical school, the demography of migrant workers, the needs of migrant students (educational, behavioral, eligibility for federal programs), and school completion rates. A brief history is given of the authorization and structure of the MEP, as well as a description of its services: identification and recruitment, support services, home-school liaison, health services, parental involvement, summer programs, early childhood services, credit accrual and alternative programs for secondary students, college assistance, and student records technology. A case is made for use of the MEP as a model to achieve equity in urban districts. Relevant elements include understanding the customers, training staff to have high expectations, contacting families each year, providing brokerage services to families, developing coordinated early childhood services, using the Even Start model, advocating within the school, tracking student mobility, using flexible scheduling, providing summer school, retrieving students, and involving parents. The goals of the Improving America's Schools Act (IASA) are discussed in reference to serving migrant students and coordinating MEP and Title I services and funding. Challenges for the future are outlined: conflicts associated with IASA and Title I; anti-immigrant attitudes; funding problems; coordination at national, state, and local levels; involvement of employers and state governments; and political advocacy. (SAS)
- Published
- 1997
188. Using Genome Wide Association Studies to Understand the Aetiolog of Type 2 Diabetes
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Perry, John Richard Bradbury
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616.042 - Published
- 2010
189. Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution
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Justice, Anne E., Karaderi, Tugce, Highland, Heather M., Young, Kristin L., Graff, Mariaelisa, Lu, Yingchang, Turcot, Valérie, Auer, Paul L., Fine, Rebecca S., Guo, Xiuqing, Schurmann, Claudia, Lempradl, Adelheid, Marouli, Eirini, Mahajan, Anubha, Winkler, Thomas W., Locke, Adam E., Medina-Gomez, Carolina, Esko, Tõnu, Vedantam, Sailaja, Giri, Ayush, Lo, Ken Sin, Alfred, Tamuno, Mudgal, Poorva, Ng, Maggie C. Y., Heard-Costa, Nancy L., Feitosa, Mary F., Manning, Alisa K., Willems, Sara M., Sivapalaratnam, Suthesh, Abecasis, Goncalo, Alam, Dewan S., Allison, Matthew, Amouyel, Philippe, Arzumanyan, Zorayr, Balkau, Beverley, Bastarache, Lisa, Bergmann, Sven, Bielak, Lawrence F., Blüher, Matthias, Boehnke, Michael, Boeing, Heiner, Boerwinkle, Eric, Böger, Carsten A., Bork-Jensen, Jette, Bottinger, Erwin P., Bowden, Donald W., Brandslund, Ivan, Broer, Linda, Burt, Amber A., Butterworth, Adam S., Caulfield, Mark J., Cesana, Giancarlo, Chambers, John C., Chasman, Daniel I., Chen, Yii-Der Ida, Chowdhury, Rajiv, Christensen, Cramer, Chu, Audrey Y., Collins, Francis S., Cook, James P., Cox, Amanda J., Crosslin, David S., Danesh, John, de Bakker, Paul I. W., Denus, Simon de, Mutsert, Renée de, Dedoussis, George, Demerath, Ellen W., Dennis, Joe G., Denny, Josh C., Di Angelantonio, Emanuele, Dörr, Marcus, Drenos, Fotios, Dubé, Marie-Pierre, Dunning, Alison M., Easton, Douglas F., Elliott, Paul, Evangelou, Evangelos, Farmaki, Aliki-Eleni, Feng, Shuang, Ferrannini, Ele, Ferrieres, Jean, Florez, Jose C., Fornage, Myriam, Fox, Caroline S., Franks, Paul W., Friedrich, Nele, Gan, Wei, Gandin, Ilaria, Gasparini, Paolo, Giedraitis, Vilmantas, Girotto, Giorgia, Gorski, Mathias, Grallert, Harald, Grarup, Niels, Grove, Megan L., Gustafsson, Stefan, Haessler, Jeff, Hansen, Torben, Hattersley, Andrew T., Hayward, Caroline, Heid, Iris M., Holmen, Oddgeir L., Hovingh, G. Kees, Howson, Joanna M. M., Hu, Yao, Hung, Yi-Jen, Hveem, Kristian, Ikram, M. Arfan, Ingelsson, Erik, Jackson, Anne U., Jarvik, Gail P., Jia, Yucheng, Jørgensen, Torben, Jousilahti, Pekka, Justesen, Johanne M., Kahali, Bratati, Karaleftheri, Maria, Kardia, Sharon L. R., Karpe, Fredrik, Kee, Frank, Kitajima, Hidetoshi, Komulainen, Pirjo, Kooner, Jaspal S., Kovacs, Peter, Krämer, Bernhard K., Kuulasmaa, Kari, Kuusisto, Johanna, Laakso, Markku, Lakka, Timo A., Lamparter, David, Lange, Leslie A., Langenberg, Claudia, Larson, Eric B., Lee, Nanette R., Lee, Wen-Jane, Lehtimäki, Terho, Lewis, Cora E., Li, Huaixing, Li, Jin, Li-Gao, Ruifang, Lin, Li-An, Lin, Xu, Lind, Lars, Lindström, Jaana, Linneberg, Allan, Liu, Ching-Ti, Liu, Dajiang J., Luan, Jian’an, Lyytikäinen, Leo-Pekka, MacGregor, Stuart, Mägi, Reedik, Männistö, Satu, Marenne, Gaëlle, Marten, Jonathan, Masca, Nicholas G. D., McCarthy, Mark I., Meidtner, Karina, Mihailov, Evelin, Moilanen, Leena, Moitry, Marie, Mook-Kanamori, Dennis O., Morgan, Anna, Morris, Andrew P., Müller-Nurasyid, Martina, Munroe, Patricia B., Narisu, Narisu, Nelson, Christopher P., Neville, Matt, Ntalla, Ioanna, O’Connell, Jeffrey R., Owen, Katharine R., Pedersen, Oluf, Peloso, Gina M., Pennell, Craig E., Perola, Markus, Perry, James A., Perry, John R. B., Pers, Tune H., Ewing, Ailith, Polasek, Ozren, Raitakari, Olli T., Rasheed, Asif, Raulerson, Chelsea K., Rauramaa, Rainer, Reilly, Dermot F., Reiner, Alex P., Ridker, Paul M., Rivas, Manuel A., Robertson, Neil R., Robino, Antonietta, Rudan, Igor, Ruth, Katherine S., Saleheen, Danish, Salomaa, Veikko, Samani, Nilesh J., Schreiner, Pamela J., Schulze, Matthias B., Scott, Robert A., Segura-Lepe, Marcelo, Sim, Xueling, Slater, Andrew J., Small, Kerrin S., Smith, Blair H., Smith, Jennifer A., Southam, Lorraine, Spector, Timothy D., Speliotes, Elizabeth K., Stefansson, Kari, Steinthorsdottir, Valgerdur, Stirrups, Kathleen E., Strauch, Konstantin, Stringham, Heather M., Stumvoll, Michael, Sun, Liang, Surendran, Praveen, Swart, Karin M. A., Tardif, Jean-Claude, Taylor, Kent D., Teumer, Alexander, Thompson, Deborah J., Thorleifsson, Gudmar, Thorsteinsdottir, Unnur, Thuesen, Betina H., Tönjes, Anke, Torres, Mina, Tsafantakis, Emmanouil, Tuomilehto, Jaakko, Uitterlinden, André G., Uusitupa, Matti, van Duijn, Cornelia M., Vanhala, Mauno, Varma, Rohit, Vermeulen, Sita H., Vestergaard, Henrik, Vitart, Veronique, Vogt, Thomas F., Vuckovic, Dragana, Wagenknecht, Lynne E., Walker, Mark, Wallentin, Lars, Wang, Feijie, Wang, Carol A., Wang, Shuai, Wareham, Nicholas J., Warren, Helen R., Waterworth, Dawn M., Wessel, Jennifer, White, Harvey D., Willer, Cristen J., Wilson, James G., Wood, Andrew R., Wu, Ying, Yaghootkar, Hanieh, Yao, Jie, Yerges-Armstrong, Laura M., Young, Robin, Zeggini, Eleftheria, Zhan, Xiaowei, Zhang, Weihua, Zhao, Jing Hua, Zhao, Wei, Zheng, He, Zhou, Wei, Zillikens, M. Carola, Rivadeneira, Fernando, Borecki, Ingrid B., Pospisilik, J. Andrew, Deloukas, Panos, Frayling, Timothy M., Lettre, Guillaume, Mohlke, Karen L., Rotter, Jerome I., Kutalik, Zoltán, Hirschhorn, Joel N., Cupples, L. Adrienne, Loos, Ruth J. F., North, Kari E., and Lindgren, Cecilia M.
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- 2019
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190. Karim Khan Zand
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Perry, John R., author. and Perry, John R., author.
- Published
- 2006
191. A Genome-Wide Association Meta-Analysis of Circulating Sex Hormone–Binding Globulin Reveals Multiple Loci Implicated in Sex Steroid Hormone Regulation
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Coviello, Andrea D, Haring, Robin, Wellons, Melissa, Vaidya, Dhananjay, Lehtimäki, Terho, Keildson, Sarah, Lunetta, Kathryn L, He, Chunyan, Fornage, Myriam, Lagou, Vasiliki, Mangino, Massimo, Onland-Moret, N Charlotte, Chen, Brian, Eriksson, Joel, Garcia, Melissa, Liu, Yong Mei, Koster, Annemarie, Lohman, Kurt, Lyytikäinen, Leo-Pekka, Petersen, Ann-Kristin, Prescott, Jennifer, Stolk, Lisette, Vandenput, Liesbeth, Wood, Andrew R, Zhuang, Wei Vivian, Ruokonen, Aimo, Hartikainen, Anna-Liisa, Pouta, Anneli, Bandinelli, Stefania, Biffar, Reiner, Brabant, Georg, Cox, David G, Chen, Yuhui, Cummings, Steven, Ferrucci, Luigi, Gunter, Marc J, Hankinson, Susan E, Martikainen, Hannu, Hofman, Albert, Homuth, Georg, Illig, Thomas, Jansson, John-Olov, Johnson, Andrew D, Karasik, David, Karlsson, Magnus, Kettunen, Johannes, Kiel, Douglas P, Kraft, Peter, Liu, Jingmin, Ljunggren, Östen, Lorentzon, Mattias, Maggio, Marcello, Markus, Marcello RP, Mellström, Dan, Miljkovic, Iva, Mirel, Daniel, Nelson, Sarah, Papunen, Laure Morin, Peeters, Petra HM, Prokopenko, Inga, Raffel, Leslie, Reincke, Martin, Reiner, Alex P, Rexrode, Kathryn, Rivadeneira, Fernando, Schwartz, Stephen M, Siscovick, David, Soranzo, Nicole, Stöckl, Doris, Tworoger, Shelley, Uitterlinden, André G, van Gils, Carla H, Vasan, Ramachandran S, Wichmann, H-Erich, Zhai, Guangju, Bhasin, Shalender, Bidlingmaier, Martin, Chanock, Stephen J, De Vivo, Immaculata, Harris, Tamara B, Hunter, David J, Kähönen, Mika, Liu, Simin, Ouyang, Pamela, Spector, Tim D, van der Schouw, Yvonne T, Viikari, Jorma, Wallaschofski, Henri, McCarthy, Mark I, Frayling, Timothy M, Murray, Anna, Franks, Steve, Järvelin, Marjo-Riitta, de Jong, Frank H, Raitakari, Olli, Teumer, Alexander, Ohlsson, Claes, Murabito, Joanne M, and Perry, John RB
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Biological Sciences ,Genetics ,Breast Cancer ,Aging ,Estrogen ,Cancer Genomics ,Urologic Diseases ,Cancer ,Prostate Cancer ,Human Genome ,Women's Health ,Aetiology ,2.1 Biological and endogenous factors ,Metabolic and endocrine ,Alleles ,Female ,Genetic Heterogeneity ,Genome-Wide Association Study ,Gonadal Steroid Hormones ,Humans ,Male ,Metabolic Networks and Pathways ,Polymorphism ,Single Nucleotide ,Sex Characteristics ,Sex Hormone-Binding Globulin ,Developmental Biology - Abstract
Sex hormone-binding globulin (SHBG) is a glycoprotein responsible for the transport and biologic availability of sex steroid hormones, primarily testosterone and estradiol. SHBG has been associated with chronic diseases including type 2 diabetes (T2D) and with hormone-sensitive cancers such as breast and prostate cancer. We performed a genome-wide association study (GWAS) meta-analysis of 21,791 individuals from 10 epidemiologic studies and validated these findings in 7,046 individuals in an additional six studies. We identified twelve genomic regions (SNPs) associated with circulating SHBG concentrations. Loci near the identified SNPs included SHBG (rs12150660, 17p13.1, p = 1.8 × 10(-106)), PRMT6 (rs17496332, 1p13.3, p = 1.4 × 10(-11)), GCKR (rs780093, 2p23.3, p = 2.2 × 10(-16)), ZBTB10 (rs440837, 8q21.13, p = 3.4 × 10(-09)), JMJD1C (rs7910927, 10q21.3, p = 6.1 × 10(-35)), SLCO1B1 (rs4149056, 12p12.1, p = 1.9 × 10(-08)), NR2F2 (rs8023580, 15q26.2, p = 8.3 × 10(-12)), ZNF652 (rs2411984, 17q21.32, p = 3.5 × 10(-14)), TDGF3 (rs1573036, Xq22.3, p = 4.1 × 10(-14)), LHCGR (rs10454142, 2p16.3, p = 1.3 × 10(-07)), BAIAP2L1 (rs3779195, 7q21.3, p = 2.7 × 10(-08)), and UGT2B15 (rs293428, 4q13.2, p = 5.5 × 10(-06)). These genes encompass multiple biologic pathways, including hepatic function, lipid metabolism, carbohydrate metabolism and T2D, androgen and estrogen receptor function, epigenetic effects, and the biology of sex steroid hormone-responsive cancers including breast and prostate cancer. We found evidence of sex-differentiated genetic influences on SHBG. In a sex-specific GWAS, the loci 4q13.2-UGT2B15 was significant in men only (men p = 2.5 × 10(-08), women p = 0.66, heterogeneity p = 0.003). Additionally, three loci showed strong sex-differentiated effects: 17p13.1-SHBG and Xq22.3-TDGF3 were stronger in men, whereas 8q21.12-ZBTB10 was stronger in women. Conditional analyses identified additional signals at the SHBG gene that together almost double the proportion of variance explained at the locus. Using an independent study of 1,129 individuals, all SNPs identified in the overall or sex-differentiated or conditional analyses explained ~15.6% and ~8.4% of the genetic variation of SHBG concentrations in men and women, respectively. The evidence for sex-differentiated effects and allelic heterogeneity highlight the importance of considering these features when estimating complex trait variance.
- Published
- 2012
192. Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals.
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Dastani, Zari, Hivert, Marie-France, Timpson, Nicholas, Perry, John RB, Yuan, Xin, Scott, Robert A, Henneman, Peter, Heid, Iris M, Kizer, Jorge R, Lyytikäinen, Leo-Pekka, Fuchsberger, Christian, Tanaka, Toshiko, Morris, Andrew P, Small, Kerrin, Isaacs, Aaron, Beekman, Marian, Coassin, Stefan, Lohman, Kurt, Qi, Lu, Kanoni, Stavroula, Pankow, James S, Uh, Hae-Won, Wu, Ying, Bidulescu, Aurelian, Rasmussen-Torvik, Laura J, Greenwood, Celia MT, Ladouceur, Martin, Grimsby, Jonna, Manning, Alisa K, Liu, Ching-Ti, Kooner, Jaspal, Mooser, Vincent E, Vollenweider, Peter, Kapur, Karen A, Chambers, John, Wareham, Nicholas J, Langenberg, Claudia, Frants, Rune, Willems-Vandijk, Ko, Oostra, Ben A, Willems, Sara M, Lamina, Claudia, Winkler, Thomas W, Psaty, Bruce M, Tracy, Russell P, Brody, Jennifer, Chen, Ida, Viikari, Jorma, Kähönen, Mika, Pramstaller, Peter P, Evans, David M, St Pourcain, Beate, Sattar, Naveed, Wood, Andrew R, Bandinelli, Stefania, Carlson, Olga D, Egan, Josephine M, Böhringer, Stefan, van Heemst, Diana, Kedenko, Lyudmyla, Kristiansson, Kati, Nuotio, Marja-Liisa, Loo, Britt-Marie, Harris, Tamara, Garcia, Melissa, Kanaya, Alka, Haun, Margot, Klopp, Norman, Wichmann, H-Erich, Deloukas, Panos, Katsareli, Efi, Couper, David J, Duncan, Bruce B, Kloppenburg, Margreet, Adair, Linda S, Borja, Judith B, DIAGRAM+ Consortium, MAGIC Consortium, GLGC Investigators, MuTHER Consortium, Wilson, James G, Musani, Solomon, Guo, Xiuqing, Johnson, Toby, Semple, Robert, Teslovich, Tanya M, Allison, Matthew A, Redline, Susan, Buxbaum, Sarah G, Mohlke, Karen L, Meulenbelt, Ingrid, Ballantyne, Christie M, Dedoussis, George V, Hu, Frank B, Liu, Yongmei, Paulweber, Bernhard, Spector, Timothy D, Slagboom, P Eline, Ferrucci, Luigi, and Jula, Antti
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DIAGRAM+ Consortium ,MAGIC Consortium ,GLGC Investigators ,MuTHER Consortium ,DIAGRAM Consortium ,GIANT Consortium ,Global B Pgen Consortium ,Procardis Consortium ,MAGIC investigators ,GLGC Consortium ,Humans ,Diabetes Mellitus ,Type 2 ,Insulin Resistance ,Genetic Predisposition to Disease ,Glucose Tolerance Test ,Waist-Hip Ratio ,Gene Expression ,Polymorphism ,Single Nucleotide ,African Americans ,Asian Continental Ancestry Group ,European Continental Ancestry Group ,Female ,Male ,Adiponectin ,Cholesterol ,HDL ,Metabolic Networks and Pathways ,Genome-Wide Association Study ,Diabetes Mellitus ,Type 2 ,Polymorphism ,Single Nucleotide ,Cholesterol ,HDL ,Genetics ,Developmental Biology - Abstract
Circulating levels of adiponectin, a hormone produced predominantly by adipocytes, are highly heritable and are inversely associated with type 2 diabetes mellitus (T2D) and other metabolic traits. We conducted a meta-analysis of genome-wide association studies in 39,883 individuals of European ancestry to identify genes associated with metabolic disease. We identified 8 novel loci associated with adiponectin levels and confirmed 2 previously reported loci (P = 4.5×10(-8)-1.2×10(-43)). Using a novel method to combine data across ethnicities (N = 4,232 African Americans, N = 1,776 Asians, and N = 29,347 Europeans), we identified two additional novel loci. Expression analyses of 436 human adipocyte samples revealed that mRNA levels of 18 genes at candidate regions were associated with adiponectin concentrations after accounting for multiple testing (p
- Published
- 2012
193. Genetic determinants of serum testosterone concentrations in men.
- Author
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Ohlsson, Claes, Wallaschofski, Henri, Lunetta, Kathryn L, Stolk, Lisette, Perry, John RB, Koster, Annemarie, Petersen, Ann-Kristin, Eriksson, Joel, Lehtimäki, Terho, Huhtaniemi, Ilpo T, Hammond, Geoffrey L, Maggio, Marcello, Coviello, Andrea D, EMAS Study Group, Ferrucci, Luigi, Heier, Margit, Hofman, Albert, Holliday, Kate L, Jansson, John-Olov, Kähönen, Mika, Karasik, David, Karlsson, Magnus K, Kiel, Douglas P, Liu, Yongmei, Ljunggren, Osten, Lorentzon, Mattias, Lyytikäinen, Leo-Pekka, Meitinger, Thomas, Mellström, Dan, Melzer, David, Miljkovic, Iva, Nauck, Matthias, Nilsson, Maria, Penninx, Brenda, Pye, Stephen R, Vasan, Ramachandran S, Reincke, Martin, Rivadeneira, Fernando, Tajar, Abdelouahid, Teumer, Alexander, Uitterlinden, André G, Ulloor, Jagadish, Viikari, Jorma, Völker, Uwe, Völzke, Henry, Wichmann, H Erich, Wu, Tsung-Sheng, Zhuang, Wei Vivian, Ziv, Elad, Wu, Frederick CW, Raitakari, Olli, Eriksson, Anna, Bidlingmaier, Martin, Harris, Tamara B, Murray, Anna, de Jong, Frank H, Murabito, Joanne M, Bhasin, Shalender, Vandenput, Liesbeth, and Haring, Robin
- Subjects
EMAS Study Group ,Chromosomes ,Human ,X ,Humans ,Testosterone ,Sex Hormone-Binding Globulin ,Nuclear Proteins ,Body Mass Index ,Polymorphism ,Single Nucleotide ,Alleles ,Adult ,Aged ,80 and over ,Middle Aged ,Male ,Genome-Wide Association Study ,Aged ,and over ,Chromosomes ,Human ,X ,Polymorphism ,Single Nucleotide ,Genetics ,Developmental Biology - Abstract
Testosterone concentrations in men are associated with cardiovascular morbidity, osteoporosis, and mortality and are affected by age, smoking, and obesity. Because of serum testosterone's high heritability, we performed a meta-analysis of genome-wide association data in 8,938 men from seven cohorts and followed up the genome-wide significant findings in one in silico (n = 871) and two de novo replication cohorts (n = 4,620) to identify genetic loci significantly associated with serum testosterone concentration in men. All these loci were also associated with low serum testosterone concentration defined as
- Published
- 2011
194. Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index
- Author
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Speliotes, Elizabeth K, Willer, Cristen J, Berndt, Sonja I, Monda, Keri L, Thorleifsson, Gudmar, Jackson, Anne U, Allen, Hana Lango, Lindgren, Cecilia M, Luan, Jian'an, Mägi, Reedik, Randall, Joshua C, Vedantam, Sailaja, Winkler, Thomas W, Qi, Lu, Workalemahu, Tsegaselassie, Heid, Iris M, Steinthorsdottir, Valgerdur, Stringham, Heather M, Weedon, Michael N, Wheeler, Eleanor, Wood, Andrew R, Ferreira, Teresa, Weyant, Robert J, Segrè, Ayellet V, Estrada, Karol, Liang, Liming, Nemesh, James, Park, Ju-Hyun, Gustafsson, Stefan, Kilpeläinen, Tuomas O, Yang, Jian, Bouatia-Naji, Nabila, Esko, Tõnu, Feitosa, Mary F, Kutalik, Zoltán, Mangino, Massimo, Raychaudhuri, Soumya, Scherag, Andre, Smith, Albert Vernon, Welch, Ryan, Zhao, Jing Hua, Aben, Katja K, Absher, Devin M, Amin, Najaf, Dixon, Anna L, Fisher, Eva, Glazer, Nicole L, Goddard, Michael E, Heard-Costa, Nancy L, Hoesel, Volker, Hottenga, Jouke-Jan, Johansson, Åsa, Johnson, Toby, Ketkar, Shamika, Lamina, Claudia, Li, Shengxu, Moffatt, Miriam F, Myers, Richard H, Narisu, Narisu, Perry, John RB, Peters, Marjolein J, Preuss, Michael, Ripatti, Samuli, Rivadeneira, Fernando, Sandholt, Camilla, Scott, Laura J, Timpson, Nicholas J, Tyrer, Jonathan P, van Wingerden, Sophie, Watanabe, Richard M, White, Charles C, Wiklund, Fredrik, Barlassina, Christina, Chasman, Daniel I, Cooper, Matthew N, Jansson, John-Olov, Lawrence, Robert W, Pellikka, Niina, Prokopenko, Inga, Shi, Jianxin, Thiering, Elisabeth, Alavere, Helene, Alibrandi, Maria TS, Almgren, Peter, Arnold, Alice M, Aspelund, Thor, Atwood, Larry D, Balkau, Beverley, Balmforth, Anthony J, Bennett, Amanda J, Ben-Shlomo, Yoav, Bergman, Richard N, Bergmann, Sven, Biebermann, Heike, Blakemore, Alexandra IF, Boes, Tanja, Bonnycastle, Lori L, Bornstein, Stefan R, Brown, Morris J, and Buchanan, Thomas A
- Subjects
Biological Sciences ,Genetics ,Prevention ,Human Genome ,Body Height ,Body Mass Index ,Body Size ,Body Weight ,Chromosome Mapping ,Genetic Predisposition to Disease ,Genome-Wide Association Study ,Humans ,Obesity ,Polymorphism ,Single Nucleotide ,White People ,MAGIC ,Procardis Consortium ,Medical and Health Sciences ,Developmental Biology ,Agricultural biotechnology ,Bioinformatics and computational biology - Abstract
Obesity is globally prevalent and highly heritable, but its underlying genetic factors remain largely elusive. To identify genetic loci for obesity susceptibility, we examined associations between body mass index and ∼ 2.8 million SNPs in up to 123,865 individuals with targeted follow up of 42 SNPs in up to 125,931 additional individuals. We confirmed 14 known obesity susceptibility loci and identified 18 new loci associated with body mass index (P < 5 × 10⁻⁸), one of which includes a copy number variant near GPRC5B. Some loci (at MC4R, POMC, SH2B1 and BDNF) map near key hypothalamic regulators of energy balance, and one of these loci is near GIPR, an incretin receptor. Furthermore, genes in other newly associated loci may provide new insights into human body weight regulation.
- Published
- 2010
195. Hundreds of variants clustered in genomic loci and biological pathways affect human height
- Author
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Lango Allen, Hana, Estrada, Karol, Lettre, Guillaume, Berndt, Sonja I, Weedon, Michael N, Rivadeneira, Fernando, Willer, Cristen J, Jackson, Anne U, Vedantam, Sailaja, Raychaudhuri, Soumya, Ferreira, Teresa, Wood, Andrew R, Weyant, Robert J, Segrè, Ayellet V, Speliotes, Elizabeth K, Wheeler, Eleanor, Soranzo, Nicole, Park, Ju-Hyun, Yang, Jian, Gudbjartsson, Daniel, Heard-Costa, Nancy L, Randall, Joshua C, Qi, Lu, Vernon Smith, Albert, Mägi, Reedik, Pastinen, Tomi, Liang, Liming, Heid, Iris M, Luan, Jian’an, Thorleifsson, Gudmar, Winkler, Thomas W, Goddard, Michael E, Sin Lo, Ken, Palmer, Cameron, Workalemahu, Tsegaselassie, Aulchenko, Yurii S, Johansson, Åsa, Carola Zillikens, M, Feitosa, Mary F, Esko, Tõnu, Johnson, Toby, Ketkar, Shamika, Kraft, Peter, Mangino, Massimo, Prokopenko, Inga, Absher, Devin, Albrecht, Eva, Ernst, Florian, Glazer, Nicole L, Hayward, Caroline, Hottenga, Jouke-Jan, Jacobs, Kevin B, Knowles, Joshua W, Kutalik, Zoltán, Monda, Keri L, Polasek, Ozren, Preuss, Michael, Rayner, Nigel W, Robertson, Neil R, Steinthorsdottir, Valgerdur, Tyrer, Jonathan P, Voight, Benjamin F, Wiklund, Fredrik, Xu, Jianfeng, Hua Zhao, Jing, Nyholt, Dale R, Pellikka, Niina, Perola, Markus, Perry, John RB, Surakka, Ida, Tammesoo, Mari-Liis, Altmaier, Elizabeth L, Amin, Najaf, Aspelund, Thor, Bhangale, Tushar, Boucher, Gabrielle, Chasman, Daniel I, Chen, Constance, Coin, Lachlan, Cooper, Matthew N, Dixon, Anna L, Gibson, Quince, Grundberg, Elin, Hao, Ke, Juhani Junttila, M, Kaplan, Lee M, Kettunen, Johannes, König, Inke R, Kwan, Tony, Lawrence, Robert W, Levinson, Douglas F, Lorentzon, Mattias, McKnight, Barbara, Morris, Andrew P, Müller, Martina, Suh Ngwa, Julius, Purcell, Shaun, Rafelt, Suzanne, Salem, Rany M, and Salvi, Erika
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Biological Sciences ,Genetics ,Health Sciences ,Mathematical Sciences ,Statistics ,Human Genome ,Clinical Research ,Biotechnology ,Aetiology ,2.1 Biological and endogenous factors ,Body Height ,Chromosomes ,Human ,Pair 3 ,Genetic Loci ,Genetic Predisposition to Disease ,Genome ,Human ,Genome-Wide Association Study ,Humans ,Metabolic Networks and Pathways ,Multifactorial Inheritance ,Phenotype ,Polymorphism ,Single Nucleotide ,General Science & Technology - Abstract
Most common human traits and diseases have a polygenic pattern of inheritance: DNA sequence variants at many genetic loci influence the phenotype. Genome-wide association (GWA) studies have identified more than 600 variants associated with human traits, but these typically explain small fractions of phenotypic variation, raising questions about the use of further studies. Here, using 183,727 individuals, we show that hundreds of genetic variants, in at least 180 loci, influence adult height, a highly heritable and classic polygenic trait. The large number of loci reveals patterns with important implications for genetic studies of common human diseases and traits. First, the 180 loci are not random, but instead are enriched for genes that are connected in biological pathways (P = 0.016) and that underlie skeletal growth defects (P
- Published
- 2010
196. Inventory of Parent and Peer Attachment—Revised Scores in Adolescents: A Psychometric and Person-Oriented Study
- Author
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Andretta, James R., McKay, Michael T., Harvey, Séamus A., and Perry, John L.
- Published
- 2017
197. Flue-gas and direct-air capture of CO₂ by porous metal—organic materials
- Author
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Madden, David G., Scott, Hayley S., Kumar, Amrit, Chen, Kai-Jie, Sanii, Rana, Bajpai, Alankriti, Lusi, Matteo, Curtin, Teresa, Perry, John J., and Zaworotko, Michael J.
- Published
- 2017
198. Genome-wide analysis of promoter contacts identifies novel regulators of late-stage adipogenesis
- Author
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Sandovici, Ionel, primary, Mifsud, Borbala, additional, Emery, Amy, additional, Gulati, Pawan, additional, Kentistou, Katherine A., additional, Banu, Ayesha, additional, Campbell, Niamh, additional, Hardwick, Bryn S., additional, Crooks, Alex T., additional, Fernandez-Twinn, Denise S., additional, Mennitti, Lais V., additional, Srour, Luma, additional, Awad, Sherine, additional, Chiarugi, Davide, additional, Hamilton, Russell S., additional, Wingett, Steven W., additional, Fraser, Peter, additional, Ong, Ken K., additional, Schoenfelder, Stefan, additional, Mohammad, Farhan, additional, O’Rahilly, Stephen, additional, Perry, John R.B., additional, Venkitaraman, Ashok R., additional, Ozanne, Susan E., additional, and Constância, Miguel, additional
- Published
- 2023
- Full Text
- View/download PDF
199. Prevalence of Deleterious Variants in MC3R in Patients With Constitutional Delay of Growth and Puberty
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Duckett, Katie, primary, Williamson, Alice, additional, Kincaid, John W R, additional, Rainbow, Kara, additional, Corbin, Laura J, additional, Martin, Hilary C, additional, Eberhardt, Ruth Y, additional, Huang, Qin Qin, additional, Hurles, Matthew E, additional, He, Wen, additional, Brauner, Raja, additional, Delaney, Angela, additional, Dunkel, Leo, additional, Grinspon, Romina P, additional, Hall, Janet E, additional, Hirschhorn, Joel N, additional, Howard, Sasha R, additional, Latronico, Ana C, additional, Jorge, Alexander A L, additional, McElreavey, Ken, additional, Mericq, Verónica, additional, Merino, Paulina M, additional, Palmert, Mark R, additional, Plummer, Lacey, additional, Rey, Rodolfo A, additional, Rezende, Raíssa C, additional, Seminara, Stephanie B, additional, Salnikov, Kathryn, additional, Banerjee, Indraneel, additional, Lam, Brian Y H, additional, Perry, John R B, additional, Timpson, Nicholas J, additional, Clayton, Peter, additional, Chan, Yee-Ming, additional, Ong, Ken K, additional, and O’Rahilly, Stephen, additional
- Published
- 2023
- Full Text
- View/download PDF
200. Protein-truncating variants inBSNare associated with severe adult-onset obesity, type 2 diabetes and fatty liver disease
- Author
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Zhao, Yajie, primary, Chukanova, Maria, additional, Kentistou, Katherine A, additional, Fairhurst-Hunter, Zammy, additional, Siegert, Anna Maria, additional, Jia, Raina, additional, Dowsett, Georgina, additional, Gardner, Eugene J, additional, Day, Felix R, additional, Kaisinger, Lena R, additional, Tung, Yi-Chun Loraine, additional, Hong Lam, Brian Yee, additional, Chen, Hsiao-Jou Cortina, additional, Wang, Quanli, additional, Berumen-Campos, Jaime, additional, Kuri-Morales, Pablo, additional, Tapia-Conyer, Roberto, additional, Alegre-Diaz, Jesus, additional, Emberson, Jonathan, additional, Torres, Jason M, additional, Collins, Rory, additional, Saleheen, Danish, additional, Smith, Katherine R, additional, Paul, Dirk S, additional, Merkle, Florian, additional, Wareham, Nick J, additional, Petrovski, Slavé, additional, O’Rahilly, Steve, additional, Ong, Ken K, additional, Yeo, Giles S H, additional, and Perry, John R B, additional
- Published
- 2023
- Full Text
- View/download PDF
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