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153. An aggressive early gastric cancer: Kodama's PenA type

Author

Morgagni, Paolo, primary, Solaini, Leonardo, additional, Saragoni, Luca, additional, Bencivenga, Maria, additional, Fumagalli Romario, Uberto, additional, Graziosi, Luigina, additional, Marino, Elisabetta, additional, Marrelli, Daniele, additional, Rausei, Stefano, additional, Rosa, Fausto, additional, Scarpi, Emanuela, additional, Tomezzoli, Anna, additional, Tringali, Domenico, additional, Vindigni, Carla, additional, Vittimberga, Giovanni, additional, and Roviello, Franco, additional

Published
2018
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154. Prognostic Indicators in Stage IV Surgically Treated Gastric Cancer Patients: A Retrospective Multi-Institutional Study

Author

Biondi, Alberto, primary, D’Ugo, Domenico, additional, Cananzi, Ferdinando, additional, Rausei, Stefano, additional, Sicoli, Federico, additional, Santullo, Francesco, additional, Laurino, Antonio, additional, Ruspi, Laura, additional, Belia, Francesco, additional, Quagliuolo, Vittorio, additional, and Persiani, Roberto, additional

Published
2018
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155. Enhanced recovery program for oncologic gastric surgery. Compliance and outcomes in an Italian, prospective, multicenter study

Author

Gianotti, Luca, primary, Sandini, Marta, additional, De Pascale, Stefano, additional, Rausei, Stefano, additional, Weindelmayer, Jacopo, additional, Bencini, Lapo, additional, Rosati, RIccardo, additional, Corattii, Andrea, additional, Sansonetti, Andrea, additional, Cussu, Andrea, additional, and Fumagalli, Uberto, additional

Published
2018
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156. Early Gastric Cancer: Clinical Behavior and Treatment Options. Results of an Italian Multicenter Study on Behalf of the Italian Gastric Cancer Research Group (GIRCG)

Author

Saragoni, Luca, primary, Scarpi, Emanuela, additional, Ravaioli, Alessandra, additional, Morgagni, Paolo, additional, Roviello, Franco, additional, Vindigni, Carla, additional, Rausei, Stefano, additional, Chiaravalli, Anna Maria, additional, Fumagalli, Uberto, additional, Spaggiari, Paola, additional, Rosa, Fausto, additional, Ricci, Riccardo, additional, Donini, Annibale, additional, Giovenali, Paolo, additional, Tomezzoli, Anna, additional, and De Manzoni, Giovanni, additional

Published
2018
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157. Preoperative or Perioperative Docetaxel, Oxaliplatin, Capecitabine Gastrodoc Regimen in Patients with Locally Advanced Resectable Gastric Cancer: A Randomized Phase II Trial

Author

Monti, Manlio, primary, Morgagni, Paolo, additional, Nanni, Oriana, additional, Framarini, Massimo, additional, Saragoni, Luca, additional, Marrelli, Daniele, additional, Roviello, Franco, additional, Petrioli, Roberto, additional, Fumagalli Romario, Uberto, additional, Rimassa, Lorenza, additional, Bozzarelli, Silvia, additional, Donini, Annibale, additional, Graziosi, Luigina, additional, De Angelis, Verena, additional, De Manzoni, Giovanni, additional, Bencivenga, Maria, additional, Mengardo, Valentina, additional, Parma, Emilio, additional, Milandri, Carlo, additional, Mura, Gianni, additional, Signorini, Alessandra, additional, Baiocchi, Gianluca, additional, Molfino, Sarah, additional, Sgroi, Giovanni, additional, Steccanella, Francesca, additional, Rausei, Stefano, additional, Proserpio, Ilaria, additional, Viganò, Jacopo, additional, Brugnatelli, Silvia, additional, Rinnovati, Andrea, additional, Santi, Stefano, additional, Foca, Flavia, additional, Valmorri, Linda, additional, Amadori, Dino, additional, and Luca Frassineti, Giovanni, additional

Published
2018
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159. Unusual acute abdomen: to operate or not to operate?

Author

Persiani, Roberto, Biondi, Alberto, Buccelletti, Francesco, Rausei, Stefano, and Silveri, NicolA[sup.2] Gentiloni

Subjects
Acute abdomen -- Diagnosis, Acute abdomen -- Care and treatment, Surgery -- Usage
Published
2006

161. Erratum to: IROA: International Register of Open Abdomen, preliminary results

Author

Coccolini, Federico, primary, Montori, Giulia, additional, Ceresoli, Marco, additional, Catena, Fausto, additional, Ivatury, Rao, additional, Sugrue, Michael, additional, Sartelli, Massimo, additional, Fugazzola, Paola, additional, Corbella, Davide, additional, Salvetti, Francesco, additional, Negoi, Ionut, additional, Zese, Monica, additional, Occhionorelli, Savino, additional, Maccatrozzo, Stefano, additional, Shlyapnikov, Sergei, additional, Galatioto, Christian, additional, Chiarugi, Massimo, additional, Demetrashvili, Zaza, additional, Dondossola, Daniele, additional, Yovtchev, Yovcho, additional, Ioannidis, Orestis, additional, Novelli, Giuseppe, additional, Nacoti, Mirco, additional, Khor, Desmond, additional, Inaba, Kenji, additional, Demetriades, Demetrios, additional, Kaussen, Torsten, additional, Jusoh, Asri Che, additional, Ghannam, Wagih, additional, Sakakushev, Boris, additional, Guetta, Ohad, additional, Dogjani, Agron, additional, Costa, Stefano, additional, Singh, Sandeep, additional, Damaskos, Dimitrios, additional, Isik, Arda, additional, Yuan, Kuo-Ching, additional, Trotta, Francesco, additional, Rausei, Stefano, additional, Martinez-Perez, Aleix, additional, Bellanova, Giovanni, additional, Fonseca, Vinicius Cordeiro, additional, Hernández, Fernando, additional, Marinis, Athanasios, additional, Fernandes, Wellington, additional, Quiodettis, Martha, additional, Bala, Miklosh, additional, Vereczkei, Andras, additional, Curado, Rafael L., additional, Fraga, Gustavo Pereira, additional, Pereira, Bruno M., additional, Gachabayov, Mahir, additional, Chagerben, Guillermo Perez, additional, Arellano, Miguel Leon, additional, Ozyazici, Sefa, additional, Costa, Gianluca, additional, Tezcaner, Tugan, additional, and Ansaloni, Luca, additional

Published
2017
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162. IROA: International Register of Open Abdomen, preliminary results

Author

Coccolini, Federico, primary, Montori, Giulia, additional, Ceresoli, Marco, additional, Catena, Fausto, additional, Ivatury, Rao, additional, Sugrue, Michael, additional, Sartelli, Massimo, additional, Fugazzola, Paola, additional, Corbella, Davide, additional, Salvetti, Francesco, additional, Negoi, Ionut, additional, Zese, Monica, additional, Occhionorelli, Savino, additional, Maccatrozzo, Stefano, additional, Shlyapnikov, Sergei, additional, Galatioto, Christian, additional, Chiarugi, Massimo, additional, Demetrashvili, Zaza, additional, Dondossola, Daniele, additional, Yovtchev, Yovcho, additional, Ioannidis, Orestis, additional, Novelli, Giuseppe, additional, Nacoti, Mirco, additional, Khor, Desmond, additional, Inaba, Kenji, additional, Demetriades, Demetrios, additional, Kaussen, Torsten, additional, Jusoh, Asri Che, additional, Ghannam, Wagih, additional, Sakakushev, Boris, additional, Guetta, Ohad, additional, Dogjani, Agron, additional, Costa, Stefano, additional, Singh, Sandeep, additional, Damaskos, Dimitrios, additional, Isik, Arda, additional, Yuan, Kuo-Ching, additional, Trotta, Francesco, additional, Rausei, Stefano, additional, Martinez-Perez, Aleix, additional, Bellanova, Giovanni, additional, Fonseca, Vinicius Cordeiro, additional, Hernández, Fernando, additional, Marinis, Athanasios, additional, Fernandes, Wellington, additional, Quiodettis, Martha, additional, Bala, Miklosh, additional, Vereczkei, Andras, additional, Curado, Rafael L., additional, Fraga, Gustavo Pereira, additional, Pereira, Bruno M., additional, Gachabayov, Mahir, additional, Chagerben, Guillermo Perez, additional, Arellano, Miguel Leon, additional, Ozyazici, Sefa, additional, Costa, Gianluca, additional, Tezcaner, Tugan, additional, and Ansaloni, Luca, additional

Published
2017
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168. Prognostic Indicators in Stage IV Surgically Treated Gastric Cancer Patients: A Retrospective Multi-Institutional Study.

Author

Biondi, Alberto, D'Ugo, Domenico, Cananzi, Ferdinando, Rausei, Stefano, Sicoli, Federico, Santullo, Francesco, Laurino, Antonio, Ruspi, Laura, Belia, Francesco, Quagliuolo, Vittorio, and Persiani, Roberto

Subjects
STOMACH cancer, CANCER patients, GASTRECTOMY, ELECTIVE surgery, ADJUVANT treatment of cancer, LYMPHADENECTOMY
Abstract

Introduction: The role of gastric resection in treating metastatic gastric adenocarcinoma is controversial. In the present study, we reviewed the short- and long-term outcomes of stage IV patients undergoing surgery. Methods: A retrospective review was conducted that assessed patients undergoing elective surgery for incurable gastric carcinoma. Short- and long-term results were evaluated. Results: A total of 122 stage IV gastric cancer patients were assessed. Postoperative mortality was 5.7%, and the overall rate of complications was 35.2%. The overall survival rate at 1 and 3 years was 58 and 19% respectively; the median survival was 14 months. Improved survival was observed for the factors age less than 60 years (p = 0.015), site of metastases (p = 0.022), extended lymph node dissection (p = 0.044), absence of residual disease after surgery (p = 0.001), and administration of adjuvant chemotherapy (p = 0.016). Multivariate analysis showed that residual disease and adjuvant chemotherapy were independent prognostic factors. Conclusions: The results of this study suggest that surgery combined with systemic chemotherapy in selected patients with stage IV gastric cancer can improve survival. [ABSTRACT FROM AUTHOR]

Published
2019
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171. Extended lymphadenectomy in elderly and/or highly co-morbid gastric cancer patients: A retrospective multicenter study

Author

Rausei, Stefano, Ruspi, L., Rosa, Fausto, Morgagni, P., Marrelli, D., Cossu, A., Cananzi, Ferdinando Carlo Maria, Lomonaco, R., Coniglio, A., Biondi, Alberto, Cipollari, C., Graziosi, L., Fumagalli, U., Casella, F., Bertoli, P., di Leo, A., Alfieri, Sergio, Vittimberga, G., Roviello, F., Orsenigo, E., Quagliuolo, V., Montemurro, S., Baiocchi, G., Persiani, Roberto, Bencivenga, M., Donini, A., Rosati, R., Sansonetti, A., Ansaloni, L., Zanoni, A., Galli, F., Dionigi, G., Rosa, Fausto (ORCID:0000-0002-7280-8354), Biondi, Alberto (ORCID:0000-0002-2470-7858), Alfieri, Sergio (ORCID:0000-0002-0404-724X), Persiani, Roberto (ORCID:0000-0002-1537-5097), Rausei, Stefano, Ruspi, L., Rosa, Fausto, Morgagni, P., Marrelli, D., Cossu, A., Cananzi, Ferdinando Carlo Maria, Lomonaco, R., Coniglio, A., Biondi, Alberto, Cipollari, C., Graziosi, L., Fumagalli, U., Casella, F., Bertoli, P., di Leo, A., Alfieri, Sergio, Vittimberga, G., Roviello, F., Orsenigo, E., Quagliuolo, V., Montemurro, S., Baiocchi, G., Persiani, Roberto, Bencivenga, M., Donini, A., Rosati, R., Sansonetti, A., Ansaloni, L., Zanoni, A., Galli, F., Dionigi, G., Rosa, Fausto (ORCID:0000-0002-7280-8354), Biondi, Alberto (ORCID:0000-0002-2470-7858), Alfieri, Sergio (ORCID:0000-0002-0404-724X), and Persiani, Roberto (ORCID:0000-0002-1537-5097)

Abstract

Background Gastrectomy with extended lymphadenectomy is considered the gold standard treatment for advanced gastric cancer, with no age- or comorbidity-related limitations. We evaluated the safety and efficacy of curative gastrectomy with extended nodal dissection, verifying survival in elderly and highly co-morbid patients. Methods In a retrospective multicenter study, we examined 1322 non-metastatic gastric-cancer patients that underwent curative gastrectomy with D2 versus D1 lymphadenectomy from January 2000 to December 2009. Postoperative complications, overall survival (OS), and disease-specific survival (DSS) according to age and the Charlson Comorbidity Score were analyzed in relation to the extent of lymphadenectomy. Results Postoperative morbidity was 30.4%. Complications were more frequent in highly co-morbid elderly patients, and, although general morbidity rates after D2 and D1 lymphadenectomy were similar (29.9% and 33.2%, respectively), they increased following D2 in highly co-morbid elderly patients (39.6%). D2-lymphadenectomy significantly improved 5-year OS and DSS (48.0% vs. 37.6% in D1, p < 0.001 and 72.6% vs. 58.1% in D1, p < 0.001, respectively) in all patients. In elderly patients, this benefit was present only in 5-year DSS. D2 nodal dissection induced better 5-year OS and DSS rates in elderly patients with positive nodes (29.7% vs. 21.2% in D1, p = 0.008 and 47.5% vs. 30.6% in D1, p = 0.001, respectively), although it was present only in DSS when highly co-morbid elderly patients were considered. Conclusion Extended lymphadenectomy confirmed better survival rates in gastric cancer patients. Due to high postoperative complication rate and no significant improvement of the OS, D1 lymphadenectomy should be considered in elderly and/or highly co-morbid gastric cancer patients.

Published
2016

172. Gastric GISTs: Analysis of c-Kit, PDGFRA and BRAF mutations in relation to prognosis and clinical pathological characteristics of patients – A GIRCG study

Author

Capelli, L., Petracci, E., Quagliuolo, V., Saragoni, L., Colombo, P., Morgagni, P., Calistri, D., Tomezzoli, A., Di Cosmo, M., Roviello, F., Vindigni, C., Coniglio, A., Villanacci, V., Catarci, M., Coppola, L., Alfieri, Sergio, Ricci, Riccardo, Capella, C., Rausei, Stefano, Gulino, D., Amadori, D., Ulivi, P., Alfieri, Sergio (ORCID:0000-0002-0404-724X), Ricci, Riccardo (ORCID:0000-0002-9089-5084), Capelli, L., Petracci, E., Quagliuolo, V., Saragoni, L., Colombo, P., Morgagni, P., Calistri, D., Tomezzoli, A., Di Cosmo, M., Roviello, F., Vindigni, C., Coniglio, A., Villanacci, V., Catarci, M., Coppola, L., Alfieri, Sergio, Ricci, Riccardo, Capella, C., Rausei, Stefano, Gulino, D., Amadori, D., Ulivi, P., Alfieri, Sergio (ORCID:0000-0002-0404-724X), and Ricci, Riccardo (ORCID:0000-0002-9089-5084)

Abstract

Background Gastric gastrointestinal stromal tumors (GISTs) represent a subgroup of GISTs with a better prognosis than those located in other areas. In this retrospective study we performed a molecular characterization of a large series of patients with gastric GISTs in relation to clinical–pathological characteristics and prognosis. Methods DNA was extracted from paraffin-embedded sections from 221 gastric GIST patients submitted to surgery. Exons 9, 11, 13 and 17 of KIT, exons 12 and 18 of PDGFRA and exons 11 and 15 of BRAF were analyzed by direct sequencing. Cox regression analysis adjusted for clinical–pathological factors was performed to evaluate KIT and PDGFRA mutations in relation to the composite endpoint of relapse or death. Results KIT and PDGFRA mutations were observed in 119 (53.8%) and 56 (25.3%) patients, respectively, whereas 46 (20.8%) patients had wild type (wt) disease. Univariable analyses showed that a high Miettinen risk category and the presence of ulceration and KIT deletions were associated with increased risk of relapse or death (p < 0.001; p = 0.0389 and p = 0.002, respectively). After adjusting for Miettinen risk score, KIT deletions remained an independent prognostic factor (HRadj = 2.65, 95% CI [1.15–6.13], p = 0.023). Moreover, KIT deletions in exon 11 codons 557, 558 or 559 were associated with a higher risk of relapse or death than wt tumors (HRadj = 3.29 95% CI [1.64–6.64], p = 0.001). Conclusions KIT deletions in exon 11, especially those involving codons 557, 558 or 559, were correlated with a more aggressive gastric GIST phenotype and increased risk of relapse or death.

Published
2016

173. Evidence-based Analysis on The Clinical Impact of Intraoperative Neuromonitoring in Thyroid Surgery: State of the Art and Future Perspectives

Author

Mangano, Alberto, Wu Che Wei, Lianos Georgios, D, Kim Hoon Yub, Chiang Feng Yu, Wang, Ping, Xiaoli, Liu, Hui, Sun, Teksöz, Serkan, Bukey, Yusuf, Dionigi, Gianlorenzo, and Rausei, Stefano

Abstract

Laryngeal nerve injuries are one the most critical complications during thyroid and parathyroid surgery. Iatrogenic damages to the recurrent laryngeal nerve (RLN) are relevant in terms of clinical implications, economic costs, and for malpractice litigation. In order to minimize potential neural damages, a standardized surgical technique is mandatory. Intraoperatory neuromonitoring (IONM) of the RLN is an important adjunct to the traditional approach and is a reliable tool for neural mapping and in dissection and prognostication of postoperative neural function 4. Because of this, most of the iatrogenic damages are not related to direct transection, but they are visually undetectable. Notwithstanding the increasing use of IONM at this stage, there is still the need for prospective, randomized, well-powered, and well-designed trials in order to further validate (via evidence-based data) the role of IONM in thyroid surgery. The aim of this review is to provide a critical analysis of the scientific evidences on the clinical impact of IONM in thyroid surgery showing the unsolved problems and the future challenges.

Published
2014

176. Early intact PTH (iPTH) is an early predictor of postoperative hypocalcemia for a safer and earlier hospital discharge: an analysis on 260 total thyroidectomies

Author

Inversini, Davide, primary, Rausei, Stefano, additional, Ferrari, Cesare Carlo, additional, Frattini, Francesco, additional, Anuwong, Angkoon, additional, Kim, Hoon Yub, additional, Liu, Xiaoli, additional, Wu, Chei-Wei, additional, Tian, Wen, additional, Liu, Renbin, additional, and Dionigi, Gianlorenzo, additional

Published
2016
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179. The Italian Research Group for Gastric Cancer (GIRCG) guidelines for gastric cancer staging and treatment: 2015

Author

De Manzoni, Giovanni, primary, Marrelli, Daniele, additional, Baiocchi, Gian Luca, additional, Morgagni, Paolo, additional, Saragoni, Luca, additional, Degiuli, Maurizio, additional, Donini, Annibale, additional, Fumagalli, Uberto, additional, Mazzei, Maria Antonietta, additional, Pacelli, Fabio, additional, Tomezzoli, Anna, additional, Berselli, Mattia, additional, Catalano, Filippo, additional, Di Leo, Alberto, additional, Framarini, Massimo, additional, Giacopuzzi, Simone, additional, Graziosi, Luigina, additional, Marchet, Alberto, additional, Marini, Mario, additional, Milandri, Carlo, additional, Mura, Gianni, additional, Orsenigo, Elena, additional, Quagliuolo, Vittorio, additional, Rausei, Stefano, additional, Ricci, Riccardo, additional, Rosa, Fausto, additional, Roviello, Giandomenico, additional, Sansonetti, Andrea, additional, Sgroi, Giovanni, additional, Tiberio, Guido Alberto Massimo, additional, Verlato, Giuseppe, additional, Vindigni, Carla, additional, Rosati, Riccardo, additional, and Roviello, Franco, additional

Published
2016
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182. Risk factor analysis for involvement of resection margins in gastric and esophagogastric junction cancer: an Italian multicenter study

Author

Bissolati, Massimiliano, primary, Desio, Matteo, additional, Rosa, Fausto, additional, Rausei, Stefano, additional, Marrelli, Daniele, additional, Baiocchi, Gian Luca, additional, De Manzoni, Giovanni, additional, Chiari, Damiano, additional, Guarneri, Giovanni, additional, Pacelli, Fabio, additional, De Franco, Lorenzo, additional, Molfino, Sarah, additional, Cipollari, Chiara, additional, and Orsenigo, Elena, additional

Published
2016
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185. International consensus conference on open abdomen in trauma

Author

Chiara, Osvaldo, primary, Cimbanassi, Stefania, additional, Biffl, Walter, additional, Leppaniemi, Ari, additional, Henry, Sharon, additional, Scalea, Thomas M., additional, Catena, Fausto, additional, Ansaloni, Luca, additional, Chieregato, Arturo, additional, de Blasio, Elvio, additional, Gambale, Giorgio, additional, Gordini, Giovanni, additional, Nardi, Guiseppe, additional, Paldalino, Pietro, additional, Gossetti, Francesco, additional, Dionigi, Paolo, additional, Noschese, Giuseppe, additional, Tugnoli, Gregorio, additional, Ribaldi, Sergio, additional, Sgardello, Sebastian, additional, Magnone, Stefano, additional, Rausei, Stefano, additional, Mariani, Anna, additional, Mengoli, Francesca, additional, di Saverio, Salomone, additional, Castriconi, Maurizio, additional, Coccolini, Federico, additional, Negreanu, Joseph, additional, Razzi, Salvatore, additional, Coniglio, Carlo, additional, Morelli, Francesco, additional, Buonanno, Maurizio, additional, Lippi, Monica, additional, Trotta, Liliana, additional, Volpi, Annalisa, additional, Fattori, Luca, additional, Zago, Mauro, additional, de Rai, Paolo, additional, Sammartano, Fabrizio, additional, Manfredi, Roberto, additional, and Cingolani, Emiliano, additional

Published
2016
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187. Global validation of the WSES Sepsis Severity Score for patients with complicated intra-abdominal infections: a prospective multicentre study (WISS Study)

Author

Sartelli, Massimo, primary, Abu-Zidan, Fikri M., additional, Catena, Fausto, additional, Griffiths, Ewen A., additional, Di Saverio, Salomone, additional, Coimbra, Raul, additional, Ordoñez, Carlos A., additional, Leppaniemi, Ari, additional, Fraga, Gustavo P., additional, Coccolini, Federico, additional, Agresta, Ferdinando, additional, Abbas, Asrhaf, additional, Abdel Kader, Saleh, additional, Agboola, John, additional, Amhed, Adamu, additional, Ajibade, Adesina, additional, Akkucuk, Seckin, additional, Alharthi, Bandar, additional, Anyfantakis, Dimitrios, additional, Augustin, Goran, additional, Baiocchi, Gianluca, additional, Bala, Miklosh, additional, Baraket, Oussama, additional, Bayrak, Savas, additional, Bellanova, Giovanni, additional, Beltràn, Marcelo A., additional, Bini, Roberto, additional, Boal, Matthew, additional, Borodach, Andrey V., additional, Bouliaris, Konstantinos, additional, Branger, Frederic, additional, Brunelli, Daniele, additional, Catani, Marco, additional, Che Jusoh, Asri, additional, Chichom-Mefire, Alain, additional, Cocorullo, Gianfranco, additional, Colak, Elif, additional, Costa, David, additional, Costa, Silvia, additional, Cui, Yunfeng, additional, Curca, Geanina Loredana, additional, Curry, Terry, additional, Das, Koray, additional, Delibegovic, Samir, additional, Demetrashvili, Zaza, additional, Di Carlo, Isidoro, additional, Drozdova, Nadezda, additional, El Zalabany, Tamer, additional, Enani, Mushira Abdulaziz, additional, Faro, Mario, additional, Gachabayov, Mahir, additional, Giménez Maurel, Teresa, additional, Gkiokas, Georgios, additional, Gomes, Carlos Augusto, additional, Gonsaga, Ricardo Alessandro Teixeira, additional, Guercioni, Gianluca, additional, Guner, Ali, additional, Gupta, Sanjay, additional, Gutierrez, Sandra, additional, Hutan, Martin, additional, Ioannidis, Orestis, additional, Isik, Arda, additional, Izawa, Yoshimitsu, additional, Jain, Sumita A., additional, Jokubauskas, Mantas, additional, Karamarkovic, Aleksandar, additional, Kauhanen, Saila, additional, Kaushik, Robin, additional, Kenig, Jakub, additional, Khokha, Vladimir, additional, Kim, Jae Il, additional, Kong, Victor, additional, Koshy, Renol, additional, Krasniqi, Avidyl, additional, Kshirsagar, Ashok, additional, Kuliesius, Zygimantas, additional, Lasithiotakis, Konstantinos, additional, Leão, Pedro, additional, Lee, Jae Gil, additional, Leon, Miguel, additional, Lizarazu Pérez, Aintzane, additional, Lohsiriwat, Varut, additional, López-Tomassetti Fernandez, Eudaldo, additional, Lostoridis, Eftychios, additional, Mn, Raghuveer, additional, Major, Piotr, additional, Marinis, Athanasios, additional, Marrelli, Daniele, additional, Martinez-Perez, Aleix, additional, Marwah, Sanjay, additional, McFarlane, Michael, additional, Melo, Renato Bessa, additional, Mesina, Cristian, additional, Michalopoulos, Nick, additional, Moldovanu, Radu, additional, Mouaqit, Ouadii, additional, Munyika, Akutu, additional, Negoi, Ionut, additional, Nikolopoulos, Ioannis, additional, Nita, Gabriela Elisa, additional, Olaoye, Iyiade, additional, Omari, Abdelkarim, additional, Ossa, Paola Rodríguez, additional, Ozkan, Zeynep, additional, Padmakumar, Ramakrishnapillai, additional, Pata, Francesco, additional, Pereira Junior, Gerson Alves, additional, Pereira, Jorge, additional, Pintar, Tadeja, additional, Pouggouras, Konstantinos, additional, Prabhu, Vinod, additional, Rausei, Stefano, additional, Rems, Miran, additional, Rios-Cruz, Daniel, additional, Sakakushev, Boris, additional, Sánchez de Molina, Maria Luisa, additional, Seretis, Charampolos, additional, Shelat, Vishal, additional, Simões, Romeo Lages, additional, Sinibaldi, Giovanni, additional, Skrovina, Matej, additional, Smirnov, Dmitry, additional, Spyropoulos, Charalampos, additional, Tepp, Jaan, additional, Tezcaner, Tugan, additional, Tolonen, Matti, additional, Torba, Myftar, additional, Ulrych, Jan, additional, Uzunoglu, Mustafa Yener, additional, van Dellen, David, additional, van Ramshorst, Gabrielle H., additional, Vasquez, Giorgio, additional, Venara, Aurélien, additional, Vereczkei, Andras, additional, Vettoretto, Nereo, additional, Vlad, Nutu, additional, Yadav, Sanjay Kumar, additional, Yilmaz, Tonguç Utku, additional, Yuan, Kuo-Ching, additional, Zachariah, Sanoop Koshy, additional, Zida, Maurice, additional, Zilinskas, Justas, additional, and Ansaloni, Luca, additional

Published
2015
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189. Early Versus Delayed Source Control in Open Abdomen Management for Severe Intra-abdominal Infections: A Retrospective Analysis on 111 Cases.

Author

Rausei, Stefano, Pappalardo, Vincenzo, Ruspi, Laura, Colella, Antonio, Giudici, Simone, Ardita, Vincenzo, Frattini, Francesco, Rovera, Francesca, Boni, Luigi, and Dionigi, Gianlorenzo

Subjects
*INTRA-abdominal infections, *PERITONITIS, *SEPTICEMIA treatment, *INFECTION prevention, *MORTALITY, *HEALTH outcome assessment, *THERAPEUTICS
Abstract

Background: Time to source control plays a determinant prognostic role in patients having severe intra-abdominal infections (IAIs). Open abdomen (OA) management became an effective treatment option for peritonitis. Aim of this study was to analyze the correlation between time to source control and outcome in patients presenting with abdominal sepsis and treated by OA.Methods: We retrospectively analyzed 111 patients affected by abdominal sepsis and treated with OA from May 2007 to May 2015. Patients were classified according to time interval from first patient evaluation to source control. The end points were intra-hospital mortality and primary fascial closure rate.Results: The in-hospital mortality rate was 21.6% (24/111), and the primary fascial closure rate was 90.9% (101/111). A time to source control ≥6 h resulted significantly associated with a poor prognosis and a lower fascial closure rate (mortality 27.0 vs 9.0%, p = 0.04; primary fascial closure 86 vs 100%, p = 0.02). We observed a direct increase in mortality (and a reduction in closure rate) for each 6-h delay in surgery to source control.Conclusion: Early source control using OA management significantly improves outcome of patients with severe IAIs. This damage control approach well fits to the treatment of time-related conditions, particularly in case of critically ill patients. [ABSTRACT FROM AUTHOR]

Published
2018
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191. Continuous intraoperative neuromonitoring in thyroid surgery: Safety analysis of 400 consecutive electrode probe placements with standardized procedures

Author

Mangano, Alberto, primary, Kim, Hoon Yub, additional, Wu, Chei‐Wei, additional, Rausei, Stefano, additional, Hui, Sun, additional, Xiaoli, Liu, additional, Chiang, Feng‐Yu, additional, Roukos, Dimitrios H., additional, Lianos, Georgios D., additional, Volpi, Erivelto, additional, and Dionigi, Gianlorenzo, additional

Published
2015
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195. Surgical management of duodenal stump fistula after elective gastrectomy for malignancy: an Italian retrospective multicenter study

Author

Cozzaglio, Luca, primary, Giovenzana, Marco, additional, Biffi, Roberto, additional, Cobianchi, Lorenzo, additional, Coniglio, Arianna, additional, Framarini, Massimo, additional, Gerard, Leonardo, additional, Gianotti, Luca, additional, Marchet, Alberto, additional, Mazzaferro, Vincenzo, additional, Morgagni, Paolo, additional, Orsenigo, Elena, additional, Rausei, Stefano, additional, Romano, Fabrizio, additional, Rosa, Fausto, additional, Rosati, Riccardo, additional, Roviello, Francesco, additional, Sacchi, Matteo, additional, Morenghi, Emanuela, additional, and Quagliuolo, Vittorio, additional

Published
2014
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198. Complications after gastrectomy for cancer: Italian perspective.

Author

Baiocchi, Gian, Giacopuzzi, Simone, Marrelli, Daniele, Bencivenga, Maria, Morgagni, Paolo, Rosa, Fausto, Berselli, Mattia, Orsenigo, Elena, Cananzi, Ferdinando, Tiberio, Guido, Rausei, Stefano, Cozzaglio, Luca, Degiuli, Maurizio, Leo, Alberto, Fumagalli, Uberto, Portolani, Nazario, Rosati, Riccardo, Roviello, Franco, and Manzoni, Giovanni

Abstract

Surgery for gastric cancer is associated with significant major morbidity and an estimated mortality rate of about 5%. A reliable comparison of post-operative outcomes is hampered by the lack of a clear, universally recognized, definition of the most frequent complications. This paper reports the final results of a project launched by the Italian Research Group for Gastric Cancer in September 2015, whose goal was to propose a comprehensive list of surgical-related, gastric cancer-specific complications, with their definitions. The project was carried out through a multicentric, mainly web-based, consensus of experts. The proposed list, following assessment and validation by a group of experts of the European Chapter of the International Gastric Cancer Association, will form the basis for implementing a 'Complications Recording Sheet' that can be disseminated worldwide for proper and reliable post-operative assessment. [ABSTRACT FROM AUTHOR]

Published
2017
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