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The world is currently plagued by the Covid-19 pandemic. This situation causes the need for information as an essential thing for the public. KawalCOVID19 is one of the alternative media that contains information, education, and verification purposes regarding the Covid-19 pandemic in Indonesia, therefore good management of alternative media must be carried out by its managers. The purpose of this research is to find out how the management of KawalCOVID19 alternative media handles information about the Covid-19 pandemic. This research is a qualitative study with a descriptive method. The result of this study is that KawalCOVID19's alternative media management from the aspect of content, production, and distribution has a variety of unique features that distinguish it from mainstream media. In terms of content, KawalCOVID19 is neutral and offers a graphical display that makes it easier for readers to find out more information related to the Covid-19 pandemic. In the production aspect, the entire production process is carried out in full online collaboration of data, content, and technology teams. In the distribution aspect, KawalCOVID19 collaborates with various communities and NGOs, and uses social media to reach a wider audience. The management of KawalCOVID19 which is different from most other media, especially mainstream media during the pandemic shows that further studies are still viable regarding alternative media during the pandemic.

Pendahuluan: Periodontitis apikalis adalah peradangan dan kerusakan jaringan pada daerah apikal jaringan periodonsium. Terjadi akibat pulpa nekrosis mengalami perluasan infeksi dari bakteri saluran akar menuju apeks gigi. Penelitian terdahulu membuktikan bahwa periodontitis apikalis dapat dikaitkan dengan peningkatan kadar interleukin-6. Interleukin-6 adalah salah satu sitokin pro-inflamatori yang mempunyai peran penting dalam respon inflamasi. Tujuan penelitian menganalisis perbedaan kadar interleukin-6 dalam darah vena antara pasien dengan periodontitis apikalis dan pasien tanpa periodontitis apikalis. Metode: Jenis penelitian observasional analitik dengan dua puluh sampel stok darah vena yang terdiri atas 10 sampel darah vena pasien dengan periodontitis apikalis dan 10 sampel darah vena pasien tanpa periodontitis apikalis. Serum darah yang telah dipisahkan dengan metode sentrifugasi dipakai sebagai sampel uji enzyme-linked immunosorbent assay (ELISA) sandwich untuk mengukur kadar IL-6 dengan membaca nilai absorbansi dan kurva standar. Data yang diperoleh dianalisis menggunakan uji Shapiro-Wilk, dilanjutkan dengan uji T tidak berpasangan. Hasil: Kadar IL-6 teridentifikasi pada semua sampel. Sampel darah vena pasien tanpa periodontitis apikalis memiliki kadar IL-6 berkisar antara 4,7-18,74 mg/L, sedangkan kadar IL-6 pada pasien dengan periodontitis apikalis 4,0-90,75 mg/L. Uji T tidak berpasangan menunjukan bahwa terdapat perbedaan yang bermakna (p=0.02). Simpulan: Kadar IL-6 pada darah vena dengan periodontitis apikalis lebih tinggi dibandingkan kadar IL-6 pada tanpa periodontitis apikalis. Kata kunci: periodontitis apikalis; interleukin-6; Enzim-Linked Immunosorbent Assay Sandwich ABSTRACT Introduction: Apical periodontitis is inflammation and tissue damage in the apical area of the periodontium. Occurs due to pulp necrosis experiencing an expansion of infection from root canal bacteria to the apex of the tooth. Previous studies have shown that apical periodontitis can be associated with elevated levels of interleukin-6. Interleukin-6 is a pro-inflammatory cytokine that has a vital role in the inflammatory response. The study aimed to analyze differences in interleukin-6 levels in venous blood between patients with apical periodontitis and patients without apical periodontitis. Methods: This research was an analytic observational study with twenty venous blood samples consisting of 10 venous blood samples from patients with apical periodontitis and ten venous blood samples from patients without apical periodontitis. Blood serum that has been separated by centrifugation method was used as a sandwich enzyme-linked immunosorbent assay (ELISA) test sample to measure IL-6 levels by reading absorbance values and standard curves. The data obtained were analyzed using the Shapiro-Wilk test, followed by an unpaired T-test. Results: IL-6 levels were identified in all samples. Venous blood samples from patients without apical periodontitis had IL-6 levels ranging from 4.7-18.74 mg/L, while IL-6 levels in patients with apical periodontitis were 4.0-90.75 mg/L. The unpaired t-test showed that there was a significant difference (p=0.02). Conclusion: IL-6 levels in venous blood with apical periodontitis were higher than IL-6 levels in those without apical periodontitis. Keywords: apical periodontitis; interleukin-6; Enzyme-Linked Immunosorbent Assay Sandwich

Technology becomes a part of today’s lifestyles. Improving the quality of memorizing is significantly related to the development of learning resources through technological innovation. Educational games are one of the learning resources that can improve the memorization skills of PG/Kindergarten students. The purpose of this study was to develop an Android-based educational game as learning media and assess their effectiveness. The development model used was the ADDIE model. This research was conducted at Daar Al Husna PG/Kindergarten in Malang. Validation by material and media experts showed that the Android-based educational developed was very good and worthy of use. The effectiveness of the application of this Android-based educational game was assessed through pretest and posttest score

Environmental pollution is a global issue that occurs at this time. It is caused by various human activities that produce pollutants that endanger their lives. By utilizing current technology, it is possible to design a Water and Air Quality Monitoring System based on the Internet of Things to monitor air and water quality quickly and in real-time in the surrounding environment. The users can access this system via the web and Android / IOS mobile applications that display the data obtained by the sensor in the form of real-time graphics of water and air conditions. In addition, this system consists of several sensor nodes in charge of providing field data regarding the parameters used as the basis for assessing water and air quality according to the applicable standards in Indonesia. Sensors for water using a Turbidity Sensor, DS18B20 Sensor, PH Sensor, DHT 11, and TDS (Total Dissolved Solids) Sensor. Sensors for air consist of the DHT11 sensor, the MQ-7 sensor, the MQ-135 sensor, and the dust sensor GP2Y1010AU0F.

Identification of genetic diversity using molecular markers is important for basic information for plant conservation. Banana is a fruit bearing plants that important for food sources in human life. This study aimed to determine the optimum conditions of PCR-RAPD reaction and RAPD primers that suitable to amplify DNA fragmens. DNA isolation was done using modified of CTAB and chloroform isoamil alcohol. The samples used was young leaves of nine banana cultivar plants. Optimation was done using variety of DNA and MgCl2 concentration. Eight primers produced by Operon Primer Technology were tested. The DNA genomic concentration obtained was in the range of 23,3 ng/µl – 70 ng/µl. The optimum conditions of PCR-RAPD of banana plants that produce clear band were 50 ng/µl DNA template, 3 mM MgCl2 with the number of thermal cycles was 40 x. There were six RAPD primers that successfully amplified DNA : OPA 02, OPA 04, OPB 12, OPD 20, OPH 01, and OPH 03. The primer OPA-04 had the lowest resolving power value (4,4) , while OPH 01 had the highest (11,3) resolving power.

Objective Minimally Invasive Spinal (MIS) Procedure has long been used for treating degenerative spinal disorders, however its usage for infectious diseases of the spine has not been described a lot in literatures. Through this meta-analysis, we aim to objectively describe the efficacy of MIS as compared to traditional open surgery (OS) in treating infectious spondylodiscitis. Methods A systematic search was conducted based on PRISMA guideline to identify relevant studies through PubMed, Google Scholar, and Cochrane database. A total of 4 studies (301 patients) were included, divided into 8 meta-analysis, processed using Review Manager 5.3. Results OS requires significantly longer hospital length of stay (p=0.0009, I2=0%, MD=–6.64) and higher blood loss (p

Purpose: In order to implement Green Supply Chain Management (GSCM to support the effort in reducing the environmental impact of the supply chain processes, a framework needs to be developed. This study aimed to propose a conceptual and holistic GSCM framework to represents a roadmap towards GSCM implementation by integrating all green supply chain practices by various stakeholders of construction sector in Indonesia. Design/methodology/approach: Green practices were obtained from an extensive literature review. Questionnaire survey of GSCM stakeholders in the construction sector was conducted to obtain the preference of green supply chain variables as the proxy for variable weighting and ranking. Pairwise Comparison (PWC) and Technique for Others Preference by Similarity to Ideal (TOPSIS) were adopted to analyze the weight and to rank the green practices respectively. The finding of PWC and TOPSIS were used to develop the framework. Findings: The implementation of the GSCM in the construction sector in Indonesia is mainly focused on reducing the use of hazardous materials, the management of waste at the project site, selling products and components that are no longer used, using video conferencing both inter- and intra-organization meetings, and support from the management level in the form EMS and ISO 14001 certification. Research limitations/implications: This study did not include other GSCM performances as criteria, such as operational and logistical performance. Practical implications: An efficient evaluation technique developed by the framework can be used in decision making policies by policy makers and stakeholders of the organization which can identify and prioritize the green practices for adoption of GSCM in the construction sector Originality/value: The originality of this research is that GSCM framework was developed with most relevant green practices based on ranking and weighting criteria as well as the main stakeholders involved.

Penelitian ini bertujuan untuk menganalisis biaya subsidi dan peluang implementasi Buy the Service (BTS) untuk Bus Rapid Transit (BRT) di Kota Padang Panjang. Penelitian ini menggunakan metode kuantitatif dengan pendekatan deskriptif. Pengumpulan data primer meliputi observasi dan penyebaran kuesioner kepada responden pengguna angkutan umum dan non angkutan umum. Informasi yang diperoleh dari penyebaran kuesioner adalah asal tujuan, karakteristik perilaku angkutan umum, dan kemauan membayar masyarakat terhadap moda angkutan umum yang mengikuti standar pelayanan angkutan umum. Biaya operasional kendaraan umum diperoleh dari hasil survey biaya pokok angkutan umum yang terdiri dari biaya langsung dan tidak langsung. Hasil penelitian ini merumuskan 3 (tiga) skenario lintasan jalur utama dan analisis biaya penyelenggaraan BTS yang memenuhi Standar Pelayanan Minimal (SPM). Estimasi biaya subsidi untuk implementasi BTS di tiga koridor utama adalah 10,09 miliar, dengan biaya subsidi tertinggi berada di koridor 1 yaitu sebesar 4,41 miliar namun memiliki headway yang lebih kecil dibandingkan dua koridor lainnya. Hasil penelitian ini juga merekomendasikan perlunya sosialisasi secara terus menerus kepada masyarakat terkait kemudahan dan kenyamanan penggunaan BRT serta penyamaan persepsi antara pemerintah daerah dan operator terkait mekanisme pemberian subsidi BRT.

Recovery of mental health in people with schizophrenia spectrum disorders is essential, thus it is very important to be assessed. One instrument that measures mental health recovery is the Recovery Assessment Scale – Domains and Stages (RAS-DS), developed within the Australian cultural context to facilitate mental health recovery. An instrument based on conceptions of mental health recovery in Indonesia is still needed. This qualitative study aimed to characterise how persons with schizophrenia spectrum disorders in Indonesia define mental health recovery, to develop the Skala Pemulihan Pasien Skizofrenia (SPPS)/Indonesian Recovery Scale for Patient with Schizophrenia (I-RSPS), and to determine the content validity of the I-RSPS. Qualitative data were collected through focus group discussions (n = 11); data were analysed using conventional content analysis and thematic analysis. An inductive approach was used to develop the I-RSPS items. Content validity was evaluated using an item-level content validity index (I-CVI) and a scale-level content validity index (S-CVI). Validity evaluation trials were conducted with ten participants. Perceptions of mental health recovery in people with schizophrenia spectrum disorders in Indonesia were investigated along social, existential, clinical, functional, and physical dimensions. Some perceptions of family, religion, and spirituality are unique to the Indonesian socio-cultural context, as are some stigmas I-RSPS consists of 40 items with good content validity, with an average I-CVI of 0.99 and an average S-CVI of 0.93, and it was rated as easy to use, with 5.4 min (range: 3–10 min) being the average duration required to complete the scale.

Temperature plays a significant role in anaerobic digestion (AD) as it affects the microbial communities and ultimately controls the efficiency of the process. Few studies have looked at temperature-adjusted AD, but it is unclear how the temperature shifts affect biogas production and the dynamics of microorganisms involved in methanogenesis. This study tested two temperature shift scenarios in fed-batch mode using anaerobically digested sewage sludge and glucose-based substrate. The first scenario was acclimatized to upshifting temperatures from 42 °C to 48 °C while the second was acclimatized to downshifting temperatures from 55 °C to 45 °C. Both temperature shift scenarios resulted in a decrease in biogas production, especially at 45 °C. The upshifted scenario experienced a maximum decrease of 83%, and the downshifted scenario experienced a 16–33% decrease in methane production. Next-generation 16S rRNA sequencing revealed the domination of Methanoculleus in the upshifted scenario. However, a low correlation between the number of Methanoculleus and the other hydrogenotrophic methanogens to biogas production indicates inhibition in the hydrogenotrophic pathway. The downshifted scenario showed better biogas production due to the substantial domination of acetoclastic Methanosaeta and the low abundance of sulfate-reducing bacteria. Hence, the temperature shift affects the microbial communities, significantly affecting biogas production performance.

Latar belakang. Penelitian menunjukkan memori kerja merupakan prediktor kapasitas belajar yang lebih bermakna daripada intelligence quotient (IQ). Bila fungsi ini terganggu, anak dapat mengalami kesulitan belajar. Studi melaporkan gangguan memori kerja banyak ditemukan pada gangguan pemusatan perhatian dan hiperaktivitas (GPPH). Tujuan. Penelitian ini bertujuan untuk mendapatkan data proporsi gangguan memori kerja pada anak GPPH dan perbandingan dengan anak tanpa GPPH. Data ini diharapkan dapat menjadi data dasar bagi pengembangan intervensi selanjutnya. Metode. Penelitian ini dilakukan dengan desain potong lintang. Pengambilan sampel dilakukan dengan metode randomized sampling. Instrumen Working Memory Rating Scale (WMRS) yang telah divalidasi dalam Bahasa Indonesia oleh Wiguna, dkk. (2012) digunakan untuk menentukan ada tidaknya defisit memori kerja. Hasil. Proporsi gangguan memori kerja pada kelompok anak dengan GPPH berbeda bermakna dibandingkan kelompok anak tanpa GPPH (44% vs 0%, p

The traditional diagnosis of Attention Deficits/Hyperactivity Disorder (ADHD) is through parent-child interviews and observations; therefore, innovative ADHD diagnostic tools that represent this digital era are needed. Virtual reality (VR) is a significant technology that can present a virtual immersive environment; it can provide an illusion of participation in an artificial milieu for children with ADHD. This study aimed to develop an ADHD-VR diagnostic tool construct (Research Domain Construct/RDC) based on the DSM5 ADHD diagnostic criteria, and using the RDC to develop a diagnostic tool with a machine learning (ML) application that can produce an intelligent model to receive some complex and multifaceted clinical data (ADHD clinical symptoms). We aimed to expand a model algorithm from the data, and finally make predictions by providing new data (output data) that have more accurate diagnostic value. This was an exploratory qualitative study and consisted of two stages. The first stage of the study applied the Delphi technique, and the goal was to translate ADHD symptoms based on DSM 5 diagnostic criteria into concrete behavior that can be observed among children in a classroom setting. This stage aimed to gather information, perceptions, consensus, and confirmation from experts. In this study, three rounds of Delphi were conducted. The second stage was to finalize the RDC of the ADHD-VR diagnostic tool with ML, based on the first-stage results. The results were transformed into concrete activities that could be applied in the programming of the ADHD-VR diagnostic tool, followed by starting to input data that were required to build the diagnostic tool. The second stage consisted of more than ten focus-group discussions (FGDs) before it could be transformed into the ADHD-VR diagnostic tool with the ML prototype. First-stage data analysis was performed using Microsoft Excel for Mac. Qualitative data were analyzed using conceptual content analysis with a manifest/latent analysis approach. From the first stage of the study, there were 13 examples of student behaviors that received more than 75% totally agreed or agreed from the experts. The RDC of the ADHD-VR diagnostic tool with machine learning application consisted of three domains and was divided into six sub-domains: reward-related processing, emotional lability, inhibitory, sustained attention, specific timing of playing in order, and arousal. In conclusion, the results of this study can be used as a reference for future studies in a similar context and content, that is, the ADHD-VR diagnostic tool with machine learning based on the constructed RDC.

Objective: Clinical reasoning as an essential skill for psychiatrists, especially in forensic psychiatry, relies on their thinking and decision-making skills. However, not all psychiatrists are aware of their decision-making styles. This study examines the validity and reliability of the Indonesian translation of the Decision Style Scale (DSS) instrument among general psychiatrists in the Indonesian forensic psychiatry setting. Method: This is a cross-sectional study involving 32 general psychiatrists from all nine psychiatric residency training centers in Indonesia. The study was conducted between August 2020 and February 2021. The translation process involved certified independent translators. The validity was tested using Item-Level Content Validity Index (I-CVI), Scale-Level Level Content Validity Index (S-CVI), and item-total correlation. Internal consistency reliability was measured using Cronbach's alpha. Results: After translation, the instrument was sent back and received feedback from the original authors of DSS. The final version of DSS was valid with an I-CVI score of 0.84–1 and an S-CVI score of 0.99. All but one item had a corrected item-total correlation of more than 0.30. The reliability test of DSS also showed acceptable results with Cronbach's alpha values of 0.43–0.83, and an overall internal consistency score of 0.83 and 0.62 for intuitive and rational scales, respectively. Conclusion: DSS serves as a valid, reliable, and readily-available tool to measure psychiatrists' decision-making styles in forensic psychiatry settings. Enhancing psychiatrists’ awareness of their decision-making styles may help in mitigating the risk of bias in forensic psychiatry evaluations.

Bali is an island situated among the Indonesian archipelago with huge potential to host mangrove forests. Using remote sensing technology advances, satellite images, such as Landsat images, might be employed to analyse mangrove forest distribution and density. This paper presents an analysis of mangrove distribution in Badung Regency and Denpasar City, Bali, as a basis for the management and conservation of mangrove ecosystems. This study used Landsat 8 OLI images and a vegetation index to analyse the mangrove forest distribution and density in this area. It started by identifying mangrove forests using the RGB 564 band and continued to distinguish between mangrove and non-mangrove objects using unsupervised classification, before analysing mangrove density using the NDVI formula. The results show that the mangrove forest area in 2020 was 1,269.20 ha, with an accuracy rate of 83%. Mangroves were found on the deepest or most curved coastline of the Benoa Bay area, on enclosed waters. This distribution follows the river network in the lower reach, which has thick deposits and is uninfluenced by large currents and waves. Based on the vegetation index analysis results, the mangrove forest area observed mainly had a moderate density, with a total area of 510.85 ha (40%), followed by high density (413.15 ha/ 33%) and low density (340.51 ha/ 27%).

There are many problems related to audit quality, which are often associated with audit failures. Internal government auditors in Indonesia also have issues with audit quality. Therefore, this study aims to present empirical evidence on the relationship between independence, competence, motivation, and audit quality. It will also determine the moderating effect of time budget pressure on the relationship between factors and audit quality. Data of this study were collected through a google form, in which 57 questionnaires were sent to internal auditors of government within the Principal Inspectorate of Indonesia’s Supreme Audit Institution for at least two years. The study adopted a quantitative approach using purposive sampling. Data were analyzed using Structural Equation Modeling (SEM) with PLS version 3.0. The result findings of this study revealed that competence and motivation have a significantly positive effect on the quality of audit while independence does not. Time budget pressure does not significantly moderate such a relationship. In addition, these results have several significant implications for internal auditors as an object of consideration and evaluation relating to audits in the government sector, and information for government internal auditors to improve and maintain the quality of audit.

The Satria Agency for Social Rehabilitation of Drug Abuse Victims (BRSKPN) is a Technical Implementation Unit of the Ministry of Social Affairs of the Republic of Indonesia, which has the task of carrying out social rehabilitation for victims of drug abuse, and focuses on helping improve social roles and functions, as well as recovery of victims of drug abuse. The business processes carried out by the management of the Satria BRSKPN Office consist of viewing, editing, printing service data, administrative data, assessment data, WHOQOL data and others. There were problems that occurred in the rehabilitation process at the Satria BRSKPN Office, including the use of manual forms on paper sheets for the process of managing and documenting rehabilitation data. In this case, a rehabilitation information system is needed to improve rehabilitation services. The purpose of this research is to produce an information system for the rehabilitation of drug abuse victims. The information system is designed using the waterfall method. The waterfall method has the requirements definition stages, system and software design, implementation and unit testing, integration and system testing, and operation and maintenance. The results showed that the rehabilitation information system could be implemented in the BRSKPN Satria Office with the waterfall method that had been tested through the operation and maintenance stages. The rehabilitation information system was able to improve the management and distribution of information in order to facilitate the decision-making process at the Satria BRSKPN Office rehabilitation services.

There are lots of Nusa Dua tourism accommodation and it is interesting to be visited by domestic and foreign tourists. The author considers the need for a special portal to provide information about geography Nusa Dua tourism accommodation, in addition to this, it can also increase the interest of foreign tourists to travel with complete information without worrying. An android-based Nusa Dua tourism accommodation information system was created to provide broad information about the availability of the accommodation places in Nusa Dua. This geography information system was built using the waterfall method starting with the needs analysis, system design, coding, and testing stages. The information system built can run and function well in accordance with the needs of tourists, where the system can support tourism activities. The system is able to provide information in the form of writing, pictures and payments to increase the interest of foreign tourists visiting, especially in Nusa Dua.

Abstrak Sistem informasi rehabilitasi korban penyalahgunaan NAPZA merupakan sebuah sistem yang dibangun oleh developer systems untuk mengelola dan mendistribusikan informasi guna mempermudah pengambilan keputusan oleh pihak manajemen Kantor BRSKPN Satria. Dalam penerapan tahap awal sistem informasi rehabilitasi, pihak manajemen melakukan pengukuran guna mendapatkan feedback terhadap pengalaman pengguna sistem. Sistem ini telah digunakan selama satu bulan sebagai tahap awal penerapan. Penelitian ini menggunakan metode HEART framework untuk mengukur pengalaman pengguna dengan lima variabel, yaitu Happiness, Engagement, Adoption, Retention, dan Task Success. Hasil penelitian ini menunjukkan variabel Happiness 50% Sangat Setuju, variabel Engagement 43% Sangat Setuju, variabel Adoption 45% Sangat Setuju, variabel Retention 34% Sangat Setuju, dan Task Success 38% Sangat Setuju. Hasil menunjukkan tiga dari lima variabel HEART framework bernilai sangat setuju, yang memiliki arti sistem informasi rehabilitasi yang telah dievaluasi dapat diterima berdasarkan pengalaman pengguna. Sistem informasi rehabilitasi telah dilakukan pengukuran dan menunjukkan level usability pada kriteria “very high” dengan menggunakan Correlation Coefficient berdasarkan lima variabel HEART framework. Kata kunci: Sistem informasi, rehabilitasi, pengalaman pengguna, user experience, HEART framework Abstract The rehabilitation information system for drug abuse victims is a system developed by developer systems to manage and distribute information to facilitate decision making by the management of the Satria BRSKPN Office. In implementing the early stages of the rehabilitation information system, the management takes measurements in order to get feedback on the experience of the system users. This system has been in use for one month as an initial stage of implementation. This study uses the HEART framework method to measure user experience with five variables, namely Happiness, Engagement, Adoption, Retention, and Task Success. The results of this study indicate the variable Happiness 50% Strongly Agree, 43% Strongly Agree Engagement variable, 45% Strongly Agree Adoption variable, 34% Strongly Agree Retention variable, and 38% Strongly Agree Task Success variable. The results show that three of the five HEART framework variables are highly agree, which means that the rehabilitation information system that has been evaluated is acceptable based on user experience. The rehabilitation information system has been measured and shows the level of usability on the “very high” criteria using the Correlation Coefficient based on the five HEART framework variables. Keywords: Information systems, rehabilitation, user experience, user experience, HEART framework

Pada sepsis, endothelial glycocalyx (EG), dapat rusak dan luruh melepaskan syndecan-1 ke dalam plasma. Kerusakan EG akan mengganggu mikrosirkulasi, menimbulkan hipoperfusi jaringan, dan meningkatkan kadar laktat. Gangguan profil lipid pada sepsis terjadi karena gangguan metabolisme dan kerusakan langsung hepatosit akibat meluruhnya EG. Penelitian ini bermaksud menganalisis syndecan-1, laktat, dan profil lipid sebagai faktor risiko keparahan dan mortalitas pada pasien sepsis. Penelitian ini adalah penelitian analitik observasional pada 39 pasien dewasa yang memenuhi kritera sepsis-3. Keparahan sepsis diklasifikasikan menjadi sepsis dan syok septik dan ditentukan dalam 6 jam setelah time zero berdasarkan penggunaan vasopresor, kecukupan resusitasi cairan, dan nilai laktat ulangan. Kematian 7 hari dihitung sejak time zero sepsis. Syndecan-1, laktat, dan profil lipid diambil dalam jam pertama setelah time zero dianalisis sebagai faktor risiko keparahan dan mortalitas 7 hari. Analisis data dilakukan dengan uji logistik regresi bivariat dan multivariat. Pada penelitian ini didapatkan 20 pasien dengan sepsis, 19 pasien dengan syok septik. Berdasar atas mortalitas 7 hari, 10 pasien meninggal dan 29 pasien bertahan hidup. Laktat dan syndecan-1 merupakan prediktor keparahan pada sepsis. Laktat merupakan variabel yang lebih superior dibanding dengan syndecan-1 sebagai prediktor keparahan sepsis. Laktat merupakan prediktor untuk mortalitas 7 hari pada pasien sepsis. Simpulan penelitian ini adalah laktat dan syndecan-1 merupakan prediktor keparahan pada sepsis. Laktat merupakan prediktor kematian 7 hari pada sepsis.

In the last seven to eight years, there have been three disruptions at once: Digital Disruption, Millennial Disruption, and Pandemic Disruption. Relevant to the three disruptions which are also accompanied by changes in consumer behavior, the freight forwarding industry in Indonesia needs to transform from services product to services ecosystem. This can provide value to stakeholders in the freight forwarding industry in particular and the logistics industry in general, including transportation service providers (land, sea, air, train), warehousing, stevedoring, heavy equipment rental, custom clearance handling, banking, digital payment services, quarantine services, and the customers themselves. This study aims to gain a deeper and more understanding of Service Quality, Brand Image, and Price, in the creation of a services ecosystem in Indonesian Freight Forwarding Companies to build an orchestration of the stakeholders in the Logistics Industry. [ABSTRACT FROM AUTHOR]

The K-9 Unit of the Bali Regional Police is an elite unit specializing in using sniffer dogs to assist in various police operations, ranging from apprehending criminals and detecting narcotics, to search and rescue (SAR) operations. The ability of sniffer dogs to detect narcotics and explosives is crucial in crime prevention and control efforts. In Bali, an international tourist destination, the threat of narcotics smuggling is very high. Specially trained sniffer dogs can quickly identify the presence of these illegal substances in various locations, such as airports, seaports, and entertainment venues. This study aims to identify and analyze the role of the K-9 Unit of the Bali Regional Police in the process of crime disclosure. Through a qualitative approach with a case study method, data were collected through interviews, observations, and literature studies. Through methods of observation, interviews, and literature study, this research is expected to provide a comprehensive and in-depth overview of the role of the K-9 Unit of the Bali Regional Police. The K-9 Unit of the Bali Regional Police has a significant contribution to disclosing crimes by providing technical assistance using sniffer dogs, which have proven effective in crime scene investigation and have a direct impact on solving criminal cases. Factors affecting the effectiveness of this unit include public demand, environmental conditions, and the availability of human and animal resources. To optimize its role, it is necessary to enhance training, facilities, coordination with related parties, and regular evaluation of the unit's performance. [ABSTRACT FROM AUTHOR]

This study aimed to explore local wisdom treasures related to the study of legal culture which was not widely known by the public. This study used a mix of anthropological and juridical philosophical methods. It used the socio-legal study approach conducted through direct exploration and structured interviews. Results showed that Dayak Bakumpai indigenous people highly uphold the inclusive cultural principles contained in the Huma Betang philosophies. One of the philosophies was the resolution of mining land conflicts, influenced by the culture's positive values. This value was adopted from an inclusive culture in the Belom Bahadat values that are upheld by the Bakumpai Dayak community. Meanwhile, conflict resolution was carried out through "Bahandep Bahapakat Rakat", which is a practice of helping each other in deliberations. This is so that the headman or local traditional leader can help people return to harmony. [ABSTRACT FROM AUTHOR]

Berbagai masalah dalam proses berdemokrasi tentunya dapat berdampak terhadap berbagai aspek kehidupan berbangsa dan bernegara. Dibutuhkan penuntun yang dapat mengembalikan arah demokrasi ke arah yang seharusnya. Mengembalikannya kepada model demokrasi yang berdasarkan pada Pancasila sebagai kesepakatan luhur bangsa. Negara mempunyai suatu kewajiban dan kewenangan untuk menyelenggarakan proses demokrasi yang berbasis pada hukum dan prinsip-prinsip dasar berdemokrasi. Penting untuk mengembalikan kehidupan demokrasi berdasarkan hukum yang berbasis pada nilai-nilai Pancasila. Rumusan permasalahan dalam penelitian ini adalah apa makna Sila Keempat Pancasila dalam kehidupan demokrasi di Indonesia? dan bagaimana strategi membumikan prinsip kebijaksanaan berdasarkan Sila Keempat Pancasila dalam kehidupan demokrasi berlandaskan hukum di Indonesia ?. Penelitian ini termasuk ke dalam penelitian doktrinal yang menggunakan sumber hukum formil atau bahan hukum primer dan sumber hukum materiil atau bahan hukum sekunder. Hasil penelitian ini menunjukkan bahwa Sila Keempat Pancasila, mengandung prinsip-prinsip dasar dalam kehidupan berdemokrasi di Indonesia. Selanjutnya prinsip-prinsip tersebut tidak dapat berdiri sendiri, terpisah satu sama lain dengan prinsip-prinsip lainnya yang terkandung dalam Sila-Sila lainnya. Dalam proses berdemokrasi perlu untuk dimunculkan dan dikedepankan prinsip kebijaksanaan bagi seluruh pemangku kepentingan dalam penyelenggaraan Pemilu. Prinsip kebijaksanaan ini nampaknya menjadi prinsip yang mempunyai makna filosofi yang sangat fundamental dalam hukum yang menjadi landasan kehidupan berdemokrasi di Indonesia.

Smartphone sebagai perangkat yang sangat dibutuhkan oleh sebagian besar masyarakat saat ini, membuat semakin pesatnya aplikasi berbasis android mendorong masyarakat beralih dan menggunakan. Sistem informasi pariwisata berbasis android Wisata Brebes yang merupakan salah satu alternatif tepat dan bermanfaat untuk sarana mempermudah pengguna dalam melakukan pencarian wisata di Kabupaten Brebes secara instan. Masalah yang terjadi apakah pengguna aplikasi merasa aplikasi wisata Brebes dapat mempermudah pencarian informasi wisata Brebes. Tujuan dari penelitian ini adalah menganalisis kepuasan pengguna dalam menggunakan aplikasi Wisata Brebes menggunakan Technology Acceptance Model (TAM) dan dengan teknik pengambilan sampel yang digunakan adalah simple random sampling. Hasil pengujian analisis kepuasan pengguna menggunakan responden lokal (Brebes) maupun non lokal (luar kota) dan dianalisis dengan TAM, dalam TAM terdapat 2 pengujian uji t (partial) dan uji f (simultan), pada pengujian partial hanya variabel behavioral intention (variabel independen) yang mempunyai pengaruh terhadap variabel attitude toward using (variabel dependen) menghasilkan nilai signifikansi sebesar 0.005 < 0.05 dan nilai t-hitung 2.893 > 1.992, selanjutnya pada pengujian simultan semua variabel independen pada penelitian berpengaruh terhadap variabel dependen menghasilkan nilai signifikansi adalah 0.000 < 0.05 dan nilai f-hitung 8.343 > 2.49. Berdasarkan hasil tersebut menunjukan bahwa sistem informasi pariwisata ini memiliki pengaruh dalam membantu wisatawan mengetahui wisata yang ada dengan lebih mudah, cepat, dan efisien

Decreased limb function is one of the complications that often occurs in non-hemorrhagic stroke patients who experience hemiparesis as a result of limited joint motion in the upper and lower extremities. Acupressure is useful in improving extremity function by increasing the movement of qi (vital energy) flow in the body, but acupressure has never been done by nurses in hospital care rooms as a therapy to prevent and overcome motor function complications in non-hemorrhagic stroke patients. This study aims to identify the effect of acupressure at 14 points on the range of motion of the upper and lower extremities in non-hemorrhagic stroke patients. This study used an experimental design with a pre-post test approach design with a control group of 38 respondents (n control and n intervention = 19). The intervention group was given 14-point stroke acupressure for 15 minutes once a day for 7 days. The results showed that there were differences between the control and control ranges between the intervention group and the control group (p = 0.000). Acupressure at 14 points is an effective intervention to increase the range of motion of the upper and lower extremities in non-hemorrhagic stroke patients who have hemiparesis. The recommendation in this study is that nurses in the stroke center can apply 14-point acupressure as one of the SOPs in the treatment of non-hemorrhagic stroke patients to improve the range of motion in the extremities.

Sosial media dengan platform twitter menjadi hal menarik untuk diteliti. Trending topik tersebut menghasilkan komentar masyarakat Indonesia yang mengandung opini berupa emosi. Penelitian ini mencoba menganalisis opini di twitter dengan metode analisis vader yang menghasilkan tweet profiler kemudian visualisasi distribution. Penelitian ini menggunakan tools orange data mining dengan mengaplikasikan Prepocess text yang meliputi transformation, tokenization, normalization, dan filtering yang bertujuan agar text bisa dianalisis. Kesimpulan dari penelitian ini yaitu respon masyarakat terhadap UU Cipta Kerja Omnibus Law mendapat 6 respon dan yang paling tertinggi responnya adalah masyarakat merasa surprise.

Background and Aim: Several free-roaming dogs can be easily found in the public areas of Bali. They go out in search of foods and friends and defecate everywhere. In general, these groups of dogs do not receive good healthcare from their owners and are generally threatened by some disease-causing organisms, especially helminths. This study was conducted to identify and measure the prevalence of soil-transmitted helminths (STHs) that cause infection in free-roaming dogs in Bali Province, Indonesia. Materials and Methods: A total of 1611 fresh dog fecal samples were collected from all areas of Bali Province and subjected to qualitative fecal examination using flotation techniques to obtain STH eggs. Results: The incidence of STHs in free-roaming dogs was 38.36%. However, three types of STHs were identified, including Ancylostoma spp., Ascaris spp., and Trichuris spp. Ancylostoma spp. had the highest prevalence of 37.8%, followed by Ascaris spp. and Trichuris spp. at 6.02% and 0.87%, respectively. Multiple infections of these worms were also recorded. The polyparasitism prevalence of Ancylostoma spp. and Ascaris spp. was 3.85%, followed by that of Ancylostoma spp. and Trichuris spp. at 0.5% and that of Ascaris spp. and Trichuris spp. at 0.06%. There were no altitude-wise differences in the prevalence of STH infection. Conclusion: The prevalence of STHs was high in free-roaming dogs. This finding necessitates more serious attention as it affects both animal and public health.

Availability of Spatial Data Infrastructure (SDI) has an important role in disaster management. The purpose of this research is to analyze the readiness of the Spatial Data Infrastructure (IDS) as an effort to mitigate the lava flood in Kali Putih, Magelang Regency, Central Java. The research method was carried out by interview, survey and secondary data collection and SWOT analysis. The results of the SWOT analysis, on the Strength-Opportunity matrix, conclude that the optimization of Spatial Data Infrastructure (IDS) and the Indonesian National Standard (SNI) in the field of Geospatial Information (IG). The Strenght-Threath analysis concludes the need to use quality spatial data for government agencies. Opportunity - Weakness analysis concludes that there is a need for Web GIS development and the need to improve the quality of GI and the quality of human resources in the field of GI. Threat-Weakness analysis resulted in a conclusion, namely the need to refer to the one map and one data policy as well as the ID and SDI field policies. Ketersediaan Infrastruktur Data Spasial (SDI) memiliki peran penting dalam manajemen bencana. Tujuan penelitin ini adalah untuk menganalisis kesiapan Infrastruktur Data Spasial (IDS) sebagai upaya mitigasi banjir lahar di Kali Putih Kabupaten Magelang Jawa Tengah. Metode penelitian dilakukan dengan wawancara, survei dan pengumpulan data sekunder serta analisa SWOT. Hasil analisa SWOT, Strenght-Opportunity disimpulkan perlunya optimalisasi Infrastruktur Data Spasial (IDS) dan Standar Nasional Indonesia (SNI) bidang Informasi Geospasial (IG). Analisis Strenght-Threath menyimpulkan perlunya penggunaan data spasial yang berkualitas bagi intansi pemerintah. Analisis Opportunity – Weakness menyimpulkan bahwa perlu adanya pengembangan Web GIS dan perlunya peningkatan kualitas IG dan kualitas SDM di bidang IG. Analisis Threat-Weakness menghasilkan kesimpulan, yaitu perlunya mengacu pada kebijakan satu peta dan satu data sert kebijakan bidang ID dan SDI.

BackgroundResearch on perceived school safety has been largely limited to studies conducted in Western countries and there has been a lack of large-scale cross-national studies on the topic.MethodsThe present study examined the occurrence of adolescents who felt unsafe at school and the associated factors of perceived school safety in 13 Asian and European countries. The data were based on 21,688 adolescents aged 13-15 (11,028 girls, 10,660 boys) who completed self-administered surveys between 2011 and 2017. Logistic regression analyses were used to estimate odds ratios and 95% confidence intervals.FindingsThe number of adolescents who felt unsafe at school varied widely across countries, with a mean occurrence of 31.4% for the total sample: 31.3% for girls, and 31.1% for boys. The findings revealed strong independent associations between feeling unsafe and individual and school-related factors, such as being bullied, emotional and behavioral problems and feeling that teachers did not care. The study also found large variations in perceived school safety between schools in many countries.ConclusionThe findings emphasize the need to create safe educational environments for all students, based on positive relationships with teachers and peers. School-based interventions to prevent bullying and promote mental health should be a natural part of school safety promotion.