2,708 results on '"Xavier C"'
Search Results
152. Comparing the EMMA capnograph with sidestream capnography and arterial carbon dioxide pressure at 284 kPa.
- Author
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Vrijdag, Xavier C. E., van Waart, Hanna, Sames, Chris, Sleigh, Jamie W., and Mitchell, Simon J.
- Abstract
Introduction: Capnography aids assessment of the adequacy of mechanical patient ventilation. Physical and physiological changes in hyperbaric environments create ventilation challenges which make end-tidal carbon dioxide (ETCO2) measurement particularly important. However, obtaining accurate capnography in hyperbaric environments is widely considered difficult. This study investigated the EMMA capnograph for hyperbaric use. Methods: We compared the EMMA capnograph to sidestream capnography and the gold standard arterial carbon dioxide blood gas analysis in a hyperbaric chamber. In 12 resting subjects breathing air at 284 kPa, we recorded ETCO2 readings simultaneously derived from the EMMA and sidestream capnographs during two series of five breaths (total 24 measurements). An arterial blood gas sample was also taken simultaneously in five participants. Results: Across all measurements there was a difference of about 0.1 kPa between the EMMA and sidestream capnographs indicating a very slight over-estimation of ETCO2 by the EMMA capnograph, but fundamentally good agreement between the two end-tidal measurement methods. Compared to arterial blood gas pressure the non-significant difference was about 0.3 and 0.4 kPa for the EMMA and sidestream capnographs respectively. Conclusions: In this study, the EMMA capnograph performed equally to the sidestream capnograph when compared directly, and both capnography measures gave clinically acceptable estimates of arterial PCO2. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
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153. Full-face snorkel masks increase the incidence of hypoxaemia and hypercapnia during simulated snorkelling compared to conventional snorkels.
- Author
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Grundemann, Janneke, Vrijdag, Xavier C. E., Wong, Nicole Y. E., Gant, Nicholas, Mitchell, Simon J., and van Waart, Hanna
- Abstract
Introduction: Air flow in full-face snorkel masks (FFSMs) should be unidirectional to prevent rebreathing of exhaled air. This study evaluated rebreathing and its consequences when using FFSMs compared to a conventional snorkel. Methods: In a dry environment 20 participants wore three types of snorkel equipment in random order: Subea Easybreath FFSM; QingSong 180-degree panoramic FFSM; and a Beuchat Spy conventional snorkel (with nose clip), in three conditions: rest in a chair; light; and moderate intensity exercise on a cycle ergometer. Peripheral oxygen saturation, partial pressure of carbon dioxide (PCO2) and oxygen (PO2) in the end tidal gas and FFSM eye-pockets, respiratory rate, minute ventilation, were measured continuously. Experiments were discontinued if oxygen saturation dropped below 85%, or if end-tidal CO2 exceeded 7.0 kPa. Results: Experimental runs with the FFSMs had to be discontinued more often after exceeding 7.0 kPa end-tidal CO2 compared to a conventional snorkel e.g., 18/40 (45%) versus 4/20 (20%) during light intensity exercise, and 9/22 (41%) versus 3/16 (19%) during moderate intensity exercise. Thirteen participants exhibited peripheral oxygen saturations below 95% (nine using FFSMs and four using the conventional snorkel) and five fell below 90% (four using FFSMs and one using the conventional snorkel). The PCO2 and PO2 in the eye-pockets of the FFSMs fluctuated and were significantly higher and lower respectively than in inspired gas, which indicated rebreathing in all FFSM wearers. Conclusions: Use of FFSMs may result in rebreathing due to non-unidirectional flow, leading to hypercapnia and hypoxaemia. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
154. Operation and performance of the ATLAS Tile Calorimeter in Run 1
- Author
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Aaboud, M., Aad, G., Abbott, B., Abdallah, J., Abdinov, O., Abeloos, B., Abhayasinghe, D. K., Abidi, S. H., AbouZeid, O. S., Abraham, N. L., Abramowicz, H., Abreu, H., Abulaiti, Y., Acharya, B. S., Adachi, S., Adamczyk, L., Adelman, J., Adersberger, M., Adiguzel, A., Adye, T., Affolder, A. A., Afik, Y., Agheorghiesei, C., Aguilar-Saavedra, J. A., Ahmadov, F., Aielli, G., Akatsuka, S., Akerstedt, H., Åkesson, T. P. A., Akilli, E., Akimov, A. V., Alberghi, G. L., Albert, J., Albicocco, P., Alconada Verzini, M. J., Alderweireldt, S., Aleksa, M., Aleksandrov, I. N., Alexa, C., Alexander, G., Alexopoulos, T., Alhroob, M., Ali, B., Alimonti, G., Alison, J., Alkire, S. P., Allaire, C., Allbrooke, B. M. M., Allen, B. W., Allport, P. P., Aloisio, A., Alonso, A., Alonso, F., Alpigiani, C., Alshehri, A. A., Alstaty, M. I., Alvarez Gonzalez, B., Álvarez Piqueras, D., Alviggi, M. G., Amadio, B. T., Amaral Coutinho, Y., Ambroz, L., Amelung, C., Amidei, D., Amor Dos Santos, S. P., Amoroso, S., Amrouche, C. S., Anastopoulos, C., Ancu, L. S., Andari, N., Andeen, T., Anders, C. F., Anders, J. K., Anderson, K. J., Andreazza, A., Andrei, V., Anelli, C. R., Angelidakis, S., Angelozzi, I., Angerami, A., Anisenkov, A. V., Annovi, A., Antel, C., Anthony, M. T., Antonelli, M., Antrim, D. J. A., Anulli, F., Aoki, M., Aperio Bella, L., Arabidze, G., Arai, Y., Araque, J. P., Araujo Ferraz, V., Pereira, R. Araujo, Arce, A. T. H., Ardell, R. E., Arduh, F. A., Arguin, J.-F., Argyropoulos, S., Armbruster, A. J., Armitage, L. J., Armstrong, A., Arnaez, O., Arnold, H., Arratia, M., Arslan, O., Artamonov, A., Artoni, G., Artz, S., Asai, S., Asbah, N., Ashkenazi, A., Asimakopoulou, E. M., Asquith, L., Assamagan, K., Astalos, R., Atkin, R. J., Atkinson, M., Atlay, N. B., Auerbach, B., Augsten, K., Avolio, G., Avramidou, R., Axen, B., Ayoub, M. K., Azuelos, G., Baas, A. E., Baca, M. J., Bachacou, H., Bachas, K., Backes, M., Bagnaia, P., Bahmani, M., Bahrasemani, H., Bailey, A. J., Baines, J. T., Bajic, M., Bakalis, C., Baker, O. K., Bakker, P. J., Gupta, D. Bakshi, Baldin, E. M., Balek, P., Balli, F., Balunas, W. K., Balz, J., Banas, E., Bandyopadhyay, A., Banerjee, S., Bannoura, A. A. E., Barak, L., Barbe, W. M., Barberio, E. L., Barberis, D., Barbero, M., Barillari, T., Barisits, M-S, Barkeloo, J., Barklow, T., Barlow, N., Barnea, R., Barnes, S. L., Barnett, B. M., Barnett, R. M., Barnovska-Blenessy, Z., Baroncelli, A., Barone, G., Barr, A. J., Barranco Navarro, L., Barreiro, F., Barreiro Guimarães da Costa, J., Bartoldus, R., Barton, A. E., Bartos, P., Basalaev, A., Bassalat, A., Bates, R. L., Batista, S. J., Batlamous, S., Batley, J. R., Battaglia, M., Bauce, M., Bauer, F., Bauer, K. T., Bawa, H. S., Beacham, J. B., Beattie, M. D., Beau, T., Beauchemin, P. H., Bechtle, P., Beck, H. C., Beck, H. P., Becker, K., Becker, M., Becot, C., Beddall, A., Beddall, A. J., Bednyakov, V. A., Bedognetti, M., Bee, C. P., Beermann, T. A., Begalli, M., Begel, M., Behera, A., Behr, J. K., Bell, A. S., Bella, G., Bellagamba, L., Bellerive, A., Bellomo, M., Belotskiy, K., Belyaev, N. L., Benary, O., Benchekroun, D., Bender, M., Benekos, N., Benhammou, Y., Benhar Noccioli, E., Benitez, J., Benjamin, D. P., Benoit, M., Bensinger, J. R., Bentvelsen, S., Beresford, L., Beretta, M., Berge, D., Bergeaas Kuutmann, E., Berger, N., Bergsten, L. J., Beringer, J., Berlendis, S., Bernard, N. R., Bernardi, G., Bernius, C., Bernlochner, F. U., Berry, T., Berta, P., Bertella, C., Bertoli, G., Bertram, I. A., Besjes, G. J., Bessidskaia Bylund, O., Bessner, M., Besson, N., Bethani, A., Bethke, S., Betti, A., Bevan, A. J., Beyer, J., Bianchi, R. M., Biebel, O., Biedermann, D., Bielski, R., Bierwagen, K., Biesuz, N. V., Biglietti, M., Billoud, T. R. V., Bindi, M., Bingul, A., Bini, C., Biondi, S., Bisanz, T., Biswal, J. P., Bittrich, C., Bjergaard, D. M., Black, J. E., Black, K. M., Blair, R. E., Blazek, T., Bloch, I., Blocker, C., Blue, A., Blumenschein, U., Blunier, Dr., Bobbink, G. J., Bobrovnikov, V. S., Bocchetta, S. S., Bocci, A., Boerner, D., Bogavac, D., Bogdanchikov, A. G., Bohm, C., Boisvert, V., Bokan, P., Bold, T., Boldyrev, A. S., Bolz, A. E., Bomben, M., Bona, M., Bonilla, J. S., Boonekamp, M., Borisov, A., Borissov, G., Bortfeldt, J., Bortoletto, D., Bortolotto, V., Boscherini, D., Bosman, M., Bossio Sola, J. D., Bouaouda, K., Boudreau, J., Bouhova-Thacker, E. V., Boumediene, D., Bourdarios, C., Boutle, S. K., Boveia, A., Boyd, J., Boyko, I. R., Bozson, A. J., Bracinik, J., Brahimi, N., Brandt, A., Brandt, G., Brandt, O., Braren, F., Bratzler, U., Brau, B., Brau, J. E., Breaden Madden, W. D., Brendlinger, K., Brennan, A. J., Brenner, L., Brenner, R., Bressler, S., Brickwedde, B., Briglin, D. L., Britton, D., Britzger, D., Brock, I., Brock, R., Brooijmans, G., Brooks, T., Brooks, W. K., Brost, E., Broughton, J. H, Brown, H., Bruckman de Renstrom, P. A., Bruncko, D., Bruni, A., Bruni, G., Bruni, L. S., Bruno, S., Brunt, B. H., Bruschi, M., Bruscino, N., Bryant, P., Bryngemark, L., Buanes, T., Buat, Q., Buchholz, P., Buckley, A. G., Budagov, I. A., Bugge, M. K., Bührer, F., Bulekov, O., Bullock, D., Burch, T. J., Burdin, S., Burgard, C. D., Burger, A. M., Burghgrave, B., Burka, K., Burke, S., Burmeister, I., Burr, J. T. P., Busato, E., Büscher, D., Büscher, V., Buschmann, E., Bussey, P., Butler, J. M., Buttar, C. M., Butterworth, J. M., Butti, P., Buttinger, W., Buzatu, A., Buzykaev, A. R., Cabras, G., Cabrera Urbán, S., Caforio, D., Cai, H., Cairo, V. M. M., Cakir, O., Calace, N., Calafiura, P., Calandri, A., Calderini, G., Calfayan, P., Callea, G., Caloba, L. P., Calvente Lopez, S., Calvet, D., Calvet, S., Calvet, T. P., Calvetti, M., Camacho Toro, R., Camarda, S., Camarri, P., Cameron, D., Caminal Armadans, R., Camincher, C., Campana, S., Campanelli, M., Camplani, A., Campoverde, A., Canale, V., Cano Bret, M., Cantero, J., Cao, T., Cao, Y., Capeans Garrido, M. D. M., Caprini, I., Caprini, M., Capua, M., Carbone, R. M., Cardarelli, R., Cardillo, F. C., Carli, I., Carli, T., Carlino, G., Carlson, B. T., Carminati, L., Carney, R. M. D., Caron, S., Carquin, E., Carrá, S., Carrillo-Montoya, G. D., Argos, F. Carrio, Casadei, D., Casado, M. P., Casha, A. F., Casolino, M., Casper, D. W., Castelijn, R., Castillo, F. L., Castillo Gimenez, V., Castro, N. F., Catinaccio, A., Catmore, J. R., Cattai, A., Caudron, J., Cavaliere, V., Cavallaro, E., Cavalli, D., Cavalli-Sforza, M., Cavasinni, V., Celebi, E., Ceradini, F., Cerda Alberich, L., Cerqueira, A. S., Cerri, A., Cerrito, L., Cerutti, F., Cervelli, A., Cetin, S. A., Chafaq, A., Chakraborty, D., Chan, S. K., Chan, W. S., Chan, Y. L., Chang, P., Chapman, J. D., Charlton, D. G., Chau, C. C., Chavez Barajas, C. A., Che, S., Chegwidden, A., Chekanov, S., Chekulaev, S. V., Chelkov, G. A., Chelstowska, M. A., Chen, C., Chen, C. H., Chen, H., Chen, J., Chen, J., Chen, S., Chen, S. J., Chen, X., Chen, Y., Chen, Y-H., Cheng, H. C., Cheng, H. J., Cheplakov, A., Cheremushkina, E., Cherkaoui El Moursli, R., Cheu, E., Cheung, K., Chevalier, L., Chiarella, V., Chiarelli, G., Chiodini, G., Chisholm, A. S., Chitan, A., Chiu, I., Chiu, Y. H., Chizhov, M. V., Choi, K., Chomont, A. R., Chouridou, S., Chow, Y. S., Christodoulou, V., Chu, M. C., Chudoba, J., Chuinard, A. J., Chwastowski, J. J., Chytka, L., Cinca, D., Cindro, V., Cioară, I. A., Ciocio, A., Xavier, C. T. Ciodaro, Cirotto, F., Citron, Z. H., Citterio, M., Clark, A., Clark, M. R., Clark, P. J., Clement, C., Coadou, Y., Cobal, M., Coccaro, A., Cochran, J., Coimbra, A. E. C., Colasurdo, L., Cole, B., Colijn, A. P., Collot, J., Conde Muiño, P., Coniavitis, E., Connell, S. H., Connelly, I. A., Constantinescu, S., Conventi, F., Cooper-Sarkar, A. M., Cormier, F., Cormier, K. J. R., Corradi, M., Corrigan, E. E., Corriveau, F., Cortes-Gonzalez, A., Costa, M. J., Costanzo, D., Cottin, G., Cowan, G., Cox, B. E., Crane, J., Cranmer, K., Crawley, S. J., Creager, R. A., Cree, G., Crépé-Renaudin, S., Crescioli, F., Cristinziani, M., Croft, V., Crosetti, G., Cueto, A., Cuhadar Donszelmann, T., Cukierman, A. R., Curatolo, M., Cúth, J., Czekierda, S., Czodrowski, P., Da Cunha Sargedas De Sousa, M. J., Da Via, C., Dabrowski, W., Dado, T., Dahbi, S., Dai, T., Dallaire, F., Dallapiccola, C., Dam, M., D’amen, G., Damp, J., Dandoy, J. R., Daneri, M. F., Dang, N. P., Dann, N. D., Danninger, M., Dao, V., Darbo, G., Darmora, S., Dartsi, O., Dattagupta, A., Daubney, T., D’Auria, S., Davey, W., David, C., Davidek, T., Davis, D. R., Davydov, Y., Dawe, E., Dawson, I., De, K., De Asmundis, R., De Benedetti, A., De Castro, S., De Cecco, S., De Groot, N., de Jong, P., De la Torre, H., De Lorenzi, F., De Maria, A., De Pedis, D., De Salvo, A., De Sanctis, U., De Santo, A., De Vasconcelos Corga, K., De Vivie De Regie, J. B., Debenedetti, C., Dedovich, D. V., Dehghanian, N., Del Gaudio, M., Del Peso, J., Delgove, D., Deliot, F., Delitzsch, C. M., Della Pietra, M., Della Volpe, D., Dell’Acqua, A., Dell’Asta, L., Delmastro, M., Delporte, C., Delsart, P. A., DeMarco, D. A., Demers, S., Demichev, M., Denisov, S. P., Denysiuk, D., D’Eramo, L., Derendarz, D., Derkaoui, J. E., Derue, F., Dervan, P., Desch, K., Deterre, C., Dette, K., Devesa, M. R., Deviveiros, P. O., Dewhurst, A., Dhaliwal, S., Di Bello, F. A., Di Ciaccio, A., Di Ciaccio, L., Di Clemente, W. K., Di Donato, C., Di Girolamo, A., Di Micco, B., Di Nardo, R., Di Petrillo, K. F., Di Simone, A., Di Sipio, R., Di Valentino, D., Diaconu, C., Diamond, M., Dias, F. A., Dias Do Vale, T., Diaz, M. A., Dickinson, J., Diehl, E. B., Dietrich, J., Díez Cornell, S., Dimitrievska, A., Dingfelder, J., Dittus, F., Djama, F., Djobava, T., Djuvsland, J. I., Do Vale, M. A. B., Dobre, M., Dodsworth, D., Doglioni, C., Dolejsi, J., Dolezal, Z., Donadelli, M., Donini, J., D’onofrio, A., D’Onofrio, M., Dopke, J., Doria, A., Dova, M. T., Doyle, A. T., Drechsler, E., Dreyer, E., Dreyer, T., Dris, M., Du, Y., Duarte-Campderros, J., Dubinin, F., Dubreuil, A., Duchovni, E., Duckeck, G., Ducourthial, A., Ducu, O. A., Duda, D., Dudarev, A., Dudder, A. C., Duffield, E. M., Duflot, L., Dührssen, M., Dülsen, C., Dumancic, M., Dumitriu, A. E., Duncan, A. K., Dunford, M., Duperrin, A., Duran Yildiz, H., Düren, M., Durglishvili, A., Duschinger, D., Dutta, B., Duvnjak, D., Dyndal, M., Dysch, S., Dziedzic, B. S., Eckardt, C., Ecker, K. M., Edgar, R. C., Eifert, T., Eigen, G., Einsweiler, K., Ekelof, T., El Kacimi, M., El Kosseifi, R., Ellajosyula, V., Ellert, M., Ellinghaus, F., Elliot, A. A., Ellis, N., Elmsheuser, J., Elsing, M., Emeliyanov, D., Enari, Y., Ennis, J. S., Epland, M. B., Erdmann, J., Ereditato, A., Errede, S., Escalier, M., Escobar, C., Esposito, B., Estrada Pastor, O., Etienvre, A. I., Etzion, E., Evans, H., Ezhilov, A., Ezzi, M., Fabbri, F., Fabbri, L., Fabiani, V., Facini, G., Faisca Rodrigues Pereira, R. M., Fakhrutdinov, R. M., Falciano, S., Falke, P. J., Falke, S., Faltova, J., Fang, Y., Fanti, M., Farbin, A., Farilla, A., Farina, E. M., Farooque, T., Farrell, S., Farrington, S. M., Farthouat, P., Fassi, F., Fassnacht, P., Fassouliotis, D., Faucci Giannelli, M., Favareto, A., Fawcett, W. J., Fayard, L., Fedin, O. L., Fedorko, W., Feickert, M., Feigl, S., Feligioni, L., Feng, C., Feng, E. J., Feng, M., Fenton, M. J., Fenyuk, A. B., Feremenga, L., Ferrando, J., Ferrari, A., Ferrari, P., Ferrari, R., Ferreira de Lima, D. E., Ferrer, A., Ferrere, D., Ferretti, C., Fiedler, F., Filipčič, A., Filthaut, F., Finelli, K. D., Fiolhais, M. C. N., Fiorini, L., Fischer, C., Fisher, W. C., Flaschel, N., Fleck, I., Fleischmann, P., Fletcher, R. R. M., Flick, T., Flierl, B. M., Flores, L. M., Flores Castillo, L. R., Fomin, N., Forcolin, G. T., Formica, A., Förster, F. A., Forti, A. C., Foster, A. G., Fournier, D., Fox, H., Fracchia, S., Francavilla, P., Franchini, M., Franchino, S., Francis, D., Franconi, L., Franklin, M., Frate, M., Fraternali, M., Freeborn, D., Fressard-Batraneanu, S. M., Freund, B., Freund, W. S., Froidevaux, D., Frost, J. A., Fukunaga, C., Fusayasu, T., Fuster, J., Gabizon, O., Gabrielli, A., Gabrielli, A., Gach, G. P., Gadatsch, S., Gadow, P., Gagliardi, G., Gagnon, L. G., Galea, C., Galhardo, B., Gallas, E. J., Gallop, B. J., Gallus, P., Galster, G., Gamboa Goni, R., Gan, K. K., Ganguly, S., Gao, Y., Gao, Y. S., García, C., García Navarro, J. E., García Pascual, J. A., Garcia-Sciveres, M., Gardner, R. W., Garelli, N., Garonne, V., Gasnikova, K., Gaudiello, A., Gaudio, G., Gavrilenko, I. L., Gavrilyuk, A., Gay, C., Gaycken, G., Gazis, E. N., Gee, C. N. P., Geisen, J., Geisen, M., Geisler, M. P., Gellerstedt, K., Gemme, C., Genest, M. H., Geng, C., Gentile, S., Gentsos, C., George, S., Gerbaudo, D., Gessner, G., Ghasemi, S., Ghasemi Bostanabad, M., Ghneimat, M., Giacobbe, B., Giagu, S., Giangiacomi, N., Giannetti, P., Gibson, S. M., Gignac, M., Gillberg, D., Gilles, G., Gingrich, D. M., Giordani, M. P., Giorgi, F. M., Giraud, P. F., Giromini, P., Giugliarelli, G., Giugni, D., Giuli, F., Giulini, M., Gkaitatzis, S., Gkialas, I., Gkougkousis, E. L., Gkountoumis, P., Gladilin, L. K., Glasman, C., Glatzer, J., Glaysher, P. C. F., Glazov, A., Goblirsch-Kolb, M., Godlewski, J., Goldfarb, S., Golling, T., Golubkov, D., Gomes, A., Goncalves Gama, R., Gonçalo, R., Gonella, G., Gonella, L., Gongadze, A., Gonnella, F., Gonski, J. L., González de la Hoz, S., Gonzalez Parra, G., Gonzalez-Sevilla, S., Goossens, L., Gorbounov, P. A., Gordon, H. A., Gorini, B., Gorini, E., Gorišek, A., Goshaw, A. T., Gössling, C., Gostkin, M. I., Gottardo, C. A., Goudet, C. R., Goujdami, D., Goussiou, A. G., Govender, N., Goy, C., Gozani, E., Grabowska-Bold, I., Gradin, P. O. J., Graham, E. C., Gramling, J., Gramstad, E., Grancagnolo, S., Gratchev, V., Gravila, P. M., Gray, C., Gray, H. M., Greenwood, Z. D., Grefe, C., Gregersen, K., Gregor, I. M., Grenier, P., Grevtsov, K., Griffiths, J., Grillo, A. A., Grimm, K., Grinstein, S., Gris, Ph., Grivaz, J.-F., Groh, S., Gross, E., Grosse-Knetter, J., Grossi, G. C., Grout, Z. J., Grud, C., Grummer, A., Guan, L., Guan, W., Guenther, J., Guerguichon, A., Guescini, F., Guest, D., Gugel, R., Gui, B., Guillemin, T., Guindon, S., Gul, U., Gumpert, C., Guo, J., Guo, W., Guo, Y., Guo, Z., Gupta, R., Gurbuz, S., Gurriana, L., Gustavino, G., Gutelman, B. J., Gutierrez, P., Gutschow, C., Guyot, C., Guzik, M. P., Gwenlan, C., Gwilliam, C. B., Haas, A., Haber, C., Hadavand, H. K., Haddad, N., Hadef, A., Hageböck, S., Hagihara, M., Hakobyan, H., Haleem, M., Haley, J., Halladjian, G., Hallewell, G. D., Hamacher, K., Hamal, P., Hamano, K., Hamilton, A., Hamity, G. N., Han, K., Han, L., Han, S., Hanagaki, K., Hance, M., Handl, D. M., Haney, B., Hankache, R., Hanke, P., Hansen, E., Hansen, J. B., Hansen, J. D., Hansen, M. C., Hansen, P. H., Hara, K., Hard, A. S., Harenberg, T., Harkusha, S., Harrison, P. F., Hartmann, N. M., Hasegawa, Y., Hasib, A., Hassani, S., Haug, S., Hauser, R., Hauswald, L., Havener, L. B., Havranek, M., Hawkes, C. M., Hawkings, R. J., Hayden, D., Hayes, C., Hays, C. P., Hays, J. M., Hayward, H. S., Haywood, S. J., Heath, M. P., Hedberg, V., Heelan, L., Heer, S., Heidegger, K. K., Heilman, J., Heim, S., Heim, T., Heinemann, B., Heinrich, J. J., Heinrich, L., Heinz, C., Hejbal, J., Helary, L., Held, A., Hellesund, S., Hellman, S., Helsens, C., Henderson, R. C. W., Heng, Y., Henkelmann, S., Henriques Correia, A. M., Herbert, G. H., Herde, H., Herget, V., Hernandez, C. M., Hernández Jiménez, Y., Herr, H., Herten, G., Hertenberger, R., Hervas, L., Herwig, T. C., Hesketh, G. G., Hessey, N. P., Hetherly, J. W., Higashino, S., Higón-Rodriguez, E., Hildebrand, K., Hill, E., Hill, J. C., Hill, K. K., Hiller, K. H., Hillier, S. J., Hils, M., Hinchliffe, I., Hirose, M., Hirschbuehl, D., Hiti, B., Hladik, O., Hlaluku, D. R., Hoad, X., Hobbs, J., Hod, N., Hodgkinson, M. C., Hoecker, A., Hoeferkamp, M. R., Hoenig, F., Hohn, D., Hohov, D., Holmes, T. R., Holzbock, M., Homann, M., Honda, S., Honda, T., Hong, T. 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C., Rizatdinova, F., Rizvi, E., Rizzi, C., Roberts, R. T., Robertson, S. H., Robichaud-Veronneau, A., Robinson, D., Robinson, J. E. M., Robson, A., Rocco, E., Roda, C., Rodina, Y., Rodriguez Bosca, S., Rodriguez Perez, A., Rodriguez Rodriguez, D., Rodríguez Vera, A. M., Roe, S., Rogan, C. S., Røhne, O., Röhrig, R., Roland, C. P. A., Roloff, J., Romaniouk, A., Romano, M., Rompotis, N., Ronzani, M., Roos, L., Rosati, S., Rosbach, K., Rose, P., Rosien, N-A., Rossetti, V., Rossi, E., Rossi, L. P., Rossini, L., Rosten, J. H. N., Rosten, R., Rotaru, M., Rothberg, J., Rousseau, D., Roy, D., Rozanov, A., Rozen, Y., Ruan, X., Rubbo, F., Rühr, F., Ruiz-Martinez, A., Rurikova, Z., Rusakovich, N. A., Russell, H. L., Rutherfoord, J. P., Ruthmann, N., Rüttinger, E. M., Ryabov, Y. F., Rybar, M., Rybkin, G., Ryu, S., Ryzhov, A., Rzehorz, G. F., Sabatini, P., Sabato, G., Sacerdoti, S., Sadrozinski, H. F-W., Sadykov, R., Safai Tehrani, F., Saha, P., Sahinsoy, M., Sahu, A., Sahu, S., Saimpert, M., Saito, M., Saito, T., Sakamoto, H., Sakharov, A., Salamani, D., Salamanna, G., Salazar Loyola, J. E., Salek, D., Sales De Bruin, P. H., Salihagic, D., Salnikov, A., Salt, J., Salvatore, D., Salvatore, F., Salvucci, A., Salzburger, A., Sammel, D., Sampsonidis, D., Sampsonidou, D., Sánchez, J., Sanchez Pineda, A., Sandaker, H., Sander, C. O., Sanders, H., Sandhoff, M., Sandoval, C., Sankey, D. P. C., Sannino, M., Sano, Y., Sansoni, A., Santoni, C., Santos, H., Santoyo Castillo, I., Sapronov, A., Saraiva, J. G., Sargsyan, L, Sasaki, O., Sato, K., Sauvan, E., Savard, P., Savic, N., Sawada, R., Sawyer, C., Sawyer, L., Says, L. P., Sbarra, C., Sbrizzi, A., Scanlon, T., Schaarschmidt, J., Schacht, P., Schachtner, B. M., Schaefer, D., Schaefer, L., Schaeffer, J., Schaepe, S., Schäfer, U., Schaffer, A. C., Schaile, D., Schamberger, R. D., Scharmberg, N., Schegelsky, V. A., Scheirich, D., Schenck, F., Schernau, M., Schiavi, C., Schier, S., Schildgen, L. K., Schillaci, Z. M., Schioppa, E. J., Schioppa, M., Schleicher, K. E., Schlenker, S., Schmidt-Sommerfeld, K. R., Schmieden, K., Schmitt, C., Schmitt, S., Schmitz, S., Schnoor, U., Schoeffel, L., Schoening, A., Schopf, E., Schott, M., Schouwenberg, J. F. P., Schovancova, J., Schramm, S., Schulte, A., Schultz-Coulon, H-C., Schumacher, M., Schumm, B. A., Schune, Ph., Schwartzman, A., Schwarz, T. A., Schweiger, H., Schwemling, Ph., Schwienhorst, R., Sciandra, A., Sciolla, G., Scornajenghi, M., Scuri, F., Scutti, F., Scyboz, L. M., Searcy, J., Sebastiani, C. D., Seema, P., Seidel, S. C., Seiden, A., Seiss, T., Seixas, J. M., Sekhniaidze, G., Sekhon, K., Sekula, S. J., Semprini-Cesari, N., Sen, S., Senkin, S., Serfon, C., Serin, L., Serkin, L., Sessa, M., Severini, H., Sforza, F., Sfyrla, A., Shabalina, E., Shahinian, J. D., Shaikh, N. W., Shalyugin, A., Shan, L. Y., Shang, R., Shank, J. T., Shapiro, M., Sharma, A. S., Sharma, A., Shatalov, P. B., Shaw, K., Shaw, S. M., Shcherbakova, A., Shen, Y., Sherafati, N., Sherman, A. D., Sherwood, P., Shi, L., Shimizu, S., Shimmin, C. O., Shimojima, M., Shipsey, I. P. J., Shirabe, S., Shiyakova, M., Shlomi, J., Shmeleva, A., Shoaleh Saadi, D., Shochet, M. J., Shojaii, S., Shope, D. R., Shrestha, S., Shulga, E., Sicho, P., Sickles, A. M., Sidebo, P. E., Sideras Haddad, E., Sidiropoulou, O., Sidoti, A., Siegert, F., Sijacki, Dj., Silva, J., Silva, Jr., M., Silverstein, S. B., Simic, L., Simion, S., Simioni, E., Simon, M., Sinervo, P., Sinev, N. B., Sioli, M., Siragusa, G., Siral, I., Sivoklokov, S. Yu., Gomes, A. Sivolella, Sjölin, J., Skinner, M. B., Skubic, P., Slater, M., Slavicek, T., Slawinska, M., Sliwa, K., Slovak, R., Smakhtin, V., Smart, B. H., Smiesko, J., Smirnov, N., Smirnov, S. Yu., Smirnov, Y., Smirnova, L. N., Smirnova, O., Smith, J. W., Smith, M. N. K., Smith, R. W., Smizanska, M., Smolek, K., Snesarev, A. A., Snyder, I. M., Snyder, S., Sobie, R., Soffa, A. M., Soffer, A., Søgaard, A., Soh, D. A., Sokhrannyi, G., Solans Sanchez, C. A., Solar, M., Soldatov, E. Yu., Soldevila, U., Solin, A., Solodkov, A. A., Soloshenko, A., Solovyanov, O. V., Solovyev, V., Sommer, P., Son, H., Song, W., Sopczak, A., Sopkova, F., Sosa, D., Sotiropoulou, C. L., Sottocornola, S., Soualah, R., Soukharev, A. M., South, D., Sowden, B. C., Spagnolo, S., Spalla, M., Spangenberg, M., Spanò, F., Sperlich, D., Spettel, F., Spieker, T. M., Spighi, R., Spigo, G., Spiller, L. A., Spiteri, D. P., Spousta, M., Stabile, A., Stamen, R., Stamm, S., Stanecka, E., Stanek, R. W., Stanescu, C., Stanitzki, M. M., Stapf, B., Stapnes, S., Starchenko, E. A., Stark, G. H., Stark, J., Stark, S. H, Staroba, P., Starovoitov, P., Stärz, S., Staszewski, R., Stegler, M., Steinberg, P., Stelzer, B., Stelzer, H. J., Stelzer-Chilton, O., Stenzel, H., Stevenson, T. J., Stewart, G. A., Stockton, M. C., Stoicea, G., Stolte, P., Stonjek, S., Straessner, A., Strandberg, J., Strandberg, S., Strauss, M., Strizenec, P., Ströhmer, R., Strom, D. M., Stroynowski, R., Strubig, A., Stucci, S. A., Stugu, B., Stupak, J., Styles, N. A., Su, D., Su, J., Suchek, S., Sugaya, Y., Suk, M., Sulin, V. V., Sultan, D. M. S., Sultansoy, S., Sumida, T., Sun, S., Sun, X., Suruliz, K., Suster, C. J. E., Sutton, M. R., Suzuki, S., Svatos, M., Swiatlowski, M., Swift, S. P., Sydorenko, A., Sykora, I., Sykora, T., Ta, D., Tackmann, K., Taenzer, J., Taffard, A., Tafirout, R., Tahirovic, E., Taiblum, N., Takai, H., Takashima, R., Takasugi, E. H., Takeda, K., Takeshita, T., Takubo, Y., Talby, M., Talyshev, A. A., Tanaka, J., Tanaka, M., Tanaka, R., Tang, F., Tanioka, R., Tannenwald, B. B., Tapia Araya, S., Tapprogge, S., Tarek Abouelfadl Mohamed, A., Tarem, S., Tarna, G., Tartarelli, G. F., Tas, P., Tasevsky, M., Tashiro, T., Tassi, E., Tavares Delgado, A., Tayalati, Y., Taylor, A. C., Taylor, A. J., Taylor, G. N., Taylor, P. T. E., Taylor, W., Tee, A. S., Teixeira-Dias, P., Temple, D., Ten Kate, H., Teng, P. K., Teoh, J. J., Tepel, F., Terada, S., Terashi, K., Terron, J., Terzo, S., Testa, M., Teuscher, R. J., Thais, S. J., Theveneaux-Pelzer, T., Thiele, F., Thomas, J. P., Thompson, A. S., Thompson, P. D., Thomsen, L. A., Thomson, E., Tian, Y., Ticse Torres, R. E., Tikhomirov, V. O., Tikhonov, Yu. A., Timoshenko, S., Tipton, P., Tisserant, S., Todome, K., Todorova-Nova, S., Todt, S., Tojo, J., Tokár, S., Tokushuku, K., Tolley, E., Tomiwa, K. G., Tomoto, M., Tompkins, L., Toms, K., Tong, B., Tornambe, P., Torrence, E., Torres, H., Torró Pastor, E., Tosciri, C., Toth, J., Touchard, F., Tovey, D. R., Treado, C. J., Trefzger, T., Tresoldi, F., Tricoli, A., Trigger, I. M., Trincaz-Duvoid, S., Tripiana, M. F., Trischuk, W., Trocmé, B., Trofymov, A., Troncon, C., Trovatelli, M., Trovato, F., Truong, L., Trzebinski, M., Trzupek, A., Tsai, F., Tseng, J. C-L., Tsiareshka, P. V., Tsirintanis, N., Tsiskaridze, V., Tskhadadze, E. G., Tsukerman, I. I., Tsulaia, V., Tsuno, S., Tsybychev, D., Tu, Y., Tudorache, A., Tudorache, V., Tulbure, T. T., Tuna, A. N., Turchikhin, S., Turgeman, D., Turk Cakir, I., Turra, R., Tuts, P. M., Tylmad, M., Tzovara, E., Ucchielli, G., Ueda, I., Ughetto, M., Ukegawa, F., Unal, G., Undrus, A., Unel, G., Ungaro, F. C., Unno, Y., Uno, K., Urban, J., Urquijo, P., Urrejola, P., Usai, G., Usui, J., Vacavant, L., Vacek, V., Vachon, B., Vadla, K. O. H., Vaidya, A., Valderanis, C., Valdes Santurio, E., Valente, M., Valentinetti, S., Valero, A., Valéry, L., Vallance, R. A., Vallier, A., Valls Ferrer, J. A., Van Daalen, T. R., Van Den Wollenberg, W., Van der Graaf, H., Van Gemmeren, P., Van Nieuwkoop, J., Van Vulpen, I., van Woerden, M. C., Vanadia, M., Vandelli, W., Vaniachine, A., Vankov, P., Vari, R., Varnes, E. W., Varni, C., Varol, T., Varouchas, D., Vartapetian, A., Varvell, K. E., Vasquez, G. A., Vasquez, J. G., Vazeille, F., Vazquez Furelos, D., Vazquez Schroeder, T., Veatch, J., Vecchio, V., Veloce, L. M., Veloso, F., Veneziano, S., Ventura, A., Venturi, M., Venturi, N., Vercesi, V., Verducci, M., Infante, C. M. Vergel, Verkerke, W., Vermeulen, A. T., Vermeulen, J. C., Vetterli, M. C., Viaux Maira, N., Viazlo, O., Vichou, I., Vickey, T., Vickey Boeriu, O. E., Viehhauser, G. H. A., Viel, S., Vigani, L., Villa, M., Villaplana Perez, M., Vilucchi, E., Vincter, M. G., Vinogradov, V. B., Viret, S., Vishwakarma, A., Vittori, C., Vivarelli, I., Vlachos, S., Vogel, M., Vokac, P., Volpi, G., Volpi, M., von Buddenbrock, S. E., Von Toerne, E., Vorobel, V., Vorobev, K., Vos, M., Vossebeld, J. H., Vranjes, N., Vranjes Milosavljevic, M., Vrba, V., Vreeswijk, M., Šfiligoj, T., Vuillermet, R., Vukotic, I., Ženiš, T., Živković, L., Wagner, P., Wagner, W., Wagner-Kuhr, J., Wahlberg, H., Wahrmund, S., Wakamiya, K., Walbrecht, V. M., Walder, J., Walker, R., Walkowiak, W., Wallangen, V., Wang, A. M., Wang, C., Wang, F., Wang, H., Wang, H., Wang, J., Wang, J., Wang, P., Wang, Q., Wang, R.-J., Wang, R., Wang, R., Wang, S. M., Wang, W. T., Wang, W., Wang, W. X., Wang, Y., Wang, Z., Wanotayaroj, C., Warburton, A., Ward, C. P., Wardrope, D. R., Washbrook, A., Watkins, P. M., Watson, A. T., Watson, M. F., Watts, G., Watts, S., Waugh, B. M., Weatherly, P., Webb, A. F., Webb, S., Weber, C., Weber, M. S., Weber, S. A., Weber, S. M., Webster, J. S., Weidberg, A. R., Weinert, B., Weingarten, J., Weirich, M., Weiser, C., Wells, P. S., Wenaus, T., Wengler, T., Wenig, S., Wermes, N., Werner, M. D., Werner, P., Wessels, M., Weston, T. D., Whalen, K., Whallon, N. L., Wharton, A. M., White, A. S., White, A., White, M. J., White, R., Whiteson, D., Whitmore, B. W., Wickens, F. J., Wiedenmann, W., Wielers, M., Wiglesworth, C., Wiik-Fuchs, L. A. M., Wildauer, A., Wilk, F., Wilkens, H. G., Wilkins, L. J., Williams, H. H., Williams, S., Willis, C., Willocq, S., Wilson, J. A., Wingerter-Seez, I., Winkels, E., Winklmeier, F., Winston, O. J., Winter, B. T., Wittgen, M., Wobisch, M., Wolf, A., Wolf, T. M. H., Wolff, R., Wolter, M. W., Wolters, H., Wong, V. W. S., Woods, N. L., Worm, S. D., Wosiek, B. K., Woźniak, K. W., Wraight, K., Wu, M., Wu, S. L., Wu, X., Wu, Y., Wyatt, T. R., Wynne, B. M., Xella, S., Xi, Z., Xia, L., Xu, D., Xu, H., Xu, L., Xu, T., Xu, W., Yabsley, B., Yacoob, S., Yajima, K., Yallup, D. P., Yamaguchi, D., Yamaguchi, Y., Yamamoto, A., Yamanaka, T., Yamane, F., Yamatani, M., Yamazaki, T., Yamazaki, Y., Yan, Z., Yang, H. J., Yang, H. T., Yang, S., Yang, Y., Yang, Z., Yao, W-M., Yap, Y. C., Yasu, Y., Yatsenko, E., Ye, J., Ye, S., Yeletskikh, I., Yigitbasi, E., Yildirim, E., Yorita, K., Yoshihara, K., Young, C. J. S., Young, C., Yu, J., Yu, J., Yue, X., Yuen, S. P. Y., Yusuff, I., Zabinski, B., Zacharis, G., Zaffaroni, E., Zaidan, R., Zaitsev, A. M., Zakharchuk, N., Zalieckas, J., Zambito, S., Zanzi, D., Zaripovas, D. R., Zeißner, S. V., Zeitnitz, C., Zemaityte, G., Zeng, J. C., Zeng, Q., Zenin, O., Zerwas, D., Zgubič, M., Zhang, D. F., Zhang, D., Zhang, F., Zhang, G., Zhang, H., Zhang, J., Zhang, L., Zhang, L., Zhang, M., Zhang, P., Zhang, R., Zhang, R., Zhang, X., Zhang, Y., Zhang, Z., Zhao, P., Zhao, X., Zhao, Y., Zhao, Z., Zhemchugov, A., Zhou, B., Zhou, C., Zhou, L., Zhou, M. S., Zhou, M., Zhou, N., Zhou, Y., Zhu, C. G., Zhu, H. L., Zhu, H., Zhu, J., Zhu, Y., Zhuang, X., Zhukov, K., Zhulanov, V., Zibell, A., Zieminska, D., Zimine, N. I., Zimmermann, S., Zinonos, Z., Zinser, M., Ziolkowski, M., Zobernig, G., Zoccoli, A., Zoch, K., Zorbas, T. G., Zou, R., Zur Nedden, M., Zwalinski, L., and ATLAS Collaboration
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- 2018
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155. A 35-bp Conserved Region Is Crucial for
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Xavier C, Giner, Kenley Joule, Pierre, Nicholas M, Robert, and Jacques J, Tremblay
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The peptide hormone insulin-like 3 (INSL3) is produced almost exclusively by Leydig cells of the male gonad. INSL3 has several functions such as fetal testis descent and bone metabolism in adults.
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- 2022
156. Weight Stigma and Avoidance of Physical Activity and Sport: Development of a Scale and Establishment of Correlates
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Nadia Bevan, Kerry S. O’Brien, Janet D. Latner, Chung-Ying Lin, Brian Vandenberg, Ruth Jeanes, and Xavier C. C. Fung
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Adult ,physical activity ,avoidance ,participation ,scale development ,weight stigma ,Young Adult ,Weight Prejudice ,Health, Toxicology and Mutagenesis ,Surveys and Questionnaires ,Public Health, Environmental and Occupational Health ,Humans ,Reproducibility of Results ,Exercise ,Sports - Abstract
Participation in sport and physical activity (PA) is declining, and the psychosocial factors underpinning avoidance of these activities are not understood. This study developed and tested a new measure assessing the tendency to avoid PA and sport because of weight stigma and appearance-related concerns. University students (n = 581, mean age = 19.8 years) completed an online survey at two time points. Demographic details and measures of weight stigmatization, appearance evaluations, and enjoyment and participation in PA or sport were taken. In addition, we developed and tested a new measure of the tendency to avoid physical activity and sport (TAPAS). Psychometric testing of the scale was conducted, and correlates of TAPAS were examined. The ten-item TAPAS provided a single factor solution, and the final scale score was predictive of lower levels of enjoyment of, and participation in, physical activity and sport (p < 0.001). The scale also displayed good internal and test-retest reliability. This study provides a new measure for assessing people’s tendency to avoid PA and sport because of weight stigma or appearance-related concerns. The results suggest that initiatives seeking to increase participation in PA and sport may need to address weight stigma and associated appearance related concerns.
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- 2022
157. Towards gas narcosis monitoring in compressed gas diving (PhD Academy Award)
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Vrijdag, Xavier C, primary
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- 2022
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158. Weight Stigma and Avoidance of Physical Activity and Sport: Development of a Scale and Establishment of Correlates
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Bevan, Nadia, primary, O’Brien, Kerry S., additional, Latner, Janet D., additional, Lin, Chung-Ying, additional, Vandenberg, Brian, additional, Jeanes, Ruth, additional, and Fung, Xavier C. C., additional
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- 2022
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159. A 35-bp Conserved Region Is Crucial for Insl3 Promoter Activity in Mouse MA-10 Leydig Cells
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Giner, Xavier C., primary, Pierre, Kenley Joule, additional, Robert, Nicholas M., additional, and Tremblay, Jacques J., additional
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- 2022
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160. Treatment Outcomes after Undetectable MRD with First-Line Ibrutinib (Ibr) Plus Venetoclax (Ven): Fixed Duration Treatment (Placebo) Versus Continued Ibr with up to 5 Years Median Follow-up in the CAPTIVATE Study
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Allan, John N., primary, Siddiqi, Tanya, additional, Kipps, Thomas J., additional, Kuss, Bryone J., additional, Badoux, Xavier C., additional, Barrientos, Jacqueline C., additional, Tedeschi, Alessandra, additional, Opat, Stephen, additional, Flinn, Ian W., additional, Gonzalez Barca, Eva, additional, Jacobs, Ryan, additional, Szafer-Glusman, Edith, additional, Zhou, Cathy, additional, Szoke, Anita, additional, Wierda, William G., additional, Ghia, Paolo, additional, and Tam, Constantine S., additional
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- 2022
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161. Recovery from open osteocapsular débridement for primary elbow osteoarthritis is rapid and does not depend on preoperative motion
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Ahmad, Farhan, primary, Ayala, Sal, additional, Mehta, Nabil, additional, Cohen, Mark S., additional, Simcock, Xavier C., additional, and Wysocki, Robert W., additional
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- 2022
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162. Design and implementation of a J2EE platform to handle standardized telematics emergency calls originated from vehicles.
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Josep L. Luque, Xavier C. Ferrer, and Xavier H. Serra
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- 2004
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163. Multifunctional coreid bug pheromones for efficient bioprotection against legume pests and enhanced food productivity
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Hilaire Kpongbe, Fathiya M. Khamis, Xavier Cheseto, Hillary K. Kirwa, Manuele Tamò, and Baldwyn Torto
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Clavigralla spp. ,Maruca vitrata ,Whiteflies ,Thrips ,Aggregation pheromone ,Natural enemy ,Agriculture - Abstract
Abstract Background In Africa, food legumes such as cowpeas and beans constitute important sources of proteins for millions of rural and urban populations. However, attacks by multiple pest species can reduce yields by up to 80%. Small-holder farmers protect their crops against pests using conventional insecticides, thereby contributing to insecticide resistance and jeopardizing food safety. To date, no alternative sustainable practices are available to reduce insecticide use in the management of legume pests. This study aimed to provide a sustainable alternative to insecticide use based on semiochemicals to manage multiple legume pest species and enhance food productivity. Results Using coupled gas chromatography-mass spectrometry (GC–MS) and coupled GC-electroantennographic detection (EAD) analyses, we identified 2-methylbutyl 2-methylbutanoate as the male-produced aggregation pheromone of the legume pest, Clavigralla elongata, a coreid bug species specific to East Africa. In multi-site field trials conducted in West Africa and East Africa, 2-methylbutyl 2-methylbutanoate and its analogue, isopentyl butanoate, previously identified from the pan-tropical coreid bug, C. tomentosicollis, both lured multiple legume insect pest species including from the Clavigralla genus, the legume pod-borer Maruca vitrata, flower thrips Megalurothrips sjostedti, and whitefly Bemisia tabaci into traps. Additionally, both pheromones lured the Clavigralla natural enemy parasitoid Gryon fulviventris into traps. The whitefly was only captured in pheromone-baited traps in East Africa. Deployment of an optimized pheromone trapping system significantly reduced legume pests and increased natural enemy density by up to sixfold compared to farmer practice (insecticide-treatment) and control. Legume yields for pheromone and insecticide treatments were comparable, ~ 320–590% higher than untreated controls. Conclusion These findings establish coreid bug pheromones as effective novel multifunctional semiochemical-based tools for sustainable legume pest management and production without insecticide use. Graphical abstract
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- 2024
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164. A novel trapped field magnet enabled by a quasi-operational HTS coil
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Hengpei Liao, Aleksandr Shchukin, Roshan Parajuli, Xavier Chaud, Jung-Bin Song, Min Zhang, and Weijia Yuan
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hts coils ,field cooling magnetization ,trapped field magnets ,hts coated conductors ,hts tape joints ,Production of electric energy or power. Powerplants. Central stations ,TK1001-1841 ,Renewable energy sources ,TJ807-830 - Abstract
This study introduces a novel approach to realizing compact high-field superconducting magnets by enabling a closed-loop high temperature superconducting (HTS) coil through magnetization. A circular closed-loop HTS coil is fabricated with a low resistive joint for field cooling magnetization. The HTS coil achieved a trapped field with only a 0.0087% decay in central field over 30 minutes. More interestingly, the central trapped field of 4.59 T exceeds the initial applied field of 4.5 T, while a peak trapped field of 6 T near the inner edge of the HTS coil, is identified through further numerical investigation. This phenomenon differs from the trapped field distributions observed in HTS bulks and stacks, where the trapped cannot exceed the applied one. Unique distributions of current density and magnetic field are identified as the reason for the trapped field exceeding the applied field. This study offers a new way to develop compact HTS magnets for a range of high-field applications such as superconducting magnetic energy storage (SMES) systems, superconducting machines, Maglev and proposes a viable method for amplifying the field strength beyond that of existing magnetic field source devices.
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- 2024
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165. In Silico Modeling and Characterization of Epstein–Barr Virus Latent Membrane Protein 1 Protein
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Dayang-Sharyati D. A. Salam, Kavinda Kashi Juliyan Gunasinghe, Siaw San Hwang, Irine Runnie Henry Ginjom, Xavier Chee Wezen, and Taufiq Rahman
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Chemistry ,QD1-999 - Published
- 2024
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166. The IL-1β inhibitor canakinumab in previously treated lower-risk myelodysplastic syndromes: a phase 2 clinical trial
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Juan Jose Rodriguez-Sevilla, Vera Adema, Kelly S. Chien, Sanam Loghavi, Feiyang Ma, Hui Yang, Guillermo Montalban-Bravo, Xuelin Huang, Xavier Calvo, Joby Joseph, Kristy Bodden, Guillermo Garcia-Manero, and Simona Colla
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Science - Abstract
Abstract In myelodysplastic syndromes (MDS), the IL-1β pathway is upregulated, and previous studies using mouse models of founder MDS mutations demonstrated that it enhances hematopoietic stem and progenitor cells’ (HSPCs’) aberrant differentiation towards the myeloid lineage at the expense of erythropoiesis. To evaluate whether targeting the IL-1β signaling pathway can rescue ineffective erythropoiesis in patients with MDS, we designed a phase 2 non-randomized single-arm clinical trial (NCT04239157) to assess the safety profile and efficacy of the IL-1β inhibitor canakinumab in previously treated lower-risk MDS patients. We enrolled 25 patients with a median age of 74 years; 60% were male, 16% had lower-risk MDS, 84% had intermediate-1 risk MDS according to the International Prognostic Scoring System score, and 80% failed hypomethylating agent therapy. The study met the primary endpoint of defining the clinical activity of canakinumab, and the secondary objective of determining the safety profile, including the rate of transfusion independence, the duration of response, progression-free survival, leukemia-free survival, and overall survival. The overall response rate was 17.4%, with all responses including hematological improvement. Sequential post-hoc prospective single-cell RNA sequencing analyses of HSPCs and bone marrow mononuclear cells at different time points during therapy showed that canakinumab’s on-target effects in hematopoietic populations expressing the IL-1β receptor decreased the TNF-mediated inflammatory signaling pathway but rescued ineffective erythropoiesis only in the context of lower genetic complexity. This study demonstrates that better stratification strategies could target lower-risk MDS patients more effectively.
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- 2024
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167. Heart failure hospitalization following surgical or transcatheter aortic valve implantation in low‐risk aortic stenosis
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Helena Lopez‐Martinez, Victoria Vilalta, Julio Farjat‐Pasos, Elena Ferrer‐Sistach, Siamak Mohammadi, Claudia Escabia, Dimitri Kalavrouziotis, Helena Resta, Andrea Borrellas, Eric Dumont, Xavier Carrillo, Jean‐Michel Paradis, Eduard Fernández‐Nofrerías, Victoria Delgado, Josep Rodés‐Cabau, and Antoni Bayes‐Genis
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Aortic stenosis cardiomyopathy ,Aortic valve stenosis ,Heart failure ,Mortality ,Prostheses and implants ,Diseases of the circulatory (Cardiovascular) system ,RC666-701 - Abstract
Abstract Aims In low‐risk patients with severe aortic stenosis (AS), sutureless surgical aortic valve replacement (SU‐SAVR) may be an alternative to transcatheter aortic valve implantation (TAVI). The risk of heart failure hospitalization (HFH) after aortic valve replacement (AVR) in this population is incompletely characterized. This study aims to investigate the incidence, predictors, and outcomes of HFH in patients undergoing SU‐SAVR versus TAVI. Methods and results Patients referred for AVR between 2013 and 2020 at two centres were consecutively included. The decision for SU‐SAVR or TAVI was determined by a multidisciplinary Heart Team. Cox regression and competing risk analysis were conducted to assess adverse events. Of 594 patients (mean age 77.5 ± 6.4, 59.8% male), 424 underwent SU‐SAVR, while 170 underwent TAVI. Following a mean follow‐up of 34.1 ± 23.1 months, HFH occurred in 112 (27.8%) SU‐SAVR patients and in 8 (4.8%) TAVI patients (P
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- 2024
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168. Key role for inflammation-related signaling in the pathogenesis of myopia based on evidence from proteomics analysis
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Liqin Jiang, James H. Z. Koh, Sherlyn H. Y. Seah, Yee Shan Dan, Zhaoran Wang, Xavier Chan, Lei Zhou, Veluchamy Amutha Barathi, and Quan V. Hoang
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Myopia ,Proteomics ,Signaling pathways ,Inflammation ,Innate immunity ,Medicine ,Science - Abstract
Abstract The mechanisms underlying myopia pathogenesis are not well understood. Using publicly-available human and animal datasets, we expound on the roles of known, implicated proteins, and new myopia-related signaling pathways were hypothesized. Proteins identified from human serum or ocular fluids, and from ocular tissues in myopic animal models, were uploaded and analyzed with the QIAGEN Ingenuity Pathway Analysis (IPA) software (March 2023). With each IPA database update, more potentially-relevant proteins and signaling pathways previously unavailable during data acquisition are added, allowing extraction of novel conclusions from existing data. Canonical pathway analysis was used to analyze these data and calculate an IPA activation z-score—which indicates not only whether an association is significant, but also whether the pathway is likely activated or inhibited. Cellular immune response and cytokine signaling were frequently found to be affected in both human and animal myopia studies. Analysis of two publicly-available proteomic datasets highlighted a potential role of the innate immune system and inflammation in myopia development, detailing specific signaling pathways involved such as Granzyme A (GzmA) and S100 family signaling in the retina, and activation of myofibroblast trans-differentiation in the sclera. This perspective in myopia research may facilitate development of more effective and targeted therapeutic agents.
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- 2024
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169. Tractography of sensorimotor pathways in dyskinetic cerebral palsy: Association with motor function
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Xavier Caldú, Lee B. Reid, Kerstin Pannek, Jurgen Fripp, Júlia Ballester‐Plané, David Leiva, Roslyn N. Boyd, Roser Pueyo, and Olga Laporta‐Hoyos
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Neurosciences. Biological psychiatry. Neuropsychiatry ,RC321-571 ,Neurology. Diseases of the nervous system ,RC346-429 - Abstract
Abstract Objectives Neuroimaging studies of dyskinetic cerebral palsy (CP) are scarce and the neuropathological underpinnings are not fully understood. We delineated the corticospinal tract (CST) and cortico‐striatal‐thalamocortical (CSTC) pathways with probabilistic tractography to assess their (1) integrity and (2) association with motor functioning in people with dyskinetic CP. Methods Diffusion weighted magnetic resonance images were obtained for 33 individuals with dyskinetic CP and 33 controls. Fractional anisotropy (FA) and mean diffusivity (MD) for the CST and the CSTC pathways were compared between groups. Correlation analyses were performed between tensor metric values and motor function scores of participants with dyskinetic CP as assessed by the Gross Motor Function Classification System (GMFCS), the Bimanual Fine Motor Function (BFMF), and the Manual Ability Classification System (MACS). Results White matter integrity in both the CST and the CSTC pathways was reduced in people with dyskinetic CP. The GMFCS, MACS and, less commonly, the BFMF were associated with FA and, particularly, MD in most portions of these pathways. Interpretation The present study advances our understanding of the involvement of white matter microstructure in sensorimotor pathways and its relationship with motor impairment in people with dyskinetic CP. Our results are consistent with well‐described relationships between upper limb function and white matter integrity in the CST and CSTC pathways in other forms of CP. This knowledge may ultimately help prognosis and therapeutic programmes.
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- 2024
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170. Diversity of fish otoliths from the Gulf of Mexico and the Caribbean Sea: Report on the first digital collection of fish otoliths (Actinopterygii) from the Atlantic region of Mexico
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Maribel Badillo Alemán, Ariana Solís Gómez, Alfredo Gallardo Torres, Eduardo Pacheco Gongora, and Xavier Chiappa-Carrara
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Aquaculture. Fisheries. Angling ,SH1-691 - Abstract
The Otolith Collection of Fishes from the Gulf of Mexico and Caribbean Sea was created with the objective to conserve and illustrate the diversity of these structures from species living in the Gulf of Mexico, the Caribbean Sea, and the freshwater and brackish systems of the Yucatan Peninsula, incorporating morphological descriptions and morphometric data. Otoliths, non-skeletal calcareous structures that develop in the inner ear of fish, are essential for balance and hearing. They have become pivotal tools for age and growth determination, population analysis, and ecological, trophic, and archaeological studies due to their resistance to degradation and the extensive information they provide about the environment and physiology of fish. The collection now includes otoliths from 214 species, representing 67 families, obtained through sampling campaigns and collaborations with local fishermen. The otoliths are extracted using techniques that ensure the integrity of the structures for later preservation. High-resolution images were obtained using optical and scanning electron microscopy, and these images are stored in an online database. This database facilitates research and teaching by providing public access to digital specimens and associated data. In addition to fostering academic development, this collection represents a significant step towards the creation of a national platform for otolith data analysis, aligned with international efforts to digitize biological collections. Despite the financial and logistical challenges involved in building and maintaining biological collections, this collection demonstrates its value as an essential resource for taxonomic, systematic, and ecological studies, as well as for biodiversity education and awareness. The online availability of the collection not only facilitates access to data but also promotes innovation and international collaboration in the study of fishes and their habitats.
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- 2024
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171. Arterial blood gas measurements during deep open-water breath-hold dives
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David Mullins, Peter Mesley, Xavier C. E. Vrijdag, Tom Scott, Simon J Mitchell, and Hanna van Waart
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Male ,Physiology ,Diving ,Partial Pressure ,sports ,chemistry.chemical_element ,Oxygen ,Free diving ,Breath Holding ,chemistry.chemical_compound ,Maximum depth ,Physiology (medical) ,medicine ,Humans ,Water ,Apnea ,Open water ,chemistry ,Carbon dioxide ,Breathing ,sports.sport ,Environmental science ,Arterial blood ,Blood Gas Analysis ,medicine.symptom ,human activities ,Research Article ,Biomedical engineering - Abstract
Arterial blood gas (ABG) measurements at both maximum depth and at resurfacing prior to breathing have not previously been measured during free dives conducted to extreme depth in cold open-water conditions. An elite free diver was instrumented with a left radial arterial cannula connected to two sampling syringes through a low-volume splitting device. He performed two open-water dives to a depth of 60 m (197′, 7 atmospheres absolute pressure) in the constant weight with fins competition format. ABG samples were drawn at 60 m (by a mixed-gas scuba diver) and again on resurfacing before breathing. An immersed surface static apnea, of identical length to the dives and with ABG sampling at identical times, was also performed. Both dives lasted approximately 2 min. Arterial partial pressure of oxygen ([Formula: see text]) increased during descent from an indicative baseline of 15.8 kPa (after hyperventilation and glossopharyngeal insufflation) to 42.8 and 33.3 kPa (dives 1 and 2) and decreased precipitously (to 8.2 and 8.6 kPa) during ascent. Arterial partial pressure of carbon dioxide ([Formula: see text]) also increased from a low indicative baseline of 2.8 kPa to 6.3 and 5.1 kPa on dives 1 and 2; an increase not explained by metabolic production of CO(2) alone since [Formula: see text] actually decreased during ascent (to 5.2 and 4.5 kPa). Surface static apnea caused a steady decrease in [Formula: see text] and increase in [Formula: see text] without the inflections provoked by depth changes. Lung compression and expansion provoke significant changes in both [Formula: see text] and [Formula: see text] during rapid descent and ascent on a deep free dive. These changes generally support predictive hypotheses and previous findings in less extreme settings. NEW & NOTEWORTHY Arterial blood gas measurements at both maximum depth and the surface before breathing on the same dive have not previously been obtained during deep breath-hold dives in cold open-water conditions and competition dive format. Such measurements were obtained in two dives to 60 m (197′) of 2 min duration. Changes in arterial oxygen and carbon dioxide (an increase during descent, and a decrease during ascent) support previous observations in less extreme dives and environments.
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- 2021
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172. Progression of Glenoid Morphology in Glenohumeral Osteoarthritis
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Walker, Kyle E., Simcock, Xavier C., Jun, Bong Jae, Iannotti, Joseph P., and Ricchetti, Eric T.
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- 2018
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173. Vertebrate faunal diversity in Mt. Calavite Wildlife Sanctuary, Occidental Mindoro, Philippines: An assessment using the Biodiversity Assessment and Monitoring System (BAMS)
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Phillip A. Alviola, Nelson M. Pampolina, Ericson E. Coracero, Jestine Crhistia V. Gatdula, Dexter Cabahug, Robert Duquil, Manuel Luis N. Vida, Paul Xavier C. Medallon, Jomari Christian D.C. Baggay, and Mark John A. Suniega
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birds ,mammals ,Biodiversity ,herpetofauna ,Mindoro Endemics ,threatened fauna ,Philippine endemics ,reptiles - Abstract
Rich biodiversity is one of the Philippines' greatest assets of which populations of flora and fauna continuously face massive threats due to anthropogenic interventions. This study in Mt. Calavite Wildlife Sanctuary (MCWS) is one of the pioneering research projects on vertebrate fauna in a permanent biodiversity monitoring plot that followed a nationally accepted system of biodiversity assessment and monitoring for species and habitat conservation. The study established a 2-ha Permanent Biodiversity Monitoring Area (PBMA) following the procedures in the Biodiversity Assessment and Monitoring System crafted by the Department of Environment and Natural Resources – Biodiversity Management Bureau. Results showed that MCWS was home to different kinds of vertebrate fauna including 23 bird species from 17 families, 7 mammalian species from 6 families, and 8 herpetofauna species from 7 families. The habitat association assessment revealed that the majority of species were forest-dependent and some were associated with grassland, agricultural areas, and forest streams. The computed diversity values in MCWS were generally higher than in other areas in the Philippines. Lastly, a high percentage of ecologically important species were recorded including the native, endemic, and threatened species. The study revealed the presence of essential species that shall be prioritized for conservation. The product of this study can act as baseline information for the continuous monitoring of the area and can further be used in crafting more appropriate and comprehensive conservation and management plans for the area.
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- 2022
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174. A systematic review of electroencephalography in acute cerebral hypoxia: clinical and diving implications.
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Wong, Nicole Y. E., van Waart, Hanna, Sleigh, Jamie W., Mitchell, Simon J., and Vrijdag, Xavier C. E.
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Introduction: Hypoxia can cause central nervous system dysfunction and injury. Hypoxia is a particular risk during rebreather diving. Given its subtle symptom profile and its catastrophic consequences there is a need for reliable hypoxia monitoring. Electroencephalography (EEG) is being investigated as a real time monitor for multiple diving problems related to inspired gas, including hypoxia. Methods: A systematic literature search identified articles investigating the relationship between EEG changes and acute cerebral hypoxia in healthy adults. Quality of clinical evidence was assessed using the Newcastle-Ottawa scale. Results: Eighty-one studies were included for analysis. Only one study investigated divers. Twelve studies described quantitative EEG spectral power differences. Moderate hypoxia tended to result in increased alpha activity. With severe hypoxia, alpha activity decreased whilst delta and theta activities increased. However, since studies that utilised cognitive testing during the hypoxic exposure more frequently reported opposite results it appears cognitive processing might mask hypoxic EEG changes. Other analysis techniques (evoked potentials and electrical equivalents of dipole signals), demonstrated sustained regulation of autonomic responses despite worsening hypoxia. Other studies utilised quantitative EEG analysis techniques, (Bispectral index [BISTM], approximate entropy and Lempel-Ziv complexity). No change was reported in BISTM value, whilst an increase in approximate entropy and Lempel-Ziv complexity occurred with worsening hypoxia. Conclusions: Electroencephalographic frequency patterns change in response to acute cerebral hypoxia. There is paucity of literature on the relationship between quantitative EEG analysis techniques and cerebral hypoxia. Because of the conflicting results in EEG power frequency analysis, future research needs to quantitatively define a hypoxia-EEG response curve, and how it is altered by concurrent cognitive task loading. [ABSTRACT FROM AUTHOR]
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- 2023
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175. Unpacking the benefits of black soldier fly frass fertilizer towards nematode suppression and potato production
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Emmanuel O. Anedo, Dennis Beesigamukama, Benson Mochoge, Nicholas K. Korir, Solveig Haukeland, Xavier Cheseto, Moses Nyongesa, Patrick Pwaipwai, Sevgan Subramanian, Abdou Tenkouano, Betty Kibaara, and Chrysantus M. Tanga
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insect-derived chitin ,potato yield ,nematodes ,regenerative agriculture ,circular economy ,Plant culture ,SB1-1110 - Abstract
Potato production is hindered by soil degradation and nematode infestation. Mineral fertilizers and synthetic nematicides are costly and cause negative impacts on humans and the environment, while organic fertilizers are less effective for soil health and nematode management. This study demonstrates the contribution of black soldier fly frass fertilizer (BSFFF) in nematode suppression and potato productivity when compared to commercial mineral fertilizer, organic fertilizer (SAFI), and nematicide. The on-farm experiments consisted of eight treatments: BSFFF, SAFI, BSFFF+5%chitin, NPK+nematicide, 50%BSFFF+50%NPK, 50%SAFI+50%NPK, 50%BSFFF+5% chitin+50%NPK, and control (unfertilized soil). Results revealed that all fertilizer treatments significantly increased potato growth, number of tubers (34 – 61%), and tuber yield (20 – 72%) relative to the control. Application of BSFFF+5% chitin produced 9 – 28% higher tubers per plant compared to other treatments. Over 26% higher tuber yield was achieved using BSFFF+5% chitin compared to NPK+nematicide treatment. Soil amendment with BSFFF+5% chitin caused 5–35% higher reduction in the number of cysts per 200 g soil-1 compared to NPK+nematicide and SAFI treatments. The same treatment reduced the PCN reproduction rate by 20% and 75% compared to NPK + nematicide and SAFI, respectively. Both BSFFF and NPK+nematicide treatments achieved comparable suppression of the number of eggs and infective juveniles (J2) per cyst-1 and eggs g-1 of soil. However, BSFFF+5% chitin reduced the number of eggs and J2 per cyst-1 and eggs g-1 of soil by 55–92% compared to SAFI. Our findings demonstrate that chitin-fortified BSFFF can significantly contribute to potato cyst nematode suppression and boost potato yields in smallholder farming systems, thus, making it a promising and sustainable alternative to commercial fertilizers and nematicides. Adopting this regenerative and multipurpose fertilizer will reduce reliance on synthetic fertilizers and nematicides, which are costly and harmful to the environment and human health.
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- 2025
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176. Community Use and Perceptions of Climate Shelters in Schoolyards in Barcelona
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Marta Sanz-Mas, Xavier Continente, Marc Marí-Dell’Olmo, and María José López
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climate change adaptation ,community ,schools ,thermal comfort ,urban health ,Public aspects of medicine ,RA1-1270 - Abstract
ObjectivesThis study explores the use and perceptions of thermal comfort and wellbeing among the local community in the schoolyards in Barcelona that had been transformed into accessible climate shelters.MethodsWe conducted a qualitative evaluation through a spontaneous ethnographic approach, combining 22 non-participant observations in the 11 transformed schoolyards with brief spontaneous interviews with 76 users and 18 caretakers who supervised the schoolyards during non-school days (June–July 2022). We conducted a thematic content analysis. We analyzed user characteristics, thermal comfort and wellbeing, activities and differences by age and gender, social behavior, additional benefits, and areas for improvement.ResultsAdapted schoolyards were mostly visited by families and groups of adolescents with a higher proportion of boys. Participants reported that shade provided coolness and comfort, vegetation offered pleasant and naturalized environments, and water features were enjoyed for their cooling capacity and play opportunities. Schoolyards were mainly used as places for outdoor recreation and socialization.ConclusionThis study provides policymakers with evidence to support the transformation of schoolyards into climate shelters, creating comfortable outdoor recreational areas for the surrounding urban community.
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- 2025
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177. γδ T Cells’ Role in Donor-Specific Antibody Generation: Insights From Transplant Recipients and Experimental Models
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Xavier Charmetant, Guillaume Rigault, Chien-Chia Chen, Hannah Kaminski, Jonathan Visentin, Benjamin Taton, Gabriel Marseres, Virginie Mathias, Alice Koenig, Thomas Barba, Pierre Merville, Stéphanie Graff-Dubois, Emmanuel Morelon, Julie Déchanet-Merville, Valérie Dubois, Jean-Paul Duong van Huyen, Lionel Couzi, and Olivier Thaunat
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humoral response ,translational science ,gamma delta T cell ,donor specific antibody (DSA) ,B cell ,Specialties of internal medicine ,RC581-951 - Abstract
The generation of donor-specific antibodies (DSA) requires that alloreactive B cells receive help from follicular helper T (TFH) cells. Recent works have suggested that γδ T cells could contribute to T cell-dependent humoral responses, leading us to investigate their role in DSA generation. Analysis of a cohort of 331 kidney transplant recipients found no relation between the number of circulating γδ T cells and the risk to develop DSA. Coculture models demonstrated that activated γδ T cells were unable to promote the differentiation of B cells into plasma cells, ruling out that they can be “surrogate” TFH. In line with this, γδ T cells preferentially localized outside the B cell follicles, in the T cell area of lymph nodes, suggesting that they could instead act as “antigen-presenting cell” (APC) to prime αβ TFH. This hypothesis was proven wrong since γδ T cells failed to acquire APC functions in vitro. These findings were validated in vivo by the demonstration that following transplantation with an allogeneic Balb/c (H2d) heart, wild-type and TCRδKO C57BL/6 (H2b) mice developed similar DSA responses, whereas TCRαKO recipients did not develop DSA. We concluded that the generation of DSA is unfazed by the absence of γδ T cells.
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- 2025
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178. Emotional words evoke region- and valence-specific patterns of concurrent neuromodulator release in human thalamus and cortex
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Seth R. Batten, Alec E. Hartle, Leonardo S. Barbosa, Beniamino Hadj-Amar, Dan Bang, Natalie Melville, Tom Twomey, Jason P. White, Alexis Torres, Xavier Celaya, Samuel M. McClure, Gene A. Brewer, Terry Lohrenz, Kenneth T. Kishida, Robert W. Bina, Mark R. Witcher, Marina Vannucci, Brooks Casas, Pearl Chiu, Pendleton R. Montague, and William M. Howe
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CP: Neuroscience ,Biology (General) ,QH301-705.5 - Abstract
Summary: Words represent a uniquely human information channel—humans use words to express thoughts and feelings and to assign emotional valence to experience. Work from model organisms suggests that valence assignments are carried out in part by the neuromodulators dopamine, serotonin, and norepinephrine. Here, we ask whether valence signaling by these neuromodulators extends to word semantics in humans by measuring sub-second neuromodulator dynamics in the thalamus (N = 13) and anterior cingulate cortex (N = 6) of individuals evaluating positive, negative, and neutrally valenced words. Our combined results suggest that valenced words modulate neuromodulator release in both the thalamus and cortex, but with region- and valence-specific response patterns, as well as hemispheric dependence for dopamine release in the anterior cingulate. Overall, these experiments provide evidence that neuromodulator-dependent valence signaling extends to word semantics in humans, but not in a simple one-valence-per-transmitter fashion.
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- 2025
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179. Quantum gravitational corrections in cosmology
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Xavier Calmet, Roberto Casadio, and Marco Sebastianutti
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Physics ,QC1-999 - Abstract
We show how to reliably calculate quantum gravitational corrections to cosmological models using the unique effective action formalism for quantum gravity. Our calculations are model independent and apply to any ultra-violet complete theory of quantum gravity that admit general relativity as a low energy theory. We show that it is important to consider the full effective action to obtain renormalization group invariant solutions. We investigate the validity range of our techniques within simple cosmological models.
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- 2025
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180. Relationship Between Preoperative and Postoperative Motion After Four-Corner Wrist Fusion for Osteoarthritis: Clustering and Regression Analyses
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Ahmad, Farhan, primary, Ayala, Salvador, additional, Smith, Shelby, additional, Fernandez, John J., additional, Cohen, Mark S., additional, Simcock, Xavier C., additional, and Wysocki, Robert W., additional
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- 2022
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181. Coping Strategies Adopted by Motor Vehicle Accident Survivors from a Hilly State of North India
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Arora, Deeksha, primary, Belsiyal, Xavier C., additional, and Rawat, Vikram Singh, additional
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- 2022
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182. O12 Comparison of jejunum and ileum electrogenic transport and epithelium integrity in growing cattle from three different cross-breeds
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Tretola, M., primary, Silacci, P., additional, Morel, I., additional, Dohme-Meier, F., additional, Xavier, C., additional, and Lerch, S., additional
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- 2022
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183. O185 In vivo 3D imaging to estimate the dynamic of body chemical composition along the growth of crossbred bulls
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Xavier, C., primary, Morel, I., additional, Le Cozler, Y., additional, Siegenthaler, R., additional, Dohme-Meier, F., additional, and Lerch, S., additional
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- 2022
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184. EPH114 Leading Predictors and Their Associations with Combination Pain Therapy in Older Adults with Cancer: Application of Machine Learning Approaches
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Xavier, C, primary, Manning, S, additional, Madhavan, S, additional, Rasu, R, additional, and Sambamoorthi, U, additional
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- 2022
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185. Does hyperbaric oxygen cause narcosis or hyperexcitability? A quantitative EEG analysis
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Vrijdag, Xavier C. E., primary, van Waart, Hanna, additional, Sames, Chris, additional, Mitchell, Simon J., additional, and Sleigh, Jamie W., additional
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- 2022
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186. Policy analysis: User monitoring of in-vitro diagnostic medical devices used for near-patient testing of infectious diseases
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Dimech, Wayne, primary, Lamoury, Francois, additional, Ding, Xavier C, additional, Lastra, Leticia Megias, additional, Vincini, Giuseppe, additional, and Sands, Anita, additional
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- 2022
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187. A NEW CONCEPTUAL FRAMEWORK OF SALES FORCE CONTROL SYSTEMS
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Darmon, René Y. and Martin, Xavier C.
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- 2011
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188. Diagnosis of Plasmodium vivax by Loop-Mediated Isothermal Amplification in Febrile Patient Samples from Loreto, Perú
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Berónica Infante, Dionicia Gamboa, Oscar Nolasco, Xavier C. Ding, Sandra Incardona, Katherine Torres, and Juan Contreras-Mancilla
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medicine.medical_specialty ,Loreto ,030231 tropical medicine ,Plasmodium vivax ,Loop-mediated isothermal amplification ,Gastroenterology ,Isothermal Amplification ,Perú ,03 medical and health sciences ,0302 clinical medicine ,Febrile Patient Samples ,Virology ,Internal medicine ,parasitic diseases ,medicine ,biology ,business.industry ,Plasmodium falciparum ,medicine.disease ,biology.organism_classification ,Infectious Diseases ,Parasitology ,business ,purl.org/pe-repo/ocde/ford#3.03.06 [https] ,Malaria ,Kappa - Abstract
Plasmodium vivax is co-endemic with Plasmodium falciparum in Peru, and optimum management requires distinguishing these two species in the blood of patients. For the differential identification of P. vivax and other Plasmodium spp., the LoopampTM Malaria Pan Detection Kit in combination with the Loopamp Malaria Pv Detection Kit (Eiken Chemical Co. Ltd., Tokyo, Japan) was used to evaluate 559 whole blood samples collected in 2017 from febrile patients with suspected malaria attending different health facilities in the Loreto region. The Loopamp Malaria Pan Detection Kit showed a sensitivity of 87.7% (95% CI: 83.5-91.9) and a specificity of 94.4% (95% CI: 91.9-96.9) and good agreement with PCR (Cohen's kappa 0.8266, 95% CI: 0.7792-0.874). By comparison, the Loopamp Malaria Pv Detection Kit showed a similar sensitivity (84.4%, 95% CI: 79.0-89.7) and specificity (92.4%, 95% CI: 89.7-95.0) and substantial agreement with PCR (Cohen's kappa: 0.7661, 95% CI: 0.7088-0.8234).
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- 2020
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189. Evaluation of highly sensitive diagnostic tools for the detection of P. falciparum in pregnant women attending antenatal care visits in Colombia
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Iveth J. González, Xavier C. Ding, Ana Campillo, Sean C. Murphy, Ana María Vásquez, Elisa Serra-Casas, A. Medina, A. Tobón Castaño, Annette M. Seilie, and Gabriel Velez
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Adult ,medicine.medical_specialty ,Malaria in pregnancy ,Plasmodium falciparum ,030231 tropical medicine ,Reproductive medicine ,Context (language use) ,Rapid diagnostic test ,Colombia ,Real-Time Polymerase Chain Reaction ,Diagnostic tools ,Sensitivity and Specificity ,lcsh:Gynecology and obstetrics ,Young Adult ,03 medical and health sciences ,0302 clinical medicine ,Pregnancy ,parasitic diseases ,Humans ,Medicine ,Loop mediated isothermal DNA amplification (LAMP) ,030212 general & internal medicine ,Malaria, Falciparum ,Diagnostics ,Parasite density ,lcsh:RG1-991 ,Microscopy ,business.industry ,Obstetrics ,Obstetrics and Gynecology ,Prenatal Care ,Nucleic acid amplification technique ,Highly sensitive ,Nucleic acid amplification techniques ,Cross-Sectional Studies ,Molecular Diagnostic Techniques ,Pregnancy Complications, Parasitic ,Female ,business ,Research Article - Abstract
Background In low transmission settings early diagnosis is the main strategy to reduce adverse outcomes of malaria in pregnancy; however, microscopy and rapid diagnostic tests (RDTs) are inadequate for detecting low-density infections. We studied the performance of the highly sensitive-RDT (hsRDT) and the loop mediated isothermal DNA amplification (LAMP) for the detection of P. falciparum in pregnant women. Methods A cross-sectional study was conducted in two malaria-endemic municipalities in Colombia. We screened pregnant women in the context of an antenatal care program in health facilities and evaluated five tests (microscopy, conventional RDT, hsRDT, LAMP and nested polymerase chain reaction-PCR) for the detection of P. falciparum in peripheral blood, using a quantitative reverse transcription PCR (qRT-PCR) as the reference standard. Diagnostic performance of hsRDT and LAMP were compared with routine testing. Results The prevalence of P. falciparum was 4.5% by qRT-PCR, half of those infections were subpatent. The sensitivity of the hsRDT (64.1%) was slightly better compared to microscopy and cRDT (59 and 53.8% respectively). LAMP had the highest sensitivity (89.7%) for detecting P. falciparum and the ability to detect very low-density infections (minimum parasite density detected 0.08 p/μL). Conclusions There is an underestimation of Plasmodium spp. infections by tests routinely used in pregnant women attending antenatal care visits. LAMP methodology can be successfully implemented at local hospitals in malaria-endemic areas. The relevance of detecting and treating this sub-patent P. falciparum infections in pregnant women should be evaluated. Trial registration ClinicalTrials.gov, Identifier: NCT03172221, Date of registration: May 29, 2017.
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- 2020
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190. A Genotyping Study in Benin Comparing the Carriage of Plasmodium falciparum Infections Before Pregnancy and in Early Pregnancy: Story of a Persistent Infection
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JAFARI-GUEMOURI, Sayeh, COURTOIS, Laura, MAMA, Atika, ROUAS, Baptiste, NETO BRAGA, Gabriel, ACCROMBESSI, Manfred, MASSOUGBODJI, Achille, DING, Xavier C., TUIKUE NDAM, Nicaise, FIEVET, Nadine, BRIAND, Valerie, Mère et enfant en milieu tropical : pathogènes, système de santé et transition épidémiologique (MERIT - UMR_D 261), Institut de Recherche pour le Développement (IRD)-Université Paris Cité (UPCité), London School of Hygiene and Tropical Medicine (LSHTM), Bordeaux population health (BPH), Université de Bordeaux (UB)-Institut de Santé Publique, d'Épidémiologie et de Développement (ISPED)-Institut National de la Santé et de la Recherche Médicale (INSERM), Bill and Melinda Gates Foundation, Agence Nationale de la Recherche, ANR-13-JSV1-0004,RECIPAL,Impact du paludisme précoce au cours de la grossesse sur la croissance fœtale au Bénin(2013), Mère et enfant en milieu tropical : pathogènes, système de santé et transition épidémiologique (MERIT - UMR_D 216), and Institut de Recherche pour le Développement (IRD)-Université de Paris (UP)
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Genotype ,polymerase chain reaction ,Plasmodium falciparum ,malaria ,[SDV.MHEP.GEO]Life Sciences [q-bio]/Human health and pathology/Gynecology and obstetrics ,Major Articles and Commentaries ,AcademicSubjects/MED00290 ,[SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases ,Pregnancy ,parasitic diseases ,Africa ,genotyping techniques ,Benin ,Humans ,[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie ,Female ,Malaria, Falciparum ,Online Only Articles ,Child - Abstract
Background Malaria infections in the first trimester of pregnancy are frequent and deleterious for both mother and child health. To investigate if these early infections are newly acquired or already present in the host, we assessed whether parasites detected before pregnancy and those detected in early pregnancy are the same infection. Methods We used data from the preconceptional “RECIPAL” study (Benin, 2014–2017). Sixty-three pregnant women of 411 included who had a malaria infection detected by quantitative polymerase chain reaction both before pregnancy and at the first antenatal care (ANC) visit were selected for this study. Two highly polymorphic markers, msp-2 and glurp, and a fragment-analysis method were used to enumerate the Plasmodium falciparum genotypes and to quantify their proportions within isolates. An infection was considered as persistent when identical msp-2 and glurp genotypes were found in the corresponding prepregnancy and early-pregnancy samples. Results The median time between the 2 malaria screenings was 3 months. The median gestational age at the first ANC visit was 6.4 weeks. Most infections before pregnancy were submicroscopic infections. Based on both msp-2 and glurp genotyping, the infection was similar before and in early pregnancy in 46% (29/63) of cases. Conclusions Almost half of P. falciparum infections detected in the first trimester originate before pregnancy. Protecting young women from malaria infection before pregnancy might reduce the prevalence of malaria in early pregnancy and its related poor maternal and birth outcomes., To distinguish between new and persistent malaria infection in early pregnancy, we enumerated and compared Plasmodium falciparum genotypes in isolates both before and in the first weeks of pregnancy. Persistent infections from preconception accounted for half the cases.
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- 2020
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191. High resolution, non-contact surface metrology for freeform optics in digital immersive displays
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Alexander Sohn, Nelson Cardenas, Neil Naples, Xavier C. Colonna de Lega, Jan C. Liesener, Thomas Dresel, and Peter de Groot
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- 2022
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192. CLL-057 Outcomes in High-Risk Subgroups After Fixed-Duration Ibrutinib (Ibr) + Venetoclax (Ven) for Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL): Up to 5.5 Years of Follow-Up in the Phase 2 CAPTIVATE Study
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Wierda, William G., Jacobs, Ryan, Barr, Paul M., Allan, John N., Siddiqi, Tanya, Tedeschi, Alessandra, Kipps, Thomas J., O'Brien, Susan M., Badoux, Xavier C., Visentin, Andrea, Lasica, Masa, Carney, Dennis, Elinder Camburn, Anna, De la Serna, Javier, Szafer-Glusman, Edith, Zhou, Cathy, Szoke, Anita, Dean, James P., Ghia, Paolo, and Tam, Constantine S.
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- 2024
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193. Outcomes in High-Risk Subgroups After Fixed-Duration Ibrutinib (Ibr) + Venetoclax (Ven) for Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL): Up to 5.5 Years of Follow-Up in the Phase 2 CAPTIVATE Study
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Wierda, William G., Jacobs, Ryan, Barr, Paul M., Allan, John N., Siddiqi, Tanya, Tedeschi, Alessandra, Kipps, Thomas J., O'Brien, Susan M., Badoux, Xavier C., Visentin, Andrea, Lasica, Masa, Carney, Dennis, Elinder Camburn, Anna, De la Serna, Javier, Szafer-Glusman, Edith, Zhou, Cathy, Szoke, Anita, Dean, James P., Ghia, Paolo, and Tam, Constantine S.
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- 2024
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194. Secrets, Unveilings and Frauds: A General Framework and the Study of a Special Case.
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Xavier C. Delannoy and C. Del Vigna
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- 1998
195. Static Classification Schemes for an Object System.
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Ana Simonet, Michel Simonet, Cyr Gabin Bassolet, Xavier C. Delannoy, and Riad Hamadi
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- 1998
196. Database Views with Dynamic Assertions.
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Xavier C. Delannoy, Ana Simonet, and Michel Simonet
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- 1996
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197. Understanding the Tension between Transition Rules and Confidentiality.
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Xavier C. Delannoy
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- 1996
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198. Lenalidomide as initial therapy of elderly patients with chronic lymphocytic leukemia
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Badoux, Xavier C., Keating, Michael J., Wen, Sijin, Lee, Bang-Ning, Sivina, Mariela, Reuben, James, Wierda, William G., O'Brien, Susan M., Faderl, Stefan, Kornblau, Steven M., Burger, Jan A., and Ferrajoli, Alessandra
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- 2011
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199. Cyclophosphamide, fludarabine, alemtuzumab, and rituximab as salvage therapy for heavily pretreated patients with chronic lymphocytic leukemia
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Badoux, Xavier C., Keating, Michael J., Wang, Xuemei, O'Brien, Susan M., Ferrajoli, Alessandra, Faderl, Stefan, Burger, Jan, Koller, Charles, Lerner, Susan, Kantarjian, Hagop, and Wierda, William G.
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- 2011
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200. Fludarabine, cyclophosphamide, and rituximab chemoimmunotherapy is highly effective treatment for relapsed patients with CLL
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Badoux, Xavier C., Keating, Michael J., Wang, Xuemei, O'Brien, Susan M., Ferrajoli, Alessandra, Faderl, Stefan, Burger, Jan, Koller, Charles, Lerner, Susan, Kantarjian, Hagop, and Wierda, William G.
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- 2011
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