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978 results on '"Yanai K"'

152. MEASUREMENT OF ELEMENTAL DISTRIBUTIONS IN MOUSE BRAIN BY USING SUBMILLI-PIXE CAMERA

Author

FUJIKI, K., primary, MATSUYAMA, S., additional, ISHII, K., additional, YAMAZAKI, H., additional, TERAKAWA, A., additional, KIKUSHI, Y., additional, FUJIWARA, M., additional, KAWAMURA, Y., additional, OKURA, S., additional, FUJIKAWA, M., additional, CATELLA, G., additional, HASHIMOTO, Y., additional, HATORI, Y., additional, HAMADA, N., additional, SAKURAI, E., additional, and YANAI, K., additional

Published
2010
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157. Over 5,600 Japanese collection of Antarctic meteorites: Recoveries, curation and distribution

Author

Yanai, K and Kojima, H

Subjects
Astrophysics
Abstract

The history of recovery of meteorite fragments in the Yamato Mountains, Allan Hills, and Victoria Land, Antarctica is reviewed. The Japanese collection of Antarctic meteorites were numbered, weighed, photographed, identified, and classified. Sample distribution of the Japanese Antarctic meteorites is described.

Published
1986

159. Organic analysis of the Antarctic carbonaceous chondrites

Author

Kotra, R. K, Shimoyama, A, Ponnamperuma, C, Hare, P. E, and Yanai, K

Subjects
Space Biology
Abstract

Thus far, organic analysis of carbonaceous chondrites has proven the only fruitful means of examining complex organic matter of extraterrestrial origin. The present paper presents the results of organic analysis of two Antarctic meteorites, Allan Hills (77306) and Yamato (74662), which may be considered free from terrestrial contamination. Ion-exchange chromatography, gas chromatography and mass spectrometery of meteorite samples reveal the presence in Yamato of 15 and in Allan Hills of 20 protein and nonprotein amino acids, the most abundant of which are glycine and alanine. Abundances of the D and L enantiomers of each amino acid are also found to be nearly equal. Data thus indicate an abiotic extraterrestrial origin for the matter, and confirm a lack of terrestrial contamination.

Published
1981

160. Amino acids in the Yamato carbonaceous chrondrite from Antarctica

Author

Shimoyama, A, Ponnamperuma, C, and Yanai, K

Subjects
Space Biology
Abstract

Evidence for the presence of amino acids of extraterrestrial origin in the Antarctic Yamato carbonaceous chrondrite is presented. Hydrolyzed and nonhydrolyzed water-extracted amino acid samples from exterior, middle and interior portions of the meteorite were analyzed by an amino acid analyzer and by gas chromatography of N-TFA-isopropyl amino acid derivatives. Nine protein and six nonprotein amino acids were detected in the meteorite at abundances between 34 and less than one nmole/g, with equal amounts in interior and exterior portions. Nearly equal abundances of the D and L enantiomers of alanine, aspartic acid and glutamic acid were found, indicating the abiotic, therefore extraterrestrial, origin of the amino acids. The Antarctic environment and the uniformity of protein amino acid abundances are discussed as evidence against the racemization of terrestrially acquired amino acids, and similarities between Yamato amino acid compositions and the amino acid compositions of the Murchison and Murray type II carbonaceous chrondrites are indicated.

Published
1979

161. Total carbon and sulfur abundances in Antarctic meteorites

Author

Gibson, E. K., Jr and Yanai, K

Subjects
Lunar And Planetary Exploration
Abstract

Total carbon and sulfur abundances have been measured in five Antarctic meteorites. Two C2 carbonaceous chondrites Yamato 74662 and Allan Hills 77306 have sulfur abundances (3.490 plus or minus .040% and 3.863 plus or minus 0.050% respectively) similar to other C2 chondrites but their carbon abundances (1.514 plus or minus 0.050% and 1.324 plus or minus .040% respectively) are lower than previously measured C2 chondrites. The decreased carbon abundances may reflect the effects of weathering in cold environments. Carbon and sulfur abundances for one C4 carbonaceous chondrite, one E4 enstatite chondrite and one ureilite are similar to values reported previously for meteorites of the same petrologic grades.

Published
1979

162. The Yamato-74659 ureilite and some new findings on the Yamato achondritic pyroxenes

Author

Takeda, H, Miyamoto, M, Duke, M. B, and Yanai, K

Subjects
Lunar And Planetary Exploration
Abstract

A cube-like fragment with an approximately 4 mm edge was taken from the Yamato-74659 meteorite for the mineralogical and crystallographic examination discussed in the present paper. An analysis of powdered fragments by a standard wet chemical method showed that it matched to weathered ureilite. The chemical composition was found to differ from other ureilites in that the FeO content (8.83 wt%) is the lowest among known ureilites and it is richer in SiO2 contents (42.91 wt%).

Published
1978

165. High-density association study and nomination of susceptibility genes for hypertension in the Japanese National Project

Author

Kato, N., primary, Miyata, T., additional, Tabara, Y., additional, Katsuya, T., additional, Yanai, K., additional, Hanada, H., additional, Kamide, K., additional, Nakura, J., additional, Kohara, K., additional, Takeuchi, F., additional, Mano, H., additional, Yasunami, M., additional, Kimura, A., additional, Kita, Y., additional, Ueshima, H., additional, Nakayama, T., additional, Soma, M., additional, Hata, A., additional, Fujioka, A., additional, Kawano, Y., additional, Nakao, K., additional, Sekine, A., additional, Yoshida, T., additional, Nakamura, Y., additional, Saruta, T., additional, Ogihara, T., additional, Sugano, S., additional, Miki, T., additional, and Tomoike, H., additional

Published
2007
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166. Search of type 2 diabetes susceptibility gene on chromosome 20q

Author

Takeuchi, F., primary, Yanai, K., additional, Inomata, H., additional, Kuzuya, N., additional, Kajio, H., additional, Honjo, S., additional, Takeda, N., additional, Kaburagi, Y., additional, Yasuda, K., additional, Shirasawa, S., additional, Sasazuki, T., additional, and Kato, N., additional

Published
2007
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168. Strategies of RC Delay Reduction in 45 nm BEOL Technology

Author

Kudo, H., primary, Ochimizu, H., additional, Tsukune, A., additional, Okano, S., additional, Naitou, K., additional, Sakamoto, M., additional, Takesako, S., additional, Shirasu, T., additional, Asneil, A., additional, Idani, N., additional, Sugimoto, K., additional, Ozaki, S., additional, Nakata, Y., additional, Owada, T., additional, Watatani, H., additional, Ohara, N., additional, Ohtsuka, N., additional, Sunayama, M., additional, Sakai, H., additional, Oryoji, M., additional, Akiyama, S., additional, Iwata, H., additional, Yamamoto, H., additional, Shimoda, Y., additional, Yao, T., additional, Suda, S., additional, Suzuki, T., additional, Sakai, S., additional, Kitada, H., additional, Amari, S., additional, Tabira, T., additional, Matsuura, A., additional, Iba, Y., additional, Mizushima, Y., additional, Matsuyama, H., additional, Suzuki, Y., additional, Shimizu, N., additional, Yanai, K., additional, Nakaishi, M., additional, Futatsugi, T., additional, Hanyu, I., additional, Nakamura, T., additional, and Sugii, T., additional

Published
2007
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169. Néel-type skyrmion lattice with confined orientation in the polar magnetic semiconductor GaV4S8.

Author

Kézsmárki, I., Bordács, S., Milde, P., Neuber, E., Eng, L. M., White, J. S., Rønnow, H. M., Dewhurst, C. D., Mochizuki, M., Yanai, K., Nakamura, H., Ehlers, D., Tsurkan, V., and Loidl, A.

Subjects
SKYRMIONS, MAGNETIC semiconductors, MAGNETIC crystals, MAGNETIC fields, CYCLOIDS
Abstract

Following the early prediction of the skyrmion lattice (SkL)-a periodic array of spin vortices-it has been observed recently in various magnetic crystals mostly with chiral structure. Although non-chiral but polar crystals with Cnv symmetry were identified as ideal SkL hosts in pioneering theoretical studies, this archetype of SkL has remained experimentally unexplored. Here, we report the discovery of a SkL in the polar magnetic semiconductor GaV4S8 with rhombohedral (C3v) symmetry and easy axis anisotropy. The SkL exists over an unusually broad temperature range compared with other bulk crystals and the orientation of the vortices is not controlled by the external magnetic field, but instead confined to the magnetic easy axis. Supporting theory attributes these unique features to a new Néel-type of SkL describable as a superposition of spin cycloids in contrast to the Bloch-type SkL in chiral magnets described in terms of spin helices. [ABSTRACT FROM AUTHOR]

Published
2015
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171. DEVELOPMENT OF AN IN-AIR ON/OFF AXIS STIM SYSTEM FOR QUANTITATIVE ELEMENTAL MAPPING

Author

INOMATA, K., primary, ISHII, K., additional, YAMAZAKI, H., additional, MATSUYAMA, S., additional, KIKUCHI, Y., additional, WATANABE, Y., additional, ISHIZAKI, A., additional, OYAMA, R., additional, KAWAMURA, Y., additional, YAMAGUCHI, T., additional, MOMOSE, G., additional, SAKURAI, E., additional, YANAI, K., additional, KAMIYA, T., additional, SAKAI, T., additional, SATOH, T., additional, OIKAWA, M., additional, and ARAKAWA, K., additional

Published
2006
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173. GENETIC ANALYSIS OF METABOLIC SYNDROME IN RATS

Author

Wssatanabe, T., primary, Liang, Y.-Q., additional, Inomata, H., additional, Yanai, K., additional, Yazaki, Y., additional, Sasazuki, T., additional, Kato, N., additional, lizuka, Y., additional, Gotoda, T., additional, and Isobe, M., additional

Published
2004
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190. Measurement of hypocretin/orexin content in the mouse brain using an enzyme immunoassay: the effect of circadian time, age and genetic background

Author

Lin, L., primary, Wisor, J., additional, Shiba, T., additional, Taheri, S., additional, Yanai, K., additional, Wurts, S., additional, Lin, X., additional, Vitaterna, M., additional, Takahashi, J., additional, Lovenberg, T.W., additional, Koehl, M., additional, Uhl, G., additional, Nishino, S., additional, and Mignot, E., additional

Published
2002
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196. Renin-dependent cardiovascular functions and renin-independent blood-brain barrier functions revealed by renin-deficient mice.

Author

Yanai, K, Saito, T, Kakinuma, Y, Kon, Y, Hirota, K, Taniguchi-Yanai, K, Nishijo, N, Shigematsu, Y, Horiguchi, H, Kasuya, Y, Sugiyama, F, Yagami, K i, Murakami, K, and Fukamizu, A

Abstract

Renin plays a key role in controlling blood pressure through its specific cleavage of angiotensinogen to generate angiotensin I (AI). Although possible existence of the other angiotensin forming enzymes has been discussed to date, its in vivo function remains to be elucidated. To address the contribution of renin, we generated renin knockout mice. Homozygous mutant mice show neither detectable levels of plasma renin activity nor plasma AI, lowered blood pressure 20-30 mm Hg less than normal, increased urine and drinking volume, and altered renal morphology as those observed in angiotensinogen-deficient mice. We recently found the decreased density in granular layer cells of hippocampus and the impaired blood-brain barrier function in angiotensinogen-deficient mice. Surprisingly, however, such brain phenotypes were not observed in renin-deficient mice. Our results demonstrate an indispensable role for renin in the circulating angiotensin generation and in the maintenance of blood pressure, but suggest a dispensable role for renin in the blood-brain barrier function.

Published
2000

197. The expression and function of histamine H3 receptors in pancreatic beta cells.

Author

Nakamura, T, Yoshikawa, T, Noguchi, N, Sugawara, A, Kasajima, A, Sasano, H, and Yanai, K

Subjects
PANCREATIC beta cells, HISTAMINE receptors, GENE expression, HOMEOSTASIS, CENTRAL nervous system, WESTERN immunoblotting, CELLULAR signal transduction, INSULIN, PHARMACOLOGY
Abstract

Background and Purpose Histamine and its receptors in the CNS play important roles in energy homeostasis. Here, we have investigated the expression and role of histamine receptors in pancreatic beta cells, which secrete insulin. Experimental Approach The expression of histamine receptors in pancreatic beta cells was examined by RT- PCR, Western blotting and immunostaining. Insulin secretion assay, ATP measurement and calcium imaging studies were performed to determine the function and signalling pathway of histamine H3 receptors in glucose-induced insulin secretion ( GIIS) from MIN6 cells, a mouse pancreatic beta cell line. The function and signalling pathway of H3 receptors in MIN6 cell proliferation were examined using pharmacological assay and Western blotting. Key Results Histamine H3 receptors were expressed in pancreatic beta cells. A selective H3 receptor agonist, imetit, and a selective inverse H3 receptor agonist, JNJ-5207852, had inhibitory and facilitatory effects, respectively, on GIIS in MIN6 cells. Neither imetit nor JNJ-5207852 altered intracellular ATP concentration, or intracellular calcium concentration stimulated by glucose and KCl, indicating that GIIS signalling was affected by H3 receptor signalling downstream of the increase in intracellular calcium concentration. Moreover, imetit attenuated bromodeoxyuridine incorporation in MIN6 cells. The phosphorylation of cAMP response element-binding protein ( CREB), which facilitated beta cell proliferation, was inhibited, though not significantly, by imetit, indicating that activated H3 receptors inhibited MIN6 cell proliferation, possibly by decreasing CREB phosphorylation. Conclusions and Implications Histamine H3 receptors were expressed in mouse beta cells and could play a role in insulin secretion and, possibly, beta cell proliferation. [ABSTRACT FROM AUTHOR]

Published
2014
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