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965 results on '"Yang, Lulu"'

151. Associations of Insomnia With Insulin Resistance Traits: A Cross-sectional and Mendelian Randomization Study

Author

Wang, Xiaoyu, primary, Zhao, Chenhao, additional, Feng, Hongliang, additional, Li, Guohua, additional, He, Lei, additional, Yang, Lulu, additional, Liang, Yan, additional, Tan, Xiao, additional, Xu, Yanmin, additional, Cui, Ruixiang, additional, Sun, Yujing, additional, Guo, Sheng, additional, Zhao, Guoan, additional, Zhang, Jihui, additional, and Ai, Sizhi, additional

Published
2023
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153. Pulmonary rehabilitation restores limb muscle mitochondria and improves the intramuscular metabolic profile

Author

Qumu, Shiwei, primary, Sun, Weiliang, additional, Guo, Jing, additional, Zhang, Yuting, additional, Cai, Lesi, additional, Si, Chaozeng, additional, Xu, Xia, additional, Yang, Lulu, additional, Situ, Xuanming, additional, Yang, Tianyi, additional, He, Jiaze, additional, Shi, Minghui, additional, Liu, Dongyan, additional, Ren, Xiaoxia, additional, Huang, Ke, additional, Niu, Hongtao, additional, Li, Hong, additional, Yu, Chang’An, additional, Chen, Yang, additional, and Yang, Ting, additional

Published
2023
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154. Association between accelerometer-measured amplitude of rest-activity rhythm and future health risk : a prospective cohort study of the UK Biobank

Author

Feng, Hongliang, Yang, Lulu, Ai, Sizhi, Liu, Yue, Zhang, Weijie, Lei, Binbin, Chen, Jie, Liu, Yaping, Chan, Joey W Y, Chan, Ngan Yin, Tan, Xiao, Wang, Ningjian, Benedict, Christian, Jia, Fujun, Wing, Yun Kwok, Zhang, Jihui, Feng, Hongliang, Yang, Lulu, Ai, Sizhi, Liu, Yue, Zhang, Weijie, Lei, Binbin, Chen, Jie, Liu, Yaping, Chan, Joey W Y, Chan, Ngan Yin, Tan, Xiao, Wang, Ningjian, Benedict, Christian, Jia, Fujun, Wing, Yun Kwok, and Zhang, Jihui

Abstract

BACKGROUND: The health effects of rest-activity rhythm are of major interest to public health, but its associations with health outcomes remain elusive. We aimed to examine the associations between accelerometer-measured rest-activity rhythm amplitude and health risks among the general UK population. METHODS: We did a prospective cohort analysis of UK Biobank participants aged 43-79 years with valid wrist-worn accelerometer data. Low rest-activity rhythm amplitude was defined as the first quintile of relative amplitude; all other quintiles were classified as high rest-activity rhythm amplitude. Outcomes of interest were defined using International Classification of Diseases 10th Revision codes and consisted of incident cancer and cardiovascular, infectious, respiratory, and digestive diseases, and all-cause and disease-specific (cardiovascular, cancer, and respiratory) mortality. Participants with a current diagnosis of any outcome of interest were excluded. We assessed the associations between decreased rest-activity rhythm amplitude and outcomes using Cox proportional hazards models. FINDINGS: Between June 1, 2013, and Dec 23, 2015, 103 682 participants with available raw accelerometer data were enrolled. 92 614 participants (52 219 [56·4%] women and 40 395 [42·6%] men) with a median age of 64 years (IQR 56-69) were recruited. Median follow-up was 6·4 years (IQR 5·8-6·9). Decreased rest-activity rhythm amplitude was significantly associated with increased incidence of cardiovascular diseases (adjusted hazard ratio 1·11 [95% CI 1·05-1·16]), cancer (1·08 [1·01-1·16]), infectious diseases (1·31 [1·22-1·41]), respiratory diseases (1·26 [1·19-1·34]), and digestive diseases (1·08 [1·03-1·14]), as well as all-cause mortality (1·54 [1·40-1·70]) and disease-specific mortality (1·73 [1·34-2·22] for cardiovascular diseases, 1·32 [1·13-1·55] for cancer, and 1·62 [1·25-2·09] for respiratory diseases). Most of these associations were not modified by age older than 65 years or s

Published
2023
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156. Measurement of Land Ecological Security in the Middle and Lower Reaches of the Yangtze River Base on the PSR Model.

Author

Yu, Song, Yang, Lulu, Song, Zhenjiang, Li, Wenbo, Ye, Yongmei, and Liu, Bin

Abstract

To accurately identify the land ecological security in the middle and lower reaches of the Yangtze River, we measured the land ecological security based on the PSR model, selected a total of 19 indicators, such as population density, and applied the methods of system evaluation value conversion, comprehensive evaluation value and coordination degree measurement to study the land ecological security in the region. Research findings: The comprehensive evaluation level showed that Jiangxi, Shanghai, and Hunan had comprehensive evaluation values according to the regional forefront. The subsystem evaluation level showed that Shanghai and Hunan had higher pressure subsystem evaluation values relative to other provinces; Shanghai, Zhejiang, and Anhui had higher state subsystem evaluation values relative to other provinces; and Jiangxi was much more responsive to land ecological security issues than were other provinces and cities in the region. The system coordination degree showed that the comprehensive evaluation value of land ecological safety and the coordination degree evaluation value of other provinces except Shanghai and Hunan showed a negative correlation, indicating certain land ecological safety problems in the region. Finally, suggested reflections based on the conclusions are presented. [ABSTRACT FROM AUTHOR]

Published
2023
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161. Low-dose X-ray radiodynamic therapy solely based on gold nanoclusters for efficient treatment of deep hypoxic solid tumors combined with enhanced antitumor immune response

Author

Zhu, Shengcang, primary, Yan, Feihong, additional, Yang, Lulu, additional, Li, Bingyi, additional, Xue, Ruxian, additional, Yu, Wenwen, additional, Wang, Yu, additional, Huang, Lu, additional, Wang, Lijun, additional, Han, Rongcheng, additional, and Jiang, Yuqiang, additional

Published
2023
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179. Associations of Childhood Maltreatment and Genetic Risks With Incident Heart Failure in Later Life

Author

Liang, Yannis Yan, primary, Ai, Sizhi, additional, Weng, Foqian, additional, Feng, Hongliang, additional, Yang, Lulu, additional, He, Zhixuan, additional, Xue, Huachen, additional, Zhou, Mingqing, additional, Shu, Xinyue, additional, Chen, Yilin, additional, Ma, Huan, additional, Guo, Lan, additional, Geng, Qingshan, additional, and Zhang, Jihui, additional

Published
2022
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181. Efficacy and safety of margetuximab plus chemotherapy vs. trastuzumab plus chemotherapy in Chinese patients with pretreated HER2-positive advanced metastatic breast cancer: results from a randomized, open-label, multicenter, phase II bridging study

Author

Zhang, Qingyuan, primary, Ouyang, Quchang, additional, Li, Wei, additional, Chiu, Joanne, additional, Yan, Min, additional, Lu, Yen-Shen, additional, Sun, Sanyuan, additional, Li, Huiping, additional, Du, Yingying, additional, Wang, Xujuan, additional, Sun, Tao, additional, Yin, Yongmei, additional, Wang, Haibo, additional, Ye, Feng, additional, Shen, Kunwei, additional, Wang, Jingfen, additional, Pan, Yueyin, additional, Wang, Shusen, additional, Yang, Jin, additional, Wu, Xiaohong, additional, Dai, Ming-Shen, additional, Cheng, Jing, additional, Teng, Yuee, additional, Su, Fang, additional, Wu, Xinhong, additional, He, Jingdong, additional, Fu, Peifen, additional, Yang, Lulu, additional, Xin, Yuan, additional, Wang, Xiaojia, additional, and Jiang, Zefei, additional

Published
2022
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186. Neutralization of Omicron BA.4/BA.5 and BA.2.75 by Booster Vaccination or BA.2 Breakthrough Infection Sera

Author

Wang, Xun, primary, Ai, Jingwen, additional, Li, Xiangnan, additional, Zhao, Xiaoyu, additional, Wu, Jing, additional, Zhang, Haocheng, additional, He, Xing, additional, Zhao, Chaoyue, additional, Qiao, Rui, additional, Li, Minghui, additional, Cui, Yuchen, additional, Chen, Yanjia, additional, Yang, Lulu, additional, Hu, Zixin, additional, Xu, Chenqi, additional, Zhang, Wenhong, additional, and Wang, Pengfei, additional

Published
2022
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187. Antibody evasion of SARS-CoV-2 Omicron BA.1, BA.1.1, BA.2, and BA.3 sub-lineages

Author

Ai, Jingwen, primary, Wang, Xun, additional, He, Xinyi, additional, Zhao, Xiaoyu, additional, Zhang, Yi, additional, Jiang, Yuchao, additional, Li, Minghui, additional, Cui, Yuchen, additional, Chen, Yanjia, additional, Qiao, Rui, additional, Li, Lin, additional, Yang, Lulu, additional, Li, Yi, additional, Hu, Zixin, additional, Zhang, Wenhong, additional, and Wang, Pengfei, additional

Published
2022
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190. Oxygen-Loaded Lipid Nanobubbles for Biofilm Eradication by Combined Trimodal Treatment of Oxygen, Silver, and Photodynamic Therapy.

Author

Ye, Lingyu, Yang, Lulu, Tan, Xinyi, Yang, Pingwei, Liu, Ying, Peng, Juanjuan, Zhao, Lingzhi, and Zhou, Yunyun

Abstract

The hypoxic microenvironment of bacterial biofilms is one of the main causes of their recalcitrance. The combined therapy of photodynamic therapy (PDT) and silver nanoparticles (AgNPs) has shown its potential for biofilm eradication. However, hypoxia can not only restrict the efficiency of the oxygen-dependent PDT but also encumber the oxidizing release of the Ag+ cations from the AgNPs, thus greatly impeding the therapeutic performance of the combined treatment. Here, a liposomal delivery system is developed using cationic phospholipid for the synergistic ablation of both Gram-positive and Gram-negative bacteria and their biofilms, which is formed using cationic phospholipid and loaded with oxygen, Ce6, and silver nanoparticles. The positively charged micelles increased the adhesion and penetration to the negatively charged biofilm, and the loaded perfluorohexane (PFH) acted as an oxygen carrier to overcome the hypoxia microenvironment and promoted the performance of PDT. The reactive oxygen species generated in the PDT then stimulated the oxidative dissolution of the Ag+. In vivo antibacterial therapy on mice with subcutaneous abscess demonstrated its strong sterilizing capability on living tissues. This research developed a trimodal treatment for effective biofilm eradication, providing a way for the management of biofilm-associated infections. [ABSTRACT FROM AUTHOR]

Published
2023
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192. Artificial neural network - based estimation of root zone soil moisture in the western Liaohe river basin.

Author

GUO Xiaomeng, FANG Xiuqin, YANG Lulu, and CAO Yu

Subjects
SOIL moisture, WATERSHEDS, WATER conservation, CROP yields, SOIL conservation, WIND speed
Abstract

Soil moisture is the core of water conversion and circulation that connects the atmosphere, surface, soil, and subsurface. As a basic climate variable of the global climate observing system, soil moisture plays a vital role in regional -scale water and energy exchange. The estimation of root zone soil moisture (RZSM) and the analysis of its spatio - temporal variations are of great significance for crop yield assessment, flood and drought prediction, and soil and water conservation. Based on the artificial neural network (ANN), this study estimated the daily RZSM in the Western Liaohe River basin during 2019-2020 with remote sensing image - based surface soil moisture, cumulative precipitation, cumulative daily maximum and minimum temperatures, relative humidity, sunshine duration, cloud coverage, wind speed, soil attributes, normalized difference vegetation index, and actual evapotranspiration as explanatory variables, the in - situ measured RZSM as the target variable, and the 2013-2018 data used for model training. The estimated results show that the average RMSE and average R between the RZSM estimated based on ANN and the in - situ measured RZSM were 0.056 7 m³/m³ and 0.611 7, respectively. Therefore, the ANN can effectively estimate the RZSM in the Western Liaohe River basin. In addition, this study shows that the variation in the soil moisture is closely related to precipitation. [ABSTRACT FROM AUTHOR]

Published
2023
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193. On structure and substructure fault tolerance of star networks.

Author

Yang, Lulu, Hua, Xiaohui, and Yang, Yuxing

Subjects
*FAULT tolerance (Engineering), *SUBGRAPHS, *MULTIPROCESSORS, *FAULT-tolerant computing
Abstract

Let H and M be two connected subgraphs of an interconnection network G. If the removal of any minimum H-structure-cut (resp. H-substructure-cut) isolates a component isomorphic to M, then G is said to be super H | M -connected (resp. super sub- H | M -connected). Furthermore, if the removal of any minimum H-structure-cut (resp. minimum H-substructure-cut) splits G into exactly two components, one of which is isomorphic to M, then G is said to be hyper H | M -connected (resp. hyper sub- H | M -connected). The n-dimensional star network S n is one of alternative interconnection networks for multiprocessor systems. Let n ≥ 4 . In this paper, we prove that S n is hyper H | K 1 -connected and hyper sub- H | K 1 -connected for H ∈ { K 1 , r , P 5 } and 1 ≤ r ≤ n - 3 , S n is hyper P 4 | K 1 , 1 -connected and hyper sub- P 4 | K 1 , 1 -connected, S n with n ≥ 5 is super C 6 | K 1 -connected, and S n is hyper sub- C 6 | K 1 -connected, where K 1 is the complete graph on one vertex and K 1 , r is a star on 1 + r vertices, P k is a path on k vertices and C 6 is a cycle on 6 vertices. [ABSTRACT FROM AUTHOR]

Published
2023
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