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166. Proton Radiotherapy for Hodgkin's Lymphoma

Author

Rodriguez, C., primary, Chera, B.S., additional, Morris, C.G., additional, Yeung, D., additional, Olivier, K.R., additional, Louis, D., additional, Li, Z., additional, and Mendenhall, N.P., additional

Published
2008
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181. 2363

Author

Yeung, D., primary, Malyapa, R.S., additional, Mendenhall, W.M., additional, Li, Z., additional, Louis, D., additional, Liu, C., additional, Amdur, R.J., additional, Palta, J.R., additional, and Mendenhall, N.P., additional

Published
2006
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186. Determining the Effectiveness of a New Device for Hand Therapy (The FEPSim Device): Feasibility Protocol for a Randomized Controlled Trial Study

Author

Miguel-Cruz Sr, Antonio, Guptill, Christine, Gregson, Geoffrey, Ladurner, Anna-Maria, Holmes, Cindy, Yeung, Daniel, Siebert, Justine, Dziwenko, Gwen, and Ríos Rincón, Adriana

Subjects
Medicine, Computer applications to medicine. Medical informatics, R858-859.7
Abstract

BackgroundImpairments of the forearm, wrist, and hand affect a sizable proportion of individuals and impose a significant economic burden on health care systems. FEPSim is a medical device for hand and wrist rehabilitation. The FEPSim device could be part of the standard of care for upper extremity rehabilitation during therapeutic activities to increase range of motion, dexterity, and strength. FEPSim has not yet been tested in a health care setting; therefore, a trial of the effectiveness of FEPSim in upper extremity rehabilitation is warranted. ObjectiveThis study aims to assess the feasibility of conducting a definitive trial in terms of recruitment, eligibility criteria, the type and number of diagnoses included, the length and dosage of the intervention, and data collection methods. This study also aims to gather clinical and statistical information as well as information related to the cost and usability, which allows for an economic evaluation of the device. MethodsThe trial will use a randomized controlled design comprising 47 intervention participants and 47 control group participants. Participants will be adults (age≥18 years) attending outpatient rehabilitation with limitations in their forearm, wrist, or hand function due to distal radial or ulnar fractures, stroke, or osteoarthritis. This study’s primary outcome variables are related to patients’ range of motion and strength, specifically active and passive wrist flexion and extension range of motion; active and passive forearm pronation and supination range of motion; grip strength; and pinch strength. The secondary outcome variables are related to patients’ perceived wrist pain and disability in activities of daily living. The patients’ perceived wrist pain and disability in activities of daily living will be measured using the patient-rated wrist evaluation questionnaire. The control group will receive the standard of care at each of the 2 hospital facilities (Glenrose Rehabilitation and Royal Alexandra Hospitals). The intervention group will receive the same standard of care as the control group at each facility and will use the FEPSim device for therapeutic activities to increase strength, range of motion, resistance, and dexterity. All the participants will be assessed at baseline (week 0); weeks 2, 4, and 8; and postintervention (week 10). ResultsThe FEPSim study was launched in April 2020. This study is currently on hold because of the global COVID-19 pandemic. The recruitment process is expected to resume by September 2020, and the primary impact analysis is expected to be conducted by December 2020. ConclusionsThis study will provide valuable information on the measurement of comparative intervention effects, technology acceptance by hand therapists, and how associated treatment and product costs will contribute to the evidence planning process, which will be crucial for the future adoption of FEPSim. Trial RegistrationInternational Standard Randomized Controlled Trial Number Registry ISRCTN13656014; https://www.isrctn.com/ISRCTN13656014 International Registered Report Identifier (IRRID)PRR1-10.2196/22145

Published
2021
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190. ASAB: a Chinese screen reader

Author

Luk, R. W. P., primary, Yeung, D. S., additional, Lu, Q., additional, Leung, H. L., additional, Li, S. Y., additional, and Leung, F., additional

Published
2003
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200. Growth of breast-fed infants deviates from current reference data: A pooled analysis of US, Canadian, and European data sets

Author

Dewey, Kathryn G., Peerson, Janet M., Brown, Kathryn H., Krebs, N. F., Michaelsen, Kim F., Persson, L. A., Salmenpera, L., Whitehead, R. G., Yeung, D. L., Anderson, M. A., Dewey, K. G., Frongillo, E., Garza, C., Haschke, F., Kramer, M., Winichagoon, P., Dewey, Kathryn G., Peerson, Janet M., Brown, Kathryn H., Krebs, N. F., Michaelsen, Kim F., Persson, L. A., Salmenpera, L., Whitehead, R. G., Yeung, D. L., Anderson, M. A., Dewey, K. G., Frongillo, E., Garza, C., Haschke, F., Kramer, M., and Winichagoon, P.

Abstract

Objective: To compare growth patterns of a large sample of breast-fed infants with the current World Health Organization (WHO)/Centers for Disease Control and Prevention (CDC) reference data. Methods: Data from seven longitudinal studies of infant growth in North America and northern Europe were pooled (n = 453 breast-fed infants). Weight, length and head circumference were compared with the WHO/CDC reference, and repeated-measures analysis of variance was used to examine associations between growth patterns and breast-feeding duration, age of introduction of solid foods, and use of other milks. Results: In comparison with WHO/CDC reference data, infants breast-fed for at least 12 months (n = 226) grew more rapidly in the first 2 months and less rapidly (particularly in weight) from 3 to 12 months; the mean z score at 12 months was -0.53 for weight for age, -0.29 for length for age, and -0.32 for weight for length. In contrast, mean head circumference was well above the WHO/CDC median throughout the first year of life. These patterns were generally consistent across studies. In the full sample (n = 453), a longer duration of breast-feeding was associated with a greater decline in weight for age and weight for length but not length for age. Conclusion: These results suggest that if growth charts are to reflect patterns consistent with those of infants following WHO feeding recommendations, new reference data based on breast-fed infants are needed.

Published
1995

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