151. The impact of social factors, especially psychological worries on anxiety and depression in patients with epilepsy.
- Author
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Li, Ping, Lin, Jiahe, Wu, Chunmei, Huang, Shanshan, and Zhu, Suiqiang
- Subjects
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MENTAL depression , *PEOPLE with epilepsy , *COVID-19 , *SOCIAL factors , *LIFE satisfaction , *WORRY , *SOCIAL anxiety - Abstract
• The prevalence of anxiety and depression decreased during the lockdown period. • The prevalence rallied to the prior epidemiological level after reopening. • Poor seizure control was a risk factor for epileptic psychological comorbidities. • Demographics and low life satisfaction were associated with mental disorders. • Psychological worry was a risk factor for mental health in some patients with epilepsy. Social factors are believed to affect mental health in patients with epilepsy (PWE). However, there is still a lack of sufficient manifest proof, given the difficulty of exposing PWE to relatively consistent natural social environments with a low or high level of social interaction to study their significant role. This single-center, longitudinal study was conducted via online questionnaires during the coronavirus disease 2019. PWE were recruited from downtown Wuhan and surrounding areas. The Patient Health Questionnaire-9 and Generalized Anxiety Disorder-7 were used to assess psychological status. We analyzed 588 questionnaires completed by 294 PWE who participated in the dual survey. Under lockdown and reopening, the prevalence of anxiety was 13.6%/22.5%, and the prevalence of depression was 19.4%/34.0%. Raising children and seizure-related characteristics, including uncontrolled seizures, seizure exacerbation, seizure frequency ≥ 2/m, and changes in drug regimen, were risk factors in the first and second surveys. A high education level (OR = 1.946, 95% CI = 1.191–3.182), low life satisfaction (OR = 1.940, 95% CI = 1.007–3.737), worry about unanticipated seizures (OR = 2.147, 95% CI = 1.049–4.309), and worry about purchasing medication outside (OR = 2.063, 95% CI = 1.060–4.016) were risk factors for higher scores after reopening. Worry about unanticipated seizures (OR = 3.012, 95% CI = 1.302–6.965) and in-person medical consultation (OR = 2.319, 95% CI = 1.262–4.261) were related to newly diagnosed patients with psychological disorder after reopening. We identified an association between social variables and epileptic psychiatric comorbidities. [ABSTRACT FROM AUTHOR]
- Published
- 2021
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