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Childhood trauma is a risk factor for self-harm/suicidal behavior, but research on the potential association linking sleep quality and anxiety symptoms to childhood trauma and self-harm attempt is limited. The aim of this study was to describe the mediating role of sleep quality and anxiety symptoms between childhood trauma and self-harm attempt, and to provide a scientific basis for the prevention of self-harm behaviors. This study ultimately included 11,063 study participants who participated in the baseline survey of this large prospective cohort study of the UK Biobank. We used structural equation modeling (SEM) to analyze the chain mediating role of sleep quality and anxiety symptoms in childhood trauma and self-harm attempt while controlling for covariates. A total of 19.58 % of study participants self-reported self-harm attempt. Sleep quality was negatively correlated with childhood trauma, anxiety symptoms, and self-harm attempt (p < 0.01). Childhood trauma, anxiety symptoms, and self-harm attempt were positively correlated (p < 0.01). In addition, after adjusting for confounders, anxiety symptoms were able to partially mediate the association between childhood trauma and self-harm attempt (effect value: 0.042, p < 0.01), and sleep quality and anxiety symptoms can chain mediate the association between childhood trauma and self-harm attempt (effect value:0.002, p < 0.01), with a total mediating effect of 65.67 % of the total effect. Subgroup analyses further showed that the mediating effects of sleep quality and anxiety symptoms on childhood trauma and self-harm attempt differed across age, gender, ethnicity, and smoking and drinking subgroups. This study found a complex relationship between childhood trauma, sleep quality, anxiety symptoms, and self-harm attempt, with sleep quality and anxiety symptoms mediating the relationship between childhood trauma and self-harm attempt. Multiple avenues of intervention, such as the provision of professional psychological interventions and timely monitoring, should be used to improve the sleep quality and mental health of individuals with traumatic childhood experiences and to prevent the occurrence of emotionally harmful behaviors such as self-harm/suicide. • Childhood trauma can negatively influence anxiety symptoms and self-harm attempt, and positively influence sleep quality. Anxiety symptoms can positively influence self-harm attempt. Sleep quality can negatively influence self-harm attempt and anxiety symptoms. • Anxiety symptoms were able to partially mediate the association between childhood trauma and self-harm attempt. And sleep quality and anxiety symptoms can chain mediate the association between childhood trauma and self-harm attempt. • Subgroup analyses showed that the mediating effects of sleep quality and anxiety symptoms on childhood trauma and self-harm attempt differed across characteristics. [ABSTRACT FROM AUTHOR]

Both adverse childhood experiences (ACEs) and lifestyle factors have been associated with risk of cardiovascular diseases (CVDs) in later life, but whether and to what extent adherence to a healthy lifestyle in adulthood can offset the increased cardiovascular risk associated with ACEs is unclear. We aimed to determine whether and to what extent adopting to a healthy lifestyle in adulthood can offset the risk of CVDs in individuals according to their ACEs. A prospective cohort study included 143,869 participants aged 38–72 years, free of CVDs at baseline from the UK Biobank. The history of ACEs was assessed using the Childhood Trauma Screener. Participants were divided into three risk groups based on ACEs: low (no ACEs), intermediate (one or two ACEs), and high (three or more ACEs). A healthy lifestyle score in adulthood was constructed as the sum of four modifiable lifestyle factors (no smoking, adequate physical activity, healthy diet, no obesity), and participants were then categorized into three groups based on this score (unfavorable [0–1 point], intermediate [2–3 points], favorable [4 points]). Cox proportional hazard models were conducted to investigate the association between ACEs, healthy lifestyle, and incident CVDs. During a median follow-up of 12.49 years, 13,373 incident cases of overall CVDs were identified. This included 7521 cases of coronary heart disease (CHD), 6175 cases of atrial fibrillation (AF) and 1813 cases of stroke. Individuals with high ACEs had a greater risk of incident overall CVDs (hazard ratio [HR] = 1.39, [95%CI = 1.29 to 1.50]), CHD (1.50 [1.36 to 1.65]) and AF (1.18 [1.05 to 1.33]) compared to those with low ACEs. The risk of CVDs decreased moving from unfavorable to favorable lifestyle categories (P for trend<0.001), with the lowest risk observed among individuals with a favorable lifestyle (0.70 [0.66 to 0.74] for overall CVDs, 0.69 [0.64 to 0.75] for CHD, and 0.71 [0.65 to 0.78] for AF). Participants with high ACEs and a favorable lifestyle had a 39 %, 40 % and 47 % lower risk of developing overall CVDs (0.61 [0.48 to 0.76]), CHD (0.60 [0.44 to 0.81], and AF (0.53 [0.36 to 0.77]) than those with high ACEs and an unfavorable lifestyle. Having a healthy lifestyle in adulthood could substantially attenuate the increased risk of overall CVDs, CHD, and AF conferred by ACEs. • Adverse childhood experiences (ACEs) independently increased the risk of incident cardiovascular diseases (CVDs). • Adopting a healthy lifestyle was significantly associated with a decreased risk of CVDs, regardless of ACEs category. • While exposure to ACEs is unmodifiable, the potential CVD risk can be significantly reduced by adopting a healthy lifestyle. [ABSTRACT FROM AUTHOR]

The arrival of one's first child is a known risk factor for mental illness, yet investigations on fathers' mental health are limited. We conducted a longitudinal investigation on paternal depression and anxiety in the nine years surrounding the transition to fatherhood. Using a national cohort of French men (CONSTANCES, n = 6299), we investigated the prevalence and associated risk factors of mental illness amongst first-time fathers. Responses to the Center for Epidemiological Studies Depression (CES-D) and 12-item General Health Questionnaire (GHQ-12) scales were used to identify clinically significant symptom scores. Self-declared mental illness was also reported by participants. Group-based modelling was used to identify latent trajectory groups for both measures. Levels of self-declared anxiety (averaging 4.9 % pre-fatherhood, 7.8 % post) exceeded that of depression (1.9 % pre- fatherhood, 3.3 % post) or other disorders. However, rates of clinically significant symptom scores (17–27 %) were consistently higher. Participants' mental health appeared to worsen from two-years prior to their child's arrival and improve from two-years after. We identified three trajectory groups for fathers' self-declared mental illness: Low stable (90.3 %); Low risk with high temporary increase (5.6 %); and Consistent high risk (4.1 %). Risk factors associated with worsening mental health trajectories were unemployment, not living with one's partner, having had adverse childhood experiences and foregoing healthcare due to financial reasons. All measures of mental illness relied on participant self-reports and are thus subject to bias. This study reveals an important period of heightened psychological vulnerability amongst first-time fathers, emphasising the need for increased and better adapted paternal mental health screening. • Anxiety appeared consistently more prevalent than depression in first-time fathers. • Fathers' mental health appeared to worsen from two-years prior to fatherhood. • Most mental illness trajectories improved two-years after the first child's arrival. • Unemployment and barriers to healthcare associated with worsening mental health • Non-resident fathers had an increased risk of negative mental health trajectories. [ABSTRACT FROM AUTHOR]

Major depressive disorder (MDD) is characterized by increased T helper (Th)1 polarization, T cell activation (e.g., CD71+ and CD40L+), and cannabinoid receptor type 2 bearing CD20+ B cells; and lower T regulatory (Treg) numbers. To delineate the effects of adverse childhood experiences (ACEs) and recurrence of illness (ROI) on activated T and CB2-bearing B populations, and Tregs, including FoxP3 + CD152+, FoxP3 + GARP+, and FoxP3 + CB1+ cells. We measured ROI, ACEs, the number of activated T cells, Tregs, and CD20 + CB2+ B cells, in 30 MDD patients and 20 healthy controls. A larger part of the variance in the depression phenome (40.8 %) was explained by increased CD20 + CB2+ and activated T cells, and lowered Tregs. ROI and lifetime suicidal behaviors were significantly and positively associated with CD20 + CB2+, CD3 + CD71+, CD3 + CD40L+, CD4 + CD71+, CD4 + CD40L+, and CD4HLADR+ numbers. ROI was significantly correlated with CD8 + CD40L+ numbers. The sum of ACEs was significantly associated with CD20 + CB2+, CD3 + CD40L+, CD4 + 40 L+ numbers, T cell activation (positively) and Treg (inversely) indices. One replicable latent vector could be extracted from activated T cells, lifetime and current suicidal behaviors, number of depressive episodes, and severity of depression, and 48.8 % of its variance was explained by ACEs. ACE-induced activation of T effector and cytotoxic cells and B cells with autoimmune potential, coupled with lowered Treg numbers are a key component of depression. The findings indicate that increasing ROI, the phenome of depression and suicidal behaviors, are caused by autoimmune processes, which are the consequence of ACEs and increasing sensitization of immune responses. • Adverse childhood experiences (ACEs) activate T effector and cytotoxic cells, B cells with autoimmune potential, and reduce Treg cell numbers. • ACE-enhanced immune-inflammatory processes are pivotal in depression. • ACEs heighten immune response, leading to autoimmunity and increased illness recurrence, the phenomenon of depression and suicidal behaviors. [ABSTRACT FROM AUTHOR]

The purpose of this study was to explore Adverse Childhood Experiences (ACEs) as a moderator between sleep duration/irregularity and overweight/obesity in U.S. adolescents. Using the National Survey of Children's Health 2017–2018 cross-sectional dataset, we included adolescents with available sleep and Body Mass Index (BMI) data. In a sample of 24,100 adolescents (mean age = 13.56 years, 49.35% female; 51% White), parents reported adolescent's sleep duration/irregularity, and number of ACEs. Logistic regression estimated the interaction between sleep duration/irregularity and the number of ACEs on overweight/obesity risk (BMI ≥ 85th percentile-for-age) using a stepwise approach and accounting for complex survey design. In the 24,100 adolescents, 33% were overweight/obese, 50% had ≥ 1 ACE, 37% slept < 8–10 h/night, and 14% had irregular sleep. Accounting for covariates and ACEs, every hour increase in sleep duration was associated with 6% decrease in overweight/obesity odds. There was a significant interaction between sleep duration and ACEs; the association between increasing sleep duration and decreasing odds of overweight/obesity was significant only in adolescents without ACEs (OR = 0.87, 95% CI [0.80, 0.95], p < 0.001). Increasing sleep duration is a recognized intervention target to decrease obesity risk, yet in adolescents experiencing ≥ 1 ACE, this protective role may be dampened. Future work may explore mechanisms for overweight/obesity development to inform interventions for adolescents facing adversity. [ABSTRACT FROM AUTHOR]

The presence of adverse childhood experiences (ACEs) in adolescents diagnosed with depression has been associated with an extensive range of mental health issues, including non-suicidal self-injury (NSSI). However, there has been a dearth of research into the prevalence of ACEs and their associations with NSSI among depressed adolescent populations in China. This study aimed to investigate the prevalence of different types of ACEs and their associations with NSSI in depressed Chinese adolescents. Utilizing Chi-squared tests, latent class analysis (LCA), and multinomial logistic regression, the prevalence of different types of ACEs and their associations with NSSI were determined in a sample of 562 adolescents with depression. Among depressed adolescents. 92.9% of depressed adolescents reported ACEs, and the prevalence of emotional neglect, physical abuse, caregiver treated violently, and bullying was relatively high. ACEs, including sexual abuse (OR = 5.645), physical abuse (OR = 3.603), emotional neglect (OR = 3.096), emotional abuse (OR = 2.701), caregiver divorce/family separation (OR = 2.5), caregiver treated violently (OR = 2.221), and caregiver substance abuser (OR = 2.117), were associated with increased odds of exposure among depressed adolescents with NSSI. The high ACEs class (19%), the moderate ACEs class (40%), and the low ACEs class (41%) were identified as latent classes. NSSI was more prevalent in the high/moderate ACEs class compared to the low ACEs class, particularly in the high ACEs class. The situation of the prevalence of ACEs among adolescents with depression was unsatisfactory, and certain types of ACEs were associated with NSSI. Eliminating potential risk factors for NSSI requires the early prevention and targeted intervention of ACEs. Moreover, additional large-scale longitudinal studies are necessary to assess the different development trajectories associated with ACEs, such as the relationships between the different development periods of ACEs and NSSI, and to ensure the adoption of evidence-based prevention and intervention strategies. [ABSTRACT FROM AUTHOR]

Although youth and adults with obsessive-compulsive disorder (OCD) endorse elevated incidence of exposure to traumatic life events during childhood, the existing literature on adverse childhood experiences (ACEs) and OCD is mixed and studies focusing on pediatric OCD are limited. The present study examines the relationship between ACEs and OCD onset, symptom severity, negative cognitive patterns, comorbidity, and cognitive-behavioral therapy (CBT) response in 142 children and adolescents with OCD. ACEs were ascertained from parent reports. Most parents reported child exposure to ACEs. Out of the parents who reported ACEs, 50% reported ACE exposure prior to OCD diagnosis and 50% reported ACE exposure after OCD diagnosis. No significant associations between ACEs and comorbidity or CBT response were found, suggesting that CBT for pediatric OCD is effective regardless of ACE exposure. Family financial problems were associated with increased obsessive-compulsive symptom severity and negative thinking. Implications for research and practice are discussed. [ABSTRACT FROM AUTHOR]

In the aftermath of the Covid pandemic and the notable rise of teen depression and anxiety (DA), there is an urgent need to focus on youth mental health. Another important variable to consider is the presence of adverse childhood experiences (ACE), which can be associated with chronic mental and physical health conditions. This pilot study explores how ACEs relate to DA for adolescents in Maui, Hawai‘i. The cohort was 75 patients seen at a Kaiser Pediatric Clinic in the spring of 2022. Data was collected from standard questionnaires and the Pediatric ACEs and Life-Events Screener (PEARLS). There were significant associations between DA and a high ACE score (4+), as well as female sex. A high ACE score can alert providers to initiate a trauma informed dialogue with patients. The effects of trauma are not often discussed at routine visits. Mental health care needs and community support can also be addressed as needed. The PEARLS questionnaire is a standard tool to help clinicians be more trauma-informed. This study explores its relevance at routine adolescent visits. [ABSTRACT FROM AUTHOR]

Limited research has examined the combined effects of psychosocial and material adversities experienced in childhood during adolescence, a sensitive period of rapid social, emotional, and cognitive development. We investigated the interaction effect of adverse childhood experiences (ACEs) and socioeconomic circumstances (SECs) during childhood on emerging self-reported depressive symptomatology among 13-year-old Portuguese adolescents. We utilized data from 4,280 participants in the Generation XXI birth cohort, collected during the baseline (2005–2006), third (2016–2017), and fourth waves (2018–2020). Adjusted odds ratios and 95% confidence intervals (CIs) were obtained from binary logistic regression analyses to estimate the likelihood of depressive symptoms based on exposure to ACEs and adverse family SECs. The interaction effect of ACEs and SECs was evaluated in terms of departure from additive and multiplicative models. Adolescents who reported experiences of abuse, school-related problems, and household dysfunction, as well as those from less advantaged family SECs at age 10, were more likely to report moderate to severe depressive symptoms at age 13, compared to their more affluent counterparts. We observed a significant additive interaction between low household income and abuse in the development of moderate to severe depressive symptoms [relative excess risk due to interaction, 0.69, 95% CI: 0.11, 1.26]. This interaction remained statistically significant on a multiplicative scale [OR = 1.61, 95% CI: 0.99, 2.69]. ACEs and low family SECs during the first decade of life are associated with an elevated risk of moderate to severe depressive symptoms in adolescence. [ABSTRACT FROM AUTHOR]

Latino/a/Hispanic adversity and adaptation literature has focused on cultural, acculturative and immigration-related stressors. Cultural and social strengths, key Latino/a/Hispanic features, and their concurrence, remain qualitatively underexplored. To enhance intervention and prevention, research understanding experiences of Latino/a/Hispanic youth adaptation representing three generations is needed. Forty participants participated in semi-structured interviews detailing adversity, cultural strengths and support during their youth. Thematic analysis approach guided coding of transcripts. Three coders met regularly to discuss and resolve differences, identifying emergent themes. The sample included 24 females and 16 males (M age = 27.9) characterizing three generations (first n = 15; second n = 14; third+ n = 11). Three main themes emerged: (1) perceived adversity, described discrimination, and related adversities; (2) cultural adaptation, adjustment, and the shaping of bicultural identities; and (3) supportive and formative relationships buffering adversity. Themes illustrated adversity and cultural strengths within Latino/a/Hispanic protective relationships and contexts. Findings inform policies that support Latino/a/Hispanic youth and family engagement and intervention approaches. [ABSTRACT FROM AUTHOR]

This study aimed to investigate the prevalence and correlates of attention deficit hyperactivity disorder (ADHD) and its subtypes in Chinese community adults. A total of 7366 adults (mean age = 38.13 years, SD = 7.87, ranging from 18 to 81) completed questionnaires assessing childhood positive experiences, childhood trauma, behavior inhibition, aggression, suicide behaviors, and ADHD symptoms. Logistic regression was conducted to examine the correlations. Multivariate analysis of variance was used to compare the differences in aggressive behaviors between different ADHD subtypes. The prevalence of ADHD was 6.7%, with the inattentive type (ADHD-I) 4.6%, the hyperactive-impulsive type (ADHD-H) 0.8%, and the combined type (ADHD-C) 1.3%. Younger age, low income, poorer physical condition, fewer childhood positive experiences, childhood trauma, and behavior inhibition were significantly related to ADHD symptoms. Regarding ADHD subtypes, young age, low income, less childhood positive experience, childhood trauma and behavior inhibition were related to elevated risk for ADHD-I; poorer physical condition and childhood trauma were significantly related to ADHD-H; childhood trauma and behavior inhibition were significantly associated with ADHD-C. Finally, all subtypes were associated with aggression behaviors, non-suicide self-injury and suicidal behaviors, with ADHD-HI and ADHD-C reporting more aggressive behaviors and suicide attempt. The findings suggest that adult ADHD is a common disorder with high prevalence in the Chinese community population, and multiple psychosocial factors are related to ADHD. Although most adults with ADHD endorsed inattention symptoms, ADHD with hyperactive-impulsive symptoms need more attention in consideration of its related high aggressive behaviors and risk of suicidal attempt. [ABSTRACT FROM AUTHOR]

Background: The current study was aimed at constructing a questionnaire for evaluating the role of variant environmental factors on language acquisition in the three surrounding levels of communication that include familial level, preschool or nursery level, and surrounding social environmental level among children with delayed language development (DLD) due to environmental deprivation. The current study was a retrospective case–control study that was performed on 100 Egyptian Arabic-speaking children aged from 2 to 5 years. The study was carried out among preschool age children in the Mansoura governmental and private preschools (53 males and 47 females). They were divided into 2 groups: Group I (case group) consisted of 50 children with DLD due to environmental deprivation, and group II (control group) consisted of 50 typically developed children. Results: The present study demonstrated several factors for prediction of DLD due to environmental deprivation. Univariable analysis revealed multiple factors as number of hours that parents present at home, time of the mother's job, the relation between the child and the mother, the parents select certain time to talk and play with their child, joint attention of the mother, mother asking her child what he wants, long time using multimedia, divorce as a traumatic stress, bad social performance, and low socioeconomic status. Multivariate analysis revealed that longer time of the mother's job and less time the mother select to talk and play with her child were the environmental deprivation factors which had the most precipitating effect on predicting DLD. Conclusions: The constructed Arabic questionnaire was proved to be valid, reliable, and homogenous and is likely to produce consistent responses in evaluating the variant environmental factors on language development among children with DLD due to environmental deprivation in the three surrounding communications levels. [ABSTRACT FROM AUTHOR]

Adverse childhood experiences (ACEs) -- potentially traumatizing events that occur in childhood -- have been linked to serious health problems later in life. Despite the documented negative effects of ACEs, and the high prevalence of ACEs in lower-middle-income countries, research about ACE prevalence is sparse for locales in Sub-Saharan Africa. This descriptive study examined the prevalence of ACEs among 800 children and teens in the Cape Coast Metropolis, Ghana, as reported by their parents (or caregivers), who were recruited from February to April 2021. Parent-reported sociodemographic characteristics and ACEs experienced by the children and teens were collected with the Center for Youth Wellness ACE Questionnaire (CYW ACE-Q). Analysis of the parents' reports indicated that about 84.9% of the children and teens had been exposed to at least one ACE, 69.1% had experienced two or more ACEs, and 51.8% had experienced three or more ACEs. The most prevalent ACEs, according to the parents, were community violence (50.2%), separated parents (34.0%), physical abuse (33.4%), and emotional abuse (28.9%). This study thus reveals a high prevalence of ACEs in the Cape Coast Metropolis of Ghana, suggesting the need for policies and actions aimed at reducing community violence and protecting children from abuse in the Metropolis. [ABSTRACT FROM AUTHOR]

Purpose: While associations between adverse childhood experiences (ACEs) and intimate partner violence (IPV) have been well-documented, few studies have identified relationship factors that buffer this association. Even fewer studies have examined these relationships among Latino sexual minority men (SMM). To address this gap, we tested a model in which relationship functioning moderated this association in a sample of Latino SMM couples. Methods: Data were collected from 95 couples (190 participants) using a sequential index-partner recruitment design. Actor-Partner Interdependence Models were calculated using generalized estimating equations (GEE). Results: Among men whose partners scored low on the Revised Dyadic Adjustment Scale, those who reported 1 or more ACEs reported more forms of IPV victimization. In contrast, the association between the actor effect of ACEs and IPV victimization was not significant among those whose partners scored high on the Dyadic Adjustment Scale. In a symmetrical pattern, among men who scored low on the Dyadic Adjustment Scale those whose partners reported 1 or more ACEs reported more forms of IPV victimization; however, at high levels of self-reported relationship functioning, partner reported ACEs were relatively associated with fewer reported forms of IPV victimization. Conclusions: These results are consistent with the premise that relationship functioning may serve as one source of resilience, attenuating the association between ACEs and IPV victimization among a sample of coupled Latino SMM. We interpret these findings within the larger IPV literature and provide suggestions for IPV prevention program development, with a particular emphasis on reaching Latino SMM. [ABSTRACT FROM AUTHOR]

Objective: The term psychotic experiences (PEs) encompass subclinical hallucinatory and delusional experiences. There are limited number of studies on PEs clinical and socio-demographic characteristics. We aimed to investigate the association between PEs and patterns of cannabis use, cognitive functions, schizotypy and childhood traumas. Methods: Participants were recruited from specialized units using the snowball method. All of the participants were regular cannabis users. Participants with PEs and without PEs were compared by looking into socio-demographic and clinical correlates. Significant variables at univariate comparisons were included in binary multivariate logistic regression analysis with PEs as the dependent variable. Results: Forty participants were recruited (20 with PEs, 20 without PEs). Adolescence onset of cannabis use (χ2 = 8.120; p < 0.05), positive schizotypy (t = 3.762; p < 0.01), Trail Making Test A (TMT A) Scores (u = 98.5; p < 0.01) and emotional neglect (u = 128; p = 0.05) were significantly associated with PEs. The binary regression model included a significant contribution of positive schizotypy (OR = 1.16, CI 1.025–1.330) and TMT A Score (OR = 1.22, CI 1.03–1.44). Conclusions: Results showed a novel positive association of PEs with adolescent-onset cannabis use, TMT A Scores, positive schizotypy and emotional neglect. PEs were predicted independently by positive schizotypy and TMT A Scores. [ABSTRACT FROM AUTHOR]

As compared to adult populations, there is a significant dearth of studies examining official misconduct among juveniles, leaving important gaps in our knowledge. Utilizing a sample of youth completing juvenile justice residential placement in Florida across four fiscal years (n = 5739), the current study seeks to examine the joint effects of facility environment and individual characteristics on institutional misconduct, represented by aggression and academic misconduct in facilities. Academic Youths' severity of criminal involvement, adverse childhood experiences (ACEs), emotional and communication skills, and history of violence or drugs all contributed to explaining their aggression and academic misconduct in facilities. The level of institutional security consistently emerged as a significant predictor for academic misconduct and aggression. Aggression in facilities was more sensitive to the severity of ACEs. Policy implications and limitations are discussed. [ABSTRACT FROM AUTHOR]

Quality relationships among families and teachers in early care and education (ECE) hold promise to nurture resilience among children impacted by adversity. However, little is known about how adverse childhood experiences (ACEs) may affect the interactions between families and teachers. This study uses quantitative survey data from families (N = 235) and qualitative interview data from teachers (N = 13) to examine the link between children's adversity and family-teacher relationship quality (knowledge, attitudes, practices) in ECE. Quantitative results indicate that when a child has experienced more of the ACEs conventionally studied (e.g. maltreatment, parent substance abuse or mental illness), parents are more likely to perceive lower quality practices with teachers, but when a child has experienced more ACEs on an extended measure (e.g., bullying, discrimination), parents are more likely to perceive higher quality practices with teachers. Qualitative results indicate that teachers report challenges in relationships with families when children experience trauma or adversity, but that ACEs also can present an opportunity to strengthen family-teacher relationships. Findings can inform professional development for teachers focused on strategies to work with families facing adversity, as well as policies related to program standards (e.g., family engagement) and interventions to improve family-teacher relationships quality. [ABSTRACT FROM AUTHOR]

Intimate partner violence (IPV) is a serious social and public health problem in the United States. Adverse childhood experiences (ACEs) and poor mental health are associated with IPV. Sexual minority men (SMM) experience each of these disproportionately; however, limited studies have examined the interrelationships of these variables among SMM. Cross-sectional data from the first wave (September 1, 2020–April 25, 2021) of the National Couples' Health and Time Study were used to assess the prevalence of physical, sexual, and psychological IPV victimization and perpetration and the association with ACEs and depression, anxiety, and stress among cisgender men in same-gender and different-gender relationships. Log-binomial regression was used to evaluate relationships, stratified by couples' gender identity. In a sample of 1,681 men, including 689 sexual minority men, 40.6% reported IPV victimization and 33.1% reported IPV perpetration. Stratified by couples' gender identity, victimization and perpetration were reported more frequently among men in different-gender relationships compared to men in same-gender relationships (40.7% vs. 33.9%; 33.2% vs. 30.2%). Psychological victimization and perpetration were the most commonly reported. Among men in same-gender relationships, depression symptoms had the highest association with IPV victimization (prevalence ratio [PR] = 2.14, 95% confidence interval [CI]: 1.56–2.95) and perpetration (PR = 1.72, 95% CI: 1.24–2.39). Research, clinical screenings, and other settings that focus on understanding and intervening on partner violence victimization and perpetration should intentionally consider the experiences of SMM in order to effectively promote healthy relationships and optimal mental health. [ABSTRACT FROM AUTHOR]

Background Objectives Methods Results Conclusions Exposure to trauma across the life course may be associated with cardio‐metabolic dysfunction during pregnancy; however, previous research has been inconsistent, particularly in highly exposed populations.To estimate associations between types and timing (first occurrence) of trauma exposure and hypertension experienced during pregnancy in a safety‐net hospital in Atlanta, Georgia, 2011–2022.Participants completed a 14‐item trauma screener. We linked that information to data from the medical record on hypertension (including chronic hypertension, gestational hypertension or preeclampsia). We fit logistic regression models and used the estimates to calculate risk ratios for each trauma type and each critical window (0–9 years, 10–19 and 20+). We fit unadjusted models and adjusted for age, parity and education.We included 704 individuals with a delivery within 12 months following screening. The majority (94%, 661) reported at least one traumatic event, most commonly witnessing violence (79.4%). Overall, 18% experienced gestational hypertension, 10.8% chronic hypertension and 11.9% preeclampsia. Among individuals who reported trauma, 31.5% screened positive for probable posttraumatic stress disorder and 30.9% for probable depression, compared to 0 and 2.3% among those without reported trauma. No trauma type (violence, witnessing violence, non‐interpersonal or sexual assault) was associated with increased hypertensive risk, regardless of timing.In this sample with a high trauma and hypertension burden, trauma was not associated with an elevated risk of hypertension during pregnancy, despite a high burden of PTSD and depressive symptoms among people with trauma exposure. [ABSTRACT FROM AUTHOR]

Background: Incorporating genomic data into risk prediction has become an increasingly popular approach for rapid identification of individuals most at risk for complex disorders such as PTSD. Our goal was to develop and validate Methylation Risk Scores (MRS) using machine learning to distinguish individuals who have PTSD from those who do not. Methods: Elastic Net was used to develop three risk score models using a discovery dataset (n = 1226; 314 cases, 912 controls) comprised of 5 diverse cohorts with available blood-derived DNA methylation (DNAm) measured on the Illumina Epic BeadChip. The first risk score, exposure and methylation risk score (eMRS) used cumulative and childhood trauma exposure and DNAm variables; the second, methylation-only risk score (MoRS) was based solely on DNAm data; the third, methylation-only risk scores with adjusted exposure variables (MoRSAE) utilized DNAm data adjusted for the two exposure variables. The potential of these risk scores to predict future PTSD based on pre-deployment data was also assessed. External validation of risk scores was conducted in four independent cohorts. Results: The eMRS model showed the highest accuracy (92%), precision (91%), recall (87%), and f1-score (89%) in classifying PTSD using 3730 features. While still highly accurate, the MoRS (accuracy = 89%) using 3728 features and MoRSAE (accuracy = 84%) using 4150 features showed a decline in classification power. eMRS significantly predicted PTSD in one of the four independent cohorts, the BEAR cohort (beta = 0.6839, p=0.006), but not in the remaining three cohorts. Pre-deployment risk scores from all models (eMRS, beta = 1.92; MoRS, beta = 1.99 and MoRSAE, beta = 1.77) displayed a significant (p < 0.001) predictive power for post-deployment PTSD. Conclusion: The inclusion of exposure variables adds to the predictive power of MRS. Classification-based MRS may be useful in predicting risk of future PTSD in populations with anticipated trauma exposure. As more data become available, including additional molecular, environmental, and psychosocial factors in these scores may enhance their accuracy in predicting PTSD and, relatedly, improve their performance in independent cohorts. [ABSTRACT FROM AUTHOR]

Background: Limited data exists on trends in prevalence of adverse childhood experiences (ACE) at the national level and sociodemographic correlates of having ACEs. This study examined trends in ACE prevalence and sociodemographic correlates in US adults over 14 years using nationally representative data. Methods: Data on 447,162 adults from the Behavioral Risk Factor Surveillance System (BRFSS) across four timepoints (2009–2010; 2011–2012; 2019–2020; 2021–2022) was analyzed and weighted for population estimates. The primary outcome was ACEs with 3 groups used (0 vs. 1 + ACEs; <4 vs. 4 + ACEs; 0 vs. 1 vs. 2 vs. 3 vs. 4 + ACEs). Sociodemographic factors included age, sex, race/ethnicity, employment, education, marital status, income and insurance status. Prevalence trends were examined by estimating prevalence of ACE groupings (0/1+; <4/4+; 0,1,2,3,4+) across the four timepoints and trend analysis was performed to determine if the differences over time were statistically significant. Unadjusted and adjusted prevalence ratios were estimated using log-binomial regression models with ACE groupings as the outcome and timepoints as the primary independent variable with sociodemographic factors as covariates. Results: Across the four time points, prevalence of ACEs was higher across groupings of ACEs by time. For ACEs 1+, prevalence was 62.2% (2009–2010); 62.2% (2011–2012); 64.5% (2019–2020); and 67.2% (2021–2022). For ACEs 4+, prevalence was 17.4% (2009–2010); 18.1% (2011–2012); 20.4% (2019–2020); and 22.6% (2021–2022). Prevalence of ACE 1 + was higher for older adults, Non-Hispanic Black adults, Non-Hispanic Other adults, and those with higher education. Prevalence of 4 + ACEs was higher for females, and lower for those with higher education and those with higher annual incomes. Conclusion: This study shows an increased prevalence of having ACEs over a 14-year period and identified independent sociodemographic correlates of having ACEs in a nationally representative study. Targeted interventions are needed to reduce burden of ACEs using population-based approaches. [ABSTRACT FROM AUTHOR]

This study aimed to investigate the associations of childhood trauma and its facets with depressive symptoms in depressed adolescents during the post COVID-19 epidemic, and explore the potential mediating role of social peer rejection in these associations. A total of 413 adolescents with depressive disorders completed the Chinese version of the Child Trauma Questionnaire Short Form, the Social Peer Rejection, and the Children’s Depression Inventory. Childhood trauma (β = 0.42, p < 0.01) and social peer rejection (β = 0.18, p < 0.01) were positively related to depressive symptoms, after adjustment for demographic factors. Furthermore, social peer rejection partly mediated the relationship between childhood trauma and depressive symptoms, and the mediation effect ratio was 17.0% (p < 0.001). This study found that childhood trauma and social peer rejection are both risk factors for depressive symptoms, and social peer rejection played a mediating role in the relationship between childhood trauma and depressive symptoms. [ABSTRACT FROM AUTHOR]

This study explores the impact of life course socioeconomic status (SES) and childhood trauma on depressive symptoms in Chinese middle-aged and older adults, while also examining the role of chronic diseases and implications for social work practice. Using data from 9,942 participants, structural equation was established to investigate these relationships. Results reveals that low childhood SES positively affects depressive symptoms through low SES in mid-to-late life (std. β = 0.168, p < .001), and domestic child abuse negatively impacts depressive symptoms through low SES in mid-to-late life (std. β=-0.020, p < .001). Additionally, experiencing peer bullying is directly associated with depressive symptoms (std. β = 0.145, p < .001). Exposure to domestic violence is directly related to depressive symptoms (std. β = 0.078, p < .001) and indirectly leads to more severe depressive symptoms through chronic disease (std. β = 0.023, p < .001). Social workers in healthcare settings can utilize these findings to better understand risk factors for depression and provide trauma-informed care and economic assistance across the life course. Additional training for social workers on the lasting impacts of childhood adversity is warranted. By intervening at both individual and policy levels, social work practitioners can help break cycles of poverty and poor health stemming from childhood. [ABSTRACT FROM AUTHOR]

It is well established that the exposure to adverse childhood experiences (ACEs) may alter the the development of personality. Nevertheless, only a part of individuals exposed to ACEs actually develop Personality Disorders (PDs). According to the alternative model of PDs, impairments in dimensional self-aspects, i.e., Identity and Self-direction (SD), may represent potential candidates to promote the transition from ACEs to PDs. We analysed patients' data from the A.T. Beck Institute of Rome (n = 626) to evaluate the ACEs and SD interplay in PDs patients using Cloninger's Self-Directedness to assess their SD. First, we explored the presence of ACEs in patients affected by PDs. Secondly, we examined the association between ACEs and SD and subsequently how SD influences the severity of the PDs. Finally, since SD and ACEs were both associated to PDs, we wondered if SD could mediate the relationships between ACEs and PDs. Results evidenced a partial competitive mediation effect of SD on the relationship between child abuse and neglect and the number of PDs. In agreement with the AMPD, Self-functioning dimension may represent a main target for psychotherapeutic intervention. [ABSTRACT FROM AUTHOR]

Recent research has primarily focused on elucidating the role of specific cognitive vulnerability factors in the intricate relationship between childhood trauma and depression. To advance existing research by integrating two prominent cognitive theories of depression (the Beck's cognitive theory and hopelessness theory), this study proposed a moderated mediation model aimed at investigating the mediating role of the sense of control and the moderating effect of rumination in this complex association. A sample of 1,091 college students (comprising 436 males; age range 17–25) was recruited through poster advertisements and a snowball sampling approach. Participants voluntarily engaged in the study and completed a battery of assessments, including measures of depression, childhood trauma, sense of control, and rumination. Our findings suggest that childhood trauma affects depression not only directly but also indirectly through the mediating influence of the sense of control. Furthermore, the result reveals that the mediating role of the sense of control is moderated by the intensity of rumination. Specifically, this mediating effect is more pronounced among college students with higher levels of rumination. The outcomes of this investigation provide prospective empirical support, suggesting that the loss of control and rumination may serve as viable targets for preventative and interventional measures in addressing depression among individuals who have experienced childhood trauma. This research enhances our understanding of the intricate interplay between cognitive determinants and depression, informing future research in this critical domain of mental health. [ABSTRACT FROM AUTHOR]

This study explored Adverse Childhood Experiences (ACEs) in relation to the COVID-19 pandemic using YRBSS survey data on youth grades 9–12 and was analyzed using weighted sample prevalence, univariant weighted analysis, and multivariable weighted logistic regressions. Models adjusted for age, sex, ethnicity, race, sexual identity, smoking, alcohol, and illicit drug use. Inclusion criteria were those aged 14 years or older. Results showed decreased violence, substance use, and sexual health risk in 2021 compared to 2019, but increased mental health risk. Black individuals had higher odds of violence and victimization and sexual health risk. Gay, lesbian, and bisexual youths faced increased odds of various risks (p < .05). Understanding ACEs post-COVID-19 is crucial for mitigating their long-term effects on health. [ABSTRACT FROM AUTHOR]

Caregiver trust in medical providers and the healthcare system is essential to pediatric primary care. Relatively little research has been conducted on contributors to caregivers’ trust, or lack thereof, in aspects of pediatric primary care, especially for those who have experienced adversity. To examine the relationship between caregiver trust and adverse childhood experiences (ACEs) in pediatric primary care, we measured four aspects of trust in 76 caregivers (74 mothers, 2 aunts) of children at an urban primary care clinic. We ran correlation and regression analyses to examine the relationship between the Philadelphia ACEs and caregiver trust. Results indicated that specific ACEs (e.g. experiencing abuse) were associated with caregiver mistrust in the healthcare system and lower trust in the child’s pediatrician. Some ACEs (e.g. community discrimination) were associated with only general trust. Thus, the relationship between trust and trauma varied based on the levels of trust and types of ACEs. [ABSTRACT FROM AUTHOR]

This article explores the opportunities for client and therapist when somatic therapies and psychotherapy are brought together. Through a case study I illustrate how understandings and interventions from Intersubjective Self Psychology, Somatic Experiencing®, and Integral Somatic Psychology™ all supported the client’s emergence from profoundly somatised childhood traumatic loss, allowing them to restore thwarted developmental processes, rebuild affect tolerance, process their grief, and inhabit their life in new ways. I explicate how a deeply embodied psychotherapeutic relationship, where the conversations between the client and therapist’s bodies are held at the centre of the therapeutic relationship, can support reducing client re-traumatisation in therapy, meet early developmental needs, re-link affective layers allowing somatic and psychological (re)integration. I also explore the impact on, and possibilities for, the therapist of combining somatics and psychotherapeutic principles and techniques. [ABSTRACT FROM AUTHOR]

Background: Community violence exposure (CVE) in adolescence is associated with poorer mental health although the situational factors that may impact on this relationship remain relatively unexplored. The present study aimed to investigate if the degree of perceived stress during CVE has an effect on future posttraumatic stress disorder (PTSD) symptoms in youth, and if this association differs between females and males. Methods: Data were analyzed from 760 U.S. adolescents (mean age = 14.00 years), who participated in two surveys, one year apart. Information about CVE (witnessing violence and violence victimization) and the stress severity associated with it was collected in the first survey, whereas data on PTSD symptoms were obtained in the second survey. Generalized Linear Models were used to examine the associations that were also adjusted for ethnicity, age and socioeconomic status. Results: The results showed a longitudinal association between CVE-related stress and future PTSD symptoms, with students who had higher levels of perceived stress during CVE (witnessing or victimization) reporting higher PTSD symptom levels subsequently. There was no interaction between sex and CVE-related stress and PTSD symptoms, although females reported more PTSD symptoms. Conclusions: The severity of the perceived stress associated with CVE should be regarded as a potentially important prognostic factor for identifying those who might develop PTSD symptoms after CVE and this may facilitate early intervention and treatment for those exposed to community violence. [ABSTRACT FROM AUTHOR]

Trauma is an extreme event that offers us clues about individual differences in cognitive processes, including the development and maintenance of cognitive biases such as exaggerated probability estimates toward future traumatic events. The current study investigated probability estimate biases toward future traumatic events in 445 undergraduate students (93.9% Hispanic) who experienced one of the following traumatic events or no trauma: childhood interpersonal trauma, adult interpersonal trauma, accident, a family member's death due to COVID-19, or no trauma. Participants completed online questionnaires assessing probability estimates for two types of future traumas (interpersonal violence traumas and accidental traumas) and posttraumatic stress symptoms. The childhood trauma group generally showed the strongest probability estimate biases for future traumatic events among the four trauma-exposed groups. Similarly elevated probability estimates for future traumatic events were found in the other three trauma-exposed groups. Limited associations between levels of posttraumatic stress symptoms and probability estimate biases for future traumatic events were found. This study was the first to reveal the presence of biased probability estimates for future traumatic events in Hispanics exposed to a traumatic event. The results suggest that probability estimation biases developed in response to a specific traumatic event might become generalized to other types of traumatic events. [ABSTRACT FROM AUTHOR]

Background: Adverse childhood experiences (ACEs) are known to be associated with depression. However, the extent to which such association varies by age at the first occurrence of ACEs remains unexplored. The objectives of this study are: (1) To describe the association between ACEs and depression among university students in China, and; (2) to assess the extent to which the mentioned association varied by age at first ACE. Methods: We conducted a self-administered survey among university students in southern China and analyzed the data using descriptive statistics and multivariate logistic regression. Results: We found significant associations between ACEs and depression prevalence, particularly when comparing students with three or more ACEs vs. students with no ACEs (62% vs. 36%; Adjusted OR = 3.49; 95% CI = 1.99, 6.12). Stratified analyses showed that the association was particularly strong among students who first experienced ACEs at age 0–6 years (66% vs. 36%; Adjusted OR = 4.05; 95% CI = 1.90, 8.59), but was non-significant among those who first experienced ACEs at age 13–18 years (31% vs. 36%; Adjusted OR = 0.99; 95 CI = 0.24, 4.08). Conclusion: The strength of the associations between ACEs and depression varied by the age at first ACE. However, the cross-sectional study design, potential information bias, and lack of generalizability should be considered as caveats in the interpretation of the study findings. [ABSTRACT FROM AUTHOR]

Objective: This study explored the influence of the life course on mental health by identifying key trends, seminal works, and themes in existing research. Additionally, it highlights the major discussions at the intersection of life course and mental health. Methods: Documents were extracted from the Web of Science Core Collection (WoSCC), to systematically analyze themes on mental health outcomes across the life course. The analysis was based on key bibliometric tools, including VOSviewer 1.6.11, R Studio software, and GraphPad Prism 9 to analyze the evolution and impact of scholarly contributions in this domain. Results: The accumulated body of research concerning the life course's impact on mental health, which began to emerge around 1990 displayed a consistently upward trend. Predominant contributions originate from developed nations and frequently look into the psychosocial determinants of mental health over life course. Life course and mental health studies have been extensively infused with biopsychosocial frameworks that consider the role of genetic makeup, neurodevelopment, cognition, affect, sociocultural dynamics, and interpersonal relationships. Life course theory application in mental health highlight the substantive effects of accumulated adversities, notably social determinants of health, adverse childhood experiences (ACEs), and their implications for subsequent mental health outcomes. Conclusion: The nexus of life course and mental health outcomes demands further scholarly interrogation, particularly within underserved regions, to strengthen protective mechanisms for vulnerable populations. [ABSTRACT FROM AUTHOR]

BACKGROUND: Screening for adverse childhood experiences (ACEs) and resilience in pregnancy is a promising practice for mitigating ACEs-related health complications. Yet, the best follow-up for pregnant patients with high ACEs and/or low resilience has not been established. OBJECTIVE: This study evaluates referrals to and participation in an embedded health psychologist (EHP) intervention for pregnant patients with ACEs and/or low resilience. MATERIALS AND METHODS: Patients in 3 Kaiser Permanente Northern California medical centers with ACEs who had also received resilience screening during standard prenatal care and who were participating in an EHP intervention were included (N = 910). The authors used multivariable logistic regression to examine whether ACEs (0, 1-2, 3+) and resilience (high vs low) were associated with referrals to and participation in EHP intervention. They also evaluated the impact of EHP intervention through clinician (N = 53) and patient (N = 51) surveys. RESULTS: Patients with 3+ vs 0 ACEs were more likely to receive an EHP referral (adjusted odds ratio [aOR] = 2.89, 95% confidence interval [CI]: 1.93-4.33) and were more likely to participate in EHP intervention (aOR = 2.85, 95% CI: 1.87-4.36). Those with low vs high resilience were also more likely to receive an EHP referral (aOR = 1.86, 95% CI: 1.32-2.62) and participate in EHP (aOR = 1.71, 95% CI: 1.19-2.44). When ACEs and resilience were combined, those with high ACEs and low resilience had the greatest odds of referrals and participation. Patients and clinicians reported positive experiences with EHP intervention. CONCLUSION: Patients with higher ACEs and lower resilience scores were more likely to be referred to and participate in EHP intervention, suggesting that at-risk patients can be successfully linked with a health psychologist when accessible within obstetric care. [ABSTRACT FROM AUTHOR]

Adverse childhood experiences (ACEs) confer significant risk for diabetes in adulthood. The purpose of this study was to explore perceptions about risk, potential pathways leading to diabetes, and solutions based on the lived experience. Three focus groups were conducted. A semi-structured interview guide was used to explore prevalence and causes of ACEs, pathways to diabetes, and possible solutions. Grounded theory was used for analysis. Constant comparisons resulted in emergent themes that were indexed and compared with the rest of the data to establish analytical categories. Analytical categories were further refined as additional data was collected until groups of key themes or categories were identified and used to construct a theoretical framework. Participants totaled 23 across 3 groups. All participants were African American. Average age was 49, average number of years living with diabetes was 13 years. Participants included both men and women. Participants experienced one or more occasions of sexual abuse, physical and verbal abuse, and neglect. The major themes can be classified as A. Cause, B. Pathway, and C. Treatment/solution. Findings may not generalize to the overall population with ACEs and diabetes. Three major themes were identified: family instability and financial hardship as risks for ACEs, maladaptive coping leading to diabetes, and social structure as a potential solution. Future research is needed to examine quantitatively, pathways to inform prevention at the primary, secondary, and tertiary levels of care for both the prevention of ACEs, mitigating risk for diabetes, and improving overall health. • Adverse Childhood Experiences (ACEs) confer significant risk for diabetes in adulthood. • Limited work has been done to contextualize the relationship between ACEs and diabetes. • From a patient perspective, family instability and financial hardship are risks for ACEs. • Maladaptive coping may be the mechanism through which diabetes develops. • Emphasis on the social structure was identified as a key solution. [ABSTRACT FROM AUTHOR]

We aimed to examine whether positive and negative coping styles mediated the influences of childhood trauma on NSSI or depressive severity in adolescents with major depressive disorder (MDD). The Children's Depression Inventory (CDI), the Ottawa Self-Injury Inventory Chinese Revised Edition (OSIC), the short-form Childhood Trauma Questionnaire (CTQ-SF), and the Simplified Coping Style Questionnaire (SCSQ) were evaluated in 313 adolescents with MDD. MDD adolescents with NSSI had higher CTQ-SF total score, emotional and sexual abuse subscale scores, but lower CDI total and subscale scores compared to the patients without NSSI. The multiple linear regression analysis revealed that emotional abuse (β = 0.075, 95 % CI: 0.042–0.107) and ineffectiveness (β = −0.084, 95 % CI: −0.160 ∼ −0.009) were significantly associated with the frequency of NSSI in adolescents with MDD, but emotional abuse (β = 0.884, 95 % CI: 0.570–1.197), sexual abuse (β = 0.825, 95 % CI: 0.527–1.124) and negative coping style (β = 0.370, 95 % CI: 0.036–0.704) were independently associated with the depressive severity in these adolescents. Furthermore, the mediation analysis demonstrated that positive coping style partially mediates the effect of childhood trauma on NSSI (Indirect effect = 0.002, 95 % bootCI: 0.001–0.004), while the negative coping style partially mediates the relationship between childhood trauma and depressive severity (Indirect effect = 0.024, 95 % bootCI: 0.005–0.051) in adolescents with MDD. A cross-sectional design, the retrospective self-reported data, the small sample size. Our findings suggest that coping styles may serve as mediators on the path from childhood trauma to NSSI or depressive severity in MDD adolescents. • Adolescent depressive patients with nonsuicidal self-injury (NSSI) had higher level of childhood maltreatment compared to patients without. • Childhood maltreatment is positively correlated to the NSSI and depressive severity in adolescents with major depressive disorder. • The coping style can mediate the effect of childhood trauma on NSSI and depressive severity in depressive adolescents. [ABSTRACT FROM AUTHOR]

The shortage of adequately trained healthcare providers (HCPs) able to treat adults who have experienced childhood interpersonal trauma (CIT) is a pressing concern. This study explored HCPs’ training needs for a trauma-focused psychoeducational group intervention and the potential barriers and facilitators to accessing such training. Three 1-hour focus group sessions were conducted with HCPs (n = 17) from two urban and one rural community healthcare organization serving diverse populations in Ontario, Canada, including under-housed people, women struggling with mental health and addiction, and LGBTQ+ populations. On average, participants had 2.4 years in their current role and 18.1 years of mental health field experience. Thematic analysis revealed key findings: a strong clinical need for trauma services, accessible training programs, and broadly applicable interventions relevant for diverse populations. Notably, participants emphasized the clinical advantages and increased accessibility of a virtual training programs focused on psychoeducational treatment interventions, particularly within community-based healthcare settings. This study highlights the potential of a virtual psychoeducational training programs for HCPs to address this critical gap in healthcare provision for individual with CIT. It also underscores the need to move beyond training program development and focus on implementation and sustainability of interventions in clinical practice. [ABSTRACT FROM AUTHOR]

Background: Childhood trauma history has frequently been linked to eating disorders (EDs); nevertheless, the scientific literature calls for extending knowledge regarding mediators between EDs and childhood trauma. This study explored whether ED symptoms and early maladaptive schemas were more severe in ED patients with severe childhood trauma than in ED patients with no/mild childhood trauma and whether early maladaptive schemas mediated the relationship between childhood trauma and ED symptom severity. Methods: Data were extracted from the Regional Centre for Eating Disorders registry at the University Hospital of Verona. The extracted data included self-reported data, including the Eating Disorder Inventory-3 score, Young Schema Questionnaire score, Childhood Experience and Experience of Care and Abuse Questionnaire score, and sociodemographic and clinical information on the ED outpatients seeking care. A mediation analysis using the structural equation modeling procedure was conducted. Results: Forty-two outpatients, 31% of whom exhibited severe childhood trauma, satisfied the criteria for registry data extraction. The severity of ED symptoms, as well as the early maladaptive schemas' scores for emotional deprivation, defectiveness, failure, vulnerability, insufficient self-control, and negativity, were greater in ED outpatients with severe childhood trauma. Furthermore, early maladaptive schemas related to defectiveness, failure, and negativity had a mediating role in the relationship between severe childhood trauma and ED symptom severity. Conclusions: This exploratory study provides preliminary evidence about the importance of early maladaptive schemas in the relationship between trauma history and ED psychopathology. In addition, ED symptoms may represent a dysfunctional attempt to avoid unpleasant emotions associated with schema activation. The results support the need to consider early maladaptive schemas in the treatment of traumatized patients with ED symptoms. Study limitations, research and clinical implications are discussed. Plain English summary: Eating disorder psychopathology was found to be related to a history of trauma. Nonetheless, our understanding of the mediators of the relationship between childhood trauma and eating disorders remains to be improved. The current study revealed that certain early maladaptive schemas (i.e., defectiveness, failure, and negativity) mediated the relationship between childhood trauma and eating disorder symptoms and that outpatients who experienced severe childhood trauma reported more severe eating disorder symptoms and greater severity of certain early maladaptive schemas, such as emotional deprivation, defectiveness, failure, vulnerability, insufficient self-control, and negativity. Our findings support the need to consider early maladaptive schemas in the treatment of traumatized patients with eating disorders. [ABSTRACT FROM AUTHOR]

In response to communities where individuals experience both disproportionate numbers of Adverse childhood experiences (ACEs) and other health inequities, narrative change has emerged as a powerful tool to change how ACEs are viewed and addressed by communities. The special issue presents a set of papers examining efforts to use narrative change to address ACEs. In this commentary, we offer reflections on the introduction and three articles of the special issue and point to future considerations for implementation and impact of community narrative initiatives. For example, we assert that to prevent and address the outcomes of ACEs such as substance use and mental health problems, communities need to include and amplify the voices of those with lived experience during decision‐making about policy. We also espouse using research models of resilience in communities as a way to further uptake of narrative change strategies in the literature on ACEs and health disparities in communities. Using trauma‐informed outcomes and measures are also critical to measure how narrative change can move the needle to promote health equity. [ABSTRACT FROM AUTHOR]

Background: Sleep problems are common in early childhood and may be affected by parental adverse childhood experiences (ACEs). However, few studies have examined the longitudinal effect of parental ACEs on offspring sleep problems and the underlying mechanism. This study examined parents' psychological distress and harsh discipline (psychological aggression and corporal punishment) as mediators in the longitudinal pathway from parental ACEs to offspring sleep problems. Methods: The participants included 617 3-year-old children (mean age of 43.13 months, SD = 3.82) and their parents (mean age of 33.24 years, SD = 4.01) from Wuhu, China. The participants completed an online questionnaire on ACEs, psychological distress, and demographic characteristics in September 2022 (Time 1). Parents completed another online questionnaire in September 2023 (Time 2) on harsh discipline and offspring sleep problems. A path model was used to examine the associations. Results: Parental ACEs did not directly predict offspring sleep problems. Psychological distress (β = 0.041, 95% CI [0.005, 0.111]) and harsh discipline in the form of psychological aggression (β = 0.019, 95% CI [0.006, 0.056]) separately mediated the relationship between parental ACEs and offspring sleep problems. Psychological distress and psychological aggression also played a serial mediating role in the association of parental ACEs with offspring sleep problems (β = 0.014, 95% CI [0.007, 0.038]). Conclusions: Our findings showed the importance of psychological distress and psychological aggression in the intergenerational effect of trauma on offspring sleep problems. Specific interventions aimed at improving mental health and parenting practices should be provided for parents who were exposed to ACEs. [ABSTRACT FROM AUTHOR]

Objective: Unusual clinical course Background: The pediatric population, due to its distinct anatomy and physiology, often presents with unique mechanisms of trauma, leading clinicians to encounter diverse and sometimes unexpected injuries. Whether these injuries result from blunt or penetrating trauma, they may involve intra-abdominal organs in pediatric patients. Additionally, there are occasional occurrences where injuries affect rare sites such as the pylorus in an isolated manner within this age group. Clinicians must be prepared to address a wide range of injury patterns to ensure optimal outcomes for pediatric patients experiencing trauma to intra-abdominal structures such as the pylorus. Case Report: We report a 19-month-old boy who presented with abdominal pain, crying, and repeated vomiting of gastric contents after a wardrobe fell on his upper torso. His vital signs were stable except that he was tachycardiac. Upon investigation, abdominal computed tomography (CT) revealed pneumoperitoneum, free peritoneal fluid, and inflammatory changes in the intestinal wall, suggesting hollow viscus injury. Exploratory laparotomy was performed, and complete transection of the pyloric area of the stomach was identified. The pancreatic and biliary ducts were intact. On postoperative day 5, an upper gastrointestinal (UGI) contrast study prior to initiating oral feeding was done and showed normal findings with no contrast leakage. His postoperative course was unremarkable. Conclusions: Isolated pyloric injuries following blunt trauma are rare with no known case reports in pediatric age group. High morbidity and mortality rates can result from traumatic gastrointestinal injuries including the involvement of pylorus. Therefore, accurate diagnosis and prompt management are essential for an improved outcome. [ABSTRACT FROM AUTHOR]

Exposure to adverse childhood experiences (ACEs) is recognised globally as a risk factor for health problems in later life. Awareness of ACEs and associated trauma is increasing within schools and educational settings, as well as the demand for supportive services to address needs. However, there is a lack of clear evidence for effective interventions which can be delivered by non-clinicians (e.g., the school staff themselves). Thus, we undertook a systematic review to answer the question: What evidence exists for the efficacy of non-clinician delivered trauma-based interventions for improving mental health in school-age youth (4–18 years) who have experienced ACEs? The protocol for the review is registered in the PROSPERO International Prospective Register of Systematic Reviews (ID: CRD42023417286). We conducted a search across five electronic databases for studies published between January 2013 and April 2023 that reported on interventions suitable for non-clinician delivery, were published in English in the last 10 years, and involved participants aged 4–18 years (school-age) that had exposure to ACEs. Of the 4097 studies identified through the search, 326 were retrieved for full text screening, and 25 were included in the final review. Data were extracted from included articles for analysis and selected studies were quality assessed using validated assessment tools. Data were analysed through narrative synthesis. There was considerable heterogeneity in study design, outcome measures, and the interventions being studied. Interventions included CBT, mindfulness and art-based programs. A key finding was that there is a lack of high-quality research evidence to inform non-clinician delivered trauma-informed interventions. Many included studies were weak quality due to convenience sampling of participants and potential bias. Cognitive Behavioural Therapy (CBT)-based approaches are tentatively suggested as a suitable target for future rigorous evaluations of interventions addressing ACE-related trauma recovery and mental health improvement in school-age youth. [ABSTRACT FROM AUTHOR]

Background: Obsessive-compulsive disorder (OCD) and eating disorders (ED) share common features, including the presence of obsessions and compulsions, and they often co-occur. Additionally, there is a significant comorbidity between ED and childhood traumatic experiences (CTE), as well as between CTE and OCD. Various biological and environmental factors have been proposed to explain the connection between ED, OCD, and CTE. This study explores the link between CTE and the comorbidity of ED and OCD, with the hypothesis that specific types of CTE may increase the risk of developing OCD in individuals with ED. Methods: Participants (N = 562) were enrolled at an eating disorder unit in Montpellier, France, between March 2013 and January 2020. The Childhood Trauma Questionnaire (CTQ), Eating Disorder Examination Questionnaire (EDE-Q), and Mini International Neuropsychiatric Interview (MINI) were used to evaluate childhood maltreatment, assess clinical characteristics associated with ED, and categorize participants into two groups: patients with and without OCD. Results: Bivariate analysis revealed that patients with comorbid ED and OCD had higher EDE-Q scores (p < 0.001), more anxiety disorders (p < 0.001), depressive disorders (p = 0.02), post-traumatic stress disorder (PTSD) (p < 0.001), and a higher incidence of sexual abuse (p < 0.001) and physical neglect (p = 0.04) compared to those without OCD. Multivariate analysis showed that the association between CTE and OCD was influenced by the presence of an anxiety disorder (p = 0.01) and a higher EDE-Q total score (p = 0.03), with a significant association with a history of sexual abuse (p = 0.04). Conclusions: This demonstrates that CTE increases the risk of comorbid OCD in ED patients, correlating with more clinically severe ED and a higher likelihood of anxiety disorders. Plain English summary: This study looked at the link between childhood trauma and the occurrence of both obsessive-compulsive disorder (OCD) and eating disorders (ED). We studied 562 participants who were being treated for eating disorders in Montpellier, France, over a seven-year period. We used various questionnaires to evaluate their childhood experiences, eating disorder symptoms, and the presence of OCD. We found that people with comorbid OCD and ED had more severe eating disorder symptoms and higher rates of anxiety, depression, and PTSD compared to those with just an eating disorder. These individuals were also more likely to have experienced sexual abuse and physical neglect during childhood. Our analysis showed that the connection between childhood trauma and OCD in patients with eating disorders was influenced by the presence of anxiety disorders and more severe eating disorder symptoms. Specifically, a history of sexual abuse was a significant factor. In summary, childhood trauma, especially sexual abuse, increases the risk of having both OCD and an eating disorder. This highlights the importance of screening for OCD and addressing past traumas in patients with eating disorders to provide better, more personalized care. [ABSTRACT FROM AUTHOR]

IntroductionMethodResultsDiscussionAdverse childhood experiences (ACEs) play a key role in child development and subsequent adult health. This study aims to create an overview of the music therapy research published on children and youth with ACEs, specifically on available interventions, their effectiveness, associated therapy goals and other music therapy characteristics.A scoping review was conducted on peer-reviewed articles published in medical, psychological and music therapy databases between January 2000 and April 2022. We included articles that discussed the use of music therapy in combination with any ACE and focused on participants aged 24 years or younger.A total of 1,250 articles were identified, of which 35 matched the inclusion criteria. A total of 173 music therapy interventions were found, addressing 20 different ACEs and 83 treatment goals. Only four studies reported significant effects, each on different outcome measures.There is a broad variety in reported music therapy interventions, goals and methods. A clear overview of the interventions used in treating the consequences for specific ACEs was difficult to create as divergent descriptions were used for what essentially might be similar interventions and goals. Music therapists seem to adjust their approach to specific needs of the client, but the ambiguity of reports currently hampers firm conclusions. To reach this goal, it is recommended that music therapists report their interventions, goals and methods in a more standardized way and suggestions to do so are provided. [ABSTRACT FROM AUTHOR]

The 33-item Childhood Trauma Questionnaire (CTQ-33) is a recently developed tool expanded from the 28-item Childhood Trauma Questionnaire (CTQ-28) to assess childhood trauma events, which showed good test-retest reliability over 2 weeks. However, little is known regarding the factor structure and long-term test-retest reliability of the CTQ-33. To fill such a gap, this study investigated the factorial validity of the CTQ-33 and test-retest reliability of the scale over a relatively long interval of 1 year. Data on demographics, the CTQ-33 scores, and mental health statuses such as depressive/anxiety symptoms were collected in Chinese adolescents (n = 188) twice across a one-year period. Results of the confirmatory factor analysis (CFA) revealed that the Chinese version of CTQ-33 has close factor validity when compared to the original CTQ-28 in college students. Furthermore, the total and most subscale scores of the CTQ-33 have fair to good test-retest reliability (intra-class correlation coefficients >0.6 for the total score, and > 0.4 for most subscales), except for the physical abuse subscale. Moreover, we replicated previous findings of significant positive relationships between levels of different childhood trauma subtypes using the CTQ-33. These findings provide initial evidence supporting that the CTQ-33 is overall reliable to assess childhood traumatic events in adolescents over relatively long intervals. [ABSTRACT FROM AUTHOR]

Violence across Latin America is an increasingly important factor influencing migration to the US. A particular form of violence that is experienced by many Latinx migrants is extortion. This research analyzes the extortion experiences of Latinx immigrant adults arriving at the US southern border and the impact these experiences have on mental health. We find that on average, participants paid $804 in extortion during their migration. The most common perpetrators of extortion in our study were police followed by immigration officials throughout Latin America. Pregnant participants were less likely to experience extortion and adults traveling with children were more likely to be extorted. Participants who were extorted for money reported significantly greater severity of post-traumatic stress disorder (PTSD) symptoms compared to those who were not extorted. This research is the first of its kind to analyze extortion experiences among Latinx immigrants to the US, quantifying the prevalence, amounts paid, countries where extortion occurs, and perpetrators of extortion. In addition, extortion experiences are associated with negative effects on the mental health of newly arrived Latinx immigrants to the US. Based upon these findings, we recommend that extortion should be considered a significant stressor in the migrant experience, particularly for those adults traveling with children. [ABSTRACT FROM AUTHOR]

Depersonalization/derealization disorder (DPD) is a prevalent yet inadequately understood clinical condition characterized by a recurrent or persistent sense of unreality. This study aims to provide insight into DPD through descriptive and comparative analyses involving a large group of Chinese participants. The socio-demographic details (age, gender proportion, education, occupational status, marital status), depersonalized and dissociative symptom characteristics (symptomatic factors or subscales of the Cambridge Depersonalization Scale and the Dissociative Experiences Scale), development trajectory (age of onset, potential precipitating factors, course characteristics), treatment history (duration of delayed healthcare attendance, duration of delayed diagnosis, previous diagnoses), and adverse childhood experiences of the DPD patients are presented. Comparisons of anxiety and depressive symptoms, alongside psychosocial functioning, between DPD participants and those diagnosed with generalized anxiety disorder, bipolar disorders, and major depressive disorder were conducted. The analysis highlights a higher male preponderance and early onset of DPD, symptomatology marked by derealization, notable impairment in psychosocial functioning, and prolonged periods of delayed healthcare attendance and diagnosis associated with symptom severity. Furthermore, noteworthy relationships between adverse childhood experiences and symptom levels were identified. The findings substantiate the view that DPD is a serious but neglected mental disorder, urging initiatives to improve the current condition of DPD patients. [ABSTRACT FROM AUTHOR]

Background: Psychological and trauma-related factors are associated with many diseases and mortality. However, a comprehensive assessment of the association between psycho-trauma exposures and aging acceleration is currently lacking. Methods: Using data from 332,359 UK Biobank participants, we calculated biological aging acceleration, indexed by the presence of leukocyte telomere length (LTL) deviation (i.e., the difference between genetically determined and observed LTL > 0). The acceleration of facial aging (i.e., looking older than the chronological age) was assessed using a self-report question. Then, we estimated the associations of each psycho-trauma factor with biological and facial aging acceleration, using logistic regression models adjusted for multiple important covariates. Furthermore, restricted to 99,180 participants with complete psychological and trauma-related data, we identified clusters of individuals with distinct psycho-trauma patterns using the latent class analysis method and assessed their associations with aging acceleration using similar models. Results: We observed most of the studied psycho-trauma factors were associated with biological and facial aging acceleration. Compared to the "Absence of trauma and psychopathology" cluster, the "adverse childhood experiences (ACEs) with psychopathology" cluster showed strong associations with those aging measurements (odds ratio [OR] = 1.13 [1.05 − 1.23] for biological and 1.52 [1.18 − 1.95] for facial aging acceleration), while no such association was observed for the "ACEs without psychopathology" cluster (1.04 [0.99 − 1.09] and 1.02 [0.84 − 1.24]. Conclusions: Our study demonstrated significant associations of psycho-trauma factors with both biological and facial aging acceleration. The differential aging consequences observed among ACEs exposed individuals with and without psychopathology prompt interventions aimed to improve individuals' psychological resilience to prevent aging acceleration. [ABSTRACT FROM AUTHOR]

Introduction Post-traumatic stress disorder (PTSD) is a primary military psychiatric condition with complex etiology including strong genetic and/or environmental influences. Environmental influences and demographics can play a role in supporting underlying genetic traits for clinical utility evaluation as risk modifying factors. We are undertaking an IRB approved study to evaluate polygenic scores of PTSD risk in the adverse childhood experience and serotonin (ACES) transporter cohort. Materials and Methods Baseline demographic characteristics and statistical modeling of 291 active duty service members from ACES cohort were used and excluded individuals with traumatic brain injury-induced loss of consciousness, pre-deployment PTSD or anxiety disorder, and pre-deployment prescription of antidepressants or psychoactive medications. Summary of categorical and numerical variables were evaluated using chi-square and t -test, respectively. We model PTSD risk and associated scores using linear and logistic regressions. Results The ACES subset was 79.1% males, multi-ancestry, and mean age of 38.3 years. Most PTSD individuals received behavioral therapy (89.6%) and/or prescribed antidepressants (67%) had higher scores in ACES, combat exposure scales, PTSD checklist military version, neurobehavioral symptom inventory, Pittsburg sleep quality index, insomnia severity index, and composite autonomic symptom score surveys and were less likely to expect future deployment. A positive correlation between age, total months deployed, ACES, CES, PCL-M, and positive-PTSD diagnosis were consistent but not in older individuals, who were more likely and frequently deployed although increasing risk for combat exposure. Conclusion Demographic characteristics of the ACES cohort fit a coherent model of risk for PTSD to evaluate polygenic scores. Additional research is merited to understand PTSD effects on these confounding factors. [ABSTRACT FROM AUTHOR]

ABSTRACT Borderline personality disorder (BPD) is often perceived as being more common in females, since women are more likely to seek help and be diagnosed. However, epidemiological studies have reported no sex differences in community prevalence. The purpose of this study was to learn from the narrative journeys of men who have received a diagnosis of BPD. Eight men participated, mean age 45.9 years (range 27–73 years). Recruitment was through clinician referrals at the study site and via social media and website advertising. Participants consented to a 60–90‐min semi‐structured interview via an audio‐visual digital platform. Audio recordings were transcribed and analysed using Interpretative Phenomenological Analysis (IPA). Three themes were identified: (i) The Emergence of Symptoms, (ii) Reaching Crisis Point and (iii) Receiving a Diagnosis. Participants reported many adverse experiences during childhood and adolescence. Early symptoms were often exacerbated by emotionally invalidating caregiving. Participants reported seeking mental health support only after reaching a crisis point, which often arose following an employment‐related stressor. Participants typically initiated help‐seeking by consulting a General Practitioner. Long delays were reported from initial help‐seeking to being diagnosed with BPD; all expressed relief upon diagnosis. The findings highlight the deleterious consequences of emotional invalidation in participants' mental health and their capacity to access timely support. General Practitioners play a critical role in identifying probable symptoms of BPD in men and are the gateway to referral to psychiatrists and psychologists. It is vital that education is provided to assist their important work. [ABSTRACT FROM AUTHOR]

This study investigates the association between adverse childhood experiences (ACEs) and job satisfaction in adulthood, mediated by posttraumatic beliefs and core self‐evaluation (CSE). Based on the literature, we hypothesized that posttraumatic beliefs, potentially developed following ACEs, would have negative effects on individuals' CSE and job satisfaction. Structural equation modeling of survey data from 384 employees with at least one ACE revealed that posttraumatic beliefs fully mediated the effect of ACEs on both job satisfaction and CSE. Furthermore, CSE was a partial mediator between posttraumatic beliefs and job satisfaction. These findings highlight the importance of adopting trauma‐informed approaches in employment counseling. [ABSTRACT FROM AUTHOR]