246 results on '"Alexandrov, I. A."'
Search Results
202. On the mechanism of grain subdivision during severe plastic deformation
- Author
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Romanov, A. E., Orlova, T. S., Enikeev, N. A., Ayrat Nazarov, Alexandrov, I. V., and Valiev, R. Z.
203. On the description of misorientation of intergranular boundaries during severe plastic deformation
- Author
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Nariman Enikeev, Alexandrov, I. V., Valiev, R. Z., Orlova, T. S., and Romanov, A. E.
204. The effect of microarc oxidation (MAO) modes on corrosion behavior of high-silicon aluminum alloy
- Author
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Kiselyeva, S. K., Zaynullina, L. I., Marina Abramova, Dudareva, N. Y., and Alexandrov, I. V.
- Subjects
aluminum alloys ,lcsh:TA1-2040 ,lcsh:Technology (General) ,lcsh:T1-995 ,micohardness ,corrosive behavior ,lcsh:Engineering (General). Civil engineering (General) ,microarc oxidation - Abstract
The investigation studies the properties of hardened surface layers, developed with the microarc oxidation method (MAO) on ingots of a Al-Si alloy. It has been proved that properties of the developed surfaces (microhardness, thickness, porosity and corrosion properties) depend on the concentration of electrolyte components.
205. ATLAS: Detector and physics performance technical design report. Volume 1
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Airapetian, A., Grabsky, V., Hakopian, H., Vartapetian, A., Dick, B., Fares, F., Guy, L. P., Moorhead, G. F., Sevior, M. E., Taylor, G. N., Tovey, S. N., Hashemi-Nezhad, R., Peak, L., Saavedra, A., Ulrichs, J., Epp, B., Ghete, V. M., Girtler, P., Kneringer, E., Kuhn, D., Nairz, A., Rudolph, G., Schaller, M., Schweiger, D., Abdinov, O. B., Akhmedov, A., Akhoundov, A., Javadov, N., Khalilzade, F. T., Mekhdiyev, R. R., Oussoubov, Z., Rzayev, H. J., Baturitsky, M. A., Bogush, A. A., Gazizov, A. Z., Gilevsky, V. V., Kulchitsky, Y., Kuzmin, M. V., Levchuk, M. I., Satsunkevich, I. S., Kuzhir, P., Medvedev, V., Pazin, A., Prokoshin, F., Soroko, A., Starovoytov, P., Caloba, L. P., Dos Anjos, A., Gomes, R., Maidantchik, C. L., Marroquim, F., Seixas, J. M., Thome, Z. D., Armstrong, W. W., Burris, W., Davis, R., Gingrich, D. M., Hewlett, J. C., Holm, L., Macpherson, A. L., Mullin, S., Pinfold, J. L., Schaapman, J., Soukup, J., Wampler, L., Axen, D., Armitage, J., Dixit, M., Estabrooks, P., Losty, M., Neuheimer, E., O Neil, M., Oakham, G., Azuelos, G., Leroy, C., Marullo, F., Mazini, R., Roy, P., Bailey, D. C., Bhadra, S., Martin, J. F., Mayer, J. K., Orr, R. S., Sinervo, P. K., Stairs, G. G., Trischuk, W., Astbury, A., Birney, P., Hodges, T., Langstaff, R., Oram, C., Dobbs, M., Fincke-Keeler, M., Fortin, D., Keeler, R., Lefebvre, M., O Neil, D., Poffenberger, P., Roney, M., Sobie, R., Aleksa, M., Ambrosini, G., Anderssen, E., Anghinolfi, F., Arnaud, C., Bachy, G., Barberio, E., Benincasa, G., Bergsma, F., Bertinelli, F., Bjorset, L., Bloess, D., Bock, R., Bogaerts, J., Boosten, M., Bremer, J., Burckhart, D., Burckhart, H. J., Butin, F., Cataneo, F., Chesi, E., Chevalley, J. L., Cobal, M., Danielsson, H., Dauvergne, J. P., Acqua, A., Dittus, F., Dobinson, R., Dobson, M., Drevermann, H., Dudarev, A., Dydak, F., Ellis, N., Fabjan, C. W., Farthouat, P., Fassnacht, P., Fernandez, A., Flegel, W., Francis, D., Froidevaux, D., Giancomini, F., Gianotti, F., Gildemeister, O., Gschwendtner, E. M., Hallgren, B., Hansen, J., Hatch, M., Haug, F., Hauser, R., Hauviller, C., Havet, C., Heeley, R., Henriques, A., Hervas, L., Hoffmann, H. F., Hogbe-Nlend, F., Hoimyr, N., Jarp, S., Jarron, P., Jenni, P., Jones, R., Kantardjian, G., Kaplon, J., Klioutchnikova, T., Knobloch, J., Kulseth, M., Lacasta, C., Lasseur, C., Lehraus, I., Lemeilleur, F., Lichard, P., Linde, F., Lopez, J., Lozano, J., Mandl, M., Mapelli, L., Martin, B., Maugain, J. -M, Mclaren, R. A., Meier, D., Meinhard, H., Mitsou, V., Mornacchi, G., Myers, D., Nessi, M., Nicquevert, B., Niinikoski, T., Onions, C., Pailler, P., Passardi, G., Petersen, J., Placci, A., Poppleton, A., Posch, C., Poulard, G., Price, M., Riedler, P., Roe, S., Rohrbach, F., Rudge, A., Schmid, P., Schuler, G., Schwick, C., Shears, T., Simion, S., Soulhat, J., Spiwoks, R., Stavrianakou, M., Stavropoulos, G., Szeless, B., Tapprogge, S., Tartarelli, G. F., Ten Kate, H., Teterin, V., Tischhauser, H., Treichel, M., Tremblet, L., Tuura, L., Turala, M., Unel, G., Bij, H., Vincke, H., Boehn-Bucholz, R., Voss, R., Vreeswijk, M., Vuillemin, V., Weilhammer, P., Werner, P., Witzeling, W., Wotschack, J., Chen, C., Chen, T-Y, Cheng, S., Feng, C., Fu, Y., Kong, F., Li, H., Liu, T., Lu, W. D., Ma, J. M., Meng, X., Ouyang, Q., Qi, M., Tong, G. L., Wang, C., Xie, Y. G., Xue, L., Xu, G. F., Yang, B., Yang, T., Ye, B., Yu, X. Q., Zhang, B., Zhang, N., Zhang, Q. J., Zhao, J., Jinan, Bohm, J., Hakl, F., Hrivnac, J., Jirina, M., Lednicky, R., Lokajicek, M., Mares, J. J., Nemecek, S., Rizek, S., Sicho, P., Simak, V., Stastny, J., Stedron, M., Vanickova, M., Vrba, V., Weichert, J., Zitek, K., Davidek, T., Dolejsi, J., Dolezal, Z., Kucera, M., Leitner, R., Soustruznik, K., Suk, M., Tas, P., Trka, Z., Valkar, S., Wilhelm, I., Zdrazil, M., Jakubek, J., Kubasta, J., Ota, J., Pospisil, S., Sinor, M., Sodomka, J., Sopko, B., Stekl, I., Tomiak, Z., Dam, M., Hansen, J. D., Hansen, J. R., Hansen, P., Aubert, B., Beaugiraud, B., Billat, C., Boniface, J., Cailles, M., Chollet-Leflour, F., Colas, J., Duchesneau, A., Dumont-Dayot, N., Girard, C., Gouanere, M., Jezequel, S., Kambara, H., Lafaye, R., Lesueur, J., Masserot, A., Massol, N., Moynot, M., Perrodo, P., Perrot, G., Prast, J., Riccadonna, X., Sauvage, G., Thion, J., Wingerter-Seez, I., Zitoun, R., Zolnierowski, Y., Biscarat, C., Chadelas, R., Crouau, M., Daudon, F., Grenier, P., Guicheney, Ch, Hebrard, C., Lefevre, R., Montarou, G., Pallin, D., Podlyski, F., Reinmuth, G., Santoni, C., Says, L. P., Vazeille, F., Andrieux, M. L., Collot, J., Dzahini, D., Ferrari, A., Hostachy, J. Y., Martin, Ph, Pouxe, J., Rabier, C., Rey-Campagnolle, M., Saintignon, P., Stassi, P., Bee, C., Blanquart, L., Breugnon, P., Calvet, D., Clemens, J-C, Delpierre, P., Dinkespiler, B., Djama, F., Duval, P-Y, Etienne, F., Fede, E., Hallewell, G., Henry-Couannier, F., Hinz, L., Karst, P., Laugier, D., Le Suu, A., Martin, L., Martin, O., Meessen, C., Mirea, A., Monnier, E., Mouthuy, T., Nacasch, R., Nagy, E., Negroni, S., Nicod, D., Olivier, C., Pralavorio, P., Quian, Z., Repetti, B., Rondot, C., Rousseau, D., Rozanov, A., Sauvage, D., Tisserant, S., Touchard, F., Vacavant, L., Valin, I., Vigeolas, E., Wielers, M., Arnault, C., Auge, E., Barrand, G., Belot, G., Beney, J. L., Blaquiere, M., Bonivento, W., Bourdarios, C., Breton, D., Chollet, C., Coulon, J-P, Cros, Ph, La Taille, C., Delebecque, P., Falleau, I., Fallou, A., Fournier, D., Grivaz, J-F, Imbert, P., Jacquier, Y., Mace, G., Martin-Chassard, G., Mencik, M., Merkel, B., Noppe, J-M, Parrour, G., Perus, A., Petroff, P., Puzo, P., Richer, J-P, Schaffer, A-C, Seguin-Moreau, N., Serin, L., Tocut, V., Vales, F., Veillet, J-J, Vernay, E., Zerwas, D., Astesan, F., Bertoli, W., Canton, B., David, J., Fichet, S., Fleuret, F., Imbault, D., Lacour, D., Laforge, B., Le Dortz, O., Martin, D., Poggioli, L., Rossel, F., Schwemling, P., Amadon, A., Bauer, F., Belorgey, J., Berriaud, C., Berthier, R., Borgeaud, P., Bystricky, J., Cacaut, D., Chalifour, M., Chevalier, L., Cloue, O., Dael, A., Delagnes, E., Desages, F., Durand, D., Ernwein, J., Gachelin, O., Gallet, B., Gastineau, B., Girolamo, P., Guyot, C., Hansl-Kozanecka, T., Hubbard, J. R., Huet, M., Joudon, A., Juster, F. P., Kiourkos, S., Kozanecki, W., Laporte, J. F., Le Coreller, A., Le Du, P., Lesmond, C., Lugiez, F., Machefert, F., Mandjavidze, I., Mansoulie, B., Mayri, C., Molinie, F., Mur, M., Pabot, Y., Pascual, J., Perrin, P., Ponsot, P., Rey, J. M., Rouger, M., Schuller, J. P., Schune, Ph, Schwindling, J., Sun, Z., Taguet, J. P., Teiger, J., Thooris, B., Tirler, R., Hille, H., Virchaux, M., Chikovani, L., Chiladze, B., Djobava, T., Gabunia, L., Gogiberidze, G., Grigalashvili, T., Khelashvili, A., Khorguashvili, Z., Khubua, J., Kipiani, K., Koshtoev, V., Liparteliani, A., Metreveli, Z., Mosidze, M., Salukvadze, R., Sopromadze, D., Topchishvili, L., Ackers, M., Andre, F., Andreazza, A., Comes, G., Fischer, P., Geich-Gimbel, C., Klasen, V., Keil, M., Kobel, M., Kuhl, T., Meuser, S., Ockenfels, W., Stockmanns, T., Treis, J., Wermes, N., Geiser, A., Goessling, C., Huegging, F., Wuestenfeld, J., Wunstorf, R., Baer, Th, Chen, J., Ebling, D. G., Herten, G., Irsigler, R., Kollefrath, M., Landgraf, U., Lauxtermann, S., Ludwig, J., Mohr, W., Paschhoff, V., Rehmann, V., Rolker, B., Runge, K., Schaefer, F., Scherberger, G., Schmid, T., Webel, M., Weber, C., Geweniger, C., Hanke, P., Kluge, E. -E, Mahboubi, K., Meier, K., Pfeiffer, U., Putzer, A., Schumacher, C., Tittel, K., Wunsch, M., Fuchs, K., Geib, K. H., Jakobs, K., Kleinknecht, K., Koepke, L., Marschalkowski, E., Merle, K., Othegraven, R., Quast, G., Renk, B., Schaefer, U., Walkowiak, W., Zeitnitz, C., Kornmesser, K., Kugel, A., Lay, R., Ludvig, J., Maenner, R., Noffz, K-H, Ruehl, S., Sessler, M., Simmler, H., Singpiel, H., Chouridou, S., Deile, M., Kortner, O., Hessey, N. P., Schaile, D., Staude, A., Strohmer, R., Trefzger, T., Ackermann, K., Aderholz, M., Andricek, L., Blum, W., Bratzler, U., Brettel, H., Dietl, H., Dulny, B., Fent, J., Gruhn, C., Hauff, D., Koffeman, E., Kroha, H., Lutz, G., Manz, A., Moser, H. -G, Oberlack, H., Ostapchuk, A., Richter, R., Richter, R. H., Schacht, P., Schael, S., Soergel, V., Stenzel, H., Striegel, D., Tribanek, W., Holder, M., Schoefer, B., Ziolkowski, M., Becks, K. H., Braun, H., Drees, J., Gerlach, P., Glitza, K. W., Gregor, I. M., Hamacher, K., Kersten, S., Lenzen, G., Linder, C., Thadome, J., Wahlen, H., Dris, M., Filippas, A., Fokitis, E., Gazis, E. N., Katsoufis, E., Maltezos, S., Papadopoulou, T., fasssouliotis, D., Giokaris, N., Ioannou, P., Kourkoumelis, C., Pancheluga, V., Petridis, A., Tatsis, S., Tzanakos, G. S., Vassiliou, M., Bouzakis, C., Chardalas, M., Dedoussis, S., Efstathiou, K., Lagouri, Th, Liolios, A., Paschalias, P., Petridou, C., Sampsonidis, D., Vichou, I., Zamani, M., Dado, S., Harel, A., Landesman, H., Lupu, N., Robins, S., Rozen, Y., Tarem, S., Abramowicz, H., Alexander, G., Bella, G., Benary, O., Dagan, S., Etzion, E., Grunhaus, J., Oren, Y., Breskin, A., Chechik, R., Duchovni, E., Eisenberg, Y., Gross, E., Hass, M., Karshon, U., Lellouch, D., Levinson, L., Mikenberg, G., Ayad, R., Capua, M., Lagatta, A., La Rotonda, L., Schioppa, M., Susinno, G., Valdata-Nappi, M., Bilokon, H., Cerutti, F., Chiarella, V., Curatolo, M., Dulach, B., Esposito, B., Ferrer, M. L., Maccarrone, G., Moccia, S., Pace, E., Pepe-Altarelli, M., Spitalieri, M., Zuffranieri, F., Barberis, D., Beccherle, R., Caso, C., Dameri, M., Darbo, G., Gagliardi, G., Gemme, C., Morettini, P., Musico, P., Olcese, M., Osculati, B., Parodi, F., Pozzo, A., Ridolfi, G., Rossi, L., Sette, G., Creti, P., Gorini, E., Grancagnolo, F., Palamara, O., Petrera, S., Primavera, M., Acerbi, E., Aleppo, M., Alessandria, F., Battistoni, G., Broggi, F., Caccia, M., Camin, D., Cavalli, D., Costa, G., Fanti, M., Labanca, N., Lari, T., Mandelli, L., Mazzanti, M., Meroni, C., Perini, L., Ragusa, F., Resconi, S., Sala, P., Troncon, C., Vanini, S., Vegni, G., Volpini, G., Aloisio, A., Alviggi, M. G., Cevenini, F., Chiefari, G., Asmundis, R., Merola, L., Napolitano, M., Patricelli, S., Cambiaghi, M., Conta, C., Ferrari, R., Fraternali, M., Lanza, A., Livan, M., Negri, A., Polesello, G., Rimoldi, A., Vercesi, V., Cavasinni, V., Cologna, S., Costanzo, D., Del Prete, T., Di Girolamo, B., Flaminio, V., Lami, S., Marrocchesi, P. S., Mazzoni, E., Paoletti, R., Renzoni, G., Roda, C., Spano, F., Suglia, R., Usai, G., Bagnaia, P., Bini, C., Caloi, R., Cardini, A., Cavallari, A., Ciapetti, G., Zorzi, G., Dimattia, A., Falciano, S., Gauzzi, P., Gentile, S., Lacava, F., Luci, C., Luminari, L., Marzano, F., Mirabelli, G., Nisati, A., Petrolo, E., Pontecorvo, L., Veneziano, S., Zanello, L., Aielli, G., Baranov, S., Camarri, P., Cardarelli, R., Di Ciaccio, A., Liberti, B., Paoloni, A., Santonico, R., Bacci, C., Baroncelli, A., Ceradini, F., Farilla, A., Iodice, M., Orestano, D., Pastore, F., Spiriti, E., Stanescu, C., Cauz, D., D Auria, S., Angelis, A., Pauletta, G., Santi, L., Scuri, B., Waldner, F., Del Papa, C., Tanaka, S., Asai, M., Iwata, Y., Ohsugi, T., Amako, K., Arai, Y., Fujii, H., Haruyama, T., Ikeno, M., Iwasaki, H., Kanzaki, J., Kohriki, T., Kondo, T., Manabe, A., Morita, Y., Nomachi, M., Ohska, T. K., Sasaki, O., Sasaki, T., Terada, S., Unno, Y., Watase, Y., Yamamoto, A., Yasu, Y., Kawagoe, K., Kurashige, H., Nozaki, M., Takeda, H., Sakamoto, H., Sasao, N., Takashima, R., Nagasaka, Y., Tanaka, Y., Nagamatsu, M., Yoshida, H., Takeshita, T., Hasegawa, Y., Homma, K., Imori, M., Kawamoto, T., Kobayashi, T., Fukunaga, C., Hamatsu, R., Emura, T., Chakir, H., Cherkaoui, R., Goujdami, D., El Kacimi, M., Hoummada, A., Saidi, H., Sayouty, E., Bobbink, G. J., Bos, K., Boterenbrood, H., Buis, E. J., Dankers, R. J., Daum, C., Groenstege, H., Hartjes, F., Hendriks, P., Heubers, W., Kaan, B., Kieft, G. N. M., Kluit, P., Kluit, R., Massaro, G. G. G., Meddeler, G., Peeters, S., Reichold, A., Rewiersma, P. A. M., Schuijlenburg, H., Spelt, J., Vermeulen, J. C., Werneke, P., Woudstra, M., Eijk, B., Graaf, H., Brouwer, C., Crijns, F. J. G. H., Dijkema, J. A., Jong, S. J., Kittel, W., Klok, P. F., Lavrijsen, W. T. L. P., Koenig, A. C., Metzger, W. J., Pols, G. -J, Schotanus, D. J., Wijnen, Th A. M., Eigen, G., Frodesen, A. G., Klovning, A., Stugu, B., Bugge, L., Buran, T., Dorholt, O., Kristiansen, H., Madsen, R. A., Marshal, A., Midttun, G., Read, A. L., Rohne, O. M., Stapnes, S., Strandlie, A., Sundal, B., Blocki, J., Bocian, D., Gadomski, S., Gornicki, E., Godlewski, J., Hajduk, Z., Iwanski, W., Kaczmarska, A., Kisielewski, B., Korcyl, K., Madeyski, B., Malecki, P., Moszczynski, A., Olszowska, J., Piotrzkowski, K., Richter-Was, E., Sapinski, M., Wolter, M., Dabrowski, W., Grybos, P., Idzik, M., Jagielski, S., Jelen, K., Kiesilewska, D., Koperny, S., Kowalski, T., Rulikowska-Zarebska, E., Amaral, P., Amorim, A., Carvalho, J., Casarejos, E., David, M., Gomes, A., Gomes, J., Ivaniouchenkov, I., Maio, A., Maneira, M., Martins, J. P., Onofre, A., Pinhao, J., Santos, J., Silva, J., Varanda, M., Wolters, H., Alexa, C., Arsenescu, R., Badescu, E., Boldea, V., Caprini, I., Caprini, M., Constantin, F., Constantinescu, S., Dita, P., Dita, S., Micu, A., Micu, L., Niculescu, M., Pantea, D., Radu, A., Artamonov, A., Epchtein, V., Gorbunov, P., Gurin, R., Jemanov, V., Khovansky, V., Koutchenkov, A., Kruchinin, S., Maslennikov, A., Ryabinin, M., Shatalov, P., Tsoukerman, I., Zaitsev, V., Zeldovich, S., Akimov, A., Belov, M., Blagov, M., Fedorchuk, R., Gavrilenko, I., Kaioumov, F., Komar, A., Konovalov, S., Kopytine, M., Mouraviev, S., Popov, L., Shikanyan, A., Shmeleva, A., Snesarev, A., Speransky, M., Sulin, V., Tikhomirov, V., Vassilieva, L., Yakimenko, M., Bondarenko, V., Dolgoshein, B., Konstantinov, A., Romaniouk, A., Semenov, S., Smirnov, S., Sosnovtzev, V., Bashindjagian, G. L., Basiladze, S. G., Berejnoi, A., Erasov, A. B., Grishkevich, Y., Karmanov, D. E., Kramarenko, V. A., Larichev, A. N., Melikhov, D. I., Merkin, M. M., Nikitin, N. V., Rizatdinova, F. K., Selikov, A. V., Sivoklokov, S. Yu, Smirnova, L. N., Zverev, E. G., Batrakov, A., Chekhtman, A., Fedotov, M., Gaponenko, I., Klimenko, S., Kollegov, M., Kozlov, V., Kuper, E., Merzlyakov, Y., Panin, V., Shamov, A., Telnov, V., Tikhonov, Y., Velikzhanin, Y., Amelin, D. V., Ammosov, V. V., Antipov, Yu M., Batarin, V., Bogoliubsky, M. Yu, Borissov, A. A., Borissov, E., Bozko, N. I., Bryzgalov, V. V., Chekulaev, S. V., Denisov, S. P., Dushkin, A. Yu, Fakhroutdinov, R., Fenyuk, A. B., Gapienko, V. A., Gilitsky, Yu V., Goryatchev, V., Gouz, Yu P., Karyukhin, A. N., Khokhlov, Yu A., Kirsanov, M. M., Kiryunin, A. E., Klyukhin, V., Kojine, A., Kononov, A. I., Konstantinov, V., Kopikov, S. V., Korotkov, V. A., Kostrikov, M. E., Kostyukhin, V. V., Kravtsov, V. I., Kulemzin, A., Kurchaninov, L. L., Lapin, V. V., Levitsky, M. L., Los, S., Maximov, V., Miagkov, A. G., Mikhailin, V. N., Minaenko, A. A., Moiseev, A. M., Onuchin, V. A., Pleskach, A. V., Salomatin, Yu I., Senko, V. A., Shein, I., Soldatov, A. P., Solodkov, A. A., Solovianov, O. V., Starchenko, E. A., Sviridov, Yu, Sytnik, V. V., Tchmil, V., Tchountonov, A., Tikhonov, V. V., Tsyupa, Yu, Usenko, E., Vorobiev, A. P., Vovenko, A. S., Zaets, V. G., Zaitsev, A. M., Zimin, S., Zmouchhko, V., Fedin, O., Filimonov, V., Gavrilov, G., Ivochkin, V., Khomoutnikov, V., Kolos, S., Krivchitch, A., Lochak, I., Maleev, V., Nadtochy, A., Patritchev, S., Prokofiev, D., Riabov, J., Schegelsky, V., Soloviev, I., Spiridenkov, E., Zalite, A., Alexandrov, I., Alexeev, G., Alikov, B., Anosov, V., Astvatsaturov, A., Azhgirei, L., Backovic, S., Boyko, I., Budagov, J., Chelkov, G., Cheplakov, A., Chirikov-Zorin, I., Chlachidze, G., Dedovich, D., Dodonov, V., Evtukhovich, P., Fedorov, A., Feshenko, A., Flyagin, V., Glagolev, V., Golikov, V., Golubykh, S., Gongadze, A., Gornushkin, Y., Gostkin, M., Iamburenko, V., Ignatenko, M., Juravlev, N., Kakurin, S., Kallinikov, V., Kalinichenko, V., Kazarinov, M., Kazymov, A., Kekelidze, G., Khasanov, A., Khomenko, B., Khovansky, N., Kotov, S., Kotov, V., Kovtun, V., Krumstein, Z., Kukhtin, V., Kuznetsov, O., Ladygin, E. U., Lazarev, A., Lebedev, A., Ljablin, M., Lomakin, Y., Malyshev, V., Malyukov, S., Manjavidze, D., Merekov, Y., Minashvili, I., Nikolenko, M., Nozdrin, A., Olshevski, A., Peshekhonov, V., Pisarev, I., Podkladkin, S., Pose, R., Potrap, I., Pukhov, O., Romanov, V., Rumyantsev, V., Russakovich, N., Ryabchenko, K., Salihagic, D., Savin, I., Scheltckov, A., Sedykh, Y., Semenov, A., Senchishin, V., Shabalin, D., Shalyugin, A., Shigaev, V., Shilov, S., Simic, M., Sissakian, A., Snyatkov, V., Sorokina, J., Tchepournov, V., Tkachev, L., Tokmenin, V., Topilin, N., Tskhadadze, E., Usov, Y., Vertogradov, L., Vinogradov, V., Vorozhtsov, S., Yarygin, G., Zhuravlev, V., Ban, J., Bruncko, D., Chochula, P., Chytracek, R., Dubnicka, S., Dubnickova, A., Ferencei, J., Garabik, R., Holik, P., Jusko, A., Kladiva, E., Kocper, B., Kubinec, P., Kurca, T., Luptak, M., Masarik, J., Povinec, P., Rosinsky, P., Stanicek, J., Stavina, P., Strizenec, P., Sykora, I., Tokar, S., Vanko, J., Cindro, V., Filipcic, A., Kramberger, G., Mandic, I., Mikuz, M., Tadel, M., Zontar, D., Blanch, O., Blanchot, G., Bosman, M., Cavalli-Sforza, M., Crespo, J. M., Dosil, M., Fernandez, E., Flix, J., Korolkov, I., Martinez, M., Miralles, Ll, Ostankov, A., Pacheco, A., Pena, J. C., Zamora, Y., Barreiro, F., Del Peso, J., Labarga, L., Ballester, F., Bernabeu, J., Camarena, F., Campabadal, F., Carrasco, R., Castillo, M. V., Costa, M. J., Ferrer, A., Fuster, J., Garcia, C., Gonzalez, V., Gonzalez La Hoz, S., Higon, H., Lopez, J. M., Martinez, C., Modesto, P., Moreno, A., Lozano, M., Roldan, J., Romance, J. B., Ros, E., Salt, J., Javier Sanchez, Sanchis, E., Santander, J., Ullan, M., Akesson, T., Almehed, S., Carling, H., Danielson, H., Eerola, P., Egede Anderson, U., Hedberg, V., Jarlskog, G., Korsmo, H., Lorstad, B., Lundberg, B., Mjornmark, U., Akerman, D., Carlson, P., Clement, C., Leven, S., Lund-Jensen, B., Pearce, M., Soderqvist, J., Vanyashin, A., Berglund, S., Bohm, C., Engstrom, M., Hellman, S., Holmgren, S-O, Johansson, E., Jon-And, K., Klereborn, J., Sellden, B., Silverstein, S., Sjolin, J., Yamdagni, N., Bingefors, N., Botner, O., Brenner, R., Bystrom, O., Coadou, Y., Damet, J., Ekelof, T., Gustafsson, L., Hallgren, A., Kullander, S., Staaf, P., Beck, H. P., Borer, K., Hess, M., Lehmann, G., Mommsen, R., Pretzl, K., Bonino, R., Clark, A. G., Couyoumtzelis, C., Demierre, Ph, Efthymiopoulos, I., Kowalewski, R., La Marra, D., Leger, A., Perrin, E., Vuandel, B., Wu, X., Atag, A., Cakir, O., Meric, N., Sultansoy, S., Turk, I., Ulvi Yilmazer, A., Arik, E., Celik, O., Cetin, S. A., Conka, T., Hacinliyan, A., Kurtulus, O., Mailov, A., Nurdan, K., Tanoren, B., Bright-Thomas, P., Charlton, D. G., Dowell, J. D., Garvey, J., Hillier, S. J., Homer, R. J., Jovanovic, P., Kenyon, I. R., Mcmahon, T. J., O Neale, S. W., Staley, R. J., Watkins, P. M., Watson, A. T., Watson, N. K., Wilson, J. A., Batley, J. R., Carter, J. R., Drage, L., Goodrick, M. J., Hill, J. C., Munday, D. J., Parker, M. A., Robinson, D., Wyllie, K. H., Boyle, O., Candlin, D. J., Candlin, E. R. S., Knowles, I. G., Doyle, A. T., Flavell, A. J., Lynch, J. G., Martin, D. J., O Shea, V., Raine, C., Saxon, D. H., Skillicorn, I. O., Smith, K. M., Brodbeck, T. J., Chilingarov, A., Henderson, R. C. W., Hughes, G., Jones, R. W. L., Ratoff, P. N., Sloan, T., Smizanska, M., Allport, P. P., Booth, P. S. L., Carroll, L. J., Cooke, P. A., Greenall, A., Houlden, M. A., Jackson, J. N., Jones, T. J., King, B. T., Maxfield, S. J., Moreton, A., Smith, N. A., Sutcliffe, P., Turner, P. R., Wells, D., Beck, G. A., Carter, A. A., Eisenhandler, E. F., Hughes, D. M., Kyberd, P., Landon, M., Lloyd, S. L., Newman-Coburn, D., Pentney, J. M., Pritchard, T. W., Thompson, G., Blair, G. A., George, S., Green, B. J., Medcalf, T., Strong, J. A., Anderson, B., Attree, D., Butterworth, J., Charalambous, A., Clarke, P., Cranfield, R., Crone, G., Fraser, J., Hayes, D., Hoare, T., Jones, T., Lane, J., Postranecky, M., Sherwood, P., Wheeler, S., Duerdoth, I. P., Dunne, P. W., Foster, J. M., Freestone, J., Hughes-Jones, R. E., Ibbotson, M., Kerr, A., Kolya, S. D., Loebinger, F. K., Marshall, R., Mercer, D., Pater, J., Snow, S., Thompson, R. J., Buira-Clarke, D., Cashmore, R., Coe, P., Hawes, B. M., Hill, J., Holmes, A., Howell, D., Huffman, B. T., Kundu, N., Loken, J. G., Mitra, A., Nickerson, R. B., Reichold, A. R., Renton, P. B., Segar, A. M., Wastie, R. L., Weidberg, A. R., Apsimon, R. J., Baines, J. T., Baynham, D. E., Botterill, D. R., Clifft, R. W., Edwards, M., English, R. L., Fisher, S. M., Gee, C. N. P., Gibson, M. D., Gillman, A. R., Greenfield, D., Hart, J. C., Hatley, R. W., Haywood, S. J., Hill, D. L., Mccubbin, N. A., Middleton, R. P., Morrissey, M. C., Murray, W. J., Nichols, A., Norton, P. R., Payne, B. T., Perera, V. J. O., Phillips, P. W., Pilling, A., Saunders, B. J., Shah, T. P., Tappern, G. J., Tyndel, M., White, D. J., Wickens, F. J., Booth, C. N., Buttar, C. M., Combley, F. H., Dawson, I., Grigson, C., Lehto, M. H., Alam, S., Athar, B., Mahmood, A., Timm, S., Wappler, F., Zhichao, L., Berger, E. L., Blair, R., Dawson, J., Drake, G., Guarino, V., Hill, N., May, E. N., Nodulman, L. J., Price, L. E., Proudfoot, J., Schlereth, J. L., Stanek, R., Wagner, R. G., Wicklund, A. B., Yoshida, R., Cheu, E., Embry, T., Johns, K., Loch, P., Rutherfoord, J., Savine, A., Shaver, L., Shupe, M., Steinberg, J., Tompkins, D., De, K., Gallas, E., Li, J., Sosebee, M., Stephens, R., White, A., Barnett, M., Bintinger, D., Ciocio, A., Einsweiler, K., Gilchriese, M., Haber, C., Hinchliffe, I., Joshi, A., Loken, S., Marchesini, R., Milgrome, O., Niggli, H., Palaio, N., Richardson, J., Shapiro, M., Siegrist, J., Spieler, H., Trilling, G., Ahlen, S., Hazen, E., Shank, J., Simmons, E., Whitaker, J. S., Zhou, B., Behrends, S., Bensinger, J. R., Blocker, C., Hashemi, K., Kirsh, L. E., Wellenstein, H., Alforque, S., Barratt, R., Citterio, M., Gordeev, A., Gordon, H., Graf, N., Gratchev, V., Kandasamy, A., Koehler, J., Kotcher, J., Lissauer, D., Ma, H., Makowiecki, D., Murtagh, M. J., Norton, S., O Connor, P., Paige, F., Polychronakos, V., Protopopescu, S., Radeka, V., Rahm, D. C., Rajagopalan, S., Rescia, S., Smith, G., Sondericker, J., Stephani, D., Stumer, I., Takai, H., Tcherniatine, V., Yu, B., Anderson, K., Bellerive, A., Blucher, E., Glenzinsky, D., Merritt, F., Oreglia, M., Pilcher, J., Pod, E., Sanders, H., Shochet, M., Tang, F., Teuscher, R., Wu, H., Cartiglia, N., Cunitz, H., Dodd, J., Gara, J., Leltchouk, M., Parsons, J., Seman, M., Shaevitz, M., Sippach, W., Willis, W., Zhang, L., Ebenstein, W. L., Goshaw, A. T., Lee, A. M., Oh, S. H., Robertson, W. J., Wang, C. H., Assamagan, K. A., Baker, O. K., Mcfarlane, W. K., Brandenburg, G., Feldman, G. J., Felt, N., Franklin, M. E. B., Huth, J., Oliver, J., Riegler, W., Callahan, J., Hanson, G., Luehring, F., Ogren, H., Rust, D. R., Fahlund, T., Hackett, C., Hall, R., Lankford, A. J., Pier, S., Schernau, M., Stoker, D., Haridas, P., Osborne, L. S., Paradiso, J. A., Pless, I. A., Taylor, F. E., Wadsworth, B. F., Ball, R., Campbell, M., Chapman, J. W., Diehl, E., Goldfarb, S., Hou, S., Kouba, D., Levin, D., Mckee, S., Neal, H. A., Qian, J., Schick, H., Tarle, G., Thun, R., Weaverdyck, C., Abolins, M., Brock, R., Bromberg, C., Ermoline, Y., Huston, J., Linnemann, J., Miller, R., Pineiro, B., Pope, B. G., Richards, R., Weerts, H., Gold, M., Gorfine, G., Hoeferkamp, M., Seidel, S., Fortner, M., Sirotenko, V. I., Willis, S. E., Gan, K. K., Honscheid, K., Kagan, H., Kass, R., Boyd, R., Gutierrez, P., Mcmahon, T., Severini, H., Skubic, P., Snow, J., Strauss, M., Dressnandt, N., Keener, P., Newcomer, F. M., Berg, R., Williams, H. H., Cleland, W. E., Mcdonald, J. E., Paolone, V., Rabel, J., Zuk, G., England, D., Haelen, T., Slattery, P., Dorfan, D., Dubbs, T., Grillo, A., Heusch, C., Kashigin, S., Litke, A., Sadrozinski, H., Seiden, A., Spencer, E., Webster, A., Chou, T. -M, Evans, G., Stroynowski, R., Ye, J., Engelmann, R., Grannis, P., Hobbs, J., Jung, C. K., Mccarthy, B., Rijssenbeek, M., Schamberger, D., Yanagisawa, C., Mann, A., Milburn, R., Napier, A., Sliwa, K., Errede, D., Errede, S., Haney, M. J., Thaler, J., Burnett, T. H., Cook, V., Daly, C., Davisson, R., Forbush, D., Guldenmann, H., Lubatti, H. J., Mockett, P. M., Rothberg, J., Zhao, T., Fasching, D., Gonzalez, S., Jared, R. C., Pan, Y. B., Scott, I. J., Wu, S. L., Yamartino, J. M., and Zobernig, G.
206. Experience with CORBA communication middleware in the ATLAS DAQ
- Author
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Kolos, S., Burckhart-Chromek, D., Flammer, J., Dobson, M., Jones, R., Liko, D., Mapelli, L., Alexandrov, I., Kotov, V., Korobov, S., Mineev, M., Antonio Amorim, Fiuza Barros, N., Klose, D., Pedro, L., Badescu, E., Caprini, M., Kazarov, A., Ryabov, Y., and Soloviev, I.
- Subjects
Detectors and Experimental Techniques - Abstract
As modern High Energy Physics (HEP) experiments require more distributed computing power to fulfill their demands, the need of an efficient distributed online services for control, configuration and monitoring in such experiments becomes increasingly important. This paper describes experience of using standard Common Object Request Broker Architecture (CORBA) middleware for providing a high performance and scalable software, which will be used for the online control, configuration and monitoring in the ATLAS Data Acquisition (DAQ) system. It also recites the experience, which was gained from using several CORBA implementations together and replacing one CORBA broker with another. Finally the paper presents the results of the large scale tests, demonstrating the performance and scalability of the ATLAS DAQ online services. These results show that the standard CORBA is truly appropriate for the highly efficient online distributed computing in the HEP experiments area.
207. Status of the geometry database for the CBM experiment
- Author
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Akishina, E. P., Alexandrov, E. I., Alexandrov, I. N., Irina Filozova, Friese, V., and Ivanov, V. V.
208. Cytogenetical analysis of the chorionic villus samples in prenatal diagnosis of inherited diseases
- Author
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Baranov, V. S., Popova, M. V., Novikova, L. N., Elgart Ya, I., Kharchenko, T. V., Mikhailova, E. P., Gorbunova, V. N., Pigina, T. V., Tsuladze, L. K., Yuri Yurov, and Alexandrov, I. A.
209. The configurations database challenge in the ATLAS DAQ system
- Author
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Soloviev, I., Burckhart-Chromek, D., Dobson, M., Flammer, J., Liko, D., Jones, R., Mapelli, L., Amorim, A., Fiuza Barros, N., Alexandrov, I., Klose, D., Pedro, L., Kotov, V., Mineev, M., Korobov, S., Badescu, E., Mihai Caprini, Kazarov, A., Ryabov, Y., and Kolos, S.
210. Towards enhancement of properties of UFG metals and alloys by grain boundary engineering using SPD processing
- Author
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Valiev, R. Z., Alexandrov, I. V., Enikeev, N. A., Maxim Murashkin, and Semenova, I. P.
211. Simplified three-body problem in nuclear matter
- Author
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Moszkowski, S. A., primary and Alexandrov, I., additional
- Published
- 1979
- Full Text
- View/download PDF
212. Quality and frequency patterns of γ- and neutron-induced visible mutations in Drosophila spermatozoa
- Author
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Alexandrov, I, primary
- Published
- 1984
- Full Text
- View/download PDF
213. Effects of corynebacterium parvum after intraperitoneal injection in hamsters
- Author
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Duthu, A., primary, Alexandrov, I., additional, Le Goffic, N., additional, and St Cyr, Ch.De Vaux, additional
- Published
- 1984
- Full Text
- View/download PDF
214. Lowest-order constrained variational method for simple many-fermion systems
- Author
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Alexandrov, I., primary, Moszkowski, S.A., additional, and Wong, C.W., additional
- Published
- 1975
- Full Text
- View/download PDF
215. A Study of the Superplastic Deformation Behavior of Low-Cost Ti-2Fe-0.1B Alloys.
- Author
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Mi, Yaoyao, Lu, Yu, Wang, Delong, Zhao, Yihui, Dong, Yuecheng, Chang, Hui, and Alexandrov, I. V.
- Subjects
- *
STRAIN rate , *DEFORMATIONS (Mechanics) , *ALLOYS , *TITANIUM alloys , *CRYSTAL lattices , *RECRYSTALLIZATION (Metallurgy) - Abstract
Titanium alloys have high specific strength and corrosion resistance, which have promising applications in industry. However, the machinability of titanium alloys is limited due to their crystal lattice and physical properties. Thus, in recent years, the superplastic forming of titanium alloys has been intensively developing, in particular, forming at low temperatures and/or high strain rates. In this work, a tensile test of low-cost Ti-2Fe-0.1B alloys was carried out at a temperature of 550~750 °C and a strain rate of 1 × 10−3 s−1~1 × 10−2 s−1. The results showed that the alloy exhibited good superplasticity even at a high strain rate (1 × 10−2 s−1) and a low deformation temperature of 550 °C; the elongation of the alloy in this state reached 137.5%. The high strain rate sensitivity coefficient m (0.3) and the maximum elongation (452%) were obtained at a strain rate of 1 × 10−3 s−1 and a temperature of 750 °C. Characteristics of the microstructure showed that during superplastic deformation, the recrystallization and grain boundary sliding of the alloy phases were accelerated, which could be ascribed to the effect of the element Fe. At the same time, the TiB phase located around the primary elongated α grains could also induce dynamic recrystallization and dynamic globularization during deformation. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
216. Process management inside ATLAS DAQ
- Author
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Alexandrov, I., primary, Amorim, A., additional, Badescu, E., additional, Burckhart-Chromek, D., additional, Caprini, M., additional, Dobson, M., additional, Duval, P.Y., additional, Hart, R., additional, Jones, R., additional, Kazarov, A., additional, Kolos, S., additional, Kotov, V., additional, Liko, D., additional, Lucio, L., additional, Mapelli, L., additional, Mineev, M., additional, Moneta, L., additional, Nassiakou, M., additional, Pedro, L., additional, Ribeiro, A., additional, Roumiantsev, V., additional, Ryabov, Y., additional, Schweiger, D., additional, Soloviev, I., additional, and Wolters, H., additional
- Full Text
- View/download PDF
217. 18p− Syndrome: an unusual case and diagnosis by in situ hybridization with chromosome 18-specific alphoid DNA sequence
- Author
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Vorsanova, Svetlana G., Yurov, Y. B., Alexandrov, I. A., Demidova, I. A., Mitkevich, S. P., and Tirskaia, A. F.
- Abstract
A patient with an atypical clinical picture of 18p
- syndrome is described. By the in situ hybridization technique we localized the chromosome 18-specific cloned repetitive sequence to metaphase chromosomes of the patient. The predominant hybridization of the probe was found in pericentromeric regions of homologous chromosomes 18. The amount of pericentromeric DNA measured by in situ hybridization differed between homologous chromosomes; and the number of radioactive grains was statistically greater in the normal chromosome 18 than in the aberrant chromosome 18p- . The results indicate that this probe may be useful in clinical cytogenetics for identification of aberrant chromosomes, localization of breakpoints, and studies of C-band DNA polymorphism of chromosome 18.- Published
- 1986
- Full Text
- View/download PDF
218. Grain boundary character distributions and mechanical properties of 304 stainless steel
- Author
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Mishin, O. V., Gertsman, V. Y., Alexandrov, I. V., and Valiev, R. Z.
- Published
- 1996
- Full Text
- View/download PDF
219. Process management inside ATLAS DAQ.
- Author
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Alexandrov, I., Amorim, A., Badescu, E., Burckhart-Chromek, D., Caprini, M., Dobson, M., Duval, P.Y., Hart, R., Jones, R., Kazarov, A., Kolos, S., Kotov, V., Liko, D., Lucio, L., Mapelli, L., Mineev, M., Moneta, L., Nassiakou, M., Pedro, L., and Ribeiro, A.
- Published
- 2001
- Full Text
- View/download PDF
220. Effect of Heat Treatment on Microstructure and Mechanical Behavior of Ultrafine-Grained Ti-2Fe-0.1B.
- Author
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Mi, Yaoyao, Wang, Yanhuai, Wang, Yu, Dong, Yuecheng, Chang, Hui, and Alexandrov, I. V.
- Subjects
- *
EFFECT of heat treatment on microstructure , *MECHANICAL heat treatment , *CRYSTAL grain boundaries , *RECRYSTALLIZATION (Metallurgy) , *TRANSMISSION electron microscopy - Abstract
In the present study, a novel Ti-2Fe-0.1B alloy was processed using equal channel angular pressing (ECAP) via route Bc for four passes. The isochronal annealing of the ultrafine-grained (UFG) Ti-2Fe-0.1B alloy was conducted at various temperatures between 150 and 750 °C with holding times of 60 min. The isothermal annealing was performed at 350–750 °C with different holding times (15 min–150 min). The results indicated that no obvious changes in the microhardness of the UFG Ti-2Fe-0.1B alloy are observed when the annealing temperature (AT) is up to 450 °C. Compared to the UFG state, it was found that excellent strength (~768 MPa) and ductility (~16%) matching can be achieved for the UFG Ti-2Fe-0.1B alloy when annealed at 450 °C. The microstructure of the UFG Ti-2Fe-0.1B alloy before and after the various annealing treatments was characterized using electron backscatter diffraction (EBSD) and transmission electron microscopy (TEM). It was found that the average grain size remained at an ultrafine level (0.91–1.03 μm) when the annealing temperature was below 450 °C. The good thermal stability of the UFG Ti-2Fe-0.1B alloy could be ascribed to the pinning of the TiB needles and the segregation of the Fe solute atoms at the grain boundaries, which is of benefit for decreasing grain boundary energy and inhibiting the mobility of grain boundaries. For the UFG Ti-2Fe-0.1B alloy, a recrystallization activation energy with an average value of ~259.44 KJ/mol was analyzed using a differential scanning calorimeter (DSC). This is much higher than the lattice self-diffusion activation energy of pure titanium. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
221. Mechanisms of high-speed deformation of polycrystalline copper.
- Author
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Chembarisova, R., Dong, Y., and Alexandrov, I.
- Subjects
- *
POLYCRYSTALS , *COPPER , *MATERIAL plasticity , *NUMERICAL analysis , *MACROSCOPIC films - Abstract
The mechanisms of high-speed deformation of ultrafine-grained copper produced during severe plastic deformation by equal-channel angular pressing were analyzed using numerical modeling in comparison with those in the case of coarse-crystalline copper. The activity of annihilation processes during nonconservative motion and double cross slip of dislocations was estimated. Their effect on the macroscopic behavior of samples is shown. [ABSTRACT FROM AUTHOR]
- Published
- 2017
- Full Text
- View/download PDF
222. Developing of SPD processing and enhanced properties in bulk nanostructured metals
- Author
-
Alexandrov, I
- Published
- 2001
- Full Text
- View/download PDF
223. Establishment of a new continuous cell line of Drosophila melanogaster strain infected by the intracellular endosymbiotic bacterium Wolbachia pipientis under natural conditions.
- Author
-
Andrianov, B. V., Goriacheva, I. I., Alexandrov, I. D., and Gorelova, T. V.
- Subjects
- *
DROSOPHILA melanogaster , *CELL lines , *WOLBACHIA , *AEDES albopictus , *TETRACYCLINE - Abstract
Wolbachia pipientis is an obligately intracellular bacterium infecting a number of arthropod and nematode species. At the body level, Wolbachia infection may cause parthenogenesis, feminization of genetic males, male killing, or cytoplasmic incompatibility; it may also be asymptomatic. Of special interest is DNA transfer from Wolbachia to the host insect genome, which was discovered recently. At the cellular level, the effects caused by Wolbachia have been studied more poorly. Only one of the known insect cell lines has been obtained from an insect species (the mosquito Aedes albopictus) infected by Wolbachia. In this study, a continuous cell line Dm2008Wb1 has been obtained from embryos of Drosophila melanogaster infected under natural conditions. Wolbachia both persists in a primary cell culture and is retained upon its transformation into a continuous culture. The presence of this bacterium in cells in a free form is evidenced by the fact that tetracycline treatment can cure the cells of Wolbachia and by successful transfer of Wolbachia to another cell line (S2), where it has not been detected before. [ABSTRACT FROM AUTHOR]
- Published
- 2010
- Full Text
- View/download PDF
224. Deployment and Use of the ATLAS DAQ in the Combined Test Beam.
- Author
-
Gadomski, S., Abolins, M., Alexandrov, I., Amorim, A., Padilla-Aranda, C., Badescu, E., Barros, N., Beck, H. P., Blair, R., Burckhart-Chromek, D., Caprini, M., Ciobotaru, M., Conde-Muino, P., Corso-Radu, A., Di Girolamo, B., Diaz-Gomez, M., Dobinson, R., Dobson, M., Ferrari, R., and Ferrer, M. L.
- Subjects
- *
LARGE Hadron Collider , *HADRON colliders , *SUPERCOLLIDERS , *COLLIDERS (Nuclear physics) , *PROTON accelerators , *HADRON facilities , *COMPUTER software , *COMPUTER systems , *ELECTRONICS - Abstract
The ATLAS collaboration at CERN operated a combined test beam (CTB) from May until November 2004. The prototype of ATLAS data acquisition system (DAQ) was used to integrate other subsystems into a common CTB setup. Data were collected synchronously from all the ATLAS detectors, which represented nine different detector technologies. Electronics and software of the first level trigger were used to trigger the setup. Event selection algorithms of the high level trigger were integrated with the system and were tested with real detector data. The possibility to operate a remote Event Filter farm synchronized with the ATLAS Trigger and Data Acquisition System (TDAQ) was also tested. Event data, as well as detector conditions data, were made available for offline analysis. [ABSTRACT FROM AUTHOR]
- Published
- 2006
- Full Text
- View/download PDF
225. ATLAS DataFlow: The Read-Out Subsystem, Results From Trigger and Data-Acquisition System Testbed Studies and From Modeling.
- Author
-
Vermeulen, J., Abolins, M., Alexandrov, I., Amorim, A., Dos Anjos, A., Badescu, B., Barros, N., Beck, H. P., Blair, R., Burckhart-Chromek, D., Caprini, M., Ciobotaru, M., Corso-Radu, A., Cranfield, R., Crone, G., Dawson, J., Dobinson, R., Dobson, M., Drake, G., and Ermoline, Y.
- Subjects
- *
ATLAS (Computer program language) , *DATA transmission systems , *NETWORK operating system , *COMPUTER architecture , *COMPUTERS , *DATABASE management , *DATABASE administration , *MATHEMATICAL optimization , *REAL-time computing - Abstract
In the ATLAS experiment at the LHC, the output of read-out hardware specific to each subdetector will be transmitted to buffers, located on custom made PCI cards ("ROBINs"). The data consist of fragments of events accepted by the first-level trigger at a maximum rate of 100 kHz. Groups of four ROBINs will be hosted in about 150 Read-Out Subsystem (ROS) PCs. Event data are forwarded on request via Gigabit Ethernet links and switches to the second-level trigger or to the Event builder. In this paper a discussion of the functionality and real-time properties of the ROS is combined with a presentation of measurement and modelling results for a testbed with a size of about 20% of the final DAQ system. Experimental results on strategies for optimizing the system performance, such as utilization of different network architectures and network transfer protocols, are presented for the testbed, together with extrapolations to the full system. [ABSTRACT FROM AUTHOR]
- Published
- 2006
- Full Text
- View/download PDF
226. Application of bulk nanostructured materials in medicine
- Author
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Latysh, V., Krallics, Gy., Alexandrov, I., and Fodor, A.
- Subjects
- *
TITANIUM , *FLUID mechanics , *HYDROSTATICS , *PERMEABILITY - Abstract
Abstract: Titanium alloys have been the mostly used materials of choice for medical implants. They are generally considered chemically inert, biocompatible with human tissue and resistant to corrosion by human body fluids. However the small percentages of vanadium and aluminum atoms (main alloying elements) contained in the alloy are potentially toxic. Normal wear can lead to deterioration of the implant and the release of alloying elements into the body. The novel process—a combination of severe plastic deformation with traditional metal forming process—can produce special material structure with nanosize grains. This nanostructured material has high tensile and fatique strength and even the enhanced ductility. Pure titanium is chemically and biologically more compatible with human fluids and tissue than other materials but the coarse-grained titanium is too weak for prostheses that must bear heavy loads such as leg or hipbone implants. The strength of pure titanium is less than half the strength of Ti–6Al–4V alloy what is mostly have used for medical implants. By using the mentioned novel process the strength of pure titanium with nanosize grains can be increased even higher than in case of the conventional Ti–6Al–4V alloy. This new process creates medical implants that are strong enough to bear heavy loads without failure. The implant material is corrosion resistant and biocompatible with human body organs and fluids so it can remain in the body for years. [Copyright &y& Elsevier]
- Published
- 2006
- Full Text
- View/download PDF
227. Investigation of the possibility of using x-ray sensitive lines detection technology in microfocus radiography.
- Author
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Larionov, I. A., Klonov, V. V., Staroverov, N. E., Kiselev, A. S., Alexandrov, I. V., Potrakhov, N N, Gryaznov, A Yu, and Kostrin, D K
- Subjects
- *
RADIOGRAPHY , *COMPUTER software development , *TECHNOLOGY , *POSSIBILITY , *X-rays - Abstract
The paper demonstrates the features of software development for CCD-lines X-CARD DE & SE manufactured by Detection Technology. The modes of operation of it in various states and their description are given. The article demonstrates the ability to create an X-ray detector based on the above CCD arrays. [ABSTRACT FROM AUTHOR]
- Published
- 2020
- Full Text
- View/download PDF
228. The ATLAS Data Acquisition and Trigger: concept, design and status
- Author
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Kordas, K., Abolins, M., Alexandrov, I., Amorim, A., Aracena, I., Armstrong, S., Badescu, E., Baines, J.T.M., Barros, N., Beck, H.P., Bee, C., Bellomo, M., Biglietti, M., Blair, R., Bogaerts, J.A.C., Bold, T., Bosman, M., Burckhart-Chromek, D., Caprini, M., and Caramarcu, C.
- Subjects
- *
DETECTORS , *PARTICLES (Nuclear physics) , *NUCLEAR physics , *PHYSICS - Abstract
This article presents the base-line design and implementation of the ATLAS Trigger and Data Acquisition system, in particular the Data Flow and High Level Trigger components. The status of the installation and commissioning of the system is also presented. [Copyright &y& Elsevier]
- Published
- 2007
- Full Text
- View/download PDF
229. Transformation of garnet megacrysts captured by alkali mafic magma.
- Author
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Aseeva, A., Vysotskiy, S., Karabtsov, A., Alexandrov, I., and Chuvashova, I.
- Subjects
- *
SYMPLECTIC groups , *BASALT , *ARCHAEOLOGICAL assemblages , *MAGMAS - Abstract
The results of research of symplectites from the Shavaryn-Tsaram (Hangaj plateau, Mongolia) and Bartoj (Dzhida basaltic field, Russia) alkali basaltic rocks are presented. The symplectite compositions and structures were studied, and the physical and chemical parameters at which primary megacrysts were transformed into secondary mineral assemblages were defined. It is established that both garnet megacrysts and garnet-clinopyroxene aggregates were formed at pressures of 10-13 kbar and temperatures over 1300°C. The transformation of garnet into minerals of the secondary assemblage is considered as solid state water assisted resorption of garnet at a depth corresponding to pressures of 4-8 kbar and temperatures ranging from 1000 to 1300°C. The kelyphitic rims on the garnet megacrysts resulted from melting of the megacrysts at the contact with the hosting alkali basaltic rock. [ABSTRACT FROM AUTHOR]
- Published
- 2014
- Full Text
- View/download PDF
230. Experimental Development of New Surgical Suturing Materials with Complex Biological Activities.
- Author
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Mokhov, E., Homullo, G., Sergeev, A., and Alexandrov, I.
- Subjects
- *
SUTURING , *SURGICAL equipment , *OPERATIVE surgery , *SUTURES , *LABORATORY rats , *GRANULATION tissue , *EQUIPMENT & supplies - Abstract
New surgical suturing materials with complex biological activities (antibacterial and stimulating tissue regeneration) have been developed. In vitro studies demonstrated pronounced and prolonged (up to 10-12 days) antibacterial activity. Experiments on 108 male albino rats proved the positive effect of the materials on the wound process: shortening of the inflammation period, more rapid transformation of the granulation tissue, more rapid epithelialization of the wound and its pronounced contraction. [ABSTRACT FROM AUTHOR]
- Published
- 2012
- Full Text
- View/download PDF
231. Geiger mode APD performance in a cryogenic two-phase Ar avalanche detector based on THGEMs
- Author
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Bondar, A., Buzulutskov, A., Grebenuk, A., Sokolov, A., Akimov, D., Alexandrov, I., and Breskin, A.
- Subjects
- *
AVALANCHE photodiodes , *DETECTORS , *LOW temperature engineering , *PHOTOMULTIPLIERS , *HOLES (Electron deficiencies) , *ARGON , *PHOTOELECTRONS , *EXTRAPOLATION , *GEIGER-Muller counters - Abstract
Abstract: Characteristic properties of a Geiger Mode APD (G-APD) in a THGEM-based cryogenic two-phase Ar avalanche detector were studied in view of potential applications in rare-event experiments. G-APD signal amplitude and noise characteristics at cryogenic temperatures turned out to be superior to those at room temperature. The effective detection of avalanche scintillations from THGEM-multiplier holes in two-phase Ar has been demonstrated using a G-APD without wavelength shifter. At an avalanche gain of 60, the avalanche scintillation yield measured by the G-APD was as high as 0.9 photoelectrons per avalanche electron, extrapolated to 4π acceptance. [ABSTRACT FROM AUTHOR]
- Published
- 2011
- Full Text
- View/download PDF
232. A Mechanism of Grain Nucleation during Relaxation of the Latent Energy of Junction Disclinations in the Course of Plastic Deformation.
- Author
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Orlova, T. S., Romanov, A. E., Nazarov, A. A., Enikeev, N. A., Alexandrov, I. V., and Valiev, R. Z.
- Subjects
- *
CRYSTAL grain boundaries , *CRYSTAL growth , *NUCLEATION , *PHYSICAL & theoretical chemistry , *RELAXATION phenomena - Abstract
A model describing the nucleation of a new grain at the boundary of an existing grain during relaxation of the latent energy of junction disclinations formed in the course of plastic deformation is considered. This nucleation mechanism is shown to be energetically favorable. The dependence of the equilibrium size and misorientation of a nucleus on its shape is analyzed. © 2005 Pleiades Publishing, Inc. [ABSTRACT FROM AUTHOR]
- Published
- 2005
- Full Text
- View/download PDF
233. Grain Size Refinement due to Relaxation of Disclination Junction Configurations in the Course of Plastic Deformation of Polycrystals.
- Author
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Orlova, T. S., Nazarov, A. A., Enikeev, N. A., Alexandrov, I. V., Valiev, R. Z., and Romanov, A. E.
- Subjects
- *
POLYCRYSTALS , *DEFORMATIONS (Mechanics) , *PLASTICS , *QUADRUPOLES , *INTERFACES (Physical sciences) , *CRYSTALS - Abstract
A model is proposed for the formation of the substructure in polycrystals during plastic deformation. According to this model, fragmentation of a grain occurs through the formation of a system of diagonal low-angle boundaries, which originate at the edges of a rectangular grain. Misorientation boundaries form through relaxation of a nonsymmetric junction quadrupole disclination configuration accumulated at the grain corners under severe deformation when the disclination strength reaches a certain critical value. The energetics of this process is analyzed. A general case is considered where the disclinations at the junctions of the chosen grain differ in strength. The energetic approach used makes it possible to determine the misorientation angle ωx of the resulting boundaries corresponding to the maximum energy gain and to find the dependence of this angle on the degree of asymmetry of the quadrupole configuration of junction disclinations. According to the proposed model, the splitting of a grain with a short edge greater than 0.5μm is energetically favorable and decreases the latent energy of the grain for any ratio between the junction disclination strengths if the grain length-to-width ratio is less than 30. It is shown that the minimum possible grain size in the proposed model does not exceed 0.1μm. © 2005 Pleiades Publishing, Inc. [ABSTRACT FROM AUTHOR]
- Published
- 2005
- Full Text
- View/download PDF
234. Passive and Active Target Delivery of Drugs to Ischemic Myocardium.
- Author
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Galagudza, M., Korolev, D., Sonin, D., Alexandrov, I., Minasian, S., Postnov, V., Kirpicheva, E., Papayan, G., and Uskov, I.
- Subjects
- *
MYOCARDIUM , *HEART , *SILICA , *SILICON compounds , *NANOPARTICLES - Abstract
Silica nanoparticles as carriers for targeted drug delivery to the heart were studied. Studies of hemodynamic parameters of rats after intravenous infusion of silica nanoparticles showed no acute toxicity. Intravenous infusion of silica nanoparticles to animals with ischemia−reperfusion of the myocardium led to accumulation of the nanoparticles in the focus of injury, which attests to possibility of passive targeted drug delivery to the myocardium. [ABSTRACT FROM AUTHOR]
- Published
- 2011
- Full Text
- View/download PDF
235. THE CALCULATION OF THE CONSTANT FOR NUCLEAR MAGNETIC SHIELDING
- Author
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Alexandrov, I
- Published
- 1958
236. MODEL THREE BODY PROBLEM.
- Author
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Alexandrov, I
- Published
- 1967
237. CYTOGENETIC RADIOSENSITIVITY OF MAMMAL MARROW CELLS IN DIFFERENTIAL PHASES OF THE CELL CYCLE IN VIVO
- Author
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Alexandrov, I
- Published
- 1966
238. Classification and monomer-by-monomer annotation dataset of suprachromosomal family 1 alpha satellite higher-order repeats in hg38 human genome assembly.
- Author
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Uralsky LI, Shepelev VA, Alexandrov AA, Yurov YB, Rogaev EI, and Alexandrov IA
- Abstract
In the latest hg38 human genome assembly, centromeric gaps has been filled in by alpha satellite (AS) reference models (RMs) which are statistical representations of homogeneous higher-order repeat (HOR) arrays that make up the bulk of the centromeric regions. We analyzed these models to compose an atlas of human AS HORs where each monomer of a HOR was represented by a number of its polymorphic sequence variants. We combined these data and HMMER sequence analysis platform to annotate AS HORs in the assembly. This led to discovery of a new type of low copy number highly divergent HORs which were not represented by RMs. These were included in the dataset. The annotation can be viewed as UCSC Genome Browser custom track (the HOR-track) and used together with our previous annotation of AS suprachromosomal families (SFs) in the same assembly, where each AS monomer can be viewed in its genomic context together with its classification into one of the 5 major SFs (the SF-track). To catalog the diversity of AS HORs in the human genome we introduced a new naming system. Each HOR received a name which showed its SF, chromosomal location and index number. Here we present the first installment of the HOR-track covering only the 17 HORs that belong to SF1 which forms live functional centromeres in chromosomes 1, 3, 5, 6, 7, 10, 12, 16 and 19 and also a large number of minor dead HOR domains, both homogeneous and divergent. Monomer-by-monomer HOR annotation used for this dataset as opposed to annotation of whole HOR repeats provides for mapping and quantification of various structural variants of AS HORs which can be used to collect data on inter-individual polymorphism of AS.
- Published
- 2019
- Full Text
- View/download PDF
239. Annotation of suprachromosomal families reveals uncommon types of alpha satellite organization in pericentromeric regions of hg38 human genome assembly.
- Author
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Shepelev VA, Uralsky LI, Alexandrov AA, Yurov YB, Rogaev EI, and Alexandrov IA
- Abstract
Centromeric alpha satellite (AS) is composed of highly identical higher-order DNA repetitive sequences, which make the standard assembly process impossible. Because of this the AS repeats were severely underrepresented in previous versions of the human genome assembly showing large centromeric gaps. The latest hg38 assembly (GCA_000001405.15) employed a novel method of approximate representation of these sequences using AS reference models to fill the gaps. Therefore, a lot more of assembled AS became available for genomic analysis. We used the PERCON program previously described by us to annotate various suprachromosomal families (SFs) of AS in the hg38 assembly and presented the results of our primary analysis as an easy-to-read track for the UCSC Genome Browser. The monomeric classes, characteristic of the five known SFs, were color-coded, which allowed quick visual assessment of AS composition in whole multi-megabase centromeres down to each individual AS monomer. Such comprehensive annotation of AS in the human genome assembly was performed for the first time. It showed the expected prevalence of the known major types of AS organization characteristic of the five established SFs. Also, some less common types of AS arrays were identified, such as pure R2 domains in SF5, apparent J/R and D/R mixes in SF1 and SF2, and several different SF4 higher-order repeats among reference models and in regular contigs. No new SFs or large unclassed AS domains were discovered. The dataset reveals the architecture of human centromeres and allows classification of AS sequence reads by alignment to the annotated hg38 assembly. The data were deposited here: http://genome.ucsc.edu/cgi-bin/hgTracks?db=hg38&hgt.customText=https://dl.dropboxusercontent.com/u/22994534/AS-tracks/human-GRC-hg38-M1SFs.bed.bz2.
- Published
- 2015
- Full Text
- View/download PDF
240. Regulation of actin cytoskeleton in lymphocytes: PKC-delta disrupts IL-3-induced membrane ruffles downstream of Rac1.
- Author
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Romanova LY, Alexandrov IA, Blagosklonny MV, Nordan RP, Garfield S, Acs P, Nguyen P, Trepel J, Blumberg PM, and Mushinski JF
- Subjects
- Animals, Cell Line, Cell Membrane drug effects, Cell Size drug effects, Cytochalasin D pharmacology, Cytoskeleton metabolism, Indoles pharmacology, Isoenzymes antagonists & inhibitors, Maleimides pharmacology, Mice, Phenotype, Protein Kinase C antagonists & inhibitors, Protein Kinase C-delta, Tetradecanoylphorbol Acetate pharmacology, Tubulin metabolism, rac GTP-Binding Proteins, Actins metabolism, B-Lymphocytes metabolism, GTP-Binding Proteins metabolism, Interleukin-3 pharmacology, Isoenzymes pharmacology, Protein Kinase C pharmacology
- Abstract
In the murine pre-B lymphoid cell line Baf3, the presence of IL-3 is required for the formation of membrane ruffles that intensely stain for actin and are responsible for the elongated cell phenotype. Withdrawal of IL-3 dissolves ruffled protrusions and converts the cell phenotype to round. Flow cytometric analysis of the cell shape showed that an inactive analog of Rac1 but not inactive RhoA or inactive cdc42 rounds the cells in the presence of IL-3. Constitutively activated Rac1 restores the elongated cell phenotype to IL-3-starved cells. We conclude that the activity of Rac1 is necessary and sufficient for the IL-3-induced assembly of membrane ruffles. Similar to the IL-3 withdrawal, phorbol 12-myristate 13-acetate (PMA) dissolves actin-formed membrane ruffles and rounds the cells in the presence of IL-3. Flow cytometric analysis of the cell shape demonstrated that in the presence of IL-3 the PMA-induced cell rounding cannot be abolished by constitutively active Rac1 but can be imitated by inactive Rac1. These data indicate that PMA disrupts the IL-3 pathway downstream of Rac1. Cells rounded by PMA return to the elongated phenotype concomitantly with PKC depletion. PMA-induced cell rounding can be reversed by the PKC-specific inhibitor GF109203X. Experiments with overexpression in Baf3 of individual PKC isoforms and a dominant negative PKC-delta indicate that activation of PKC-delta but not other PKC isoforms is responsible for disruption of membrane ruffles.
- Published
- 1999
- Full Text
- View/download PDF
241. Cross-talk between protein kinase C-alpha (PKC-alpha) and -delta (PKC-delta): PKC-alpha elevates the PKC-delta protein level, altering its mRNA transcription and degradation.
- Author
-
Romanova LY, Alexandrov IA, Nordan RP, Blagosklonny MV, and Mushinski JF
- Subjects
- Animals, Enzyme Activation drug effects, Enzyme Activation genetics, Enzyme Stability drug effects, Enzyme Stability genetics, Indoles pharmacology, Isoenzymes biosynthesis, Isoenzymes physiology, Leukemia, Promyelocytic, Acute, Lymphoma, B-Cell, Maleimides pharmacology, Mice, Protein Kinase C biosynthesis, Protein Kinase C physiology, Protein Kinase C-alpha, Protein Kinase C-delta, Tetradecanoylphorbol Acetate pharmacology, Tumor Cells, Cultured, Up-Regulation drug effects, Up-Regulation genetics, Isoenzymes genetics, Isoenzymes metabolism, Protein Kinase C genetics, Protein Kinase C metabolism, RNA, Messenger metabolism, Transcription, Genetic drug effects
- Abstract
Studies utilizing the overexpression of individual isoforms indicated that both PKC-alpha and -delta promote a number of biological effects, including inhibition of DNA synthesis associated with rearrangements of the actin cytoskeleton in the murine B-cell lymphoma (Baf3), differentiation of the murine promyelocyte line 32D, and activation of MAP kinase in CHO fibroblasts. We postulated that these results reflect some form of cross-regulation between PKC-alpha and -delta rather than their functional redundancy. In this report, we show that overexpression of PKC-alpha in Baf3 and 32D leads to an elevation of the endogenous PKC-delta mRNA and protein levels. The elevated steady-state PKC-delta mRNA level results from a combination of increased PKC-delta transcription and mRNA stability. Upregulation of PKC-delta mRNA by PKC-alpha occurs even after a selective depletion of the PKC-delta protein. In addition, phorbol ester-induced elevation of PKC-delta mRNA and protein levels can be prevented by the PKC inhibitor GF109203X, an indication of the requirement for PKC kinase activity. Inhibition of new protein synthesis by cycloheximide showed that upregulation of PKC-delta mRNA, as opposed to delayed downregulation of the PKC-delta protein, is primarily responsible for the accumulation of this isoform by PKC-alpha. In parental Baf3 and 32D cells and PKC-alpha overexpressers, PKC-alpha and PKC-delta are uniquely involved in cross-regulation, while PKC-epsilon, PKC-eta, and PKC-mu are not.
- Published
- 1998
- Full Text
- View/download PDF
242. Evidence for selection in evolution of alpha satellite DNA: the central role of CENP-B/pJ alpha binding region.
- Author
-
Romanova LY, Deriagin GV, Mashkova TD, Tumeneva IG, Mushegian AR, Kisselev LL, and Alexandrov IA
- Subjects
- Animals, Base Sequence, Centromere genetics, Centromere metabolism, Centromere Protein B, Chromosomal Proteins, Non-Histone metabolism, DNA, Satellite metabolism, DNA-Binding Proteins genetics, DNA-Binding Proteins metabolism, Molecular Sequence Data, Sequence Alignment, Sequence Analysis, Autoantigens, Chromosomal Proteins, Non-Histone genetics, DNA, Satellite genetics, Evolution, Molecular
- Abstract
Conservation of DNA segments performing sequence-related functions is a landmark of selection and functional significance. Phylogenetic variability of alpha satellite and apparent absence of conserved regions calls its functional significance into question, even though sequence-specific alpha satellite-binding proteins pJ alpha and CENP-B have been discovered. Moreover, the function of pJ alpha is obscure and CENP-B binding satellite DNA, which is thought to participate in centromere formation, is found only in few species and not necessarily in all chromosomes. Analysis of alpha satellite evolution allows us to recognize the order in this variability. Here we report a new alpha satellite suprachromosomal family, which together with the four defined earlier, covers all known alpha satellite sequences. Although each family has its characteristic types of monomers, they all descend from two prototypes, A and B. We show that most differences between prototypes are concentrated in a short region (positions 35 to 51), which exists in two alternative states: it matches a binding site for pJ alpha in type A and the one for CENP-B in type B. Lower primates have only type A monomers whereas great apes have both A and B. The new family is formed by monomeric types almost identical to A and B prototypes, thus representing a living relic of alpha satellite. Analysis of these data shows that selection-driven evolution, rather than random fixation of mutations, formed the distinction between A and B types. To our knowledge, this is the first evidence for selection in any of the known satellite DNAs.
- Published
- 1996
- Full Text
- View/download PDF
243. Mechanism of apoptosis suppression by phorbol ester in IL-6-starved murine plasmacytomas: role of PKC modulation and cell cycle.
- Author
-
Romanova LY, Alexandrov IA, Schwab G, Hilbert DM, Mushinski JF, and Nordan RP
- Subjects
- Alkaloids, Animals, Benzophenanthridines, Cell Line, Cytosol enzymology, Enzyme Activation, Enzyme Inhibitors pharmacology, Indoles pharmacology, Isoenzymes antagonists & inhibitors, Isoenzymes metabolism, Lactams pharmacology, Maleimides pharmacology, Mice, Phenanthridines pharmacology, Phorbol Esters pharmacology, Plasmacytoma, Protein Kinase C antagonists & inhibitors, Tetradecanoylphorbol Acetate analogs & derivatives, Tumor Cells, Cultured, Apoptosis drug effects, Cell Cycle drug effects, Interleukin-6 pharmacology, Protein Kinase C metabolism, Tetradecanoylphorbol Acetate pharmacology
- Abstract
We show here that the mode of cell death in IL-6-starved T1165 and T1198 plasmacytoma cell lines is apoptosis, and that it can be suppressed by phorbol ester (PMA) treatment in a protein kinase C (PKC)-mediated process that involves alpha and/or delta isozymes. PMA-induced PKC activation, but not the depletion that follows it, participates in the suppression of apoptosis. Extended PKC activation is necessary but not sufficient for the apoptosis suppression. In addition, the cells must be in a "competent" state, which appears not to be determined by PKC. We observed two points of "competence" during the time between withdrawal of IL-6 and the start of massive cell death: one, immediately after withdrawal, and another, just before onset of apoptosis, at the time corresponding to maximal accumulation of cells in a G0/G1 block imposed by IL-6 withdrawal. Treatment with PMA and other PKC activators resulted in a shift of the cell population to S phase, lifting the G0/G1 block. We propose a model in which cells are rescued in a certain stage of the G1 phase of cell cycle. Death suppression occurs when a transient PMA-induced PKC activation occurs when a significant number of cells are in this part of G1, allowing them to pass the restriction point safely without initiating the cell death program.
- Published
- 1996
- Full Text
- View/download PDF
244. Genomic organization, sequence and polymorphism of the human chromosome 4-specific alpha-satellite DNA.
- Author
-
Mashkova TD, Akopian TA, Romanova LY, Mitkevich SP, Yurov YB, Kisselev LL, and Alexandrov IA
- Subjects
- Base Sequence, Blotting, Southern, Humans, Molecular Sequence Data, Repetitive Sequences, Nucleic Acid, Sequence Homology, Nucleic Acid, Chromosomes, Human, Pair 4, DNA, Satellite genetics, Polymorphism, Restriction Fragment Length
- Abstract
Two alpha-satellite fragments specific for human chromosome 4 have been cloned and characterized. Under stringent annealing conditions, they hybridized in situ only to the pericentromeric region of chromosome 4, but under non-stringent conditions they hybridized to all chromosomes containing the sequences of alpha-satellite suprachromosomal family 2 (viz., chromosomes 2, 4, 8, 9, 13, 14, 15, 18, 20, 21 and 22). Southern blot analysis reveals the 3.2-kb higher-order repeated unit which exists in two forms: as a single MspI fragment or a combination of the 2.6-kb and 0.6-kb MspI fragments. The two chromosome-4-specific cloned sequences appear to be different parts of this repeated unit. Taken together they constitute about 60% of its length. The primary structure of the higher-order repeated unit is characterized by a dimeric periodicity of the D1-D2 type which is usual to suprachromosomal family 2. At least in one site this regularity is disrupted by monomer deletion leading to the D2-D2 monomeric order. The most likely mechanism of this monomer excision is homologous unequal crossing-over. These sequences may serve as both cytogenetic and restriction-fragment length polymorphism (RFLP) markers for the pericentromeric region of chromosome 4.
- Published
- 1994
- Full Text
- View/download PDF
245. Definition of a new alpha satellite suprachromosomal family characterized by monomeric organization.
- Author
-
Alexandrov IA, Medvedev LI, Mashkova TD, Kisselev LL, Romanova LY, and Yurov YB
- Subjects
- Animals, Base Sequence, Chlorocebus aethiops, Chromosomes, Human, Humans, Molecular Sequence Data, Sequence Homology, Nucleic Acid, DNA, Satellite genetics
- Abstract
We have analyzed more than 500 alphoid monomers either sequenced in our laboratory or available in the literature. Most of them belonged to the well studied suprachromosomal families 1, 2 and 3 characterized by dimeric (1 and 2) and pentameric (3) ancestral periodicities. The sequences that did not belong to the previously known families were subjected to further analysis. About a half of them formed a relatively homogenous family. Its members were on average 80.5% identical and 89.5% homologous to the M1 consensus sequence derived from this group (39 monomers). In the genome they do not form any ancestral periodicities other than a monomeric one, and are found at least in chromosomes 13, 14, 15, 21, 22 and Y. The newly defined family was termed suprachromosomal family 4. Comparison of all 10 alphoid monomeric groups identified so far showed that the M1 sequence is closely related to the J1-D2-W4-W5 homology grouping. Notably the African Green Monkey alpha satellite, also characterized by monomeric construction, appears to be a member of the same group.
- Published
- 1993
- Full Text
- View/download PDF
246. Chromosome-specific alpha satellites: two distinct families on human chromosome 18.
- Author
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Alexandrov IA, Mashkova TD, Akopian TA, Medvedev LI, Kisselev LL, Mitkevich SP, and Yurov YB
- Subjects
- Base Sequence, Humans, Molecular Sequence Data, Nucleic Acid Hybridization, Repetitive Sequences, Nucleic Acid, Sequence Homology, Nucleic Acid, Chromosomes, Human, Pair 18, DNA, Satellite genetics
- Abstract
Two types of human chromosome 18-specific alpha satellite fragments have been cloned and sequenced. They represent closely related but distinct alphoid families formed by two different types of the higher-order repeated units (1360-bp EcoRI and 1700-bp HindIII fragments) that do not alternate in the genome. The individual repeats within each family are 99% identical and interfamily homology is about 78%. Sequence analysis shows that both repeats belong to alphoid suprachromosomal family 2, but their homology is not higher than that of family members located on different chromosomes. Therefore, the two repeats shared a common origin in the recent past, although they are not the direct offspring of one ancestral sequence. Our data indicate that these two 18-specific domains have appeared as a result of two separate amplification events. Despite the high degree of homology, they are not undergoing intrachromosomal homogenization, although some variation of this process might take place within each domain.
- Published
- 1991
- Full Text
- View/download PDF
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