Search

Your search keyword '"Bishayee, Anupam"' showing total 1,020 results
Start Over Author "Bishayee, Anupam"
1,020 results on '"Bishayee, Anupam"'

210. Targeting IκappaB kinases for cancer therapy

Author

Awasthee, Nikee, primary, Rai, Vipin, additional, Chava, Srinivas, additional, Nallasamy, Palanisamy, additional, Kunnumakkara, Ajaikumar B., additional, Bishayee, Anupam, additional, Chauhan, Subhash C., additional, Challagundla, Kishore B., additional, and Gupta, Subash C., additional

Published
2019
Full Text
View/download PDF

220. Abyssinone V-4′ Methyl Ether, a Flavanone Isolated from Erythrina droogmansiana, Exhibits Cytotoxic Effects on Human Breast Cancer Cells by Induction of Apoptosis and Suppression of Invasion.

Author

Zingue, Stéphane, Gbaweng Yaya, Abel Joël, Cisilotto, Julia, Kenmogne, Larissa Vanelle, Talla, Emmanuel, Bishayee, Anupam, Njamen, Dieudonne, Creczynski-Pasa, Tânia Beatriz, and Ndinteh, Derek Tantoh

Subjects
REACTIVE oxygen species, APOPTOSIS, BREAST tumors, CANCER patients, CANCER invasiveness, CELL cycle, CELL lines, CELL surface antigens, CELLULAR signal transduction, FLOW cytometry, IMMUNODIAGNOSIS, MITOCHONDRIA, MOLECULAR structure, HEALTH outcome assessment, PLANT extracts, FLAVANONES
Abstract

Abyssinone V-4′ methyl ether (AVME) isolated from Erythrina droogmansiana was recently reported to exhibit anti-mammary tumor effect in mice. The present work was therefore aimed at elucidating its cellular and molecular mechanisms. To achieve our goal, the cytotoxicity of AVME against tumoral and non-tumoral cell lines was evaluated by resazurin reduction test; flow cytometry allowed us to evaluate the cell cycle and mechanisms of cell death; the mitochondrial transmembrane potential, reactive oxygen species (ROS) levels, and caspase activities as well as apoptosis-regulatory proteins (Bcl-2 and Bcl-XL) were measured in MDA-MB-231 cells. Further, the antimetastatic potential of AVME was evaluated by invasion assay. AVME exhibited cytotoxic effects in all tested tumor cell lines and induced a significant increase in the percentage of MDA-MB-231 cells at G2/M and S phases of the cell cycle in a concentration-dependent manner. AVME also induced apoptosis in MDA-MB-231 cells, which was accompanied by the activation of caspase-3 and caspase-9 and downregulation of Bcl-2 and Bcl-XL proteins. Moreover, AVME suppressed cancer cell invasion by the inhibition of the metalloproteinase-9 activity. Findings from this study suggest that AVME has anti-breast cancer activities expressed through mitochondrial proapoptotic pathway including impairment of aggressive behaviors of breast cancer cells. [ABSTRACT FROM AUTHOR]

Published
2020
Full Text
View/download PDF

221. Berberine, a popular dietary supplement for human and animal health: Quantitative research literature analysis – a review.

Author

Andy Wai Kan Yeung, Orhan, Ilkay Erdogan, Aggarwal, Bharat Bhushan, Battino, Maurizio, Belwal, Tarun, Bishayee, Anupam, Daglia, Maria, Devkota, Hari Prasad, El-Demerdash, Amr, Balacheva, Aneliya A., Georgieva, Maya G., Guptal, Vijai Kumar, Horbańczuk, Jarosław Olav, Jóźwik, Artur, Mozos, Ioana, Nabavi, Seyed Mohammad, Pittala, Valeria, Feder-Kubis, Joanna, Silva, Ana Sanches, and Sheridan, Helen

Subjects
DIETARY supplements, BERBERINE, QUANTITATIVE research, ANIMAL health, MOLECULAR biology, ALZHEIMER'S disease, ISOQUINOLINE alkaloids
Abstract

Berberine is an alkaloid with a wide range of reported beneficial health effects. The current work provides an extensive literature analysis on berberine. Bibliometric data were identified by means of the search string TOPIC=(“berberin*” OR “umbellatine*”), which yielded 5,547 publications indexed in the Web of Science Core Collection electronic database. The VOSviewer software generated bubble maps to visualize semantic terms with citation results. The ratio of original articles to reviews was 13.6:1. The literature has been growing more quickly since the 2010s. Major contributing countries were China, the United States, India, Japan, and South Korea. Most of the publications appeared in journals specialized in pharmacology pharmacy, biochemistry molecular biology, chemistry, and plant science. Some of the frequently mentioned chemicals/chemical classes were alkaloid, palmatine, jatrorrhizine, coptisine, isoquinoline, and sanguinarine. The prevalent medical conditions under investigation included Alzheimer’s disease, cancer, diabetes, and obesity. [ABSTRACT FROM AUTHOR]

Published
2020

223. Potential role of genipin in cancer therapy

Author

Shanmugam, Muthu K., primary, Shen, Hongyuan, additional, Tang, Feng Ru, additional, Arfuso, Frank, additional, Rajesh, Mohanraj, additional, Wang, Lingzhi, additional, Kumar, Alan Prem, additional, Bian, Jinsong, additional, Goh, Boon Cher, additional, Bishayee, Anupam, additional, and Sethi, Gautam, additional

Published
2018
Full Text
View/download PDF

228. Anthocyanins: Multi-Target Agents for Prevention and Therapy of Chronic Diseases

Author

Putta, Swathi, primary, Yarla, Nagendra S., additional, Peluso, Ilaria, additional, Tiwari, Dinesh K., additional, Reddy, Gorla V., additional, Giri, Priyanka V., additional, Kumar, Naresh, additional, Malla, Ramarao, additional, Rachel, Vijaya, additional, Bramhachari, P. Veera, additional, Reddy D, Rama S., additional, Bade, Ramesh, additional, Mannarapu, Mastan, additional, Barreto, George E., additional, Lu, Da-Yong, additional, Tarasov, Vadim V., additional, Chubarev, Vladimir N., additional, Ribeiro, Frederico F., additional, Scotti, Luciana, additional, Scotti, Marcus T., additional, Kamal, M.A., additional, Ashraf, Ghulam Md, additional, Aliev, Gjumrakch, additional, Perry, George, additional, Sarker, Satyajit D., additional, Rao, Chinthalapally V., additional, and Bishayee, Anupam, additional

Published
2018
Full Text
View/download PDF

229. Curcumin and Melanoma: From Chemistry to Medicine

Author

Nabavi, Seyed Mohammad, primary, Russo, Gian Luigi, additional, Tedesco, Idolo, additional, Daglia, Maria, additional, Orhan, Ilkay Erdogan, additional, Nabavi, Seyed Fazel, additional, Bishayee, Anupam, additional, Nagulapalli Venkata, Kalyan C., additional, Abdollahi, Mohammad, additional, and Hajheydari, Zohreh, additional

Published
2018
Full Text
View/download PDF

230. Potential Anticancer Properties of Osthol: A Comprehensive Mechanistic Review

Author

Shokoohinia, Yalda, primary, Jafari, Fataneh, additional, Mohammadi, Zeynab, additional, Bazvandi, Leili, additional, Hosseinzadeh, Leila, additional, Chow, Nicholas, additional, Bhattacharyya, Piyali, additional, Farzaei, Mohammad, additional, Farooqi, Ammad, additional, Nabavi, Seyed, additional, Yerer, Mükerrem, additional, and Bishayee, Anupam, additional

Published
2018
Full Text
View/download PDF

233. The Role of Resveratrol in Cancer Therapy

Author

Ko, Jeong-Hyeon, primary, Sethi, Gautam, additional, Um, Jae-Young, additional, Shanmugam, Muthu K, additional, Arfuso, Frank, additional, Kumar, Alan Prem, additional, Bishayee, Anupam, additional, and Ahn, Kwang Seok, additional

Published
2017
Full Text
View/download PDF

234. Diabetes Mellitus and Male Aging: Pharmacotherapeutics and Clinical Implications

Author

Putta, Swathi, primary, Peluso, Ilaria, additional, Yarla, Nagendra Sastry, additional, Kilari, Eswar Kumar, additional, Bishayee, Anupam, additional, Lu, Da-Yong, additional, Barreto, George E., additional, Ashraf, Ghulam Md, additional, Scotti, Luciana, additional, Scotti, Marcus T., additional, Singla, Rajeev K., additional, Alexiou, Thonos, additional, Atanasov, Atanas G., additional, Tarasov, Vadim V., additional, Bramhachari, P. Veera, additional, Imandi, Sarat Babu, additional, Chintala, Madhuri, additional, Sharma, Bechan, additional, Reale, Marcella, additional, Filosa, Rosanna, additional, Aliev, Gjumrakch, additional, and Kamal, Mohammad Amjad, additional

Published
2017
Full Text
View/download PDF

240. Natural Products Targeting Clinically Relevant Enzymes of Eicosanoid Biosynthesis Implicated in Inflammation and Cancer

Author

Reddy, Gorla V., primary, Yarla, Nagendra S., additional, Ediga, Shobha, additional, Tiwari, Dinesh K., additional, Kumar, Naresh, additional, Singh, Sandhya, additional, Bhandari, Vasundhra, additional, Giri, Priyanka Voori, additional, Bishayee, Anupam, additional, Rao, Chintalapally V., additional, and Reddanna, Pallu, additional

Published
2017
Full Text
View/download PDF

242. Ginkgolic Acids Confer Potential Anticancer Effects by Targeting Pro- Inflammatory and Oncogenic Signaling Molecules

Author

Shanmugam, Muthu K., Garg, Manoj, Makhija, Pooja, Kumar, Alan P., Sharifi-Rad, Javad, Zam, Wissam, and Bishayee, Anupam

Abstract

Background: Medicinal plants and herbal preparations in the form of traditional medicines have been used in healthcare worldwide. The extracts of Ginkgo biloba L. seeds and leaves contain a complex mixture of numerous components, such as flavonol glycosides, terpene lactones, and a group of alkylphenols (anacardic or ginkgolic acids, cardanols and cardols) that have been a part of traditional Chinese medicine. These extracts are also sold as dietary supplements worldwide. G. biloba extract (EGb 761 and LI 1370) represent the standard form of G. biloba extract. Six different 6-alkylsalicylic acids (syn. ginkgolic acids) with alkyl substituents (C13:0, C15:0, C15:1, C17:0, C17:1, and C17:2) have been identified. Objective: The aim of this review is to unravel scientific evidence on anti-inflammatory and anticancer activities of ginkgolic acids to understand its therapeutic potential against inflammatory and oncologic diseases. Methods: A structured literature search was independently performed by the authors on PubMed, ScienceDirect, Scopus, and Web of Science. Accordingly, this review article critically analyses available scientific evidence on anti-inflammatory and anticancer activities of ginkgolic acids. Moreover, the review only included articles written in the English language. Results: Several forms of ginkgolic acids, especially C13:0, C15:0 and C17:1, isolated from the leaves of G. biloba exhibited cytotoxic activity against a variety of human cancers by suppressing various pro-inflammatory signaling cascades and oncogenic transcription factors through multiple modes of action in various in vitro and in vivo preclinical models. Ginkgolic acids have also been reported to be potent post-translational small ubiquitin-related modifiers (SUMO)ylation inhibitors. Conclusion: In this review, we present updated information on the anti-inflammatory and anticancer properties of ginkgolic acids both in vitro and in vivo. Although ginkgolic acids show significant therapeutic potential in inflammatory and oncologic diseases, more investigations regarding the safety and efficacy of these natural agents are warranted before the clinical transition.

Published
2021
Full Text
View/download PDF

243. Ficus umbellata Vahl. (Moraceae) Stem Bark Extracts Exert Antitumor Activities In Vitro and In Vivo

Author

Silihe, Kevine, primary, Zingue, Stéphane, additional, Winter, Evelyn, additional, Awounfack, Charline, additional, Bishayee, Anupam, additional, Desai, Nishil, additional, João Mello, Leônidas, additional, Michel, Thomas, additional, Tankeu, Francine, additional, Ndinteh, Derek, additional, Honorine Riwom, Sara, additional, Njamen, Dieudonné, additional, and Creczynski-Pasa, Tânia, additional

Published
2017
Full Text
View/download PDF

248. Butein in health and disease: A comprehensive review

Author

Padmavathi, Ganesan, primary, Roy, Nand Kishor, additional, Bordoloi, Devivasha, additional, Arfuso, Frank, additional, Mishra, Srishti, additional, Sethi, Gautam, additional, Bishayee, Anupam, additional, and Kunnumakkara, Ajaikumar B., additional

Published
2017
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results