13,569 results on '"Chang, Won"'
Search Results
202. Optimal timing for drug delivery into the hippocampus by focused ultrasound: A comparison of hydrophilic and lipophilic compounds
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Seo, Younghee, Chang, Kyung Won, Lee, Jihyeon, Kong, Chanho, Shin, Jaewoo, Chang, Jin Woo, Na, Young Cheol, and Chang, Won Seok
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- 2024
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203. Mapping the low tolerance factor Bi(Li1/3Zr2/3)O3 end member and MPB composition nexus in Bi1/2Na1/2TiO3-based ceramics
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Ali, Sabir, Sheeraz, Muhammad, Ullah, Aman, Yun, Won Seok, Ullah, Amir, Kim, Ill Won, and Ahn, Chang Won
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- 2024
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204. An Anatomically Complicated Living Donor Kidney Transplantation from Hepatitis B Surface Antigen-Positive Donor to Negative Recipient With Size Discrepancy
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Park, Jeong Hyun, Shin, Young-Heun, and Chang, Won-Bae
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- 2024
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205. Large electrostrictive response via tailoring ergodic relaxor state in Bi1/2Na1/2TiO3-based ceramics with Bi(Mn1/2Ce1/2)O3 end-member
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Ullah Khan, Naimat, Yun, Won Seok, Ullah, Aman, Ali, Sabir, Sheeraz, Muhammad, Ullah, Amir, Kim, Ill Won, and Ahn, Chang Won
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- 2024
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206. Integrated assessment of the natural purification capacity of tidal flat for persistent toxic substances and heavy metals in contaminated sediments
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Kim, Taewoo, Lee, Changkeun, Kwon, Inha, Lee, Junghyun, Park, Shin Yeong, Kim, Dong-U, Lee, Jongmin, Jin, Gayoung, Yousefzadeh, Mehdi, Bae, Hanna, Yoo, Yeonjae, Kim, Jae-Jin, Noh, Junsung, Hong, Seongjin, Kwon, Bong-Oh, Chang, Won Keun, Chang, Gap Soo, and Khim, Jong Seong
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- 2024
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207. ATOMS:ALMA Three-millimeter Observations of Massive Star-forming regions -- III :Catalogues of candidate hot molecular cores and Hyper/Ultra compact HII regions
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Liu, Hong-Li, Liu, Tie, Evans, Neal J., Wang, Ke, Garay, Guido, Qin, Sheng-Li, Li, Shanghuo, Stutz, Amelia, Goldsmith, Paul F., Liu, Sheng-Yuan, Tej, Anandmayee, Zhang, Qizhou, Juvela, Mika, Li, Di, Wang, Jun-Zhi, Bronfman, Leonardo, Ren, Zhiyuan, Wu, Yue-Fang, Kim, Kee-Tae, Lee, Chang-Won, Tatematsu, Kenichi, Cunningham, Maria. R., Liu, Xun-Chuan, Wu, Jing-Wen, Hirota, Tomoya, Lee, Jeong-Eun, Li, Pak-Shing, Kang, Sung-Ju, Mardones, Diego, Ristorcelli, Isabelle, Zhang, Yong, Luo, Qiu-Yi, Toth, L. Viktor, Yi, Hee-weon, Yun, Hyeong-Sik, Peng, Ya-Ping, Li, Juan, Zhu, Feng-Yao, Shen, Zhi-Qiang, Baug, Tapas, Dewangan, Lokesh, Chakali, Eswaraiah, Liu, Rong, Xu, Feng-Wei, Wang, Yu, Zhang, Chao, Li, Jinzeng, Zhou, Jianwen, Tang, Mengyao, Xue, Qiaowei, Issac, Namitha, Soam, Archana, and Alvarez-Gutierrez, Rodrigo H.
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Astrophysics - Astrophysics of Galaxies ,Astrophysics - Solar and Stellar Astrophysics - Abstract
We have identified 453 compact dense cores in 3 mm continuum emission maps in the ATOMS (ALMA Three-millimeter Observations of Massive Star-forming regions) survey, and compiled three catalogues of high-mass star forming cores. One catalogue, referred to as H/UC-HII catalogue, includes 89 cores that enshroud hyper/ultra compact (H/UC) HII regions as characterized by associated compact H40alpha emission. A second catalogue, referred to as pure s-cHMC, includes 32 candidate Hot Molecular Cores (HMCs) showing rich spectra (N>20lines) of complex organic molecules (COMs) but not associated with H/UC-HII regions. The third catalogue, referred to as pure w-cHMC, includes 58 candidate HMCs with relatively low levels of COM richness and not associated with H/UC-HII regions. These three catalogues of dense cores provide an important foundation for future studies of the early stages of high-mass star formation across the Milky Way. We also find that nearly half of H/UC-HII cores are candidate HMCs. From the number counts of COM-containing and H/UC-HII cores, we suggest that the duration of high-mass protostellar cores showing chemically rich features is at least comparable to the lifetime of H/UC-HII regions. For cores in the H/UC-HII catalogue, the width of the H40alpha line increases as the core size decreases, suggesting that the non-thermal dynamical and/or pressure line-broadening mechanisms dominate on the smaller scales of the H/UC-HII cores., Comment: 17 pages, five tables, and 11 figures. Accepted for publication at MNRAS
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- 2021
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208. A Low-mass Cold and Quiescent Core Population in a Massive Star Protocluster
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Li, Shanghuo, Lu, Xing, Zhang, Qizhou, Lee, Chang-Won, Sanhueza, Patricio, Beuther, Henrik, Izaskun, Jiménez-Serra, Qiu, Keping, Palau, Aina, Feng, Siyi, Pillai, Thushara, Kim, Kee-Tae, Liu, Hong-Li, Girart, Josep Miquel., Liu, Tie, Wang, Junzhi, Wang, Ke, Liu, Hauyu Baobab, Smith, Howard A., Li, Di, Lee, Jeong-Eun, Li, Fei, Li, Juan, Kim, Shinyoung, Yue, Nannan, and Strom, Shaye
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Astrophysics - Astrophysics of Galaxies - Abstract
Pre-stellar cores represent the initial conditions of star formation. Although these initial conditions in nearby low-mass star-forming regions have been investigated in detail, such initial conditions remain vastly unexplored for massive star-forming regions. We report the detection of a cluster of low-mass starless and pre-stellar core candidates in a massive star protocluster forming cloud, NGC6334S. With the ALMA observations at a $\sim$0.02 pc spatial resolution, we identified 17 low-mass starless core candidates that do not show any evidence of protostellar activity. These candidates present small velocity dispersions, high fractional abundances of NH$_{2}$D, high NH$_{3}$ deuterium fractionations, and are completely dark in the infrared wavelengths from 3.6 up to 70~$\mu$m. Turbulence is significantly dissipated and the gas kinematics are dominated by thermal motions toward these candidates. Nine out of the 17 cores are gravitationally bound, and therefore are identified as pre-stellar core candidates. The embedded cores of NGC6334S show a wide diversity in masses and evolutionary stages., Comment: 13 pages, 4 figures, accepted for publication in ApJ Letters
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- 2021
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209. The JCMT BISTRO-2 Survey: The Magnetic Field in the Center of the Rosette Molecular Cloud
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Könyves, Vera, Ward-Thompson, Derek, Pattle, Kate, Di Francesco, James, Arzoumanian, Doris, Chen, Zhiwei, Diep, Pham Ngoc, Eswaraiah, Chakali, Fanciullo, Lapo, Furuya, Ray S., Hoang, Thiem, Hull, Charles L. H., Hwang, Jihye, Johnstone, Doug, Kang, Ji-hyun, Karoly, Janik, Kirchschlager, Florian, Kirk, Jason M., Koch, Patrick M., Kwon, Jungmi, Lee, Chang Won, Onaka, Takashi, Robitaille, Jean-François, Soam, Archana, Tahani, Mehrnoosh, Tang, Xindi, Tamura, Motohide, Berry, David, Bastien, Pierre, Ching, Tao-Chung, Coudé, Simon, Kwon, Woojin, Wang, Jia-Wei, Hasegawa, Tetsuo, Lai, Shih-Ping, and Qiu, Keping
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Astrophysics - Astrophysics of Galaxies ,Astrophysics - Solar and Stellar Astrophysics - Abstract
We present the first 850 $\mu$m polarization observations in the most active star-forming site of the Rosette Molecular Cloud (RMC, $d\sim$1.6 kpc) in the wall of the Rosette Nebula, imaged with the SCUBA-2/POL-2 instruments of the JCMT, as part of the B-Fields In Star-Forming Region Observations 2 (BISTRO-2) survey. From the POL-2 data we find that the polarization fraction decreases with the 850 $\mu$m continuum intensity with $\alpha$ = 0.49 $\pm$ 0.08 in the $p \propto I^{\rm -\alpha}$ relation, which suggests that some fraction of the dust grains remain aligned at high densities. The north of our 850 $\mu$m image reveals a "gemstone ring" morphology, which is a $\sim$1 pc-diameter ring-like structure with extended emission in the "head" to the south-west. We hypothesize that it might have been blown by feedback in its interior, while the B-field is parallel to its circumference in most places. In the south of our SCUBA-2 field the clumps are apparently connected with filaments which follow Infrared Dark Clouds (IRDCs). Here, the POL-2 magnetic field orientations appear bimodal with respect to the large-scale Planck field. The mass of our effective mapped area is $\sim$ 174 $M_\odot$ that we calculate from 850 $\mu$m flux densities. We compare our results with masses from large-scale emission-subtracted Herschel 250 $\mu$m data, and find agreement within 30%. We estimate the POS B-field strength in one typical subregion using the Davis-Chandrasekhar-Fermi (DCF) technique and find 80 $\pm$ 30 $\mu$G toward a clump and its outskirts. The estimated mass-to-flux ratio of $\lambda$ = 2.3 $\pm$ 1.0 suggests that the B-field is not sufficiently strong to prevent gravitational collapse in this subregion., Comment: 15 pages (12+3), 9 figures, 1 table. Accepted for publication in the Astrophysical Journal
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- 2021
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210. The JCMT BISTRO Survey: The Distribution of Magnetic Field Strengths towards the OMC-1 Region
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Hwang, Jihye, Kim, Jongsoo, Pattle, Kate, Kwon, Woojin, Sadavoy, Sarah, Koch, Patrick M., Hull, Charles L. H., Johnstone, Doug, Furuya, Ray S., Lee, Chang Won, Arzoumanian, Doris, Tahani, Mehrnoosh, Eswaraiah, Chakali, Liu, Tie, Kirchschlager, Florian, Kim, Kee-Tae, Tamura, Mothohide, Kwon, Jungmi, Lyo, A-Ran, Soam, Archana, Kang, Ji-hyun, Bourke, Tyler L., Matsumura, Masafumi, Mairs, Steve, Kim, Gwanjeong, Park, Geumsook, Nakamura, Fumitaka, Onaka, Takashi, Tang, Xindi, Liu, Hong-Li, Ward-Thompson, Derek, Li, Di, Hoang, Thiem, Hasegawa, Tetsuo, Qiu, Keping, Lai, Shih-Ping, and Bastien, Pierre
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Astrophysics - Astrophysics of Galaxies - Abstract
Measurement of magnetic field strengths in a molecular cloud is essential for determining the criticality of magnetic support against gravitational collapse. In this paper, as part of the JCMT BISTRO survey, we suggest a new application of the Davis-Chandrasekhar-Fermi (DCF) method to estimate the distribution of magnetic field strengths in the OMC-1 region. We use observations of dust polarization emission at 450 $\mu$m and 850 $\mu$m, and C$^{18}$O (3-2) spectral line data obtained with the JCMT. We estimate the volume density, the velocity dispersion and the polarization angle dispersion in a box, 40$''$ $\times$ 40$''$ (5$\times$5 pixels), which moves over the OMC-1 region. By substituting three quantities in each box to the DCF method, we get magnetic field strengths over the OMC-1 region. We note that there are very large uncertainties in inferred field strengths, as discussed in detail in this paper. The field strengths vary from 0.8 to 26.4 mG and their mean value is about 6 mG. Additionally, we obtain maps of the mass-to-flux ratio in units of a critical value and the Alfv$\acute{e}$n mach number. The central parts of the BN-KL and South (S) clumps in the OMC-1 region are magnetically supercritical, so the magnetic field cannot support the clumps against gravitational collapse. However, the outer parts of the region are magnetically subcritical. The mean Alfv$\acute{e}$n mach number is about 0.4 over the region, which implies that the magnetic pressure exceeds the turbulent pressure in the OMC 1 region., Comment: 28 pages
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- 2021
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211. Revealing the diverse magnetic field morphologies in Taurus dense cores with sensitive sub-millimeter polarimetry
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Eswaraiah, Chakali, Li, Di, Furuya, Ray S., Hasegawa, Tetsuo, Ward-Thompson, Derek, Qiu, Keping, Ohashi, Nagayoshi, Pattle, Kate, Sadavoy, Sarah, Hull, Charles L. H., Berry, David, Doi, Yasuo, Ching, Tao-Chung, Lai, Shih-Ping, Wang, Jia-Wei, Koch, Patrick M., Kwon, Jungmi, Kwon, Woojin, Bastien, Pierre, Arzoumanian, Doris, Coudé, Simon, Soam, Archana, Fanciullo, Lapo, Yen, Hsi-Wei, Liu, Junhao, Hoang, Thiem, Chen, Wen Ping, Shimajiri, Yoshito, Liu, Tie, Chen, Zhiwei, Li, Hua-bai, Lyo, A-Ran, Hwang, Jihye, Johnstone, Doug, Rao, Ramprasad, Ngoc, Nguyen Bich, Diep, Pham Ngoc, Mairs, Steve, Parsons, Harriet, Tamura, Motohide, Tahani, Mehrnoosh, Chen, Huei-Ru Vivien, Nakamura, Fumitaka, Shinnaga, Hiroko, Tang, Ya-Wen, Cho, Jungyeon, Lee, Chang Won, Inutsuka, Shu-ichiro, Inoue, Tsuyoshi, Iwasaki, Kazunari, Qian, Lei, Xie, Jinjin, Li, Dalei, Liu, Hong-Li, Zhang, Chuan-Peng, Chen, Mike, Zhang, Guoyin, Zhu, Lei, Zhou, Jianjun, André, Philippe, Liu, Sheng-Yuan, Yuan, Jinghua, Lu, Xing, Peretto, Nicolas, Bourke, Tyler L., Byun, Do-Young, Dai, Sophia, Duan, Yan, Duan, Hao-Yuan, Eden, David, Matthews, Brenda, Fiege, Jason, Fissel, Laura M., Kim, Kee-Tae, Lee, Chin-Fei, Kim, Jongsoo, Pyo, Tae-Soo, Choi, Yunhee, Choi, Minho, Chrysostomou, Antonio, Chung, Eun Jung, Tram, Le Ngoc, Franzmann, Erica, Friberg, Per, Friesen, Rachel, Fuller, Gary, Gledhill, Tim, Graves, Sarah, Greaves, Jane, Griffin, Matt, Gu, Qilao, Han, Ilseung, Hatchell, Jennifer, Hayashi, Saeko, Houde, Martin, Kawabata, Koji, Jeong, Il-Gyo, Kang, Ji-hyun, Kang, Sung-ju, Kang, Miju, Kataoka, Akimasa, Kemper, Francisca, Rawlings, Mark, Rawlings, Jonathan, Retter, Brendan, Richer, John, Rigby, Andrew, Saito, Hiro, Savini, Giorgio, Scaife, Anna, Seta, Masumichi, Kim, Gwanjeong, Kim, Kyoung Hee, Kim, Mi-Ryang, Kirchschlager, Florian, Kirk, Jason, Kobayashi, Masato I. N., Konyves, Vera, Kusune, Takayoshi, Lacaille, Kevin, Law, Chi-Yan, Lee, Sang-Sung, Lee, Yong-Hee, Matsumura, Masafumi, Moriarty-Schieven, Gerald, Nagata, Tetsuya, Nakanishi, Hiroyuki, Onaka, Takashi, Park, Geumsook, Tang, Xindi, Tomisaka, Kohji, Tsukamoto, Yusuke, Viti, Serena, Wang, Hongchi, Whitworth, Anthony, Yoo, Hyunju, Yun, Hyeong-Sik, Zenko, Tetsuya, Zhang, Yapeng, de Looze, Ilse, Dowell, C. Darren, Eyres, Stewart, Falle, Sam, Robitaille, Jean-François, and van Loo, Sven
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Astrophysics - Astrophysics of Galaxies - Abstract
We have obtained sensitive dust continuum polarization observations at 850 $\mu$m in the B213 region of Taurus using POL-2 on SCUBA-2 at the James Clerk Maxwell Telescope (JCMT), as part of the BISTRO (B-fields in STar-forming Region Observations) survey. These observations allow us to probe magnetic field (B-field) at high spatial resolution ($\sim$2000 au or $\sim$0.01 pc at 140 pc) in two protostellar cores (K04166 and K04169) and one prestellar core (Miz-8b) that lie within the B213 filament. Using the Davis-Chandrasekhar-Fermi method, we estimate the B-field strengths in K04166, K04169, and Miz-8b to be 38$\pm$14 $\mu$G, 44$\pm$16 $\mu$G, and 12$\pm$5 $\mu$G, respectively. These cores show distinct mean B-field orientations. B-field in K04166 is well ordered and aligned parallel to the orientations of the core minor axis, outflows, core rotation axis, and large-scale uniform B-field, in accordance with magnetically regulated star formation via ambipolar diffusion taking place in K04166. B-field in K04169 is found to be ordered but oriented nearly perpendicular to the core minor axis and large-scale B-field, and not well-correlated with other axes. In contrast, Miz-8b exhibits disordered B-field which show no preferred alignment with the core minor axis or large-scale field. We found that only one core, K04166, retains a memory of the large-scale uniform B-field. The other two cores, K04169 and Miz-8b, are decoupled from the large-scale field. Such a complex B-field configuration could be caused by gas inflow onto the filament, even in the presence of a substantial magnetic flux., Comment: 20 pages (10 are main), 5 figures (3 are main), and 3 tables (2 are main); Accepted for its publication in ApJL
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- 2021
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212. Incidence of Altered Level of Consciousness in Hemorrhagic Stroke Survivors: Associated Factors From a Korean Nationwide Study
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Ko, Nayeon, Lee, Hyun Haeng, Sohn, Min Kyun, Kim, Deog Young, Shin, Yong-Il, Oh, Gyung-Jae, Lee, Yang-Soo, Joo, Min Cheol, Lee, So Young, Song, Min-Keun, Han, Junhee, Ahn, Jeonghoon, Chang, Won Hyuk, Lee, Jongmin, and Kim, Yun-Hee
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- 2024
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213. Gas infalling motions in the envelopes of Very Low Luminosity Objects
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Kim, Mi-Ryang, Lee, Chang Won, Maheswar, Myers, Philip C., and Kim, Gwanjeong
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Astrophysics - Astrophysics of Galaxies ,Astrophysics - Solar and Stellar Astrophysics - Abstract
We present the results of a single dish survey toward 95 VeLLOs in optically thick (HCN 1-0) and thin ($\rm N_2H^+$ 1-0) lines performed for the purpose of understanding the physical processes of inward motions in the envelopes of the VeLLOs and characterizing their true nature. The normalized velocity differences ($\delta V_{HCN}$) between the peak velocities of the two lines were derived for 41 VeLLOs detected in both lines. The $\delta V$ distribution of these VeLLOs is found to be significantly skewed to the blue, indicating the dominance of infalling motions in their envelopes. The infall speeds were derived for 15 infall candidates by using the HILL5 radiative transfer model. The speeds were in the range of 0.03 $\rm km~s^{-1}$ to 0.3 $\rm km~s^{-1}$, with a median value of 0.16 $\rm km~s^{-1}$, being consistent with the gravitational free-fall speeds from pressure-free envelopes. The mass infall rates calculated from the infall speeds are mostly of the order of $10^{-6} M_{\odot}~yr^{-1}$ with a median value of $\rm 3.4 \pm 1.5 \times 10^{-6} M_{\odot}~yr^{-1}$. These are found to be also consistent with the values predicted with the inside-out collapse model and show a fairly good correlation with the internal luminosities of the VeLLOs. This again indicates that the infall motions observed toward the VeLLOs are likely to be due to the gravitational infall motions in their envelopes. Our study suggests that most of the VeLLOs are potentially faint protostars while two of the VeLLOs could possibly be proto-brown dwarf candidates.
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- 2021
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214. Fast and accurate learned multiresolution dynamical downscaling for precipitation
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Wang, Jiali, Liu, Zhengchun, Foster, Ian, Chang, Won, Kettimuthu, Rajkumar, and Kotamarthi, Rao
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Computer Science - Machine Learning ,Computer Science - Artificial Intelligence ,Statistics - Applications - Abstract
This study develops a neural network-based approach for emulating high-resolution modeled precipitation data with comparable statistical properties but at greatly reduced computational cost. The key idea is to use combination of low- and high- resolution simulations to train a neural network to map from the former to the latter. Specifically, we define two types of CNNs, one that stacks variables directly and one that encodes each variable before stacking, and we train each CNN type both with a conventional loss function, such as mean square error (MSE), and with a conditional generative adversarial network (CGAN), for a total of four CNN variants. We compare the four new CNN-derived high-resolution precipitation results with precipitation generated from original high resolution simulations, a bilinear interpolater and the state-of-the-art CNN-based super-resolution (SR) technique. Results show that the SR technique produces results similar to those of the bilinear interpolator with smoother spatial and temporal distributions and smaller data variabilities and extremes than the original high resolution simulations. While the new CNNs trained by MSE generate better results over some regions than the interpolator and SR technique do, their predictions are still not as close as the original high resolution simulations. The CNNs trained by CGAN generate more realistic and physically reasonable results, better capturing not only data variability in time and space but also extremes such as intense and long-lasting storms. The new proposed CNN-based downscaling approach can downscale precipitation from 50~km to 12~km in 14~min for 30~years once the network is trained (training takes 4~hours using 1~GPU), while the conventional dynamical downscaling would take 1~month using 600 CPU cores to generate simulations at the resolution of 12~km over contiguous United States.
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- 2021
215. Brand anthropomorphism on Twitter: communication strategies and consumer engagement
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Wu, Linwan, Dodoo, Naa Amponsah, and Choi, Chang-Won
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- 2023
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216. Ameliorative Effects of HT074-Inula and Paeonia Extract Mixture on Acute Reflux Esophagitis in Rats via Antioxidative Activity
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Young-Sik Kim, Yeonjin Park, Yongbin Kim, Hyo-Eun Son, Jinhui Rhee, Chang-Won Pyun, Chanoh Park, and Hocheol Kim
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antioxidative activity ,gastroesophageal reflux disease ,HT074 ,Inula britannica ,Paeonia lactiflora ,Therapeutics. Pharmacology ,RM1-950 - Abstract
HT074, a multiherbal mixture containing extracts from Inula britannica flowers and Paeonia lactiflora roots, is used in Korean medicine for gastric disorders. This study investigated the protective mechanisms of HT074 against acute reflux esophagitis (RE) in rats. Nitric oxide (NO) production and mRNA expression of antioxidant-related genes (Nrf2, HO-1, SOD, CAT, and GPx2) were evaluated in LPS-induced RAW 264.7 cells. Gastroesophageal reflux (GER) was induced in rats, followed by HT074 (100, 300 mg/kg) or ranitidine (50 mg/kg) administration. Esophageal damage and histological changes were assessed. Gastric pH and protein expression levels of Nrf2, HO-1, SOD, CAT, and GPx-1/2 were measured. HT074 pretreatment reduced NO production and increased the expression of HO-1, CAT, and GPx2 in LPS-induced RAW 264.7 cells. In GER-induced rats, HT074 significantly decreased esophageal lesions and increased the expression of HO-1, SOD, GPx-1/2, and Nrf2. HT074 did not affect gastric pH. These findings suggest that HT074 protects against GER-induced esophagitis by inhibiting NO production and enhancing antioxidant activity. Therefore, HT074 could be a promising therapeutic agent for GER disease.
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- 2024
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217. LC-QTOF/MS-Based Profiling of the Phytochemicals in Ice Plant (Mesembryanthemum crystallinum) and Their Bioactivities
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Mira Oh, Ah-Ram Han, Jaeyoun Lee, Sang Yoon Choi, Jae Woong Choi, Nho-Eul Song, Hee-Do Hong, Young Kyoung Rhee, and Chang-Won Cho
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phytochemicals ,anti-inflammatory ,plant extracts ,molecular network ,bioactive compounds ,Chemical technology ,TP1-1185 - Abstract
Recent assessments of the correlations between food and medicine underscore the importance of functional foods in disease prevention and management. Functional foods offer health benefits beyond basic nutrition, with fresh fruits and vegetables being particularly prominent because of their rich polyphenol content. In this study, we elucidated the phytochemicals in ice plant (Mesembryanthemum crystallinum), a globally consumed vegetable, using an LC-QTOF/MS-based untargeted detection method. The phytochemicals were clustered based on their structural similarity using molecular networking and annotated using the in silico tool for network annotation propagation. To identify the bioactive compounds, eight compounds were isolated from ice plant extracts. These compounds were identified using extensive spectroscopic methods, including 1H and 13C nuclear magnetic resonance (NMR) spectroscopy. Additionally, we evaluated the antioxidant and anti-inflammatory activities of all the isolates. Among the tested compounds, three showed antioxidant activity and all eight showed anti-inflammatory activity, demonstrating the potential of ice plant as a functional food.
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- 2024
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218. ALMA Survey of Orion Planck Galactic Cold Clumps (ALMASOP): Detection of extremely high density compact structure of prestellar cores and multiple substructures within
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Sahu, Dipen, Liu, Sheng-Yuan, Liu, Tie, Evans II, Neal J., Hirano, Naomi, Tatematsu, Ken'ichi, Lee, Chin-Fei, Kim, Kee-Tae, Dutta, Somnath, Alina, Dana, Bronfman, Leonardo, Cunningham, Maria, Eden, David J., Garay, Guido, Goldsmith, Paul F., He, Jinhua, Hsu, Shih-Ying, Jhan, Kai-Syun, Johnstone, Doug, Juvela, Mika, Kim, Gwanjeong, Kuan, Yi-Jehng, Kwon, Woojin, Lee, Chang Won, Lee, Jeong-Eun, Li, Di, Li, Pak Shing, Li, Shanghuo, Luo, Qiu-Yi, Montillaud, Julien, Moraghan, Anthony, Pelkonen, Veli-Matti, Qin, Sheng-Li, Ristorcelli, Isabelle, Sanhueza, Patricio, Shang, Hsien, Shen, Zhi-Qiang, Soam, Archana, Wu, Yuefang, Zhang, Qizhou, and Zhou, Jianjun
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Astrophysics - Astrophysics of Galaxies - Abstract
Prestellar cores are self-gravitating dense and cold structures within molecular clouds where future stars are born. They are expected, at the stage of transitioning to the protostellar phase, to harbor centrally concentrated dense (sub)structures that will seed the formation of a new star or the binary/multiple stellar systems. Characterizing this critical stage of evolution is key to our understanding of star formation. In this work, we report the detection of high density (sub)structures on the thousand-au scale in a sample of dense prestellar cores. Through our recent ALMA observations towards the Orion molecular cloud, we have found five extremely dense prestellar cores, which have centrally concentrated regions $\sim$ 2000 au in size, and several $10^7$ $cm^{-3}$ in average density. Masses of these centrally dense regions are in the range of 0.30 to 6.89 M$_\odot$. {\it For the first time}, our higher resolution observations (0.8$'' \sim $ 320 au) further reveal that one of the cores shows clear signatures of fragmentation; such individual substructures/fragments have sizes of 800 -1700 au, masses of 0.08 to 0.84 M$_\odot$, densities of $2 - 8\times 10^7$ $cm^{-3}$ and separations of $\sim 1200$ au. The substructures are massive enough ($\gtrsim 0.1~M_\odot$) to form young stellar objects and are likely examples of the earliest stage of stellar embryos which can lead to widely ($\sim$ 1200 au) separated multiple systems., Comment: Published in The Astrophysical Journal Letters (ApJL)
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- 2020
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219. Observations of magnetic fields surrounding LkH$\alpha$ 101 taken by the BISTRO survey with JCMT-POL-2
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Ngoc, Nguyen Bich, Diep, Pham Ngoc, Parsons, Harriet, Pattle, Kate, Hoang, Thiem, Ward-Thompson, Derek, Tram, Le Ngoc, Hull, Charles L. H., Tahani, Mehrnoosh, Furuya, Ray, Bastien, Pierre, Qiu, Keping, Hasegawa, Tetsuo, Kwon, Woojin, Doi, Yasuo, Lai, Shih-Ping, Coude, Simon, Berry, David, Ching, Tao-Chung, Hwang, Jihye, Soam, Archana, Wang, Jia-Wei, Arzoumanian, Doris, Bourke, Tyler L., Byun, Do-Young, Chen, Huei-Ru Vivien, Chen, Zhiwei, Chen, Wen Ping, Chen, Mike, Cho, Jungyeon, Choi, Yunhee, Choi, Minho, Chrysostomou, Antonio, Chung, Eun Jung, Dai, Sophia, Di Francesco, James, Duan, Yan, Duan, Hao-Yuan, Eden, David, Eswaraiah, Chakali, Fanciullo, Lapo, Fiege, Jason, Fissel, Laura M., Franzmann, Erica, Friberg, Per, Friesen, Rachel, Fuller, Gary, Gledhill, Tim, Graves, Sarah, Greaves, Jane, Griffin, Matt, Gu, Qilao, Han, Ilseung, Hatchell, Jennifer, Hayashi, Saeko, Houde, Martin, Inoue, Tsuyoshi, Inutsuka, Shu-ichiro, Iwasaki, Kazunari, Jeong, Il-Gyo, Johnstone, Doug, Kang, Ji-hyun, Kang, Sung-ju, Kang, Miju, Kataoka, Akimasa, Kawabata, Koji, Kemper, Francisca, Kim, Kee-Tae, Kim, Jongsoo, Pyo, Tae-Soo, Qian, Lei, Rao, Ramprasad, Rawlings, Mark, Rawlings, Jonathan, Retter, Brendan, Richer, John, Rigby, Andrew, Sadavoy, Sarah, Saito, Hiro, Savini, Giorgio, Scaife, Anna, Seta, Masumichi, Kim, Gwanjeong, Kim, Shinyoung, Kim, Kyoung Hee, Kim, Mi-Ryang, Kirchschlager, Florian, Kirk, Jason, Kobayashi, Masato I. N., Koch, Patrick M., Konyves, Vera, Kusune, Takayoshi, Kwon, Jungmi, Lacaille, Kevin, Law, Chi-Yan, Lee, Sang-Sung, Lee, Yong-Hee, Lee, Chin-Fei, Lee, Jeong-Eun, Lee, Hyeseung, Lee, Chang Won, Li, Di, Li, Hua-bai, Li, Dalei, Liu, Hong-Li, Liu, Junhao, Liu, Tie, Liu, Sheng-Yuan, Lu, Xing, Lyo, A-Ran, Mairs, Steve, Matsumura, Masafumi, Matthews, Brenda, Moriarty-Schieven, Gerald, Nagata, Tetsuya, Nakamura, Fumitaka, Nakanishi, Hiroyuki, Ohashi, Nagayoshi, Onaka, Takashi, Park, Geumsook, Peretto, Nicolas, Shimajiri, Yoshito, Shinnaga, Hiroko, Tamura, Motohide, Tang, Ya-Wen, Tang, Xindi, Tomisaka, Kohji, Tsukamoto, Yusuke, Viti, Serena, Wang, Hongchi, Whitworth, Anthony, Xie, Jinjin, Yen, Hsi-Wei, Yoo, Hyunju, Yuan, Jinghua, Yun, Hyeong-Sik, Zenko, Tetsuya, Zhang, Yapeng, Zhang, Chuan-Peng, Zhang, Guoyin, Zhou, Jianjun, Zhu, Lei, de Looze, Ilse, Andre, Philippe, Dowell, C. Darren, Eyres, Stewart, Falle, Sam, Robitaille, Jean-Francois, and van Loo, Sven
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Astrophysics - Astrophysics of Galaxies ,Astrophysics - Solar and Stellar Astrophysics - Abstract
We report the first high spatial resolution measurement of magnetic fields surrounding LkH$\alpha$ 101, a part of the Auriga-California molecular cloud. The observations were taken with the POL-2 polarimeter on the James Clerk Maxwell Telescope within the framework of the B-fields In Star-forming Region Observations (BISTRO) survey. Observed polarization of thermal dust emission at 850 $\mu$m is found to be mostly associated with the red-shifted gas component of the cloud. The magnetic field displays a relatively complex morphology. Two variants of the Davis-Chandrasekhar-Fermi method, unsharp masking and structure function, are used to calculate the strength of magnetic fields in the plane of the sky, yielding a similar result of $B_{\rm POS}\sim 115$ $\mathrm{\mu}$G. The mass-to-magnetic-flux ratio in critical value units, $\lambda\sim0.3$, is the smallest among the values obtained for other regions surveyed by POL-2. This implies that the LkH$\alpha$ 101 region is sub-critical and the magnetic field is strong enough to prevent gravitational collapse. The inferred $\delta B/B_0\sim 0.3$ implies that the large scale component of the magnetic field dominates the turbulent one. The variation of the polarization fraction with total emission intensity can be fitted by a power-law with an index of $\alpha=0.82\pm0.03$, which lies in the range previously reported for molecular clouds. We find that the polarization fraction decreases rapidly with proximity to the only early B star (LkH$\alpha$ 101) in the region. The magnetic field tangling and the joint effect of grain alignment and rotational disruption by radiative torques are potential of explaining such a decreasing trend., Comment: 25 pages, 19 figures, Accepted for publication in The Astrophysical Journal
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- 2020
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220. Human Care Assist System for Mitigating Motion Sickness Based on Enhancement of Situational Awareness in Autonomous Driving.
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Kihee Park, Yeong-Hun Park, and Chang Won Lee
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- 2023
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221. Machine learning-based classification and risk factor analysis of frailty in Korean community-dwelling older adults.
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Heeeun Jung, Miji Kim, Chang Won Won, Jinwook Kim, and Kyung-Ryoul Mun
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- 2023
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222. ProPanDL: A Modular Architecture for Uncertainty-Aware Panoptic Segmentation.
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Jacob Deery, Chang Won Lee, and Steven L. Waslander
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- 2023
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223. Density physics-informed neural networks reveal sources of cell heterogeneity in signal transduction
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Jo, Hyeontae, Hong, Hyukpyo, Hwang, Hyung Ju, Chang, Won, and Kim, Jae Kyoung
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- 2024
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224. Controlling dendrite growth and side reactions in anode-free Zn-ion aqueous batteries with PMMA:Zn coated electrode
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Jeong, Dae Yeop, Chang, Won Jun, Jang, Suhee, Kim, Minjoo, Kim, Yelim, Kim, Beomju, and Park, Won Il
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- 2024
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225. Experimental study on flow boiling CHF in annulus channel under heaving conditions using simulant fluid R134a targeting nuclear reactor applications
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Yoo, Jin-Seong, Lee, Chang Won, Hong, Heepyo, Ko, Hyukjae, Ku, Ja Hyun, Kim, Geon-Woo, Park, Goon-Cherl, and Cho, Hyoung Kyu
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- 2024
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226. Clinical effect on major trauma patients during simultaneous or overlapping presentations at an urban level I trauma center in Korea
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Park, Chang Won, Nho, Woo Young, Kim, Tae Kwon, Cho, Sung Hoon, Ahn, Jae Yun, and Seo, Kang Suk
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- 2024
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227. Improved charge transport kinetics in PbBi2Nb2O9 photocatalysts: Comparative time-resolved recombination study with N-doped TiO2
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Chae, Weon-Sik, Ahn, Chang Won, Hong, Kyong-Soo, Yoon, Jang-Hee, Bae, Jong-Seong, Kim, Jong Pil, Lee, Jaeyoung, Yang, Won-Geun, Borse, Pramod H., and Kim, Hyun Gyu
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- 2024
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228. The influence of different hinge position on PTS during HTO: comparison between open-wedge and closed-wedge HTO
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Moon, Dong-Kyu, Seo, Min-Seok, Kim, Chang-Won, Cho, Seong-Hee, Nam, Dae-Cheol, Byun, June-Ho, and Hwang, Sun-Chul
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- 2023
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229. Conical Horn Antenna with High Gain and Circular Polarization for Sub-mm-Wave/Terahertz
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Nguyen, Thinh Tien, Kim, Dong Ho, and Jung, Chang Won
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- 2023
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230. Associations between Maternal sFlt-1/PlGF Ratio and Perinatal and Neonatal Outcomes in Newborns Born to Mothers with Preeclampsia
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Hyo Ju Yang, Soo Yeon Lim, Hyun Soo Kim, Chang Won Choi, and Young Hwa Jung
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sflt-1/plgf ratio ,pre-eclampsia ,premature ,infant ,morbidity ,Pediatrics ,RJ1-570 - Abstract
Purpose The ratio of soluble fms-like tyrosine kinase 1 (sFlt-1) to placental growth factor (PlGF) is considered a predictive marker of preeclampsia. However, the relationship between the sFlt-1/PlGF ratio and perinatal and neonatal outcomes remains unknown. This study aimed to determine the associations of the sFlt-1/PlGF ratio with perinatal and neonatal outcomes in newborns born to mothers with preeclampsia. Methods This retrospective cohort study reviewed singleton neonates born to mothers with preeclampsia who underwent testing for the sFlt-1/PlGF ratio. We investigated the relationship between maternal sFlt-1/PlGF ratios and gestational age (GA), birth weight (Bwt), Bwt z-score, morbidities, and mortality of neonates born to mothers tested for the sFlt-1/PlGF ratio. Maternal sFlt-1/PlGF ratios examined within 30 days before delivery were used for analysis. Neonatal morbidities and mortality were investigated only in preterm infants born earlier than 32 weeks GA. Results A total of 225 neonates were included, of which 163 (72.4%) were preterm infants. GA (R=– 0.577, p
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- 2023
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231. Transparent and Flexible Patch Antenna Using MMF for Conformal WiFi-6E Applications
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Tien Dat Nguyen, Yongkeun Lee, and Chang Won Jung
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wi-fi 6e ,metal mesh film (mmf) ,transparent antenna ,flexible application ,conformal antenna ,Electrical engineering. Electronics. Nuclear engineering ,TK1-9971 ,Electricity and magnetism ,QC501-766 - Abstract
In this paper, a patch antenna with compact, flexible, and transparent properties is presented to support Wi-Fi 6E (2.4 GHz/6 GHz) applications. This antenna design was formulated based on a transparent metal mesh film (MMF), for which the average optical transparency (OTav) is 69% and the sheet resistance (Rs) is 0.1Ω/sq. The measurement results on frequency bands of 2.4–2.51 GHz and 5.87–7.04 GHz show that the average gain exceeds 5.4 dBi and 6.3 dBi with corresponding radiation efficiency rates as high as 67.8% and 70%. In addition, for the purpose of integration into aesthetic devices for smart home applications, the antenna conformed to foam and a lamp. All research outcomes here indicate that the proposed antenna maintains a directional radiation pattern, as well as transparency and flexibility, making it a potential candidate for transparent Internet of Things (IoT) applications.
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- 2023
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232. Intervention for Chest Trauma and Large Vessel Injury
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Hojun Lee, Hoon Kwon, Chang Won Kim, and Lee Hwangbo
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trauma ,embolotherapy ,endovascular stent grafting ,Medical physics. Medical radiology. Nuclear medicine ,R895-920 - Abstract
Trauma is an injury to the body that involves multiple anatomical and pathophysiological changes caused by forces acting from outside the body. The number of patients with trauma is increasing as our society becomes more sophisticated. The importance and demand of traumatology are growing due to the development and spread of treatment and diagnostic technologies. In particular, damage to the large blood vessels of the chest can be life-threatening, and the sequelae are often severe; therefore, diagnostic and therapeutic methods are becoming increasingly important. Trauma to nonaortic vessels of the thorax and aorta results in varying degrees of physical damage depending on the mechanism of the accident and anatomical damage involved. The main damage is hemorrhage from non-aortic vessels of the thorax and aorta, accompanied by hemodynamic instability and coagulation disorders, which can be life-threatening. Immediate diagnosis and rapid therapeutic access can often improve the prognosis. The treatment of trauma can be surgical or interventional, depending on the patient’s condition. Among them, interventional procedures are increasingly gaining popularity owing to their convenience, rapidity, and high therapeutic effectiveness, with increasing use in more trauma centers worldwide. Typical interventional procedures for patients with thoracic trauma include embolization for non-aortic injuries and thoracic endovascular aortic repair for aortic injuries. These procedures have many advantages over surgical treatments, such as fewer internal or surgical side effects, and can be performed more quickly than surgical procedures, contributing to improved outcomes for patients with trauma.
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- 2023
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233. Physical activity and osteosarcopenia in Korean adults aged 65 years and older: a national cross-sectional study using the KNHANES data
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Byung Chan Lee, Kang Hee Cho, and Chang-Won Moon
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Osteoporosis ,Sarcopenia ,Osteosarcopenia ,Exercise ,Strengthening exercise ,Cross-sectional study ,Geriatrics ,RC952-954.6 - Abstract
Abstract Background Osteosarcopenia is a syndrome characterized by the co-existence of osteoporosis and sarcopenia. This study aimed to examine the relationship between various types of physical activity and osteosarcopenia in community-dwelling Korean adults aged 65 years or older. Methods This cross-sectional study used raw data from the fourth and fifth editions of the Korean National Health and Nutritional Survey Examination, conducted from 2008 to 2011. The researchers exclusively recruited participants aged 65 years or older for the study. These participants were categorized into four distinct groups based on their clinical factors, namely individuals without osteoporosis or sarcopenia, those with osteoporosis alone, those with sarcopenia alone, and individuals with osteosarcopenia. The International Physical Activity Short-Form was used to calculate the weekly time spent walking, moderate-intensity aerobic physical activity, and vigorous aerobic physical activity. Number of days in performing strengthening or stretching exercises were also surveyed. We used logistic regression analyses to examine the association between various physical activities and occurrence of osteosarcopenia. Results A total of 1,342 participants (639 men and 703 women) were included in the analysis. No significant difference was observed in the amount and level of aerobic physical activity between the groups. The odds ratios below were based on participants without osteoporosis or sarcopenia as the reference category. The un-adjusted odds ratio of participants who performed stretching (male, 0.179, 95% CI 0.078–0.412; female 0.430, 95% CI 0.217–0.853) and strengthening exercises (male, 0.143, 95% CI 0.051–0.402; female, 0.044, 95% CI 0.006–0.342) at least twice per week was significantly lower in participants with osteosarcopenia compared to those without. In the adjusted analysis (adjusted by age, body mass index, house income, educational level, smoking habits, drinking status, and protein intake), only female patients in the osteosarcopenia group had a significantly lower adjusted odds ratio for performing strengthening exercise compared to female participants without osteoporosis or sarcopenia (0.062, 95% CI 0.007–0.538). Conclusions After adjusting for confounding factors and protein intake, women aged 65 years and older who suffered osteosarcopenia had considerably lower odds ratio of performing strengthening exercises.
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- 2023
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234. Mitochondrial aldehyde dehydrogenase-2 coordinates the hydrogen sulfide - AMPK axis to attenuate high glucose-induced pancreatic β-cell dysfunction by glutathione antioxidant system
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Udayakumar Karunakaran, Suma Elumalai, Seung Min Chung, Kathrin Maedler, Kyu Chang Won, and Jun Sung Moon
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Pancreatic β-cells ,Oxidative stress ,Glutathione ,Hydrogen sulfide ,Glucotoxicity ,CDK5/AMPK pathway ,Medicine (General) ,R5-920 ,Biology (General) ,QH301-705.5 - Abstract
Progression of β-cell loss in diabetes mellitus is significantly influenced by persistent hyperglycemia. At the cellular level, a number of signaling cascades affect the expression of apoptotic genes, ultimately resulting in β-cell failure; these cascades have not been elucidated. Mitochondrial aldehyde dehydrogenase-2 (ALDH2) plays a central role in the detoxification of reactive aldehydes generated from endogenous and exogenous sources and protects against mitochondrial deterioration in cells. Here we report that under diabetogenic conditions, ALDH2 is strongly inactivated in β-cells through CDK5-dependent glutathione antioxidant imbalance by glucose-6-phosphate dehydrogenase (G6PD) degradation. Intriguingly, CDK5 inhibition strengthens mitochondrial antioxidant defense through ALDH2 activation. Mitochondrial ALDH2 activation selectively preserves β-cells against high-glucose-induced dysfunction by activating AMPK and Hydrogen Sulfide (H2S) signaling. This is associated with the stabilization and enhancement of the activity of G6PD by SIRT2, a cytoplasmic NAD+-dependent deacetylase, and is thereby linked to an elevation in the GSH/GSSG ratio, which leads to the inhibition of mitochondrial dysfunction under high-glucose conditions. Furthermore, treatment with NaHS, an H2S donor, selectively preserves β-cell function by promoting ALDH2 activity, leading to the inhibition of lipid peroxidation by high-glucose concentrations. Collectively, our results provide the first direct evidence that ALDH2 activation enhances H2S-AMPK-G6PD signaling, leading to improved β-cell function and survival under high-glucose conditions via the glutathione redox balance.
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- 2024
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235. Direct Observational Evidence of Multi-epoch Massive Star Formation in G24.47+0.49
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Anindya Saha, Anandmayee Tej, Hong-Li Liu, Tie Liu, Guido Garay, Paul F. Goldsmith, Chang Won Lee, Jinhua He, Mika Juvela, Leonardo Bronfman, Tapas Baug, Enrique Vázquez-Semadeni, Patricio Sanhueza, Shanghuo Li, James O. Chibueze, N. K. Bhadari, Lokesh K. Dewangan, Swagat Ranjan Das, Feng-Wei Xu, Namitha Issac, Jihye Hwang, and L. Viktor Tóth
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Interstellar medium ,Star formation ,Star forming regions ,Astrophysics ,QB460-466 - Abstract
Using new continuum and molecular line data from the Atacama Large Millimeter/submillimeter Array Three-millimeter Observations of Massive Star-forming Regions (ATOMS) survey and archival Very Large Array, 4.86 GHz data, we present direct observational evidence of hierarchical triggering relating three epochs of massive star formation in a ringlike H ii region, G24.47+0.49. We find from radio flux analysis that it is excited by a massive star(s) of spectral type O8.5V–O8V from the first epoch of star formation. The swept-up ionized ring structure shows evidence of secondary collapse, and within this ring, a burst of massive star formation is observed in different evolutionary phases, which constitutes the second epoch. ATOMS spectral line (e.g., HCO ^+ (1–0)) observations reveal an outer concentric molecular gas ring expanding at a velocity of ∼9 km s ^−1 , constituting the direct and unambiguous detection of an expanding molecular ring. It harbors twelve dense molecular cores with surface mass density greater than 0.05 g cm ^−2 , a threshold typical of massive star formation. Half of them are found to be subvirial and thus in gravitational collapse making them the third epoch of potential massive star-forming sites.
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- 2024
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236. Efficacy of commercial recombinant HVT vaccines against a North American clade 2.3.4.4b H5N1 highly pathogenic avian influenza virus in chickens.
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Jiho Lee, Chang-Won Lee, David L Suarez, Scott A Lee, Taejoong Kim, and Erica Spackman
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Medicine ,Science - Abstract
The outbreak of clade 2.3.4.4b H5 highly pathogenic avian influenza (HPAI) in North America that started in 2021 has increased interest in applying vaccination as a strategy to help control and prevent the disease in poultry. Two commercially available vaccines based on the recombinant herpes virus of turkeys (rHVT) vector were tested against a recent North American clade 2.3.4.4b H5 HPAI virus isolate: A/turkey/Indiana/22-003707-003/2022 H5N1 in specific pathogen free white leghorn (WL) chickens and commercial broiler chickens. One rHVT-H5 vaccine encodes a hemagglutinin (HA) gene designed by the computationally optimized broadly reactive antigen method (COBRA-HVT vaccine). The other encodes an HA gene of a clade 2.2 virus (2.2-HVT vaccine). There was 100% survival of both chicken types COBRA-HVT vaccinated groups and in the 2.2-HVT vaccinated groups there was 94.8% and 90% survival of the WL and broilers respectively. Compared to the 2.2-HVT vaccinated groups, WL in the COBRA-HVT vaccinated group shed significantly lower mean viral titers by the cloacal route and broilers shed significantly lower titers by the oropharyngeal route than broilers. Virus titers detected in oral and cloacal swabs were otherwise similar among both vaccine groups and chicken types. To assess antibody-based tests to identify birds that have been infected after vaccination (DIVA-VI), sera collected after the challenge were tested with enzyme-linked lectin assay-neuraminidase inhibition (ELLA-NI) for N1 neuraminidase antibody detection and by commercial ELISA for detection of antibodies to the NP protein. As early as 7 days post challenge (DPC) 100% of the chickens were positive by ELLA-NI. ELISA was less sensitive with a maximum of 75% positive at 10DPC in broilers vaccinated with 2.2-HVT. Both vaccines provided protection from challenge to both types of chickens and ELLA-NI was sensitive at identifying antibodies to the challenge virus therefore should be evaluated further for DIVA-VI.
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- 2024
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237. Diabetes Primes Neutrophils for Neutrophil Extracellular Trap Formation through Trained Immunity
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Sanjeeb Shrestha, Yu-Bin Lee, Hoyul Lee, Yeon-Kyung Choi, Bo-Yoon Park, Mi-Jin Kim, Young-Jin Youn, Sun-Hwa Kim, Soo-Jung Jung, Dong-Keun Song, Hee Kyung Jin, Jae-Sung Bae, In-Kyu Lee, Jae-Han Jeon, and Chang-Won Hong
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Science - Abstract
Neutrophils are primed for neutrophil extracellular trap (NET) formation during diabetes, and excessive NET formation from primed neutrophils compromises wound healing in patients with diabetes. Here, we demonstrate that trained immunity mediates diabetes-induced NET priming in neutrophils. Under diabetic conditions, neutrophils exhibit robust metabolic reprogramming comprising enhanced glycolysis via the pentose phosphate pathway and fatty acid oxidation, which result in the accumulation of acetyl-coenzyme A. Adenosine 5′-triphosphate-citrate lyase-mediated accumulation of acetyl-coenzyme A and histone acetyltransferases further induce the acetylation of lysine residues on histone 3 (AcH3K9, AcH3K14, and AcH3K27) and histone 4 (AcH4K8). The pharmacological inhibition of adenosine 5′-triphosphate-citrate lyase and histone acetyltransferases completely inhibited high-glucose-induced NET priming. The trained immunity of neutrophils was further confirmed in neutrophils isolated from patients with diabetes. Our findings suggest that trained immunity mediates functional changes in neutrophils in diabetic environments, and targeting neutrophil-trained immunity may be a potential therapeutic target for controlling inflammatory complications of diabetes.
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- 2024
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238. On the Scarcity of Dense Cores (n > 105 cm−3) in High-latitude Planck Galactic Cold Clumps
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Fengwei Xu, Ke Wang, Tie Liu, David Eden, Xunchuan Liu, Mika Juvela, Jinhua He, Doug Johnstone, Paul Goldsmith, Guido Garay, Yuefang Wu, Archana Soam, Alessio Traficante, Isabelle Ristorcelli, Edith Falgarone, Huei-Ru Vivien Chen, Naomi Hirano, Yasuo Doi, Woojin Kwon, Glenn J. White, Anthony Whitworth, Patricio Sanhueza, Mark G. Rawlings, Dana Alina, Zhiyuan Ren, Chang Won Lee, Ken’ichi Tatematsu, Chuan-Peng Zhang, Jianjun Zhou, Shih-Ping Lai, Derek Ward-Thompson, Sheng-Yuan Liu, Qilao Gu, Eswaraiah Chakali, Lei Zhu, Diego Mardones, and L. Viktor Tóth
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Star formation ,Molecular clouds ,High latitude field ,Astrophysics ,QB460-466 - Abstract
High-latitude (∣ b ∣ > 30°) molecular clouds have virial parameters that exceed 1, but whether these clouds can form stars has not been studied systematically. Using JCMT SCUBA-2 archival data, we surveyed 70 fields that target high-latitude Planck Galactic cold clumps (HLPCs) to find dense cores with density of 10 ^5 –10 ^6 cm ^−3 and size of 1 × 10 ^21 cm ^−2 ). At an average rms of 15 mJy beam ^−1 , we detected Galactic dense cores in only one field, G6.04+36.77 (L183) while also identifying 12 extragalactic objects and two young stellar objects. Compared to the low-latitude clumps, dense cores are scarce in HLPCs. With synthetic observations, the densities of cores are constrained to be n _c ≲ 10 ^5 cm ^−3 should they exist in HLPCs. Low-latitude clumps, Taurus clumps, and HLPCs form a sequence where a higher virial parameter corresponds to a lower dense-core detection rate. If HLPCs were affected by the Local Bubble, the scarcity should favor turbulence-inhibited rather than supernova-driven star formation. Studies of the formation mechanism of the L183 molecular cloud are warranted.
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- 2024
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239. The ALMA-QUARKS Survey: Detection of Two Extremely Dense Substructures in a Massive Prestellar Core
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Xiaofeng Mai, Tie Liu, Xunchuan Liu, Lei Zhu, Guido Garay, Paul F. Goldsmith, Mika Juvela, Hongli Liu, Emma Mannfors, Anandmayee Tej, Patricio Sanhueza, Shanghuo Li, Fengwei Xu, Enrique Vazquez Semadeni, Wenyu Jiao, Yaping Peng, T. Baug, Aiyuan Yang, Lokesh Dewangan, Leonardo Bronfman, Gilberto C. Gómez, Aina Palau, Chang Won Lee, Sheng-Li Qin, Ken’ichi Tatematsu, James O. Chibueze, Dongting Yang, Xing Lu, Qiuyi Luo, Qilao Gu, Namitha Issac, Suinan Zhang, Pak-Shing Li, Bo Zhang, and L. Viktor Tóth
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Star formation ,Star forming regions ,Dark interstellar clouds ,Interstellar medium ,Astrophysics ,QB460-466 - Abstract
Only a handful of massive starless core candidates have been discovered so far, but none of them have been fully confirmed. Within the MM1 clump in the filamentary infrared dark cloud G34.43+0.24 that was covered by the Atacama Large Millimeter/submillimeter Array (ALMA) ATOMS survey at Band 3 (∼2″, 6000 au) and the ALMA-QUARKS survey at Band 6 (∼0.″3, 900 au), two prestellar core candidates MM1-C and E1 with masses of 71 and 20 M _⊙ and radii of 2100–4400 au were discovered. The two cores show no obvious sign of star formation activities. In particular, MM1-C is a very promising massive prestellar core candidate with a total gas mass of 71 M _⊙ . Within MM1-C, we detected two extremely dense substructures, C1 and C2, as characterized by their high densities of ${n}_{{{\rm{H}}}_{2}}\sim {10}^{8\mbox{--}9}\,{\mathrm{cm}}^{-3}$ . Moreover, evidence of further fragmentation in C2 was also revealed. We have detected the primordial fragmentation in the earliest stage of massive star formation, and we speculate that MM1-C would be the birthplace of a massive multiple system. However, we cannot fully rule out the possibility that the massive prestellar core MM1-C will just form a cluster of low-mass stars if it undergoes further fragmentation.
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- 2024
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240. JCMT POL-2 and BISTRO Survey observations of magnetic fields in the L1689 molecular cloud
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Pattle, Kate, Lai, Shih-Ping, Di Francesco, James, Sadavoy, Sarah, Ward-Thompson, Derek, Johnstone, Doug, Hoang, Thiem, Arzoumanian, Doris, Bastien, Pierre, Bourke, Tyler L., Coudé, Simon, Doi, Yasuo, Eswaraiah, Chakali, Fanciullo, Lapo, Furuya, Ray S., Hwang, Jihye, Hull, Charles L. H., Kang, Jihyun, Kim, Kee-Tae, Kirchschlager, Florian, Kwon, Jungmi, Kwon, Woojin, Lee, Chang Won, Liu, Tie, Redman, Matt, Soam, Archana, Tahani, Mehrnoosh, Tamura, Motohide, and Tang, Xindi
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Astrophysics - Astrophysics of Galaxies - Abstract
We present 850$\mu$m polarization observations of the L1689 molecular cloud, part of the nearby Ophiuchus molecular cloud complex, taken with the POL-2 polarimeter on the James Clerk Maxwell Telescope (JCMT). We observe three regions of L1689: the clump L1689N which houses the IRAS 16293-2422 protostellar system, the starless clump SMM-16, and the starless core L1689B. We use the Davis-Chandrasekhar-Fermi method to estimate plane-of-sky field strengths of $366\pm 55$ $\mu$G in L1689N, $284\pm 34$ $\mu$G in SMM-16, and $72\pm 33$ $\mu$G in L1689B, for our fiducial value of dust opacity. These values indicate that all three regions are likely to be magnetically trans-critical with sub-Alfv\'{e}nic turbulence. In all three regions, the inferred mean magnetic field direction is approximately perpendicular to the local filament direction identified in $Herschel$ Space Telescope observations. The core-scale field morphologies for L1689N and L1689B are consistent with the cloud-scale field morphology measured by the $Planck$ Space Observatory, suggesting that material can flow freely from large to small scales for these sources. Based on these magnetic field measurements, we posit that accretion from the cloud onto L1689N and L1689B may be magnetically regulated. However, in SMM-16, the clump-scale field is nearly perpendicular to the field seen on cloud scales by $Planck$, suggesting that it may be unable to efficiently accrete further material from its surroundings., Comment: 29 pages, 9 figures, 4 tables. Accepted for publication in the Astrophysical Journal
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- 2020
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241. The JCMT BISTRO survey: alignment between outflows and magnetic fields in dense cores/clumps
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Yen, Hsi-Wei, Koch, Patrick M., Hull, Charles L. H., Ward-Thompson, Derek, Bastien, Pierre, Hasegawa, Tetsuo, Kwon, Woojin, Lai, Shih-Ping, Qiu, Keping, Ching, Tao-Chung, Chung, Eun Jung, Coude, Simon, Di Francesco, James, Diep, Pham Ngoc, Doi, Yasuo, Eswaraiah, Chakali, Falle, Sam, Fuller, Gary, Furuya, Ray S., Han, Ilseung, Hatchell, Jennifer, Houde, Martin, Inutsuka, Shu-ichiro, Johnstone, Doug, Kang, Ji-hyun, Kang, Miju, Kim, Kee-Tae, Kirchschlager, Florian, Kwon, Jungmi, Lee, Chang Won, Lee, Chin-Fei, Liu, Hong-Li, Liu, Tie, Lyo, A-Ran, Ohashi, Nagayoshi, Onaka, Takashi, Pattle, Kate, Sadavoy, Sarah, Saito, Hiro, Shinnaga, Hiroko, Soam, Archana, Tahani, Mehrnoosh, Tamura, Motohide, Tang, Ya-Wen, Tang, Xindi, and Zhang, Chuan-Peng
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Astrophysics - Astrophysics of Galaxies ,Astrophysics - Solar and Stellar Astrophysics - Abstract
We compare the directions of molecular outflows of 62 low-mass Class 0 and I protostars in nearby (<450 pc) star-forming regions with the mean orientations of the magnetic fields on 0.05-0.5 pc scales in the dense cores/clumps where they are embedded. The magnetic field orientations were measured using the JCMT POL-2 data taken by the BISTRO-1 survey and from the archive. The outflow directions were observed with interferometers in the literature. The observed distribution of the angles between the outflows and the magnetic fields peaks between 15 and 35 degrees. After considering projection effects, our results could suggest that the outflows tend to be misaligned with the magnetic fields by 50+/-15 degrees in three-dimensional space and are less likely (but not ruled out) randomly oriented with respect to the magnetic fields. There is no correlation between the misalignment and the bolometric temperatures in our sample. In several sources, the small-scale (1000-3000 au) magnetic fields is more misaligned with the outflows than their large-scale magnetic fields, suggesting that the small-scale magnetic field has been twisted by the dynamics. In comparison with turbulent MHD simulations of core formation, our observational results are more consistent with models in which the energy densities in the magnetic field and the turbulence of the gas are comparable. Our results also suggest that the misalignment alone cannot sufficiently reduce the efficiency of magnetic braking to enable formation of the observed number of large Keplerian disks with sizes larger than 30-50 au., Comment: 27 pages, 14 figures, Accepted by ApJ
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- 2020
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242. ALMA Survey of Orion Planck Galactic Cold Clumps (ALMASOP) II. Survey overview: a first look at 1.3 mm continuum maps and molecular outflows
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Dutta, Somnath, Lee, Chin-Fei, Liu, Tie, Hirano, Naomi, Liu, Sheng-Yuan, Tatematsu, Kenichi, Kim, Kee-Tae, Shang, Hsien, Sahu, Dipen, Kim, Gwanjeong, Moraghan, Anthony, Jhan, Kai-Syun, Hsu, Shih-Ying, Evans, Neal J., Johnstone, Doug, Ward-Thompson, Derek, Kuan, Yi-Jehng, Lee, Chang Won, Lee, Jeong-Eun, Traficante, Alessio, Juvela, Mika, Vastel, Charlotte, Zhang, Qizhou, Sanhueza, Patricio, Soam, Archana, Kwon, Woojin, Bronfman, Leonardo, Eden, David, Goldsmith, Paul F., He, Jinhua, Wu, Yuefang, Pelkonen, Veli-Matti, Qin, Sheng-Li, Li, Shanghuo, and Li, Di
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Astrophysics - Astrophysics of Galaxies ,Astrophysics - Solar and Stellar Astrophysics - Abstract
Planck Galactic Cold Clumps (PGCCs) are contemplated to be the ideal targets to probe the early phases of star formation. We have conducted a survey of 72 young dense cores inside PGCCs in the Orion complex with the Atacama Large Millimeter/submillimeter Array (ALMA) at 1.3\,mm (band 6) using three different configurations (resolutions $\sim$ 0$\farcs$35, 1$\farcs$0, and 7$\farcs$0) to statistically investigate their evolutionary stages and sub-structures. We have obtained images of the 1.3\,mm continuum and molecular line emission ($^{12}$CO, and SiO) at an angular resolution of $\sim$ 0$\farcs$35 ($\sim$ 140\,au) with the combined arrays. We find 70 substructures within 48 detected dense cores with median dust-mass $\sim$ 0.093\,M$_{\sun}$ and deconvolved size $\sim$ 0$\farcs$27. Dense substructures are clearly detected within the central 1000\,au of four candidate prestellar cores. The sizes and masses of the substructures in continuum emission are found to be significantly reduced with protostellar evolution from Class\,0 to Class\,I. We also study the evolutionary change in the outflow characteristics through the course of protostellar mass accretion. A total of 37 sources exhibit CO outflows, and 20 ($>$50\%) show high-velocity jets in SiO. The CO velocity-extents ($\Delta$Vs) span from 4 to 110 km/s with outflow cavity opening angle width at 400\,au ranging from $[\Theta_{obs}]_{400}$ $\sim$ 0$\farcs$6 to 3$\farcs$9, which corresponds to 33$\fdg$4$-$125$\fdg$7. For the majority of the outflow sources, the $\Delta$Vs show a positive correlation with $[\Theta_{obs}]_{400}$, suggesting that as protostars undergo gravitational collapse, the cavity opening of a protostellar outflow widens and the protostars possibly generate more energetic outflows., Comment: 43 pages, 25 figures (14 in the main text, 9 in the appendix), accepted for publication in the Astrophysical Journal Supplement Series (ApJS)
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- 2020
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243. OMC-1 dust polarisation in ALMA Band 7: Diagnosing grain alignment mechanisms in the vicinity of Orion Source I
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Pattle, Kate, Lai, Shih-Ping, Wright, Melvyn, Coudé, Simon, Plambeck, Richard, Hoang, Thiem, Tang, Ya-Wen, Bastien, Pierre, Eswaraiah, Chakali, Furuya, Ray, Hwang, Jihye, Inutsuka, Shu-ichiro, Kim, Kee-Tae, Kirchschlager, Florian, Kwon, Woojin, Lee, Chang Won, Liu, Sheng-Yuan, Lyo, Aran, Ohashi, Nagayoshi, Rawlings, Mark, Tahani, Mehrnoosh, Tamura, Motohide, Soam, Archana, Wang, Jia-Wei, and Ward-Thompson, Derek
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Astrophysics - Astrophysics of Galaxies - Abstract
We present ALMA Band 7 polarisation observations of the OMC-1 region of the Orion molecular cloud. We find that the polarisation pattern observed in the region is likely to have been significantly altered by the radiation field of the $>10^{4}$ L$_{\odot}$ high-mass protostar Orion Source I. In the protostar's optically thick disc, polarisation is likely to arise from dust self-scattering. In material to the south of Source I - previously identified as a region of 'anomalous' polarisation emission - we observe a polarisation geometry concentric around Source I. We demonstrate that Source I's extreme luminosity may be sufficient to make the radiative precession timescale shorter than the Larmor timescale for moderately large grains ($> 0.005-0.1\,\mu$m), causing them to precess around the radiation anisotropy vector (k-RATs) rather than the magnetic field direction (B-RATs). This requires relatively unobscured emission from Source I, supporting the hypothesis that emission in this region arises from the cavity wall of the Source I outflow. This is one of the first times that evidence for k-RAT alignment has been found outside of a protostellar disc or AGB star envelope. Alternatively, the grains may remain aligned by B-RATs and trace gas infall onto the Main Ridge. Elsewhere, we largely find the magnetic field geometry to be radial around the BN/KL explosion centre, consistent with previous observations. However, in the Main Ridge, the magnetic field geometry appears to remain consistent with the larger-scale magnetic field, perhaps indicative of the ability of the dense Ridge to resist disruption by the BN/KL explosion., Comment: 20 pages, 20 figures, 3 tables, accepted for publication in Monthly Notices of the Royal Astronomical Society (MNRAS)
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- 2020
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244. Computer Model Calibration with Time Series Data using Deep Learning and Quantile Regression
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Bhatnagar, Saumya, Chang, Won, and Wang, Seonjin Kim Jiali
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Statistics - Machine Learning ,Computer Science - Machine Learning ,Statistics - Methodology - Abstract
Computer models play a key role in many scientific and engineering problems. One major source of uncertainty in computer model experiment is input parameter uncertainty. Computer model calibration is a formal statistical procedure to infer input parameters by combining information from model runs and observational data. The existing standard calibration framework suffers from inferential issues when the model output and observational data are high-dimensional dependent data such as large time series due to the difficulty in building an emulator and the non-identifiability between effects from input parameters and data-model discrepancy. To overcome these challenges we propose a new calibration framework based on a deep neural network (DNN) with long-short term memory layers that directly emulates the inverse relationship between the model output and input parameters. Adopting the 'learning with noise' idea we train our DNN model to filter out the effects from data model discrepancy on input parameter inference. We also formulate a new way to construct interval predictions for DNN using quantile regression to quantify the uncertainty in input parameter estimates. Through a simulation study and real data application with WRF-hydro model we show that our approach can yield accurate point estimates and well calibrated interval estimates for input parameters.
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- 2020
245. Revisiting the Magnetic Field of the L183 Starless Core
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Karoly, Janik, Soam, Archana, Andersson, B-G, Coudé, Simon, Bastien, Pierre, Vaillancourt, John E., and Lee, Chang Won
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Astrophysics - Solar and Stellar Astrophysics ,Astrophysics - Astrophysics of Galaxies - Abstract
We present observations of linear polarization from dust thermal emission at 850 $\mu m$ towards the starless cloud L183. These data were obtained at the James Clerk Maxwell Telescope (JCMT) using the Submillimetre Common-User Bolometer Array 2 (SCUBA-2) camera in conjunction with its polarimeter POL-2. Polarized dust emission traces the plane-of-sky magnetic field structure in the cloud, thus allowing us to investigate the role of magnetic fields in the formation and evolution of its starless core. To interpret these measurements, we first calculate the dust temperature and column density in L183 by fitting the spectral energy distribution obtained by combining data from the JCMT and the $\textit{Herschel}$ space observatory. We used the Davis-Chandrasekhar-Fermi technique to measure the magnetic field strength in five sub-regions of the cloud, and we find values ranging from $\sim120\pm18~\mu G$ to $\sim270\pm64~\mu G$ in agreement with previous studies. Combined with an average hydrogen column density ($N_{\text{H}_2}$) of $\sim 1.5 \times 10^{22} $cm$^{-2}$ in the cloud, we also find that all five sub-regions are magnetically subcritical. These results indicate that the magnetic field in L183 is sufficiently strong to oppose the gravitational collapse of the cloud., Comment: 14 pages, 9 figures, accepted for publication to ApJ
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- 2020
246. The JCMT BISTRO Survey: Magnetic Fields Associated with a Network of Filaments in NGC 1333
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Doi, Yasuo, Hasegawa, Tetsuo, Furuya, Ray S., Coudé, Simon, Hull, Charles L. H., Arzoumanian, Doris, Bastien, Pierre, Chen, Michael Chun-Yuan, di Francesco, James, Friesen, Rachel, Houde, Martin, Inutsuka, Shu-ichiro, Mairs, Steve, Matsumura, Masafumi, Onaka, Takashi, Sadavoy, Sarah, Shimajiri, Yoshito, Tahani, Mehrnoosh, Tomisaka, Kohji, Eswaraiah, Chakali, Koch, Patrick M., Pattle, Kate, Lee, Chang Won, Tamura, Motohide, Berry, David, Ching, Tao-Chung, Hwang, Jihye, Kwon, Woojin, Soam, Archana, Wang, Jia-Wei, Lai, Shih-Ping, Qiu, Keping, Ward-Thompson, Derek, Byun, Do-Young, Chen, Huei-Ru V., Chen, Wen Ping, Chen, Zhiwei, Cho, Jungyeon, Choi, Minho, Choi, Yunhee, Chrysostomou, Antonio, Chung, Eun Jung, Diep, Pham Ngoc, Duan, Hao-Yuan, Fanciullo, Lapo, Fiege, Jason, Franzmann, Erica, Friberg, Per, Fuller, Gary, Gledhill, Tim, Graves, Sarah F., Greaves, Jane S., Griffin, Matt J., Gu, Qilao, Han, Ilseung, Hatchell, Jennifer, Hayashi, Saeko S., Hoang, Thiem, Inoue, Tsuyoshi, Iwasaki, Kazunari, Jeong, Il-Gyo, Johnstone, Doug, Kanamori, Yoshihiro, Kang, Ji-hyun, Kang, Miju, Kang, Sung-Ju, Kataoka, Akimasa, Kawabata, Koji S., Kemper, Francisca, Kim, Gwanjeong, Kim, Jongsoo, Kim, Kee-Tae, Kim, Kyoung Hee, Kim, Mi-Ryang, Kim, Shinyoung, Kirk, Jason M., Kobayashi, Masato I. N., Konyves, Vera, Kusune, Takayoshi, Kwon, Jungmi, Lacaille, Kevin, Law, Chi-Yan, Lee, Chin-Fei, Lee, Hyeseung, Lee, Jeong-Eun, Lee, Sang-Sung, Lee, Yong-Hee, Li, Dalei, Li, Di, Li, Hua-Bai, Liu, Hong-Li, Liu, Junhao, Liu, Sheng-Yuan, Liu, Tie, de Looze, Ilse, Lyo, A-Ran, Matthews, Brenda C., Moriarty-Schieven, Gerald H., Nagata, Tetsuya, Nakamura, Fumitaka, Nakanishi, Hiroyuki, Ohashi, Nagayoshi, Park, Geumsook, Parsons, Harriet, Peretto, Nicolas, Pyo, Tae-Soo, Qian, Lei, Rao, Ramprasad, Rawlings, Mark G., Retter, Brendan, Richer, John, Rigby, Andrew, Saito, Hiro, Savini, Giorgio, Scaife, Anna M. M., Seta, Masumichi, Shinnaga, Hiroko, Tang, Ya-Wen, Tsukamoto, Yusuke, Viti, Serena, Wang, Hongchi, Whitworth, Anthony P., Yen, Hsi-Wei, Yoo, Hyunju, Yuan, Jinghua, Yun, Hyeong-Sik, Zenko, Tetsuya, Zhang, Chuan-Peng, Zhang, Guoyin, Zhang, Yapeng, Zhou, Jianjun, Zhu, Lei, André, Philippe, Dowell, C. Darren, Eyres, Stewart P. S., Falle, Sam, van Loo, Sven, and Robitaille, Jean-François
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Astrophysics - Astrophysics of Galaxies - Abstract
We present new observations of the active star-formation region NGC 1333 in the Perseus molecular cloud complex from the James Clerk Maxwell Telescope B-Fields In Star-forming Region Observations (BISTRO) survey with the POL-2 instrument. The BISTRO data cover the entire NGC 1333 complex (~1.5 pc x 2 pc) at 0.02 pc resolution and spatially resolve the polarized emission from individual filamentary structures for the first time. The inferred magnetic field structure is complex as a whole, with each individual filament aligned at different position angles relative to the local field orientation. We combine the BISTRO data with low- and high- resolution data derived from Planck and interferometers to study the multiscale magnetic field structure in this region. The magnetic field morphology drastically changes below a scale of ~1 pc and remains continuous from the scales of filaments (~0.1 pc) to that of protostellar envelopes (~0.005 pc or ~1000 au). Finally, we construct simple models in which we assume that the magnetic field is always perpendicular to the long axis of the filaments. We demonstrate that the observed variation of the relative orientation between the filament axes and the magnetic field angles are well reproduced by this model, taking into account the projection effects of the magnetic field and filaments relative to the plane of the sky. These projection effects may explain the apparent complexity of the magnetic field structure observed at the resolution of BISTRO data toward the filament network., Comment: 33 pages, 21 figures, accepted for publication in ApJ
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- 2020
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247. ALMA Survey of Orion Planck Galactic Cold Clumps (ALMASOP): I. Detection of New Hot Corinos with ACA
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Hsu, Shih-Ying, Liu, Sheng-Yuan, Liu, Tie, Sahu, Dipen, Hirano, Naomi, Lee, Chin-Fei, Tatematsu, Kenichi, Kim, Gwanjeong, Juvela, Mika, Sanhueza, Patricio, He, Jinhua, Johnstone, Doug, Qin, Sheng-Li, Bronfman, Leonardo J., Chen, Huei-Ru, Dutta, Somnath, Eden, David, Jhan, Kai-Syun, Kim, Kee-Tae, Kuan, Yi-Jehng, Kwon, Woojin, Lee, Chang Won, Lee, Jeong-Eun, Moraghan, Anthony, Rawlings, Mark, Shang, Hsien, Soam, Archana, Thompson, Mark, Traficante, Alessio, Wu, Yuefang, Yang, Yao-Lun, and Zhang, Qizhou
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Astrophysics - Solar and Stellar Astrophysics ,Astrophysics - Astrophysics of Galaxies - Abstract
We report the detection of four new hot corino sources, G211.47-19.27S, G208.68-19.20N1, G210.49-19.79W and G192.12-11.10 from a survey study of Planck Galactic Cold Clumps in the Orion Molecular Cloud Complex with the Atacama Compact Array (ACA). Three sources had been identified as low mass Class 0 protostars in the Herschel Orion Protostar Survey (HOPS). One source in the lambda Orionis region is firstly reported as a protostellar core. We have observed abundant complex organic molecules (COMs), primarily methanol but also other oxygen-bearing COMs (in G211.47-19.27S and G208.68-19.20N1) and the molecule of prebiotic interest NH2CHO (in G211.47-19.27S), signifying the presence of hot corinos. While our spatial resolution is not sufficient for resolving most of the molecular emission structure, the large linewidth and high rotational temperature of COMs suggest that they likely reside in the hotter and innermost region immediately surrounding the protostar. In G211.47-19.27S, the D/H ratio of methanol ([CH2DOH]/[CH3OH]) and the 12C/13C ratio of methanol ([CH3OH]/[13CH3OH]) are comparable to those of other hot corinos. Hydrocarbons and long carbon-chain molecules such as c-C3H2 and HCCCN are also detected in the four sources, likely tracing the outer and cooler molecular envelopes., Comment: 37 pages, 51 figures, to be published in ApJ
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- 2020
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248. Highly ordered lead-free double perovskite halides by design
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Ahn, Chang Won, Jo, Jae Hun, Kim, Jong Chan, Ullah, Hamid, Ryu, Sangkyun, Hwang, Younghun, Choi, Jin San, Lee, Jongmin, Lee, Sanghan, Jeen, Hyoungjeen, Shin, Young-Han, Jeong, Hu Young, Kim, Ill Won, and Kim, Tae Heon
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Condensed Matter - Materials Science ,Physics - Chemical Physics - Abstract
Lead-free double perovskite halides are emerging optoelectronic materials that are alternatives to lead-based perovskite halides. Recently, single-crystalline double perovskite halides were synthesized, and their intriguing functional properties were demonstrated. Despite such pioneering works, lead-free double perovskite halides with better crystallinity are still in demand for applications to novel optoelectronic devices. Here, we realized highly crystalline Cs2AgBiBr6 single crystals with a well-defined atomic ordering on the microscopic scale. We avoided the formation of Ag vacancies and the subsequent secondary Cs3Bi2Br9 by manipulating the initial chemical environments in hydrothermal synthesis. The suppression of Ag vacancies allows us to reduce the trap density in the as-grown crystals and to enhance the carrier mobility further. Our design strategy is applicable for fabricating other lead-free halide materials with high crystallinity.
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- 2020
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249. ATOMS: ALMA Three-millimeter Observations of Massive Star-forming regions -- I. Survey description and a first look at G9.62+0.19
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Liu, Tie, Evans, Neal J., Kim, Kee-Tae, Goldsmith, Paul F., Liu, Sheng-Yuan, Zhang, Qizhou, Tatematsu, Kenichi, Wang, Ke, Juvela, Mika, Bronfman, Leonardo, Cunningham, Maria. R., Garay, Guido, Hirota, Tomoya, Lee, Jeong-Eun, Kang, Sung-Ju, Li, Di, Li, Pak-Shing, Mardones, Diego, Qin, Sheng-Li, Ristorcelli, Isabelle, Tej, Anandmayee, Toth, L. Viktor, Wu, Jing-Wen, Wu, Yue-Fang, Yi, Hee-weon, Yun, Hyeong-Sik, Liu, Hong-Li, Peng, Ya-Ping, Li, Juan, Li, Shang-Huo, Lee, Chang-Won, Shen, Zhi-Qiang, Baug, Tapas, Wang, Jun-Zhi, Zhang, Yong, Issac, Namitha, Zhu, Feng-Yao, Luo, Qiu-Yi, Soam, Archana, Liu, Xun-Chuan, Xu, Feng-Wei, Wang, Yu, Zhang, Chao, and Ren, Zhiyuan
- Subjects
Astrophysics - Astrophysics of Galaxies ,Astrophysics - Solar and Stellar Astrophysics - Abstract
The "ATOMS," standing for {\it ALMA Three-millimeter Observations of Massive Star-forming regions}, survey has observed 146 active star forming regions with ALMA Band 3, aiming to systematically investigate the spatial distribution of various dense gas tracers in a large sample of Galactic massive clumps, to study the roles of stellar feedback in star formation, and to characterize filamentary structures inside massive clumps. In this work, the observations, data analysis, and example science of the "ATOMS" survey are presented, using a case study for the G9.62+0.19 complex. Toward this source, some transitions, commonly assumed to trace dense gas, including CS $J = 2-1$, HCO$^+$ $J = 1-0$ and HCN $J = 1-0$, are found to show extended gas emission in low density regions within the clump; less than 25\% of their emission is from dense cores. SO, CH$_3$OH, H$^{13}$CN and HC$_3$N show similar morphologies in their spatial distributions and reveal well the dense cores. Widespread narrow SiO emission is present (over $\sim$1 pc), which may be caused by slow shocks from large--scale colliding flows or H{\sc ii} regions. Stellar feedback from an expanding H{\sc ii} region has greatly reshaped the natal clump, significantly changed the spatial distribution of gas, and may also account for the sequential high-mass star formation in the G9.62+0.19 complex. The ATOMS survey data can be jointly analyzed with other survey data, e.g., "MALT90", "Orion B", "EMPIRE", "ALMA\_IMF", and "ALMAGAL", to deepen our understandings of "dense gas" star formation scaling relations and massive proto-cluster formation., Comment: published on MNRAS
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- 2020
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250. ATOMS: ALMA Three-millimeter Observations of Massive Star-forming regions -- II. Compact objects in ACA observations and star formation scaling relations
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Liu, Tie, Evans, Neal J., Kim, Kee-Tae, Goldsmith, Pail F., Liu, Sheng-Yuan, Zhang, Qizhou, Tatematsu, Kenichi, Wang, Ke, Juvela, Mika, Bronfman, Leonardo, Cunningham, Maria. R., Garay, Guido, Hirota, Tomoya, Lee, Jeong-Eun, Kang, Sung-Ju, Li, Di, Li, Pak-Shing, Mardones, Diego, Qin, Sheng-Li, Ristorcelli, Isabelle, Tej, Anandmayee, Toth, L. Viktor, Wu, Jing-Wen, Wu, Yue-Fang, Yi, Hee-weon, Yun, Hyeong-Sik, Liu, Hong-Li, Peng, Ya-Ping, Li, Juan, Li, Shang-Huo, Lee, Chang-Won, Shen, Zhi-Qiang, Baug, Tapas, Wang, Jun-Zhi, Zhang, Yong, Issac, Namitha, Zhu, Feng-Yao, Luo, Qiu-Yi, Liu, Xun-Chuan, Xu, Feng-Wei, Wang, Yu, Zhang, Chao, and Ren, Zhiyuan
- Subjects
Astrophysics - Astrophysics of Galaxies ,Astrophysics - Solar and Stellar Astrophysics - Abstract
We report studies of the relationships between the total bolometric luminosity ($L_{\rm bol}$ or $L_{\rm TIR}$) and the molecular line luminosities of $J=1-0$ transitions of H$^{13}$CN, H$^{13}$CO$^+$, HCN, and HCO$^+$ with data obtained from ACA observations in the "ATOMS" survey of 146 active Galactic star forming regions. The correlations between $L_{\rm bol}$ and molecular line luminosities $L'_{\rm mol}$ of the four transitions all appear to be approximately linear. Line emission of isotopologues shows as large scatters in $L_{\rm bol}$-$L'_{\rm mol}$ relations as their main line emission. The log($L_{\rm bol}$/$L'_{\rm mol}$) for different molecular line tracers have similar distributions. The $L_{\rm bol}$-to-$L'_{\rm mol}$ ratios do not change with galactocentric distances ($R_{\rm GC}$) and clump masses ($M_{\rm clump}$). The molecular line luminosity ratios (HCN-to-HCO$^+$, H$^{13}$CN-to-H$^{13}$CO$^+$, HCN-to-H$^{13}$CN and HCO$^+$-to-H$^{13}$CO$^+$) all appear constant against $L_{\rm bol}$, dust temperature ($T_{\rm d}$), $M_{\rm clump}$ and $R_{\rm GC}$. Our studies suggest that both the main lines and isotopologue lines are good tracers of the total masses of dense gas in Galactic molecular clumps. The large optical depths of main lines do not affect the interpretation of the slopes in star formation relations. We find that the mean star formation efficiency (SFE) of massive Galactic clumps in the "ATOMS" survey is reasonably consistent with other measures of the SFE for dense gas, even those using very different tracers or examining very different spatial scales., Comment: Published on MNRAS. The full tables are included in Tables.pdf or Tables.tex files, which can be downloaded from source files
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- 2020
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