811 results on '"Cheng, Seng"'
Search Results
202. Inhibition of glycogen biosynthesis via mTORC1 suppression as an adjunct therapy for Pompe disease
203. Increased Hepatic Insulin Action in Diet-Induced Obese Mice Following Inhibition of Glucosylceramide Synthase
204. Optical Signal Modulation of Semiconductor Soliton Device with Circular Ring Resonator
205. 90. Efficacy of Genz-529468-mediated inhibition of glucosylceramide synthase in a mouse model of Sandhoff disease
206. 91. Management of lysosomal glycosphingolipid levels in animal models of Gaucher and Fabry disease with enzyme and substrate reduction therapies
207. An Alternative Non-contact Planarization Technique by Utilizing the Electrokinetic Phenomenon
208. Low-frequency ultrasound increases non-viral gene transfer to the mouse lung
209. AAV8-mediated Gene Therapy Prevents Induced Biochemical Attacks of Acute Intermittent Porphyria and Improves Neuromotor Function
210. Nanometric material removal using electrokinetic phenomenon
211. Detection of CFTR transgene mRNA expression in respiratory epithelium isolated from the murine nasal cavity
212. Glycoengineered Acid α-Glucosidase With Improved Efficacy at Correcting the Metabolic Aberrations and Motor Function Deficits in a Mouse Model of Pompe Disease
213. A hypoxic inducible factor-1α hybrid enhances collateral development and reduces vascular leakage in diabetic rats
214. Pulmonary delivery of recombinant acid sphingomyelinase improves clearance of lysosomal sphingomyelin from the lungs of a murine model of Niemann–Pick disease
215. Optical Signal Modulation of Semiconductor Soliton Device with Circular Ring Resonator
216. Temporal Neuropathologic and Behavioral Phenotype of 6neo/6neoPompe Disease Mice
217. Ability of Adeno-Associated Virus Serotype 8-Mediated Hepatic Expression of Acid α-Glucosidase to Correct the Biochemical and Motor Function Deficits of Presymptomatic and Symptomatic Pompe Mice
218. Delivery of AAV-IGF-1 to the CNS Extends Survival in ALS Mice Through Modification of Aberrant Glial Cell Activity
219. CpG-free plasmids confer reduced inflammation and sustained pulmonary gene expression
220. Intraventricular Enzyme Replacement Improves Disease Phenotypes in a Mouse Model of Late Infantile Neuronal Ceroid Lipofuscinosis
221. Hypoxia-inducible factor 1 mediates hypoxia-induced cardiomyocyte lipid accumulation by reducing the DNA binding activity of peroxisome proliferator-activated receptor α/retinoid X receptor
222. Timing of Therapeutic Intervention Determines Functional and Survival Outcomes in a Mouse Model of Late Infantile Batten Disease
223. A specific and potent inhibitor of glucosylceramide synthase for substrate inhibition therapy of Gaucher disease
224. Correction of the Biochemical and Functional Deficits in Fabry Mice Following AAV8–mediated Hepatic Expression of α-galactosidase A
225. Identification of transfected cell types following non‐viral gene transfer to the murine lung
226. Optimizing Aerosol Gene Delivery and Expression in the Ovine Lung
227. Hyaluronidase increases the biodistribution of acid α-1,4 glucosidase in the muscle of Pompe disease mice: An approach to enhance the efficacy of enzyme replacement therapy
228. Cell and Gene-Based Therapies for the Lysosomal Storage Diseases
229. Inefficient cationic lipid-mediated siRNA and antisense oligonucleotide transfer to airway epithelial cells in vivo
230. Intracranial Delivery of CLN2 Reduces Brain Pathology in a Mouse Model of Classical Late Infantile Neuronal Ceroid Lipofuscinosis
231. 475. SeV-Mediated Gene Transfer after Three Re-Administrations in Mice and Sheep
232. 2. Identification of Different Modes of Viral Transport in the Non-Human Primate Brain after Convection-Enhanced Delivery of AAV Serotype Vectors
233. 696. Development of Lipid/Peptide (Lip/Tide) Vectors for Respiratory Gene Transfer
234. 786. Development of Zero-CpG Plasmids with Reduced Inflammatory Responses Following Delivery of Lipid/pDNA Complexes to the Mouse Lung
235. 226. Effective Gene Therapy in an Authentic Mouse Model of Tay-Sachs Related Diseases
236. 218. Gene Therapy and Enzyme Replacement in a Mouse Model of Late Infantile Neuronal Ceroid Lipofuscinosis
237. 217. Comparison of Hepatic Vein and Peripheral Vein Delivery of an AAV2/8 Vector Encoding Human a-Galactosidase A to Rhesus Macaques
238. 893. Second Generation Gene Therapy Vector for Classical Late Infantile Neuronal Ceroid Lipofuscinosis
239. 1062. Intracerebellar Injection of AAV-IGF-1 Improves Motor Function and Extends Survival in a Mouse Model of Amyotrophic Lateral Sclerosis
240. 695. Low-Frequency Ultrasound Increases Non- Viral Lung Gene Transfer
241. AAV8-Mediated Hepatic Expression of Acid Sphingomyelinase Corrects the Metabolic Defect in the Visceral Organs of a Mouse Model of Niemann–Pick Disease
242. Carbohydrate-remodelled acid α-glucosidase with higher affinity for the cation-independent mannose 6-phosphate receptor demonstrates improved delivery to muscles of Pompe mice
243. Adenovirus-Mediated Expression of β-Adrenergic Receptor Kinase C-Terminus Reduces Intimal Hyperplasia and Luminal Stenosis of Arteriovenous Polytetrafluoroethylene Grafts in Pigs
244. Expression of constitutively stable hybrid hypoxia-inducible factor-1α protects cultured rat cardiomyocytes against simulated ischemia-reperfusion injury
245. Reducing the immunostimulatory activity of CpG-containing plasmid DNA vectors for non-viral gene therapy
246. Conjugation of Mannose 6-Phosphate-containing Oligosaccharides to Acid α-Glucosidase Improves the Clearance of Glycogen in Pompe Mice
247. Expression of angiopoietins in renal epithelial and clear cell carcinoma cells: regulation by hypoxia and participation in angiogenesis
248. Effect of Baseline or Changes in Adrenergic Activity on Clinical Outcomes in the β-Blocker Evaluation of Survival Trial
249. Catheter‐mediated delivery of adenoviral vectors expressing β‐adrenergic receptor kinase C‐terminus inhibits intimal hyperplasia and luminal stenosis in rabbit iliac arteries
250. Fas Ligand Gene Therapy for Vascular Intimal Hyperplasia
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