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1,876 results on '"Day, Nicholas P. J."'

201. Associations Between Restrictive Fluid Management and Renal Function and Tissue Perfusion in Adults With Severe Falciparum Malaria: A Prospective Observational Study

Author

Ishioka, Haruhiko, primary, Plewes, Katherine, additional, Pattnaik, Rajyabardhan, additional, Kingston, Hugh W F, additional, Leopold, Stije J, additional, Herdman, M Trent, additional, Mahanta, Kishore, additional, Mohanty, Anita, additional, Dey, Chandan, additional, Alam, Shamsul, additional, Srinamon, Ketsanee, additional, Mohanty, Akshaya, additional, Maude, Richard J, additional, White, Nicholas J, additional, Day, Nicholas P J, additional, Hossain, Md Amir, additional, Faiz, Md Abul, additional, Charunwatthana, Prakaykaew, additional, Mohanty, Sanjib, additional, Ghose, Aniruddha, additional, and Dondorp, Arjen M, additional

Published
2019
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203. Impact of 13-Valent Pneumococcal Conjugate Vaccine on Colonization and Invasive Disease in Cambodian Children

Author

Turner, Paul, primary, Leab, Phana, primary, Ly, Sokeng, primary, Sao, Sena, primary, Miliya, Thyl, primary, Heffelfinger, James D, primary, Batmunkh, Nyambat, primary, Lessa, Fernanda C, primary, Walldorf, Jenny A, primary, Hyde, Terri B, primary, Ork, Vichit, primary, Hossain, Md Shafiqul, primary, Gould, Katherine A, primary, Hinds, Jason, primary, Cooper, Ben S, primary, Ngoun, Chanpheaktra, primary, Turner, Claudia, primary, and Day, Nicholas P J, primary

Published
2019
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205. Determination of Optimal Diagnostic Cut-Offs for the Naval Medical Research Center Scrub Typhus IgM ELISA in Chiang Rai, Thailand

Author

Phanichkrivalkosil, Meghna, primary, Tanganuchitcharnchai, Ampai, additional, Jintaworn, Suthatip, additional, Kantipong, Pacharee, additional, Laongnualpanich, Achara, additional, Chierakul, Wirongrong, additional, Paris, Daniel H., additional, Richards, Allen L., additional, Wangrangsimakul, Tri, additional, Day, Nicholas P. J., additional, and Blacksell, Stuart D., additional

Published
2019
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206. Community engagement, social context and coverage of mass anti-malarial administration: Comparative findings from multi-site research in the Greater Mekong sub-Region

Author

Pell, Christopher L., primary, Adhikari, Bipin, additional, Myo Thwin, May, additional, Kajeechiwa, Ladda, additional, Nosten, Suphak, additional, Nosten, Francois H., additional, Sahan, Kate M., additional, Smithuis, Frank M., additional, Nguyen, Thuy-Nhien, additional, Hien, Tran Tinh, additional, Tripura, Rupam, additional, Peto, Thomas J., additional, Sanann, Nou, additional, Nguon, Chea, additional, Pongvongsa, Tiengkham, additional, Phommasone, Koukeo, additional, Mayxay, Mayfong, additional, Mukaka, Mavuto, additional, Peerawaranun, Pimnara, additional, Kaehler, Nils, additional, Cheah, Phaik Yeong, additional, Day, Nicholas P. J., additional, White, Nicholas J., additional, Dondorp, Arjen M., additional, and von Seidlein, Lorenz, additional

Published
2019
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207. Efficacy of Primaquine in Preventing Short- and Long-Latency Plasmodium vivax Relapses in Nepal

Author

Rijal, Komal Raj, primary, Adhikari, Bipin, additional, Ghimire, Prakash, additional, Banjara, Megha Raj, additional, Das Thakur, Garib, additional, Hanboonkunupakarn, Borimas, additional, Imwong, Mallika, additional, Chotivanich, Kesinee, additional, Day, Nicholas P J, additional, White, Nicholas J, additional, and Pukrittayakamee, Sasithon, additional

Published
2019
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212. Improving statistical power in severe malaria genetic association studies by augmenting phenotypic precision.

Author

Watson, James A., Ndila, Carolyne M., Uyoga, Sophie, Macharia, Alexander, Nyutu, Gideon, Mohammed, Shebe, Ngetsa, Caroline, Mturi, Neema, Peshu, Norbert, Tsofa, Benjamin, Rockett, Kirk, Leopold, Stije, Kingston, Hugh, George, Elizabeth C., Maitland, Kathryn, Day, Nicholas P. J., Dondorp, Arjen M., Bejon, Philip, Williams, Thomas, and Holmes, Chris C.

Published
2021
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213. Post-malaria neurological syndrome

Author

Mai, Nguyen Thi Hoang, Day, Nicholas P. J., Chuong, Ly Van, Waller, Deborah, Phu, Nguyen Hoan, Bethell, Delia B., Hien, Tran Tinh, and White, Nicholas J.

Published
1996

218. Role of Burkholderia pseudomallei-Specific IgG2 in Adults with Acute Melioidosis, Thailand.

Author

Panjaporn Chaichana, Kemajittra Jenjaroen, Suchintana Chumseng, Manutsanun Sumonwiriya, Patpong Rongkard, Kronsteiner, Barbara, Teparrukkul, Prapit, Limmathurotsakul, Direk, Day, Nicholas P. J., Chantratita, Narisara, Dunachie, Susanna J., Chaichana, Panjaporn, Jenjaroen, Kemajittra, Chumseng, Suchintana, Sumonwiriya, Manutsanun, and Rongkard, Patpong

Subjects
MELIOIDOSIS, BURKHOLDERIA, PHAGOCYTIC function tests, PHAGOCYTOSIS, BURKHOLDERIA pseudomallei, CD14 antigen, LOGISTIC regression analysis, RESEARCH, IMMUNOGLOBULINS, RESEARCH methodology, MEDICAL cooperation, EVALUATION research, COMPARATIVE studies, ENZYME-linked immunosorbent assay, RESEARCH funding
Abstract

Melioidosis is a life-threatening infectious disease caused by the gram-negative bacillus Burkholderia pseudomallei. An effective vaccine is needed, but data on protective immune responses in human melioidosis are lacking. We used ELISA and an antibody-dependent cellular phagocytosis assay to identify the major features of protective antibodies in patients with acute melioidosis in Thailand. We found that high levels of B. pseudomallei-specific IgG2 are associated with protection against death in a multivariable logistic regression analysis adjusting for age, diabetes, renal disease, and neutrophil count. Serum from melioidosis survivors enhanced bacteria uptake into human monocytes expressing FcγRIIa-H/R131, an intermediate-affinity IgG2-receptor, compared with serum from nonsurvivors. We did not find this enhancement when using monocytes carrying the low IgG2-affinity FcγRIIa-R131 allele. The findings indicate the importance of IgG2 in protection against death in human melioidosis, a crucial finding for antibody-based therapeutics and vaccine development. [ABSTRACT FROM AUTHOR]

Published
2021
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219. Scrub Typhus and the Misconception of Doxycycline Resistance.

Author

Wangrangsimakul, Tri, Phuklia, Weerawat, Newton, Paul N, Richards, Allen L, and Day, Nicholas P J

Subjects
DRUG resistance, FEVER, GRAM-negative bacterial diseases, TYPHUS fever, TREATMENT effectiveness, DOXYCYCLINE
Abstract

Scrub typhus, a neglected infectious disease caused by the obligate intracellular bacterium Orientia tsutsugamushi , is a major cause of fever across the Asia Pacific region with more than a billion people at risk. Treatment with antibiotics such as doxycycline or chloramphenicol is effective for the majority of patients. In the 1990s, reports from northern Thailand raised a troubling observation; some scrub typhus patients responded poorly to doxycycline, which investigators attributed to doxycycline resistance. Despite the controversial nature of these reports, independent verification was neglected, with subsequent studies speculating on the role of doxycycline resistance in contributing to failure of treatment or prophylaxis. In this review, we have outlined the evidence for drug-resistant Orientia tsutsugamushi , assessed the evidence for doxycycline resistance, and highlight more recent findings unsupportive of doxycycline resistance. We conclude that doxycycline resistance is a misconception, with treatment outcome likely to be determined by other bacterial, host, and pharmacological factors. [ABSTRACT FROM AUTHOR]

Published
2020
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220. Clinical Characteristics and Outcome of Children Hospitalized With Scrub Typhus in an Area of Endemicity.

Author

Wangrangsimakul, Tri, Greer, Rachel C, Chanta, Chulapong, Nedsuwan, Supalert, Blacksell, Stuart D, Day, Nicholas P J, and Paris, Daniel H

Subjects
ANTIBIOTICS, HOSPITAL care of children, GRAM-negative bacterial diseases, IMMUNOGLOBULINS, POLYMERASE chain reaction, TREATMENT effectiveness, DESCRIPTIVE statistics, FLUOROIMMUNOASSAY, DISEASE complications, SYMPTOMS, CHILDREN
Abstract

Background Scrub typhus, caused by Orientia tsutsugamushi , is a major cause of acute febrile illness in children in the rural tropics. Methods We recruited 60 febrile pediatric patients with a positive scrub typhus rapid diagnostic test result and 40 healthy controls from Chiang Rai Province in northern Thailand. Diagnosis was confirmed by the detection of (1) O. tsutsugamushi– specific DNA in blood or eschar samples with a polymerase chain reaction assay, (2) a fourfold rise in immunoglobulin M (IgM) titer to ≥1:3200 in paired plasma samples with an indirect immunofluorescence assay (IFA), or (3) a single IgM titer of ≥1:3200 in an acute plasma sample with an IFA. Demographic, clinical, and laboratory data were collected, and patients were followed up for 1 year. Results Diagnosis was confirmed in 35 (58%) of 60 patients, and all controls tested negative for scrub typhus. Patients with confirmed scrub typhus had clinical symptoms, including fever (35 of 35 [100%]), eschar (21 of 35 [60%]), cough (21 of 35 [60%]), tachypnea (16 of 35 [46%]), lymphadenopathy (15 of 35 [43%]), and headache (14 of 35 [40%]). Only 4 (11%) of 35 patients received appropriate antibiotic treatment for scrub typhus before admission. The median fever-clearance time was 36 hours (interquartile range, 24–53 hours). Complications observed include hepatitis (9 of 35 [26%]), severe thrombocytopenia (7 of 35 [20%]), pneumonitis (5 of 35 [14%]), circulatory shock (4 of 35 [11%]), and acute respiratory distress syndrome (3 of 35 [9%]). Treatment failure, defined by failure to defervesce within 72 hours of antibiotic treatment initiation, was noted in 8 (23%) of 35 patients, and 1 (3%) of the 35 patients died. No evidence of relapse or reinfection was found. Conclusion Pediatric scrub typhus in northern Thailand is often severe and potentially fatal with delays in treatment a likely contributing factor. Additional studies to investigate the bacterial, pharmacologic, and immunologic factors related to treatment outcome along with measures to improve public awareness should be prioritized. [ABSTRACT FROM AUTHOR]

Published
2020
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221. Reduced Cardiac Index Reserve and Hypovolemia in Severe Falciparum Malaria.

Author

Kingston, Hugh W. F., Ghose, Aniruddha, Rungpradubvong, Voravut, Satitthummanid, Sudarat, Herdman, M. Trent, Plewes, Katherine, Leopold, Stije J., Ishioka, Haruhiko, Mohanty, Sanjib, Maude, Richard J., Schultz, Marcus J., Lagrand, Wim K., Hossain, Md Amir, Day, Nicholas P. J., White, Nicholas J., Anstey, Nicholas M., and Dondorp, Arjen M.

Abstract

Background. Impaired microvascular perfusion is central to the development of coma and lactic acidosis in severe falciparum malaria. Refractory hypotension is rare on admission but develops frequently in fatal cases. We assessed cardiac function and volume status in severe falciparum malaria and its prognostic significance. Methods. Patients with severe (N = 101) or acute uncomplicated falciparum malaria (N = 83) were recruited from 2 hospitals in India and Bangladesh, and healthy participants (N = 44) underwent echocardiography. Results. Patients with severe malaria had 38% shorter left ventricular (LV) filling times and 25% shorter LV ejection times than healthy participants because of tachycardia; however, stroke volume, LV internal diameter in diastole (LVIDd), and LV internal diameter in systole (LVIDs) indices were similar. A low endocardial fraction shortening (eFS) was present in 17% (9 of 52) of severe malaria patients. Adjusting for preload and afterload, eFS was similar in health and severe malaria. Fatal cases had smaller baseline LVIDd and LVIDs indices, more collapsible inferior vena cavae (IVC), and higher heart rates than survivors. The LVIDs and IVC collapsibility were independent predictors for mortality, together with base excess and Glasgow Coma Scale. Conclusions. Patients with severe malaria have rapid ejection of a normal stroke volume. Fatal cases had features of relative hypovolemia and reduced cardiac index reserve. [ABSTRACT FROM AUTHOR]

Published
2020
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222. Impact of 13-Valent Pneumococcal Conjugate Vaccine on Colonization and Invasive Disease in Cambodian Children.

Author

Turner, Paul, Leab, Phana, Ly, Sokeng, Sao, Sena, Miliya, Thyl, Heffelfinger, James D, Batmunkh, Nyambat, Lessa, Fernanda C, Walldorf, Jenny A, Hyde, Terri B, Ork, Vichit, Hossain, Md Shafiqul, Gould, Katherine A, Hinds, Jason, Cooper, Ben S, Ngoun, Chanpheaktra, Turner, Claudia, and Day, Nicholas P J

Subjects
CONFIDENCE intervals, HOST-bacteria relationships, PNEUMOCOCCAL vaccines, STREPTOCOCCAL diseases, STREPTOCOCCUS, TREATMENT effectiveness, PRE-tests & post-tests, DESCRIPTIVE statistics, PHARMACODYNAMICS, CHILDREN
Abstract

Background Cambodia introduced the 13-valent pneumococcal conjugate vaccine (PCV13) in January 2015 using a 3 + 0 dosing schedule and no catch-up campaign. We investigated the effects of this introduction on pneumococcal colonization and invasive disease in children aged <5 years. Methods There were 6 colonization surveys done between January 2014 and January 2018 in children attending the outpatient department of a nongovernmental pediatric hospital in Siem Reap. Nasopharyngeal swabs were analyzed by phenotypic and genotypic methods to detect pneumococcal serotypes and antimicrobial resistance. Invasive pneumococcal disease (IPD) data for January 2012–December 2018 were retrieved from hospital databases. Pre-PCV IPD data and pre-/post-PCV colonization data were modelled to estimate vaccine effectiveness (VE). Results Comparing 2014 with 2016–2018, and using adjusted prevalence ratios, VE estimates for colonization were 16.6% (95% confidence interval [CI] 10.6–21.8) for all pneumococci and 39.2% (95% CI 26.7–46.1) for vaccine serotype (VT) pneumococci. There was a 26.0% (95% CI 17.7–33.0) decrease in multidrug-resistant pneumococcal colonization. The IPD incidence was estimated to have declined by 26.4% (95% CI 14.4–35.8) by 2018, with a decrease of 36.3% (95% CI 23.8–46.9) for VT IPD and an increase of 101.4% (95% CI 62.0–145.4) for non-VT IPD. Conclusions Following PCV13 introduction into the Cambodian immunization schedule, there have been declines in VT pneumococcal colonization and disease in children aged <5 years. Modelling of dominant serotype colonization data produced plausible VE estimates. [ABSTRACT FROM AUTHOR]

Published
2020
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223. Human Immune Responses to Melioidosis and Cross-Reactivity to Low-Virulence Burkholderia Species, Thailand1.

Author

Rongkard, Patpong, Kronsteiner, Barbara, Hantrakun, Viriya, Jenjaroen, Kemajittra, Sumonwiriya, Manutsanun, Chaichana, Panjaporn, Chumseng, Suchintana, Chantratita, Narisara, Wuthiekanun, Vanaporn, Fletcher, Helen A., Teparrukkul, Prapit, Limmathurotsakul, Direk, Day, Nicholas P. J., and Dunachie, Susanna J.

Subjects
MELIOIDOSIS, BURKHOLDERIA, IMMUNE response, BURKHOLDERIA pseudomallei, TROPICAL medicine, IMMUNITY in fish, HUMORAL immunity, CELLULAR immunity
Abstract

Melioidosis is a neglected tropical disease with an estimated annual mortality rate of 89,000 in 45 countries across tropical regions. The causative agent is Burkholderia pseudomallei, a gram-negative soil-dwelling bacterium. In Thailand, B. pseudomallei can be found across multiple regions, along with the low-virulence B. thailandensis and the recently discovered B. thailandensis variant (BTCV), which expresses B. pseudomallei-like capsular polysaccharide. Comprehensive studies of human immune responses to B. thailandensis variants and cross-reactivity to B. pseudomallei are not complete. We evaluated human immune responses to B. pseudomallei, B. thailandensis, and BTCV in melioidosis patients and healthy persons in B. pseudomallei-endemic areas using a range of humoral and cellular immune assays. We found immune cross-reactivity to be strong for both humoral and cellular immunity among B. pseudomallei, B. thailandensis, and BTCV. Our findings suggest that environmental exposure to low-virulence strains may build cellular immunity to B. pseudomallei. [ABSTRACT FROM AUTHOR]

Published
2020
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224. Estimating the probable cause of recurrence in Plasmodium vivax malaria: relapse, reinfection or recrudescence?

Author

Taylor, Aimee R, primary, Watson, James A, additional, Chu, Cindy S, additional, Puaprasert, Kanokpich, additional, Duanguppama, Jureeporn, additional, Day, Nicholas P J, additional, Nosten, Francois, additional, Neafsey, Daniel E, additional, Buckee, Caroline O, additional, Imwong, Mallika, additional, and White, Nicholas J, additional

Published
2018
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225. Identifying the Components of Acidosis in Patients With Severe Plasmodium falciparum Malaria Using Metabolomics

Author

Leopold, Stije J, primary, Ghose, Aniruddha, additional, Allman, Erik L, additional, Kingston, Hugh W F, additional, Hossain, Amir, additional, Dutta, Asok Kumar, additional, Plewes, Katherine, additional, Chotivanich, Kesinee, additional, Day, Nicholas P J, additional, Tarning, Joel, additional, Winterberg, Markus, additional, White, Nicholas J, additional, Llinás, Manuel, additional, and Dondorp, Arjen M, additional

Published
2018
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226. Point-of-care lung ultrasound for the detection of pulmonary manifestations of malaria and sepsis: An observational study

Author

Leopold, Stije J., primary, Ghose, Aniruddha, additional, Plewes, Katherine A., additional, Mazumder, Subash, additional, Pisani, Luigi, additional, Kingston, Hugh W. F., additional, Paul, Sujat, additional, Barua, Anupam, additional, Sattar, M. Abdus, additional, Huson, Michaëla A. M., additional, Walden, Andrew P., additional, Henwood, Patricia C., additional, Riviello, Elisabeth D., additional, Schultz, Marcus J., additional, Day, Nicholas P. J., additional, Kumar Dutta, Asok, additional, White, Nicholas J., additional, and Dondorp, Arjen M., additional

Published
2018
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227. Perceptions of asymptomatic malaria infection and their implications for malaria control and elimination in Laos

Author

Adhikari, Bipin, primary, Phommasone, Koukeo, additional, Pongvongsa, Tiengkham, additional, Soundala, Xayaphone, additional, Koummarasy, Palingnaphone, additional, Henriques, Gisela, additional, Peto, Thomas J., additional, Seidlein, Lorenz von, additional, White, Nicholas J., additional, Day, Nicholas P. J., additional, Dondorp, Arjen M., additional, Newton, Paul N., additional, Cheah, Phaik Yeong, additional, Mayxay, Mayfong, additional, and Pell, Christopher, additional

Published
2018
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228. Antibodies in Melioidosis: The Role of the Indirect Hemagglutination Assay in Evaluating Patients and Exposed Populations

Author

Chaichana, Panjaporn, primary, Jenjaroen, Kemajittra, additional, Amornchai, Premjit, additional, Chumseng, Suchintana, additional, Langla, Sayan, additional, Rongkard, Patpong, additional, Sumonwiriya, Manutsanun, additional, Jeeyapant, Atthanee, additional, Chantratita, Narisara, additional, Teparrukkul, Prapit, additional, Limmathurotsakul, Direk, additional, Day, Nicholas P. J., additional, Wuthiekanun, Vanaporn, additional, and Dunachie, Susanna J., additional

Published
2018
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230. Malaria elimination in remote communities requires integration of malaria control activities into general health care: an observational study and interrupted time series analysis in Myanmar

Author

McLean, Alistair R. D., primary, Wai, Hla Phyo, additional, Thu, Aung Myat, additional, Khant, Zay Soe, additional, Indrasuta, Chanida, additional, Ashley, Elizabeth A., additional, Kyaw, Thar Tun, additional, Day, Nicholas P. J., additional, Dondorp, Arjen, additional, White, Nicholas J., additional, and Smithuis, Frank M., additional

Published
2018
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231. Thrombocytopenia Impairs Host Defense AgainstBurkholderia pseudomallei(Melioidosis)

Author

Birnie, Emma, primary, Claushuis, Theodora A M, additional, Koh, Gavin C K W, additional, Limmathurotsakul, Direk, additional, Day, Nicholas P J, additional, Roelofs, Joris J T H, additional, Ware, Jerry, additional, Hou, Baidong, additional, de Vos, Alex F, additional, van der Poll, Tom, additional, van ‘t Veer, Cornelis, additional, and Wiersinga, W Joost, additional

Published
2018
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232. Asymptomatic Natural Human Infections With the Simian Malaria Parasites Plasmodium cynomolgi and Plasmodium knowlesi

Author

Imwong, Mallika, primary, Madmanee, Wanassanan, additional, Suwannasin, Kanokon, additional, Kunasol, Chanon, additional, Peto, Thomas J, additional, Tripura, Rupam, additional, von Seidlein, Lorenz, additional, Nguon, Chea, additional, Davoeung, Chan, additional, Day, Nicholas P J, additional, Dondorp, Arjen M, additional, and White, Nicholas J, additional

Published
2018
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234. Clinical epidemiology and outcomes of community acquired infection and sepsis among hospitalized patients in a resource limited setting in Northeast Thailand: A prospective observational study (Ubon-sepsis)

Author

Hantrakun, Viriya, primary, Somayaji, Ranjani, additional, Teparrukkul, Prapit, additional, Boonsri, Chaiyaporn, additional, Rudd, Kristina, additional, Day, Nicholas P. J., additional, West, T. Eoin, additional, and Limmathurotsakul, Direk, additional

Published
2018
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237. Epidemiology of Plasmodium vivax Malaria Infection in Nepal

Author

Rijal, Komal Raj, primary, Adhikari, Bipin, additional, Ghimire, Prakash, additional, Banjara, Megha Raj, additional, Hanboonkunupakarn, Borimas, additional, Imwong, Mallika, additional, Chotivanich, Kesinee, additional, Ceintury, Kedar Prasad, additional, Lal, Bibek Kumar, additional, Das Thakur, Garib, additional, Day, Nicholas P. J., additional, White, Nicholas J., additional, and Pukrittayakamee, Sasithon, additional

Published
2018
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240. A Pilot Study to Assess Safety and Feasibility of Intrathecal Immunoglobulin for the Treatment of Adults with Tetanus

Author

Loan, Huynh Thi, primary, Yen, Lam Minh, additional, Kestelyn, Evelyne, additional, Hao, Nguyen Van, additional, Mai, Nguyen Thi Hoang, additional, Thuy, Duong Bich, additional, Duong, Ha Thi Hai, additional, Dung, Nguyen Thi Phuong, additional, Phu, Nguyen Hoan, additional, Lieu, Pham Thi, additional, Thanh, Tran Tan, additional, Geskus, Ronald, additional, van Doorn, H. Rogier, additional, Tan, Le Van, additional, Wyncoll, Duncan, additional, Day, Nicholas P. J., additional, Hien, Tran Tinh, additional, Thwaites, Guy E., additional, Chau, Nguyen Van Vinh, additional, and Thwaites, C. Louise, additional

Published
2018
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241. Genetic polymorphisms in the circumsporozoite protein of Plasmodium malariae show a geographical bias

Author

Saralamba, Naowarat, primary, Mayxay, Mayfong, additional, Newton, Paul N., additional, Smithuis, Frank, additional, Nosten, Francois, additional, Archasuksan, Laypaw, additional, Pukrittayakamee, Sasithon, additional, White, Nicholas J., additional, Day, Nicholas P. J., additional, Dondorp, Arjen M., additional, and Imwong, Mallika, additional

Published
2018
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242. Effectiveness and safety of 3 and 5 day courses of artemether–lumefantrine for the treatment of uncomplicated falciparum malaria in an area of emerging artemisinin resistance in Myanmar

Author

Tun, Kyaw Myo, primary, Jeeyapant, Atthanee, additional, Myint, Aung Hpone, additional, Kyaw, Zwe Thiha, additional, Dhorda, Mehul, additional, Mukaka, Mavuto, additional, Cheah, Phaik Yeong, additional, Imwong, Mallika, additional, Hlaing, Thaung, additional, Kyaw, Thar Htun, additional, Ashley, Elizabeth A., additional, Dondorp, Arjen, additional, White, Nicholas J., additional, Day, Nicholas P. J., additional, and Smithuis, Frank, additional

Published
2018
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246. Acidosis and acute kidney injury in severe malaria

Author

Sriboonvorakul, Natthida, primary, Ghose, Aniruddha, additional, Hassan, M. Mahtab Uddin, additional, Hossain, Md. Amir, additional, Faiz, M. Abul, additional, Pukrittayakamee, Sasithon, additional, Chotivanich, Kesinee, additional, Sukthana, Yaowalark, additional, Leopold, Stije J., additional, Plewes, Katherine, additional, Day, Nicholas P. J., additional, White, Nicholas J., additional, Tarning, Joel, additional, and Dondorp, Arjen M., additional

Published
2018
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247. Predicting the severity of dengue fever in children on admission based on clinical features and laboratory indicators: application of classification tree analysis

Author

Phakhounthong, Khansoudaphone, primary, Chaovalit, Pimwadee, additional, Jittamala, Podjanee, additional, Blacksell, Stuart D., additional, Carter, Michael J., additional, Turner, Paul, additional, Chheng, Kheng, additional, Sona, Soeung, additional, Kumar, Varun, additional, Day, Nicholas P. J., additional, White, Lisa J., additional, and Pan-ngum, Wirichada, additional

Published
2018
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248. Acetaminophen as a Renoprotective Adjunctive Treatment in Patients With Severe and Moderately Severe Falciparum Malaria: A Randomized, Controlled, Open-Label Trial

Author

Plewes, Katherine, primary, Kingston, Hugh W F, additional, Ghose, Aniruddha, additional, Wattanakul, Thanaporn, additional, Hassan, Md Mahtab Uddin, additional, Haider, Md Shafiul, additional, Dutta, Prodip K, additional, Islam, Md Akhterul, additional, Alam, Shamsul, additional, Jahangir, Selim Md, additional, Zahed, A S M, additional, Sattar, Md Abdus, additional, Chowdhury, M A Hassan, additional, Herdman, M Trent, additional, Leopold, Stije J, additional, Ishioka, Haruhiko, additional, Piera, Kim A, additional, Charunwatthana, Prakaykaew, additional, Silamut, Kamolrat, additional, Yeo, Tsin W, additional, Lee, Sue J, additional, Mukaka, Mavuto, additional, Maude, Richard J, additional, Turner, Gareth D H, additional, Faiz, Md Abul, additional, Tarning, Joel, additional, Oates, John A, additional, Anstey, Nicholas M, additional, White, Nicholas J, additional, Day, Nicholas P J, additional, Hossain, Md Amir, additional, Roberts II, L Jackson, additional, and Dondorp, Arjen M, additional

Published
2018
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249. Characterization of the rhesus macaque (Macaca mulatta) scrub typhus model: Susceptibility to intradermal challenge with the human pathogen Orientia tsutsugamushi Karp

Author

Sunyakumthorn, Piyanate, primary, Somponpun, Suwit J., additional, Im-erbsin, Rawiwan, additional, Anantatat, Tippawan, additional, Jenjaroen, Kemajittra, additional, Dunachie, Susanna J., additional, Lombardini, Eric D., additional, Burke, Robin L., additional, Blacksell, Stuart D., additional, Jones, James W., additional, Mason, Carl J., additional, Richards, Allen L., additional, Day, Nicholas P. J., additional, and Paris, Daniel H., additional

Published
2018
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250. A Controlled Trial of Mass Drug Administration to Interrupt Transmission of Multidrug-Resistant Falciparum Malaria in Cambodian Villages

Author

Tripura, Rupam, primary, Peto, Thomas J, additional, Chea, Nguon, additional, Chan, Davoeung, additional, Mukaka, Mavuto, additional, Sirithiranont, Pasathorn, additional, Dhorda, Mehul, additional, Promnarate, Cholrawee, additional, Imwong, Mallika, additional, von Seidlein, Lorenz, additional, Duanguppama, Jureeporn, additional, Patumrat, Krittaya, additional, Huy, Rekol, additional, Grobusch, Martin P, additional, Day, Nicholas P J, additional, White, Nicholas J, additional, and Dondorp, Arjen M, additional

Published
2018
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