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205. Model reduction for coupled free flow over porous media: a hybrid dimensional pore network model approach

Author

Weishaupt, Kilian, Terzis, Alexandros, Zarikos, Ioannis, Yang, Guang, de Winter, Matthijs, and Helmig, Rainer

Subjects
Physics - Computational Physics, Physics - Fluid Dynamics
Abstract

Modeling coupled systems of free flow adjacent to a porous medium by means of fully resolved Navier-Stokes equations is limited by the immense computational cost and is thus only feasible for relatively small domains. Model reduction allows to decrease a model's complexity while maintaining an acceptable degree of accuracy. Starting from a fully resolved three-dimensional numerical model, which is compared to high-resolution micro-PIV experimental data obtained from a previous study (Terzis et al.,2019), we perform a two-fold model reduction: first, a quasi-3D model incorporating a wall friction term is successfully compared to the fully resolved model. Second, we employ a pore-network model to account for the porous part of the domain and couple it to the quasi-3D model which still resolves the free-flow part of the domain (Weishaupt et al., 2019). We have extended this coupling approach here to include slip velocities at the pore throats intersecting with the free-flow domain. The proposed method is simple, accurate and comes at no additional run-time penalty. The coupled model deviates by less than 10 % from the other two model concepts. Several hours of run-time was required for the three-dimensional model compared to eleven and five minutes necessary for the quasi-3D and coupled model which highlights the benefits of model reduction.

Published
2019

207. A result on polynomials derived via graph theory

Author

Coulter, Robert S., De Winter, Stefaan, Kodess, Alex, and Lazebnik, Felix

Subjects
Mathematics - Combinatorics
Abstract

We present an example of a result in graph theory that is used to obtain a result in another branch of mathematics. More precisely, we show that the isomorphism of certain directed graphs implies that some trinomials over finite fields have the same number of roots.

Published
2019

208. Bridging the Gap: 3D Real-Space Characterization of Colloidal Assemblies via FIB-SEM Tomography

Author

van der Hoeven, Jessi E. S., van der Wee, Ernest B., de Winter, D. A. Matthijs, Hermes, Michiel, Liu, Yang, Fokkema, Jantina, Bransen, Maarten, van Huis, Marijn A., Gerritsen, Hans C., de Jongh, Petra E., and van Blaaderen, Alfons

Subjects
Condensed Matter - Soft Condensed Matter, Condensed Matter - Materials Science
Abstract

Insight in the structure of nanoparticle assemblies up to a single particle level is key to understand the collective properties of these assemblies, which critically depend on the individual particle positions and orientations. However, the characterization of large, micron sized assemblies containing small, 10-500 nanometer, sized colloids is highly challenging and cannot easily be done with the conventional light, electron or X-ray microscopy techniques. Here, we demonstrate that focused ion beam-scanning electron microscopy (FIB-SEM) tomography in combination with image processing enables quantitative real-space studies of ordered and disordered particle assemblies too large for conventional transmission electron tomography, containing particles too small for confocal microscopy. First, we demonstrate the high resolution structural analysis of spherical nanoparticle assemblies, containing small anisotropic gold nanoparticles. Herein, FIB-SEM tomography allows the characterization of assembly dimensions which are inaccessible to conventional transmission electron microscopy. Next, we show that FIB-SEM tomography is capable of characterizing much larger ordered and disordered assemblies containing silica colloids with a diameter close to the resolution limit of confocal microscopes. We determined both the position and the orientation of each individual (nano)particle in the assemblies by using recently developed particle tracking routines. Such high precision structural information is essential in the understanding and design of the collective properties of new nanoparticle based materials and processes., Comment: 17 pages, 4 figures, Supplemental Information at articles webpage: https://doi.org/10.1039/C8NR09753D

Published
2019
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209. Hemolytic disease of the fetus and newborn: systematic literature review of the antenatal landscape

Author

Derek P. de Winter, Allysen Kaminski, May Lee Tjoa, and Dick Oepkes

Subjects
Hemolytic disease of the fetus and newborn, Fetal therapy, Fetal anemia, Intrauterine transfusion, Gynecology and obstetrics, RG1-991
Abstract

Abstract Background Prevention of pregnancy-related alloimmunization and the management of hemolytic disease of the fetus and newborn (HDFN) has significantly improved over the past decades. Considering improvements in HDFN care, the objectives of this systematic literature review were to assess the prenatal treatment landscape and outcomes of Rh(D)- and K-mediated HDFN in mothers and fetuses, to identify the burden of disease, to identify evidence gaps in the literature, and to provide recommendations for future research. Methods We performed a systematic search on MEDLINE, EMBASE and clinicaltrials.gov. Observational studies, trials, modelling studies, systematic reviews of cohort studies, and case reports and series of women and/or their fetus with HDFN caused by Rhesus (Rh)D or Kell alloimmunization. Extracted data included prevalence; treatment patterns; clinical outcomes; treatment efficacy; and mortality. Results We identified 2,541 articles. After excluding 2,482 articles and adding 1 article from screening systematic reviews, 60 articles were selected. Most abstracted data were from case reports and case series. Prevalence was 0.047% and 0.006% for Rh(D)- and K-mediated HDFN, respectively. Most commonly reported antenatal treatment was intrauterine transfusion (IUT; median frequency [interquartile range]: 13.0% [7.2–66.0]). Average gestational age at first IUT ranged between 25 and 27 weeks. weeks. This timing is early and carries risks, which were observed in outcomes associated with IUTs. The rate of hydrops fetalis among pregnancies with Rh(D)-mediated HDFN treated with IUT was 14.8% (range, 0–50%) and 39.2% in K-mediated HDFN. Overall mean ± SD fetal mortality rate that was found to be 19.8%±29.4% across 19 studies. Mean gestational age at birth ranged between 34 and 36 weeks. Conclusion These findings corroborate the rareness of HDFN and frequently needed intrauterine transfusion with inherent risks, and most births occur at a late preterm gestational age. We identified several evidence gaps providing opportunities for future studies.

Published
2023
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210. Trajectories of stressful life events and long-term changes in mental health outcomes, moderated by family functioning? the TRAILS study

Author

Lisette Wijbenga, Sijmen A. Reijneveld, Josue Almansa, Eliza L. Korevaar, Jacomijn Hofstra, and Andrea F. de Winter

Subjects
Adolescence, Young adults, Stressful life events, Life course, Mental health, Family functioning, Pediatrics, RJ1-570, Psychiatry, RC435-571
Abstract

Abstract Purpose We assessed the association between trajectories of stressful life events (SLEs) throughout adolescence and changes in mental health from childhood to young adulthood. Further, we assessed whether family functioning moderated this association. Methods Data of the first six waves of the TRAILS study (2001-2016; n = 2229) were used, a cohort followed from approximately age 11 to 23. We measured SLEs (death of a family member or other beloved one, delinquency, moving, victim of violence, parental divorce, and sexual harassment) at ages 14, 16 and 19. Family functioning was measured at all six time points using the Family Assessment Device (FAD), and mental health was measured through the Youth/Adult Self-Report at ages 11 and 23. Latent class growth analyses (LCGA) were used to examine longitudinal trajectories and associations. Results We identified three SLE trajectories (low, middle, high) throughout adolescence, and found no significant associations between these trajectories and changes in mental health from childhood to young adulthood. Family functioning and SLE trajectories were significantly associated, however, the association of SLE trajectories and changes in mental health was not modified by family functioning. Mental health problems at age 11 increased the likelihood of high SLE trajectories during adolescence, and of experiencing negative family functioning. Conclusion Experiencing SLEs throughout adolescence does not have a direct impact on changes in mental health from childhood to young adulthood, but early adolescence mental health problems increase the likelihood of experiencing SLEs.

Published
2022
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211. The effect of physician training and patient education on the discussion of care decisions at the internal medicine outpatient clinic

Author

Saskia Briedé, Maria A. de Winter, Tessa C. van Charldorp, and Karin A. H. Kaasjager

Subjects
Care decisions, Treatment limitations, Outpatient clinic, Provider-patient communication, Communication training, Patient education, Public aspects of medicine, RA1-1270
Abstract

Abstract Background Care decision discussions are intended to align treatment with the patient’s wishes, goals and values. To overcome the numerous barriers to such discussions, physicians as well as patients need tailored support. We evaluate the effect of a physicians’ training and a conversation aid for patients about care decisions on patient and physician outcomes. Methods At the internal medicine outpatient clinic of the University Medical Centre Utrecht, a 1:1 randomized, parallel-group study (patient conversation aid) was combined with a pre-post intervention (physicians’ training) design. Primary outcome was patient satisfaction, secondary outcomes were patient-doctor relationship, shared-decision-making, doctor preparedness and patient appreciation of the conversation aid. Results Between October 2018 and February 2020 11 physicians (36% residents, 73% female) and 185 patients (median age 58 years (interquartile range (IQR) 50–68), 60% male) participated. Only 28% of the patients reported a care decision discussion during the consultation. We found no effect of the interventions on patient satisfaction (effect sizes -0.14 (95% confidence interval (CI) -0.56–0.27) for conversation aid; 0.04 (95% CI -0.40–0.48) for physician’s training), nor on the patient-doctor relationship or shared-decision-making. However, physicians felt more prepared to discuss care decisions after training (median 3 (IQR 1–4) vs 1 (IQR 0–3), p = 0.015). Patients assessed the conversation aid informative and gave an overall mark of median 7 (IQR 7–8). Conclusions First steps towards fruitful discussions about care decisions were made: patients considered the conversation aid informative and physicians felt better prepared to discuss care decisions after training. The low number of care decision conversations patients reported shows exactly how important it is to focus on interventions that facilitate these discussions, for both the patient and physician. Further work needs to be done to establish the best way to empower patients and physicians. Trial registration Dutch trial register, trial 6998 (NTR 7188), registered 04/05/2018, https://www.trialregister.nl/trial/6998 .

Published
2022
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212. The effect of therapeutic drug monitoring of risperidone and aripiprazole on weight gain in children and adolescents: the SPACe 2: STAR (trial) protocol of an international multicentre randomised controlled trial

Author

Rebecca A. Hermans, Lisa T. Ringeling, Kajie Liang, Sanne M. Kloosterboer, Brenda C. M. de Winter, Manon H. J. Hillegers, Birgit C. P. Koch, and Bram Dierckx

Subjects
Randomised controlled trial, Antipsychotic drugs, Risperidone, Aripiprazole, Children, Adolescents, Psychiatry, RC435-571
Abstract

Abstract Background Antipsychotic drugs are an important part of the treatment of irritability and aggression in children with an autism spectrum disorder (ASD). However, significant weight gain and metabolic disturbances are clinically relevant side effects of antipsychotic use in children. In the SPACe study, we showed positive correlations between both risperidone and aripiprazole plasma trough concentrations and weight gain over a 6-month period. The trial SPACe 2: STAR is designed as a follow-up study, in which we aim to research whether therapeutic drug monitoring in clinical practice can prevent severe weight gain, while retaining clinical effectiveness. Methods SPACe 2: STAR is an international, multicentre, randomised controlled trial (RCT). One hundred forty children aged 6 to 18 who are about to start risperidone or aripiprazole treatment for ASD related behavioural problems will be randomised into one of two groups: a therapeutic drug monitoring (TDM) group, and a care as usual (CAU) group. Participants will be assessed at baseline and 4, 10, 24, and 52 weeks follow-up. In the TDM group, physicians will receive dosing advice based on plasma levels of risperidone and aripiprazole and its metabolites at 4 and 10 weeks. Plasma levels will be measured in dried blood spots (DBS). The primary outcome will be BMI z-score at 24 weeks after start of antipsychotic treatment. Among the secondary outcomes are effectiveness, metabolic laboratory measurements, levels of prolactin, leptin and ghrelin, extrapyramidal side effects, and quality of life. Discussion This will be the first RCT evaluating the effect of TDM of antipsychotic drugs in children and adolescents. Thus, findings from SPACe 2: STAR will be of great value in optimising treatment in this vulnerable population. Trial registration ClinicalTrials.gov Identifier: NCT05146245. EudraCT number: 2020–005450-18. Sponsor protocol name: SPACe2STAR. Registered 8 June 2021. Protocol Version 6, Protocol date: 18 august 2022.

Published
2022
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213. The neurobiological basis of affect is consistent with psychological construction theory and shares a common neural basis across emotional categories

Author

Doğa Gündem, Jure Potočnik, François-Laurent De Winter, Amal El Kaddouri, Daphne Stam, Ronald Peeters, Louise Emsell, Stefan Sunaert, Lukas Van Oudenhove, Mathieu Vandenbulcke, Lisa Feldman Barrett, and Jan Van den Stock

Subjects
Biology (General), QH301-705.5
Abstract

Analysis of fMRI recordings from an autobiographical memory recall tasks suggests that neural activation during emotional experiences can be better predicted by psychological construction theory, rather than classic basic emotions theory.

Published
2022
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214. REVIEW OF WINDOW AND DOOR TYPE DETECTION APPROACHES

Author

S. De Geyter, M. Bassier, H. De Winter, and M. Vergauwen

Subjects
Technology, Engineering (General). Civil engineering (General), TA1-2040, Applied optics. Photonics, TA1501-1820
Abstract

The use of as-built Building Information Models (BIM) has become increasingly commonplace. This process of creating a BIM model from point cloud data, also referred to as Scan-to-BIM, is a mostly manual task. Due to the large amount of manual work, the entire Scan-to-BIM process is time-consuming and error prone. Current research focuses on the automation of the Scan-to-BIM pipeline by applying state-of-the-art techniques on its consecutive steps including the data acquisition, data processing, data interpretation and modelling. By automating the matching and modelling of window and door objects, a considerable amount of time can be saved in the Scan-to-BIM process. This is so because each window and door instance needs to be examined by the modeller and must be adapted to the actual on-site situation. Large object libraries containing predefined window and door objects exists but the matching to the best-fit predefined object remains time consuming. The aim of this research is to examine the possibilities to speed up the modelling of window and door objects. First, a literature review discussing existing methods for window and door detection and matching is presented. Second, the acquired data is examined to explore the capabilities of capturing window and door information for different remote sensing devices. Followed by tests of some commonplace features in the use for window and door occurrence matching and clustering.

Published
2022
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215. AUTOMATIC CALCULATION OF VOLUME CHANGES IN ROAD CONSTRUCTION

Author

H. De Winter, M. Bassier, S. De Geyter, and M. Vergauwen

Subjects
Technology, Engineering (General). Civil engineering (General), TA1-2040, Applied optics. Photonics, TA1501-1820
Abstract

The construction industry is still one of the least digitized sectors in the world, and digitization in the road construction sector in particular is even more dire. To improve the efficiency of the sector, it is of utmost importance to automate construction monitoring tasks, i.e. progress, quality and quantity analyses. The goal of the presented framework is the automation of volume calculation in road construction, so the last branch, i.e. quantity analysis. This paper discusses volume calculations in road construction sites. These volume calculations will be done based on both as-design data and as-built data, where the former is modelled by considering the regulations formulated by the Agency of Roads and Traffic, Agentschap Wegen en Verkeer (AWV) of Flanders, and the latter is captured by using an RTK-UAV. The feasibility of the proposed workflow is examined using real test cases. As a result of the automation, the homogeneity of data across projects will increase and this forms the basis for further automation in road construction. By performing these checks on a regular basis at set intervals, one can obtain a clear overview of progress. In this way, possible delays or errors can be spotted quickly, resulting in higher quality and reduced failure costs.

Published
2022
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216. International Student Mobility Aspirations: The Role of Romantic Relationships and Academic Motivation

Author

De Winter, Tom, Van Mol, Christof, and de Valk, Helga A. G.

Abstract

The academic literature on the determinants of international student mobility so far has largely ignored the influence of romantic relationships and study motivation in the development of aspirations to participate in temporary learning experiences in another country. However, young adults might take considerations about investments in individual development (via academic training and thus study motivation) and romantic relationships into account in their decision-making process. Consequently, we apply a life-course perspective analyzing the relationships between having a romantic partner, study motivation, and aspirations to participate in an international exchange program among first-year university students, based on a survey conducted among 603 freshmen in Brussels. As female students are more likely to participate in student exchanges compared with male students, we pay special attention to gender differences. Our results show that a romantic relationship is negatively correlated with aspirations to participate in an international student exchange among female students. In contrast, intrinsic academic motivation is significantly associated with such aspirations among female and male students. Overall, our findings indicate the need for the consideration of different life-course domains in academic studies on international student mobility.

Published
2021
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217. Cycling, Physics and the Teaching of Forces

Author

de Winter, James and Denton, Alan

Abstract

The bicycle is one of the greatest locomotive machines ever invented. It is also a perfect vehicle for you to teach some of the ideas that are taught in forces topics to 11- to 16-year-olds. In this article we look at some of the ways in which you can use the bicycle and cycling to provide an alternative and engaging context for teaching some of these ideas.

Published
2021

220. FDA-approved drug screening in patient-derived organoids demonstrates potential of drug repurposing for rare cystic fibrosis genotypes

Author

de Poel, E., Spelier, S., Hagemeijer, M.C., van Mourik, P., Suen, S.W.F., Vonk, A.M., Brunsveld, J.E., Ithakisiou, G.N., Kruisselbrink, E., Oppelaar, H., Berkers, G., de Winter de Groot, K.M., Heida-Michel, S., Jans, S.R., van Panhuis, H., Bakker, M., van der Meer, R., Roukema, J., Dompeling, E., Weersink, E.J.M., Koppelman, G.H., Blaazer, A.R., Muijlwijk-Koezen, J.E., van der Ent, C.K., and Beekman, J.M.

Published
2023
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223. A Solve-RD ClinVar-based reanalysis of 1522 index cases from ERN-ITHACA reveals common pitfalls and misinterpretations in exome sequencing

Author

Abbott, Kristin M., Banka, Siddharth, de Boer, Elke, Ciolfi, Andrea, Clayton-Smith, Jill, Dallapiccola, Bruno, Denommé-Pichon, Anne-Sophie, Faivre, Laurence, Gilissen, Christian, Haack, Tobias B., Havlovicova, Marketa, Hoischen, Alexander, Jackson, Adam, Kerstjens, Mieke, Kleefstra, Tjitske, Martín, Estrella López, Macek, Milan, Jr., Matalonga, Leslie, Maystadt, Isabelle, Morleo, Manuela, Nigro, Vicenzo, Pinelli, Michele, Pizzi, Simone, Posada, Manuel, Radio, Francesca C., Renieri, Alessandra, Riess, Olaf, Rooryck, Caroline, Ryba, Lukas, Agathe, Jean-Madeleine de Sainte, Santen, Gijs W.E., Schwarz, Martin, Tartaglia, Marco, Thauvin, Christel, Torella, Annalaura, Trimouille, Aurélien, Verloes, Alain, Vissers, Lisenka, Vitobello, Antonio, Votypka, Pavel, Zguro, Kristina, Boer, Elke de, Cohen, Enzo, Danis, Daniel, Gao, Fei, Horvath, Rita, Johari, Mridul, Johanson, Lennart, Li, Shuang, Morsy, Heba, Nelson, Isabelle, Paramonov, Ida, te Paske, Iris B.A.W., Robinson, Peter, Savarese, Marco, Steyaert, Wouter, Töpf, Ana, van der Velde, Joeri K., Vandrovcova, Jana, Graessner, Holm, Zurek, Birte, Ellwanger, Kornelia, Ossowski, Stephan, Demidov, German, Sturm, Marc, Schulze-Hentrich, Julia M., Schüle, Rebecca, Xu, Jishu, Kessler, Christoph, Wayand, Melanie, Synofzik, Matthis, Wilke, Carlo, Traschütz, Andreas, Schöls, Ludger, Hengel, Holger, Lerche, Holger, Kegele, Josua, Heutink, Peter, Brunner, Han, Scheffer, Hans, Hoogerbrugge, Nicoline, ‘t Hoen, Peter A.C., Vissers, Lisenka E.L.M., Sablauskas, Karolis, de Voer, Richarda M., Kamsteeg, Erik-Jan, van de Warrenburg, Bart, van Os, Nienke, Paske, Iris te, Janssen, Erik, Steehouwer, Marloes, Yaldiz, Burcu, Brookes, Anthony J., Veal, Colin, Gibson, Spencer, Maddi, Vatsalya, Mehtarizadeh, Mehdi, Riaz, Umar, Warren, Greg, Dizjikan, Farid Yavari, Shorter, Thomas, Straub, Volker, Bettolo, Chiara Marini, Manera, Jordi Diaz, Hambleton, Sophie, Engelhardt, Karin, Alexander, Elizabeth, Duffourd, Yannis, Bruel, Ange-Line, Peyron, Christine, Pélissier, Aurore, Beltran, Sergi, Gut, Ivo Glynne, Laurie, Steven, Piscia, Davide, Papakonstantinou, Anastasios, Bullich, Gemma, Corvo, Alberto, Fernandez-Callejo, Marcos, Hernández, Carles, Picó, Daniel, Lochmüller, Hanns, Gumus, Gulcin, Bros-Facer, Virginie, Rath, Ana, Hanauer, Marc, Lagorce, David, Hongnat, Oscar, Chahdil, Maroua, Lebreton, Emeline, Stevanin, Giovanni, Durr, Alexandra, Davoine, Claire-Sophie, Guillot-Noel, Léna, Heinzmann, Anna, Coarelli, Giulia, Bonne, Gisèle, Evangelista, Teresinha, Allamand, Valérie, Ben Yaou, Rabah, Metay, Corinne, Eymard, Bruno, Atalaia, Antonio, Stojkovic, Tanya, Turnovec, Marek, Thomasová, Dana, Kremliková, Radka Pourová, Franková, Vera, Havlovicová, Markéta, Lišková, Petra, Doležalová, Pavla, Parkinson, Helen, Keane, Thomas, Freeberg, Mallory, Thomas, Coline, Spalding, Dylan, Robert, Glenn, Costa, Alessia, Patch, Christine, Hanna, Mike, Houlden, Henry, Reilly, Mary, Efthymiou, Stephanie, Cali, Elisa, Magrinelli, Francesca, Sisodiya, Sanjay M., Rohrer, Jonathan, Muntoni, Francesco, Zaharieva, Irina, Sarkozy, Anna, Timmerman, Vincent, Baets, Jonathan, de Vries, Geert, De Winter, Jonathan, Beijer, Danique, de Jonghe, Peter, Van de Vondel, Liedewei, De Ridder, Willem, Weckhuysen, Sarah, Nigro, Vincenzo, Mutarelli, Margherita, Varavallo, Alessandra, Banfi, Sandro, Musacchia, Francesco, Piluso, Giulio, Ferlini, Alessandra, Selvatici, Rita, Gualandi, Francesca, Bigoni, Stefania, Rossi, Rachele, Neri, Marcella, Aretz, Stefan, Spier, Isabel, Sommer, Anna Katharina, Peters, Sophia, Oliveira, Carla, Pelaez, Jose Garcia, Matos, Ana Rita, José, Celina São, Ferreira, Marta, Gullo, Irene, Fernandes, Susana, Garrido, Luzia, Ferreira, Pedro, Carneiro, Fátima, Swertz, Morris A., Johansson, Lennart, van der Vries, Gerben, Neerincx, Pieter B., Ruvolo, David, Kerstjens Frederikse, Wilhemina S., Zonneveld-Huijssoon, Eveline, Roelofs-Prins, Dieuwke, van Gijn, Marielle, Köhler, Sebastian, Metcalfe, Alison, Drunat, Séverine, Heron, Delphine, Mignot, Cyril, Keren, Boris, Lacombe, Didier, Trimouille, Aurelien, Capella, Gabriel, Valle, Laura, Holinski-Feder, Elke, Laner, Andreas, Steinke-Lange, Verena, Cilio, Maria-Roberta, Carpancea, Evelina, Depondt, Chantal, Lederer, Damien, Sznajer, Yves, Duerinckx, Sarah, Mary, Sandrine, Macaya, Alfons, Cazurro-Gutiérrez, Ana, Pérez-Dueñas, Belén, Munell, Francina, Jarava, Clara Franco, Masó, Laura Batlle, Marcé-Grau, Anna, Colobran, Roger, Hackman, Peter, Udd, Bjarne, Hemelsoet, Dimitri, Dermaut, Bart, Schuermans, Nika, Poppe, Bruce, Verdin, Hannah, Osorio, Andrés Nascimento, Depienne, Christel, Roos, Andreas, Cordts, Isabell, Deschauer, Marcus, Striano, Pasquale, Zara, Federico, Riva, Antonella, Iacomino, Michele, Uva, Paolo, Scala, Marcello, Scudieri, Paolo, Başak, Ayşe Nazlı, Claeys, Kristl, Boztug, Kaan, Haimel, Matthias, W.E, Gijs, Ruivenkamp, Claudia A.L., Natera de Benito, Daniel, Thompson, Rachel, Polavarapu, Kiran, Grimbacher, Bodo, Zaganas, Ioannis, Kokosali, Evgenia, Lambros, Mathioudakis, Evangeliou, Athanasios, Spilioti, Martha, Kapaki, Elisabeth, Bourbouli, Mara, Radio, Francesca Clementina, Balicza, Peter, Molnar, Maria Judit, De la Paz, Manuel Posada, Sánchez, Eva Bermejo, Delgado, Beatriz Martínez, Alonso García de la Rosa, F. Javier, Schröck, Evelin, Rump, Andreas, Mei, Davide, Vetro, Annalisa, Balestrini, Simona, Guerrini, Renzo, Chinnery, Patrick F., Ratnaike, Thiloka, Schon, Katherine, Maver, Ales, Peterlin, Borut, Münchau, Alexander, Lohmann, Katja, Herzog, Rebecca, Pauly, Martje, May, Patrick, Beeson, David, Cossins, Judith, Furini, Simone, Fallerini, Chiara, Benetti, Elisa, Afenjar, Alexandra, Goldenberg, Alice, Masurel, Alice, Phan, Alice, Dieux-Coeslier, Anne, Fargeot, Anne, Guerrot, Anne-Marie, Toutain, Annick, Molin, Arnaud, Sorlin, Arthur, Putoux, Audrey, Jouret, Béatrice, Laudier, Béatrice, Demeer, Bénédicte, Doray, Bérénice, Bonniaud, Bertille, Isidor, Bertrand, Gilbert-Dussardier, Brigitte, Leheup, Bruno, Reversade, Bruno, Paul, Carle, Vincent-Delorme, Catherine, Neiva, Cecilia, Poirsier, Céline, Quélin, Chloé, Chiaverini, Christine, Coubes, Christine, Francannet, Christine, Colson, Cindy, Desplantes, Claire, Wells, Constance, Goizet, Cyril, Sanlaville, Damien, Amram, Daniel, Lehalle, Daphné, Geneviève, David, Gaillard, Dominique, Zivi, Einat, Sarrazin, Elisabeth, Steichen, Elisabeth, Schaefer, Élise, Lacaze, Elodie, Jacquemin, Emmanuel, Bongers, Ernie, Kilic, Esra, Colin, Estelle, Giuliano, Fabienne, Prieur, Fabienne, Laffargue, Fanny, Morice-Picard, Fanny, Petit, Florence, Cartault, François, Feillet, François, Baujat, Geneviève, Morin, Gilles, Diene, Gwenaëlle, Journel, Hubert, Perthus, Isabelle, Lespinasse, James, Alessandri, Jean-Luc, Amiel, Jeanne, Martinovic, Jelena, Delanne, Julian, Albuisson, Juliette, Lambert, Laëtitia, Perrin, Laurence, Ousager, Lilian Bomme, Van Maldergem, Lionel, Pinson, Lucile, Ruaud, Lyse, Samimi, Mahtab, Bournez, Marie, Bonnet-Dupeyron, Marie Noëlle, Vincent, Marie, Jacquemont, Marie-Line, Cordier-Alex, Marie-Pierre, Gérard-Blanluet, Marion, Willems, Marjolaine, Spodenkiewicz, Marta, Doco-Fenzy, Martine, Rossi, Massimiliano, Renaud, Mathilde, Fradin, Mélanie, Mathieu, Michèle, Holder-Espinasse, Muriel H., Houcinat, Nada, Hanna, Nadine, Leperrier, Nathalie, Chassaing, Nicolas, Philip, Nicole, Boute, Odile, Van Kien, Philippe Khau, Parent, Philippe, Bitoun, Pierre, Sarda, Pierre, Vabres, Pierre, Jouk, Pierre-Simon, Touraine, Renaud, El Chehadeh, Salima, Whalen, Sandra, Marlin, Sandrine, Passemard, Sandrine, Grotto, Sarah, Bellanger, Séverine Audebert, Blesson, Sophie, Nambot, Sophie, Naudion, Sophie, Lyonnet, Stanislas, Odent, Sylvie, Attie-Bitach, Tania, Busa, Tiffany, Drouin-Garraud, Valérie, Layet, Valérie, Bizaoui, Varoona, Cusin, Véronica, Capri, Yline, Alembik, Yves, Jean-Marçais, Nolwenn, López-Martín, Estrella, Macek, Milan, Mencarelli, Maria Antonietta, Moutton, Sébastien, Pfundt, Rolph, Safraou, Hana, Thauvin-Robinet, Christel, Thevenon, Julien, Tran Mau-Them, Frédéric, de Vries, Bert B.A., Willemsen, Marjolein H., and Philippe, Christophe

Published
2023
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225. Epidemiology and management of nontuberculous mycobacterial disease in people with cystic fibrosis, the Netherlands

Author

Akkerman, O.W., Altenburg, J., Bakker, M., Bannier, M.A.G.E., Conemans, L.H., Gulmans, V.A.M., Heijerman, H.G.M., Hoek, R.A.S., Janssens, H.M., van der Meer, R., Merkus, P.J.F.M., Noordhoek, J.J., Nuijsink, M., Terheggen-Lagro, S.W.J., van der Vaart, H., de Winter-de Groot, K.M., Zomer, Domenique, van Ingen, Jakko, and Hofland, Regina

Published
2023
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227. Percutaneous coronary intervention of native coronary artery versus saphenous vein graft in patients with prior coronary artery bypass graft surgery: Rationale and design of the multicenter, randomized PROCTOR trial

Author

de Winter, Ruben W., Walsh, Simon J., Hanratty, Colm G., Spratt, James C., Sprengers, Ralf W., Twisk, Jos W.R., Vegting, Iris, Schumacher, Stefan P., Bom, Michiel J., Hoek, Roel, Verouden, Niels J., Delewi, Ronak, Nap, Alexander, and Knaapen, Paul

Published
2023
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240. Optimally Weighted Ensembles for Efficient Multi-objective Optimization

Author

Hanse, Gideon, de Winter, Roy, van Stein, Bas, Bäck, Thomas, Goos, Gerhard, Founding Editor, Hartmanis, Juris, Founding Editor, Bertino, Elisa, Editorial Board Member, Gao, Wen, Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Woeginger, Gerhard, Editorial Board Member, Yung, Moti, Editorial Board Member, Nicosia, Giuseppe, editor, Ojha, Varun, editor, La Malfa, Emanuele, editor, La Malfa, Gabriele, editor, Jansen, Giorgio, editor, Pardalos, Panos M., editor, Giuffrida, Giovanni, editor, and Umeton, Renato, editor

Published
2022
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241. MoveRL: To a Safer Robotic Reinforcement Learning Environment

Author

Liu, Gaoyuan, De Winter, Joris, Vanderborght, Bram, Nowé, Ann, Steckelmacher, Denis, Filipe, Joaquim, Editorial Board Member, Ghosh, Ashish, Editorial Board Member, Prates, Raquel Oliveira, Editorial Board Member, Zhou, Lizhu, Editorial Board Member, Leiva, Luis A., editor, Pruski, Cédric, editor, Markovich, Réka, editor, Najjar, Amro, editor, and Schommer, Christoph, editor

Published
2022
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249. Risk and determinants of low and very low bone mineral density and fractures in a national cohort of Dutch adult childhood cancer survivors (DCCSS-LATER): a cross-sectional study

Author

van Atteveld, Jenneke E, de Winter, Demi T C, Pluimakers, Vincent G, Fiocco, Marta, Nievelstein, Rutger A J, Hobbelink, Monique G G, de Vries, Andrica C H, Loonen, Jacqueline J, van Dulmen-den Broeder, Eline, van der Pal, Helena J, Pluijm, Saskia M F, Kremer, Leontien C M, Ronckers, Cécile M, van der Heiden-van der Loo, Margriet, Versluijs, A Birgitta, Louwerens, Marloes, Bresters, Dorine, van Santen, Hanneke M, Olsson, Daniel S, Hoefer, Imo, van den Berg, Sjoerd A A, den Hartogh, Jaap, Tissing, Wim J E, Neggers, Sebastian J C M M, and van den Heuvel-Eibrink, Marry M

Published
2023
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250. The mega COMBO collaboration: An individual patient data pooled analysis of patients undergoing PCI with COMBO stent

Author

Nardin, Matteo, Pivato, Carlo Andrea, Cao, Davide, Sartori, Samantha, Zhang, Zhongjie, Vogel, Birgit, Nicolas, Johny, Chiarito, Mauro, Qiu, Hanbo, Chandrasekhar, Jaya, Spirito, Alessandro, Abizaid, Alexandre, Christiansen, Evald Høj, Colombo, Antonio, de Winter, Robbert J., Haude, Michael, Jakobsen, Lars, Jensen, Lisette Okkels, Krucoff, Mitchell W., Landmesser, Ulf, Saito, Shigeru, Suryapranata, Harry, De Luca, Giuseppe, Dangas, George, and Mehran, Roxana

Published
2023
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