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208. Association of HER2DX with pathological complete response and survival outcomes in HER2-positive breast cancer

Author

Villacampa, G., Tung, N.M., Pernas, S., Paré, L., Bueno-Muiño, C., Echavarría, I., López-Tarruella, S., Roche-Molina, M., del Monte-Millán, M., Marín-Aguilera, M., Brasó-Maristany, F., Waks, A.G., Pascual, T., Martínez-Sáez, O., Vivancos, A., Conte, P.F., Guarneri, V., Vittoria Dieci, M., Griguolo, G., Cortés, J., Llombart-Cussac, A., Muñoz, M., Vidal, M., Adamo, B., Wolff, A.C., DeMichele, A., Villagrasa, P., Parker, J.S., Perou, C.M., Fernandez-Martinez, A., Carey, L.A., Mittendorf, E.A., Martín, M., Prat, A., and Tolaney, S.M.

Published
2023
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209. Vela pulsar wind nebula X-rays are polarized to near the synchrotron limit

Author

Xie, Fei, Di Marco, Alessandro, La Monaca, Fabio, Liu, Kuan, Muleri, Fabio, Bucciantini, Niccolò, Romani, Roger W., Costa, Enrico, Rankin, John, Soffitta, Paolo, Bachetti, Matteo, Di Lalla, Niccolò, Fabiani, Sergio, Ferrazzoli, Riccardo, Gunji, Shuichi, Latronico, Luca, Negro, Michela, Omodei, Nicola, Pilia, Maura, Trois, Alessio, Watanabe, Eri, Agudo, Iván, Antonelli, Lucio A., Baldini, Luca, Baumgartner, Wayne H., Bellazzini, Ronaldo, Bianchi, Stefano, Bongiorno, Stephen D., Bonino, Raffaella, Brez, Alessandro, Capitanio, Fiamma, Castellano, Simone, Cavazzuti, Elisabetta, Ciprini, Stefano, De Rosa, Alessandra, Del Monte, Ettore, Di Gesu, Laura, Donnarumma, Immacolata, Doroshenko, Victor, Dovčiak, Michal, Ehlert, Steven R., Enoto, Teruaki, Evangelista, Yuri, Garcia, Javier A., Hayashida, Kiyoshi, Heyl, Jeremy, Iwakiri, Wataru, Jorstad, Svetlana G., Karas, Vladimir, Kitaguchi, Takao, Kolodziejczak, Jeffery J., Krawczynski, Henric, Liodakis, Ioannis, Maldera, Simone, Manfreda, Alberto, Marin, Frédéric, Marinucci, Andrea, Marscher, Alan P., Marshall, Herman L., Massaro, Francesco, Matt, Giorgio, Mitsuishi, Ikuyuki, Mizuno, Tsunefumi, Ng, C.-Y., O’Dell, Stephen L., Oppedisano, Chiara, Papitto, Alessandro, Pavlov, George G., Peirson, Abel L., Perri, Matteo, Pesce-Rollins, Melissa, Petrucci, Pierre-Olivier, Possenti, Andrea, Poutanen, Juri, Puccetti, Simonetta, Ramsey, Brian D., Ratheesh, Ajay, Sgró, Carmelo, Slane, Patrick, Spandre, Gloria, Tamagawa, Toru, Tavecchio, Fabrizio, Taverna, Roberto, Tawara, Yuzuru, Tennant, Allyn F., Thomas, Nicolas E., Tombesi, Francesco, Tsygankov, Sergey S., Turolla, Roberto, Vink, Jacco, Weisskopf, Martin C., Wu, Kinwah, and Zane, Silvia

Published
2022
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210. Test to evaluate the mental representation of technical and dynamic knowledge in pre-established sports actions in taekwondo poomsae/Test para evaluar la representación mental de los conocimientos técnicos y dinámicos en las acciones deportivas preestable

Author

Roberto Fernández Fonseca and Liliana Marìa del Monte del Monte

Subjects
representación mental, taekwondo, test, poomsae., Sports, GV557-1198.995
Abstract

Introduction: At the Cuban Sports Research Center, studies have been carried out to improve the mental representation of poomsae in high sports performance of taekwondo, related to the logical ordering of its technical sequence. However, it is also necessary to assess the dynamic accents of the movement, which are also evaluated in competition. Objective: The objective of this work was to determine, through a test, the level of knowledge of the technical and dynamic component that the athlete possesses in the mental plane of a pre-established exercises complex such as the world taekwondo poomsae Materials and methods: The empirical methods of documentary review and measurement test were used, as well as the theoretical Inductive-deductive and abstraction methods. Likewise, a formula was assumed to determine the effectiveness of the technical and dynamic ordering of the poomsae, as well as the use of statistical procedures of empirical distributions of frequency with percentage distribution. The population was a study of ten taekwondo specialists, of which subject number eight is presented in a case study. Results: Among the fundamental results, omissions of technical order were identified, but also of important dynamic aspects in the internal model of the studied subject that were not previously detected and, now with this proposal, they can be methodologically treated with greater focus to eradicate them. Conclusions: The theoretical referents on the subject of study supported the analyzes and theoretical inferences expressed by the authors about the theoretical feasibility of the test studied, in which a didactic and methodological enrichment of its content and evaluation was appreciated.

Published
2022

211. CARACTERÍZACIÓN DE EXTRACTOS OBTENIDOS A PARTIR DEL MOLUSCO Stylocheilus longicauda (MOLLUSCA: GASTROPODA).

Author

D.L. Romero, C. Fernández, A. del Monte, M. Alonso del Rivero, and J. Delfín

Subjects
actividades enzimáticas, actividades inhibitorias, proteasas, lipasas, Stylocheilus longicauda, Geography. Anthropology. Recreation, Oceanography, GC1-1581
Abstract

En el presente trabajo se describen los resultados obtenidos de la determinación de algunas actividades enzimáticas y actividad inhibidora de ellas en el molusco Stylocheilus longicauda. Se prepararon extractos acuosos de las diferentes partes del animal (hepatopáncreas, manto, gónadas así como un extracto total). Todos los extractos mostraron actividad proteolítica a todos los valores de pH ensayados. Se detectó también en todos, la presencia de actividad inhibidora de pepsina y bromelina, la que fue más notable en el caso del manto para pepsina, así como actividad acetilcolinesterásica para los extractos de manto y total. No se detectó inhibición para acetilcolinesterasa en ninguno de los extractos ensayados. Por otra parte, el extracto total mostró poseer actividad esterásica y lipásica.

Published
2023

212. Quantitative trait and transcriptome analysis of genetic complexity underpinning cardiac interatrial septation in mice using an advanced intercross line

Author

Mahdi Moradi Marjaneh, Edwin P Kirk, Ralph Patrick, Dimuthu Alankarage, David T Humphreys, Gonzalo Del Monte-Nieto, Paola Cornejo-Paramo, Vaibhao Janbandhu, Tram B Doan, Sally L Dunwoodie, Emily S Wong, Chris Moran, Ian CA Martin, Peter C Thomson, and Richard P Harvey

Subjects
quantitative trait loci, genomics, cardiac congenital defects, Medicine, Science, Biology (General), QH301-705.5
Abstract

Unlike single-gene mutations leading to Mendelian conditions, common human diseases are likely to be emergent phenomena arising from multilayer, multiscale, and highly interconnected interactions. Atrial and ventricular septal defects are the most common forms of cardiac congenital anomalies in humans. Atrial septal defects (ASD) show an open communication between the left and right atria postnatally, potentially resulting in serious hemodynamic consequences if untreated. A milder form of atrial septal defect, patent foramen ovale (PFO), exists in about one-quarter of the human population, strongly associated with ischaemic stroke and migraine. The anatomic liabilities and genetic and molecular basis of atrial septal defects remain unclear. Here, we advance our previous analysis of atrial septal variation through quantitative trait locus (QTL) mapping of an advanced intercross line (AIL) established between the inbred QSi5 and 129T2/SvEms mouse strains, that show extremes of septal phenotypes. Analysis resolved 37 unique septal QTL with high overlap between QTL for distinct septal traits and PFO as a binary trait. Whole genome sequencing of parental strains and filtering identified predicted functional variants, including in known human congenital heart disease genes. Transcriptome analysis of developing septa revealed downregulation of networks involving ribosome, nucleosome, mitochondrial, and extracellular matrix biosynthesis in the 129T2/SvEms strain, potentially reflecting an essential role for growth and cellular maturation in septal development. Analysis of variant architecture across different gene features, including enhancers and promoters, provided evidence for the involvement of non-coding as well as protein-coding variants. Our study provides the first high-resolution picture of genetic complexity and network liability underlying common congenital heart disease, with relevance to human ASD and PFO.

Published
2023
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213. When Good Goes Bad∗

Author

Alvise Del Monte, MD, Gian Battista Chierchia, MD, PhD, Carlo de Asmundis, MD, PhD, and Antonio Sorgente, MD, PhD

Subjects
complications, conduction system pacing, interventricular septal hematoma, left bundle branch pacing, septal injuries, Diseases of the circulatory (Cardiovascular) system, RC666-701
Published
2023
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214. Assessing the impact of an antigen-specific antibody response on atherosclerosis development in mice

Author

Alberto Del Monte-Monge, Inmaculada Martos-Folgado, Ana Rodríguez-Ronchel, and Almudena R. Ramiro

Subjects
Flow Cytometry/Mass Cytometry, Immunology, Model Organisms, Antibody, Science (General), Q1-390
Abstract

Summary: The antibody immune response plays a critical role in atherosclerosis. Here, we present a protocol for assessing the impact of an antigen-specific germinal center antibody response on atherosclerosis development, using a pro-atherogenic mouse model deficient for the production of germinal-center-derived antibodies. We describe steps for bone marrow transfer from donor mice into irradiated recipient mice. We then detail immunization of mouse chimeras with atheroprotective malondialdehyde low-density lipoprotein during high-fat diet feeding and atherosclerosis burden analysis.For complete details on the use and execution of this protocol, please refer to Martos-Folgado et al. (2022).1 : Publisher’s note: Undertaking any experimental protocol requires adherence to local institutional guidelines for laboratory safety and ethics.

Published
2023
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215. Myofibroblast senescence promotes arrhythmogenic remodeling in the aged infarcted rabbit heart

Author

Brett C Baggett, Kevin R Murphy, Elif Sengun, Eric Mi, Yueming Cao, Nilufer N Turan, Yichun Lu, Lorraine Schofield, Tae Yun Kim, Anatoli Y Kabakov, Peter Bronk, Zhilin Qu, Patrizia Camelliti, Patrycja Dubielecka, Dmitry Terentyev, Federica del Monte, Bum-Rak Choi, John Sedivy, and Gideon Koren

Subjects
cardiac arrhythmia, sudden cardiac death, myocardial infarction, senescence, Medicine, Science, Biology (General), QH301-705.5
Abstract

Progressive tissue remodeling after myocardial infarction (MI) promotes cardiac arrhythmias. This process is well studied in young animals, but little is known about pro-arrhythmic changes in aged animals. Senescent cells accumulate with age and accelerate age-associated diseases. Senescent cells interfere with cardiac function and outcome post-MI with age, but studies have not been performed in larger animals, and the mechanisms are unknown. Specifically, age-associated changes in timecourse of senescence and related changes in inflammation and fibrosis are not well understood. Additionally, the cellular and systemic role of senescence and its inflammatory milieu in influencing arrhythmogenesis with age is not clear, particularly in large animal models with cardiac electrophysiology more similar to humans than previously studied animal models. Here, we investigated the role of senescence in regulating inflammation, fibrosis, and arrhythmogenesis in young and aged infarcted rabbits. Aged rabbits exhibited increased peri-procedural mortality and arrhythmogenic electrophysiological remodeling at the infarct border zone (IBZ) compared to young rabbits. Studies of the aged infarct zone revealed persistent myofibroblast senescence and increased inflammatory signaling over a 12-week timecourse. Senescent IBZ myofibroblasts in aged rabbits appear to be coupled to myocytes, and our computational modeling showed that senescent myofibroblast-cardiomyocyte coupling prolongs action potential duration (APD) and facilitates conduction block permissive of arrhythmias. Aged infarcted human ventricles show levels of senescence consistent with aged rabbits, and senescent myofibroblasts also couple to IBZ myocytes. Our findings suggest that therapeutic interventions targeting senescent cells may mitigate arrhythmias post-MI with age.

Published
2023
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217. X-ray polarization measurement of the gold standard of radio-quiet active galactic nuclei: NGC 1068

Author

Marin, F., primary, Marinucci, A., additional, Laurenti, M., additional, Kim, D.E., additional, Barnouin, T., additional, Di Marco, A., additional, Ursini, F., additional, Bianchi, S., additional, Ravi, S., additional, Marshall, H.L., additional, Matt, G., additional, Chen, C.-T., additional, Gianolli, V.E., additional, Ingram, A., additional, Middei, R., additional, Maksym, W.P., additional, Panagiotou, C., additional, Podgorny, J., additional, Puccetti, S., additional, Ratheesh, A., additional, Tombesi, F., additional, Agudo, I., additional, Antonelli, L.A., additional, Bachetti, M., additional, Baldini, L., additional, Baumgartner, W., additional, Bellazzini, R., additional, Bongiorno, S., additional, Bonino, R., additional, Brez, A., additional, Bucciantini, N., additional, Capitanio, F., additional, Castellano, S., additional, Cavazzuti, E., additional, Ciprini, S., additional, Costa, E., additional, De Rosa, A., additional, Del Monte, E., additional, Di Gesu, L., additional, Di Lalla, N., additional, Donnarumma, I., additional, Doroshenko, V., additional, Dovčiak, M., additional, Ehlert, S., additional, Enoto, T., additional, Evangelista, Y., additional, Fabiani, S., additional, Ferrazzoli, R., additional, Garcia, J., additional, Gunji, S., additional, Heyl, J., additional, Iwakiri, W., additional, Jorstad, S., additional, Kaaret, P., additional, Karas, V., additional, Kislat, F., additional, Kitaguchi, T., additional, Kolodziejczak, J., additional, Krawczynski, H., additional, La Monaca, F., additional, Latronico, L., additional, Liodakis, I., additional, Madejski, G., additional, Maldera, S., additional, Manfreda, A., additional, Marscher, A., additional, Massaro, F., additional, Mitsuishi, I., additional, Mizuno, T., additional, Muleri, F., additional, Negro, M., additional, Ng, S., additional, O'Dell, S., additional, Omodei, N., additional, Oppedisano, C., additional, Papitto, A., additional, Pavlov, G., additional, Perri, M., additional, Pesce-Rollins, M., additional, Petrucci, P.-O., additional, Pilia, M., additional, Possenti, A., additional, Poutanen, J., additional, Ramsey, B., additional, Rankin, J., additional, Roberts, O., additional, Romani, R., additional, Sgrò, C., additional, Slane, P., additional, Soffitta, P., additional, Spandre, G., additional, Swartz, D., additional, Tamagawa, T., additional, Tavecchio, F., additional, Taverna, R., additional, Tawara, Y., additional, Tennant, A., additional, Thomas, N., additional, Trois, A., additional, Tsygankov, S., additional, Turolla, R., additional, Vink, J., additional, Weisskopf, M., additional, Wu, K., additional, Xie, F., additional, and Zane, S., additional

Published
2024
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218. Data from Tumor-Infiltrating Lymphocytes Refine Outcomes in Triple-Negative Breast Cancer Treated with Anthracycline-Free Neoadjuvant Chemotherapy

Author

Martín, Miguel, primary, Yoder, Rachel, primary, Salgado, Roberto, primary, del Monte-Millán, María, primary, Álvarez, Enrique L., primary, Echavarría, Isabel, primary, Staley, Joshua M., primary, O'Dea, Anne P., primary, Nye, Lauren E., primary, Stecklein, Shane R., primary, Bueno, Coralia, primary, Jerez, Yolanda, primary, Cebollero, María, primary, Bueno, Oscar, primary, García Saenz, José Ángel, primary, Moreno, Fernando, primary, Bohn, Uriel, primary, Gómez, Henry, primary, Massarrah, Tatiana, primary, Khan, Qamar J., primary, Godwin, Andrew K., primary, López-Tarruella, Sara, primary, and Sharma, Priyanka, primary

Published
2024
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220. Real-world multicenter registry on a novel focal lattice tip catheter toggling between pulsed electric field and radiofrequency for atrial tachyarrhythmia ablation

Author

Della Rocca, D, primary, Vetta, G, additional, Mene, R, additional, Pannone, L, additional, Betancur, A, additional, Sorgente, A, additional, Almorad, A, additional, La Meir, M, additional, Del Monte, A, additional, Marcon, L, additional, Combes, S, additional, Boveda, S, additional, De Asmundis, C, additional, Sarkozy, A, additional, and Chierchia, G B, additional

Published
2024
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221. Pulmonary vein isolation with the radiofrequency balloon catheter: long-term results and predictors of ablation success

Author

Del Monte, A, primary, Almorad, A, additional, Della Rocca, D G, additional, Pannone, L, additional, Vetta, G, additional, Cespon Fernandez, M, additional, Doundoulakis, I, additional, Marcon, L, additional, Monaco, C, additional, Bala, G, additional, Stroker, E, additional, Sieira, J, additional, Sarkozy, A, additional, Chierchia, G B, additional, and De Asmundis, C, additional

Published
2024
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222. Cryoballoon ablation for atrial fibrillation in young adults: a propensity-score matching comparison with an older cohort

Author

Cecchini, F, primary, Mugnai, G, additional, Di Vilio, A, additional, Almorad, A, additional, Del Monte, A, additional, Artale, P, additional, Filannino, P, additional, Petretta, A, additional, Colella, J, additional, Statuto, G, additional, Maj, R, additional, Sieira, J, additional, Chierchia, G B, additional, De Asmundis, C, additional, and Iacopino, S, additional

Published
2024
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223. Preventing vagal response during pulmonary vein isolation with pulsed field ablation: impact of the order of the targeted pulmonary veins

Author

Del Monte, A, primary, Della Rocca, D G, additional, Pannone, L, additional, Vetta, G, additional, Cespon Fernandez, M, additional, Doundoulakis, I, additional, Marcon, L, additional, Monaco, C, additional, Bala, G, additional, Stroker, E, additional, Sieira, J, additional, Almorad, A, additional, Sarkozy, A, additional, Chierchia, G B, additional, and De Asmundis, C, additional

Published
2024
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224. Multielectrode catheter-based pulsed field ablation of persistent and long-standing persistent atrial fibrillation

Author

Della Rocca, D, primary, Sorgente, A, additional, Pannone, L, additional, Stroker, E, additional, Vetta, G, additional, Doundoulakis, I, additional, Del Monte, A, additional, Mouram, S, additional, Mene, R, additional, Betancur, A, additional, Boveda, S, additional, Natale, A, additional, Sarkozy, A, additional, De Asmundis, C, additional, and Chierchia, G B, additional

Published
2024
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225. First multicenter experience of pulmonary vein and posterior wall isolation via a novel focal 9mm lattice tip catheter in a real-world scenario

Author

Vetta, G, primary, Della Rocca, D G, additional, Pannone, L, additional, Sorgente, A, additional, Cespon-Fernandez, M, additional, Del Monte, A, additional, Mene, R, additional, Almorad, A, additional, Sieira, J, additional, Bala, G, additional, Stroker, E, additional, Boveda, S, additional, Sarkozy, A, additional, De Asmundis, C, additional, and Chierchia, G B, additional

Published
2024
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226. Predictors of neuromodulation during single-shot thermal atrial fibrillation ablation: a computed tomography imaging analysis

Author

Nakasone, K, primary, Del Monte, A, additional, Della Rocca, D G, additional, Pannone, L, additional, Gauthey, A, additional, Overeinder, I, additional, Bala, G, additional, Sorgente, A, additional, Sieira, J, additional, Almorad, A, additional, Sarkozy, A, additional, Chierchia, G B, additional, De Asmundis, C, additional, Tanaka, K, additional, and Stroker, E, additional

Published
2024
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227. First experience of focal pulsed field ablation for premature ventricular contractions

Author

Cespon Fernandez, M, primary, Della Rocca, D G, additional, Almorad, A, additional, Vetta, G, additional, Del Monte, A, additional, Pannone, L, additional, Mouram, S, additional, Sorgente, A, additional, Sieira, J, additional, Stroker, E, additional, Bala, G, additional, Overeinder, I, additional, Chierchia, G B, additional, De Asmundis, C, additional, and Sakorzy, A, additional

Published
2024
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228. Procedural characteristics, details on epicardial mapping-based lesion transmurality, and long-term success of posterior wall isolation with a pentaspline pulsed field ablation device

Author

Della Rocca, D, primary, Cespon-Fernandez, M, additional, Glowniak, A, additional, Sousonis, V, additional, Vetta, G, additional, Magnocavallo, M, additional, Pannone, L, additional, Sorgente, A, additional, Mene, R, additional, Del Monte, A, additional, Sarkozy, A, additional, Boveda, S, additional, Natale, A, additional, De Asmundis, C, additional, and Chierchia, G B, additional

Published
2024
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229. Prophylactic administration of glycopyrrolate prevents vasovagal responses induced by pulsed field ablation in patients with atrial fibrillation

Author

Vetta, G, primary, Della Rocca, D G, additional, Cespon-Fernandez, M, additional, Del Monte, A, additional, Magnocavallo, M, additional, Mene, R, additional, Pannone, L, additional, Sorgente, A, additional, Sieira, J, additional, Stroker, E, additional, Rossi, P, additional, Boveda, S, additional, Sarkozy, A, additional, De Asmundis, C, additional, and Chierchia, G B, additional

Published
2024
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231. X-Ray and Multiwavelength Polarization of Mrk 501 from 2022 to 2023

Author

Chien-Ting J. Chen, Ioannis Liodakis, Riccardo Middei, Dawoon E. Kim, Laura Di Gesu, Alessandro Di Marco, Steven R. Ehlert, Manel Errando, Michela Negro, Svetlana G. Jorstad, Alan P. Marscher, Kinwah Wu, Iván Agudo, Juri Poutanen, Tsunefumi Mizuno, Pouya M. Kouch, Elina Lindfors, George A. Borman, Tatiana S. Grishina, Evgenia N. Kopatskaya, Elena G. Larionova, Daria A. Morozova, Sergey S. Savchenko, Ivan S. Troitsky, Yulia V. Troitskaya, Andrey A. Vasilyev, Alexey V. Zhovtan, Francisco José Aceituno, Giacomo Bonnoli, Víctor Casanova, Juan Escudero, Beatriz Agís-González, César Husillos, Jorge Otero Santos, Alfredo Sota, Vilppu Piirola, Ioannis Myserlis, Emmanouil Angelakis, Alexander Kraus, Mark Gurwell, Garrett Keating, Ramprasad Rao, Sincheol Kang, Sang-Sung Lee, Sang-Hyun Kim, Whee Yeon Cheong, Hyeon-Woo Jeong, Chanwoo Song, Andrei V. Berdyugin, Masato Kagitani, Vadim Kravtsov, Anagha P. Nitindala, Takeshi Sakanoi, Ryo Imazawa, Mahito Sasada, Yasushi Fukazawa, Koji S. Kawabata, Makoto Uemura, Tatsuya Nakaoka, Hiroshi Akitaya, Carolina Casadio, Albrecht Sievers, Lucio Angelo Antonelli, Matteo Bachetti, Luca Baldini, Wayne H. Baumgartner, Ronaldo Bellazzini, Stefano Bianchi, Stephen D. Bongiorno, Raffaella Bonino, Alessandro Brez, Niccoló Bucciantini, Fiamma Capitanio, Simone Castellano, Elisabetta Cavazzuti, Stefano Ciprini, Enrico Costa, Alessandra De Rosa, Ettore Del Monte, Niccoló Di Lalla, Immacolata Donnarumma, Victor Doroshenko, Michal Dovčiak, Teruaki Enoto, Yuri Evangelista, Sergio Fabiani, Riccardo Ferrazzoli, Javier A. Garcia, Shuichi Gunji, Kiyoshi Hayashida, Jeremy Heyl, Wataru Iwakiri, Philip Kaaret, Vladimir Karas, Fabian Kislat, Takao Kitaguchi, Jeffery J. Kolodziejczak, Henric Krawczynski, Fabio La Monaca, Luca Latronico, Simone Maldera, Alberto Manfreda, Frédéric Marin, Andrea Marinucci, Herman L. Marshall, Francesco Massaro, Giorgio Matt, Ikuyuki Mitsuishi, Fabio Muleri, C.-Y. Ng, Stephen L. O’Dell, Nicola Omodei, Chiara Oppedisano, Alessandro Papitto, George G. Pavlov, Abel Lawrence Peirson, Matteo Perri, Melissa Pesce-Rollins, Pierre-Olivier Petrucci, Maura Pilia, Andrea Possenti, Simonetta Puccetti, Brian D. Ramsey, John Rankin, Ajay Ratheesh, Oliver J. Roberts, Roger W. Romani, Carmelo Sgró, Patrick Slane, Paolo Soffitta, Gloria Spandre, Douglas A. Swartz, Toru Tamagawa, Fabrizio Tavecchio, Roberto Taverna, Yuzuru Tawara, Allyn F. Tennant, Nicholas E. Thomas, Francesco Tombesi, Alessio Trois, Sergey S. Tsygankov, Roberto Turolla, Jacco Vink, Martin C. Weisskopf, Fei Xie, and Silvia Zane

Subjects
Blazars, Active galaxies, Black holes, Relativistic jets, Spectropolarimetry, Polarimetry, Astrophysics, QB460-466
Abstract

We present multiwavelength polarization measurements of the luminous blazar Mrk 501 over a 14 month period. The 2–8 keV X-ray polarization was measured with the Imaging X-ray Polarimetry Explorer (IXPE) with six 100 ks observations spanning from 2022 March to 2023 April. Each IXPE observation was accompanied by simultaneous X-ray data from NuSTAR, Swift/XRT, and/or XMM-Newton. Complementary optical–infrared polarization measurements were also available in the B , V , R , I , and J bands, as were radio polarization measurements from 4.85 GHz to 225.5 GHz. Among the first five IXPE observations, we did not find significant variability in the X-ray polarization degree and angle with IXPE. However, the most recent sixth observation found an elevated polarization degree at >3 σ above the average of the other five observations. The optical and radio measurements show no apparent correlations with the X-ray polarization properties. Throughout the six IXPE observations, the X-ray polarization degree remained higher than, or similar to, the R -band optical polarization degree, which remained higher than the radio value. This is consistent with the energy-stratified shock scenario proposed to explain the first two IXPE observations, in which the polarized X-ray, optical, and radio emission arises from different regions.

Published
2024
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232. Analysis of Crab X-Ray Polarization Using Deeper Imaging X-Ray Polarimetry Explorer Observations

Author

Josephine Wong, Tsunefumi Mizuno, Niccoló Bucciantini, Roger W. Romani, Yi-Jung Yang, Kuan Liu, Wei Deng, Kazuho Goya, Fei Xie, Maura Pilia, Philip Kaaret, Martin C. Weisskopf, Stefano Silvestri, C.-Y. Ng, Chien-Ting Chen, Iván Agudo, Lucio A. Antonelli, Matteo Bachetti, Luca Baldini, Wayne H. Baumgartner, Ronaldo Bellazzini, Stefano Bianchi, Stephen D. Bongiorno, Raffaella Bonino, Alessandro Brez, Fiamma Capitanio, Simone Castellano, Elisabetta Cavazzuti, Stefano Ciprini, Enrico Costa, Alessandra De Rosa, Ettore Del Monte, Laura Di Gesu, Niccoló Di Lalla, Alessandro Di Marco, Immacolata Donnarumma, Victor Doroshenko, Michal Dovčiak, Steven R. Ehlert, Teruaki Enoto, Yuri Evangelista, Sergio Fabiani, Riccardo Ferrazzoli, Javier A. Garcia, Shuichi Gunji, Jeremy Heyl, Wataru Iwakiri, Svetlana G. Jorstad, Vladimir Karas, Fabian Kislat, Takao Kitaguchi, Jeffery J. Kolodziejczak, Henric Krawczynski, Fabio La Monaca, Luca Latronico, Ioannis Liodakis, Simone Maldera, Alberto Manfreda, Frédéric Marin, Andrea Marinucci, Alan P. Marscher, Herman L. Marshall, Francesco Massaro, Giorgio Matt, Ikuyuki Mitsuishi, Fabio Muleri, Michela Negro, Stephen L. O’Dell, Nicola Omodei, Chiara Oppedisano, Alessandro Papitto, George G. Pavlov, Abel Lawrence Peirson, Matteo Perri, Melissa Pesce-Rollins, Pierre-Olivier Petrucci, Andrea Possenti, Juri Poutanen, Simonetta Puccetti, Brian D. Ramsey, John Rankin, Ajay Ratheesh, Oliver J. Roberts, Carmelo Sgró, Patrick Slane, Paolo Soffitta, Gloria Spandre, Douglas A. Swartz, Toru Tamagawa, Fabrizio Tavecchio, Roberto Taverna, Yuzuru Tawara, Allyn F. Tennant, Nicholas E. Thomas, Francesco Tombesi, Alessio Trois, Sergey Tsygankov, Roberto Turolla, Jacco Vink, Kinwah Wu, and Silvia Zane

Subjects
Pulsar wind nebulae, Pulsars, Polarimetry, X-ray astronomy, Astrophysics, QB460-466
Abstract

We present Crab X-ray polarization measurements using Imaging X-Ray Polarimetry Explorer (IXPE) data with a total exposure of 300 ks, three times more than the initial 2022 discovery paper. Polarization is detected in three times more pulsar phase bins, revealing an S-shaped +40° polarization angle sweep in the main pulse and >1 σ departures from the OPTIMA optical polarization in both pulses, suggesting different radiation mechanisms or sites for the polarized emission at the two wavebands. Our polarization map of the inner nebula reveals a toroidal magnetic field, as seen in prior IXPE analyses. Along the southern jet, the magnetic field orientation relative to the jet axis changes from perpendicular to parallel and the polarization degree decreases by ∼6%. These observations may be explained by kink instabilities along the jet or a collision with a dense, jet-deflecting medium at the tip. Using spectropolarimetric analysis, we find asymmetric polarization in the four quadrants of the inner nebula, as expected for a toroidal field geometry, and a spatial correlation between polarization degree and photon index.

Published
2024
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233. Observations of Low and Intermediate Spectral Peak Blazars with the Imaging X-Ray Polarimetry Explorer

Author

Herman L. Marshall, Ioannis Liodakis, Alan P. Marscher, Niccolò Di Lalla, Svetlana G. Jorstad, Dawoon E. Kim, Riccardo Middei, Michela Negro, Nicola Omodei, Abel L. Peirson, Matteo Perri, Simonetta Puccetti, Marco Laurenti, Iván Agudo, Giacomo Bonnoli, Andrei V. Berdyugin, Elisabetta Cavazzuti, Nicole Rodriguez Cavero, Immacolata Donnarumma, Laura Di Gesu, Jenni Jormanainen, Henric Krawczynski, Elina Lindfors, Greg Madjeski, Frédéric Marin, Francesco Massaro, Luigi Pacciani, Juri Poutanen, Fabrizio Tavecchio, Pouya M. Kouch, Francisco José Aceituno, Maria I. Bernardos, Víctor Casanova, Maya García-Comas, Beatriz Agís-González, César Husillos, Alessandro Marchini, Alfredo Sota, Dmitry Blinov, Ioakeim G. Bourbah, Sebastian Kielhmann, Evangelos Kontopodis, Nikos Mandarakas, Stylianos Romanopoulos, Raphael Skalidis, Anna Vervelaki, George A. Borman, Evgenia N. Kopatskaya, Elena G. Larionova, Daria A. Morozova, Sergey S. Savchenko, Andrey A. Vasilyev, Alexey V. Zhovtan, Carolina Casadio, Juan Escudero, Joana Kramer, Ioannis Myserlis, Efthalia Trainou, Ryo Imazawa, Mahito Sasada, Yasushi Fukazawa, Koji S. Kawabata, Makoto Uemura, Tsunefumi Mizuno, Tatsuya Nakaoka, Hiroshi Akitaya, Joseph R. Masiero, Dimitri Mawet, Georgia V. Panopoulou, Samaporn Tinyanont, Masato Kagitani, Vadim Kravtsov, Takeshi Sakanoi, Matthew Dattolo, Mark Gurwell, Garrett Keating, Ramprasad Rao, Whee Yeon Cheong, Hyeon-Woo Jeong, Sincheol Kang, Sang-Hyun Kim, Sang-Sung Lee, Emmanouil Angelakis, Alexander Kraus, Antonio Hales, Seiji Kameno, Ruediger Kneissl, Hugo Messias, Hiroshi Nagai, Lucio A. Antonelli, Matteo Bachetti, Luca Baldini, Wayne H. Baumgartner, Ronaldo Bellazzini, Stefano Bianchi, Stephen D. Bongiorno, Raffaella Bonino, Alessandro Brez, Niccolò Bucciantini, Fiamma Capitanio, Simone Castellano, Chen-Ting Chen, Stefano Ciprini, Enrico Costa, Alessandra De Rosa, Ettore Del Monte, Alessandro Di Marco, Victor Doroshenko, Michal Dovčiak, Steven R. Ehlert, Teruaki Enoto, Yuri Evangelista, Sergio Fabiani, Riccardo Ferrazzoli, Javier A. Garcia, Shuichi Gunji, Kiyoshi Hayashida, Jeremy Heyl, Wataru Iwakiri, Philip Kaaret, Vladimir Karas, Fabian Kislat, Takao Kitaguchi, Jeffery J. Kolodziejczak, Fabio La Monaca, Luca Latronico, Simone Maldera, Alberto Manfreda, Andrea Marinucci, Giorgio Matt, Ikuyuki Mitsuishi, Fabio Muleri, C.-Y. Ng, Stephen L. O’Dell, Chiara Oppedisano, Alessandro Papitto, George G. Pavlov, Melissa Pesce-Rollins, Pierre-Olivier Petrucci, Maura Pilia, Andrea Possenti, Brian D. Ramsey, John Rankin, Ajay Ratheesh, Oliver J. Roberts, Roger W. Romani, Carmelo Sgrò, Patrick Slane, Paolo Soffitta, Gloria Spandre, Douglas A. Swartz, Toru Tamagawa, Roberto Taverna, Yuzuru Tawara, Allyn F. Tennant, Nicholas E. Thomas, Francesco Tombesi, Alessio Trois, Sergey S. Tsygankov, Roberto Turolla, Jacco Vink, Martin C. Weisskopf, Kinwah Wu, Fei Xie, and Silvia Zane

Subjects
X-ray astronomy, Polarimetry, Spectropolarimetry, Radio loud quasars, X-ray quasars, Blazars, Astrophysics, QB460-466
Abstract

We present X-ray polarimetry observations from the Imaging X-ray Polarimetry Explorer (IXPE) of three low spectral peak and one intermediate spectral peak blazars, namely 3C 273, 3C 279, 3C 454.3, and S5 0716+714. For none of these objects was IXPE able to detect X-ray polarization at the 3 σ level. However, we placed upper limits on the polarization degree at ∼10%–30%. The undetected polarizations favor models where the X-ray band is dominated by unpolarized photons upscattered by relativistic electrons in the jets of blazars, although hadronic models are not completely eliminated. We discuss the X-ray polarization upper limits in the context of our contemporaneous multiwavelength polarization campaigns.

Published
2024
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234. Tracking the X-Ray Polarization of the Black Hole Transient Swift J1727.8–1613 during a State Transition

Author

Adam Ingram, Niek Bollemeijer, Alexandra Veledina, Michal Dovčiak, Juri Poutanen, Elise Egron, Thomas D. Russell, Sergei A. Trushkin, Michela Negro, Ajay Ratheesh, Fiamma Capitanio, Riley Connors, Joseph Neilsen, Alexander Kraus, Maria Noemi Iacolina, Alberto Pellizzoni, Maura Pilia, Francesco Carotenuto, Giorgio Matt, Guglielmo Mastroserio, Philip Kaaret, Stefano Bianchi, Javier A. García, Matteo Bachetti, Kinwah Wu, Enrico Costa, Melissa Ewing, Vadim Kravtsov, Henric Krawczynski, Vladislav Loktev, Andrea Marinucci, Lorenzo Marra, Romana Mikušincová, Edward Nathan, Maxime Parra, Pierre-Olivier Petrucci, Simona Righini, Paolo Soffitta, James F. Steiner, Jiří Svoboda, Francesco Tombesi, Stefano Tugliani, Francesco Ursini, Yi-Jung Yang, Silvia Zane, Wenda Zhang, Iván Agudo, Lucio A. Antonelli, Luca Baldini, Wayne H. Baumgartner, Ronaldo Bellazzini, Stephen D. Bongiorno, Raffaella Bonino, Alessandro Brez, Niccolò Bucciantini, Simone Castellano, Elisabetta Cavazzuti, Chien-Ting Chen, Stefano Ciprini, Alessandra De Rosa, Ettore Del Monte, Laura Di Gesu, Niccolò Di Lalla, Alessandro Di Marco, Immacolata Donnarumma, Victor Doroshenko, Steven R. Ehlert, Teruaki Enoto, Yuri Evangelista, Sergio Fabiani, Riccardo Ferrazzoli, Shuichi Gunji, Kiyoshi Hayashida, Jeremy Heyl, Wataru Iwakiri, Svetlana G. Jorstad, Vladimir Karas, Fabian Kislat, Takao Kitaguchi, Jeffery J. Kolodziejczak, Fabio La Monaca, Luca Latronico, Ioannis Liodakis, Simone Maldera, Alberto Manfreda, Frédéric Marin, Alan P. Marscher, Herman L. Marshall, Francesco Massaro, Ikuyuki Mitsuishi, Tsunefumi Mizuno, Fabio Muleri, Chi-Yung Ng, Stephen L. O’Dell, Nicola Omodei, Chiara Oppedisano, Alessandro Papitto, George G. Pavlov, Abel L. Peirson, Matteo Perri, Melissa Pesce-Rollins, Andrea Possenti, Simonetta Puccetti, Brian D. Ramsey, John Rankin, Oliver J. Roberts, Roger W. Romani, Carmelo Sgrò, Patrick Slane, Gloria Spandre, Douglas A. Swartz, Toru Tamagawa, Fabrizio Tavecchio, Roberto Taverna, Yuzuru Tawara, Allyn F. Tennant, Nicholas E. Thomas, Alessio Trois, Sergey S. Tsygankov, Roberto Turolla, Jacco Vink, Martin C. Weisskopf, Fei Xie, and IXPE Collaboration

Subjects
Accretion, X-ray astronomy, Low-mass x-ray binary stars, Polarimetry, Astrophysical black holes, Astrophysics, QB460-466
Abstract

We report on an observational campaign on the bright black hole (BH) X-ray binary Swift J1727.8–1613 centered around five observations by the Imaging X-ray Polarimetry Explorer. These observations track for the first time the evolution of the X-ray polarization of a BH X-ray binary across a hard to soft state transition. The 2–8 keV polarization degree decreased from ∼4% to ∼3% across the five observations, but the polarization angle remained oriented in the north–south direction throughout. Based on observations with the Australia Telescope Compact Array, we find that the intrinsic 7.25 GHz radio polarization aligns with the X-ray polarization. Assuming the radio polarization aligns with the jet direction (which can be tested in the future with higher-spatial-resolution images of the jet), our results imply that the X-ray corona is extended in the disk plane, rather than along the jet axis, for the entire hard intermediate state. This in turn implies that the long (≳10 ms) soft lags that we measure with the Neutron star Interior Composition ExploreR are dominated by processes other than pure light-crossing delays. Moreover, we find that the evolution of the soft lag amplitude with spectral state does not follow the trend seen for other sources, implying that Swift J1727.8–1613 is a member of a hitherto undersampled subpopulation.

Published
2024
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235. Enhancing data integrity and resilience: Extending the CERN backup system with a tape-based backend

Author

Del Monte Gianmaria, Labrador Gonzalez Hugo, Rademakers Fons, and Valverde Roberto

Subjects
Physics, QC1-999
Abstract

The CERN IT Department is responsible for ensuring the integrity and security of data stored in the IT Storage Services. General storage backends such as EOS, CERNBox and CephFS are used to store data for a wide range of use cases for all stakeholders at CERN, including experiment project spaces and user home directories. In recent years a backup system, cback, was developed based on the open source backup program restic. cback is currently used to backup about 2.5 billion files and 18PB stored on disks in the CERN Computing Center. To significantly increase the reliability and security of the backups and reduce the storage costs, by limiting the amount of data on disk, we have added a tape storage backend to cback. With this addition cback can reliably be extended to new use cases, like backing up any local mountable file system, such as EOS, CephFS, NFS or DFS. In this paper we will describe the architecture and implementation of cback with the new tape storage backend and a number of developments planned for the near future.

Published
2024
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236. CERNBox: Storage gateway for CERN and beyond

Author

Gonzalez Labrador Hugo, Del Monte Gianmaria, Ferrer Javier, and Keeble Oliver

Subjects
Physics, QC1-999
Abstract

The CERN IT Storage group ensures the coherent design, development, operation and evolution of storage and data management services at CERN for all aspects of physics, user and project data and general needs of the Laboratory. CERNBox is one of the services that actively contributes to this objective. CERNBox is a cloud collaboration platform providing storage space (18PB) to users (37K accounts), projects (1.1K) and to LHC experiments (ATLAS, CMS, LHCb, ALICE) and other smaller experiments (33). We present the evolution of the platform from its humble origins 10 years ago and how the HEP landscape has influenced the expansion of the service to continue satisfying the ever growing demand of our users. We describe the challenges and opportunities presented by integrating a sync and share solution (ownCloud) with CERN’s custodial storage solution (EOS) and how this stack boosted a coherent integration with analysis farms (LXBATCH), Linux (LXPLUS) and Windows (TS) interactive clusters and Web analysis facilities (SWAN). We then turn to the part CERNBox has played in consolidation efforts in the IT department (DFS, AFS) and in providing end-users with a portfolio of applications (ROOT, CAD, MS365) while guaranteeing a maximum level of privacy. We conclude by presenting the future of the service with its heterogeneous storage federation capabilities (EOSHOMEs, EOSPROJECTs, EOSATLAS, CEPHFS) and WLCG transfer mechanisms (WebDAV TPC).

Published
2024
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237. X-Ray Polarization of the Black Hole X-Ray Binary 4U 1630–47 Challenges the Standard Thin Accretion Disk Scenario

Author

Ajay Ratheesh, Michal Dovčiak, Henric Krawczynski, Jakub Podgorný, Lorenzo Marra, Alexandra Veledina, Valery F. Suleimanov, Nicole Rodriguez Cavero, James F. Steiner, Jiří Svoboda, Andrea Marinucci, Stefano Bianchi, Michela Negro, Giorgio Matt, Francesco Tombesi, Juri Poutanen, Adam Ingram, Roberto Taverna, Andrew West, Vladimir Karas, Francesco Ursini, Paolo Soffitta, Fiamma Capitanio, Domenico Viscolo, Alberto Manfreda, Fabio Muleri, Maxime Parra, Banafsheh Beheshtipour, Sohee Chun, Nicolò Cibrario, Niccolò Di Lalla, Sergio Fabiani, Kun Hu, Philip Kaaret, Vladislav Loktev, Romana Mikušincová, Tsunefumi Mizuno, Nicola Omodei, Pierre-Olivier Petrucci, Simonetta Puccetti, John Rankin, Silvia Zane, Sixuan Zhang, Iván Agudo, Lucio A. Antonelli, Matteo Bachetti, Luca Baldini, Wayne H. Baumgartner, Ronaldo Bellazzini, Stephen D. Bongiorno, Raffaella Bonino, Alessandro Brez, Niccolò Bucciantini, Simone Castellano, Elisabetta Cavazzuti, Chien-Ting Chen, Stefano Ciprini, Enrico Costa, Alessandra De Rosa, Ettore Del Monte, Laura Di Gesu, Alessandro Di Marco, Immacolata Donnarumma, Victor Doroshenko, Steven R. Ehlert, Teruaki Enoto, Yuri Evangelista, Riccardo Ferrazzoli, Javier A. Garcia, Shuichi Gunji, Kiyoshi Hayashida, Jeremy Heyl, Wataru Iwakiri, Svetlana G. Jorstad, Fabian Kislat, Takao Kitaguchi, Jeffery J. Kolodziejczak, Fabio La Monaca, Luca Latronico, Ioannis Liodakis, Simone Maldera, Frédéric Marin, Alan P. Marscher, Herman L. Marshall, Francesco Massaro, Ikuyuki Mitsuishi, Stephen C.-Y. Ng, Stephen L. O’Dell, Chiara Oppedisano, Alessandro Papitto, George G. Pavlov, Abel L. Peirson, Matteo Perri, Melissa Pesce-Rollins, Maura Pilia, Andrea Possenti, Brian D. Ramsey, Oliver J. Roberts, Roger W. Romani, Carmelo Sgrò, Patrick Slane, Gloria Spandre, Douglas A. Swartz, Toru Tamagawa, Fabrizio Tavecchio, Yuzuru Tawara, Allyn F. Tennant, Nicholas E. Thomas, Alessio Trois, Sergey S. Tsygankov, Roberto Turolla, Jacco Vink, Martin C. Weisskopf, Kinwah Wu, and Fei Xie

Subjects
Polarimetry, X-ray astronomy, Stellar mass black holes, Accretion, Astrophysics, QB460-466
Abstract

A large energy-dependent X-ray polarization degree is detected by the Imaging X-ray Polarimetry Explorer (IXPE) in the high-soft emission state of the black hole X-ray binary 4U 1630–47. The highly significant detection (at ≈50 σ confidence level) of an unexpectedly high polarization, rising from ∼6% at 2 keV to ∼10% at 8 keV, cannot be easily reconciled with standard models of thin accretion disks. In this work, we compare the predictions of different theoretical models with the IXPE data and conclude that the observed polarization properties are compatible with a scenario in which matter accretes onto the black hole through a thin disk covered by a partially ionized atmosphere flowing away at mildly relativistic velocities.

Published
2024
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238. X-Ray Polarimetry of the Dipping Accreting Neutron Star 4U 1624–49

Author

M. Lynne Saade, Philip Kaaret, Andrea Gnarini, Juri Poutanen, Francesco Ursini, Stefano Bianchi, Anna Bobrikova, Fabio La Monaca, Alessandro Di Marco, Fiamma Capitanio, Alexandra Veledina, Iván Agudo, Lucio A. Antonelli, Matteo Bachetti, Luca Baldini, Wayne H. Baumgartner, Ronaldo Bellazzini, Stephen D. Bongiorno, Raffaella Bonino, Alessandro Brez, Niccolò Bucciantini, Simone Castellano, Elisabetta Cavazzuti, Chien-Ting Chen, Stefano Ciprini, Enrico Costa, Alessandra De Rosa, Ettore Del Monte, Laura Di Gesu, Niccolò Di Lalla, Immacolata Donnarumma, Victor Doroshenko, Michal Dovčiak, Steven R. Ehlert, Teruaki Enoto, Yuri Evangelista, Sergio Fabiani, Riccardo Ferrazzoli, Javier A. García, Shuichi Gunji, Kiyoshi Hayashida, Jeremy Heyl, Wataru Iwakiri, Svetlana G. Jorstad, Vladimir Karas, Fabian Kislat, Takao Kitaguchi, Jeffery J. Kolodziejczak, Henric Krawczynski, Luca Latronico, Ioannis Liodakis, Simone Maldera, Alberto Manfreda, Frédéric Marin, Andrea Marinucci, Alan P. Marscher, Herman L. Marshall, Francesco Massaro, Giorgio Matt, Ikuyuki Mitsuishi, Tsunefumi Mizuno, Fabio Muleri, Michela Negro, Chi-Yung Ng, Stephen L. O’Dell, Nicola Omodei, Chiara Oppedisano, Alessandro Papitto, George G. Pavlov, Abel L. Peirson, Matteo Perri, Melissa Pesce-Rollins, Pierre-Olivier Petrucci, Maura Pilia, Andrea Possenti, Simonetta Puccetti, Brian D. Ramsey, John Rankin, Ajay Ratheesh, Oliver J. Roberts, Roger W. Romani, Carmelo Sgrò, Patrick Slane, Paolo Soffitta, Gloria Spandre, Douglas A. Swartz, Toru Tamagawa, Fabrizio Tavecchio, Roberto Taverna, Yuzuru Tawara, Allyn F. Tennant, Nicholas E. Thomas, Francesco Tombesi, Alessio Trois, Sergey S. Tsygankov, Roberto Turolla, Jacco Vink, Martin C. Weisskopf, Kinwah Wu, Fei Xie, and Silvia Zane

Subjects
X-ray binary stars, Neutron stars, X-ray astronomy, Polarimetry, Astrophysics, QB460-466
Abstract

We present the first X-ray polarimetric study of the dipping accreting neutron star 4U 1624−49 with the Imaging X-ray Polarimetry Explorer. We report a detection of polarization in the nondip time intervals with a confidence level of 99.99%. We find an average polarization degree (PD) of 3.1% ± 0.7% and a polarization angle of 81° ± 6° east of north in the 2–8 keV band. We report an upper limit on the PD of 22% during the X-ray dips with 95% confidence. The PD increases with energy, reaching from 3.0% ± 0.9% in the 4–6 keV band to 6% ± 2% in the 6–8 keV band. This indicates the polarization likely arises from Comptonization. The high PD observed is unlikely to be produced by Comptonization in the boundary layer or spreading layer alone. It can be produced by the addition of an extended geometrically thin slab corona covering part of the accretion disk, as assumed in previous models of dippers, and/or a reflection component from the accretion disk.

Published
2024
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239. Detection of X-Ray Polarization from the Blazar 1ES 1959+650 with the Imaging X-Ray Polarimetry Explorer

Author

Manel Errando, Ioannis Liodakis, Alan P. Marscher, Herman L. Marshall, Riccardo Middei, Michela Negro, Abel Lawrence Peirson, Matteo Perri, Simonetta Puccetti, Pazit L. Rabinowitz, Iván Agudo, Svetlana G. Jorstad, Sergey S. Savchenko, Dmitry Blinov, Ioakeim G. Bourbah, Sebastian Kiehlmann, Evangelos Kontopodis, Nikos Mandarakas, Stylianos Romanopoulos, Raphael Skalidis, Anna Vervelaki, Francisco José Aceituno, Maria I. Bernardos, Giacomo Bonnoli, Víctor Casanova, Beatriz Agís-González, César Husillos, Alessandro Marchini, Alfredo Sota, Pouya M. Kouch, Elina Lindfors, Carolina Casadio, Juan Escudero, Ioannis Myserlis, Ryo Imazawa, Mahito Sasada, Yasushi Fukazawa, Koji S. Kawabata, Makoto Uemura, Tsunefumi Mizuno, Tatsuya Nakaoka, Hiroshi Akitaya, Mark Gurwell, Garrett K. Keating, Ramprasad Rao, Adam Ingram, Francesco Massaro, Lucio Angelo Antonelli, Raffaella Bonino, Elisabetta Cavazzuti, Chien-Ting Chen, Nicolò Cibrario, Stefano Ciprini, Alessandra De Rosa, Laura Di Gesu, Federico Di Pierro, Immacolata Donnarumma, Steven R. Ehlert, Francesco Fenu, Ephraim Gau, Vladimir Karas, Dawoon E. Kim, Henric Krawczynski, Marco Laurenti, Lindsey Lisalda, Rubén López-Coto, Grzegorz Madejski, Frédéric Marin, Andrea Marinucci, Ikuyuki Mitsuishi, Fabio Muleri, Luigi Pacciani, Alessandro Paggi, Pierre-Olivier Petrucci, Nicole Rodriguez Cavero, Roger W. Romani, Fabrizio Tavecchio, Stefano Tugliani, Kinwah Wu, Matteo Bachetti, Luca Baldini, Wayne H. Baumgartner, Ronaldo Bellazzini, Stefano Bianchi, Stephen D. Bongiorno, Alessandro Brez, Niccolò Bucciantini, Fiamma Capitanio, Simone Castellano, Enrico Costa, Ettore Del Monte, Niccolò Di Lalla, Alessandro Di Marco, Victor Doroshenko, Michal Dovčiak, Teruaki Enoto, Yuri Evangelista, Sergio Fabiani, Riccardo Ferrazzoli, Javier A. Garcia, Shuichi Gunji, Kiyoshi Hayashida, Jeremy Heyl, Wataru Iwakiri, Philip Kaaret, Fabian Kislat, Takao Kitaguchi, Jeffery J. Kolodziejczak, Fabio La Monaca, Luca Latronico, Simone Maldera, Alberto Manfreda, Giorgio Matt, C.-Y. Ng, Stephen L. O’Dell, Nicola Omodei, Chiara Oppedisano, Alessandro Papitto, George G. Pavlov, Melissa Pesce-Rollins, Maura Pilia, Andrea Possenti, Juri Poutanen, Brian D. Ramsey, John Rankin, Ajay Ratheesh, Oliver J. Roberts, Carmelo Sgrò, Patrick Slane, Paolo Soffitta, Gloria Spandre, Douglas A. Swartz, Toru Tamagawa, Roberto Taverna, Yuzuru Tawara, Allyn F. Tennant, Nicholas E. Thomas, Francesco Tombesi, Alessio Trois, Sergey S. Tsygankov, Roberto Turolla, Jacco Vink, Martin C. Weisskopf, Fei Xie, and Silvia Zane

Subjects
Relativistic jets, X-ray active galactic nuclei, Active galactic nuclei, Blazars, Polarimetry, Spectropolarimetry, Astrophysics, QB460-466
Abstract

Observations of linear polarization in the 2–8 keV energy range with the Imaging X-ray Polarimetry Explorer (IXPE) explore the magnetic field geometry and dynamics of the regions generating nonthermal radiation in relativistic jets of blazars. These jets, particularly in blazars whose spectral energy distribution peaks at X-ray energies, emit X-rays via synchrotron radiation from high-energy particles within the jet. IXPE observations of the X-ray-selected BL Lac–type blazar 1ES 1959+650 on 2022 May 3–4 showed a significant linear polarization degree of Π _x = 8.0% ± 2.3% at an electric-vector position angle ψ _x = 123° ± 8°. However, on 2022 June 9–12, only an upper limit of Π _x ≤ 5.1% could be derived (at the 99% confidence level). The degree of optical polarization at that time, Π _O ∼ 5%, is comparable to the X-ray measurement. We investigate possible scenarios for these findings, including temporal and geometrical depolarization effects. Unlike some other X-ray-selected BL Lac objects, there is no significant chromatic dependence of the measured polarization in 1ES 1959+650, and its low X-ray polarization may be attributed to turbulence in the jet flow with dynamical timescales shorter than 1 day.

Published
2024
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240. First Detection of Polarization in X-Rays for PSR B0540-69 and Its Nebula

Author

Fei Xie, Josephine Wong, Fabio La Monaca, Roger W. Romani, Jeremy Heyl, Philip Kaaret, Alessandro Di Marco, Niccolò Bucciantini, Kuan Liu, Chi-Yung Ng, Niccolò Di Lalla, Martin C. Weisskopf, Enrico Costa, Paolo Soffitta, Fabio Muleri, Matteo Bachetti, Maura Pilia, John Rankin, Sergio Fabiani, Iván Agudo, Lucio A. Antonelli, Luca Baldini, Wayne H. Baumgartner, Ronaldo Bellazzini, Stefano Bianchi, Stephen D. Bongiorno, Raffaella Bonino, Alessandro Brez, Fiamma Capitanio, Simone Castellano, Elisabetta Cavazzuti, Chien-Ting Chen, Stefano Ciprini, Alessandra De Rosa, Ettore Del Monte, Laura Di Gesu, Immacolata Donnarumma, Victor Doroshenko, Michal Dovčiak, Steven R. Ehlert, Teruaki Enoto, Yuri Evangelista, Riccardo Ferrazzoli, Javier A. Garcia, Shuichi Gunji, Kiyoshi Hayashida, Wataru Iwakiri, Svetlana G. Jorstad, Vladimir Karas, Fabian Kislat, Takao Kitaguchi, Jeffery J. Kolodziejczak, Henric Krawczynski, Luca Latronico, Ioannis Liodakis, Simone Maldera, Alberto Manfreda, Frédéric Marin, Andrea Marinucci, Alan P. Marscher, Herman L. Marshall, Francesco Massaro, Giorgio Matt, Ikuyuki Mitsuishi, Tsunefumi Mizuno, Michela Negro, Stephen L. O’Dell, Nicola Omodei, Chiara Oppedisano, Alessandro Papitto, George G. Pavlov, Abel L. Peirson, Matteo Perri, Melissa Pesce-Rollins, Pierre-Olivier Petrucci, Andrea Possenti, Juri Poutanen, Simonetta Puccetti, Brian D. Ramsey, Ajay Ratheesh, Oliver J. Roberts, Carmelo Sgrò, Patrick Slane, Gloria Spandre, Douglas A. Swartz, Toru Tamagawa, Fabrizio Tavecchio, Roberto Taverna, Yuzuru Tawara, Allyn F. Tennant, Nicholas E. Thomas, Francesco Tombesi, Alessio Trois, Sergey S. Tsygankov, Roberto Turolla, Jacco Vink, Kinwah Wu, Silvia Zane, IXPE Collaboration, Zorawar Wadiasingh, Wynn C. G. Ho, Alice K. Harding, Keith C. Gendreau, and Zaven Arzoumanian

Subjects
Pulsars, Pulsar wind nebulae, Polarimetry, Astrophysics, QB460-466
Abstract

We report on X-ray polarization measurements of the extragalactic Crab-like PSR B0540-69 and its Pulsar Wind Nebula (PWN) in the Large Magellanic Cloud, using a ∼850 ks Imaging X-ray Polarimetry Explorer (IXPE) exposure. The PWN is unresolved by IXPE. No statistically significant polarization is detected for the image-averaged data, giving a 99% confidence polarization upper limit (MDP _99 ) of 5.3% in the 2–8 keV energy range. However, a phase-resolved analysis detects polarization for both the nebula and pulsar in the 4–6 keV energy range. For the PWN defined as the off-pulse phases, the polarization degree (PD) of (24.5 ± 5.3)% and polarization angle (PA) of (78.1 ± 6.2)° is detected at 4.6 σ significance level, consistent with the PA observed in the optical band. In a single on-pulse window, a hint of polarization is measured at 3.8 σ with PD of (50.0 ± 13.1)% and PA of (6.2 ± 7.4)°. A “simultaneous” PSR/PWN analysis finds two bins at the edges of the pulse exceeding 3 σ PD significance, with PD of (68 ± 20)% and (62 ± 20)%; intervening bins at 2–3 σ significance have lower PD, hinting at additional polarization structure.

Published
2024
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242. The Large Area Detector onboard the eXTP mission

Author

Feroci, Marco, Ahangarianabhari, Mahdi, Ambrosi, Giovanni, Ambrosino, Filippo, Argan, Andrea, Barbera, Marco, Bayer, Joerg, Bellutti, Pierluigi, Bertucci, Bruna, Bertuccio, Giuseppe, Borghi, Giacomo, Bozzo, Enrico, Cadoux, Franck, Campana, Riccardo, Ceraudo, Francesco, Chen, Tianxiang, Cirrincione, Daniela, De Rosa, Alessandra, Del Monte, Ettore, Di Cosimo, Sergio, Diebold, Sebastian, Evangelista, Yuri, Fan, Qingmei, Favre, Yannick, Ficorella, Francesco, Fuschino, Fabio, Gevin, Olivier, Grassi, Marco, Hong, Bin, Mao, Hanqi, Karas, Vladimir, Kennedy, Tom, Labanti, Claudio, Limousin, Olivier, Cicero, Ugo Lo, Lu, Fang-Jun, Luo, Tao, Malcovati, Piero, Martindale, Adrian, Meuris, Aline, Michalska, Malgorzata, Morbidini, Alfredo, Muleri, Fabio, Orleanski, Piotr, Paltani, Stephane, Pan, Teng, Perinati, Emanuele, Picciotto, Antonino, Pohl, Martin, Rashevskaia, Irina, Santangelo, Andrea, Schanne, Stephane, Skup, Konrad, Svoboda, Jiri, Tenzer, Chris, Vacchi, Andrea, Walton, Dave, Winter, Berend, Wu, Xin, Xu, Yupeng, Zampa, Ganluigi, Zampa, Nicola, Zane, Silvia, Zdziarski, Andrzej, Zhang, Long, Zhang, Shu, Zhang, Shuang-Nan, Zhang, Wenda, Zhang, Xiaoli, Zhou, Yupeng, and Zorzi, Nicola

Subjects
Astrophysics - Instrumentation and Methods for Astrophysics
Abstract

The eXTP (enhanced X-ray Timing and Polarimetry) mission is a major project of the Chinese Academy of Sciences (CAS) and China National Space Administration (CNSA) currently performing an extended phase A study and proposed for a launch by 2025 in a low-earth orbit. The eXTP scientific payload envisages a suite of instruments (Spectroscopy Focusing Array, Polarimetry Focusing Array, Large Area Detector and Wide Field Monitor) offering unprecedented simultaneous wide-band X-ray spectral, timing and polarimetry sensitivity. A large European consortium is contributing to the eXTP study and it is expected to provide key hardware elements, including a Large Area Detector (LAD). The LAD instrument for eXTP is based on the design originally proposed for the LOFT mission within the ESA context. The eXTP/LAD envisages a deployed 3.4 m2 effective area in the 2-30 keV energy range, achieved through the technology of the large-area Silicon Drift Detectors - offering a spectral resolution of up to 200 eV FWHM at 6 keV - and of capillary plate collimators - limiting the field of view to about 1 degree. In this paper we provide an overview of the LAD instrument design, including new elements with respect to the earlier LOFT configuration., Comment: Paper presented at SPIE Space Telescopes and Instrumentation 2018

Published
2018
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243. The Wide Field Monitor onboard the eXTP mission

Author

Hernanz, M., Brandt, S., Feroci, M., Orleanski, P., Santangelo, A., Schanne, S., Wu, Xin, Zand, J. in't, Zhang, S. N., Xu, Y. P., Bozzo, E., Evangelista, Y., Gálvez, J. L., Tenzer, C., Zwart, F., Lu, F. J., Zhang, S., Chen, T. X., Ambrosino, F., Argan, A., Del Monte, E., Budtz-Jørgensen, C., Lund, N., Olsen, P., Mansanet, C., Campana, R., Fuschino, F., Labanti, C., Rachevski, A., Vacchi, A., Zampa, G., Zampa, N., Rashevskaya, I., Bellutti, P., Borghi, G., Ficorella, F., Picciotto, A., Zorzi, N., Limousin, O., and Meuris, A.

Subjects
Astrophysics - Instrumentation and Methods for Astrophysics, Astrophysics - High Energy Astrophysical Phenomena
Abstract

The eXTP (enhanced X-ray Timing and Polarimetry) mission is a major project of the Chinese Academy of Sciences (CAS) and China National Space Administration (CNSA) currently performing an extended phase A study and proposed for a launch by 2025 in a low-earth orbit. The eXTP scientific payload envisages a suite of instruments (Spectroscopy Focusing Array, Polarimetry Focusing Array, Large Area Detector and Wide Field Monitor) offering unprecedented simultaneous wide-band X-ray timing and polarimetry sensitivity. A large European consortium is contributing to the eXTP study and it is expected to provide key hardware elements, including a Wide Field Monitor (WFM). The WFM instrument for eXTP is based on the design originally proposed for the LOFT mission within the ESA context. The eXTP/WFM envisages a wide field X-ray monitor system in the 2-50 keV energy range, achieved through the technology of the large-area Silicon Drift Detectors. The WFM will consist of 3 pairs of coded mask cameras with a total combined Field of View (FoV) of 90x180 degrees at zero response and a source localization accuracy of ~1 arcmin. In this paper we provide an overview of the WFM instrument design, including new elements with respect to the earlier LOFT configuration, and anticipated performance., Comment: 16 pages, 15 figures, to appear in proceedings of SPIE, Space Telescopes and Instrumentation 2018: Ultraviolet to Gamma Ray

Published
2018

244. Correlation methods for the analysis of X-ray polarimetric signals

Author

Massaro, Enrico, Fabiani, Sergio, Campana, Riccardo, Costa, Enrico, Del Monte, Ettore, Muleri, Fabio, and Soffitta, Paolo

Subjects
Astrophysics - Instrumentation and Methods for Astrophysics
Abstract

X-ray polarimetric measurements are based on studying the distribution of the directions of scattered photons or photoelectrons and on the search of a sinusoidal modulation with a period of {\pi}. We developed two tools for investigating these angular distributions based on the correlations between counts in phase bins separated by fixed phase distances. In one case we use the correlation between data separated by half of the bin number (one period) which is expected to give a linear pattern. In the other case, the scatter plot obtained by shifting by 1/8 of the bin number (1/4 of period) transforms the sinusoid in a circular pattern whose radius is equal to the amplitude of the modulation. For unpolarized radiation these plots are reduced to a random point distribution centred at the mean count level. This new methods provide direct visual and simple statistical tools for evaluating the quality of polarization measurements and for estimating the polarization parameters. Furthermore they are useful for investigating distortions due to systematic effects.

Published
2018
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245. Effective refractive error coverage in adults aged 50 years and older: estimates from population-based surveys in 61 countries

Author

Bron, Alain, Cheng, Ching-Yu, Fernandes, Arthur, Friedman, David, Gazzard, Andrew, Kahloun, Rim, Kempen, John, Khairallah, Moncef, Lansingh, Van C, Leasher, Janet, Leveziel, Nicolas, Limburg, Hans, Nowak, Michal, Pesudovs, Konrad, Peto, Tunde, Rossetti, Luca, Tahhan, Nina, Varma, Rohit, Alemayehu, Wondu, Arditi, Aries, Dana, Reza, Del Monte, Monte, Deva, jenny, Dreer, Laura, Ehrlich, Josh, Ellwein, Leon, Hammond, Billy, Hartnett, Mary E, Ingram, April, Khanna, Rohit, Kim, Judy, Lim, Jennifer, Morse, Alan, Musch, David, Parodi, Maurizio B, Ramulu, Pradeep, Robin, Alan, Serle, Janet, Shen, Tueng, Sitorus, Rita S, Stambolian, Dwight, Topouzis, Fotis, Tsilimbaris, Miltiadis, Virgili, Gianni, West, Sheila, Ababora, Jafer K, AlSawahli, Heba, Andriamanjato, Hery Harimanitra, Barrenechea, Rosario, Batlle, Juan F, Burnett, Anthea M, Finger, Robert P, Gallarreta, Marcelo, Gomez-Bastar, Pedro A, Gurung, Reeta, Jain, Elesh, Kabona, George E, Kalua, Khumbo, Kandeke, Levi, Karimurio, Jefitha, Kikira, Susan A, Kulkarni, Sucheta, Mathenge, Wanjiku, Mishra, Sailesh Kumar, Mohammadi, Seyed Farzad, Mörchen, Manfred, Muhammad, Nasiru, Mutati, Grace C, Nano, Maria Eugenia, Németh, János, Paduca, Ala, Páez, Alexander, Rabiu, M Mansur, Rif'ati, Lutfah, Salowi, Mohamad Aziz, Sapkota, Yuddha D, Sargent, Nicholas, Thoufeeq, Ubeydulla, Villalobos, Astrid V, Xiao, Biaxiang, Yee Melgar, Mariano, Zhang, Xiu Juan, Bourne, Rupert Richard Alexander, Cicinelli, Maria Vittoria, Sedighi, Tabassom, Tapply, Ian H, McCormick, Ian, Jonas, Jost B, Congdon, Nathan G, Ramke, Jacqueline, Naidoo, Kovin S, Fricke, Timothy R, Burton, Matthew J, Müller, Andreas, Bikbov, Mukharram M, Furtado, João M, Kyari, Fatima, He, Mingguang, Wang, Ya Xing, Vijaya, Lingam, Nangia, Vinay, Brian, Garry, Emamian, Mohammad Hassan, Fotouhi, Akbar, Hashemi, Hassan, Khandekar, Rajiv B, Marmamula, Srinivas, Salomão, Solange, George, Ronnie, Kazakbaeva, Gyulli, Braithwaite, Tasanee, Casson, Robert J, Iwase, Aiko, Gupta, Noopur, Abdianwall, Mohammad H, Wong, Tien Y, Wang, Ningli, Taylor, Hugh R, Flaxman, Seth R, Keel, Stuart, and Resnikoff, Serge

Published
2022
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247. Exploring Multispecies Assemblages in Roman Urban Gardening Initiatives

Author

Beatrice Del Monte

Subjects
urban gardening, post-anthropocentrism, ailanthus altissima, mellifera bee, multispecies ethnography, Science, Science (General), Q1-390
Abstract

In this article I will discuss the potential of using the assemblage thinking in multispecies ethnography, as a method for developing postanthropocentric situated accounts. It is an extremely relevant tool with which to relate to make emerge how space is co-constructed through hybrid associations of human and nonhuman actors, which exceed human intentionality. Reading entanglements through a material-semiotic approach provides interesting analyses of the exploitation of the nonhuman on a global scale, but also offers stories of possible situated multispecies relationships of care. These relations are not universal essences, but situated entanglements in which nonhuman actors play an active role. Relying on STS feminist reflections, focusing on care could have the potential of unveiling less anthropocentric more-than-human relations, showing how being depend on each other.

Published
2022
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248. Parents’ satisfaction of tele-rehabilitation for children with neurodevelopmental disabilities during the COVID-19 pandemic

Author

Pamela Frigerio, Liliana Del Monte, Aurora Sotgiu, Costantino De Giacomo, and Aglaia Vignoli

Subjects
Parents’ satisfaction, Tele-rehabilitation, COVID-19, Neurodevelopmental disabilities, Medicine (General), R5-920
Abstract

Abstract Background The use of tele-rehabilitation in children was limited before the COVID-19 pandemic, due to culture, technology access, regulatory and reimbursement barriers. Methods The study was conducted according to the CHERRIES (Checklist for reporting results of internet E-surveys) guidelines in order to provide quantitative and qualitative data about experience of patients with disabilities and their caregivers during Phase 1 of the COVID-19 pandemic, and their level of satisfaction. An online survey was developed using Google Forms and sent via email. The outcome measures were rated using a 5-point Likert Scale. Two additional open-ended questions were used to collect qualitative data. Results One hundred twenty-eight out of 261 families responded to the survey: 80.5% of the caregivers reported they were satisfied with the tele-rehabilitation. More than a half (53%) of the families reported a high level of satisfaction with the involvement they received in defining and sharing of rehabilitation goals. Conclusions The implementation of telehealth during the COVID-19 lockdown has allowed us to gain more information about the potential of tele-rehabilitation, and resulted in an excellent satisfaction of caregivers. With appropriate education and consistent models of care, an increased use of telehealth may provide advances in remote patient care. Trial registration Not applicable.

Published
2022
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249. The thin line that made the difference: a case report on a Bosniak IIF renal cystic mass treated with cyst decortication

Author

Ali Forookhi, Marco Bicchetti, Sara Lucciola, Angelo Porreca, Gian Maria Busetto, and Maurizio Del Monte

Subjects
Renal cyst, Bosniak classification, Computed tomography, Magnetic resonance imaging, Medical physics. Medical radiology. Nuclear medicine, R895-920
Abstract

Abstract Background Among all benign kidney lesions, renal cysts are the most common type. In the proposed update of 2019, the Bosniak classification of cystic renal masses is used to classify renal masses according to their likelihood of malignancy, both on computed tomography (CT) and on magnetic resonance imaging (MRI). Case presentation A middle-aged Caucasian male presented to our department with chronic right flank pain. Imaging studies revealed a right renal Bosniak IIF cyst, later complicated by traumatic haemorrhage. The patient consequently underwent cyst decortication for symptom relief. Biopsy results from samples taken during the laparoscopic operation revealed ISUP grade 1 cystic clear cell carcinoma. Conclusion The treatment of Bosniak IIF cysts has long been a matter of debate. As a result of scarcity of data on the probability of malignancy in MRI using the new classification, such cysts should be carefully scrutinised and staged before choosing a treatment option. Retroperitoneal seeding should always be considered in interventions involving an incomplete resection margin or cyst drainage.

Published
2022
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250. Radiation-induced effects on the RIGEL ASIC

Author

Ceraudo, F., Dedolli, I., Cirrincione, D., Del Monte, E., Mele, F., Ambrosino, F., Bellutti, P., Bertuccio, G., Borghi, G., Campana, R., Caselle, M., Evangelista, Y., Feroci, M., Ficorella, F., Fiorini, M., Fuschino, F., Gandola, M., Grassi, M., Labanti, C., Loffredo, P., Malcovati, P., Picciotto, A., Rachevski, A., Rashevskaya, I., Tobia, A., Vacchi, A., Volpe, A., Zampa, G., Zampa, N., and Zorzi, N.

Published
2022
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