37,571 results on '"Furlan A"'
Search Results
202. Lumbar Spine Densitometry in People with Spinal Cord Injury: Investigation of Potential Sources of Errors
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Ponzano, Matteo, Giangregorio, Lora M., Furlan, Julio C., Gulasingam, Sivakumar, Callaghan, Jack P., and Craven, B. Catharine
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- 2024
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203. Experimental design of size variation in albumin nanoparticles synthesized by electron beam
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Ferreira, Aryel H., Lima, Caroline S.A., Cunha da Cruz, Cassia Priscila, Freitas, Lucas F., Furlan, Gustavo N., de Lima, Robson C., Sarriés, Gabriel Adrián, and Lugão, Ademar B.
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- 2024
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204. The curious case of the rare Citrobacter pasteurii isolated from an endangered primate in Brazil
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Furlan, João Pedro Rueda, Sellera, Fábio Parra, Gonzalez, Irys Hany Lima, Ramos, Patrícia Locosque, and Stehling, Eliana Guedes
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- 2024
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205. Gene expression dynamics during temperature-dependent sex determination in a sea turtle
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Martínez-Pacheco, Mónica, Díaz-Barba, Karina, Pérez-Molina, Rosario, Marmolejo-Valencia, Alejandro, Collazo-Saldaña, Pedro, Escobar-Rodríguez, Mariana, Sánchez-Pérez, Mishael, Meneses-Acosta, Angélica, Martínez-Rizo, Abril B., Sánchez-Pacheco, Abdallah U., Furlan-Magaril, Mayra, Merchant-Larios, Horacio, and Cortez, Diego
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- 2024
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206. Quantifying heuristic evaluation
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Gonzalez Capdevila, Marc, Pistili Rodrigues, Karine Aparecida, Sartório Furlan, Tales Augusto, and Granollers, Toni
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- 2025
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207. Efficacy of Dexmedetomidine as an Adjuvant to Local Anesthetics in Peribulbar Block: A Meta-analysis With Trial-Sequential Analysis
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Pereira, Eduardo Maia Martins, Viana, Patrícia, da Silva, Rodrigo Araujo Monteiro, Silott, Pedro Furlan, and Amaral, Sara
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- 2025
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208. Soil-aggregate-cement mixtures for base pavement layers: A strength and stiffness characterization
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Tavares, André Lapa de Moraes, Furlan, Ana Paula, Fabbri, Glauco Tulio Pessa, and Pedreira Junior, Jorge Ubirajara
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- 2025
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209. Bioadhesive film for the delivery of local anesthetics to the buccal mucosa: ex-vivo and in-vivo evaluation
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Tofoli, Giovana Radomille, Boava Papini, Juliana Zampoli, Furlan, Beatriz, Saia Cereda, Cíntia Maria, Calafatti, Silvana Aparecida, de Paula, Eneida, Franz-Montan, Michelle, Santi, Patrizia, Nicoli, Sara, Pescina, Silvia, Ribeiro de Araujo, Daniele, Pelosine, Agatha Maria, and Padula, Cristina
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- 2025
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210. Chrysin analysis by QuEChERS modified method and HPLC-DAD, antioxidant potential and in vitro gastrointestinal digestion of Passiflora caerulea
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Filho, Carlos Borges, Kemmerich, Magali, Furlan, Júnior Mendes, Santos, Betânia Nascimento dos, de Deus, Cassandra, Pinto, Vandré Sonza, Rangel, Caroline Pinto, Riste, Uashington da Silva, Feijó, Adriane Lettnin Roll, Dahleh, Mustafa Munir Mustafa, Prigol, Marina, and de Menezes, Cristiano Ragagnin
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- 2025
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211. Condensation flow inside tubes: A review of heat transfer coefficient measurement techniques, experimental databases and prediction methods
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Marchetto, Daniel Borba, Marinheiro, Maurício Mani, Souza Netto, Arlindo Theodoro de, Furlan, Gabriel, Ribatski, Gherhardt, Thome, John Richard, and Tibiriçá, Cristiano Bigonha
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- 2025
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212. Optimising Warehouse Order Picking: Real Case Application in the Shoe Manufacturing Industry
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Rodrigo Furlan de Assis, William de Paula Ferreira, Alexandre Frias Faria, Luis Antonio Santa-Eulalia, Mustapha Ouhimmou, and Ali Gharbi
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Random storage location ,mixed shelving ,picker routing ,genetic algorithm ,Electrical engineering. Electronics. Nuclear engineering ,TK1-9971 - Abstract
Order picking is a critical and labour-intensive warehouse management operation that involves removing items from storage locations to fulfil customer orders. This paper analyses a new order-picking problem based on the real case of a Canadian shoe manufacturer characterised by a warehouse with random storage, where different product types can be assigned to a single storage location. While maximising space utilisation, considering the high number of Stock Keeping Units, this storage approach makes the creation of efficient picking routes challenging, increasing the effort needed to complete picking orders. To address this challenge, we present the Genetic Route Optimisation algorithm for optimising order-picking routes. Our methodology involved testing the proposed algorithm using real-world data derived from the company’s Warehouse Management System. The results demonstrate a reduction in picking distances, highlighting the effectiveness of the Genetic Route Optimisation algorithm in optimising picking routes in a random storage environment. As well as presenting a practical application case, the study highlights the potential of the proposed algorithm to improve operational efficiency in warehouse environments. It also paves the way for future research in warehouse logistics, especially by adapting similar algorithmic strategies to various complex and dynamic warehouse environments, thus advancing the field of warehouse management.
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- 2024
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213. The role of functional thiolated molecules on the enhanced electronic transport of interconnected MoS$_2$ nanostructures
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Freire, Rafael L. H., de Lima, Felipe Crasto, de Oliveira, Rafael Furlan, Capaz, Rodrigo B., and Fazzio, Adalberto
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Condensed Matter - Materials Science - Abstract
Molecular linkers have emerged as an effective strategy to improve electronic transport properties on solution-processed layered materials via defect functionalization. However, a detailed discussion on the microscopic mechanisms behind the beneficial effects of functionalization is still missing. Here, by first-principles calculations based on density functional theory, we investigate the effects on the electronic properties of interconnected MoS$_2$ model flakes systems upon functionalization with different thiol molecule linkers, namely thiophenol, 1,4-benzenedithiol, 1,2-ethanedithiol, and 1,3-propanedithiol. The bonding of benzene- and ethanedithiol bridging adjacent armchair MoS$_2$ nanoflakes leads to electronic states just above or at the Fermi level, thus forming a molecular channel for electronic transport between flakes. In addition, the molecular linker reduces the potential barrier for thermally activated hopping between neighboring flakes, improving the conductivity as verified in experiments. The comprehension of such mechanisms helps in future developments of solution-processed layered materials for use on 2D electronic devices.
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- 2022
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214. TOI-1759 b: a transiting sub-Neptune around a low mass star characterized with SPIRou and TESS
- Author
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Martioli, Eder, Hébrard, Guillaume, Fouqué, Pascal, Artigau, Étienne, Donati, Jean-François, Cadieux, Charles, Bellotti, Stefano, Etangs, Alain Lecavelier des, Doyon, Réne, Nascimento Jr., J. -D. do, Arnold, L., Carmona, A., Cook, N. J., Cortes-Zuleta, P., de Almeida, L., Delfosse, X., Folsom, C. P., König, P. -C., Moutou, C., Ould-Elhkim, M., Petit, P., Stassun, K. G., Vidotto, A. A., Vandal, T., Benneke, B., Boisse, I., Bonfils, X., Boyd, P., Brasseur, C., Charbonneau, D., Cloutier, R., Collins, K., Cristofari, P., Crossfield, I., Díaz, R. F., Fausnaugh, M., Figueira, P., Forveille, T., Furlan, E., Girardin, E., Gnilka, C. L., da Silva, J. Gomes, Gu, P. -G., Guerra, P., Howell, S. B., Hussain, G. A. J., Jenkins, J. M., Kiefer, F., Latham, D. W., Matson, R. A., Matthews, E. C., Morin, J., Naves, R., Ricker, G., Seager, S., Takami, M., Twicken, J. D., Vanderburg, A., Vanderspek, R., and Winn, J.
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Astrophysics - Earth and Planetary Astrophysics ,Astrophysics - Solar and Stellar Astrophysics - Abstract
We report the detection and characterization of the transiting sub-Neptune TOI-1759 b, using photometric time-series from TESS and near infrared spectropolarimetric data from SPIRou on the CFHT. TOI-1759 b orbits a moderately active M0V star with an orbital period of $18.849975\pm0.000006$ d, and we measure a planetary radius and mass of $3.06\pm0.22$ R$_\oplus$ and $6.8\pm2.0$ M$_\oplus$. Radial velocities were extracted from the SPIRou spectra using both the CCF and the LBL methods, optimizing the velocity measurements in the near infrared domain. We analyzed the broadband SED of the star and the high-resolution SPIRou spectra to constrain the stellar parameters and thus improve the accuracy of the derived planet parameters. A LSD analysis of the SPIRou Stokes $V$ polarized spectra detects Zeeman signatures in TOI-1759. We model the rotational modulation of the magnetic stellar activity using a GP regression with a quasi-periodic covariance function, and find a rotation period of $35.65^{+0.17}_{-0.15}$ d. We reconstruct the large-scale surface magnetic field of the star using ZDI, which gives a predominantly poloidal field with a mean strength of $18\pm4$ G. Finally, we perform a joint Bayesian MCMC analysis of the TESS photometry and SPIRou RVs to optimally constrain the system parameters. At $0.1176\pm0.0013$ au from the star, the planet receives $6.4$ times the bolometric flux incident on Earth, and its equilibrium temperature is estimated at $433\pm14$ K. TOI-1759 b is a likely gas-dominated sub-Neptune with an expected high rate of photoevaporation. Therefore, it is an interesting target to search for neutral hydrogen escape, which may provide important constraints on the planetary formation mechanisms responsible for the observed sub-Neptune radius desert., Comment: Accepted for publication in the 10. Planets and planetary systems section of Astronomy & Astrophysics
- Published
- 2022
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215. Validation of 13 Hot and Potentially Terrestrial TESS Planets
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Giacalone, Steven, Dressing, Courtney D., Hedges, Christina, Kostov, Veselin B., Collins, Karen A., Jensen, Eric L. N., Yahalomi, Daniel A., Bieryla, Allyson, Ciardi, David R., Howell, Steve B., Lillo-Box, Jorge, Barkaoui, Khalid, Winters, Jennifer G., Matthews, Elisabeth, Livingston, John H., Quinn, Samuel N., Safonov, Boris S., Cadieux, Charles, Furlan, E., Crossfield, Ian J. M., Mandell, Avi M., Gilbert, Emily A., Kruse, Ethan, Quintana, Elisa V., Ricker, George R., Seager, S., Winn, Joshua N., Jenkins, Jon M., Adkins, Britt Duffy, Baker, David, Barclay, Thomas, Barrado, David, Batalha, Natalie M., Belinski, Alexander A., Benkhaldoun, Zouhair, Buchhave, Lars A., Cacciapuoti, Luca, Charbonneau, David, Chontos, Ashley, Christiansen, Jessie L., Cloutier, Ryan, Collins, Kevin I., Conti, Dennis M., Cutting, Neil, Dixon, Scott, Doyon, René, Mufti, Mohammed El, Esparza-Borges, Emma, Essack, Zahra, Fukui, Akihiko, Gan, Tianjun, Gary, Kaz, Ghachoui, Mourad, Gillon, Michaël, Girardin, Eric, Glidden, Ana, Gonzales, Erica J., Guerra, Pere, Horch, Elliott P., Helminiak, Krzysztof G., Howard, Andrew W., Huber, Daniel, Irwin, Jonathan M., Isopi, Giovanni, Jehin, Emmanuël, Kagetani, Taiki, Kane, Stephen R., Kawauchi, Kiyoe, Kielkopf, John F., Lewin, Pablo, Luker, Lindy, Lund, Michael B., Mallia, Franco, Mao, Shude, Massey, Bob, Matson, Rachel A., Mireles, Ismael, Mori, Mayuko, Murgas, Felipe, Narita, Norio, O`Dwyer, Tanner, Petigura, Erik A., Polanski, Alex S., Pozuelos, Francisco J., Palle, Enric, Parviainen, Hannu, Plavchan, Peter P., Relles, Howard M., Robertson, Paul, Rose, Mark E., Rowden, Pamela, Roy, Arpita, Savel, Arjun B., Schlieder, Joshua E., Schnaible, Chloe, Schwarz, Richard P., Sefako, Ramotholo, Selezneva, Aleksandra, Skinner, Brett, Stockdale, Chris, Strakhov, Ivan A., Tan, Thiam-Guan, Torres, Guillermo, Tronsgaard, René, Twicken, Joseph D., Vermilion, David, Waite, Ian A., Walter, Bradley, Wang, Gavin, Ziegler, Carl, and Zou, Yujie
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Astrophysics - Earth and Planetary Astrophysics - Abstract
The James Webb Space Telescope (JWST) will be able to probe the atmospheres and surface properties of hot, terrestrial planets via emission spectroscopy. We identify 18 potentially terrestrial planet candidates detected by the Transiting Exoplanet Survey Satellite (TESS) that would make ideal targets for these observations. These planet candidates cover a broad range of planet radii ($R_{\rm p} \sim 0.6 - 2.0 R_\oplus$) and orbit stars of various magnitudes ($K_s = 5.78 - 10.78$, $V = 8.4 - 15.69$) and effective temperatures ($T_{\rm eff }\sim 3000 - 6000$ K). We use ground-based observations collected through the TESS Follow-up Observing Program (TFOP) and two vetting tools -- DAVE and TRICERATOPS -- to assess the reliabilities of these candidates as planets. We validate 13 planets: TOI-206 b, TOI-500 b, TOI-544 b, TOI-833 b, TOI-1075 b, TOI-1411 b, TOI-1442 b, TOI-1693 b, TOI-1860 b, TOI-2260 b, TOI-2411 b, TOI-2427 b, and TOI-2445 b. Seven of these planets (TOI-206 b, TOI-500 b, TOI-1075 b, TOI-1442 b, TOI-2260 b, TOI-2411 b, and TOI-2445 b) are ultra-short-period planets. TOI-1860 is the youngest ($133 \pm 26$ Myr) solar twin with a known planet to date. TOI-2260 is a young ($321 \pm 96$ Myr) G dwarf that is among the most metal-rich ([Fe/H] = $0.22 \pm 0.06$ dex) stars to host an ultra-short-period planet. With an estimated equilibrium temperature of $\sim 2600$ K, TOI-2260 b is also the fourth hottest known planet with $R_{\rm p} < 2 \, R_\oplus$.
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- 2022
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216. Evaluating the root causes of fatigue and associated risk factors in the Brazilian regular aviation industry
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Rodrigues, Tulio E., Fischer, Frida M., Helene, Otaviano, Antunes, Eduardo, Furlan, Eduardo, Morteo, Eduardo, Menquini, Alfredo, Lisboa, João, Frank, Arnaldo, Simões, Alexandre, Papazian, Karla, and Helene, André F.
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Statistics - Applications ,Physics - Physics and Society - Abstract
This work evaluates the potential root causes of fatigue using a biomathematical model and a robust sample of aircrew rosters from the Brazilian regular aviation. The fatigue outcomes derive from the software Sleep, Activity, Fatigue, and Task Effectiveness Fatigue Avoidance Scheduling Tool (SAFTE-FAST). The average minimum SAFTE-FAST effectiveness during critical phases of flight decreases cubically with the number of shifts that elapse totally or partially between mid-night and 6 a.m. within a 30-day period ($N_{NS}$). As a consequence, the relative fatigue risk increases by 23.3% (95% CI, 20.4-26.2%) when increasing $N_{NS}$ from 1 to 13. The average maximum equivalent wakefulness in critical phases also increases cubically with the number of night shifts and exceeds 24 hours for rosters with $N_{NS}$ above 10. The average fatigue hazard area in critical phases of flight varies quadratically with the number of departures and landings within 2 and 6 a.m. ($N_{Wocl}$). These findings demonstrate that both $N_{NS}$ and $ N_{Wocl}$ should be considered as key performance indicators and be kept as low as reasonably practical when building aircrew rosters. The effectiveness scores at 30 minute time intervals allowed a model estimate for the relative fatigue risk as a function of the time of the day, whose averaged values show reasonable qualitative agreement with previous measurements of pilot errors. Tailored analyses of the SAFTE-FAST inputs for afternoon naps before night shifts, commuting from home to station and vice-versa, and bedtime before early-start shifts show relevant group effects ($p < 0.001$) comparing the groups with and without afternoon naps, with one or two hours of commuting and with or without the advanced bedtime feature of the SAFTE-FAST software, evidencing the need of a better and more accurate understanding of these parameters when modelling fatigue risk factors., Comment: 17 pages and 6 figures
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- 2022
217. The Rate, Amplitude and Duration of Outbursts from Class 0 Protostars in Orion
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Zakri, W., Megeath, S. T., Fischer, W. J., Gutermuth, Robert, Furlan, Elise, Hartmann, Lee, Karnath, Nicole, Osorio, Mayra, Safron, Emily, Stanke, Thomas, Stutz, Amelia M., Tobin, John J., Allen, Thomas S., Federman, Sam, Habel, Nolan, Manoj, P., Narang, Mayank, Pokhrel, Riwaj, Rebull, Luisa, Sheehan, Patrick D., and Watson, Dan M.
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Astrophysics - Solar and Stellar Astrophysics ,Astrophysics - Astrophysics of Galaxies - Abstract
At least half of a protostar's mass is accreted in the Class 0 phase, when the central protostar is deeply embedded in a dense, infalling envelope. We present the first systematic search for outbursts from Class 0 protostars in the Orion clouds. Using photometry from Spitzer/IRAC spanning 2004 to 2017, we detect three outbursts from Class 0 protostars with $\ge 2$ mag changes at 3.6 or 4.5 $\mu$m. This is comparable to the magnitude change of a known protostellar FU Ori outburst. Two are newly detected bursts from the protostars HOPS 12 and 124. The number of detections implies that Class 0 protostars burst every 438 yr, with a 95% confidence interval of 161 to 1884 yr. Combining Spitzer and WISE/NEOWISE data spanning 2004-2019, we show that the bursts persist for more than nine years with significant variability during each burst. Finally, we use $19-100$ $\mu$m photometry from SOFIA, Spitzer and Herschel to measure the amplitudes of the bursts. Based on the burst interval, a duration of 15 yr, and the range of observed amplitudes, 3-100% of the mass accretion during the Class 0 phase occurs during bursts. In total, we show that bursts from Class 0 protostars are as frequent, or even more frequent, than those from more evolved protostars. This is consistent with bursts being driven by instabilities in disks triggered by rapid mass infall. Furthermore, we find that bursts may be a significant, if not dominant, mode of mass accretion during the Class 0 phase., Comment: Accepted to ApJL
- Published
- 2022
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218. Transcutaneous vagus nerve stimulation as a potential novel treatment for cyclic vomiting syndrome: a first case report
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Carandina, Angelica, Scatà, Costanza, Furlan, Ludovico, Bellocchi, Chiara, Tobaldini, Eleonora, and Montano, Nicola
- Published
- 2023
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219. Non-planar slicing for filled free-form geometries in robot-based FDM
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Insero, Federico, Furlan, Valentina, and Giberti, Hermes
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- 2023
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220. A biallelic variant in COX18 cause isolated Complex IV deficiency associated with neonatal encephalo-cardio-myopathy and axonal sensory neuropathy
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Ronchi, Dario, Garbellini, Manuela, Magri, Francesca, Menni, Francesca, Meneri, Megi, Bedeschi, Maria Francesca, Dilena, Robertino, Cecchetti, Valeria, Picciolli, Irene, Furlan, Francesca, Polimeni, Valentina, Salani, Sabrina, Pezzoli, Laura, Fortunato, Francesco, Bellini, Matteo, Piga, Daniela, Ripolone, Michela, Zanotti, Simona, Napoli, Laura, Ciscato, Patrizia, Sciacco, Monica, Mangili, Giovanna, Mosca, Fabio, Corti, Stefania, Iascone, Maria, and Comi, Giacomo Pietro
- Published
- 2023
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221. Development of a “Geo-Tagged” tumor sample registry: intra-operative linkage of sample location to imaging
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Lynes, John, Khan, Irfan, Aguilera, Carlos, Rubino, Sebastian, Thompson, Zachary, Etame, Arnold B., Liu, James K. C., Beer-Furlan, Andre, Tran, Nam D., Macaulay, Robert J. B., and Vogelbaum, Michael A.
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- 2023
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222. Workplace and non-workplace cannabis use and the risk of workplace injury: Findings from a longitudinal study of Canadian workers
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Carnide, Nancy, Landsman, Victoria, Lee, Hyunmi, Frone, Michael R., Furlan, Andrea D., and Smith, Peter M.
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- 2023
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223. Multidrug-resistant Shiga toxin-producing Escherichia coli and hybrid pathogenic strains of bovine origin
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Furlan, João Pedro Rueda, Ramos, Micaela Santana, dos Santos, Lucas David Rodrigues, da Silva Rosa, Rafael, and Stehling, Eliana Guedes
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- 2023
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224. Work satisfaction and job permanence in artistic careers: the case of musicians in Belo Horizonte, Brazil
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da Silva Henrique, Jonas, Machado, Ana Flávia, and Antigo, Mariangela Furlan
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- 2023
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225. Genomic features of an extensively drug-resistant and NDM-1–positive Klebsiella pneumoniae ST340 isolated from river water
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Furlan, João Pedro Rueda, da Silva Rosa, Rafael, Ramos, Micaela Santana, dos Santos, Lucas David Rodrigues, Savazzi, Eduardo Angelino, and Stehling, Eliana Guedes
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- 2023
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226. Enhancing productivity and efficiency in conventional laser metal deposition process for Inconel 718 – Part II: advancing the process performance
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Maffia, Simone, Chiappini, Federico, Maggiani, Gianluca, Furlan, Valentina, Guerrini, Massimo, and Previtali, Barbara
- Published
- 2023
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227. Enhancing productivity and efficiency in conventional laser metal deposition process for Inconel 718 - part I: the effects of the process parameters
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Maffia, Simone, Chiappini, Federico, Maggiani, Gianluca, Furlan, Valentina, Guerrini, Massimo, and Previtali, Barbara
- Published
- 2023
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228. The significance of geological structures on the subsidence phenomenon at the Maceió salt dissolution field (Brazil)
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Hartwig, Marcos Eduardo, Gama, Fábio Furlan, da Silva, Jefferson Lins, Jofré, Gonzalo Corral, and Mura, José Claudio
- Published
- 2023
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229. Esmethadone-HCl (REL-1017): a promising rapid antidepressant
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Fava, Maurizio, Stahl, Stephen M., De Martin, Sara, Mattarei, Andrea, Bettini, Ezio, Comai, Stefano, Alimonti, Andrea, Bifari, Francesco, Pani, Luca, Folli, Franco, Guidetti, Clotilde, Furlan, Alberto, Sgrignani, Jacopo, Locatelli, Patrizia, Cavalli, Andrea, O’Gorman, Cedric, Traversa, Sergio, Inturrisi, Charles E., Pappagallo, Marco, and Manfredi, Paolo L.
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- 2023
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230. Does Ovariectomy Affect the Mechanics of the Mandibular Alveolar Bone Structure of Wistar Rats Subjected to Tooth Loss and Modified Diet?—A FEA Study
- Author
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Camila C. Furlan, Alexandre R. Freire, Beatriz C. Ferreira-Pileggi, Luciane N. O. Watanabe, Paulo R. Botacin, Felippe B. Prado, and Ana Cláudia Rossi
- Subjects
osteoporosis ,mandible ,finite element method ,diet ,tooth ,Biology (General) ,QH301-705.5 - Abstract
The aim of this study was to evaluate the mechanical effect of ovariectomy, diet, and tooth extraction on the bone structure of the mandible of Wistar rats. Mandibles from 40 female Wistar rats were used, divided into rats with ovariectomy surgery or surgical simulation. Half of the rats had the right upper incisor extracted and a soft diet was introduced for half of the animals for 30 days. After euthanasia, microtomography of the mandibles was performed for bone segmentation to construct three-dimensional models. Each mandible was subjected to a three-point bending test. The simulation by finite element method was configured according to the protocol for positioning the part on the support and force action by the load cell defined in the mechanical tests. Stress dissipation was described qualitatively on a color scale distributed in ranges of stress values. All models showed a higher concentration of stresses in the regions of force action and in the support regions, with differences in stress values and locations. Diet and dental condition interfered in the distribution of stresses, with the lateral surface of the mandible being more influenced by diet and the medial surface of the mandible by diet and dental condition.
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- 2024
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231. Invasive Pneumococcal Diseases in People over 65 in Veneto Region Surveillance
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Silvia Cocchio, Claudia Cozzolino, Andrea Cozza, Patrizia Furlan, Irene Amoruso, Francesca Zanella, Filippo Da Re, Debora Ballarin, Gloria Pagin, Davide Gentili, Michele Tonon, Francesca Russo, Tatjana Baldovin, and Vincenzo Baldo
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invasive bacterial diseases ,Streptococcus pneumoniae ,elderly ,surveillance ,pneumococcal vaccination ,Medicine - Abstract
Background: Elderly individuals over 65, along with children under 5, are the most affected by invasive pneumococcal diseases (IPDs). Monitoring vaccination coverage and conducting surveillance are essential for guiding evidence-based prevention campaigns and public health measures. Methods: Since 2007, the Veneto Region has relied on three sources for surveillance of invasive bacterial infections, contributing to an increase in reported IPD cases. This study analyzed notifications related to individuals aged ≥65 years from 2007 to 2023. Results: A total of 1527 cases of IPDs in elderly individuals were reported between 2007 and 2023. The notification rate significantly increased from 5.61 to 14.63 per 100,000 inhabitants, despite underreporting during the COVID-19 pandemic. Cases associated with sepsis increased from 3.89 to 9.58 per 100,000, while notifications of meningitis and case fatality rates remained stable at 1.5 per 100,000 and 11.8%, respectively. Serotyping was not performed in 52% of the notifications. The most common serotypes were 3 (21.6%), 8 (11.1%), and 19A (5.0%), with fluctuations over time. There was a significant decline in serotypes covered by PCV7 and PCV13 and an increase in non-vaccine serotypes. Conclusions: The regional surveillance system allows for an increasingly comprehensive profile of the epidemiological landscape of IPDs in Veneto. However, the surveillance of pneumococcal infections still presents challenges. The currently available data are likely to be underestimated, mainly referring to the most severe cases, and the serotyping necessary to identify the etiological agent is still not often performed.
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- 2024
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232. Scaling up the Two-Stage Countercurrent Extraction of Oil and Protein from Green Coffee Beans: Impact of Proteolysis on Extractability, Protein Functionality, and Oil Recovery
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Almeida, Flávia Souza, Dias, Fernanda Furlan Gonçalves, Sato, Ana Carla Kawazoe, and De Moura Bell, Juliana Maria Leite Nobrega
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Agricultural ,Veterinary and Food Sciences ,Food Sciences ,Green coffee protein ,Coffee oil ,Countercurrent extraction ,Scale-up ,Functional properties ,Oil recovery ,Agricultural Biotechnology ,Biotechnology ,Food sciences ,Chemical engineering - Abstract
Green coffee processing has been hindered by low oil extraction yields from mechanical pressing and the need of using flammable and hazardous solvents for defatting the protein-rich cake before subsequent protein extraction. To replace the use of flammable solvents and enable the simultaneous extraction of lipids and proteins from green coffee beans at reduced water usage, a multistage countercurrent extraction process was scaled up from 0.05 to 1.14 kg and evaluated regarding protein and oil extractability, physicochemical and functional properties of the extracted protein, and oil recovery. Enzymatic extraction increased protein extractability by ~13% while achieving similar oil extractability when not using enzymes (55%). Proteolysis resulted in the release of smaller proteins with reduced surface hydrophobicity and higher solubility at acidic pH (3.0–5.0). The physicochemical changes observed due to proteolysis resulted in the formation of emulsions with reduced resistance against enzymatic and chemical demulsification strategies, enhancing the recovery of the extracted oil (48.6–51.0%). Proteolysis did not alter the high in vitro digestibility of green coffee proteins (up to 99%) or their emulsifying properties at most pH values evaluated. However, proteolysis did reduce the foaming properties of the hydrolysates compared with larger molecular weight proteins. These findings revealed the impact of extraction conditions on the extractability and structural modifications altering the functionality of green coffee proteins and the synergistic impact of extraction and demulsification strategies on the recovery of the extracted oil, paving the way for the development of structure–function processes to effectively produce green coffee proteins with desired functionality.
- Published
- 2022
233. Epigenetic modulation with oral histone deacetylase (HDAC) inhibitor as a new treatment option in JIA
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Damjanov N, Furlan A, Vojinovic J, D’Urzo C, and Dinarello CA
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Pediatrics ,RJ1-570 ,Diseases of the musculoskeletal system ,RC925-935 - Published
- 2011
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234. Contact processes on fragmented domains
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Ibagon, I., Furlan, A. P., and Dickman, Ronald
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Condensed Matter - Statistical Mechanics ,Quantitative Biology - Populations and Evolution - Abstract
Motivated by recent findings of enhanced species survival when fragmented habitats are reconnected through narrow strips of land [S. Pimm, and C. N. Jenkins, Am. Sci. {\bf 107}(3), 162 (2019).], we study the effect of a corridor connecting two square regions on the survival time of three models exhibiting extinction/survival phase transitions: the basic contact process (CP), the diffusive contact process, and the two-species symbiotic contact process (2SCP). We find that connecting the regions generally increases the survival time for $\lambda\ge \lambda_c$, where $\lambda$ is the reproduction rate and $\lambda_c$ its critical value. The enhancement of the survival time increases with $\lambda$, and is largest in the 2SCP.
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- 2021
235. A 38 Million Year Old Neptune-Sized Planet in the Kepler Field
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Bouma, L. G., Curtis, J. L., Masuda, K., Hillenbrand, L. A., Stefansson, G., Isaacson, H., Narita, N., Fukui, A., Ikoma, M., Tamura, M., Kraus, A. L., Furlan, E., Gnilka, C. L., Lester, K. V., and Howell, S. B.
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Astrophysics - Earth and Planetary Astrophysics ,Astrophysics - Astrophysics of Galaxies ,Astrophysics - Solar and Stellar Astrophysics - Abstract
Kepler 1627A is a G8V star previously known to host a 3.8 Earth-radius planet on a 7.2 day orbit. The star was observed by the Kepler space telescope because it is nearby (d=329 pc) and it resembles the Sun. Here we show using Gaia kinematics, TESS stellar rotation periods, and spectroscopic lithium abundances that Kepler 1627 is a member of the 38 $\pm$ 6 Myr old $\delta$ Lyr cluster. To our knowledge, this makes Kepler 1627Ab the youngest planet with a precise age yet found by the prime Kepler mission. The Kepler photometry shows two peculiarities: the average transit profile is asymmetric, and the individual transit times might be correlated with the local light curve slope. We discuss possible explanations for each anomaly. More importantly, the $\delta$ Lyr cluster is one of about 10$^3$ coeval groups whose properties have been clarified by Gaia. Many other exoplanet hosts are candidate members of these clusters; these memberships can be verified with the trifecta of Gaia, TESS, and ground-based spectroscopy., Comment: AJ accepted, Table 3 available upon request
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- 2021
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236. TOI 560 : Two Transiting Planets Orbiting a K Dwarf Validated with iSHELL, PFS and HIRES RVs
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Mufti, Mohammed El, Plavchan, Peter P., Isaacson, Howard, Cale, Bryson L., Feliz, Dax L., Reefe, Michael A., Hellier, Coel, Stassun, Keivan, Eastman, Jason, Polanski, Alex, Crossfield, Ian J. M., Gaidos, Eric, Kostov, Veselin, Villasenor, Joel, Schlieder, Joshua E., Bouma, Luke G., Collins, Kevin I., Wittrock, Justin M., Zohrabi, Farzaneh, Lee, Rena A., Sohani, Ahmad, Berberian, John, Vermilion, David, Newman, Patrick, Geneser, Claire, Tanner, Angelle, Batalha, Natalie M., Dressing, Courtney, Fulton, Benjamin, Howard, Andrew W., Huber, Daniel, Kane, Stephen R., Petigura, Erik A., Robertson, Paul, Roy, Arpita, Weiss, Lauren M., Behmard, Aida, Beard, Corey, Chontos, Ashley, Dai, Fei, Dalba, Paul A., Fetherolf, Tara, Giacalone, Steven, Hill, Michelle L., Hirsch, Lea A., Holcomb, Rae, Lubin, Jack, Mayo, Andrew, Movcnik, Teo, Murphy, Joseph M. Akana, Rosenthal, Lee J., Rubenzahl, Ryan A., Scarsdale, Nicholas, Stockdale, Christopher, Collins, Karen, Cloutier, Ryan, Relles, Howard, Tan, Thiam-Guan, Scott, Nicholas J, Hartman, Zach, Matthews, Elisabeth, Ciardi, David, Gonzales, Erica, Matson, Rachel A., Beichman, Charles, Furlan, E., Gnilka, Crystal L., Howell, Steve B., Ziegler, Carl, Briceno, Cesar, Law, Nicholas, Mann, Andrew W., Rabus, Markus, Johnson, Marshall C., Christiansen, Jessie, Kreidberg, Laura, Berardo, David Anthony, Deming, Drake, Gorjian, Varoujan, Morales, Farisa Y., Benneke, Björn, Dragomir, Diana, Wittenmyer, Robert A., Ballard, Sarah, Bowler, Brendan P., Horner, Jonathan, Kielkopf, John, Liu, Huigen, Shporer, Avi, Tinney, C. G., Zhang, Hui, Wright, Duncan J., Addison, Brett C., Mengel, Matthew W., and Okumura, Jack
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Astrophysics - Earth and Planetary Astrophysics - Abstract
We validate the presence of a two-planet system orbiting the 0.15--1.4 Gyr K4 dwarf TOI 560 (HD 73583). The system consists of an inner moderately eccentric transiting mini-Neptune (TOI 560 b, $P = 6.3980661^{+0.0000095}_{-0.0000097}$ days, $e=0.294^{+0.13}_{-0.062}$, $M= 0.94^{+0.31}_{-0.23}M_{Nep}$) initially discovered in the Sector 8 \tess\ mission observations, and a transiting mini-Neptune (TOI 560 c, $P = 18.8805^{+0.0024}_{-0.0011}$ days, $M= 1.32^{+0.29}_{-0.32}M_{Nep}$) discovered in the Sector 34 observations, in a rare near-1:3 orbital resonance. We utilize photometric data from \tess\, \textit{Spitzer}, and ground-based follow-up observations to confirm the ephemerides and period of the transiting planets, vet false positive scenarios, and detect the photo-eccentric effect for TOI 560 b. We obtain follow-up spectroscopy and corresponding precise radial velocities (RVs) with the iSHELL spectrograph at the NASA Infrared Telescope Facility and the HIRES Spectrograph at Keck Observatory to validate the planetary nature of these signals, which we combine with published PFS RVs from Magellan Observatory. We detect the masses of both planets at $> 3-\sigma$ significance. We apply a Gaussian process (GP) model to the \tess\ light curves to place priors on a chromatic radial velocity GP model to constrain the stellar activity of the TOI 560 host star, and confirm a strong wavelength dependence for the stellar activity demonstrating the ability of NIR RVs in mitigating stellar activity for young K dwarfs. TOI 560 is a nearby moderately young multi-planet system with two planets suitable for atmospheric characterization with James Webb Space Telescope (JWST) and other upcoming missions. In particular, it will undergo six transit pairs separated by $<$6 hours before June 2027., Comment: AAS Journals, Accepted for publication
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- 2021
237. HATS-74Ab, HATS-75b, HATS-76b and HATS-77b: Four Transiting Giant Planets around K and M Dwarfs
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Jordán, A., Hartman, J. D., Bayliss, D., Bakos, G. Á., Brahm, R., Bryant, E. M., Csubry, Z., Henning, Th., Hobson, M., Mancini, L., Penev, K., Rabus, M., Suc, V., de Val-Borro, M., Wallace, J., Barkaoui, K., Ciardi, D. R., Collins, K. A., Esparza-Borges, E., Furlan, E., Gan, T., Ghachoui, M., Gillon, M., Howell, S., Jehin, E., Fukui, A., Kawauchi, K., Livingston, J. H., Luque, R., Matson, R., Matthews, E. C., Osborn, H. P., Murgas, F., Palle, E., and Waalkes, W. C.
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Astrophysics - Earth and Planetary Astrophysics - Abstract
The relative rarity of giant planets around low mass stars compared with solar-type stars is a key prediction from core accretion planet formation theory. In this paper we report on the discovery of four gas giant planets that transit low mass late K and early M dwarfs. The planets HATS-74Ab (TOI 737b), HATS-75b (TOI 552b), HATS-76b (TOI 555b), and HATS-77b (TOI 730b), were all discovered from the HATSouth photometric survey and followed-up using TESS and other photometric facilities. We use the new ESPRESSO facility at the VLT to confirm and systems and measure their masses. We find that that planets have masses of 1.46 +- 0.14 MJ , 0.491 +- 0.039 MJ , 2.629 +- 0.089 MJ and 1.374 +0.100-0.074 MJ , respectively, and radii of 1.032 +- 0.021 RJ , 0.884 +- 0.013 RJ , 1.079 +- 0.031 RJ , and 1.165 +- 0.021 RJ, respectively. The planets all orbit close to their host stars with orbital periods ranging from 1.7319 d to 3.0876 d. With further work we aim to test core accretion theory by using these and further discoveries to quantify the occurrence rate of giant planets around low mass host stars., Comment: Accepted for publication in the Astronomical Journal
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- 2021
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238. TOI-1842b: A Transiting Warm Saturn Undergoing Re-Inflation around an Evolving Subgiant
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Wittenmyer, Robert A., Clark, Jake T., Trifonov, Trifon, Addison, Brett C., Wright, Duncan J., Stassun, Keivan G., Horner, Jonathan, Lowson, Nataliea, Kielkopf, John, Kane, Stephen R., Plavchan, Peter, Shporer, Avi, Zhang, Hui, Bowler, Brendan P., Mengel, Matthew W., Okumura, Jack, Rabus, Markus, Johnson, Marshall C., Harbeck, Daniel, Tronsgaard, Rene, Buchhave, Lars A., Collins, Karen A., Collins, Kevin I., Gan, Tianjun, Jensen, Eric L. N., Howell, Steve B., Furlan, E., Gnilka, Crystal L., Lester, Kathryn V., Matson, Rachel A., Scott, Nicholas J., Ricker, George R., Vanderspek, Roland, Latham, David W., Seager, S., Winn, Joshua N., Jenkins, Jon M., Rudat, Alexander, Quintana, Elisa V., Rodriguez, David R., Caldwell, Douglas A., Quinn, Samuel N., Essack, Zahra, and Bouma, Luke G.
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Astrophysics - Earth and Planetary Astrophysics - Abstract
The imminent launch of space telescopes designed to probe the atmospheres of exoplanets has prompted new efforts to prioritise the thousands of transiting planet candidates for follow-up characterisation. We report the detection and confirmation of TOI-1842b, a warm Saturn identified by TESS and confirmed with ground-based observations from Minerva-Australis, NRES, and the Las Cumbres Observatory Global Telescope. This planet has a radius of $1.04^{+0.06}_{-0.05}\,R_{Jup}$, a mass of $0.214^{+0.040}_{-0.038}\,M_{Jup}$, an orbital period of $9.5739^{+0.0002}_{-0.0001}$ days, and an extremely low density ($\rho$=0.252$\pm$0.091 g cm$^{-3}$). TOI-1842b has among the best known combinations of large atmospheric scale height (893 km) and host-star brightness ($J=8.747$ mag), making it an attractive target for atmospheric characterisation. As the host star is beginning to evolve off the main sequence, TOI-1842b presents an excellent opportunity to test models of gas giant re-inflation. The primary transit duration of only 4.3 hours also makes TOI-1842b an easily-schedulable target for further ground-based atmospheric characterisation., Comment: Accepted for publication in AJ
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- 2021
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239. A multi-planetary system orbiting the early-M dwarf TOI-1238
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González-Álvarez, E., Osorio, M. R. Zapatero, Sanz-Forcada, J., Caballero, J. A., Reffert, S., Béjar, V. J. S., Hatzes, A. P., Herrero, E., Jeffers, S. V., Kemmer, J., López-González, M. J., Luque, R., Molaverdikhani, K., Morello, G., Nagel, E., Quirrenbach, A., Rodríguez, E., Rodríguez-López, C., Schlecker, M., Schweitzer, A., Stock, S., Passegger, V. M., Trifonov, T., Amado, P. J., Baker, D., Boyd, P. T., Cadieux, C., Charbonneau, D., Collins, K. A., Doyon, R., Dreizler, S., Espinoza, N., Furész, G., Furlan, E., Hesse, K., Howell, S. B., Jenkins, J. M., Kidwell, R. C., Latham, D. W., McLeod, K. K., Montes, D., Morales, J. C., O'Dwyer, T., Pallé, E., Pedraz, S., Reiners, A., Ribas, I., Quinn, S. N., Schnaible, C., Seager, S., Skinner, B., Smith, J. C., Schwarz, R. P., Shporer, A., Vanderspek, R., and Winn, J. N.
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Astrophysics - Earth and Planetary Astrophysics - Abstract
Two transiting planet candidates with super-Earth radii around the nearby K7--M0 dwarf star TOI-1238 were announced by TESS. We aim to validate their planetary nature using precise radial velocities (RV) taken with the CARMENES spectrograph. We obtained 55 CARMENES RV data that span 11 months. For a better characterization of the parent star's activity, we also collected contemporaneous optical photometric observations and retrieved archival photometry from the literature. We performed a combined TESS+CARMENES photometric and spectroscopic analysis by including Gaussian processes and Keplerian orbits to account for the stellar activity and planetary signals simultaneously. We estimate that TOI-1238 has a rotation period of 40 $\pm$ 5 d based on photometric and spectroscopic data. The combined analysis confirms the discovery of two transiting planets, TOI-1238 b and c, with orbital periods of $0.764597^{+0.000013}_{-0.000011}$ d and $3.294736^{+0.000034}_{-0.000036}$ d, masses of 3.76$^{+1.15}_{-1.07}$ M$_{\oplus}$ and 8.32$^{+1.90}_{-1.88}$ M$_{\oplus}$, and radii of $1.21^{+0.11}_{-0.10}$ R$_{\oplus}$ and $2.11^{+0.14}_{-0.14}$ R$_{\oplus}$. They orbit their parent star at semimajor axes of 0.0137$\pm$0.0004 au and 0.036$\pm$0.001 au, respectively. The two planets are placed on opposite sides of the radius valley for M dwarfs and lie between the star and the inner border of TOI-1238's habitable zone. The inner super-Earth TOI-1238 b is one of the densest ultra-short-period planets ever discovered ($\rho=11.7^{+4.2}_{-3.4}$ g $\rm cm^{-3}$). The CARMENES data also reveal the presence of an outer, non-transiting, more massive companion with an orbital period and radial velocity amplitude of $\geq$600 d and $\geq$70 m s$^{-1}$, which implies a likely mass of $M \geq 2 \sqrt{1-e^2}$ M$_{\rm Jup}$ and a separation $\geq$1.1 au from its parent star.
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- 2021
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240. TOI-2109b: An Ultrahot Gas Giant on a 16 hr Orbit
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Wong, Ian, Shporer, Avi, Zhou, George, Kitzmann, Daniel, Komacek, Thaddeus D., Tan, Xianyu, Tronsgaard, René, Buchhave, Lars A., Vissapragada, Shreyas, Greklek-McKeon, Michael, Rodriguez, Joseph E., Ahlers, John P., Quinn, Samuel N., Furlan, Elise, Howell, Steve B., Bieryla, Allyson, Heng, Kevin, Knutson, Heather A., Collins, Karen A., McLeod, Kim K., Berlind, Perry, Brown, Peyton, Calkins, Michael L., de Leon, Jerome P., Esparza-Borges, Emma, Esquerdo, Gilbert A., Fukui, Akihiko, Gan, Tianjun, Girardin, Eric, Gnilka, Crystal L., Ikoma, Masahiro, Jensen, Eric L. N., Kielkopf, John, Kodama, Takanori, Kurita, Seiya, Lester, Kathryn V., Lewin, Pablo, Marino, Giuseppe, Murgas, Felipe, Narita, Norio, Pallé, Enric, Schwarz, Richard P., Stassun, Keivan G., Tamura, Motohide, Watanabe, Noriharu, Benneke, Björn, Ricker, George R., Latham, David W., Vanderspek, Roland, Seager, Sara, Winn, Joshua N., Jenkins, Jon M., Caldwell, Douglas A., Fong, William, Huang, Chelsea X., Mireles, Ismael, Schlieder, Joshua E., Shiao, Bernie, and Villaseñor, Jesus Noel
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Astrophysics - Earth and Planetary Astrophysics - Abstract
We report the discovery of an ultrahot Jupiter with an extremely short orbital period of $0.67247414\,\pm\,0.00000028$ days ($\sim$16 hr). The $1.347 \pm 0.047$ $R_{\rm Jup}$ planet, initially identified by the Transiting Exoplanet Survey Satellite (TESS) mission, orbits TOI-2109 (TIC 392476080): a $T_{\rm eff} \sim 6500$ K F-type star with a mass of $1.447 \pm 0.077$ $M_{\rm Sun}$, a radius of $1.698 \pm 0.060$ $R_{\rm Sun}$, and a rotational velocity of $v\sin i_* = 81.9 \pm 1.7$ km s$^{-1}$. The planetary nature of TOI-2109b was confirmed through radial velocity measurements, which yielded a planet mass of $5.02 \pm 0.75$ $M_{\rm Jup}$. Analysis of the Doppler shadow in spectroscopic transit observations indicates a well-aligned system, with a sky-projected obliquity of $\lambda = 1\overset{\circ}{.}7 \pm 1\overset{\circ}{.}7$. From the TESS full-orbit light curve, we measured a secondary eclipse depth of $731 \pm 46$ ppm, as well as phase-curve variations from the planet's longitudinal brightness modulation and ellipsoidal distortion of the host star. Combining the TESS-band occultation measurement with a $K_s$-band secondary eclipse depth ($2012 \pm 80$ ppm) derived from ground-based observations, we find that the dayside emission of TOI-2109b is consistent with a brightness temperature of $3631 \pm 69$ K, making it the second hottest exoplanet hitherto discovered. By virtue of its extreme irradiation and strong planet-star gravitational interaction, TOI-2109b is an exceptionally promising target for intensive follow-up studies using current and near-future telescope facilities to probe for orbital decay, detect tidally driven atmospheric escape, and assess the impacts of H$_2$ dissociation and recombination on the global heat transport., Comment: 30 pages, 17 figures, published in AJ
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- 2021
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241. The VLA/ALMA Nascent Disk and Multiplicity (VANDAM) Survey of Orion Protostars V. A Characterization of Protostellar Multiplicity
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Tobin, John J., Offner, Stella S. R., Kratter, Kaitlin M., Megeath, S. Thomas, Sheehan, Patrick D., Looney, Leslie W., Diaz-Rodriguez, Ana Karla, Osorio, Mayra, Anglada, Guillem, Sadavoy, Sarah I., Furlan, Elise, Segura-Cox, Dominique, Karnath, Nicole, Hoff, Merel L. R. van 't, van Dishoeck, Ewine F., Li, Zhi-Yun, Sharma, Rajeeb, Stutz, Amelia M., and Tychoniec, Lukasz
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Astrophysics - Astrophysics of Galaxies ,Astrophysics - Solar and Stellar Astrophysics - Abstract
We characterize protostellar multiplicity in the Orion molecular clouds using ALMA 0.87~mm and VLA 9~mm continuum surveys toward 328 protostars. These observations are sensitive to projected spatial separations as small as $\sim$20~au, and we consider source separations up to 10$^4$~au as potential companions. The overall multiplicity fraction (MF) and companion fraction (CF) for the Orion protostars are 0.30$\pm$0.03 and 0.44$\pm$0.03, respectively, considering separations from 20 to 10$^4$~au. The MFs and CFs are corrected for potential contamination by unassociated young stars using a probabilistic scheme based on the surface density of young stars around each protostar. The companion separation distribution as a whole is double peaked and inconsistent with the separation distribution of solar-type field stars, while the separation distribution of Flat Spectrum protostars is consistent solar-type field stars. The multiplicity statistics and companion separation distributions of the Perseus star-forming region are consistent with those of Orion. Based on the observed peaks in the Class 0 separations at $\sim$100~au and $\sim$10$^3$~au, we argue that multiples with separations $<$500~au are likely produced by both disk fragmentation and turbulent fragmentation with migration, and those at $\ga$10$^3$~au result primarily from turbulent fragmentation. We also find that MFs/CFs may rise from Class 0 to Flat Spectrum protostars between 100 and 10$^3$~au in regions of high YSO density. This finding may be evidence for migration of companions from $>$10$^3$~au to $<$10$^3$~au, and that some companions between 10$^3$ and 10$^4$~au must be (or become) unbound., Comment: 76 pages, 20 Figures, 10 Tables, accepted by the Astrophysical Journal
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- 2021
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242. TOI-712: a system of adolescent mini-Neptunes extending to the habitable zone
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Vach, Sydney, Quinn, Samuel N., Vanderburg, Andrew, Kane, Stephen R., Collins, Karen A., Kraus, Adam L., Zhou, George, Medina, Amber A., Schwarz, Richard P., Collins, Kevin I., Conti, Dennis M., Stockdale, Chris, Massey, Bob, Suarez, Olga, Guillot, Tristan, Mekarnia, Djamel, Abe, Lyu, Dransfield, Georgina, Crouzet, Nicolas, Triaud, Amaury H. M. J., Schmider, François-Xavier, Agabi, Abelkrim, Buttu, Marco, Furlan, Elise, Gnilka, Crystal L., Howell, Steve B., Ziegler, Carl, Briceño, César, Law, Nicholas, Mann, Andrew W., Rudat, Alexander, Colon, Knicole D., Rose, Mark E., Kunimoto, Michelle, Günther, Maximilian N., Charbonneau, David, Ciardi, David R., Ricker, George R., Vanderspek, Roland K., Latham, David W., Seager, Sara, Winn, Joshua N., and Jenkins, Jon M.
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Astrophysics - Earth and Planetary Astrophysics - Abstract
As an all-sky survey, NASA's $TESS$ mission is able to detect the brightest and rarest types of transiting planetary systems, including young planets that enable study of the evolutionary processes that occur within the first billion years. Here, we report the discovery of a young, multi-planet system orbiting the bright K4.5V star, TOI-712 ($V = 10.838$, $M_\star = 0.733_{-0.025}^{+0.026} M_\odot$, $R_\star = 0.674\pm0.016 R_\odot$, $T_{\rm eff} = 4622_{-60}^{+61}$ K). From the $TESS$ light curve, we measure a rotation period of 12.48 days, and derive an age between about $500$ Myr and 1.1 Gyr. The photometric observations reveal three transiting mini-Neptunes ($R_b = 2.049^{+0.12}_{-0.080} R_\oplus$, $R_c = 2.701^{+0.092}_{-0.082} R_\oplus$, $R_d = 2.474^{+0.090}_{-0.082} R_\oplus $), with orbital periods of $P_b = 9.531$ days, $P_c = 51.699$ days, and $P_d = 84.839$ days. After modeling the three-planet system, an additional Earth-sized candidate is identified, TOI-712.05 ($P = 4.32$ days, $R_P = 0.81 \pm 0.11 R_\oplus$). We calculate that the habitable zone falls between 0.339 and 0.844 au (82.7 and 325.3 days), placing TOI-712 d near its inner edge. Among planetary systems harboring temperate planets, TOI-712 ($T = 9.9$) stands out as a relatively young star bright enough to motivate further characterization., Comment: 20 pages, 11 figures, 5 tables, submitted to AAS Journals
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- 2021
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243. TOI-2257 b: A highly eccentric long-period sub-Neptune transiting a nearby M dwarf
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Schanche, N., Pozuelos, F. J., Günther, M. N., Wells, R. D., Burgasser, A. J., Chinchilla, P., Delrez, L., Ducrot, E., Garcia, L. J., Chew, Y. Gómez Maqueo, Jofré, E., Rackham, B. V., Sebastian, D., Stassun, K. G., Stern, D., Timmermans, M., Barkaoui, K., Belinski, A., Benkhaldoun, Z., Benz, W., Charbonneau, D., Christiansen, Jessie L., Collins, Karen A., Demory, B. -O., Dévora-Pajares, M., de Wit, J., Dragomir, D., Dransfield, G., Furlan, E., Ghachou, M., Gillon, M., Gnilka, C., Gómez-Muñoz, M. A., Guerrero, N., Harris, M., Heng, K., Henze, C. E., Hesse, K., Howell, S. B., Jehin, E., Jenkins, J., Jensen, Eric L. N., Kunimoto, M., Latham, D. W., Lester, K., McLeod, Kim K., Mireles, I., Murray, C. A., Niraula, P., Pedersen, P. P., Queloz, D., Quintana, E. V., Ricker, G., Rudat, A., Sabin, L., Safonov, B., Schroffenegger, U., Scott, N., Seager, S., Strakhov, I., Triaud, A. H. M. J., Vanderspek, R., Vezie, M., and Winn, J.
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Astrophysics - Earth and Planetary Astrophysics - Abstract
Thanks to the relative ease of finding and characterizing small planets around M dwarf stars, these objects have become cornerstones in the field of exoplanet studies. The current paucity of planets in long-period orbits around M dwarfs make such objects particularly compelling as they provide clues about the formation and evolution of these systems. In this study, we present the discovery of TOI-2257 b (TIC 198485881), a long-period (35 d) sub-Neptune orbiting an M3 star at 57.8pc. Its transit depth is about 0.4%, large enough to be detected with medium-size, ground-based telescopes. The long transit duration suggests the planet is in a highly eccentric orbit ($e \sim 0.5$), which would make it the most eccentric planet that is known to be transiting an M-dwarf star. We combined TESS and ground-based data obtained with the 1.0-m SAINT-EX, 0.60-m TRAPPIST-North and 1.2-m FLWO telescopes to find a planetary size of 2.2 $R_{\oplus}$ and an orbital period of 35.19 days. In addition, we make use of archival data, high-resolution imaging, and vetting packages to support our planetary interpretation. With its long period and high eccentricity, TOI-2257 b falls in a novel slice of parameter space. Despite the planet's low equilibrium temperature ($\sim$ 256 K), its host star's small size ($R_* = 0.311 \pm{0.015}$) and relative infrared brightness (K$_{mag}$ = 10.7) make it a suitable candidate for atmospheric exploration via transmission spectroscopy., Comment: 18 pages, 12 figures, 2 appendices, Accepted for publication in Astronomy and Astrophysics
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- 2021
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244. TOI-2076 and TOI-1807: Two young, comoving planetary systems within 50 pc identified by TESS that are ideal candidates for further follow-up
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Hedges, Christina, Hughes, Alex, Giacalone, Steven, Zhou, George, David, Trevor J., Becker, Juliette, Vanderburg, Andrew, Rodriguez, Joseph E., Atherton, Shaun, Quinn, Samueln., Dressing, Courtney D., Bieryla, Allyson, Fetherolf, Tara, Price-whelan, Adrian, Bedell, Megan, Latham, David W., Ricker, Georger., Vanderspek, Roland K., Seager, Sara, Winn, Joshua N., Jenkins, Jon M., Tronsgaard, Rene, Buchhave, Lars A., Collins, Karen A., Gan, Tianjun, Jensen, Eric L. N., Kielkopf, John F., Schwarz, Richard P., Gonzales, Erica J., Crossfield, Ian J. M., Furlan, E., Gnilka, Crysta Ll., Howell, Steve B., Lester, Kathryn V., Scott, Nicholas J., Feliz, Dax L., Lund, Michael B., Siverd, Robert J., Stevens, Daniel J., Narita, N., Fukui, A., Murgas, F., Palle, Enric, Sutton, Phil, and Stassun, Keivan G.
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Astrophysics - Earth and Planetary Astrophysics ,Astrophysics - Instrumentation and Methods for Astrophysics - Abstract
We report the discovery of two planetary systems around comoving stars; TOI-2076 (TIC 27491137) and TOI-1807 (TIC 180695581). TOI-2076 is a nearby (41.9 pc) multi-planetary system orbiting a young (204$\pm$50 Myr), bright (K = 7.115 in TIC v8.1). TOI-1807 hosts a single transiting planet, and is similarly nearby (42.58pc), similarly young (180$\pm$40 Myr), and bright. Both targets exhibit significant, periodic variability due to star spots, characteristic of their young ages. Using photometric data collected by TESS we identify three transiting planets around TOI-2076 with radii of R$_b$=3.3$\pm$0.04$R_\oplus$, R$_c$=4.4$\pm$0.05$R_\oplus$, and R$_d$=4.1$\pm$0.07$R_\oplus$. Planet TOI-2076b has a period of P$_b$=10.356 d. For both TOI 2076c and d, TESS observed only two transits, separated by a 2-year interval in which no data were collected, preventing a unique period determination. A range of long periods (>17d) are consistent with the data. We identify a short-period planet around TOI-1807 with a radius of R$_b$=1.8$\pm$0.04$R_\oplus$ and a period of P$_b$=0.549 d. Their close proximity, and bright, cool host stars, and young ages, make these planets excellent candidates for follow-up. TOI-1807b is one of the best known small ($R<2R_\oplus$) planets for characterization via eclipse spectroscopy and phase curves with JWST. TOI-1807b is the youngest ultra-short period planet discovered to date, providing valuable constraints on formation time-scales of short period planets. Given the rarity of young planets, particularly in multiple planet systems, these planets present an unprecedented opportunity to study and compare exoplanet formation, and young planet atmospheres, at a crucial transition age for formation theory., Comment: 27 pages, 13 figures, 6 tables
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- 2021
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245. The young HD 73583 (TOI-560) planetary system: Two 10-M$_\oplus$ mini-Neptunes transiting a 500-Myr-old, bright, and active K dwarf
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Barragán, O., Armstrong, D. J., Gandolfi, D., Carleo, I., Vidotto, A. A., D'Angelo, C. Villarreal, Oklopčić, A., Isaacson, H., Oddo, D., Collins, K., Fridlund, M., Sousa, S. G., Persson, C. M., Hellier, C., Howell, S., Howard, A., Redfield, S., Eisner, N., Georgieva, I. Y., Dragomir, D., Bayliss, D., Nielsen, L. D., Klein, B., Aigrain, S., Zhang, M., Teske, J., Twicken, J D., Jenkins, J., Esposito, M., Van Eylen, V., Rodler, F., Adibekyan, V., Alarcon, J., Anderson, D. R., Murphy, J. M. Akana, Barrado, D., Barros, S. C. C., Benneke, B., Bouchy, F., Bryant, E. M., Butler, P., Burt, J., Cabrera, J., Casewell, S., Chaturvedi, P., Cloutier, R., Cochran, W. D., Crane, J., Crossfield, I., Crouzet, N., Collins, K. I., Dai, F., Deeg, H. J., Deline, A., Demangeon, O. D. S., Dumusque, X., Figueira, P., Furlan, E., Gnilka, C., Goad, M. R., Goffo, E., Gutiérrez-Canales, F., Hadjigeorghiou, A., Hartman, Z., Hatzes, A. P., Harris, M., Henderson, B., Hirano, T., Hojjatpanah, S., Hoyer, S., Kabáth, P., Korth, J., Lillo-Box, J., Luque, R., Marmier, M., Močnik, T., Muresan, A., Murgas, F., Nagel, E., Osborne, H. L. M., Osborn, A., Osborn, H. P., Palle, E., Raimbault, M., Ricker, G. R., Rubenzahl, R A., Stockdale, C., Santos, N. C., Scott, N., Schwarz, R. P., Shectman, S., Seager, S., Ségransan, D., Serrano, L. M., Skarka, M., Smith, A. M. S., Šubjak, J., Tan, T. G., Udry, S., Watson, C., Wheatley, P. J., West, R., Winn, J. N., Wang, S. X., Wolfgang, A., and Ziegler, C.
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Astrophysics - Earth and Planetary Astrophysics ,Astrophysics - Solar and Stellar Astrophysics - Abstract
We present the discovery and characterisation of two transiting planets observed by \textit{TESS} in the light curves of the young and bright (V=9.67) star HD73583 (TOI-560). We perform an intensive spectroscopic and photometric space- and ground-based follow-up in order to confirm and characterise the system. We found that HD73583 is a young ($\sim 500$~Myr) active star with a rotational period of $12.08 \pm 0.11 $\,d, and a mass and radius of $ 0.73 \pm 0.02 M_\odot$ and $0.65 \pm 0.02 R_\odot$, respectively. HD73583 b ($P_b=6.3980420 _{ - 0.0000062 }^{+0.0000067}$ d) has a mass and radius of $10.2 _{-3.1}^{+3.4} M_\oplus$ and$2.79 \pm 0.10 R_\oplus$, respectively, that gives a density of $2.58 _{-0.81}^{ 0.95} {\rm g\,cm^{-3}}$. HD73583 c ($P_c= 18.87974 _{-0.00074 }^{+0.00086}$) has a mass and radius of $9.7_{-1.7} ^ {+1.8} M_\oplus$ and $2.39_{-0.09}^{+0.10} R_\oplus$, respectively, this translates to a density of $3.88 _{-0.80}^{+0.91} {\rm g\,cm^{-3}}$. Both planets are consistent with worlds made of a solid core surrounded by a volatile envelope. Because of their youth and host star brightness, they both are excellent candidates to perform transmission spectroscopy studies. We expect ongoing atmospheric mass-loss for both planets caused by stellar irradiation. We estimate that the detection of evaporating signatures on H and He would be challenging, but doable with present and future instruments., Comment: Accepted for publication in MNRAS
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- 2021
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246. TESS Hunt for Young and Maturing Exoplanets (THYME) VI: an 11 Myr giant planet transiting a very low-mass star in Lower Centaurus Crux
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Mann, Andrew W., Wood, Mackenna L., Schmidt, Stephen P., Barber, Madyson G., Owen, James E., Tofflemire, Benjamin M., Newton, Elisabeth R., Mamajek, Eric E., Bush, Jonathan L., Mace, Gregory N., Kraus, Adam L., Thao, Pa Chia, Vanderburg, Andrew, Llama, Joe, Johns-Krull, Christopher M., Prato, L., Stahl, Asa G., Tang, Shih-Yun, Fields, Matthew J., Collins, Karen A., Collins, Kevin I., Gan, Tianjun, Jensen, Eric L. N., Kamler, Jacob, Schwarz, Richard P., Furlan, Elise, Gnilka, Crystal L., Howell, Steve B., Lester, Kathryn V., Owens, Dylan A., Suarez, Olga, Mekarnia, Djamel, Guillot, Tristan, Abe, Lyu, Triaud, Amaury H. M. J., Johnson, Marshall C., Milburn, Reilly P., Rizzuto, Aaron C., Quinn, Samuel N., Kerr, Ronan, Ricker, George R., Vanderspek, Roland, Latham, David W., Seager, Sara, Winn, Joshua N., Jenkins, Jon M., Guerrero, Natalia M., Shporer, Avi, Schlieder, Joshua E., McLean, Brian, and Wohler, Bill
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Astrophysics - Earth and Planetary Astrophysics ,Astrophysics - Solar and Stellar Astrophysics - Abstract
Mature super-Earths and sub-Neptunes are predicted to be $\simeq$Jovian radius when younger than 10 Myr. Thus, we expect to find 5-15$R_\oplus$ planets around young stars even if their older counterparts harbor none. We report the discovery and validation of TOI 1227 b, a $0.85\pm0.05R_J$ (9.5$R_\oplus$) planet transiting a very low-mass star ($0.170\pm0.015M_\odot$) every 27.4 days. TOI~1227's kinematics and strong lithium absorption confirm it is a member of a previously discovered sub-group in the Lower Centaurus Crux OB association, which we designate the Musca group. We derive an age of 11$\pm$2 Myr for Musca, based on lithium, rotation, and the color-magnitude diagram of Musca members. The TESS data and ground-based follow-up show a deep (2.5\%) transit. We use multiwavelength transit observations and radial velocities from the IGRINS spectrograph to validate the signal as planetary in nature, and we obtain an upper limit on the planet mass of $\simeq0.5 M_J$. Because such large planets are exceptionally rare around mature low-mass stars, we suggest that TOI 1227 b is still contracting and will eventually turn into one of the more common $<5R_\oplus$ planets., Comment: Accepted to the Astronomical Journal. Minor updates during referee process and proofs
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- 2021
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247. Pera orange juice (Citrus sinensis L. Osbeck) alters lipid metabolism and attenuates oxidative stress in the heart and liver of rats treated with doxorubicin
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Cabral, Ronny Peterson, Ribeiro, Ana Paula Dantas, Monte, Marina Gaiato, Fujimori, Anderson Seiji Soares, Tonon, Carolina Rodrigues, Ferreira, Natalia Fernanda, Zanatti, Silmeia Garcia, Minicucci, Marcos Ferreira, Zornoff, Leonardo Antonio Mamede, Paiva, Sergio Alberto Rupp de, and Polegato, Bertha Furlan
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- 2024
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248. HA-1–targeted T-cell receptor T-cell therapy for recurrent leukemia after hematopoietic stem cell transplantation
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Krakow, Elizabeth F., Brault, Michelle, Summers, Corinne, Cunningham, Tanya M., Biernacki, Melinda A., Black, R. Graeme, Woodward, Kyle B., Vartanian, Nicole, Kanaan, Sami B., Yeh, Albert C., Dossa, Robson G., Bar, Merav, Cassaday, Ryan D., Dahlberg, Ann, Till, Brian G., Denker, Andrew E., Yeung, Cecilia C. S., Gooley, Ted A., Maloney, David G., Riddell, Stanley R., Greenberg, Philip D., Chapuis, Aude G., Newell, Evan W., Furlan, Scott N., and Bleakley, Marie
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- 2024
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249. Improving Prostate MR Image Quality in Practice—Initial Results From the ACR Prostate MR Image Quality Improvement Collaborative
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Weinreb, Jeffrey, Tempany, Clare, Smith, Christopher, Hester, Ann, Chang, Kevin, Martin, Sara, Gupta, Rajan, Owenby, Erica, McLean, Logan, Campbell, Linda, Furlan, Alessandro, Grills, Andrew, Purysko, Andrei S., Zacharias-Andrews, Kay, Tomkins, Kandice Garcia, Turkbey, Ismail Baris, Giganti, Francesco, Bhargavan-Chatfield, Mythreyi, and Larson, David B.
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- 2024
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250. Screening and risk assessment for sleep-related breathing disorders in individuals living with spinal cord injury
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Furlan, Julio C., Hitzig, Sander L., Milligan, James, Athanasopoulos, Peter, and Boulos, Mark I.
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- 2024
- Full Text
- View/download PDF
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