201. Describing symptoms using the Symptom Screening in Pediatrics Tool in hospitalized children with cancer and hematopoietic stem cell transplant recipients
- Author
-
Brenda J. Spiegler, Carol Portwine, Magimairajan Issai Vanan, Andrea D. Orsey, Paul Gibson, Deborah Tomlinson, Laura Lee Dupuis, George Tomlinson, David Dix, Christina Baggott, Shannon Hyslop, Lillian Sung, Susan Kuczynski, Donna L. Johnston, and Vicky Price
- Subjects
Male ,Canada ,Cancer Research ,Pediatrics ,medicine.medical_specialty ,Future studies ,Adolescent ,Adolescent, Hospitalized ,Psychometrics ,medicine.medical_treatment ,Psychological intervention ,Hematopoietic stem cell transplantation ,03 medical and health sciences ,0302 clinical medicine ,Neoplasms ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,030212 general & internal medicine ,symptom screening ,Child ,Children ,Early Detection of Cancer ,Original Research ,business.industry ,Hematopoietic Stem Cell Transplantation ,Clinical Cancer Research ,Cancer ,RELAPSED DISEASE ,Odds ratio ,medicine.disease ,United States ,Confidence interval ,Logistic Models ,Oncology ,030220 oncology & carcinogenesis ,Female ,Self Report ,Active treatment ,Symptom Assessment ,business ,Child, Hospitalized - Abstract
Objectives were to describe any bothersome symptom and severely bothersome symptoms in inpatient children with cancer and hematopoietic stem cell transplant (HSCT) recipients. We included children 8–18 years of age with cancer or HSCT recipients who were receiving active treatment for cancer, admitted to hospital, and expected to be in hospital 3 days later. We administered the self‐report Symptom Screening in Pediatrics Tool (SSPedi). We described those who identified any degree of symptom bother (at least “a little”) and those who rated the degree of bother as severe (“a lot” or “extremely”). Factors associated with severe symptoms and total SSPedi scores were examined using multiple logistic and linear regression. Among the 302 patients, 298 (98.7%) reported having any bothersome symptom and 181 (59.9%) had at least one severely bothersome symptom. In multiple regression, older children were significantly more likely to have at least one severely bothersome symptom (15–18 and 11–14 years vs. 8–10 years; P = 0.008) and to have higher total SSPedi scores (P = 0.0003). Those with relapsed disease were more likely to have at least one severely bothersome symptom (odds ratio 2.1, 95% confidence interval 1.1–4.3; P = 0.037) and HSCT recipients were more likely to have higher symptom scores (β = 3.48, standard error = 1.6; P = 0.030). Almost all children receiving cancer therapies experience bothersome symptoms and 60% have at least one severely bothersome symptom. Older children experienced more severely bothersome symptoms and higher symptom scores. Future studies should follow children longitudinally to better understand the symptom trajectory and should institute interventions to manage symptoms.
- Published
- 2018