8,332 results on '"Gonzalez A. E."'
Search Results
202. Effects of Memantine on the Auditory Steady-State and Harmonic Responses to 40 Hz Stimulation Across Species
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Swerdlow, Neal R., Gonzalez, Christopher E., Raza, Muhammad Ummear, Gautam, Deepshila, Miyakoshi, Makoto, Clayson, Peter E., Joshi, Yash B., Molina, Juan L., Talledo, Jo, Thomas, Michael L., Light, Gregory A., and Sivarao, Digavalli V.
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- 2024
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203. Regulation of EZH2 protein stability: new mechanisms, roles in tumorigenesis, and roads to the clinic
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Guo, Yunyun, Cheng, Rui, Wang, Yuqing, Gonzalez, Maria E., Zhang, Hongshan, Liu, Yang, Kleer, Celina G., and Xue, Lixiang
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- 2024
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204. [Translated article] Cost of Treating Cutaneous T-Cell Lymphoma in Spain: Analysis of MICADOS Study Data by Disease Stage
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Navarro Matilla, B., Ortiz Romero, P.L., Pujol Vallverdú, R.M., Combalia Escudero, A., Zapata Paz, I., González Barca, E., Muniesa Montserrat, C., Morillo Andújar, M., Pérez Ferriols, A., Román Curto, C., Fernández de Misa Cabrera, R., Hospital Gil, M., Marín Niebla, A., Rios Rull, P.J., de la Cruz Vicente, F., Izu Belloso, R.M., Martín García-Sancho, A., Parera Amer, M.E., Córdoba Mascuñano, R., Ramón Quiles, M.D., Saus Carreres, A., del Campo García, R., Machan, S., Viguera Ester, P., and Blanco Garnelo, J.
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- 2024
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205. Side-polished photonic crystal fiber sensor with ultra-high figure of merit based on Bloch-like surface wave resonance
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Gonzalez-Valencia, E., Reyes-Vera, E., Del Villar, I., and Torres, Pedro
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- 2024
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206. Evaluación de los costes asociados a la enfermedad de pacientes con linfoma cutáneo de células T en España: análisis en función del estadio clínico (estudio MICADOS)
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Navarro Matilla, B., Ortiz Romero, P.L., Pujol Vallverdú, R.M., Combalia Escudero, A., Zapata Paz, I., González Barca, E., Muniesa Montserrat, C., Morillo Andújar, M., Pérez Ferriols, A., Román Curto, C., Fernández de Misa Cabrera, R., Hospital Gil, M., Marín Niebla, A., Rios Rull, P.J., de la Cruz Vicente, F., Izu Belloso, R.M., Martín García-Sancho, A., Parera Amer, M.E., Córdoba Mascuñano, R., Ramón Quiles, M.D., Saus Carreres, A., del Campo García, R., Machan, S., Viguera Ester, P., and Blanco Garnelo, J.
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- 2024
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207. An in vivo Cell-Based Delivery Platform for Zinc Finger Artificial Transcription Factors in Pre-clinical Animal Models
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Deng, Peter, Halmai, Julian ANM, Beitnere, Ulrika, Cameron, David, Martinez, Michele L, Lee, Charles C, Waldo, Jennifer J, Thongphanh, Krista, Adhikari, Anna, Copping, Nycole, Petkova, Stela P, Lee, Ruth D, Lock, Samantha, Palomares, Miranda, O’Geen, Henriette, Carter, Jasmine, Gonzalez, Casiana E, Buchanan, Fiona KB, Anderson, Johnathan D, Fierro, Fernando A, Nolta, Jan A, Tarantal, Alice F, Silverman, Jill L, Segal, David J, and Fink, Kyle D
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Medical Biotechnology ,Biomedical and Clinical Sciences ,Rare Diseases ,Biotechnology ,Brain Disorders ,Genetics ,Stem Cell Research - Nonembryonic - Non-Human ,Neurosciences ,Stem Cell Research ,5.2 Cellular and gene therapies ,zinc finger ,Angelman Syndrome ,mesenchymal stem ,stromal cell ,artificial transcription factor ,cell-based delivery ,mesenchymal stem/stromal cell ,Clinical Sciences ,Biochemistry and cell biology ,Biological psychology - Abstract
Zinc finger (ZF), transcription activator-like effectors (TALE), and CRISPR/Cas9 therapies to regulate gene expression are becoming viable strategies to treat genetic disorders, although effective in vivo delivery systems for these proteins remain a major translational hurdle. We describe the use of a mesenchymal stem/stromal cell (MSC)-based delivery system for the secretion of a ZF protein (ZF-MSC) in transgenic mouse models and young rhesus monkeys. Secreted ZF protein from mouse ZF-MSC was detectable within the hippocampus 1 week following intracranial or cisterna magna (CM) injection. Secreted ZF activated the imprinted paternal Ube3a in a transgenic reporter mouse and ameliorated motor deficits in a Ube3a deletion Angelman Syndrome (AS) mouse. Intrathecally administered autologous rhesus MSCs were well-tolerated for 3 weeks following administration and secreted ZF protein was detectable within the cerebrospinal fluid (CSF), midbrain, and spinal cord. This approach is less invasive when compared to direct intracranial injection which requires a surgical procedure.
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- 2022
208. Finite-temperature critical behavior of long-range quantum Ising models
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Gonzalez-Lazo, E., Heyl, M., Dalmonte, M., and Angelone, A.
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Condensed Matter - Statistical Mechanics - Abstract
We study the phase diagram and critical properties of quantum Ising chains with long-range ferromagnetic interactions decaying in a power-law fashion with exponent $\alpha$, in regimes of direct interest for current trapped ion experiments. Using large-scale path integral Monte Carlo simulations, we investigate both the ground-state and the nonzero-temperature regimes. We identify the phase boundary of the ferromagnetic phase and obtain accurate estimates for the ferromagnetic-paramagnetic transition temperatures. We further determine the critical exponents of the respective transitions. Our results are in agreement with existing predictions for interaction exponents $\alpha > 1$ up to small deviations in some critical exponents. We also address the elusive regime $\alpha < 1$, where we find that the universality class of both the ground-state and nonzero-temperature transition is consistent with the mean-field limit at $\alpha = 0$. Our work not only contributes to the understanding of the equilibrium properties of long-range interacting quantum Ising models, but can also be important for addressing fundamental dynamical aspects, such as issues concerning the open question of thermalization in such models., Comment: 19 pages, 6 figures, updated to follow minor revisions suggested by the referees
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- 2021
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209. ActNN: Reducing Training Memory Footprint via 2-Bit Activation Compressed Training
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Chen, Jianfei, Zheng, Lianmin, Yao, Zhewei, Wang, Dequan, Stoica, Ion, Mahoney, Michael W., and Gonzalez, Joseph E.
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Computer Science - Machine Learning ,Computer Science - Computer Vision and Pattern Recognition ,Statistics - Machine Learning - Abstract
The increasing size of neural network models has been critical for improvements in their accuracy, but device memory is not growing at the same rate. This creates fundamental challenges for training neural networks within limited memory environments. In this work, we propose ActNN, a memory-efficient training framework that stores randomly quantized activations for back propagation. We prove the convergence of ActNN for general network architectures, and we characterize the impact of quantization on the convergence via an exact expression for the gradient variance. Using our theory, we propose novel mixed-precision quantization strategies that exploit the activation's heterogeneity across feature dimensions, samples, and layers. These techniques can be readily applied to existing dynamic graph frameworks, such as PyTorch, simply by substituting the layers. We evaluate ActNN on mainstream computer vision models for classification, detection, and segmentation tasks. On all these tasks, ActNN compresses the activation to 2 bits on average, with negligible accuracy loss. ActNN reduces the memory footprint of the activation by 12x, and it enables training with a 6.6x to 14x larger batch size., Comment: to be published in ICML 2021
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- 2021
210. Testing the consistency between cosmological data: the impact of spatial curvature and the dark energy EoS
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Gonzalez, Javier E., Benetti, Micol, von Marttens, Rodrigo, and Alcaniz, Jailson
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Astrophysics - Cosmology and Nongalactic Astrophysics - Abstract
The results of joint analyses of available cosmological data have motivated an important debate about a possible detection of a non-zero spatial curvature. If confirmed, such a result would imply a change in our present understanding of cosmic evolution with important theoretical and observational consequences. In this paper we discuss the legitimacy of carrying out joint analyses with the currently available data sets and explore their implications for a non-flat universe and extensions of the standard cosmological model. We use a robust tension estimator to perform a quantitative analysis of the physical consistency between the latest data of Cosmic Microwave Background, type Ia supernovae, Baryonic Acoustic Oscillations and Cosmic Chronometers. We consider the flat and non-flat cases of the $\Lambda$CDM cosmology and of two dark energy models with a constant and varying dark energy EoS parameter. The present study allows us to better understand if possible inconsistencies between these data sets are significant enough to make the results of their joint analyses misleading, as well as the actual dependence of such results with the spatial curvature and dark energy parameterizations., Comment: 11 pages, 6 figures, 1 table
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- 2021
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211. Contingencies from Observations: Tractable Contingency Planning with Learned Behavior Models
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Rhinehart, Nicholas, He, Jeff, Packer, Charles, Wright, Matthew A., McAllister, Rowan, Gonzalez, Joseph E., and Levine, Sergey
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Computer Science - Robotics ,Computer Science - Computer Vision and Pattern Recognition ,Computer Science - Machine Learning - Abstract
Humans have a remarkable ability to make decisions by accurately reasoning about future events, including the future behaviors and states of mind of other agents. Consider driving a car through a busy intersection: it is necessary to reason about the physics of the vehicle, the intentions of other drivers, and their beliefs about your own intentions. If you signal a turn, another driver might yield to you, or if you enter the passing lane, another driver might decelerate to give you room to merge in front. Competent drivers must plan how they can safely react to a variety of potential future behaviors of other agents before they make their next move. This requires contingency planning: explicitly planning a set of conditional actions that depend on the stochastic outcome of future events. In this work, we develop a general-purpose contingency planner that is learned end-to-end using high-dimensional scene observations and low-dimensional behavioral observations. We use a conditional autoregressive flow model to create a compact contingency planning space, and show how this model can tractably learn contingencies from behavioral observations. We developed a closed-loop control benchmark of realistic multi-agent scenarios in a driving simulator (CARLA), on which we compare our method to various noncontingent methods that reason about multi-agent future behavior, including several state-of-the-art deep learning-based planning approaches. We illustrate that these noncontingent planning methods fundamentally fail on this benchmark, and find that our deep contingency planning method achieves significantly superior performance. Code to run our benchmark and reproduce our results is available at https://sites.google.com/view/contingency-planning, Comment: To be published at ICRA 2021. Project page: https://sites.google.com/view/contingency-planning
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- 2021
212. Data-Efficient Language-Supervised Zero-Shot Learning with Self-Distillation
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Cheng, Ruizhe, Wu, Bichen, Zhang, Peizhao, Vajda, Peter, and Gonzalez, Joseph E.
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Computer Science - Computer Vision and Pattern Recognition - Abstract
Traditional computer vision models are trained to predict a fixed set of predefined categories. Recently, natural language has been shown to be a broader and richer source of supervision that provides finer descriptions to visual concepts than supervised "gold" labels. Previous works, such as CLIP, use a simple pretraining task of predicting the pairings between images and text captions. CLIP, however, is data hungry and requires more than 400M image text pairs for training. We propose a data-efficient contrastive distillation method that uses soft labels to learn from noisy image-text pairs. Our model transfers knowledge from pretrained image and sentence encoders and achieves strong performance with only 3M image text pairs, 133x smaller than CLIP. Our method exceeds the previous SoTA of general zero-shot learning on ImageNet 21k+1k by 73% relatively with a ResNet50 image encoder and DeCLUTR text encoder. We also beat CLIP by 10.5% relatively on zero-shot evaluation on Google Open Images (19,958 classes)., Comment: 4 pages, 1 figure
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- 2021
213. Robust Object Detection via Instance-Level Temporal Cycle Confusion
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Wang, Xin, Huang, Thomas E., Liu, Benlin, Yu, Fisher, Wang, Xiaolong, Gonzalez, Joseph E., and Darrell, Trevor
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Computer Science - Computer Vision and Pattern Recognition - Abstract
Building reliable object detectors that are robust to domain shifts, such as various changes in context, viewpoint, and object appearances, is critical for real-world applications. In this work, we study the effectiveness of auxiliary self-supervised tasks to improve the out-of-distribution generalization of object detectors. Inspired by the principle of maximum entropy, we introduce a novel self-supervised task, instance-level temporal cycle confusion (CycConf), which operates on the region features of the object detectors. For each object, the task is to find the most different object proposals in the adjacent frame in a video and then cycle back to itself for self-supervision. CycConf encourages the object detector to explore invariant structures across instances under various motions, which leads to improved model robustness in unseen domains at test time. We observe consistent out-of-domain performance improvements when training object detectors in tandem with self-supervised tasks on large-scale video datasets (BDD100K and Waymo open data). The joint training framework also establishes a new state-of-the-art on standard unsupervised domain adaptative detection benchmarks (Cityscapes, Foggy Cityscapes, and Sim10K). The code and models are available at https://github.com/xinw1012/cycle-confusion., Comment: ICCV 2021
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- 2021
214. Are local ULIRGs powered by AGN? The sub-kpc view of the 220 GHz continuum. PUMA II
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Pereira-Santaella, M., Colina, L., García-Burillo, S., Lamperti, I., González-Alfonso, E., Perna, M., Arribas, S., Alonso-Herrero, A., Aalto, S., Combes, F., Labiano, A., Piqueras-López, J., Rigopoulou, D., and van der Werf, P.
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Astrophysics - Astrophysics of Galaxies - Abstract
We analyze high-resolution (400pc) 220GHz continuum and CO(2-1) ALMA observations of a representative sample of 23 local (z<0.165) ULIRG systems (34 individual nuclei) as part of the "Physics of ULIRGs with MUSE and ALMA" (PUMA) project. The deconvolved half-light radii of the 220GHz continuum sources are between <60-350 pc (median 90pc). We associate these regions with the regions emitting the bulk of the infrared luminosity. The good agreement, within a factor of 2, between the 220GHz fluxes and the extrapolation of the infrared gray-body, and the small synchrotron and free-free contributions support this assumption. The cold molecular gas emission sizes, r_CO, are 60-700 pc and are similar in advanced mergers and early interacting systems. On average, r_CO are 2.5 times larger than the continuum. We derive L_IR and cold molecular gas surface densities: log Sigma(L_IR)=11.5-14.3 Lsun/kpc^2 and log Sigma(H2)=2.9-4.2 Msun/pc^2. Assuming that the L_IR is produced by star-formation, this corresponds to median Sigma(SFR)=2500 Msun/yr/kpc^2 which would imply extremely short depletion times, <1-15 Myr, and unphysical SF efficiencies >1 for 70% of the sample. Therefore, this favors the presence of obscured AGN that could dominate the L_IR. We also classify the ULIRG nuclei in two groups: (a) compact nuclei (r<130 pc) with high mid-IR excess emission found in optically classified AGN; and (b) nuclei following a relation with decreasing mid-IR excess for decreasing r. 60% of the interacting nuclei lie in the low end (<130 pc) of this relation, while only 30% of the advanced mergers do so, suggesting that in the early interaction phases the activity occurs in more compact and obscured regions. About two thirds of the nuclei are above the Eddington limit which is consistent with the detection of massive outflows in local ULIRGs and the potential role of radiation pressure in the launching process., Comment: Accepted for publication in A&A
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- 2021
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215. Pylot: A Modular Platform for Exploring Latency-Accuracy Tradeoffs in Autonomous Vehicles
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Gog, Ionel, Kalra, Sukrit, Schafhalter, Peter, Wright, Matthew A., Gonzalez, Joseph E., and Stoica, Ion
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Computer Science - Robotics - Abstract
We present Pylot, a platform for autonomous vehicle (AV) research and development, built with the goal to allow researchers to study the effects of the latency and accuracy of their models and algorithms on the end-to-end driving behavior of an AV. This is achieved through a modular structure enabled by our high-performance dataflow system that represents AV software pipeline components (object detectors, motion planners, etc.) as a dataflow graph of operators which communicate on data streams using timestamped messages. Pylot readily interfaces with popular AV simulators like CARLA, and is easily deployable to real-world vehicles with minimal code changes. To reduce the burden of developing an entire pipeline for evaluating a single component, Pylot provides several state-of-the-art reference implementations for the various components of an AV pipeline. Using these reference implementations, a Pylot-based AV pipeline is able to drive a real vehicle, and attains a high score on the CARLA Autonomous Driving Challenge. We also present several case studies enabled by Pylot, including evidence of a need for context-dependent components, and per-component time allocation. Pylot is open source, with the code available at https://github.com/erdos-project/pylot., Comment: ICRA 2021; 8 pages, 4 figures, 1 table
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- 2021
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216. HADES RV Programme with HARPS-N at TNG XIII. A sub-Neptune around the M dwarf GJ 720 A
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González-Álvarez, E., Petralia, A., Micela, G., Maldonado, J., Affer, L., Maggio, A., Covino, E., Damasso, M., Lanza, A. F., Perger, M., Pinamonti, M., Poretti, E., Scandariato, G., Sozzetti, A., Bignamini, A., Giacobbe, P., Leto, G., Pagano, I., Sánchez, R. Zanmar, Hernández, J. I. González, Rebolo, R., Ribas, I., Mascareño, A. Suárez, and Toledo-Padrón, B.
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Astrophysics - Earth and Planetary Astrophysics - Abstract
Context. The high number of super-Earth and Earth-like planets in the habitable zone (HZ) detected around M-dwarf stars in the last years has revealed these stellar objects to be the key for planetary radial velocity (RV) searches. Aims. Using the HARPS-N spectrograph within The HArps-n red Dwarf Exoplanet Survey (HADES) we reach the precision needed to detect small planets with a few Earth masses using the RV technique. Methods. We obtained 138 HARPS-N RV measurements between 2013 May and 2020 September of GJ 720 A, classified as an M0.5V star located at a distance of 15.56 pc. To characterize the stellar variability and to discern the periodic variation due to the Keplerian signals from those related to stellar activity, the HARPS-N spectroscopic activity indicators and the simultaneous photometric observations were analyzed. The combined analysis of HARPS-N RVs and activity indicators let us to address the nature of the periodic signals. The final model and the orbital planetary parameters were obtained by fitting simultaneously the stellar variability and the Keplerian signal using a Gaussian process regression and following a Bayesian criterion. Results. The HARPS-N RV periodic signals around 40 d and 100 d have counterparts at the same frequencies in HARPS-N activity indicators and photometric light curves. Then we attribute these periodicities to stellar activity the former period being likely associated with the stellar rotation. GJ 720 A shows the most significant signal at 19.466$\pm$0.005 d with no counterparts in any stellar activity indices. We hence ascribe this RV signal, having a semiamplitude of 4.72$\pm$0.27 m/s , to the presence of a sub-Neptune mass planet. The planet GJ 720 Ab has a minimum mass of 13.64$\pm$0.79 M$_{\oplus}$, it is in circular orbit at 0.119$\pm$0.002 AU from its parent star, and lies inside the inner boundary of the HZ around its parent star.
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- 2021
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217. Enhancing the Interactivity of Dataframe Queries by Leveraging Think Time
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Xin, Doris, Petersohn, Devin, Tang, Dixin, Wu, Yifan, Gonzalez, Joseph E., Hellerstein, Joseph M., Joseph, Anthony D., and Parameswaran, Aditya G.
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Computer Science - Databases - Abstract
We propose opportunistic evaluation, a framework for accelerating interactions with dataframes. Interactive latency is critical for iterative, human-in-the-loop dataframe workloads for supporting exploratory data analysis. Opportunistic evaluation significantly reduces interactive latency by 1) prioritizing computation directly relevant to the interactions and 2) leveraging think time for asynchronous background computation for non-critical operators that might be relevant to future interactions. We show, through empirical analysis, that current user behavior presents ample opportunities for optimization, and the solutions we propose effectively harness such opportunities.
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- 2021
218. An ultra-short-period transiting super-Earth orbiting the M3 dwarf TOI-1685
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Bluhm, P., Palle, E., Molaverdikhani, K., Kemmer, J., Hatzes, A. P., Kossakowski, D., Stock, S., Caballero, J. A., Lillo-Box, J., Bejar, V. J. S ., Soto, M. G., Amado, P. J., Brown, P., Cadieux, C., Cloutier, R., Collins, K. A., Collins, K. I., Cortes-Contreras, M., Doyon, R., Dreizler, S., Espinoza, N., Fukui, A., Gonzalez-Alvarez, E., Henning, Th., Horne, K., Jeffers, S. V., Jenkins, J. M., Jensen, E. L. N., Kaminski, A., Kielkopf, J. F., Kusakabe, N., Kuerster, M., Lafreniere, D., Luque, R., Murgas, F., Montes, D., Morales, J. C., Narita, N., Passegger, V. M., Quirrenbach, A., Schoefer, P., Reffert, S., Reiners, A., Ribas, I., Ricker, G. R., Seager, S., Schweitzer, A., Schwarz, R. P., Tamura, M., Trifonov, T., Vanderspek, R., Winn, J., Zechmeister, M., and Osorio, M. R. Zapatero
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Astrophysics - Earth and Planetary Astrophysics - Abstract
Dynamical histories of planetary systems, as well as atmospheric evolution of highly irradiated planets, can be studied by characterizing the ultra-short-period planet population, which the TESS mission is particularly well suited to discover. Here, we report on the follow-up of a transit signal detected in the TESS sector 19 photometric time series of the M3.0 V star TOI-1685 (2MASS J04342248+4302148). We confirm the planetary nature of the transit signal, which has a period of P_b=0.6691403+0.0000023-0.0000021 d, using precise radial velocity measurements taken with the CARMENES spectrograph. From the joint photometry and radial velocity analysis, we estimate the following parameters for TOI-1685 b: a mass of M_b=3.78+/-0.63 M_Earth, a radius of R_b=1.70+/-0.07 R_Earth, which together result in a bulk density of rho_b=4.21+0.95-0.82 g/cm3, and an equilibrium temperature of Teq_b=1069+/-16 K. TOI-1685 b is the least dense ultra-short period planet around an M dwarf known to date. TOI-1685 b is also one of the hottest transiting Earth-size planets with accurate dynamical mass measurements, which makes it a particularly attractive target for thermal emission spectroscopy. Additionally, we report a further non-transiting planet candidate in the system, TOI-1685[c], with an orbital period of P_[c]=9.02+0.10-0.12 d., Comment: 18 pages, 15 figures
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- 2021
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219. CON-quest: Searching for the most obscured galaxy nuclei
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Falstad, N., Aalto, S., König, S., Onishi, K., Muller, S., Gorski, M., Sato, M., Stanley, F., Combes, F., González-Alfonso, E., Mangum, J. G., Evans, A. S., Barcos-Muñoz, L., Privon, G. C., Linden, S. T., Díaz-Santos, T., Martín, S., Sakamoto, K., Harada, N., Fuller, G. A., Gallagher, J. S., van der Werf, P. P., Viti, S., Greve, T. R., García-Burillo, S., Henkel, C., Imanishi, M., Izumi, T., Nishimura, Y., Ricci, C., and Mühle, S.
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Astrophysics - Astrophysics of Galaxies - Abstract
Some luminous and ultraluminous infrared galaxies (LIRGs and ULIRGs) host extremely compact and dusty nuclei. The intense infrared radiation arising from warm dust in these sources is prone to excite vibrational levels of molecules such as HCN. This results in emission from the rotational transitions of vibrationally excited HCN (HCN-vib), with the brightest emission found in compact obscured nuclei (CONs). We aim to establish how common CONs are in the local Universe, and whether their prevalence depends on the luminosity or other properties of the host galaxy. We have conducted an Atacama Large Millimeter/submillimeter Array (ALMA) survey of the rotational J=3-2 transition of HCN-vib in a sample of 46 far-infrared luminous galaxies. Compact obscured nuclei are identified in 38 percent of ULIRGs, 21 percent of LIRGs, and 0 percent of lower luminosity galaxies. We find no dependence on the inclination of the host galaxy, but strong evidence of lower IRAS 25 to 60 {\mu}m flux density ratios (f25/f60) in CONs compared to the rest of the sample. Furthermore, we find that CONs have stronger silicate features (s9.7{\mu}m) but similar PAH equivalent widths (EQW6.2{\mu}m) compared to other galaxies. In the local Universe, CONs are primarily found in (U)LIRGs. High resolution continuum observations of the individual nuclei are required to determine if the CON phenomenon is related to the inclinations of the nuclear disks. The lower f25/f60 ratios in CONs as well as the results for the mid-infrared diagnostics investigated are consistent with large dust columns shifting the nuclear radiation to longer wavelengths, making the mid- and far-infrared "photospheres" significantly cooler than the interior regions. To assess the importance of CONs in the context of galaxy evolution, it is necessary to extend this study to higher redshifts where (U)LIRGs are more common., Comment: 16 pages, 11 figures, Accepted for publication in Astronomy and Astrophysics
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- 2021
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220. A super-Earth on a close-in orbit around the M1V star GJ 740. A HADES and CARMENES collaboration
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Toledo-Padrón, B., Mascareño, A. Suárez, Hernández, J. I. González, Rebolo, R., Pinamonti, M., Perger, M., Scandariato, G., Damasso, M., Sozzetti, A., Maldonado, J., Desidera, S., Ribas, I., Micela, G., Affer, L., González-Alvarez, E., Leto, G., Pagano, I., Sánchez, R. Zanmar, Giacobbe, P., Herrero, E., Morales, J. C., Amado, P. J., Caballero, J. A., Quirrenbach, A., Reiners, A., and Zechmeister, M.
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Astrophysics - Earth and Planetary Astrophysics ,Astrophysics - Solar and Stellar Astrophysics - Abstract
M-dwarfs have proven to be ideal targets for planetary radial velocity (RV) searches due to their higher planet-star mass contrast. The HADES and CARMENES programs aim to carry out extensive searches of exoplanetary systems around this type of stars in the northern hemisphere, allowing us to address statistically the properties of the planets orbiting these objects. In this work, we perform a spectroscopic and photometric study of one of the program stars (GJ 740), which exhibits a short-period RV signal compatible with a planetary companion. We carried out a spectroscopic analysis based on 129 HARPS-N spectra taken over a time-span of 6 yr combined with 57 HARPS spectra taken over 4 yr, as well as 32 CARMENES spectra taken during more than 1 yr, resulting in a dataset with a time coverage of 10 yr. We also relied on 459 measurements from the public ASAS survey with a time-coverage of 8 yr along with 5 yr of photometric magnitudes from the EXORAP project taken in the $V$, $B$, $R$, and $I$ filters to carry out a photometric study. Both analyses were made using Markov Chain Monte Carlo (MCMC) simulations and Gaussian Process regression to model the activity of the star. We present the discovery of a short-period super-Earth with an orbital period of 2.37756$^{+0.00013}_{-0.00011}$ d and a minimum mass of 2.96$^{+0.50}_{-0.48}$ M$_{\oplus}$. We offer an update to the previously reported characterization of the magnetic cycle and rotation period of the star, obtaining values of $P_{\rm rot}$=35.563$\pm$0.071 d and $P_{\rm cycle}$=2800$\pm$150 d. Furthermore, the RV time-series exhibits a possibly periodic long-term signal which might be related to a Saturn-mass planet of $\sim$ 100 M$_{\oplus}$., Comment: 18 pages, 12 figures
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- 2021
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221. Point-of-Care Ultrasonography to Confirm Endotracheal Tube Placement: A Review for the Emergency Nurse Practitioner
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Gonzalez, Juan M., Ortega, Johis, Gonzalez, Juan E., Crenshaw, Nichole, McGhee, Stephen, and Groom, Jeffrey
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- 2024
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222. Cardiovascular Outcomes in GRADE (Glycemia Reduction Approaches in Type 2 Diabetes: A Comparative Effectiveness Study)
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Green, Jennifer B., Everett, Brendan M., Ghosh, Alokananda, Younes, Naji, Krause-Steinrauf, Heidi, Barzilay, Joshua, Desouza, Cyrus, Inzucchi, Silvio E., Pokharel, Yashashwi, Schade, David, Scrymgeour, Alexandra, Tan, Meng H., Utzschneider, Kristina M., Mudaliar, Sunder, Crandall, J.P., McKee, M.D., Behringer-Massera, S., Brown-Friday, J., Xhori, E., Ballentine-Cargill, K., Duran, S., Estrella, H., Gonzalez de la Torre, S., Lukin, J., Phillips, L.S., Burgess, E., Olson, D., Rhee, M., Wilson, P., Raines, T.S., Boers, J., Costello, J., Maher-Albertelli, M., Mungara, R., Savoye, L., White, C.A., Gullett, C., Holloway, L., Morehead, F., Person, S., Sibymon, M., Tanukonda, S., Adams, C., Ross, A., Balasubramanyam, A., Gaba, R., Gonzalez Hattery, E., Ideozu, A., Jimenez, J., Montes, G., Wright, C., Hollander, P., Roe, E., Jackson, A., Smiley, A., Burt, P., Estrada, L., Chionh, K., Ismail-Beigi, F., Falck-Ytter, C., Sayyed Kassem, L., Sood, A., Tiktin, M., Kulow, T., Newman, C., Stancil, K.A., Cramer, B., Iacoboni, J., Kononets, M.V., Sanders, C., Tucker, L., Werner, A., Maxwell, A., McPhee, G., Patel, C., Colosimo, L., Krol, A., Goland, R., Pring, J., Alfano, L., Kringas, P., Hausheer, C., Tejada, J., Gumpel, K., Kirpitch, A., Schneier, H., AbouAssi, H., Chatterjee, R., Feinglos, M.N., English Jones, J., Khan, S.A., Kimpel, J.B., Zimmer, R.P., Furst, M., Satterwhite, B.M., Thacker, C.R., Evans Kreider, K., Mariash, C.N., Mather, K.J., Ismail, H.M., Lteif, A., Mullen, M., Hamilton, T., Patel, N., Riera, G., Jackson, M., Pirics, V., Aguillar, D., Howard, D., Hurt, S., Bergenstal, R., Carlson, A., Martens, T., Johnson, M., Hill, R., Hyatt, J., Jensen, C., Madden, M., Martin, D., Willis, H., Konerza, W., Yang, S., Kleeberger, K., Passi, R., Fortmann, S., Herson, M., Mularski, K., Glauber, H., Prihoda, J., Ash, B., Carlson, C., Ramey, P.A., Schield, E., Torgrimson-Ojerio, B., Arnold, K., Kauffman, B., Panos, E., Sahnow, S., Bays, K., Berame, K., Cook, J., Ghioni, D., Gluth, J., Schell, K., Criscola, J., Friason, C., Jones, S., Nazarov, S., Rassouli, N., Puttnam, R., Ojoawo, B., Nelson, R., Curtis, M., Hollis, B., Sanders-Jones, C., Stokes, K., El-Haqq, Z., Kolli, A., Tran, T., Wexler, D., Larkin, M.E., Meigs, J., Chambers, B., Dushkin, A., Rocchio, G., Yepes, M., Steiner, B., Dulin, H., Cayford, M., Chu, K., DeManbey, A., Hillard, M., Martin, K., Thangthaeng, N., Gurry, L., Kochis, R., Raymond, E., Ripley, V., Stevens, C., Park, J., Aroda, V., Ghazi, A., Magee, M., Ressing, A., Loveland, A., Hamm, M., Hurtado, M., Kuhn, A., Leger, J., Manandhar, L., Mwicigi, F., Sanchez, O., Young, T., Garg, R., Lagari-Libhaber, V., Florez, H.J., Valencia, W.M., Marks, J., Casula, S., Oropesa-Gonzalez, L., Hue, L., Cuadot, A., Nieto-Martinez, R., Riccio Veliz, A.K., Gutt, M., Kendal, Y.J., Veciana, B., Ahmann, A., Aby-Daniel, D., Joarder, F., Morimoto, V., Sprague, C., Yamashita, D., Cady, N., Rivera-Eschright, N., Kirchhoff, P., Morales Gomez, B., Adducci, J., Goncharova, A., Hox, S.H., Petrovitch, H., Matwichyna, M., Jenkins, V., Broadwater, L., Ishii, R.R., Bermudez, N.O., Hsia, D.S., Cefalu, W.T., Greenway, F.L., Waguespack, C., King, E., Fry, G., Dragg, A., Gildersleeve, B., Arceneaux, J., Haynes, N., Thomassie, A., Pavlionis, M., Bourgeois, B., Hazlett, C., Henry, R., Boeder, S., Pettus, J., Diaz, E., Garcia-Acosta, D., Maggs, S., DeLue, C., Stallings, A., Castro, E., Hernandez, S., Krakoff, J., Curtis, J.M., Killean, T., Khalid, M., Joshevama, E., Diaz, E., Martin, D., Tsingine, K., Karshner, T., Albu, J., Pi-Sunyer, F.X., Frances, S., Maggio, C., Ellis, E., Bastawrose, J., Gong, X., Banerji, M.A., August, P., Lee, M., Lorber, D., Brown, N.M., Josephson, D.H., Thomas, L.L., Tsovian, M., Cherian, A., Jacobson, M.H., Mishko, M.M., Kirkman, M.S., Buse, J.B., Diner, J., Dostou, J., Machineni, S., Young, L., Bergamo, K., Goley, A., Kerr, J., Largay, J.F., Guarda, S., Cuffee, J., Culmer, D., Fraser, R., Almeida, H., Coffer, S., Debnam, E., Kiker, L., Morton, S., Josey, K., Fuller, G., Garvey, W.T., Cherrington, A.L., Dyer, D., Lawson, M.C.R., Griffith, O., Agne, A., McCullars, S., Cohen, R.M., Craig, J., Rogge, M.C., Burton, K., Kersey, K., Wilson, C., Lipp, S., Vonder Meulen, M.B., Adkins, C., Onadeko, T., Rasouli, N., Baker, C., Schroeder, E., Razzaghi, M., Lyon, C., Penaloza, R., Underkofler, C., Lorch, R., Douglass, S., Steiner, S., Sivitz, W.I., Cline, E., Knosp, L.K., McConnell, J., Lowe, T., Herman, W.H., Pop-Busui, R., Martin, C., Waltje, A., Katona, A., Goodhall, L., Eggleston, R., Kuo, S., Bojescu, S., Bule, S., Kessler, N., LaSalle, E., Whitley, K., Seaquist, E.R., Bantle, A., Harindhanavudhi, T., Kumar, A., Redmon, B., Bantle, J., Coe, M., Mech, M., Taddese, A., Lesne, L., Smith, S., Kuechenmeister, L., Shivaswamy, V., Burbach, S., Rodriguez, M.G., Seipel, K., Alfred, A., Morales, A.L., Eggert, J., Lord, G., Taylor, W., Tillson, R., Adolphe, A., Burge, M., Duran-Valdez, E., Martinez, J., Bancroft, A., Kunkel, S., Ali Jamaleddin Ahmad, F., Hernandez McGinnis, D., Pucchetti, B., Scripsick, E., Zamorano, A., DeFronzo, R.A., Cersosimo, E., Abdul-Ghani, M., Triplitt, C., Juarez, D., Mullen, M., Garza, R.I., Verastiqui, H., Wright, K., Puckett, C., Raskin, P., Rhee, C., Abraham, S., Jordan, L.F., Sao, S., Morton, L., Smith, O., Osornio Walker, L., Schnurr-Breen, L., Ayala, R., Kreymer, R.B., Sturgess, D., Kahn, S.E., Alarcon-Casas Wright, L., Boyko, E.J., Tsai, E.C., Trence, D.L., Trikudanathan, S., Fattaleh, B.N., Montgomery, B.K., Atkinson, K.M., Kozedub, A., Concepcion, T., Moak, C., Prikhodko, N., Rhothisen, S., Elasy, T.A., Martin, S., Shackelford, L., Goidel, R., Hinkle, N., Lovell, C., Myers, J., Lipps Hogan, J., McGill, J.B., Salam, M., Schweiger, T., Kissel, S., Recklein, C., Clifton, M.J., Tamborlane, W., Camp, A., Gulanski, B., Pham, K., Alguard, M., Gatcomb, P., Lessard, K., Perez, M., Iannone, L., Magenheimer, E., Montosa, A., Cefalu, W.T., Fradkin, J., Burch, H.B., Bremer, A.A., Nathan, D.M., Lachin, J.M., Buse, J.B., Kahn, S.E., Larkin, M.E., Tiktin, M., Wexler, D., Burch, H.B., Bremer, A.A., Lachin, J.M., Bebu, I., Butera, N., Buys, C.J., Fagan, A., Gao, Y., Gramzinski, M.R., Hall, S.D., Kazemi, E., Legowski, E., Liu, H., Suratt, C., Tripputi, M., Arey, A., Backman, M., Bethepu, J., Lund, C., Mangat Dhaliwal, P., McGee, P., Mesimer, E., Ngo, L., Steffes, M., Seegmiller, J., Saenger, A., Arends, V., Gabrielson, D., Conner, T., Warren, S., Day, J., Huminik, J., Soliman, E.Z., Zhang, Z.M., Campbell, C., Hu, J., Keasler, L., Hensley, S., Li, Y., Herman, W.H., Kuo, S., Martin, C., Waltje, A., Mihalcea, R., Min, D.J., Perez-Rosas, V., Prosser, L., Resnicow, K., Ye, W., Shao, H., Zhang, P., Luchsinger, J., Sanchez, D., Assuras, S., Groessl, E., Sakha, F., Chong, H., Hillery, N., Abdouch, I., Bahtiyar, G., Brantley, P., Broyles, F.E., Canaris, G., Copeland, P., Craine, J.J., Fein, W.L., Gliwa, A., Hope, L., Lee, M.S., Meiners, R., Meiners, V., O’Neal, H., Park, J.E., Sacerdote, A., Sledge Jr, E., Soni, L., Steppel-Reznik, J., and Turchin, A.
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- 2024
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223. Imaging neutron capture cross sections: i-TED proof-of-concept and future prospects based on Machine-Learning techniques
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Babiano-Suárez, V., Lerendegui-Marco, J., Balibrea-Correa, J., Caballero, L., Calvo, D., Ladarescu, I., Domingo-Pardo, C., Calviño, F., Casanovas, A., Tarifeño-Saldivia, A., Alcayne, V., Guerrero, C., Millán-Callado, M. A., González, M. T. Rodríguez, Barbagallo, M., Aberle, O., Amaducci, S., Andrzejewski, J., Audouin, L., Bacak, M., Bennett, S., Berthoumieux, E., Billowes, J., Bosnar, D., Brown, A., Busso, M., Caamaño, M., Calviani, M., Cano-Ott, D., Cerutti, F., Chiaveri, E., Colonna, N., Cortés, G., Cortés-Giraldo, M. A., Cosentino, L., Cristallo, S., Damone, L. A., Davies, P. J., Diakaki, M., Dietz, M., Dressler, R., Ducasse, Q., Dupont, E., Durán, I., Eleme, Z., Fern\', B., ez-Domínguez, Ferrari, A., Finocchiaro, P., Furman, V., Göbel, K., Garg, R., Gawlik, A., Gilardoni, S., Gonçalves, I. F., González-Romero, E., Gunsing, F., Harada, H., Heinitz, S., Heyse, J., Jenkins, D. G., Junghans, A., Käppeler, F., Kadi, Y., Kimura, A., Knapova, I., Kokkoris, M., Kopatch, Y., Krtička, M., Kurtulgil, D., Lederer-Woods, C., Leeb, H., Lonsdale, S. J., Macina, D., Manna, A., Martinez, T., Masi, A., Massimi, C., Mastinu, P., Mastromarco, M., Maugeri, E. A., Mazzone, A., Mendoza, E., Mengoni, A., Michalopoulou, V., Milazzo, P. M., Mingrone, F., Moreno-Soto, J., Musumarra, A., Negret, A., Ogállar, F., Oprea, A., Patronis, N., Pavlik, A., Perkowski, J., Persanti, L., Petrone, C., Pirovano, E., Porras, I., Praena, J., Quesada, J. M., Ramos-Doval, D., Rauscher, T., Reifarth, R., Rochman, D., Rubbia, C., Sabaté-Gilarte, M., Saxena, A., Schillebeeckx, P., Schumann, D., Sekhar, A., Smith, A. G., Sosnin, N. V., Sprung, P., Stamatopoulos, A., Tagliente, G., Tain, J. L., Tassan-Got, L., Thomas, Th., Torres-Sánchez, P., Tsinganis, A., Ulrich, J., Urlass, S., Valenta, S., Vannini, G., Variale, V., Vaz, P., Ventura, A., Vescovi, D., Vlachoudis, V., Vlastou, R., Wallner, A., Woods, P. J., Wright, T., and Žugec, P.
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Physics - Instrumentation and Detectors ,Astrophysics - Instrumentation and Methods for Astrophysics ,Nuclear Experiment - Abstract
i-TED is an innovative detection system which exploits Compton imaging techniques to achieve a superior signal-to-background ratio in ($n,\gamma$) cross-section measurements using time-of-flight technique. This work presents the first experimental validation of the i-TED apparatus for high-resolution time-of-flight experiments and demonstrates for the first time the concept proposed for background rejection. To this aim both $^{197}$Au($n,\gamma$) and $^{56}$Fe($n, \gamma$) reactions were measured at CERN n\_TOF using an i-TED demonstrator based on only three position-sensitive detectors. Two \cds detectors were also used to benchmark the performance of i-TED. The i-TED prototype built for this study shows a factor of $\sim$3 higher detection sensitivity than state-of-the-art \cds detectors in the $\sim$10~keV neutron energy range of astrophysical interest. This paper explores also the perspectives of further enhancement in performance attainable with the final i-TED array consisting of twenty position-sensitive detectors and new analysis methodologies based on Machine-Learning techniques., Comment: 16 pages, 16 figures
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- 2020
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224. Online Learning Demands in Max-min Fairness
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Kandasamy, Kirthevasan, Sela, Gur-Eyal, Gonzalez, Joseph E, Jordan, Michael I, and Stoica, Ion
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Statistics - Machine Learning ,Computer Science - Artificial Intelligence ,Computer Science - Machine Learning - Abstract
We describe mechanisms for the allocation of a scarce resource among multiple users in a way that is efficient, fair, and strategy-proof, but when users do not know their resource requirements. The mechanism is repeated for multiple rounds and a user's requirements can change on each round. At the end of each round, users provide feedback about the allocation they received, enabling the mechanism to learn user preferences over time. Such situations are common in the shared usage of a compute cluster among many users in an organisation, where all teams may not precisely know the amount of resources needed to execute their jobs. By understating their requirements, users will receive less than they need and consequently not achieve their goals. By overstating them, they may siphon away precious resources that could be useful to others in the organisation. We formalise this task of online learning in fair division via notions of efficiency, fairness, and strategy-proofness applicable to this setting, and study this problem under three types of feedback: when the users' observations are deterministic, when they are stochastic and follow a parametric model, and when they are stochastic and nonparametric. We derive mechanisms inspired by the classical max-min fairness procedure that achieve these requisites, and quantify the extent to which they are achieved via asymptotic rates. We corroborate these insights with an experimental evaluation on synthetic problems and a web-serving task.
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- 2020
225. BeBold: Exploration Beyond the Boundary of Explored Regions
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Zhang, Tianjun, Xu, Huazhe, Wang, Xiaolong, Wu, Yi, Keutzer, Kurt, Gonzalez, Joseph E., and Tian, Yuandong
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Computer Science - Machine Learning ,Computer Science - Artificial Intelligence ,Statistics - Machine Learning - Abstract
Efficient exploration under sparse rewards remains a key challenge in deep reinforcement learning. To guide exploration, previous work makes extensive use of intrinsic reward (IR). There are many heuristics for IR, including visitation counts, curiosity, and state-difference. In this paper, we analyze the pros and cons of each method and propose the regulated difference of inverse visitation counts as a simple but effective criterion for IR. The criterion helps the agent explore Beyond the Boundary of explored regions and mitigates common issues in count-based methods, such as short-sightedness and detachment. The resulting method, BeBold, solves the 12 most challenging procedurally-generated tasks in MiniGrid with just 120M environment steps, without any curriculum learning. In comparison, the previous SoTA only solves 50% of the tasks. BeBold also achieves SoTA on multiple tasks in NetHack, a popular rogue-like game that contains more challenging procedurally-generated environments.
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- 2020
226. RLlib Flow: Distributed Reinforcement Learning is a Dataflow Problem
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Liang, Eric, Wu, Zhanghao, Luo, Michael, Mika, Sven, Gonzalez, Joseph E., and Stoica, Ion
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Computer Science - Machine Learning ,Computer Science - Distributed, Parallel, and Cluster Computing ,I.2.11 ,I.2.6 ,C.4 - Abstract
Researchers and practitioners in the field of reinforcement learning (RL) frequently leverage parallel computation, which has led to a plethora of new algorithms and systems in the last few years. In this paper, we re-examine the challenges posed by distributed RL and try to view it through the lens of an old idea: distributed dataflow. We show that viewing RL as a dataflow problem leads to highly composable and performant implementations. We propose RLlib Flow, a hybrid actor-dataflow programming model for distributed RL, and validate its practicality by porting the full suite of algorithms in RLlib, a widely adopted distributed RL library. Concretely, RLlib Flow provides 2-9 code savings in real production code and enables the composition of multi-agent algorithms not possible by end users before. The open-source code is available as part of RLlib at https://github.com/ray-project/ray/tree/master/rllib., Comment: NeurIPS 2021. The first two authors contributed equally to this work
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- 2020
227. A model-independent reconstruction of dark sector interactions
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von Marttens, Rodrigo, Gonzalez, Javier E., Alcaniz, Jailson, Marra, Valerio, and Casarini, Luciano
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Astrophysics - Cosmology and Nongalactic Astrophysics - Abstract
Relaxing the conventional assumption of a minimal coupling between the dark matter (DM) and dark energy (DE) fields introduces significant changes in the predicted evolution of the Universe. Therefore, testing such a possibility constitutes an essential task not only for cosmology but also for fundamental physics. In a previous communication [Phys. Rev. D99, 043521, 2019], we proposed a new null test for the $\Lambda$CDM model based on the time dependence of the ratio between the DM and DE energy densities which is also able to detect potential signatures of interaction between the dark components. In this work, we extend that analysis avoiding the $ \Lambda$CDM assumption and reconstruct the interaction in the dark sector in a fully model-independent way using data from type Ia supernovae, cosmic chronometers and baryonic acoustic oscillations. According to our analysis, the $\Lambda$CDM model is consistent with our model-independent approach at least at $3\sigma$ CL over the entire range of redshift studied. On the other hand, our analysis shows that the current background data do not allow us to rule out the existence of an interaction in the dark sector. Finally, we present a forecast for next-generation LSS surveys. In particular, we show that Euclid and SKA will be able to distinguish interacting models with about 4\% of precision at $z\approx 1$., Comment: 12 pages, 7 figures. Accepted for publication in Physical Review D
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- 2020
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228. Intermittent Visual Servoing: Efficiently Learning Policies Robust to Instrument Changes for High-precision Surgical Manipulation
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Paradis, Samuel, Hwang, Minho, Thananjeyan, Brijen, Ichnowski, Jeffrey, Seita, Daniel, Fer, Danyal, Low, Thomas, Gonzalez, Joseph E., and Goldberg, Ken
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Computer Science - Robotics - Abstract
Automation of surgical tasks using cable-driven robots is challenging due to backlash, hysteresis, and cable tension, and these issues are exacerbated as surgical instruments must often be changed during an operation. In this work, we propose a framework for automation of high-precision surgical tasks by learning sample efficient, accurate, closed-loop policies that operate directly on visual feedback instead of robot encoder estimates. This framework, which we call intermittent visual servoing (IVS), intermittently switches to a learned visual servo policy for high-precision segments of repetitive surgical tasks while relying on a coarse open-loop policy for the segments where precision is not necessary. To compensate for cable-related effects, we apply imitation learning to rapidly train a policy that maps images of the workspace and instrument from a top-down RGB camera to small corrective motions. We train the policy using only 180 human demonstrations that are roughly 2 seconds each. Results on a da Vinci Research Kit suggest that combining the coarse policy with half a second of corrections from the learned policy during each high-precision segment improves the success rate on the Fundamentals of Laparoscopic Surgery peg transfer task from 72.9% to 99.2%, 31.3% to 99.2%, and 47.2% to 100.0% for 3 instruments with differing cable-related effects. In the contexts we studied, IVS attains the highest published success rates for automated surgical peg transfer and is significantly more reliable than previous techniques when instruments are changed. Supplementary material is available at https://tinyurl.com/ivs-icra., Comment: 6 pages, 5 figures, 4 tables, submitted to ICRA 2021, supplementary material at https://tinyurl.com/ivs-icra
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- 2020
229. Untangling Dense Knots by Learning Task-Relevant Keypoints
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Grannen, Jennifer, Sundaresan, Priya, Thananjeyan, Brijen, Ichnowski, Jeffrey, Balakrishna, Ashwin, Hwang, Minho, Viswanath, Vainavi, Laskey, Michael, Gonzalez, Joseph E., and Goldberg, Ken
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Computer Science - Robotics ,Computer Science - Artificial Intelligence ,Computer Science - Machine Learning - Abstract
Untangling ropes, wires, and cables is a challenging task for robots due to the high-dimensional configuration space, visual homogeneity, self-occlusions, and complex dynamics. We consider dense (tight) knots that lack space between self-intersections and present an iterative approach that uses learned geometric structure in configurations. We instantiate this into an algorithm, HULK: Hierarchical Untangling from Learned Keypoints, which combines learning-based perception with a geometric planner into a policy that guides a bilateral robot to untangle knots. To evaluate the policy, we perform experiments both in a novel simulation environment modelling cables with varied knot types and textures and in a physical system using the da Vinci surgical robot. We find that HULK is able to untangle cables with dense figure-eight and overhand knots and generalize to varied textures and appearances. We compare two variants of HULK to three baselines and observe that HULK achieves 43.3% higher success rates on a physical system compared to the next best baseline. HULK successfully untangles a cable from a dense initial configuration containing up to two overhand and figure-eight knots in 97.9% of 378 simulation experiments with an average of 12.1 actions per trial. In physical experiments, HULK achieves 61.7% untangling success, averaging 8.48 actions per trial. Supplementary material, code, and videos can be found at https://tinyurl.com/y3a88ycu., Comment: Conference on Robot Learning (CoRL) 2020 Oral. First two authors contributed equally
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- 2020
230. Geodesic Logistic Analysis of Lumbar Spine Intervertebral Disc Shapes in Supine and Standing Positions
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Han, Ye, Fishbaugh, James, Gonzalez, Christian E., Aboyotes, Donald A., Vicory, Jared, Tang, Simon Y., Paniagua, Beatriz, Goos, Gerhard, Founding Editor, Hartmanis, Juris, Founding Editor, Bertino, Elisa, Editorial Board Member, Gao, Wen, Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Yung, Moti, Editorial Board Member, Wachinger, Christian, editor, Paniagua, Beatriz, editor, Elhabian, Shireen, editor, Li, Jianning, editor, and Egger, Jan, editor
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- 2023
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231. Do Emotions Matter? Reviewing the Last Generation of Studies on Climate Change Communication and Tourist Behaviour
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Lam-González, Yen E., León, Carmelo J., de León, Javier, Ebnou, Mohamed Abderrahmane, Kacprzyk, Janusz, Series Editor, Gomide, Fernando, Advisory Editor, Kaynak, Okyay, Advisory Editor, Liu, Derong, Advisory Editor, Pedrycz, Witold, Advisory Editor, Polycarpou, Marios M., Advisory Editor, Rudas, Imre J., Advisory Editor, Wang, Jun, Advisory Editor, Castillo Ossa, Luis Fernando, editor, Isaza, Gustavo, editor, Cardona, Óscar, editor, Castrillón, Omar Danilo, editor, Corchado Rodriguez, Juan Manuel, editor, and De la Prieta Pintado, Fernando, editor
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- 2023
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232. Magma Storage and Migration in El Hierro During the Period 2011–2014
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Domínguez Cerdeña, I., Charco, M., González-Alonso, E., del Fresno, C., Benito-Saz, M. A., García-Cañada, L., Cimarelli, Corrado, Series Editor, Mueller, Sebastian, Series Editor, and González, Pablo J., editor
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- 2023
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233. Review on Nuclear Thermal Propulsion Analysis of Fuel Element and Simulation Methods
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Cárdenas R., César A., Collazos Morales, Carlos Andrés, Amaya, Juan Carlos, Castro, Fabian C., Mora, César E., Gonzalez, Ramón E. R., Simancas-García, José L., Pertuz, Farid A. Meléndez, Goos, Gerhard, Founding Editor, Hartmanis, Juris, Founding Editor, Bertino, Elisa, Editorial Board Member, Gao, Wen, Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Yung, Moti, Editorial Board Member, Gervasi, Osvaldo, editor, Murgante, Beniamino, editor, Taniar, David, editor, Apduhan, Bernady O., editor, Braga, Ana Cristina, editor, Garau, Chiara, editor, and Stratigea, Anastasia, editor
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- 2023
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234. Optimizing Nutrition for Exercise Exercise and Sports
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Gonzalez, Drew E., Latt, Scarlett Lin, Blalock, Tricia, Leutholtz, Brian, Kreider, Richard B., Bendich, Adrianne, Series Editor, Bales, Connie W., Series Editor, Temple, Norman J., editor, Wilson, Ted, editor, Jacobs, Jr., David R., editor, and Bray, George A., editor
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- 2023
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235. Speaker Identification in Noisy Environments for Forensic Purposes
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Rodarte-Rodríguez, Armando, Becerra-Sánchez, Aldonso, De La Rosa-Vargas, José I., Escalante-García, Nivia I., Olvera-González, José E., de J. Velásquez-Martínez, Emmanuel, Zepeda-Valles, Gustavo, Kacprzyk, Janusz, Series Editor, Gomide, Fernando, Advisory Editor, Kaynak, Okyay, Advisory Editor, Liu, Derong, Advisory Editor, Pedrycz, Witold, Advisory Editor, Polycarpou, Marios M., Advisory Editor, Rudas, Imre J., Advisory Editor, Wang, Jun, Advisory Editor, Mejia, Jezreel, editor, Muñoz, Mirna, editor, Rocha, Álvaro, editor, and Hernández-Nava, Víctor, editor
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- 2023
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236. Safety and Efficacy of VP-102 (Cantharidin, 0.7% w/v) in Molluscum Contagiosum by Body Region: Post hoc Pooled Analyses from Two Phase III Randomized Trials.
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Eichenfield, Lawrence F, Kwong, Pearl, Gonzalez, Mercedes E, Yan, Albert, D'Arnaud, Pieter, Burnett, Patrick, and Olivadoti, Melissa
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Biomedical and Clinical Sciences ,Clinical Sciences ,Clinical Trials and Supportive Activities ,Clinical Research ,Child ,VP-102 ,cantharidin ,incidence ,infectious disease ,lesion ,molluscum ,molluscum contagiosum ,pediatric ,sensitive skin ,topical - Abstract
Trial registration>ClinicalTrials.gov identifier nos. NCT03377790 (for CAMP-1) and NCT03377803 (for CAMP-2).BackgroundVP-102 is drug-device combination product containing cantharidin (0.7% w/v) and has undergone Phase III clinical trials for the treatment of molluscum contagiosum (molluscum). Efficacy and safety may differ by body region due to variable skin anatomy.ObjectiveWe investigated the pooled safety and efficacy of VP-102 by affected body region.MethodsIndividuals at least two years of age with molluscum were randomized to topical VP-102 or vehicle once every 21 days until clear (maximum of four applications). Participants were assigned to body region groups where lesions were present at baseline. Body region lesion counts were recorded at each visit. Efficacy was measured by the percentage of participants with complete clearance of lesions by region. Pre-specified adverse events (AEs) were analyzed for those treated in the region on that visit.ResultsParticipants had a mean of two regions affected at baseline. Complete clearance was significantly higher in the VP-102-treated group than with vehicle application in all regions at the last visit (P
- Published
- 2021
237. Hematopoietic cell transplantation for DOCK8 deficiency: Results from a prospective clinical trial
- Author
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Freeman, Alexandra F., Gonzalez, Corina E., Yates, Bonnie, Cole, Kristen, Little, Lauren, Flannelly, Erin, Steinberg, Seth M., Mo, George, Piette, Nicole, Hughes, Thomas E., Cuellar-Rodriguez, Jennifer, Gea-Banacloche, Juan, Heller, Theo, Hammoud, Dima A., Holland, Steve M., Kong, Heidi H., Young, Fernanda D., Jing, Huie, Kayaoglu, Basak, Su, Helen C., Pai, Sung-Yun, Hickstein, Dennis D., and Shah, Nirali N.
- Published
- 2024
- Full Text
- View/download PDF
238. Blue and white light emissions and energy transfer in Tm3+ and Dy3+/Tm3+ doped lithium-aluminum-zinc phosphate glasses
- Author
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Huerta, E.F., Buendía-Rodríguez, J., González-Suárez, E., Meza-Rocha, A.N., Milan, E., Speghini, A., and Caldiño, U.
- Published
- 2024
- Full Text
- View/download PDF
239. Exposures and Bladder Cancer Risk Among Military Veterans: A Systematic Review and Meta-analysis
- Author
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Kronstedt, Shane, Cathey, Jackson, Chiu, Cedrick B., Saffati, Gal, Hinojosa-Gonzalez, David E., Rakic, Nikola, Patel, Sagar R., Lyon, Gabrielle, Srikishen, Neel, Taylor, Jennifer M., Slawin, Jeremy, and Jones, Jeffrey A.
- Published
- 2024
- Full Text
- View/download PDF
240. A New Paradigm in the Management of Scalp Pruritus: Findings From the SCALP-PR Trial
- Author
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Guerra-Tapia, A., González-Guerra, E., and Molinero Caturla, J.
- Published
- 2024
- Full Text
- View/download PDF
241. Liraglutide improves adipose tissue remodeling and mitochondrial dynamics in a visceral obesity model induced by a high-fat diet
- Author
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Touceda, Vanessa, Fontana Estevez, Florencia, Cacciagiú, Leonardo, Finocchietto, Paola, Bustos, Romina, Vidal, Agustina, Berg, Gabriela, Morales, Celina, González, Germán E., and Miksztowicz, Veronica
- Published
- 2024
- Full Text
- View/download PDF
242. [Translated article] The configuration of the screws in the osteosynthesis of fractures of the femoral neck does not influence the functional or mechanical outcomes
- Author
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Miralles Muñoz, F.A., Farrer Muñoz, P., Albero Catalá, L., de la Pinta Zazo, C., González Salas, E., and Pineda Salazar, M.
- Published
- 2024
- Full Text
- View/download PDF
243. Effect of hydrogen gas and leaching solution on the fast release of fission products from two PWR fuels
- Author
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Mennecart, T., Iglesias, L., Herm, M., König, T., Leinders, G., Cachoir, C., Lemmens, K., Verwerft, M., Metz, V., González-Robles, E., Meert, K., Vandoorne, T., and Gaggiano, R.
- Published
- 2024
- Full Text
- View/download PDF
244. Vertically distinct sources modulate stable isotope signatures and distribution of Mesozooplankton in central Patagonia: The Golfo de Penas - Baker Channel connection and analogies with the Beagle Channel
- Author
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Castro, Leonardo R., Soto-Mendoza, Samuel, Riccialdelli, Luciana, Presta, María L., Barrientos, Pamela, González, Humberto E., Daneri, Giovanni, Gutiérrez, Marcelo, Montero, Paulina, Masotti, Italo, and Díez, Beatriz
- Published
- 2024
- Full Text
- View/download PDF
245. The Effects of a Science and Social Studies Content Rich Shared Reading Intervention on the Vocabulary Learning of Preschool Dual Language Learners
- Author
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Gonzalez, Jorge E., Kim, Hanjoe, Anderson, Jacqueline, and Pollard-Durodola, Sharolyn
- Published
- 2024
- Full Text
- View/download PDF
246. Latin America Research Output Within the Top 5 Vascular Surgery Journals
- Author
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Gonzalez-Urquijo, Mauricio, Hinojosa-Gonzalez, David E., Padilla-Armendariz, Diana Paola, and Fabiani, Mario Alejandro
- Published
- 2024
- Full Text
- View/download PDF
247. La configuración de los tornillos en la osteosíntesis de las fracturas del cuello femoral no influye en los resultados funcionales ni mecánicos
- Author
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Miralles Muñoz, F.A., Farrer Muñoz, P., Albero Catalá, L., de la Pinta Zazo, C., González Salas, E., and Pineda Salazar, M.
- Published
- 2024
- Full Text
- View/download PDF
248. Evaluación de la intervención de fisioterapia en los pacientes con sarcopenia y fractura de cadera: una revisión sistemática
- Author
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Marrero-Morales, P.A., Hernández Gutierrez, M.F., Acosta Perez, P., Vera Arce, P., and González-Dávila, E.
- Published
- 2024
- Full Text
- View/download PDF
249. High prevalence of hepatitis A and E viruses in environmental and clinical samples from West Argentina
- Author
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Castro, Ivana Lo, Espul, Carlos, de Paula, Vanessa Salete, Altabert, Nancy R., Gonzalez, Jorge E., Lago, Barbara Vieira, and Villar, Livia Melo
- Published
- 2023
- Full Text
- View/download PDF
250. Sovereign Risk and Economic Complexity
- Author
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Gomez-Gonzalez, Jose E., primary, Uribe, Jorge M., additional, and Valencia, Oscar, additional
- Published
- 2024
- Full Text
- View/download PDF
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