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The Beam Energy Scan phase II (BES-II), performed in the Relativistic Heavy Ion Collider (RHIC) from 2019 to 2021, explored the phase transition between quark-gluon plasma and hadronic gas. BES-II exceeded the goal of a fourfold increase in the average luminosity over that achieved during Beam Energy Scan phase I (BES-I), at five gold beam energies: 9.8, 7.3, 5.75, 4.59, and 3.85 GeV/nucleon. This was accomplished by addressing several beam dynamics effects, including intrabeam scattering, beam-beam, space charge, beam instability, and field errors induced by superconducting magnet persistent currents. Some of these effects are especially detrimental at low energies. BES-II achievements are presented, and the measures taken to improve RHIC performance are described. These measures span the whole RHIC complex, including ion beam sources, injectors, beam lifetime improvements in RHIC, and operation with the world’s first bunched beam Low Energy RHIC electron Cooler (LEReC).

Rehabilitation is important for patients with coronavirus disease 2019 (COVID-19) infection. Given the lack of guidelines in English on the rehabilitation of these patients, we conducted a review of the most recent reports. We performed this literature review using the principal research databases and included randomized trials, recommendations, quasi-randomized or prospective controlled clinical trials, reports, guidelines, field updates, and letters to the editor. We identified 107 studies in the database search, among which 85 were excluded after screening the full text or abstract. In total, 22 studies were finally included. The complexity of the clinical setting and the speed of spread of the severe acute respiratory syndrome coronavirus 2, which leads to rapid occupation of beds in the intensive care unit, make it necessary to discharge patients with COVID-19 who have mild symptoms as soon as possible. For these reasons, it is necessary to formulate rehabilitation programs for these patients, to help them restore physical and respiratory function and to reduce anxiety and depression, particularly patients with comorbidities and those who live alone or in rural settings, to restore a good quality of life.

BACKGROUND: The present study was designed to investigate the effect of albusin B on lipid metabolism and antioxidant defense in broiler chickens by a proteomic approach. The bacteriocin, albusin B of Ruminococcus albus 7, expressed by yeast was applied in this study. Three dietary treatments, consisting of the basal diet (control), basal diet + albusin B (2.5 g kg−1), and basal diet + nosiheptide (2.5 mg kg−1) were randomly fed to 90 broiler chickens from 1 to 35 days of age, respectively. After 35 days of supplementation, the growth performance, lipid metabolism and antioxidant proteins in the jejunum and liver, intestinal protein profile, and plasma lipid profile were analyzed. RESULTS: Broilers with albusin B supplementation had greater body weight than the control broilers. Compared with the control broilers, lower triglyceride and higher high-density lipoprotein concentration in the blood were observed in both broilers with albusin B and nosiheptide supplementation. In addition, albusin B suppressed the mRNA expression of fatty acid binding protein 2 and ATP binding cassette transporter G 5 in the jejunum. In the jejunal protein profiles, four antioxidant proteins were upregulated by albusin B and nosiheptide treatments. The jejunal antioxidant gene expression had a concordant pattern. Hepatic genes related to lipid metabolism, 3-hydroxy-3-methyl-glutaryl CoA reductase, and superoxide dismutase were upregulated by albusin B supplementation. CONCLUSION: Albusin B supplementation modulated lipid metabolism and activated systemic antioxidant defense, which might partially contribute to the performance of broiler chickens. Copyright © 2012 Society of Chemical Industry [ABSTRACT FROM AUTHOR]

Abstract: The effect of promoter addition on activity of CeO2/γ-Al2O3 was assessed via the CWAO of phenol. Adding Cu as the promoter rendered the most effective performance, followed by Mn, although the performance of Mn-promoted catalyst was inferior to CeO2/γ-Al2O3. Mineralization of phenol was effectively implemented at 160°C using Cu-promoted catalyst (Ce15Cu5). Furthermore, at 180°C this catalyst produced about 100% conversion of phenol (1h) and 95% removal of chemical oxygen demand (4h), higher than that of CeO2/γ-Al2O3. In contrast, Mn-promoted catalyst (Ce15Mn5) required a temperature above 220°C for acceptable performance. Activity of re-used catalyst declined noticeably, due to deposits of carbonaceous compounds and leaching of metal ions. Regeneration with acetone rinsing after the first run was effective in recovering activity of Ce15Cu5, although after a second run further regeneration with acetone rinsing had only a moderate effect, due to residual carbonaceous deposits and the additive effect of leached metal species in each run. As an alternative to acetone, HCl or HNO3 solution (0.01M) was less effective at regenerating activity. In promoted catalysts, leached metal ions accounted for the majority of mineralization of phenol, while the solid catalyst played a dual role of initiator and terminator of free radicals. Despite a superior catalytic performance, leaching of Cu2+ from the promoted catalyst caused a severe decline in activity and poses the problem of secondary pollution of treated wastewater. Therefore, addition of Cu, as well as other metal species, is unfavorable in promoting the CeO2/γ-Al2O3 catalyst. [Copyright &y& Elsevier]

Background Many studies have assessed the impact of caregivers' work activities on the caregiver. There is growing concern about the ever-increasing problems, both physical and physiological, faced by health care workers who provide care for the ill and incapacitated. Aim The aim of the study was to examine what, if any, differences exist between male and female caregivers. This study primarily focused on caregivers who were taking care of a family member. Method Three hundred and eighty-eight caregivers (280 females and 108 males) were recruited from 16 randomly selected home-care agencies in Southern Taiwan. The participants completed the Chinese Health Questionnaire-12 and the Self-Rated Health Scale. They also completed questionnaires drawn up specifically for the purpose of this study. Results Compared to the male caregivers, the female caregivers more often reported they suffered from symptoms of lack of well being, a decrease in psychosocial health and overall self-rated health. Conclusion The results reiterate the importance of considering gender differentiation in the caregiving role. Major differences were found in the extent to which negative health consequences were experienced by the male and female caregivers. The results suggest that caregivers, especially female caregivers, urgently require adequate professional health care assistance in order to reduce the negative physical and physiological effects of caregiving on the health caregiver. Copyright © 2005 John Wiley & Sons, Ltd. [ABSTRACT FROM AUTHOR]

Abstract: It has been shown that the CeO2/γ-Al2O3 catalyst is a feasible alternative to CeO2 for the catalytic wet air oxidation (CWAO) of phenol because it remains an effective catalyst and yet is cheaper to prepare. In this study, we found that the optimal cerium content in the CeO2/γ-Al2O3 catalyst was 20wt.%, regardless of catalyst loading. Furthermore, at 180°C, with a phenol concentration of 1000mgl−1, and an O2 partial pressure of 1.0MPa or 1.5MPa, the optimal catalyst loading was 3.0gl−1. The efficacy of CWAO of phenol improved with O2 partial pressure, although the effects of O2 pressure were more significant between 0.5MPa and 1.5MPa than between 1.5MPa and 2.0MPa. After 2h of reaction, approximately 100% phenol conversion and 80% total organic carbon (TOC) removal was recorded at 180°C, 1000mgl−1 of phenol and 3.0gl−1 of catalyst. Because these percentages subsequently leveled off, it is suggested that 2h is a suitable time over which to run the reaction. The efficacy of CWAO of phenol decreased as initial phenol concentration was raised (from 400 to 2500mgl−1), with the exception of phenol conversion after about 2h, for which 400mgl−1 produced the lowest phenol conversion figure. Higher phenol concentrations require both catalyst loading and O2 partial pressure to be increased to maintain high performance. For example, for 2000mgl−1 and 2500mgl−1 phenol, nearly 100% phenol conversion and 90% TOC removal after 4h of reaction at 180°C required 4.0gl−1 of catalyst and 2.0MPa. [Copyright &y& Elsevier]

Wet air oxidation of a prepared reactive dye solution was performed to assess the efficacy of CoAlPO4-5 and CeO2 as catalysts in the reaction. Via adsorption and oxidation of dye, CoAlPO4-5 effectively decreased American Dye Manufacturers Institute and chemical oxygen demand (COD) values in the dye solution. At a reaction temperature of 135 °C and an applied pressure of 1.0 MPa, color and COD removal were as high as 95% and 90%, respectively, after 2 h. Active sites on the outer surface of CoAlPO4-5 are responsible for adsorption and decomposition of dye while active sites in the pores dominate further destruction and oxidation of intermediate products. Since the outer surface only represents a minor part of the total surface, the color removal does not increase appreciably with loading of CoAlPO4-5. The CeO2 catalyst, calcined from cerium chloride under high thermal impact (type A CeO2) was very effective in removing color and COD from the solution. This catalyst demonstrated near 100% color removal at temperatures above 135 °C and the COD removal could be above 95% at 165 °C. With both CoAlPO4-5 and CeO2 catalysts, COD rose and then fell back during the reaction, a feature typical of a consecutive reaction. In contrast to prepared CeO2, a commercial CeO2 did not exhibit any catalytic ability for the removal of color and COD. The durability of both CoAlPO4-5 and prepared CeO2 is considered to be fair. [Copyright &y& Elsevier]

Some results obtained with the use of Monte Carlo mathematical simulation of radiation transport in Timepix hybrid detectors based on chromium compensated gallium arsenide are presented in this contribution. The MCNPX, GEANT4, SRIM and MCCM code systems were used for this purpose. The in-depth profiles of the deposited energy by the incident photons within the sensor active volume, the shapes and dimensions of the generated charge carriers clouds for different incident energies and specific geometrical conditions were obtained and presented. The 22Ne ions ranges in the target material for two different energies and the contributions of each energy loss channel were also determined. Finally, for a selected detector irradiated with photons of different energies, the displacement cross sections for each chemical element in the active material, as well as the number of displacements per atoms produced for each atomic species were calculated.

Biomass is a very important forest resource in Andalusia. “Forest Biomass in Andalusia” web tool, developed by the Andalusian Government, provides information about the location and biomass stock for the main pine forest species. It is important to mention that information needs to be regularly, quickly, effectively and inexpensively updated. These requirements could be covered with the help of Earth Observation technologies. In this project, radar images have been acquired from ALOS-PALSAR sensor from different years (2008 and 2010) over two pilot areas located in Huelva. The aim of the study has been to develop a methodology to estimate wood volumes based on the statistic correlation between radar signal and wood volume, variable extracted of forest management plans contemporary to images. As result, correlations of 0.8 and 0.7 have been obtained for pine and eucalyptus respectively. Forest biomass has been calculated using species-specific allometric equations. Three key sources of information have been used: a sample of plots distributed homogeneously, an accurate digital terrain model and a current forest map. Furthermore, the study of the variability of estimated volumes between these dates has been carried out. Methodologies obtained could be extrapolated to the whole region.

A high-current high-brightness electron accelerator for low-energy RHIC electron cooling (LEReC) was successfully commissioned at Brookhaven National Laboratory. The LEReC accelerator includes a dc photoemission gun, a laser system, a photocathode delivery system, magnets, beam diagnostics, a superconducting rf booster cavity, and a set of normal conducting rf cavities to provide enough flexibility to tune the beam in the longitudinal phase space. Cooling with nonmagnetized rf accelerated electron beams requires longitudinal corrections to obtain a small momentum spread while preserving the transverse emittances. Electron beams with kinetic energies of 1.6 and 2.0 MeV with a beam quality suitable for cooling were successfully propagated through 100 m of beam lines, including dispersion sections, maintained through both cooling sections in RHIC and used for cooling ions in both RHIC rings simultaneously. The beam quality suitable for cooling RHIC beams was achieved in 2018, which led to the first experimental demonstration of bunched beam electron cooling of hadron beams in 2019.

Chemical cleaning is routinely performed in reverse osmosis (RO) plants for the regeneration of RO membranes that suffer from biofouling problems. The potential of urea as a chaotropic agent to enhance the solubilization of biofilm proteins has been reported briefly in the literature. In this paper the efficiency of urea cleaning for RO membrane systems has been compared to conventionally applied acid/alkali treatment. Preliminary assessment confirmed that urea did not damage the RO polyamide membranes and that the membrane cleaning efficiency increased with increasing concentrations of urea and temperature. Accelerated biofilm formation was carried out in membrane fouling simulators which were subsequently cleaned with (i) 0.01M sodium hydroxide (NaOH) and 0.1M hydrochloric acid (HCl) (typically applied in industry), (ii) urea (CO(NH2)2) and hydrochloric acid, or (iii) urea only (1340 g/Lwater). The pressure drop over the flow channel was used to evaluate the efficiency of the applied chemical cleanings. Biomass removal was evaluated by measuring chemical oxygen demand (COD), adenosine triphosphate (ATP), protein, and carbohydrate content from the membrane and spacer surfaces after cleaning. In addition to protein and carbohydrate quantification of the extracellular polymeric substances (EPS), fluorescence excitation−emission matrix (FEEM) spectroscopy was used to distinguish the difference in organic matter of the remaining biomass to assess biofilm solubilization efficacy of the different cleaning agents. Results indicated that two-stage CO(NH2)2/HCl cleaning was as effective as cleaning with NaOH/HCl in terms of restoring the feed channel pressure drop (>70% pressure drop decrease). One-stage cleaning with urea only was not as effective indicating the importance of the second-stage low pH acid cleaning in weakening the biofilm matrix. All three chemical cleaning protocols were equally effective in reducing the concentration of predominant EPS components protein and carbohydrate (>50% reduction in concentrations). However, urea-based cleaning strategies were more effective in solubilizing protein-like matter and tyrosine-containing proteins. Furthermore, ATP measurements showed that biomass inactivation was up to two-fold greater after treatment with urea-based chemical cleanings compared to the conventional acid/alkali treatment. The applicability of urea as an alternative, economical, eco-friendly and effective chemical cleaning agent for the control of biological fouling was successfully demonstrated. Keywords: Reverse osmosis, Biofouling, Membrane fouling simulator, Chemical cleaning, Urea

The following paper details the methodology for analyzing the potential of Unmanned Aerial Vehicles (UAV) as suitable observation platforms for obtaining thermal images of hunting areas, and for the estimation of number of individuals for these populations (fauna, in this case deer). Due to limitations detected in the initial information, some of the work stages are alternative approaches to an optimal process. On this basis, specific technical flight requirements are proposed in order to carry out a more appropriate analysis.

En el presente trabajo se describe la estructura y funcionamiento de un contador gamma para estudios de muestras con presencia de I-125.

La fístula quilosa, por daño del conducto torácico, aparece en el 1-2,5% de los pacientes sometidos a disección cervical. Las complicaciones asociadas incluyen desnutrición, compromiso inmune, formación de fístulas y necrosis cutánea con exposición carotídea, e incluso ruptura. De la literatura actual no se puede deducir ningún algoritmo de tratamiento definitivo, pero parece existir un consenso en realizar un manejo conservador de la mayoría de los casos. El manejo médico se basa en la teoría de que si se disminuye el flujo de quilo se permitirá el cierre espontáneo de la fístula, e incluye: drenaje conectado a vacío, reposo, vendaje compresivo (en discusión), intervención nutricional y uso de análogos de somatostatina. El manejo nutricional implica el uso de dietas bajas en grasa suplementadas con Triglicéridos de Cadena Media (MCT), Nutrición Enteral con TCM o Nutrición Parenteral total (NPT).Injury to the thoracic duct, leading to chyle leak, occurs in 1-2,5% of patients who undergo neck dissection. Associated complications include malnutrition, immune compromise, fistula formation and carotid blowout. No definitive treatment algorithm can be deduced from the current literature, but on last reviews, there is an agreement on the conservative management. Medical management is based on that decreasing chyle flow will allow for spontaneous closure of the chyle leak. Conservative treatment includes: closed vacuum drainage, bed-rest, nutrition modification and synthetic somatostatin analog. Nutrition modification involves a low-fat diet supplemented with medium-chain triglycerides (MCT), enteral nutrition with high percentage of MCT or parenteral nutrition.

An unusual presentation of Devic’s neuromyelitis optica (NMO) disease associated with bilateral internuclear ophthalmoplegia (INO) is described. A 32-year-old pregnant patient was diagnosed with NMO. First symptoms were headache and sudden visual loss in her right eye (RE). Eighteen months ago, she reported other neurologic symptoms such as paresthesia. Based on her visual field, fundoscopy and Ishihara test, she was diagnosed with retrobulbar neuritis of the RE. After delivery, new neurologic symptoms resembling transverse myelitis appeared. She was treated with methylprednisolone and plasmapheresis, which improved her visual acuity; however, a sudden bilateral INO appeared, with adduction defect and nystagmus with abduction in both eyes. No improvement was obtained after treatment with azathioprine and rituximab. Paresis of the legs and the right arm persisted, but double vision and OIN gradually disappeared. At the end, the patient had a residual exophoria in the RE and nystagmus with abduction in the left eye. Prevalence of NMO is lower than one case per one million inhabitants, and it is not likely to affect the encephalic trunk; furthermore, bilateral INO in NMO is rare. Two major criteria and at least two of the three minor ones are required to confirm a NMO diagnosis, and our patient fulfilled these diagnosis criteria.

Superconducting rf (SRF) photoinjectors are one of the most promising devices for generating continuous wave (CW) electron beams with record high brightness. Ultrahigh vacuum of SRF guns provides for long lifetime of the high quantum efficiency (QE) photocathodes, while SRF technology provides for high accelerating gradients exceeding 10 MV/m. It is especially true for low frequency SRF guns where electrons are generated at photocathodes at the crest of accelerating voltage. Two main physics challenges of SRF guns are their compatibility with high QE photocathodes and multipacting. The first is related to a possibility of deposition of photocathode materials (such as Cs) on the walls of the SRF cavity, which can result in increased dark current via reduction of the bulk Nb work function and in enhancing of a secondary electron emission yield (SEY). SEY plays critical role in multipacting (e.g., an exponential growth of the multipactor discharge), which could both spoil the gun vacuum and speed up the deposition of the cathode material on the walls of the SRF cavity. In short, the multipactor behavior in superconducting accelerating units must be well understood for successful operation of an SRF photo-injector. In this paper we present our studies of 1.2 MV 113 MHz quarter-wave SRF photoinjector serving as a source of electron beam for the coherent electron cooling experiment (CeC) at BNL. During three years of operating our SRF gun we encountered a number of multipacting zones. We also observed that presence of CsK_{2}Sb photocathode in the gun could create additional multipacting barriers. We had conducted a comprehensive numerical and experimental study of the multipactor discharge in our SRF gun. We had developed a process of crossing the multipacting barriers from zero to the operational voltage without affecting the lifetime of our photocathode and enhancing the strength of multipacting barriers. We found a good agreement between the results of simulations and our experimental data.

Multi-model ensemble climate projections in the ENSEMBLES Project of the EU allowed the authors to quantify selected extreme-weather indices for Poland, of importance to climate impacts on systems and sectors. Among indices were: number of days in a year with high value of the heat index; with high maximum and minimum temperatures; length of vegetation period; and number of consecutive dry days. Agricultural, hydrological, and human health indices were applied to evaluate the changing risk of weather extremes in Poland in three sectors. To achieve this, model-based simulations were compared for two time horizons, a century apart, i.e., 1961–1990 and 2061–2090. Climate changes, and in particular increases in temperature and changes in rainfall, have strong impacts on agriculture via weather extremes – droughts and heat waves. The crop yield depends particularly on water availability in the plant development phase. To estimate the changes in present and future yield of two crops important for Polish agriculture i.e., potatoes and wheat, some simple empirical models were used. For these crops, decrease of yield is projected for most of the country, with national means of yield change being: –2.175 t/ha for potatoes and –0.539 t/ha for wheat. Already now, in most of Poland, evapotranspiration exceeds precipitation during summer, hence the water storage (in surface water bodies, soil and ground) decreases. Summer precipitation deficit is projected to increase considerably in the future. The additional water supplies (above precipitation) needed to use the agro-potential of the environment would increase by half. Analysis of water balance components (now and in the projected future) can corroborate such conclusions. As regards climate and health, a composite index, proposed in this paper, is a product of the number of senior discomfort days and the number of seniors (aged 65+). The value of this index is projected to increase over 8-fold during 100 years. This is an effect of both increase in the number of seniors (over twofold) and the number of senior-discomfort days (nearly fourfold).

Purpose. To evaluate the dose effect of vitamin K3 on wound healing mechanisms. Methods. Conjunctival fibroblasts were incubated for 24 hours. An artificial wound was made and the cells were incubated with fresh medium plus doses of vitamin K3 to be tested. Wound repair was monitored at 0, 18, 24, and 48 hours. Proliferation was measured in actively dividing cells by [3H]thymidine uptake. Six different groups were tested: group 1/no drugs added, group 2/ethanol 0.1%, group 3/vitamin K3 1 mg/L, group 4/vitamin K3 2 mg/L, group 5/vitamin K3 4 mg/L, and group 6/vitamin K3 6 mg/L. Each experiment was carried out in triplicate and 4 times. Results. There were no differences among groups at the initial time. In vitro wound repair was slower in groups 4, 5, and 6. There were no differences between control and ethanol groups and between control and vitamin K3 1 mg/L groups. Fibroblast mitogenic activity was statistically decreased in all vitamin K groups; statistical differences were found among vitamin K3 1 mg/mL and higher doses too. In groups 5 and 6, cellular toxicity was presented. Conclusions. Vitamin K3 is able to inhibit fibroblast proliferation. Vitamin K3 2 mg/L or higher doses inhibit wound healing repair, exhibiting cellular toxicity at 4 and 6 mg/L.

Agastache foeniculum (Pursh) Kuntz is a perennial, herbaceous medicinal and spice member of Lamiaceae family. It has an anise-like scented essential oil which is mainly biosynthesized in the leaves and flowers of the decorative plant. It has been reported that the leaves and inflorescences of this plant to be used in herbal teas, cakes, sweets, salads and desserts also the leaves to be used for treating heart conditions, chest pain, for inducing sweating to reduce fever and in poultices. Using separate machine RETSCH AS 300, we tried separating the seed grain than hes mall grain species Agastache foeniculum (Pursh) Kuntz. During the screening factor (5 minutes) is negative compared to the control, separation than small seeds. Amplitude factor and a very positive influence on the amount of seed remaining on the sieve than 1.

Taxonomical evaluation of six taxa of the Achillea aggregate was carried out to determine their potential for breeding and cultivation. We used complex morphological, cytological and chemical aspects of characterisation. Three taxa of tetraploid genom and high chamazulene contents (33-40% ess.oil) proved to be A. collina Becker. A strain of wild origin had also high -bisabolol content and high oil level, comparable with the selected cultivars. A population was identified as new chemotype of A. pannonica Scheele with typical morphological and cytological traits, a wide sesquiterpene spectrum but lacking of 1.8 cineole and -pinene. We found a mixed population which consisted of both A. collina and A. pannonica plants. A tetraploid, azuleneless taxon could be concluded as A. pratensis Saukel and Langer not described before in Hungary. The diverse performance of the populations calls the attention to the significance of controlled plant raw in phytopharmaceutical products.