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1,534 results on '"Jiménez‐Murcia, Susana"'

202. Impulsive Personality Traits Predicted Weight Loss in Individuals with Type 2 Diabetes after 3 Years of Lifestyle Interventions

Author

Testa, Giulia, primary, Camacho-Barcia, Lucía, additional, Gómez-Martínez, Carlos, additional, Mora-Maltas, Bernat, additional, de la Torre, Rafael, additional, Pintó, Xavier, additional, Corella, Dolores, additional, Granero, Roser, additional, Cuenca-Royo, Aida, additional, Jiménez-Murcia, Susana, additional, Babio, Nancy, additional, Fernández-Carrión, Rebeca, additional, Esteve-Luque, Virginia, additional, Forcano, Laura, additional, Ni, Jiaqi, additional, Malcampo, Mireia, additional, De las Heras-Delgado, Sara, additional, Fitó, Montse, additional, Salas-Salvadó, Jordi, additional, and Fernández-Aranda, Fernando, additional

Published
2022
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203. Motherhood and Treatment Outcome in Female Patients with Compulsive Buying–Shopping Disorder

Author

Mestre-Bach, Gemma, primary, Granero, Roser, additional, Casalé-Salayet, Gemma, additional, Fernández-Aranda, Fernando, additional, Müller, Astrid, additional, Brand, Matthias, additional, Gómez-Peña, Mónica, additional, Moragas, Laura, additional, Sánchez, Isabel, additional, Camacho-Barcia, Lucía, additional, Villena, Alejandro, additional, Lara-Huallipe, Milagros L., additional, and Jiménez-Murcia, Susana, additional

Published
2022
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204. Compulsive Sexual Behavior Online and Non-online in Adult Male Patients and Healthy Controls: Comparison in Sociodemographic, Clinical, and Personality Variables

Author

González-Bueso, Vega, primary, Santamaría, Juan José, additional, Caro-Pérez, Oriol, additional, Fernández, Daniel, additional, Baño-Alcazar, Marta, additional, Jiménez-Murcia, Susana, additional, Håkansson, Anders, additional, del Pino-Gutiérrez, Amparo, additional, and Ribas, Joan, additional

Published
2022
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205. Food addiction in eating disorders: a cluster analysis approach and treatment outcome

Author

Munguía, Lucero, Gaspar-Pérez, Anahí, Jiménez-Murcia, Susana, Granero, Roser, Sánchez, Isabel, Vintró-Alcaraz, Cristina, Diéguez, Carlos, Gearhardt, Ashley N., Fernández-Aranda, Fernando, Institut d'Investigació Biomèdica de Bellvitge. Psiconeurobiologia dels Trastorns de la Conducta Alimentària i Conductes Addictives, Hospital Universitari de Bellvitge. Psiconeurobiologia dels Trastorns de la Conducta Alimentària i Conductes Addictives, Universidad de Santiago de Compostela. Departamento de Psicologia, Universidad de Santiago de Compostela. Centro Singular de Investigación en Medicina Molecular y Enfermedades Crónicas (CiMUS), and Universitat de Barcelona. Departament de Ciències Clíniques

Subjects
food addiction, eating disorders, treatment outcome, cluster analysis approach, Nutrition and Dietetics, Food addiction, Anàlisi de conglomerats, Feeding and Eating Disorders, Treatment Outcome, Cluster analysis, Cluster analysis approach, Eating disorders, Cluster Analysis, Humans, Food Addiction, Treatment outcome, Bulímia, Bulimia, Bulimia Nervosa, Trastorns de la conducta alimentària, Food Science
Abstract

Background: A first approach of a phenotypic characterization of food addiction (FA) found three clusters (dysfunctional, moderate and functional). Based on this previous classification, the aim of the present study is to explore treatment responses in the sample diagnosed with Eating Disorder(ED) of different FA profiles. Methods: The sample was composed of 157 ED patients with FA positive, 90 with bulimia nervosa (BN), 36 with binge eating disorder (BED), and 31 with other specified feeding or eating disorders (OSFED). Different clinical variables and outcome indicators were evaluated. Results: The clinical profile of the clusters present similar characteristics with the prior study, having the dysfunctional cluster the highest ED symptom levels, the worse psychopathology global state, and dysfunctional personality traits, while the functional one the lowest ED severity level, best psychological state, and more functional personality traits. The dysfunctional cluster was the one with lowest rates of full remission, the moderate one the higher rates of dropouts, and the functional one the highest of full remission. Conclusions: The results concerning treatment outcome were concordant with the severity of the FA clusters, being that the dysfunctional and moderate ones had worst treatment responses than the functional one.

Published
2022

207. Common Genetic Variation and Age of Onset of Anorexia Nervosa

Author

Watson, Hunna J., Thornton, Laura M., Yilmaz, Zeynep, Baker, Jessica H., Coleman, Jonathan R.I., Adan, Roger A.H., Alfredsson, Lars, Andreassen, Ole A., Ask, Helga, Berrettini, Wade H., Boehnke, Michael, Boehm, Ilka, Boni, Claudette, Buehren, Katharina, Bulant, Josef, Burghardt, Roland, Chang, Xiao, Cichon, Sven, Cone, Roger D., Courtet, Philippe, Crow, Scott, Crowley, James J., Danner, Unna N., de Zwaan, Martina, Dedoussis, George, DeSocio, Janiece E., Dick, Danielle M., Dikeos, Dimitris, Dina, Christian, Djurovic, Srdjan, Dmitrzak-Weglarz, Monika, Docampo-Martinez, Elisa, Duriez, Philibert, Egberts, Karin, Ehrlich, Stefan, Eriksson, Johan G., Escaramís, Geòrgia, Esko, Tõnu, Estivill, Xavier, Farmer, Anne, Fernández-Aranda, Fernando, Fichter, Manfred M., Föcker, Manuel, Foretova, Lenka, Forstner, Andreas J., Frei, Oleksandr, Gallinger, Steven, Giegling, Ina, Giuranna, Johanna, Gonidakis, Fragiskos, Gorwood, Philip, Gratacòs, Mònica, Guillaume, Sébastien, Guo, Yiran, Hakonarson, Hakon, Hauser, Joanna, Havdahl, Alexandra, Hebebrand, Johannes, Helder, Sietske G., Herms, Stefan, Herpertz-Dahlmann, Beate, Herzog, Wolfgang, Hinney, Anke, Hübel, Christopher, Hudson, James I., Imgart, Hartmut, Jamain, Stephanie, Janout, Vladimir, Jiménez-Murcia, Susana, Jones, Ian R., Julià, Antonio, Kalsi, Gursharan, Kaminská, Deborah, Kaprio, Jaakko, Karhunen, Leila, Kas, Martien J.H., Keel, Pamela K., Kennedy, James L., Keski-Rahkonen, Anna, Kiezebrink, Kirsty, Klareskog, Lars, Klump, Kelly L., Knudsen, Gun Peggy S., La Via, Maria C., Le Hellard, Stephanie, Leboyer, Marion, Li, Dong, Lilenfeld, Lisa, Lin, Bochao, Lissowska, Jolanta, Luykx, Jurjen, Magistretti, Pierre, Maj, Mario, Marsal, Sara, Marshall, Christian R., Mattingsdal, Morten, Meulenbelt, Ingrid, Micali, Nadia, Mitchell, Karen S., Monteleone, Alessio Maria, Monteleone, Palmiero, Myers, Richard, Navratilova, Marie, Ntalla, Ionna, O'Toole, Julie K., Ophoff, Roel A., Padyukov, Leonid, Pantel, Jacques, Papežová, Hana, Pinto, Dalila, Raevuori, Anu, Ramoz, Nicolas, Reichborn-Kjennerud, Ted, Ricca, Valdo, Ripatti, Samuli, Ripke, Stephan, Ritschel, Franziska, Roberts, Marion, Rotondo, Alessandro, Rujescu, Dan, Rybakowski, Filip, Scherag, André, Scherer, Stephen W., Schmidt, Ulrike, Scott, Laura J., Seitz, Jochen, Silén, Yasmina, Šlachtová, Lenka, Slagboom, P. Eline, Slof-Op ‘t Landt, Margarita C.T., Slopien, Agnieszka, Sorbi, Sandro, Świątkowska, Beata, Tortorella, Alfonso, Tozzi, Federica, Treasure, Janet, Tsitsika, Artemis, Tyszkiewicz-Nwafor, Marta, Tziouvas, Konstantinos, van Elburg, Annemarie A., van Furth, Eric F., Walton, Esther, Widen, Elisabeth, Zerwas, Stephanie, Zipfel, Stephan, Bergen, Andrew W., Boden, Joseph M., Brandt, Harry, Crawford, Steven, Halmi, Katherine A., Horwood, L. John, Johnson, Craig, Kaplan, Allan S., Kaye, Walter H., Mitchell, James E., Olsen, Catherine M., Pearson, John F., Pedersen, Nancy L., Strober, Michael, Werge, Thomas, Whiteman, David C., Woodside, D. Blake, Gordon, Scott, Maguire, Sarah, Larsen, Janne T., Parker, Richard, Petersen, Liselotte V., Jordan, Jennifer, Kennedy, Martin, Wade, Tracey D., Birgegård, Andreas, Lichtenstein, Paul, Landén, Mikael, Martin, Nicholas G., Mortensen, Preben Bo, Breen, Gerome, Bulik, Cynthia M., Watson, Hunna J., Thornton, Laura M., Yilmaz, Zeynep, Baker, Jessica H., Coleman, Jonathan R.I., Adan, Roger A.H., Alfredsson, Lars, Andreassen, Ole A., Ask, Helga, Berrettini, Wade H., Boehnke, Michael, Boehm, Ilka, Boni, Claudette, Buehren, Katharina, Bulant, Josef, Burghardt, Roland, Chang, Xiao, Cichon, Sven, Cone, Roger D., Courtet, Philippe, Crow, Scott, Crowley, James J., Danner, Unna N., de Zwaan, Martina, Dedoussis, George, DeSocio, Janiece E., Dick, Danielle M., Dikeos, Dimitris, Dina, Christian, Djurovic, Srdjan, Dmitrzak-Weglarz, Monika, Docampo-Martinez, Elisa, Duriez, Philibert, Egberts, Karin, Ehrlich, Stefan, Eriksson, Johan G., Escaramís, Geòrgia, Esko, Tõnu, Estivill, Xavier, Farmer, Anne, Fernández-Aranda, Fernando, Fichter, Manfred M., Föcker, Manuel, Foretova, Lenka, Forstner, Andreas J., Frei, Oleksandr, Gallinger, Steven, Giegling, Ina, Giuranna, Johanna, Gonidakis, Fragiskos, Gorwood, Philip, Gratacòs, Mònica, Guillaume, Sébastien, Guo, Yiran, Hakonarson, Hakon, Hauser, Joanna, Havdahl, Alexandra, Hebebrand, Johannes, Helder, Sietske G., Herms, Stefan, Herpertz-Dahlmann, Beate, Herzog, Wolfgang, Hinney, Anke, Hübel, Christopher, Hudson, James I., Imgart, Hartmut, Jamain, Stephanie, Janout, Vladimir, Jiménez-Murcia, Susana, Jones, Ian R., Julià, Antonio, Kalsi, Gursharan, Kaminská, Deborah, Kaprio, Jaakko, Karhunen, Leila, Kas, Martien J.H., Keel, Pamela K., Kennedy, James L., Keski-Rahkonen, Anna, Kiezebrink, Kirsty, Klareskog, Lars, Klump, Kelly L., Knudsen, Gun Peggy S., La Via, Maria C., Le Hellard, Stephanie, Leboyer, Marion, Li, Dong, Lilenfeld, Lisa, Lin, Bochao, Lissowska, Jolanta, Luykx, Jurjen, Magistretti, Pierre, Maj, Mario, Marsal, Sara, Marshall, Christian R., Mattingsdal, Morten, Meulenbelt, Ingrid, Micali, Nadia, Mitchell, Karen S., Monteleone, Alessio Maria, Monteleone, Palmiero, Myers, Richard, Navratilova, Marie, Ntalla, Ionna, O'Toole, Julie K., Ophoff, Roel A., Padyukov, Leonid, Pantel, Jacques, Papežová, Hana, Pinto, Dalila, Raevuori, Anu, Ramoz, Nicolas, Reichborn-Kjennerud, Ted, Ricca, Valdo, Ripatti, Samuli, Ripke, Stephan, Ritschel, Franziska, Roberts, Marion, Rotondo, Alessandro, Rujescu, Dan, Rybakowski, Filip, Scherag, André, Scherer, Stephen W., Schmidt, Ulrike, Scott, Laura J., Seitz, Jochen, Silén, Yasmina, Šlachtová, Lenka, Slagboom, P. Eline, Slof-Op ‘t Landt, Margarita C.T., Slopien, Agnieszka, Sorbi, Sandro, Świątkowska, Beata, Tortorella, Alfonso, Tozzi, Federica, Treasure, Janet, Tsitsika, Artemis, Tyszkiewicz-Nwafor, Marta, Tziouvas, Konstantinos, van Elburg, Annemarie A., van Furth, Eric F., Walton, Esther, Widen, Elisabeth, Zerwas, Stephanie, Zipfel, Stephan, Bergen, Andrew W., Boden, Joseph M., Brandt, Harry, Crawford, Steven, Halmi, Katherine A., Horwood, L. John, Johnson, Craig, Kaplan, Allan S., Kaye, Walter H., Mitchell, James E., Olsen, Catherine M., Pearson, John F., Pedersen, Nancy L., Strober, Michael, Werge, Thomas, Whiteman, David C., Woodside, D. Blake, Gordon, Scott, Maguire, Sarah, Larsen, Janne T., Parker, Richard, Petersen, Liselotte V., Jordan, Jennifer, Kennedy, Martin, Wade, Tracey D., Birgegård, Andreas, Lichtenstein, Paul, Landén, Mikael, Martin, Nicholas G., Mortensen, Preben Bo, Breen, Gerome, and Bulik, Cynthia M.

Abstract

Background: Genetics and biology may influence the age of onset of anorexia nervosa (AN). The aims of this study were to determine whether common genetic variation contributes to age of onset of AN and to investigate the genetic associations between age of onset of AN and age at menarche. Methods: A secondary analysis of the Psychiatric Genomics Consortium genome-wide association study (GWAS) of AN was performed, which included 9335 cases and 31,981 screened controls, all from European ancestries. We conducted GWASs of age of onset, early-onset AN (<13 years), and typical-onset AN, and genetic correlation, genetic risk score, and Mendelian randomization analyses. Results: Two loci were genome-wide significant in the typical-onset AN GWAS. Heritability estimates (single nucleotide polymorphism–h2) were 0.01–0.04 for age of onset, 0.16–0.25 for early-onset AN, and 0.17–0.25 for typical-onset AN. Early- and typical-onset AN showed distinct genetic correlation patterns with putative risk factors for AN. Specifically, early-onset AN was significantly genetically correlated with younger age at menarche, and typical-onset AN was significantly negatively genetically correlated with anthropometric traits. Genetic risk scores for age of onset and early-onset AN estimated from independent GWASs significantly predicted age of onset. Mendelian randomization analysis suggested a causal link between younger age at menarche and early-onset AN. Conclusions: Our results provide evidence consistent with a common variant genetic basis for age of onset and implicate biological pathways regulating menarche and reproduction.

Published
2022

208. Delay Discounting in Gambling Disorder : Implications in Treatment Outcome

Author

Mena-Moreno, Teresa, Testa, Giulia, Mestre-Bach, Gemma, Miranda-Olivos, Romina, Granero, Roser, Fernández-Aranda, Fernando, Menchón, José M., Jiménez-Murcia, Susana, Mena-Moreno, Teresa, Testa, Giulia, Mestre-Bach, Gemma, Miranda-Olivos, Romina, Granero, Roser, Fernández-Aranda, Fernando, Menchón, José M., and Jiménez-Murcia, Susana

Abstract

Altres ajuts: Delegación del Gobierno para el Plan Nacional sobre Drogas: 2017I067 i 2019I47, Impulsive choice, measured by delay discounting (DD) tasks, has been shown in patients with gambling disorders (GD). However, the impact of DD and treatment outcome has been scarcely explored in GD patients. The aims of this study were: (1) to examine the baseline association between DD and clinical variables in GD patients depending on their age and gambling preferences (strategic vs. non-strategic); and (2) to estimate the predictive role of DD on poorer outcomes of cognitive-behavioral therapy (CBT) when considering also the effect of other clinical variables. 133 treatment-seeking male GD patients were evaluated at baseline with a DD task and measures of GD severity, personality traits and psychopathology. Treatment outcome was measured in terms of dropout from CBT and relapses. Results showed baseline associations between DD and GD severity (correlation coefficient R = 0.408 among strategic gamblers and R = 0.279 among mixed gamblers) and between DD and positive/negative urgency (R = 0.330 for the youngest patients, R = 0.244 for middle age, and around R = 0.35 for gamblers who reported preferences for strategic games). Other personality traits such as high harm avoidance and low cooperativeness were also related to DD at baseline (R = 0.606 among strategic gamblers). Regarding treatment outcome, a steeper discount rate predicted a higher risk of relapses in strategic gamblers (odds ratio OR = 3.01) and middle-age ones (OR = 1.59), and a higher risk of dropout in younger gamblers (OR = 1.89), non-strategic gamblers (OR = 1.70) and mixed gamblers (R = 4.74). GD severity mediated the associations between age, DD, personality traits and poor CBT outcome. In conclusion, impulsive choice affects treatment response in individuals with GD and may interfere with it to a significant extent. Considering DD in GD, patients seeking treatment could help control its impact on treatment adherence and relapses.

Published
2022

209. The link between cognition and somatic conditions related to insulin resistance in the UK Biobank study cohort:a systematic review

Author

Fanelli, Giuseppe, Mota, Nina Roth, Salas-Salvadó, Jordi, Bulló, Mònica, Fernandez-Aranda, Fernando, Camacho-Barcia, Lucía, Testa, Giulia, Jiménez-Murcia, Susana, Bertaina-Anglade, Valérie, Franke, Barbara, Poelmans, Geert, van Gils, Veerle, Jansen, Willemijn J., Vos, Stephanie J.B., Wimberley, Theresa, Dalsgaard, Søren, Barta, Csaba, Serretti, Alessandro, Fabbri, Chiara, Bralten, Janita, Fanelli, Giuseppe, Mota, Nina Roth, Salas-Salvadó, Jordi, Bulló, Mònica, Fernandez-Aranda, Fernando, Camacho-Barcia, Lucía, Testa, Giulia, Jiménez-Murcia, Susana, Bertaina-Anglade, Valérie, Franke, Barbara, Poelmans, Geert, van Gils, Veerle, Jansen, Willemijn J., Vos, Stephanie J.B., Wimberley, Theresa, Dalsgaard, Søren, Barta, Csaba, Serretti, Alessandro, Fabbri, Chiara, and Bralten, Janita

Abstract

Clinical and genomic studies have shown an overlap between neuropsychiatric disorders and insulin resistance (IR)-related somatic conditions, including obesity, type 2 diabetes, and cardiovascular diseases. Impaired cognition is often observed among neuropsychiatric disorders, where multiple cognitive domains may be affected. In this review, we aimed to summarise previous evidence on the relationship between IR-related diseases/traits and cognitive performance in the large UK Biobank study cohort. Electronic searches were conducted on PubMed, Scopus, and Web of Science until April 2022. Eighteen articles met the inclusion criteria and were qualitatively reviewed. Overall, there is substantial evidence for an association between IR-related cardio-metabolic diseases/traits and worse performance on various cognitive domains, which is largely independent of possible confoundings. The most consistent findings referred to IR-related associations with poorer verbal and numerical reasoning ability, as well as slower processing speed. The observed associations might be mediated by alterations in immune-inflammation, brain integrity/connectivity, and/or comorbid somatic or psychiatric diseases/traits. Our findings provide impetus for further research into the underlying neurobiology and possible new therapeutic targets.

Published
2022

210. Compulsive sexual behavior online and non-online in adult male patients and healthy controls: comparison in sociodemographic, clinical, and personality variables

Author

Universitat Politècnica de Catalunya. Doctorat en Enginyeria Tèxtil i Paperera, Universitat Politècnica de Catalunya. Departament d'Estadística i Investigació Operativa, Universitat Politècnica de Catalunya. CELBIOTECH - Grup de Recerca: Enginyeria Paperera, Universitat Politècnica de Catalunya. GRBIO - Grup de Recerca en Bioestadística i Bioinformàtica, González Bueso, Vega, Santamaría, Juan José, Caro Pérez, Oriol, Fernández Martínez, Daniel, Baño-Alcazar, Marta, Jiménez Murcia, Susana, Hakansson, Anders, del Pino Gutiérrez, Amparo, Ribas, Joan, Universitat Politècnica de Catalunya. Doctorat en Enginyeria Tèxtil i Paperera, Universitat Politècnica de Catalunya. Departament d'Estadística i Investigació Operativa, Universitat Politècnica de Catalunya. CELBIOTECH - Grup de Recerca: Enginyeria Paperera, Universitat Politècnica de Catalunya. GRBIO - Grup de Recerca en Bioestadística i Bioinformàtica, González Bueso, Vega, Santamaría, Juan José, Caro Pérez, Oriol, Fernández Martínez, Daniel, Baño-Alcazar, Marta, Jiménez Murcia, Susana, Hakansson, Anders, del Pino Gutiérrez, Amparo, and Ribas, Joan

Abstract

Background and Aims: Compulsive sexual behavior (CSB) is characterized by a persistent pattern of failure to control sexual impulses, resulting in repetitive sexual behavior over a prolonged period that causes marked discomfort in personal, family, social, school, work or in other functional areas. The evolution of the worldwide incidence of this disorder warrants further studies focused on examining the characteristics of the affected people. The purpose of this study was to compare online compulsive sexual behavior (when the problematic sexual practices were online) and non-online compulsive sexual behavior (when the problematic sexual practices were in-person) patients (OCSB and non-OCSB, respectively), and healthy controls in terms of sexual behavior, sociodemographic variables and psychopathology and personality characteristics. Method: A sample of 80 CSB male patients consecutively admitted to our Behavioral Addictions Unit and 25 healthy male controls, participated in the study. The CSB group was comprised by 36 online CSB patients (mean age 42.25, SD: 10.0) and 44 non-online CSB patients (mean age 43.5, SD: 11.9). Scores on the Sexual Compulsivity Scale, Temperament and Character Inventory-Revised, Symptom CheckList-90 Items-Revised, State-Trait Anxiety Index, and additional demographic, clinical, and social/family variables related to sexual behaviors between the three groups were compared. Results: When compared with healthy controls, both clinical groups showed higher psychopathology in all measures as well as higher harm avoidance and self-transcendence and lower self-directness and cooperativeness. When comparing OCSB and non-OCSB patients, results showed that non-OCSB patients exhibited higher prevalence of sexually transmitted diseases, higher percentage of homosexual and bisexual orientation and higher scores in anxiety and in sexual impulse control failure. Conclusion: Both online and non-online CSB patients may experience a variety of comorbid psyc, "This work was funded by an AIS (Atención e Investigación en Socioaddiciones) intramural research program. This research was partially supported by Marsden grant E2987-3648 administrated by the Royal Society of New Zealand, by grant 2017 SGR 622 (GRBIO) administrated by the Departament d’Economia i Coneixement de la Generalitat de Catalunya (Spain), by the Ministerio de Ciencia eInnovación(Spain)[PID2019-104830RBI00/ DOI (AEI): 10.13039/501100011033], and by the FPI 2018 grant (Reference code: PRE2018-085388).", Peer Reviewed, Postprint (published version)

Published
2022

211. Actualización sobre los aspectos neurobiológicos, clínicos y de tratamiento sobre el juego patológico

Author

Solé-Morata, Neus, Fernández-Aranda, Fernando, Baenas, Isabel, Gómez-Peña, Mónica, Moragas, Laura, Lara-Huallipe, Milagros Lizbeth, Mora-Maltas, Bernat, Gaspar, Anahí, Camacho-Barcia, Lucía, Lucas, Ignacio, Munguía, Lucero, and Jiménez-Murcia, Susana

Abstract

El juego es una actividad cada vez más común en nuestra sociedad, especialmente con la aparición de nuevas modalidades de juego, que lo hacen más fácilmente accesible. A pesar de que para la mayoría de individuos jugar es solo un entretenimiento, algunas personas pueden desarrollar un trastorno de juego (TJ). En los últimos años, el interés por dicho trastorno ha ido aumentado tanto en la comunidad clínica como científica, y el número de estudios sobre etiopatogenia y factores de riesgo ha crecido significativamente. Entre los distintos factores hormonales en el desarrollo y mantenimiento del TJ destacan: la edad, el sexo masculino, tener un nivel socioeconómico bajo, niveles altos de impulsividad y baja regulación emocional. A nivel neurobiológico, se han descrito anomalías en los sistemas de neurotransmisión que regulan las conductas de recompensa. Asimismo, algunos estudios han demostrado la implicación de factores hormonales y en el desarrollo y mantenimiento del TJ. Todo esto ha contribuido notablemente en la mejora de las acciones de prevención y tratamiento. No obstante, aún quedan muchas cuestiones por resolver y es necesario seguir avanzando en la exploración de este trastorno. La presente revisión ofrece una actualización sobre los aspectos clínicos, neurobiológicos y de tratamiento del TJ.

Published
2023
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214. Suicide attempts in anorexia nervosa subtypes

Author

Forcano, Laura, Álvarez, Eva, Santamaría, Juan J., Jimenez-Murcia, Susana, Granero, Roser, Penelo, Eva, Alonso, Pino, Sánchez, Isabel, Menchón, Jose M., Ulman, Frances, Bulik, Cynthia M., and Fernández-Aranda, Fernando

Published
2011
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216. The Relationship of Shopping-Related Decisions with Materialistic Values Endorsement, Compulsive Buying-Shopping Disorder Symptoms and Everyday Moral Decision Making

Author

Müller, Astrid, primary, Georgiadou, Ekaterini, additional, Birlin, Annika, additional, Laskowski, Nora M., additional, Jiménez-Murcia, Susana, additional, Fernández-Aranda, Fernando, additional, Hillemacher, Thomas, additional, de Zwaan, Martina, additional, Brand, Matthias, additional, and Steins-Loeber, Sabine, additional

Published
2022
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217. Emotion regulation as a transdiagnostic factor in eating disorders and gambling disorder: Treatment outcome implications

Author

Vintró-Alcaraz, Cristina, primary, Munguía, Lucero, additional, Granero, Roser, additional, Gaspar-Pérez, Anahi, additional, Solé-Morata, Neus, additional, Sánchez, Isabel, additional, Sánchez-González, Jéssica, additional, Menchón, José M., additional, Jiménez-Murcia, Susana, additional, and Fernández-Aranda, Fernando, additional

Published
2022
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218. Phenotype of Gambling Disorder Patients with Lotteries as a Preferred Form of Gambling

Author

Granero, Roser, primary, Fernández-Aranda, Fernando, additional, Mena-Moreno, Teresa, additional, del Pino-Gutierrez, Amparo, additional, Codina, Ester, additional, Gómez-Peña, Mónica, additional, Moragas, Laura, additional, Aymamí, Neus, additional, Mestre-Bach, Gemma, additional, Steward, Trevor, additional, Agüera, Zaida, additional, Hakånsson, Anders, additional, Vintró-Alcaraz, Cristina, additional, Lozano-Madrid, María, additional, Casalé-Salayet, Gemma, additional, López-González, Hibai, additional, Valenciano-Mendoza, Eduardo, additional, Mora-Maltas, Bernat, additional, Rivas-Pérez, Sandra, additional, Menchón, José M., additional, and Jiménez-Murcia, Susana, additional

Published
2022
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220. Food addiction in anorexia nervosa: Implications for the understanding of crossover diagnosis

Author

Sanchez, Isabel, primary, Lucas, Ignacio, additional, Munguía, Lucero, additional, Camacho‐Barcia, Lucia, additional, Giménez, Mónica, additional, Sánchez‐González, Jessica, additional, Granero, Roser, additional, Solé‐Morata, Neus, additional, Gearhardt, Ashley N., additional, Diéguez, Carlos, additional, Jiménez‐Murcia, Susana, additional, and Fernández‐Aranda, Fernando, additional

Published
2022
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223. Do emotion regulation and impulsivity differ according to gambling preferences in clinical samples of gamblers?

Author

Vintró Alcaraz, Cristina, Mestre-Bach, Gemma, Granero, Roser, Gomez-Peña, Mónica, Moragas, Laura, Fernández-Aranda, Fernando, Jiménez-Murcia, Susana, and Instituto de Salud Carlos III. Ciber Fisiopatología Obesidad y Nutrición (CIBERObn)

Subjects
Impulsivity, SEEKING, Emotions, Medicine (miscellaneous), Gambling disorder, Toxicology, VALIDATION, Non-strategic, medicine, Humans, In patient, UPPS-P, Strategic, POPULATION, Emotion regulation, PATHOLOGICAL GAMBLERS, Behavior disorders, Emocions, Joc compulsiu, PROFILES, ASSOCIATION, Gambling preferences, ALEXITHYMIA, Emotional Regulation, Diagnostic and Statistical Manual of Mental Disorders, Psychiatry and Mental health, Clinical Psychology, BEHAVIOR SCALE, Gambling, Impulsive Behavior, Impulse, Impulsos (Psicologia), Female, medicine.symptom, Psychology, Compulsive gambling, Trastorns de la conducta, COGNITIVE DISTORTIONS, Clinical psychology
Abstract

Background and aims Emotion regulation (ER) and impulsivity impairments have been reported in patients with gambling disorder (GD). However, both constructs have not been studied in depth jointly in clinical samples. Therefore, the aim of this study was to analyze ER and impulsive tendencies/traits in a sample of n = 321 treatment-seeking individuals with GD by differentiating them according to their gambling preference (n = 100 strategic; n = 221 non-strategic). Methods Our sample was assessed through the DERS (ER), the UPPS-P (impulsivity), and the DSM-5 (GD severity). Results The non-strategic group included a higher proportion of women and reported greater ER impairments, and more impulsive traits/tendencies compared to strategic gamblers. GD severity was associated with all DERS subscale (except for awareness) and with urgency dimensions of the UPPS-P. Discussion and conclusions Our findings confirm that strategic and non-strategic gamblers differ in their ER processes and impulsive tendencies, showing the first clinical group a more adaptive profile. These results suggest the relevance of assessing these ER and impulsivity in order to tailor better treatment approaches.

Published
2022

224. Additional file 1 of Impulsivity is longitudinally associated with healthy and unhealthy dietary patterns in individuals with overweight or obesity and metabolic syndrome within the framework of the PREDIMED-Plus trial

Author

Gómez-Martínez, Carlos, Babio, Nancy, Júlvez, Jordi, Nishi, Stephanie K., Fernández-Aranda, Fernando, Martínez-González, Miguel Ángel, Cuenca-Royo, Aida, Fernández, Rebeca, Jiménez-Murcia, Susana, de la Torre, Rafael, Pintó, Xavier, Bloemendaal, Mirjam, Fitó, Montse, Corella, Dolores, Arias, Alejandro, and Salas-Salvadó, Jordi

Abstract

Additional file 1: Supplemental Table 1. Western diet score. Supplemental Table 2. Longitudinal associations between impulsivity and dietary pattern scores by intervention group (n=438).

Published
2022
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225. Impact of COVID-19 Lockdown in Eating Disorders: A Multicentre Collaborative International Study

Author

Baenas, Isabel, Etxandi, Mikel, Munguía, Lucero, Granero, Roser, Mestre-Bach, Gemma, Sánchez, Isabel, Ortega, Emilio, Andreu, Alba, Moize, Violeta L, Fernández-Real, Jose-Manuel, Tinahones, Francisco J, Diéguez, Carlos, Frühbeck, Gema, Le Grange, Daniel, Tchanturia, Kate, Karwautz, Andreas, Zeiler, Michael, Imgart, Hartmut, Zanko, Annika, Favaro, Angela, Claes, Laurence, Shekriladze, Ia, Serrano-Troncoso, Eduardo, Cecilia-Costa, Raquel, Rangil, Teresa, Loran-Meler, Maria Eulalia, Soriano-Pacheco, José, Carceller-Sindreu, Mar, Navarrete, Rosa, Lozano, Meritxell, Linares, Raquel, Gudiol, Carlota, Carratala, Jordi, Plana, Maria T, Graell, Montserrat, González-Parra, David, Gómez-Del Barrio, José A, Sepúlveda, Ana R, Sánchez-González, Jéssica, Machado, Paulo PP, Håkansson, Anders, Túry, Ferenc, Pászthy, Bea, Stein, Daniel, Papezová, Hana, Gricova, Jana, Bax, Brigita, Borisenkov, Mikhail F, Popov, Sergey V, Gubin, Denis G, Petrov, Ivan M, Isakova, Dilara, Mustafina, Svetlana V, Kim, Youl-Ri, Nakazato, Michiko, Godart, Nathalie, van Voren, Robert, Ilnytska, Tetiana, Chen, Jue, Rowlands, Katie, Voderholzer, Ulrich, Monteleone, Alessio M, Treasure, Janet, Jiménez-Murcia, Susana, and Fernández-Aranda, Fernando

Subjects
Adult, Male, Internationality, Asia, Adolescent, Eating Disorders, Feeding and Eating Disorders, Young Adult, Food Sciences, Clinical Research, Behavioral and Social Science, Humans, Longitudinal Studies, Child, Nutrition, Nutrition and Dietetics, SARS-CoV-2, COVID-19 Isolation Eating Scale, Prevention, COVID-19, eating symptoms, Health Services, Brain Disorders, Europe, Mental Health, Good Health and Well Being, Social Isolation, COVID-19 lockdown, Quarantine, Female, psychological impact
Abstract

The COVID-19 lockdown has had a significant impact on mental health. Patients with eating disorders (ED) have been particularly vulnerable. (1) To explore changes in eating-related symptoms and general psychopathology during lockdown in patients with an ED from various European and Asian countries; and (2) to assess differences related to diagnostic ED subtypes, age, and geography. The sample comprised 829 participants, diagnosed with an ED according to DSM-5 criteria from specialized ED units in Europe and Asia. Participants were assessed using the COVID-19 Isolation Scale (CIES). Patients with binge eating disorder (BED) experienced the highest impact on weight and ED symptoms in comparison with other ED subtypes during lockdown, whereas individuals with other specified feeding and eating disorders (OFSED) had greater deterioration in general psychological functioning than subjects with other ED subtypes. Finally, Asian and younger individuals appeared to be more resilient. The psychopathological changes in ED patients during the COVID-19 lockdown varied by cultural context and individual variation in age and ED diagnosis. Clinical services may need to target preventive measures and adapt therapeutic approaches for the most vulnerable patients.

Published
2021

226. Is Pathological Gambling Moderated by Age?

Author

Granero, Roser, Penelo, Eva, Stinchfield, Randy, Fernandez-Aranda, Fernando, Savvidou, Lamprini G., Fröberg, Frida, Aymamí, Neus, Gómez-Peña, Mónica, Pérez-Serrano, Miriam, del Pino-Gutiérrez, Amparo, Menchón, José M., and Jiménez-Murcia, Susana

Published
2014
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227. COVID-19, Health Habits, and Addictive Behaviors in the General Population.

Author

Granero, Roser, Baenas, Isabel, Fernández-Aranda, Fernando, Duran, Joan, Lanuza-Masdeu, Jordi, Mayordomo, Cristina, Potenza, Marc N., Quintana, Almudena, Leyva, Celia, Rodríguez-Ruiz, Francesc, Menchón, José M., and Jiménez-Murcia, Susana

Subjects
COMPULSIVE behavior, COVID-19, MENTAL illness, PSYCHOTHERAPY, FAMILY conflict, HEALTH behavior
Abstract

The lockdown due to the coronavirus disease 2019 (COVID-19) pandemic had a significant impact on daily routines and habits. New lifestyle behaviors contributed to the onset and course of mental diseases, including addictive problems. The objective of this work was to describe changes in health status during lockdown in the general population, including potentially addictive behaviors, and explore possible contributing factors. The analyzed data comprised a population-based sample of 240 individuals (73.3% women, mean age 43.8 years old). Assessments included sociodemographics and self-reports for health state and addictive behaviors. The risk of perceived worsening physical and psychological state was 21.7% and 20.0%, respectively, after the lockdown. The risk of requiring a new treatment for physical and psychological illnesses was 10.4% and 4.2%, respectively, while 2.5% of the participants started using illegal drugs and 9% initiated video game use. Finally, the statistical predictors of health worsening during the lockdown were the presence of anxiety symptoms, being unmarried, having low education levels, experiencing fears related to COVID-19 infection, and having family conflicts. This research identified vulnerability factors contributing to changes in physic and mental health, as well as those associated with addictive behaviors during lockdown. These results should be considered in further stressful situations to design personalized preventive and therapeutic plans. [ABSTRACT FROM AUTHOR]

Published
2023
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231. Eating disorder in gambling disorder: a group with increased psychopathology

Author

Lemón, Linda, Fernández Aranda, Fernando, Jiménez-Murcia, Susana, and Håkansson, Anders

Subjects
Epidemiology, Gambling, Eating disorders, Jocs d'atzar, Epidemiologia, Trastorns de la conducta alimentària
Abstract

Background and aims: theoretical background and previous data provide some similarities between problematic gambling and eating behaviors, and a theoretically increased clinical severity in individuals suffering from both conditions. However, large datasets are lacking, and therefore, the present study aimed to study, in a nationwide register material, psychiatric comorbidity, age and gender in gambling disorder (GD) patients with or without eating disorder (ED). Methods: diagnostic data from a nationwide register were used, including all individuals with a GD diagnosis in specialized health care in Sweden, in the years 2005-2016 (N = 2,099). Patients with GD and an ED diagnosis (n = 57) were compared to GD patients without ED. Results: patients with GD+ED were significantly more likely than other GD patients to also have a diagnosis of drug use disorder, depressive disorders, bipolar disorders, other mood disorder, anxiety disorders, personality disorders, and neuropsychiatric disorders, when controlling for gender. In logistic regression, a comorbid ED in GD was associated with female gender, younger age, depressive disorder and personality disorders. Discussion and conclusion: in nationwide register data, despite the low number of GD+ED patients, GD patients with ED appear to have a more severe psychiatric comorbidity than GD patients without ED. The combined GD+ED conditions may require particular screening and clinical attention, as well as further research in larger and longitudinal studies.

Published
2021

232. Internet gaming disorder clustering based on personality traits in adolescents, and Its relation with comorbid psychological symptoms

Author

González Bueso, Vega, Santamaría, Juan José, Oliveres, Ignasi, Fernández Martínez, Daniel|||0000-0003-0012-2094, Montero, Elena, Baño, Marta, Jiménez Murcia, Susana, del Pino Gutiérrez, Amparo, Ribas, Joan, Universitat Politècnica de Catalunya. Departament d'Estadística i Investigació Operativa, and Universitat Politècnica de Catalunya. GRBIO - Grup de Recerca en Bioestadística i Bioinformàtica

Subjects
Internet gaming disorder, Video game, Cluster analysis, Matemàtiques i estadística::Estadística aplicada::Estadística biosanitària [Àrees temàtiques de la UPC], Ciències de la salut::Salut mental [Àrees temàtiques de la UPC], Internet addicts, Addictes a Internet, Comorbidity, Enginyeria de la telecomunicació::Telemàtica i xarxes d'ordinadors::Internet [Àrees temàtiques de la UPC], Video game addiction, Personality, Anàlisi de conglomerats
Abstract

In recent years, the evidence regarding Internet Gaming Disorder (IGD) suggests that some personality traits are important risk factors for developing this problem. The heterogeneity involved in problematic online gaming and differences found in the literature regarding the comorbid psychopathology associated with the problem could be explained through different types of gamers. Clustering analysis can allow organization of a collection of personality traits into clusters based on similarity. The objectives of this study were: (1) to obtain an empirical classification of IGD patients according to personality variables and (2) to describe the resultant groups in terms of clinical and sociodemographic variables. The sample included 66 IGD adolescent patients who were consecutive referrals at a mental health center in Barcelona, Spain. A Gaussian mixture model cluster analysis was used in order to classify the subjects based on their personality. Two clusters based on personality traits were detected: type I “higher comorbid symptoms” (n = 24), and type II “lower comorbid symptoms” (n = 42). The type I included higher scores in introversive, inhibited, doleful, unruly, forceful, oppositional, self-demeaning and borderline tendency traits, and lower scores in histrionic, egotistic and conforming traits. The type I obtained higher scores on all the Symptom Check List-90 items-Revised, all the State-Trait Anxiety Index scales, and on the DSM-5 IGD criteria. Differences in personality can be useful in determining clusters with different types of dysfunctionality

Published
2021

233. Impact of COVID-19 Lockdown in Eating Disorders: A Multicentre Collaborative International Study

Author

Baenas, Isabel, primary, Etxandi, Mikel, additional, Munguía, Lucero, additional, Granero, Roser, additional, Mestre-Bach, Gemma, additional, Sánchez, Isabel, additional, Ortega, Emilio, additional, Andreu, Alba, additional, Moize, Violeta L., additional, Fernández-Real, Jose-Manuel, additional, Tinahones, Francisco J., additional, Diéguez, Carlos, additional, Frühbeck, Gema, additional, Le Grange, Daniel, additional, Tchanturia, Kate, additional, Karwautz, Andreas, additional, Zeiler, Michael, additional, Imgart, Hartmut, additional, Zanko, Annika, additional, Favaro, Angela, additional, Claes, Laurence, additional, Shekriladze, Ia, additional, Serrano-Troncoso, Eduardo, additional, Cecilia-Costa, Raquel, additional, Rangil, Teresa, additional, Loran-Meler, Maria Eulalia, additional, Soriano-Pacheco, José, additional, Carceller-Sindreu, Mar, additional, Navarrete, Rosa, additional, Lozano, Meritxell, additional, Linares, Raquel, additional, Gudiol, Carlota, additional, Carratala, Jordi, additional, Plana, Maria T., additional, Graell, Montserrat, additional, González-Parra, David, additional, Gómez-del Barrio, José A., additional, Sepúlveda, Ana R., additional, Sánchez-González, Jéssica, additional, Machado, Paulo P. P., additional, Håkansson, Anders, additional, Túry, Ferenc, additional, Pászthy, Bea, additional, Stein, Daniel, additional, Papezová, Hana, additional, Gricova, Jana, additional, Bax, Brigita, additional, Borisenkov, Mikhail F., additional, Popov, Sergey V., additional, Gubin, Denis G., additional, Petrov, Ivan M., additional, Isakova, Dilara, additional, Mustafina, Svetlana V., additional, Kim, Youl-Ri, additional, Nakazato, Michiko, additional, Godart, Nathalie, additional, van Voren, Robert, additional, Ilnytska, Tetiana, additional, Chen, Jue, additional, Rowlands, Katie, additional, Voderholzer, Ulrich, additional, Monteleone, Alessio M., additional, Treasure, Janet, additional, Jiménez-Murcia, Susana, additional, and Fernández-Aranda, Fernando, additional

Published
2021
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234. Clustering Treatment Outcomes in Women with Gambling Disorder

Author

Lara-Huallipe, Milagros Lizbeth, primary, Granero, Roser, additional, Fernández-Aranda, Fernando, additional, Gómez-Peña, Mónica, additional, Moragas, Laura, additional, del Pino-Gutierrez, Amparo, additional, Valenciano-Mendoza, Eduardo, additional, Mora-Maltas, Bernat, additional, Baenas, Isabel, additional, Etxandi, Mikel, additional, Menchón, José M., additional, and Jiménez-Murcia, Susana, additional

Published
2021
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235. Does Confinement Affect Treatment Dropout Rates in Patients With Gambling Disorder? A Nine-Month Observational Study

Author

Baenas, Isabel, primary, Etxandi, Mikel, additional, Codina, Ester, additional, Granero, Roser, additional, Fernández-Aranda, Fernando, additional, Gómez-Peña, Mónica, additional, Moragas, Laura, additional, Rivas, Sandra, additional, Potenza, Marc N., additional, Håkansson, Anders, additional, del Pino-Gutiérrez, Amparo, additional, Mora-Maltas, Bernat, additional, Valenciano-Mendoza, Eduardo, additional, Menchón, José M., additional, and Jiménez-Murcia, Susana, additional

Published
2021
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236. Transdiagnostic Perspective of Impulsivity and Compulsivity in Obesity: From Cognitive Profile to Self-Reported Dimensions in Clinical Samples with and without Diabetes

Author

Testa, Giulia, primary, Mora-Maltas, Bernat, additional, Camacho-Barcia, Lucía, additional, Granero, Roser, additional, Lucas, Ignacio, additional, Agüera, Zaida, additional, Jiménez-Murcia, Susana, additional, Baños, Rosa, additional, Bertaina-Anglade, Valerie, additional, Botella, Cristina, additional, Bulló, Mònica, additional, Casanueva, Felipe F., additional, Dalsgaard, Søren, additional, Fernández-Real, José-Manuel, additional, Franke, Barbara, additional, Frühbeck, Gema, additional, Fitó, Montserrat, additional, Gómez-Martínez, Carlos, additional, Pintó, Xavier, additional, Poelmans, Geert, additional, Tinahones, Francisco J., additional, de la Torre, Rafael, additional, Salas-Salvadó, Jordi, additional, Serra-Majem, Lluis, additional, Vos, Stephanie, additional, Wimberley, Theresa, additional, and Fernández-Aranda, Fernando, additional

Published
2021
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237. Psychological and Personality Predictors of Weight Loss and Comorbid Metabolic Changes After Bariatric Surgery

Author

Agüera, Zaida, García-Ruiz-de-Gordejuela, Amador, Vilarrasa, Nuria, Sanchez, Isabel, Baño, Marta, Camacho, Lucía, Granero, Roser, Jiménez-Murcia, Susana, Virgili, Nuria, Lopez-Urdiales, Rafael, de Bernabe, Mónica Montserrat-Gil, Garrido, Pilar, Monasterio, Carmen, Steward, Trevor, Pujol-Gebelli, Jordi, Fernández-Aranda, Fernando, and Menchón, Jose M.

Published
2015
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238. Circulating Betatrophin Levels Are Increased in Anorexia and Decreased in Morbidly Obese Women

Author

Barja-Fernández, Silvia, Folgueira, Cintia, Seoane, Luisa M., Casanueva, Felipe F., Dieguez, Carlos, Castelao, Cecilia, Agüera, Zaida, Baños, Rosa, Botella, Cristina, de la Torre, Rafael, Fernández-García, Jose C., Fernández-Real, Jose M., Frühbeck, Gema, Gómez-Ambrosi, Javier, Jiménez-Murcia, Susana, Tinahones, Francisco J., Estivill, Xavier, Fernández-Aranda, Fernando, and Nogueiras, Ruben

Published
2015

243. Gambling addiction:: Myth or reality? Analysing the scientific evidence on gambling disorder

Author

Mestre Bach, Gemma, Valenciano Mendoza, Eduardo, Mora Maltas, Bernat, Fernández Aranda, Fernando, and Jiménez Murcia, Susana

Subjects
Evidence-based medicine, Medicina basada en l'evidència, Joc compulsiu, Compulsive gambling
Abstract

Interest in gambling disorder, formerly known as pathological gambling, has been growing in both the clinical and scientific community. The increase in empirical evidence concerning gambling disorder has permitted a better understanding of the pathology, as well as the identification of common comorbidities and the design of potential therapeutic options. The present review addresses all these issues, including recent findings in this area of study.

Published
2021

244. Clustering Treatment Outcomes in Women with Gambling Disorder.

Author

Lara-Huallipe, Milagros Lizbeth, Granero, Roser, Fernández-Aranda, Fernando, Gómez-Peña, Mónica, Moragas, Laura, del Pino-Gutierrez, Amparo, Valenciano-Mendoza, Eduardo, Mora-Maltas, Bernat, Baenas, Isabel, Etxandi, Mikel, Menchón, José M., and Jiménez-Murcia, Susana

Subjects
TREATMENT effectiveness, COGNITIVE therapy, SELF-esteem, COMPULSIVE gambling, PERSONALITY, EMOTION regulation, SOCIAL status
Abstract

The rising prevalence of gambling disorder (GD) among women has awakened considerable interest in the study of therapeutic outcomes in females. This study aimed to explore profiles of women seeking treatment for GD based on a set of indicators including sociodemographic features, personality traits, clinical state at baseline, and cognitive behavioral therapy (CBT) outcomes. Two-step clustering, an agglomerative hierarchical classification system, was applied to a sample of n = 163 women of ages ranging from 20 to 73 years-old, consecutively attended to by a clinical unit specialized in the treatment of G. Three mutually exclusive clusters were identified. Cluster C1 (n = 67, 41.1%) included the highest proportion of married, occupationally active patients within the highest social status index. This cluster was characterized by medium GD severity levels, the best psychopathological functioning, and the highest mean in the self-directedness trait. C1 registered 0% dropouts and only 14.9% relapse. Cluster C2 (n = 63; 38.7%) was characterized by the lowest GD severity, medium scores for psychopathological measures and a high risk of dropout during CBT. Cluster C3 (n = 33; 20.2%) registered the highest GD severity, the worst psychopathological state, the lowest self-directedness level and the highest harm-avoidance level, as well as the highest risk of relapse. These results provide new evidence regarding the heterogeneity of women diagnosed with GD and treated with CBT, based on the profile at pre- and post-treatment. Person-centered treatments should include specific strategies aimed at increasing self-esteem, emotional regulation capacities and self-control of GD women. [ABSTRACT FROM AUTHOR]

Published
2022
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245. Identifying Associated Factors for Illegal Acts among Patients with Gambling Disorder and ADHD.

Author

Vintró-Alcaraz, Cristina, Mestre-Bach, Gemma, Granero, Roser, Cuquerella, Àngel, Talón-Navarro, María-Teresa, Valenciano-Mendoza, Eduardo, Mora-Maltas, Bernat, del Pino-Gutiérrez, Amparo, Gómez-Peña, Mónica, Moragas, Laura, Fernández-Aranda, Fernando, Codina, Ester, Valero-Solís, Susana, Guillén-Guzmán, Elías, Lara-Huallipe, Milagros Lizbeth, Solé-Morata, Neus, and Jiménez-Murcia, Susana

Subjects
CRIMINAL behavior, COMPULSIVE gambling, ATTENTION-deficit hyperactivity disorder, PERSONALITY, STRUCTURAL equation modeling
Abstract

Illegal behaviors have been reported in gambling disorder (GD) as well as in individuals with attention deficit hyperactivity disorder (ADHD). Likewise, ADHD symptomatology has been observed in patients with GD. We aimed to examine the association between ADHD symptomatology, personality traits and impulsivity in a sample of treatment-seeking patients with GD (n = 204) with and without a criminal report. The subjects were evaluated before starting treatment using different self-administered instruments. Among those who had committed an illegal act, two groups were made depending on whether or not the criminal conduct had legal repercussions (n = 64 without legal consequences; n = 32 with legal consequences). Structural equation modeling (SEM) was used to explore the interrelationships between personality traits, ADHD, impulsivity levels, gambling-related criminal behavior and other gambling-related factors. Greater ADHD symptomatology was found in patients with reported illegal behaviors, as well as higher impulsivity levels. Those individuals who presented legal consequences due to the criminal behavior showed higher impulsivity levels and harm avoidance and lower persistence and cooperativeness. Our findings uphold that patients with GD and ADHD symptomatology have greater impulsivity and are more vulnerable to committing an illegal act. Therefore, specific harm-prevention interventions and treatment approaches are needed for this population. [ABSTRACT FROM AUTHOR]

Published
2022
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246. The role of neurotrophin genes involved in the vulnerability to gambling disorder.

Author

Solé-Morata, Neus, Baenas, Isabel, Etxandi, Mikel, Granero, Roser, Forcales, Sonia V., Gené, Manel, Barrot, Carme, Gómez-Peña, Mónica, Menchón, José M., Ramoz, Nicolás, Gorwood, Philip, Fernández-Aranda, Fernando, and Jiménez-Murcia, Susana

Subjects
COMPULSIVE gambling, SINGLE nucleotide polymorphisms, LINKAGE disequilibrium, GENETIC polymorphisms, HAPLOTYPES, NEUROTROPHIN receptors
Abstract

Evidence about the involvement of genetic factors in the development of gambling disorder (GD) has been assessed. Among studies assessing heritability and biological vulnerability for GD, neurotrophin (NTF) genes have emerged as promising targets, since a growing literature showed a possible link between NTF and addiction-related disorders. Thus, we aimed to explore the role of NTF genes and GD with the hypothesis that some NTF gene polymorphisms could constitute biological risk factors. The sample included 166 patients with GD and 191 healthy controls. 36 single nucleotide polymorphisms (SNPs) from NTFs (NGF, NGFR, NTRK1, BDNF, NTRK2, NTF3, NTRK3, NTF4, CNTF and CNTFR) were selected and genotyped. Linkage disequilibrium (LD) and haplotype constructions were analyzed, in relationship with the presence of GD. Finally, regulatory elements overlapping the identified SNPs variants associated with GD were searched. The between groups comparisons of allele frequencies indicated that 6 SNPs were potentially associated with GD. Single and multiple-marker analyses showed a strong association between both NTF3 and NTRK2 genes, and GD. The present study supports the involvement of the NTF family in the aetiopathogenesis of GD. An altered cross-regulation of different NTF members signalling pathways might be considered as a biological vulnerability factor for GD. [ABSTRACT FROM AUTHOR]

Published
2022
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249. Identifying Associated Factors for Illegal Acts among Patients with Gambling Disorder and ADHD

Author

Vintró-Alcaraz, Cristina, primary, Mestre-Bach, Gemma, additional, Granero, Roser, additional, Cuquerella, Àngel, additional, Talón-Navarro, María-Teresa, additional, Valenciano-Mendoza, Eduardo, additional, Mora-Maltas, Bernat, additional, del Pino-Gutiérrez, Amparo, additional, Gómez-Peña, Mónica, additional, Moragas, Laura, additional, Fernández-Aranda, Fernando, additional, Codina, Ester, additional, Valero-Solís, Susana, additional, Guillén-Guzmán, Elías, additional, Lara-Huallipe, Milagros Lizbeth, additional, Solé-Morata, Neus, additional, and Jiménez-Murcia, Susana, additional

Published
2021
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