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1,271 results on '"Khan, Sardar"'

201. Su1265: IMPACT OF PRE-EXISTING AND NEW-ONSET DIABETES ON SURVIVAL AMONG PATIENTS WITH PANCREATIC CANCER: ANALYSIS OF A LARGE MULTI-INSTITUTIONAL RESEARCH NETWORK STUDY

Author

Hadi, Yousaf, primary, Singh, Shailendra, additional, Shah-Khan, Sardar M., additional, Syed, Aslam, additional, Humphries, Christine E., additional, Daum, Tracy L., additional, Sohail, Amir H. Humza, additional, Jannat, FNU Rida Ul, additional, Khan, Ahmad, additional, Krafft, Matthew R., additional, Bilal, Mohammad, additional, and Thakkar, Shyam, additional

Published
2022
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204. 685: RISK OF PANCREATIC CANCER IN PATIENTS TREATED WITH GLUCAGON LIKE PEPTIDE-1 (GLP-1) RECEPTOR AGONISTS: A LARGE MULTI-CENTER COHORT STUDY

Author

Singh, Shailendra, primary, Shah-Khan, Sardar M., additional, Hadi, Yousaf, additional, Khan, Ahmad, additional, Sohail, Amir H., additional, Daum, Tracy L., additional, Humphries, Christine E., additional, Chowdhry, Monica, additional, Malik, Adnan, additional, Sohail, Abdullah, additional, Jannat, FNU Rida Ul, additional, Bilal, Mohammad, additional, Hutson, William R., additional, and Thakkar, Shyam, additional

Published
2022
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208. Community succession and drivers of CO2-fixing microbes in recently deglaciated soils on the Tibetan Plateau.

Author

Khan, Ajmal, Kong, Weidong, Khan, Sardar, and Nawab, Javed

Subjects
COMMUNITIES, SOILS, PLATEAUS, COLONIZATION (Ecology), SOIL formation, GLACIAL melting, AUTOTROPHIC bacteria
Abstract

Purpose: Proglacial terrains provide an ideal environment to determine soil formation and microbial colonization, where autotrophic microbes could play a role as primary producers. We investigated the succession and drivers of autotrophic microorganisms harboring the cbbL gene in deglaciated soils across a 14-year deglaciation chronosequence on the Tibetan Plateau. Materials and methods: Surface soils were collected in triplicate at 15 points beginning at the glacier terminus. The abundance and community composition of autotrophic microbes were determined using quantitative PCR and sequencing of clone libraries, respectively. Results and discussion: The abundance of form IC and ID cbbL increased gradually across deglaciation chronosequence, while form IA/B cbbL increased during the first 5 years since deglaciation and then remained stable. The succession of form IA/B and ID autotrophs occurred in a similar manner over three deglaciation stages, early (0-year-old), transitional (1–7-year-old), and late stage (8–14-year-old), whereas form IC autotrophs displayed distinct succession in the early (0–3-year-old) and transitional stage (4–7-year-old). Autotrophic microbial succession was prominently driven by soil moisture, pH, total carbon, and deglaciation age. Proteobacteria dominated young deglaciated soils (4–5-year-old), while Stramenopiles dominated old deglaciated soils (13-year-old). These findings revealed that autotrophic microbes follow clear successional patterns across recently deglaciated chronosequences and are primarily influenced by physicochemical parameters. Conclusions: Autotrophic microbes quickly colonized deglaciated soils following glacier retreat, and their population increased with increasing deglaciation age. Physicochemical parameters played an important role in driving autotrophic microbes in the early, transitional, and late stages. Chemoautotrophic Proteobacterial-dominated young deglaciated soils to photoautotrophic algae-dominated old deglaciated soils. [ABSTRACT FROM AUTHOR]

Published
2023
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209. Clinical utility of ozone therapy and hyperbaric oxygen therapy in degenerative disc disease.

Author

Re, Kaitlyn, Gandhi, Jason, Liang, Raymond, Patel, Shrey, Joshi, Gunjan, Smith, Noel, Reid, Inefta, and Khan, Sardar Ali

Subjects
HYPERBARIC oxygenation, OZONE therapy, DEGENERATION (Pathology), WOUND healing, OZONE, INTERVERTEBRAL disk hernias
Abstract

Ozone can be medically useful concerning healing wounds and relieving pain in various conditions, such as disc disease. The aspects of human blood ozonation have been reviewed, as well as potential complications that may arise. The mechanisms of ozone therapy are discussed in detail. It is imperative to recognize ozone as a useful proxy in oxidative-stress related diseases, consolidating other medical gases recognized for their therapeutic importance. The utility of hyperbaric oxygen therapy is also discussed. Disc herniation is very common, as more than 3 million cases are treated per year. Herein we review the medical, surgical, and gene-based therapies that ozone therapy can provide regarding disc disease. [ABSTRACT FROM AUTHOR]

Published
2023
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212. Hydrogeochemical modeling evaluating carcinogenic and noncarcinogenic health risk of potentially toxic elements, integrating groundwater pollution indexing: Insights of GIS-based and geostatistical approaches

Author

Rashid, Abdur, primary, Ayub, Muhammad, additional, Khan, Sardar, additional, Ullah, Zahid, additional, Ali, Liaqat, additional, Gao, Xubo, additional, Li, Chengcheng, additional, El-Serehy, Hamed A., additional, Kaushik, Prashant, additional, and Rasool, Atta, additional

Published
2022
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223. Whole Exome Sequencing Confirms Molecular Diagnostics of Three Pakhtun Families With Autosomal Recessive Epidermolysis Bullosa

Author

Fozia, Fozia, Nazli, Rubina, Bibi, Nousheen, Khan, Sardar Sher Alam, Muhammad, Noor, Shakeeb, Nafila, Khan, M. Zakir Saadullah, Jelani, Musharraf, and Wasif, Naveed

Subjects
Exome sequence, Autosomal recessive, Pediatrics, Perinatology and Child Health, PLEC gene, Epidermolysis bullosa, Genetics, COL17A1 gene, Exome, ddc:610, DDC 610 / Medicine & health
Abstract

Epidermolysis bullosa (EB) is a genetic skin disorder that shows heterogeneous clinical fragility. The patients develop skin blisters congenitally or in the early years of life at the dermo-epithelial junctions, including erosions, hyperkeratosis over the palms and soles. The other associated features are hypotrichosis on the scalp, absent or dystrophic nails, and dental anomalies. Molecular diagnosis through whole-exome sequencing (WES) has become one of the successful tool in clinical setups. In this study, three Pakhtun families from the Khyber Pakhtunkhwa province of Pakistan were ascertained. WES analysis of a proband in each family revealed two novel variants (COL17A1: NM_000494.4: c.4041T>G: p.Y1347 and PLEC: NM_201380.3: c.1283_1285delGCT: p.L426del) and one previously known COL17A1: NM_000494.4:c.3067C>T: p.Q1023 ) variant in homozygous forms. Sanger sequencing of the identified variants confirmed that the heterozygous genotypes of the obligate carriers. The identified variants have not only increased the mutation spectrum of the COL17A1 and PLEC but also confirms their vital role in the morphogenesis of skin and its associated appendages. WES can be used as a first-line diagnostic tool in genetic testing and counselling families from Khyber Pakhtunkhwa, Pakistan., publishedVersion

Published
2021
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225. Acute fatty liver of pregnancy masquerading as diabetic ketoacidosis

Author

Muhammad Shoaib Khan Sardar, Athar Iqbal Khan Muhammad, Mehreen Anwar, and Yamin thant

Subjects
medicine.medical_specialty, Diabetic ketoacidosis, business.industry, Internal medicine, medicine, medicine.disease, business, Gastroenterology, Acute fatty liver of pregnancy
Published
2021

227. Grave’s disease in a patient with thyroid hemiagenesis

Author

Niels Larsen, Muhammad Shoaib Khan Sardar, Pang Eleanor Jane, and Aifa Aboobakuru Aminath

Subjects
Pediatrics, medicine.medical_specialty, business.industry, Graves' disease, medicine, Thyroid hemiagenesis, medicine.disease, business
Published
2021

239. Adsorption of Pesticides Using Wood-Derived Biochar and Granular Activated Carbon in a Fixed-Bed Column System.

Author

Kalsoom, Khan, Sardar, Ullah, Rafi, Adil, Muhammad, Waheed, Abdul, Khan, Khalid Ali, Ghramh, Hamed A., Alharby, Hesham F., Alzahrani, Yahya M., Alghamdi, Sameera A., Alabdallah, Nadiyah M., and Rahim, Fazli

Subjects
ACTIVATED carbon, COLUMNS, PESTICIDES, BIOCHAR, ADSORPTION (Chemistry), ATRAZINE
Abstract

Pesticides have great potential to contaminate resources of drinking water by percolating and leaching, when applied in the agriculture sector as well as in domestic region. Activated carbon (AC) and Biochar (BCH) were used for adsorption in a fixed-bed column system. Both of the adsorbent-packed columns indicated an increase in the breakthrough time for atrazine from 3350 to 5800 min and 3200 to 5700 min, chlorothalanil 3200–5600 min and 3150–5550 min, β-endosulfan 3050–5400 min and 2950–5400 min, and α-endosulfan 2900–5200 min and 2850–5200 min with bed heights from 10 cm to 15 cm, respectively. Similarly, when flow rate increased from 0.5 to 1.5 mL min−1 and contaminant concentration from 50–100 µg L−1, it resulted in a decrease in exhaust time. The models of Yoon–Nelson (R2 = 0.9427) and Thomas (R2 = 0.9921) describe the process of adsorption to be best well-under optimal conditions. Both the adsorbents would be efficiently utilized as the best adsorbents to remediate pesticide-contaminated water under optimal conditions. Pesticides adsorption onto adsorbents followed the order of atrazine > chlorothalanil > β-endosulfan > α-endosulfan. [ABSTRACT FROM AUTHOR]

Published
2022
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242. Inventorization of traditional ethnobotanical uses of wild plants of Dawarian and Ratti Gali areas of District Neelum, Azad Jammu and Kashmir Pakistan

Author

Ajaib, Muhammad, primary, Ishtiaq, Muhammad, additional, Bhatti, Khizar Hayat, additional, Hussain, Iqbal, additional, Maqbool, Mehwish, additional, Hussain, Tanveer, additional, Mushtaq, Waheeda, additional, Ghani, Abdul, additional, Azeem, Muhammad, additional, Khan, Sardar Muhammad Rafique, additional, Thind, Sumaira, additional, and Bashir, Rohina, additional

Published
2021
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244. Contamination Level, Source Identification And Health Risk Assessment of Potentially Toxic Elements In Drinking Water Sources of Mining And Non-Mining Areas of Khyber Pakhtunkhwa, Pakistan

Author

Bhatti, Zahid, primary, Ishtiaq, Muhammad, additional, Khan, Said, additional, nawab, javed, additional, Khan, Sardar, additional, Baig, Shams, additional, Muhammad, Ihsan, additional, Din, Zia, additional, Khan, Asad, additional, and Ghani, Junaid, additional

Published
2021
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246. Contamination Level, Source Identification and Health Risk Assessment of Potentially Toxic Elements in Drinking Water Sources of Mining and Non-mining Areas of Khyber Pakhtunkhwa, Pakistan

Author

Bhatti, Zahid Imran, primary, Ishtiaq, Muhammad, additional, Khan, Said Akbbar, additional, nawab, javed, additional, Khan, Sardar, additional, Baig, Shams Ali, additional, muhammad, Ihsan, additional, Din, Zia ud, additional, Khan, Asad, additional, and Ghani, junaid, additional

Published
2021
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