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1,058 results on '"Kirova, Youlia"'

203. Radioparp: A phase I of olaparib with radiation therapy (RT) in patients with inflammatory, locoregionally advanced or metastatic triple-negative breast cancer (TNBC) or patient with operated TNBC with residual disease—Preliminary results.

Author

Kirova, Youlia M., primary, Loirat, Delphine, additional, Berger, Frederique, additional, Rodrigues, Manuel, additional, Bazire, Louis, additional, Pierga, Jean-Yves, additional, Ricci, Francesco, additional, Cao, Kim, additional, Vincent -Salomon, Anne, additional, Laki, Fatima, additional, Ezzili, Cyrine, additional, Raizonville, Laurence, additional, Mosseri, Veronique, additional, Neffati, Souhir, additional, Ezzalfani, Mounia, additional, and Fourquet, Alain, additional

Published
2020
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206. Radiation therapy to the primary tumor for de novo metastatic breast cancer and overall survival in a retrospective multicenter cohort analysis

Author

Pons-Tostivint, Elvire, primary, Kirova, Youlia, additional, Lusque, Amélie, additional, Campone, Mario, additional, Geffrelot, Julien, additional, Rivera, Sofia, additional, Mailliez, Audrey, additional, Pasquier, David, additional, Madranges, Nicolas, additional, Firmin, Nelly, additional, Crouzet, Agathe, additional, Gonçalves, Anthony, additional, Jankowski, Clémentine, additional, De La Motte Rouge, Thibault, additional, Pouget, Nicolas, additional, De La Lande, Brigitte, additional, Mouttet-Boizat, Delphine, additional, Ferrero, Jean-Marc, additional, Uwer, Lionel, additional, Eymard, Jean-Christophe, additional, Mouret-Reynier, Marie-Ange, additional, Petit, Thierry, additional, Courtinard, Coralie, additional, Filleron, Thomas, additional, Robain, Mathieu, additional, and Dalenc, Florence, additional

Published
2020
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207. Maximizing the Clinical Benefit of Radiotherapy in Solitary Plasmacytoma: An International Multicenter Analysis

Author

Elsayad, Khaled, primary, Oertel, Michael, additional, König, Laila, additional, Hüske, Sebastian, additional, Le Ray, Emmanuelle, additional, Meheissen, Mohamed A.M., additional, Elsaid, Amr Abdelaziz, additional, Elfaham, Essam, additional, Debus, Jürgen, additional, Kirova, Youlia, additional, Herfarth, Klaus, additional, and Eich, Hans Theodor, additional

Published
2020
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210. Abstract P4-12-05: A retrospective study of 27 patients with ER-positive, HER2 negative metastatic breast cancer treated with concomitant palbociclib and radiation therapy

Author

Beddok, Arnaud, primary, Arsene-Henry, Alexandre, additional, Porte, Baptiste, additional, Cao, Kim, additional, Bazire, Louis, additional, Scher, Nathaniel, additional, Labib, Alain, additional, Darmon, Ilan, additional, Otz, Joëlle, additional, Minsat, Mathieu, additional, Mammar, Hamid, additional, Bidar, François Clément, additional, Fourquet, Alain, additional, Cottu, Paul, additional, Poortmans, Phlip, additional, and Kirova, Youlia, additional

Published
2020
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214. Abstract OT2-03-01: A phase one trial of olaparib with radiation therapy in patients with triple negative breast cancer: RADIOPARP

Author

Kirova, Youlia M., primary, Loirat, Delphine, additional, Berger, Frederique, additional, Rodrigues, Manuel, additional, Bazire, Louis, additional, Chilles, Anne, additional, Pierga, Jean Yves, additional, Ricci, Francesco, additional, Sablin, Marie Paule, additional, Salomon, Anne Vincent, additional, Laki, Fatima, additional, Bertrand, Claire, additional, Ezzili, Cyrine, additional, Raizoville, Laurence, additional, Mosseri, Veronique, additional, Neffati, Souhir, additional, Ezzalfani, Monia, additional, and Fourquet, Alain, additional

Published
2020
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225. Hypofractionated whole breast irradiation after conservative surgery for patients aged less than 60 years: a multi-centre comparative study

Author

Icro Meattini, Poortmans, Philip, Kirova, Youlia, Saieva, Calogero, Visani, Luca, Salvestrini, Viola, Jiyoung Kim, Wonguen Jung, Olmetto, Emanuela, Mariotti, Matteo, Desideri, Isacco, Fourquet, Alain, Livi, Lorenzo, and Kyubo Kim

Abstract

Background: For decades, conventional fractionated whole breast irradiation (CF-WBI) was used after breast conserving surgery (BCS). Pivotal phase-3 trials on hypofractionated-WBI (HF-WBI) showed its non-inferiority as compared to CF-WBI. However, younger patients are often not treated with HF-WBI. The aim of this multi-centre comparative study is to confirm the safety of HF-WBI in a real-life series of younger patients. Material and methods: Between 2010 and 2016, a total of 786 patients aged less than 60 years old with early-stage breast cancer were treated with postoperative WBI after BCS in three breast cancer centres: 340 underwent HF-WBI while 446 were treated with CF-WBI. Acute toxicity was evaluated at the end of WBI. Late toxicity was evaluated at 6, 12, 24 and 36 months. Results: At univariate logistic analysis, hypofractionation showed a significant protective effect in terms of acute oedema, acute wet desquamation, chronic oedema, chronic erythema/pigmentation and breast fibrosis. At multivariate logistic analysis, hypofractionation was an independent significant factor for acute oedema, acute wet desquamation, and chronic oedema. There were not differences in tumour-related outcomes. Conclusions: HF-WBI showed significantly improved outcomes in terms of acute skin oedema, wet desquamation and chronic skin oedema. HF-WBI after BCS should be strongly encouraged to replace CF-WBI independently of age.

Published
2019
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226. Decision making factors of the management of ductal carcinoma in situ of the breast with microinvasion

Author

Bouter, Jordan, Geffrelot, Julien, Danhier, Serge, Levy, Christelle, Le Brun, Jean-François, Hanzen, Chantal, Kirova, Youlia, Thariat, Juliette, Institut Curie, Laboratoire de physique corpusculaire de Caen (LPCC), Université de Caen Normandie (UNICAEN), Normandie Université (NU)-Normandie Université (NU)-École Nationale Supérieure d'Ingénieurs de Caen (ENSICAEN), Normandie Université (NU)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Institut Curie [Paris], and Normandie Université (NU)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)

Subjects
[PHYS]Physics [physics]
Abstract

International audience; IntroductionMicroinvasive in situ ductal carcinomas of the breast are rare and of good prognosis. They are grouped with early stage invasive carcinomas in the TNM 2017 classification. This study assessed practitioners’ treatment decisions and their justifications in comparison to the literature.Materials and methodsThree clinical cases were evaluated by anonymous forms regarding sentinel node decisions, tumour bed boost irradiation and hormone therapy.ResultsSentinel lymph node was performed by 93.1%, 100% and 44.4% of the practitioners respectively. Radiation boost was a treatment option chosen by 62.1% and 61.1% of practitioners in both clinical cases. Hormone therapy was advocated for 65.5%, 94.7% and 50.0% patients depending on the clinical case.ConclusionThe therapeutic attitude proposed in microinvasive breast carcinomas was heterogeneous in this study, reflecting the absence of specific recommendations. In view of the existing literature, it is not currently possible to propose recommendations for these three therapeutic options. Prospective cohorts and meta-analyses of the microinvasive subgroup could provide answers.

Published
2019
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229. ESTRO ACROP consensus guideline for target volume delineation in the setting of postmastectomy radiation therapy after implant-based immediate reconstruction for early stage breast cancer.

Author

UCL - SSS/IREC/SLUC - Pôle St.-Luc, UCL - (SLuc) Service de radiothérapie oncologique, Kaidar-Person, Orit, Vrou Offersen, Birgitte, Hol, Sandra, Arenas, Meritxell, Aristei, Cynthia, Bourgier, Celine, Cardoso, Maria Joao, Chua, Boon, Coles, Charlotte E, Engberg Damsgaard, Tine, Gabrys, Dorota, Jagsi, Reshma, Jimenez, Rachel, Kirby, Anna M, Kirkove, Carine, Kirova, Youlia, Kouloulias, Vassilis, Marinko, Tanja, Meattini, Icro, Mjaaland, Ingvil, Nader Marta, Gustavo, Witt Nystrom, Petra, Senkus, Elzbieta, Skyttä, Tanja, Tvedskov, Tove F, Verhoeven, Karolien, Poortmans, Philip, UCL - SSS/IREC/SLUC - Pôle St.-Luc, UCL - (SLuc) Service de radiothérapie oncologique, Kaidar-Person, Orit, Vrou Offersen, Birgitte, Hol, Sandra, Arenas, Meritxell, Aristei, Cynthia, Bourgier, Celine, Cardoso, Maria Joao, Chua, Boon, Coles, Charlotte E, Engberg Damsgaard, Tine, Gabrys, Dorota, Jagsi, Reshma, Jimenez, Rachel, Kirby, Anna M, Kirkove, Carine, Kirova, Youlia, Kouloulias, Vassilis, Marinko, Tanja, Meattini, Icro, Mjaaland, Ingvil, Nader Marta, Gustavo, Witt Nystrom, Petra, Senkus, Elzbieta, Skyttä, Tanja, Tvedskov, Tove F, Verhoeven, Karolien, and Poortmans, Philip

Abstract

Immediate breast reconstruction (IBR) rates after mastectomy are increasing. Postmastectomy radiation therapy (PMRT) contouring guidelines for target volumes in the setting of IBR are lacking. Therefore, many patients who have had IBR receive PMRT to target volumes similar to conventional simulator-based whole breast irradiation. The aim of this paper is to describe delineation guidelines for PMRT after implant-based IBR based on a thorough understanding of the surgical procedures, disease stage, patterns of recurrence and radiation techniques. They are based on a consensus endorsed by a global multidisciplinary group of breast cancer experts.

Published
2019

230. Breast Lipoma

Author

Kirova, Youlia M., Feuilhade, Frank, and Le Bourgeois, Jean-Paul

Published
2002

231. Risk of Lymphedema Following Contemporary Treatment for Breast Cancer An Analysis of 7617 Consecutive Patients From a Multidisciplinary Perspective.

Author

Hwa Kyung Byun, Jee Suk Chang, Sang Hee Im, Kirova, Youlia M., Arsene-Henry, Alexandre, Seo Hee Choi, Young Up Cho, Hyung Seok Park, Jee Ye Kim, Chang-Ok Suh, Ki Chang Keum, Joo Hyuk Sohn, Gun Min Kim, Ik Jae Lee, Jun Won Kim, and Yong Bae Kim

Abstract

Objective: The aim of this study was to identify the comprehensive risk factors for lymphedema, thereby enabling a more informed multidisciplinary treatment decision-making. Summary Background Data: Lymphedema is a serious long-term complication in breast cancer patients post-surgery; however, the influence of multimodal therapy on its occurrence remains unclear. Methods: We retrospectively collected treatment-related data from 5549 breast cancer patients who underwent surgery between 2007 and 2015 at ourinstitution. Individual radiotherapy plans were reviewed for regional nodal irradiation (RNI) field design and fractionation type. We identified lymphedema risk factors and used them to construct nomograms to predict individual risk of lymphedema. Nomograms were validated internally using 100 bootstrap samples and externally using 2 separate datasets of 1877 Asian and 191 Western patients. Results: Six hundred thirty-nine patients developed lymphedema during a median follow-up of 60 months. The 3-year lymphedema incidence was 10.5%; this rate increased with larger irradiation volumes (no RNI vs RNI excluding axilla I– II vs RNI including axilla I– II: 5.7% vs 16.8% vs 24.1%) and when using conventional fractionation instead of hypofractionation (13.5% vs 6.8%). On multivariate analysis, higher body mass index, larger number of dissected nodes, taxane-based regimen, total mastectomy, larger irradiation field, and conventional fractionation were strongly associated with lymphedema (all P < 0.001). Nomograms constructed based on these variables showed good calibration and discrimination internally (concordance index: 0.774) and externally (0.832 for Asian and 0.820 for Western patients). Conclusions: Trimodality breast cancer treatment factors interact to promote lymphedema. Lymphedema risk can be decreased by deintensifying node dissection, chemotherapy regimen, and field and dose of radiotherapy. Deescalation strategies on a multidisciplinary basis might minimize lymphedema risk. [ABSTRACT FROM AUTHOR]

Published
2021
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232. In Reply to Khosla et al

Author

Kirova, Youlia M., primary, Boulle, Geoffroy, additional, De La Lande, Brigitte, additional, and Fourquet, Alain, additional

Published
2019
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234. Hypofractionated whole breast irradiation after conservative surgery for patients aged less than 60 years: a multi-centre comparative study

Author

Meattini, Icro, primary, Poortmans, Philip, additional, Kirova, Youlia, additional, Saieva, Calogero, additional, Visani, Luca, additional, Salvestrini, Viola, additional, Kim, Jiyoung, additional, Jung, Wonguen, additional, Olmetto, Emanuela, additional, Mariotti, Matteo, additional, Desideri, Isacco, additional, Fourquet, Alain, additional, Livi, Lorenzo, additional, and Kim, Kyubo, additional

Published
2019
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235. Breast Implant Associated-Anaplastic Large Cell Lymphoma (BIA-ALCL): The Lymphoma Study Association (LYSA) Registry Data

Author

Le Bras, Fabien, primary, Gaulard, Philippe, additional, Andre, Marc, additional, Haioun, Corinne, additional, Bosc, Romain, additional, Laurent, Camille, additional, Tortelano, Lionel, additional, Dao, Thua-Ha, additional, Itti, Emmanuel, additional, Malhaire, Caroline, additional, Jean Marc, Schiano de Colella, additional, Bannier, Marie, additional, Bachy, Emmanuel, additional, Slama, Borhane, additional, Fornecker, Luc Mathieu, additional, Oberic, Lucie, additional, Traverse-Glehen, Alexandra, additional, Croix, Manon, additional, Bonnefoy, Julie, additional, Fogarty, Patrick, additional, Bouabbas, Feriel, additional, Amara, Nadia, additional, Fataccioli, Virginie, additional, Ricci, Romain, additional, Cassubie-Mercier, Tania, additional, Kirova, Youlia, additional, Reyal, Fabien, additional, Tilly, Herve, additional, Nicolas-Virelizier, Emmanuelle, additional, Xerri, Luc, additional, and Bonnet, Christophe, additional

Published
2019
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237. Toxicity of locoregional radiotherapy in combination with bevacizumab in patients with non-metastatic breast cancer (TOLERAB): Final long-term evaluation

Author

Clément-Zhao, Alice, primary, Tanguy, Marie-Laure, additional, Cottu, Paul, additional, De La Lande, Brigitte, additional, Bontemps, Patrick, additional, Lemanski, Claire, additional, Baumann, Pierre, additional, Savignoni, Alexia, additional, Levy, Christelle, additional, Peignaux, Karine, additional, Reynaud-Bougnoux, Agnès, additional, Gobillion, Aline, additional, and Kirova, Youlia, additional

Published
2019
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239. Risk of Lymphedema Following Contemporary Treatment for Breast Cancer

Author

Byun, Hwa Kyung, primary, Chang, Jee Suk, additional, Im, Sang Hee, additional, Kirova, Youlia M., additional, Arsene-Henry, Alexandre, additional, Choi, Seo Hee, additional, Cho, Young Up, additional, Park, Hyung Seok, additional, Kim, Jee Ye, additional, Suh, Chang-Ok, additional, Keum, Ki Chang, additional, Sohn, Joo Hyuk, additional, Kim, Gun Min, additional, Lee, Ik Jae, additional, Kim, Jun Won, additional, and Kim, Yong Bae, additional

Published
2019
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242. Salvage Treatment and Survival for Relapsed Follicular Lymphoma Following Primary Radiation Therapy: A Collaborative Study on Behalf of ILROG

Author

Binkley, Michael S., primary, Brady, Jessica L., additional, Hajj, Carla, additional, Chelius, Monica, additional, Chau, Karen, additional, Balogh, Alex, additional, Levis, Mario, additional, Filippi, Andrea Riccardo, additional, Jones, Michael, additional, Ahmed, Sameera, additional, MacManus, Michael, additional, Wirth, Andrew, additional, Oguchi, Masahiko, additional, Vistisen, Anders Krog, additional, Andraos, Therese Youssef, additional, Ng, Andrea K., additional, Aleman, Berthe M.P., additional, Choi, Seo Hee, additional, Kirova, Youlia M., additional, Hardy, Sara, additional, Reinartz, Gabriele, additional, Eich, Hans T., additional, Bratman, Scott V., additional, Constine, Louis S., additional, Suh, Chang-Ok, additional, Dabaja, Bouthaina, additional, El-Galaly, Tarec C., additional, Hodgson, David C., additional, Ricardi, Umberto, additional, Yahalom, Joachim, additional, Mikhaeel, N. George, additional, and Hoppe, Richard T., additional

Published
2019
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243. Photons Without Bolus Versus Electrons With Bolus After Upfront Mastectomy Without Immediate Reconstruction in Breast Cancer Patients

Author

Boulle, Geoffroy, primary, Saint-Martin, Caroline, additional, De La Lande, Brigitte, additional, Laki, Fatima, additional, Bidoz, Nathalie Fournier, additional, Berger, Frédérique, additional, Veret, Arnaud, additional, Bragard, Christelle, additional, Fourquet, Alain, additional, and Kirova, Youlia M., additional

Published
2019
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249. Disseminated Tumor Cells Predict Efficacy of Regional Nodal Irradiation in Early Stage Breast Cancer

Author

Mignot, Fabien, primary, Loirat, Delphine, additional, Dureau, Sylvain, additional, Bataillon, Guillaume, additional, Caly, Martial, additional, Vincent-Salomon, Anne, additional, Berger, Frédérique, additional, Fourquet, Alain, additional, Pierga, Jean-Yves, additional, Kirova, Youlia M., additional, and Bidard, Francois-Clément, additional

Published
2019
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250. Definitive radiotherapy for localized follicular lymphoma staged by 18F-FDG PET-CT: a collaborative study by ILROG

Author

Brady, Jessica L., primary, Binkley, Michael S., primary, Hajj, Carla, primary, Chelius, Monica, primary, Chau, Karen, primary, Balogh, Alex, primary, Levis, Mario, primary, Filippi, Andrea Riccardo, primary, Jones, Michael, primary, Mac Manus, Michael, primary, Wirth, Andrew, primary, Oguchi, Masahiko, primary, Vistisen, Anders Krog, primary, Andraos, Therese Youssef, primary, Ng, Andrea K., primary, Aleman, Berthe M. P., primary, Choi, Seo Hee, primary, Kirova, Youlia, primary, Hardy, Sara, primary, Reinartz, Gabriele, primary, Eich, Hans T., primary, Bratman, Scott V., primary, Constine, Louis S., primary, Suh, Chang-Ok, primary, Dabaja, Bouthaina, primary, El-Galaly, Tarec C., primary, Hodgson, David C., primary, Ricardi, Umberto, primary, Yahalom, Joachim, primary, Hoppe, Richard T., primary, and Mikhaeel, N. George, primary

Published
2019
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