Search

Your search keyword '"Lee, Steve"' showing total 5,331 results
Start Over Author "Lee, Steve"
5,331 results on '"Lee, Steve"'

205. List of Contributors

Author

Buijze, Geert A., primary, Jupiter, Jesse B., additional, Arora, Rohit, additional, Bain, Gregory I., additional, Beeres, Frank J.P., additional, Bhandari, Mohit, additional, Björkman, Anders, additional, de Boer, Bastiaan N.P., additional, Botte, Michael J., additional, Brink, Peter R.G., additional, Buijze, Geert A., additional, Bulstra, Anne Eva J., additional, Casas Contreras, Raúl M., additional, Chammas, Michel, additional, Chammas, Pierre E., additional, Christopoulos, Georgios, additional, Clementson, Martin, additional, Commandeur, Joris P., additional, Coughlin, Timothy A., additional, Dias, Joseph, additional, Doornberg, Job N., additional, Drijkoningen, Tessa, additional, Duckworth, Andrew D., additional, Fernandez, Diego L., additional, Forward, Daren P., additional, Gabl, Markus, additional, Gale, Michael R., additional, Garala, Kanai, additional, Garcia-Elias, Marc, additional, Geissler, William B., additional, Goddard, Nicholas, additional, Gottschalk, Michael B., additional, Gras, Mathilde, additional, Grewal, Ruby, additional, Hannemann, Pascal F.W., additional, Haugstvedt, Jan-Ragnar, additional, Henry, Steven L., additional, Ho, Pak-Cheong, additional, Jake Hamer, M., additional, Johal, Herman, additional, Johnson, Nicholas A., additional, Jørgsholm, Peter, additional, Kakar, Sanjeev, additional, Kalb, Karlheinz, additional, Kastenberger, Tobias, additional, Khouri, Joseph S., additional, Kim, Jong-Pil, additional, Kvernmo, Hebe D., additional, Lee, Steve K., additional, Luria, Shai, additional, Mallee, Wouter H., additional, Mathoulin, Christophe L., additional, Meermans, Geert, additional, Moritomo, Hisao, additional, Moro, Jaydeep, additional, Oka, Kunihiro, additional, Ortega Hernández, Diana M., additional, Pacelli, Lorenzo L., additional, Peraut, Emmanuella, additional, Poeze, Martijn, additional, Prommersberger, Karl-Josef, additional, Rancy, Schneider K., additional, Rhemrev, Steven J., additional, Ring, David, additional, de Roo, Marieke G.A., additional, Saltzman, Eliana B., additional, Schmidle, Gernot, additional, Schmitt, Rainer, additional, Schwarcz, Yonatan, additional, Shin, Alexander Y., additional, Shivji, Faiz S., additional, Singh, Harvinder, additional, Strackee, Simon D., additional, Streekstra, Geert J., additional, Strelzow, Jason A., additional, ten Berg, Paul W., additional, Thompson, Michael A., additional, Thomsen, Niels, additional, Tse, Wing-lim, additional, Turow, Arthur, additional, Vanhees, Matthias, additional, Verstreken, Frederik, additional, de Vos, Maarten J., additional, Wolfe, Scott W., additional, and Wong, Wing-Yee C., additional

Published
2018
Full Text
View/download PDF

207. CX3CR1+ Macrophage Facilitates the Resolution of Allergic Lung Inflammation via Interacting CCL26.

Author

Hyung-Geun Moon, Seung-jae Kim, Ki-Hyun Kim, Young-Mee Kim, Rehman, Jalees, Hyun Lee, Yi-Chien Wu, Seung-Young Lee, Steve, John W. Christman, John W., Steven J. Ackerman, Steven J., Minhyung Kim, Sungyoung You, and Gye Young Park

Abstract

Rationale: The resolution of inflammation is an active process coordinated by mediators and immune cells to restore tissue homeostasis. However, the mechanisms for resolving eosinophilic allergic lung inflammation triggered by inhaled allergens have not been fully elucidated. Objectives: Our objectives were to investigate the cellular mechanism of tissue-resident macrophages involved in the resolution process of eosinophilic lung inflammation. Methods: For the study, we used the institutional review board–approved protocol for human subsegmental bronchoprovocation with allergen, mouse models for allergic lung inflammation, and novel transgenic mice, including a conditional CCL26 knockout. The samples were analyzed using mass cytometry, single-cell RNA sequencing, and biophysical and immunological analyses. Measurements and Main Results: We compared alveolar macrophage (AM) subsets in the BAL before and after allergen provocation. In response to provocation with inhaled allergens, the subsets of AMs are dynamically changed in humans and mice. In the steady state, the AM subset expressing CX3CR1 is a relatively small fraction in bronchoalveolar space and lung tissue but drastically increases after allergen challenges. This subset presents unique patterns of gene expression compared with classical AMs, expressing high C1q family genes. CX3CR1+ macrophages are activated by airway epithelial cell–derived CCL26 via a receptor–ligand interaction. The binding of CCL26 to the CX3CR1+ receptor induces CX3CR1+ macrophages to secrete C1q, subsequently facilitating the clearance of eosinophils. Furthermore, the depletion of CX3CR1 macrophages or CCL26 in airway epithelial cells delays the resolution of allergic lung inflammation displaying prolonged tissue eosinophilia. Conclusions: These findings indicate that the CCL26–CX3CR1 pathway is pivotal in resolving eosinophilic allergic lung inflammation. [ABSTRACT FROM AUTHOR]

Published
2023
Full Text
View/download PDF

219. Circulating tumor DNA as a predictive biomarker in Merkel cell carcinoma

Author

Park, Soo J., primary, Kannan, Aarthi, additional, Harris, Jeremy P., additional, Lacy, Curtis, additional, Daniels, Gregory A., additional, Lee, Steve P., additional, Lambrecht, Nils, additional, Hook, Nicole, additional, Olshan, Perry, additional, Billings, Paul R., additional, Aleshin, Alexey, additional, and Gao, Ling, additional

Published
2022
Full Text
View/download PDF

224. Consensus Statement Supporting the Presence of Onsite Radiation Oncology Departments at VHA Medical Centers

Author

Gutt, Ruchika, Shapiro, Ronald H., Lee, Steve P., Faricy-Anderson, Katherine, Hoffman-Hogg, Lori, Solanki, Abhishek A., Moses, Edwinette, Dawson, George A., and Kelly, Maria D.

Subjects
Special Communication
Abstract

BACKGROUND: Although multiple studies demonstrate that radiotherapy is underused worldwide, the impact that onsite radiation oncology at medical centers has on the use of radiotherapy is poorly studied. The Veterans Health Administration (VHA) Palliative Radiotherapy Taskforce has evaluated the impact of onsite radiation therapy on the use of palliative radiation and has made recommendations based on these findings. OBSERVATIONS: Radiation consults and treatment occur in a more timely manner at VHA centers with onsite radiation therapy compared with VHA centers without onsite radiation oncology. Referring practitioners with onsite radiation oncology less frequently report difficulty contacting a radiation oncologist (0% vs 20%, respectively; P = .006) and patient travel (28% vs 71%, respectively; P < .001) as barriers to referral for palliative radiotherapy. Facilities with onsite radiation oncology are more likely to have multidisciplinary tumor boards (31% vs 3%, respectively; P = .11) and are more likely to be influenced by radiation oncology recommendations at tumor boards (69% vs 44%, respectively; P = .02). CONCLUSIONS: The VHA Palliative Radiotherapy Taskforce recommends the optimization of the use of radiotherapy within the VHA. Radiation oncology services should be maintained where present in the VHA, with consideration for expansion of services to additional facilities. Telehealth should be used to expedite consults and treatment. Hypofractionation should be used, when appropriate, to ease travel burden. Options for transportation services and onsite housing or hospitalization should be understood by treating physicians and offered to patients to mitigate barriers related to travel.

Published
2022

234. Neurotrophin Pathway Receptors NGFR and TrkA Control Perineural Invasion, Metastasis, and Pain in Oral Cancer

Author

Doan, Coleen, primary, Aouizerat, Bradley E., additional, Ye, Yi, additional, Dang, Dongmin, additional, Asam, Kesava, additional, Bhattacharya, Aditi, additional, Howard, Timothy, additional, Patel, Yogin K., additional, Viet, Dan T., additional, Figueroa, Johnny D., additional, Zhong, Jiang F., additional, Thomas, Carissa M., additional, Morlandt, Anthony B., additional, Yu, Gary, additional, Callahan, Nicholas F., additional, Allen, Clint T., additional, Grandhi, Anupama, additional, Herford, Alan S., additional, Walker, Paul C., additional, Nguyen, Khanh, additional, Kidd, Stephanie C., additional, Lee, Steve C., additional, Inman, Jared C., additional, Slater, Jason M., additional, and Viet, Chi T., additional

Published
2022
Full Text
View/download PDF

238. Phase 2, randomized, double-blind trial of EC-18 versus placebo to mitigate the development and time course of oral mucositis from concomitant chemoradiation for head and neck cancer.

Author

Henson, Christina, primary, Clayburgh, Daniel, additional, Lee, Arielle Shebay, additional, Wong, Deborah J.L., additional, Kudrimoti, Mahesh R., additional, Adkins, Douglas, additional, Lee, Steve P., additional, Kalman, Noah, additional, Oppelt, Peter John, additional, Rao, Krishna A., additional, Park, Ji Sun, additional, Oh, Sookyung, additional, Kim, Koeun, additional, Yoon, Sun Young, additional, Sohn, Ki Young, additional, and Sonis, Stephen T., additional

Published
2022
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results