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1,131 results on '"Nishizaki, Kazunori"'

207. Glottic cancer in patients without complaints of hoarseness

Author

Tachibana, Tomoyasu, primary, Orita, Yorihisa, additional, Marunaka, Hidenori, additional, Makihara, Seiichiro, additional, Hirai, Misato, additional, Miki, Kentaro, additional, Ogawara, Yuya, additional, Ishihara, Hisashi, additional, Matsuyama, Yuko, additional, Abe–Fujisawa, Iku, additional, Shimizu, Aiko, additional, Sato, Yasuharu, additional, and Nishizaki, Kazunori, additional

Published
2015
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209. How long should we continue S-1 as adjuvant chemotherapy for squamous cell carcinoma of the head and neck?

Author

Hirai, Misato, primary, Orita, Yorihisa, additional, Takao, Soshi, additional, Tachibana, Tomoyasu, additional, Marunaka, Hidenori, additional, Makihara, Seiichiro, additional, Miki, Kentaro, additional, Noyama, Yasuyuki, additional, Fuji, Sayaka, additional, Torigoe, Akiko, additional, Sato, Yasuharu, additional, and Nishizaki, Kazunori, additional

Published
2015
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211. The impact of chronic rhinosinusitis on long-term survival in lung transplantation recipients.

Author

Kariya, Shin, Okano, Mitsuhiro, Oto, Takahiro, Higaki, Takaya, Haruna, Takenori, Noda, Yohei, and Nishizaki, Kazunori

Subjects
CHRONIC diseases, COMPUTED tomography, ENDOSCOPY, LUNG transplantation, SINUSITIS, TRANSPLANTATION of organs, tissues, etc., SEVERITY of illness index, DESCRIPTIVE statistics, KAPLAN-Meier estimator, DISEASE complications, DIAGNOSIS
Abstract

Conclusions:Chronic rhinosinusitis diagnosed according to the European Position Paper on Rhinosinusitis and Nasal Polyps 2012, not by computed tomography alone, is one of the prognostic factors affecting long-term survival in patients with lung transplantation. Endoscopic sinus surgery might play a beneficial role in the management of lung transplantation recipients with chronic rhinosinusitis. Objective:To show the effect of paranasal sinus infection on post-lung transplantation survival. Method:Lung transplantation recipients were included in this study. Computed tomography was performed before and after lung transplantation. The severity of chronic rhinosinusitis was evaluated by Lund–Mackay scoring system. The survival rate was calculated by the Kaplan–Meier method. Results:One hundred and forty-eight patients received lung transplantation for various indications. Chronic rhinosinusitis was found in 18.9% (28/148) of the lung transplantation recipients. Of 28 patients with chronic rhinosinusitis, seven patients underwent endoscopic sinus surgery due to persistent post-nasal drip. The recipients with chronic rhinosinusitis who did not receive endoscopic sinus surgery (n = 21) showed a significantly lower survival rate as compared to the patients without chronic rhinosinusitis. There was no statistically significant difference in the survival rate between the recipients with (n = 50) and without (n = 98) paranasal sinus abnormality on computed tomography. [ABSTRACT FROM PUBLISHER]

Published
2017
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219. Regulatory T-cell infiltration in tongue squamous cell carcinoma

Author

Hanakawa, Hiroyuki, primary, Orita, Yorihisa, additional, Sato, Yasuharu, additional, Takeuchi, Mai, additional, Ohno, Kyotaro, additional, Gion, Yuka, additional, Tsukahara, Kiyoaki, additional, Tamamura, Ryo, additional, Ito, Toshihiro, additional, Nagatsuka, Hitoshi, additional, Nishizaki, Kazunori, additional, and Yoshino, Tadashi, additional

Published
2014
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222. Association between impaired IL-10 production following exposure to Staphylococcus aureusenterotoxin B and disease severity in eosinophilic chronic rhinosinusitis

Author

Haruna, Takenori, Kariya, Shin, Fujiwara, Tazuko, Higaki, Takaya, Makihara, Seiichiro, Kanai, Kengo, Fujiwara, Rumi, Iwasaki, Satoshi, Noguchi, Yoshihiro, Nishizaki, Kazunori, and Okano, Mitsuhiro

Abstract

IL-10 is a major anti-inflammatory cytokine that prevents inflammation-mediated tissue damage. We characterized the production of IL-10 by sinonasal tissue cells following exposure to Staphylococcus aureusenterotoxin B (SEB), which elicits cellular responses and is associated with the pathogenesis of eosinophilic chronic rhinosinusitis (ECRS).

Published
2018
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223. Leriche operation for parotid gland pathology

Author

Orita, Yorihisa, primary, Ogawara, Toshiaki, additional, Endo, Ryutaro, additional, Fuji, Sayaka, additional, Miki, Kentaro, additional, Hirai, Misato, additional, Noda, Yohei, additional, Marunaka, Hidenori, additional, Tachibana, Tomoyasu, additional, Sato, Yasuharu, additional, and Nishizaki, Kazunori, additional

Published
2014
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234. Diffuse large B-cell lymphoma of the thyroid which caused esophageal fistula

Author

Tachibana, Tomoyasu, primary, Orita, Yorihisa, additional, Fujisawa, Masayoshi, additional, Hiramatsu, Yasushi, additional, Ogawara, Yuya, additional, Matsuyama, Yuko, additional, Abe, Iku, additional, Uchino, Kaori, additional, Morishita, Hirofumi, additional, Nobuhisa, Tetsuji, additional, Uesaka, Koichi, additional, and Nishizaki, Kazunori, additional

Published
2013
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242. Novel and simple prognostic index for nasal natural killer/T‐cell lymphoma

Author

Hanakawa, Hiroyuki, primary, Orita, Yorihisa, additional, Sato, Yasuharu, additional, Takao, Soshi, additional, Marunaka, Hidenori, additional, Morishita, Tokiwa, additional, Yamashita, Yasuhiko, additional, Hori, Yasutaka, additional, Domae, Shuhei, additional, Inokuchi, Ikuo, additional, Akagi, Seiko, additional, Kondo, Eisei, additional, Iwaki, Noriko, additional, Motomiya, Kana, additional, Okumura, Hirokazu, additional, Yoshino, Tadashi, additional, and Nishizaki, Kazunori, additional

Published
2013
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243. Wiskott-Aldrich Syndrome

Author

Kariya, Shin, primary, Nishizaki, Kazunori, additional, Paparella, Michael M., additional, and Cureoglu, Sebahattin, additional

Published
2013
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246. Glottic cancer in patients without complaints of hoarseness.

Author

Tachibana, Tomoyasu, Orita, Yorihisa, Marunaka, Hidenori, Makihara, Seiichiro, Hirai, Misato, Miki, Kentaro, Ogawara, Yuya, Ishihara, Hisashi, Matsuyama, Yuko, Abe–Fujisawa, Iku, Shimizu, Aiko, Sato, Yasuharu, and Nishizaki, Kazunori

Subjects
GLOTTIS cancer, HOARSENESS, CANCER prognosis, LARYNX examination, GASTROSCOPY, DIAGNOSIS
Abstract

Background Few studies have investigated the clinical characteristics of patients with glottic cancer without hoarseness. Methods This retrospective clinical study investigated 371 patients with glottic cancer. Results Thirty-two of the 371 patients (8.6%) with glottic cancer first presented to hospitals with complaints other than hoarseness. Although proportions of stage I and T1 disease were significantly higher among patients without hoarseness than among those with hoarseness ( p = .0036 and p = .0004, respectively), survival curves showed no significant differences between groups ( p = .1334). Conclusion Patients with glottic cancer without complaints of hoarseness were diagnosed at an earlier stage than those with hoarseness. Accumulation of more cases may lead to better survival of patients with glottic cancer without hoarseness compared to those with hoarseness. Checking the larynx of patients without hoarseness or encouraging internists to check the larynx when performing gastroscopic or respiratory examinations may lead to improvement of glottic cancer prognosis. © 2015 Wiley Periodicals, Inc. Head Neck 38: E316-E320, 2016 [ABSTRACT FROM AUTHOR]

Published
2016
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247. Characteristics of audiogram configuration in multiple-system atrophy C and cortical cerebellar atrophy.

Author

Omichi, Ryotaro, Maeda, Yukihide, Sugaya, Akiko, Kataoka, Yuko, Kariya, Shin, Nagayasu, Rie, Nakagawa, Atsuko, Yamashita, Toru, Abe, Koji, and Nishizaki, Kazunori

Subjects
AUDIOMETRIC equipment, BONE conduction, CEREBELLUM diseases, CHI-squared test, CONFIDENCE intervals, FISHER exact test, FRIEDREICH'S ataxia, HEARING disorders, ATROPHY, DATA analysis software, DESCRIPTIVE statistics, ODDS ratio, MANN Whitney U Test
Abstract

Conclusion: The prevalence of low-tone hearing loss (LTHL) is significantly high in spinocerebellar degeneration (SCD) with cerebellar predominance, including multiple-system atrophy C (MSA-C) and cortical cerebellar atrophy (CCA).Objective: This study aimed to test the hypothesis that SCD with cerebellar predominance, MSA-C and CCA may cause auditory symptoms.Methods: The shape and threshold of pure-tone audiograms were evaluated for MSA-C (n = 47; mean (± SD) age, 61.6 ± 8.9 years), CCA (n = 16; 62.8 ± 9.5 years), and age-matched controls (n = 169; 62.5 ± 10.7 years). To differentiate specific hearing loss for MSA-C and CCA from presbycusis, the shape of audiograms was examined based on previously established audiological criteria.Results: When audiogram shape was defined according to audiological criteria, the odds ratio for LTHL in SCD compared to controls was 2.492 (95% confidence interval (CI) = 1.208–5.139;p < 0.05, Pearson’s Chi-square test) in MSA-C and 2.194 (95% CI = 0.709–6.795) in CCA. When the selection of audiogram shape according to these criteria was verified by three certified audiologists, odds ratios for LTHL in MSA-C and CCA were 3.243 (95% CI = 1.320–7.969) and 3.692 (95% CI = 1.052–12.957), respectively, significantly higher than in controls. [ABSTRACT FROM PUBLISHER]

Published
2016
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248. Activation of NLRP3 inflammasome in human middle ear cholesteatoma and chronic otitis media.

Author

Kariya, Shin, Okano, Mitsuhiro, Zhao, Pengfei, Kataoka, Yuko, Yoshinobu, Junko, Maeda, Yukihide, Ishihara, Hisashi, Higaki, Takaya, and Nishizaki, Kazunori

Subjects
PROTEIN analysis, CELL receptors, CHOLESTEATOMA, IMMUNOHISTOCHEMISTRY, INFLAMMATION, RESEARCH methodology, MIDDLE ear, OTITIS media, POLYMERASE chain reaction, PROTEOLYTIC enzymes, RESEARCH funding, TISSUE culture, REVERSE transcriptase polymerase chain reaction, DATA analysis software, DESCRIPTIVE statistics, MANN Whitney U Test, KRUSKAL-Wallis Test
Abstract

Conclusions: The nucleotide-binding oligomerization domain-like receptor protein 3 (NLRP3) inflammasome plays an important role in the pathogenesis of middle ear diseases. Modulation of inflammasome-mediated inflammation may be a novel therapeutic strategy for cholesteatoma and chronic otitis media. Objective: NLRP3 inflammasome is a critical molecule mediating interleukin (IL)-1β responses. However, the expression of NLRP3 in the pathogenesis of cholesteatoma and chronic otitis media has not been fully examined. This study sought to assess the expression of NLRP3, ASC (apoptosis-associated speck-like protein containing a caspase recruitment domain and a pyrin domain), and caspase-1 in middle ear tissues in patients with cholesteatoma or chronic otitis media. Methods: Middle ear tissue samples were obtained from patients with cholesteatoma or chronic otitis media. Control middle ear samples were collected during cochlear implant surgery of patients without middle ear inflammation. The expression of NLRP3, ASC, and caspase-1 were examined by reverse transcription polymerase chain reaction (RT-PCR) assay and immunohistochemical study. Results: The levels of mRNA of NLRP3, ASC, and caspase-1 were significantly elevated in cholesteatoma and chronic otitis media as compared with that of normal controls. The proteins of NLRP3, ASC, and caspase-1 were observed in infiltrating inflammatory cells in cholesteatoma and chronic otitis media. [ABSTRACT FROM AUTHOR]

Published
2016
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250. A Case of Invasive Fungal Sphenoiditis with Nasal Septal Abscess

Author

Makihara, Seiichiro, primary, Takeuchi, Ayako, additional, Yamamoto, Miki, additional, Senoo, Kazunori, additional, Akagi, Seiko, additional, Fukumoto, Aki, additional, Tsumura, Munechika, additional, Ishihara, Hisashi, additional, Kariya, Shin, additional, Okano, Mitsuhiro, additional, and Nishizaki, Kazunori, additional

Published
2013
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