Search

Your search keyword '"Ogasawara, Sadahisa"' showing total 624 results
Start Over Author "Ogasawara, Sadahisa"
624 results on '"Ogasawara, Sadahisa"'

203. Henoch-Schönlein Purpura Complicated by Hepatocellular Carcinoma

Author

Akizue, Naoki, primary, Suzuki, Eiichiro, additional, Yokoyama, Masayuki, additional, Inoue, Masanori, additional, Wakamatsu, Toru, additional, Saito, Tomoko, additional, Kusakabe, Yuko, additional, Ogasawara, Sadahisa, additional, Ooka, Yoshihiko, additional, Tawada, Akinobu, additional, Maru, Yugo, additional, Matsue, Hiroyuki, additional, and Chiba, Tetsuhiro, additional

Published
2017
Full Text
View/download PDF

204. Cytokine release syndrome following durvalumab and tremelimumab in advanced hepatocellular carcinoma: A case report with cytokine and damage‐associated molecular pattern analysis.

Author

Ozaki, Tomomi, Yumita, Sae, Ogasawara, Sadahisa, Fujiya, Makoto, Tsuchiya, Takahiro, Yoshino, Ryohei, Sawada, Midori, Akatsuka, Teppei, Izai, Ryo, Miwa, Chihiro, Yonemoto, Takuya, Fujimoto, Kentaro, Unozawa, Hidemi, Fujiwara, Kisako, Kojima, Ryuta, Kanzaki, Hiroaki, Koroki, Keisuke, Inoue, Masanori, Kobayashi, Kazufumi, and Nakamura, Masato

Subjects
*CYTOKINE release syndrome, *HEPATOCELLULAR carcinoma, *AUTOIMMUNE diseases, *DISSEMINATED intravascular coagulation, *IMMUNE checkpoint inhibitors, *CYTOKINES
Abstract

Cytokine release syndrome (CRS) is a systemic inflammatory syndrome that causes fatal circulatory failure due to hypercytokinemia, and subsequent immune cell hyperactivation caused by therapeutic agents, pathogens, cancers, and autoimmune diseases. In recent years, CRS has emerged as a rare, but significant, immune‐related adverse event linked to immune checkpoint inhibitor therapy. Furthermore, several previous studies suggested that damage‐associated molecular patterns (DAMPs) could be involved in malignancy‐related CRS. In this study, we present a case of severe CRS following combination therapy with durvalumab and tremelimumab for advanced hepatocellular carcinoma, which recurred during treatment, as well as an analysis of cytokine and DAMPs trends. A 35‐year‐old woman diagnosed with hepatocellular carcinoma underwent a partial hepatectomy. Due to cancer recurrence, she started a combination of durvalumab and tremelimumab. Then, 29 days post‐administration, she developed fever and headache, initially suspected as sepsis. Despite antibiotics, her condition worsened, leading to disseminated intravascular coagulation and hemophagocytic syndrome. The clinical course and elevated serum interleukin‐6 levels led to a CRS diagnosis. Steroid pulse therapy was administered, resulting in temporary improvement. However, she relapsed with increased interleukin‐6, prompting tocilizumab treatment. Her condition improved, and she was discharged on day 22. Measurements of inflammatory cytokines interferon‐γ, tumor necrosis factor‐α, and DAMPs, along with interleukin‐6, using preserved serum samples, confirmed marked elevation at CRS onset. CRS can occur after the administration of any immune checkpoint inhibitor, with the most likely trigger being the release of DAMPs associated with tumor collapse. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

206. Prognostic Significance of Concurrent Hypovascular and Hypervascular Nodules in Patients with Hepatocellular Carcinoma

Author

Ogasawara, Sadahisa, primary, Chiba, Tetsuhiro, additional, Motoyama, Tenyu, additional, Kanogawa, Naoya, additional, Saito, Tomoko, additional, Shinozaki, Yusuke, additional, Suzuki, Eiichiro, additional, Ooka, Yoshihiko, additional, Tawada, Akinobu, additional, Kato, Hideyuki, additional, Okabe, Shinichiro, additional, Kanai, Fumihiko, additional, Yoshikawa, Masaharu, additional, and Yokosuka, Osamu, additional

Published
2016
Full Text
View/download PDF

208. Dexamethasone for the prevention of transcatheter arterial chemoembolization-induced fever, nausea, vomiting, and anorexia in patients with hepatocellular carcinoma: A randomized, double-blind, placebo-controlled trial.

Author

Ogasawara, Sadahisa, primary, Chiba, Tetsuhiro, additional, Ooka, Yoshihiko, additional, Suzuki, Eiichiro, additional, Kanogawa, Naoya, additional, Motoyama, Tenyu, additional, Tawada, Akinobu, additional, Nakagawa, Tomoo, additional, Nagai, Kazue, additional, Hanaoka, Hideki, additional, Kanai, Fumihiko, additional, and Yokosuka, Osamu, additional

Published
2016
Full Text
View/download PDF

209. Successful treatment of two patients with hepatocellular carcinoma exhibiting severe pancytopenia caused by aplastic anemia

Author

Maeda, Takahiro, primary, Chiba, Tetsuhiro, additional, Ooka, Yoshihiko, additional, Yokoyama, Masayuki, additional, Wakamatsu, Toru, additional, Inoue, Masanori, additional, Kusakabe, Yuko, additional, Saito, Tomoko, additional, Ogasawara, Sadahisa, additional, Suzuki, Eiichiro, additional, Tawada, Akinobu, additional, Sakaida, Emiko, additional, Nakaseko, Chiaki, additional, Iseki, Toru, additional, Kishimoto, Takashi, additional, and Yokosuka, Osamu, additional

Published
2016
Full Text
View/download PDF

210. A case of hepatocellular carcinoma with spontaneous regression of a tumor thrombus invading the main portal trunk

Author

Ooka, Yoshihiko, primary, Chiba, Tetsuhiro, additional, Inoue, Masanori, additional, Wakamatsu, Toru, additional, Saito, Tomoko, additional, Sekimoto, Tadashi, additional, Ogasawara, Sadahisa, additional, Suzuki, Eiichiro, additional, Tawada, Akinobu, additional, Maruyama, Hutoshi, additional, Kishimoto, Takashi, additional, and Yokosuka, Osamu, additional

Published
2016
Full Text
View/download PDF

211. Sustained Virologic Response at 24 Weeks after the End of Treatment Is a Better Predictor for Treatment Outcome in Real-World HCV-Infected Patients Treated by HCV NS3/4A Protease Inhibitors with Peginterferon plus Ribavirin

Author

Kanda, Tatsuo, primary, Nakamoto, Shingo, additional, Sasaki, Reina, additional, Nakamura, Masato, additional, Yasui, Shin, additional, Haga, Yuki, additional, Ogasawara, Sadahisa, additional, Tawada, Akinobu, additional, Arai, Makoto, additional, Mikami, Shigeru, additional, Imazeki, Fumio, additional, and Yokosuka, Osamu, additional

Published
2016
Full Text
View/download PDF

213. Intensity-Based Assessment of Microbubble-Enhanced Ultrasonography: Phase-Related Diagnostic Ability for Cellular Differentiation of Hepatocellular Carcinoma

Author

Kondo, Takayuki, primary, Maruyama, Hitoshi, additional, Kiyono, Soichiro, additional, Sekimoto, Tadashi, additional, Shimada, Taro, additional, Takahashi, Masanori, additional, Ogasawara, Sadahisa, additional, Suzuki, Eiichiro, additional, Ooka, Yoshihiko, additional, Tawada, Akinobu, additional, Chiba, Tetsuhiro, additional, Kanai, Fumihiko, additional, and Yokosuka, Osamu, additional

Published
2015
Full Text
View/download PDF

216. Sustained virologic response achieved after curative treatment of hepatitis C virus‐related hepatocellular carcinoma as an independent prognostic factor

Author

Kanogawa, Naoya, primary, Ogasawara, Sadahisa, additional, Chiba, Tetsuhiro, additional, Saito, Tomoko, additional, Motoyama, Tenyu, additional, Suzuki, Eiichiro, additional, Ooka, Yoshihiko, additional, Tawada, Akinobu, additional, Kanda, Tatsuo, additional, Mikami, Shigeru, additional, Azemoto, Ryosaku, additional, Kaiho, Takashi, additional, Shinozaki, Masami, additional, Ohtsuka, Masayuki, additional, Miyazaki, Masaru, additional, and Yokosuka, Osamu, additional

Published
2015
Full Text
View/download PDF

217. Fatal Diaphragmatic Hernia following Radiofrequency Ablation for Hepatocellular Carcinoma: A Case Report and Literature Review

Author

Saito, Tomoko, primary, Chiba, Tetsuhiro, additional, Ogasawara, Sadahisa, additional, Inoue, Masanori, additional, Wakamatsu, Toru, additional, Motoyama, Tenyu, additional, Kanogawa, Naoya, additional, Suzuki, Eiichiro, additional, Ooka, Yoshihiko, additional, Tawada, Akinobu, additional, Matsubara, Hisahiro, additional, and Yokosuka, Osamu, additional

Published
2015
Full Text
View/download PDF

218. A Prognostic Score for Patients with Intermediate-Stage Hepatocellular Carcinoma Treated with Transarterial Chemoembolization

Author

Ogasawara, Sadahisa, primary, Chiba, Tetsuhiro, additional, Ooka, Yoshihiko, additional, Kanogawa, Naoya, additional, Motoyama, Tenyu, additional, Suzuki, Eiichiro, additional, Tawada, Akinobu, additional, Azemoto, Ryosaku, additional, Shinozaki, Masami, additional, Yoshikawa, Masaharu, additional, and Yokosuka, Osamu, additional

Published
2015
Full Text
View/download PDF

221. Successful treatment of three elderly patients aged ≥90 years with hepatocellular carcinoma

Author

Saito, Tomoko, primary, Chiba, Tetsuhiro, additional, Wakamatsu, Toru, additional, Inoue, Masanori, additional, Kusakabe, Yuko, additional, Sekimoto, Tadashi, additional, Maruyama, Hitoshi, additional, Ogasawara, Sadahisa, additional, Suzuki, Eiichiro, additional, Ooka, Yoshihiko, additional, Tawada, Akinobu, additional, and Yokosuka, Osamu, additional

Published
2015
Full Text
View/download PDF

224. Asia-Pacific clinical practice guidelines on the management of hepatocellular carcinoma: a 2017 update.

Author

Omata, Masao, Cheng, Ann-Lii, Kokudo, Norihiro, Kudo, Masatoshi, Lee, Jeong, Jia, Jidong, Tateishi, Ryosuke, Han, Kwang-Hyub, Chawla, Yoghesh, Shiina, Shuichiro, Jafri, Wasim, Payawal, Diana, Ohki, Takamasa, Ogasawara, Sadahisa, Chen, Pei-Jer, Lesmana, Cosmas, Lesmana, Laurentius, Gani, Rino, Obi, Shuntaro, and Dokmeci, A.

Abstract

There is great geographical variation in the distribution of hepatocellular carcinoma (HCC), with the majority of all cases worldwide found in the Asia-Pacific region, where HCC is one of the leading public health problems. Since the 'Toward Revision of the Asian Pacific Association for the Study of the Liver (APASL) HCC Guidelines' meeting held at the 25th annual conference of the APASL in Tokyo, the newest guidelines for the treatment of HCC published by the APASL has been discussed. This latest guidelines recommend evidence-based management of HCC and are considered suitable for universal use in the Asia-Pacific region, which has a diversity of medical environments. [ABSTRACT FROM AUTHOR]

Published
2017
Full Text
View/download PDF

225. Primary analysis of a phase II study of atezolizumab plus bevacizumab for TACE-unsuitable patients with tumor burden beyond up-to-seven criteria in intermediate-stage hepatocellular carcinoma: REPLACEMENT study.

Author

Ueshima, Kazuomi, Kudo, Masatoshi, Tsuchiya, Kaoru, Kato, Naoya, Yamashita, Tatsuya, Shimose, Shigeo, Numata, Kazushi, Kodama, Yuzo, Tanaka, Yasuhito, Kuroda, Hidekatsu, Itoh, Shinji, Aikata, Hiroshi, Hiraoka, Atsushi, Moriguchi, Michihisa, Wada, Yoshiyuki, Nakao, Kazuhiko, Tateishi, Ryosuke, Ogasawara, Sadahisa, Yamamoto, Kouji, and Ikeda, Masafumi

Published
2023
Full Text
View/download PDF

226. A phase 1b study of E7386, a CREB-binding protein (CBP)/β-catenin interaction inhibitor, in combination with lenvatinib in patients with advanced hepatocellular carcinoma.

Author

Ikeda, Masafumi, Kato, Naoya, Kondo, Shunsuke, Inaba, Yoshitaka, Ueshima, Kazuomi, Sasaki, Mitsuhito, Kanzaki, Hiroaki, Ida, Hiroshi, Imaoka, Hiroshi, Minami, Yasunori, Mitsunaga, Shuichi, Nishida, Naoshi, Ogasawara, Sadahisa, Watanabe, Kazuo, Sahara, Takatoshi, Hayata, Nozomi, Yamamuro, Shintaro, Kimura, Takayuki, Tamai, Toshiyuki, and Kudo, Masatoshi

Published
2023
Full Text
View/download PDF

227. Successful Interventional Treatment for Arterioportal Fistula Caused by Radiofrequency Ablation for Hepatocellular Carcinoma

Author

Kanogawa, Naoya, primary, Chiba, Tetsuhiro, additional, Ogasawara, Sadahisa, additional, Ooka, Yoshihiko, additional, Suzuki, Eiichiro, additional, Motoyama, Tenyu, additional, Saito, Tomoko, additional, Sekimoto, Tadashi, additional, Tawada, Akinobu, additional, Maruyama, Hitoshi, additional, Yoshikawa, Masaharu, additional, and Yokosuka, Osamu, additional

Published
2014
Full Text
View/download PDF

229. Histone lysine methyltransferase SUV39H1 is a potent target for epigenetic therapy of hepatocellular carcinoma

Author

Chiba, Tetsuhiro, primary, Saito, Tomoko, additional, Yuki, Kaori, additional, Zen, Yoh, additional, Koide, Shuhei, additional, Kanogawa, Naoya, additional, Motoyama, Tenyu, additional, Ogasawara, Sadahisa, additional, Suzuki, Eiichiro, additional, Ooka, Yoshihiko, additional, Tawada, Akinobu, additional, Otsuka, Masayuki, additional, Miyazaki, Masaru, additional, Iwama, Atsushi, additional, and Yokosuka, Osamu, additional

Published
2014
Full Text
View/download PDF

231. Intracranial Metastasis in a Patient with Hepatocellular Carcinoma and Gastric Cancer

Author

Tawada, Akinobu, primary, Chiba, Tetsuhiro, additional, Ooka, Yoshihiko, additional, Yokota, Hajime, additional, Kanogawa, Naoya, additional, Motoyama, Tenyu, additional, Saito, Tomoko, additional, Ogasawara, Sadahisa, additional, Suzuki, Eiichiro, additional, Hanari, Naoyuki, additional, Matsubara, Hisahiro, additional, Saeki, Naokatsu, additional, Kambe, Michiyo, additional, Kishimoto, Takashi, additional, Nakatani, Yukio, additional, and Yokosuka, Osamu, additional

Published
2014
Full Text
View/download PDF

235. Disulfiram Eradicates Tumor-Initiating Hepatocellular Carcinoma Cells in ROS-p38 MAPK Pathway-Dependent and -Independent Manners

Author

Chiba, Tetsuhiro, primary, Suzuki, Eiichiro, additional, Yuki, Kaori, additional, Zen, Yoh, additional, Oshima, Motohiko, additional, Miyagi, Satoru, additional, Saraya, Atsunori, additional, Koide, Shuhei, additional, Motoyama, Tenyu, additional, Ogasawara, Sadahisa, additional, Ooka, Yoshihiko, additional, Tawada, Akinobu, additional, Nakatsura, Tetsuya, additional, Hayashi, Takehiro, additional, Yamashita, Taro, additional, Kaneko, Syuichi, additional, Miyazaki, Masaru, additional, Iwama, Atsushi, additional, and Yokosuka, Osamu, additional

Published
2014
Full Text
View/download PDF

236. Effect of Previous Interferon-based Therapy on Recurrence after Curative Treatment of Hepatitis C Virus-related Hepatocellular Carcinoma

Author

Saito, Tomoko, primary, Chiba, Tetsuhiro, additional, Suzuki, Eiichiro, additional, Shinozaki, Masami, additional, Goto, Nobuaki, additional, Kanogawa, Naoya, additional, Motoyama, Tenyu, additional, Ogasawara, Sadahisa, additional, Ooka, Yoshihiko, additional, Tawada, Akinobu, additional, Kanda, Tatsuo, additional, Miyazaki, Masaru, additional, and Yokosuka, Osamu, additional

Published
2014
Full Text
View/download PDF

239. A prospective study exploring the safety and efficacy of lenvatinib for patients with advanced hepatocellular carcinoma potential in current real-world practice.

Author

Kobayashi, Kazufumi, Ogasawara, Sadahisa, Maruta, Susumu, Okubo, Tomomi, Moriguchi, Michihisa, Kanzaki, Hiroaki, Koroki, Keisuke, Kanogawa, Naoya, Shiko, Yuki, Inaba, Yosuke, Nakamura, Kazuyoshi, Azemoto, Ryosaku, Ito, Kenji, Okabe, Shinichiro, Atsukawa, Masanori, Itobayashi, Ei, Ikeda, Masafumi, Morimoto, Naoki, Itoh, Yoshito, and Kato, Naoya

Published
2023
Full Text
View/download PDF

240. Coronal reformatted CT images contribute to the precise evaluation of the radiofrequency ablative margin for hepatocellular carcinoma

Author

Motoyama, Tenyu, primary, Ogasawara, Sadahisa, additional, Chiba, Tetsuhiro, additional, Higashide, Takashi, additional, Yokota, Hajime, additional, Kanogawa, Naoya, additional, Suzuki, Eiichiro, additional, Ooka, Yoshihiko, additional, Tawada, Akinobu, additional, Irie, Ryosuke, additional, Ochi, Shigehiro, additional, Masuda, Yoshitada, additional, Uno, Takashi, additional, and Yokosuka, Osamu, additional

Published
2013
Full Text
View/download PDF

241. Clinical features and natural history of portal vein thrombosis after radiofrequency ablation for hepatocellular carcinoma in Japan

Author

Shimada, Taro, primary, Maruyama, Hitoshi, additional, Kondo, Takayuki, additional, Sekimoto, Tadashi, additional, Takahashi, Masanori, additional, Motoyama, Tenyu, additional, Ogasawara, Sadahisa, additional, Suzuki, Eiichiro, additional, Ooka, Yoshihiko, additional, Tawada, Akinobu, additional, Chiba, Tetsuhiro, additional, Kanai, Fumihiko, additional, Okabe, Shinichiro, additional, Yoshikawa, Masaharu, additional, and Yokosuka, Osamu, additional

Published
2013
Full Text
View/download PDF

242. Metformin, a Diabetes Drug, Eliminates Tumor-Initiating Hepatocellular Carcinoma Cells

Author

Saito, Tomoko, primary, Chiba, Tetsuhiro, additional, Yuki, Kaori, additional, Zen, Yoh, additional, Oshima, Motohiko, additional, Koide, Shuhei, additional, Motoyama, Tenyu, additional, Ogasawara, Sadahisa, additional, Suzuki, Eiichiro, additional, Ooka, Yoshihiko, additional, Tawada, Akinobu, additional, Tada, Motohisa, additional, Kanai, Fumihiko, additional, Takiguchi, Yuichi, additional, Iwama, Atsushi, additional, and Yokosuka, Osamu, additional

Published
2013
Full Text
View/download PDF

245. Successful Non-surgical Treatment of Ruptured Pyogenic Liver Abscess

Author

Motoyama, Tenyu, primary, Ogasawara, Sadahisa, additional, Chiba, Tetsuhiro, additional, Suzuki, Eiichiro, additional, Yokota, Hajime, additional, Haga, Yuki, additional, Kanogawa, Naoya, additional, Saito, Tomoko, additional, Ooka, Yoshihiko, additional, Tawada, Akinobu, additional, Kanai, Fumihiko, additional, and Yokosuka, Osamu, additional

Published
2013
Full Text
View/download PDF

246. Successful Resection of Intracranial Metastasis of Hepatocellular Carcinoma

Author

Okimoto, Kenichiro, primary, Ogasawara, Sadahisa, additional, Chiba, Tetsuhiro, additional, Kanai, Fumihiko, additional, Yokota, Hajime, additional, Motoyama, Tenyu, additional, Suzuki, Eiichiro, additional, Ooka, Yoshihiko, additional, Tawada, Akinobu, additional, Iwadate, Yasuo, additional, Saeki, Naokatsu, additional, and Yokosuka, Osamu, additional

Published
2013
Full Text
View/download PDF

247. Simultaneous Resection of Disseminated Hepatocellular Carcinoma and Colon Cancer

Author

Haga, Yuki, primary, Chiba, Tetsuhiro, additional, Ohira, Gaku, additional, Kanai, Fumihiko, additional, Yokota, Hajime, additional, Motoyama, Tenyu, additional, Ogasawara, Sadahisa, additional, Suzuki, Eiichiro, additional, Ooka, Yoshihiko, additional, Tawada, Akinobu, additional, Miyauchi, Hideaki, additional, Matubara, Hisahiro, additional, and Yokosuka, Osamu, additional

Published
2013
Full Text
View/download PDF

248. Post-progression survival in patients with advanced hepatocellular carcinoma resistant to sorafenib.

Author

Ogasawara, Sadahisa, Chiba, Tetsuhiro, Ooka, Yoshihiko, Suzuki, Eiichiro, Kanogawa, Naoya, Saito, Tomoko, Motoyama, Tenyu, Tawada, Akinobu, Kanai, Fumihiko, and Yokosuka, Osamu

Subjects
DRUG side effects, HEPATOCELLULAR carcinoma, SURVIVAL analysis (Biometry), SURVIVAL, INSTITUTIONAL review boards, CLINICAL trial registries, PROPORTIONAL hazards models, DISEASE progression, SORAFENIB, PROGNOSIS
Published
2016
Full Text
View/download PDF

249. Hepatic Sarcoidosis with an Increased Serum Level of Immunoglobulin G4

Author

Inoue, Masanori, primary, Chiba, Tetsuhiro, additional, Zen, Yoh, additional, Yokota, Hajime, additional, Kanda, Tatsuo, additional, Ogasawara, Sadahisa, additional, Sugiyama, Harutoshi, additional, Arai, Makoto, additional, Kanai, Fumihiko, additional, Ogawa, Makoto, additional, Imazeki, Fumio, additional, and Yokosuka, Osamu, additional

Published
2012
Full Text
View/download PDF

250. Incidental tumor necrosis caused by the interventional alteration of hepatic arterial flow in patients with advanced hepatocellular carcinoma.

Author

Suzuki, Eiichiro, Ooka, Yoshihiko, Chiba, Tetsuhiro, Kobayashi, Kazufumi, Kanogawa, Naoya, Motoyama, Tenyu, Saito, Tomoko, Ogasawara, Sadahisa, Tawada, Akinobu, and Yokosuka, Osamu

Abstract

Hepatic arterial infusion chemotherapy (HAIC) is one of the approaches used to treat advanced hepatocellular carcinoma (HCC). Here, we describe 2 cases involving unexpected tumor necrosis after interventional alteration of the hepatic arterial flow during implantation of a port-catheter system for HAIC. Case 1 involved a 42-year-old man with diffuse HCC accompanied by a tumor thrombus in the main trunk of the portal vein. After the right hepatic artery (RHA) derived from the superior mesenteric artery (SMA) was occluded by coils, a port-catheter system was successfully implanted using the gastroduodenal artery (GDA) coil method. The next day, he developed a fever and had right upper abdominal pain. A marked increase in transaminase and lactate dehydrogenase levels was observed. Contrast-enhanced computed tomography (CT) showed tumor necrosis in both the parenchymal tumor and portal vein tumor thrombus. Case 2 involved a 62-year-old man diagnosed with a large HCC located in segments VII and VIII of the liver and abdominal lymph node metastasis. As in case 1, angiography revealed the RHA branched from the SMA. After the replaced RHA and right gastric artery were embolized with coils, a port-catheter system was successfully implanted. Although he showed neither clinical symptoms nor abnormal laboratory data the next day, contrast-enhanced CT revealed tumor necrosis in a large part of the HCC lesion. In conclusion, careful attention is required in the interventional alteration of hepatic arterial flow for implantation of a port-catheter system for HAIC against advanced HCC. [ABSTRACT FROM AUTHOR]

Published
2015
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results