Search

Your search keyword '"Perlovich, German"' showing total 704 results
Start Over Author "Perlovich, German"
704 results on '"Perlovich, German"'

218. Vapor pressure and sublimation thermodynamics of aminobenzoic acid, nicotinic acid, and related amido-derivatives.

Author

Volkova, Tatyana, Blokhina, Svetlana, Ryzhakov, Alex, Sharapova, Angelica, Ol'khovich, Marina, and Perlovich, German

Subjects
VAPOR pressure, SUBLIMATION (Chemistry), THERMODYNAMICS, AMINOBENZOIC acids, NIACIN, CHEMICAL derivatives
Abstract

The inert gas transpiration technique was used for measuring the vapor pressures of the following biologically active compounds: 4-aminobenzoic acid, nicotinic acid, 4-aminobenzamide, 4-pyridinecarboxamide, N-(2-chloro-3-pyridinyl)-benzenesulfonamide, 4-nitro- N-2-thiazolyl-benzenesulfonamide, and 4-amino- N-(5-methyl-3-isoxazolyl)-benzenesulfon-amide in the appropriate temperature ranges. Differential scanning calorimetric analysis was applied to obtain the temperature and molar enthalpy of melting of the compounds studied. Standard molar enthalpies, entropies, and Gibbs energies of sublimation were derived at T = 298.15 K from the temperature dependences of the vapor pressure of the compounds. The obtained results allowed the estimation of the relationship between the sublimation thermodynamic parameters and the thermophysical properties of the substances. Correlation equations were used for calculating the saturated vapor pressures on the basis of the melting temperatures, sublimation enthalpies, and physicochemical HYBOT descriptors. [ABSTRACT FROM AUTHOR]

Published
2016
Full Text
View/download PDF

248. Vapor pressures and thermodynamic sublimation of antitubercular drugs.

Author

Blokhina, Svetlana, Sharapova, Angelica, Ol'khovich, Marina, Volkova, Tatyana, and Perlovich, German

Subjects
VAPOR pressure, THERMODYNAMICS, ANTITUBERCULAR agents, SUBLIMATION (Chemistry), NOBLE gases, HYDRAZIDES
Abstract

The temperature dependencies of the saturated vapor pressure for antituberculous drug compounds: pyrazinecarboxamide and three isonicotinic acid hydrazides were obtained using the method of inert gas-carrier transfer. The standard sublimation molar enthalpies, entropies and Gibbs energies were derived at T = 298.15 K. The temperature and fusion molar enthalpy of the compounds were measured using the differential scanning calorimetry technique. The influence of the structure of the studied compounds on the crystal lattice energy and volatility was analyzed. It was estimated that the saturated vapor pressure of the studied substances decreases when the molecule polarizability and donor-acceptor ability increase. [ABSTRACT FROM AUTHOR]

Published
2015
Full Text
View/download PDF

250. Impactof Sulfonamide Structure on Solubility andTransfer Processes in Biologically Relevant Solvents.

Author

Perlovich, German L., Kazachenko, Vladimir P., Strakhova, Nadezda N., and Raevsky, Oleg A.

Subjects
*SULFONAMIDES, *MOLECULAR structure, *SOLUBILITY, *HYDROPHILIC compounds, *ISOTHERMAL processes, *SOLVENT analysis
Abstract

Solubilityvalues of 39 sulfonamides in water, 1-octanol, and 1-hexanewere determined by the isothermal saturation method. Thermophysicalcharacteristics of fusion processes (melting points and fusion enthalpies)of the selected substances were measured by the DSC method. The impactof molecule structural modification on solubility processes in thesolvents was analyzed. Transfer processes from water to 1-octanol,water to 1-hexane, and 1-hexane to 1-octanol were studied. Correlationequations connecting Gibbs energies of the solubility and the transferprocesses with physicochemical descriptors and thermophysical characteristicswere obtained. [ABSTRACT FROM AUTHOR]

Published
2014
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results