Search

Your search keyword '"Reichart B"' showing total 2,230 results
Start Over Author "Reichart B"
2,230 results on '"Reichart B"'

203. Langzeitergebnisse nach homologem Aortenklappen- und Aortenwurzelersatz bei florider Aortenklappenendokarditis

Author

Reichart, B., Sievers, H. H., Hetzer, R., Klose, Holger, Reichart, B., Sievers, H. H., Hetzer, R., and Klose, Holger

Abstract

Einleitung: Die Implantation kryokonservierter allogener Aortenklappen stellt heutzutage eine effektive operative Technik dar, um in schweren Fällen einer floriden Aortenklappenendokarditis exzellente postoperative Ergebnisse zu erzielen. Diese Studie demonstriert die Langzeitergebnisse im Deutschen Herzzentrum Berlin über einen Zeitraum von 17 Jahren. Material und Methoden: Zwischen dem 1.Januar 1987 und 31.Dezember 2003 wurden bei 203 Patienten mit florider Aortenklappenendokarditis kryokonservierte Aortenklappenallografts implantiert (in subkoronarer Implantationstechnik n=107 und durch totalen Aortenwurzelersatz n=96). Das mittlere Alter der Patienten betrug 51,3 Jahre (2-82 Jahre). Darunter waren 42 Frauen und 161 Männer. 161 Patienten zeigten präoperativ eine anuläre Aortenwurzelabszeßbildung. Ergebnisse: Die 30-Tage-Mortalität (mit Anulusabszeß) betrug insgesamt 21,1% (23,6%): bei nativer Aortenklappenendokarditis 14,9% (17,5%) und bei Prothesen-endokarditis 29,2% (29,6%). Nach 17 Jahren waren 70,4+3,6% und 78,6+6,3% (p=0,24) der Patienten mit und ohne präoperativem Anulusabszeß am Leben. Bei 12 Patienten mit Anulusabszeß trat eine Allograft-Re-Infektion auf, die aktualisierte Freiheit von Reinfektion betrug 91,6+2,4% nach 17 Jahren. Insgesamt wurden 37 Patienten reoperiert, die aktualisierte Freiheit von Reoperation betrug 75,0+3,7% nach 17 Jahren. Die aktualisierte Freiheit von Explantation der Allografts wegen Strukturalteration betrug bei den Patienten mit Anulusabszeß nach 17 Jahren 96,0+2,0%. Thrombembolische Ereignisse traten nicht auf. Die Univarianzanalyse identifizierte die Allograft-Re-Infektion (p=0,0001) und zu klein bemessene Allografts (p=0,001) als Risikofaktoren für eine Reoperation sowohl bei nativer als auch Prothesenendokarditis. Schlußfolgerung: Aortenklappenallografts zeigen bei florider Aortenklappenendokarditis mit Anulusabszeß exzellente Langzeitresultate. Die 30-Tage–Mortalität wird hinsichtlich der Schwere der Erkrankung akzeptiert, Objective: Cryopreserved aortic valve homografts have become an accepted valve substitute in acute aortic valve endocarditis, but long-term studies of valve function are largely unavailable. This survey represents our observations over a period of 17 years. Material and methods: Between February 9, 1987 and October 30, 2003, 203 patients with infective aortic valve endocarditis underwent allograft replacement of the aortic valve (free-hand subcoronary technique, n=107 and root replacement, n=96). The patients’ age ranged between 2 and 82 years with a mean age of 51.3 years. The survey included 42 females and 161 males. 161 had infected aortic root with ring abscesses. Results: The hospital mortality of patients with native and prosthetic endocarditis complicated by periannular abscess was 14.9% (17.5%) and 29.2 % (29.6%) respectively making an overall hospital mortality of 21.2% (23.6%). 17 years patient survival in patients with and without periannular abscess was 70.4+3.6% and 78.6+6.3% (p=0,24) respectively. There were 12 events of recurrent endocarditis in patients with periannular abscess, giving an actuarial freedom of 91.6+2.4% at 17 years. Reoperation was performed in 37 patients for a variety of reasons, and overall freedom from reoperation was 75.0+3.7% at 17 years. Freedom from explantation for structural valve deterioration was 96.0+2.0% at 17 years for patients with periannular abcess. No thrombembolic event was evident. Univariable analysis identified recurrent endocarditis (p=0.0001) and undersized allograft (p=0.001) as risk factors for reoperation for both native and prosthetic aortic valve endocarditis. No risk factors for hospital mortality were found. Conclusion: Aortic allograft offers an excellent long-term clinical result in patients with infective aortic valve endocarditis with associated periannular abscess. Operative mortality is acceptable based on the severity of aortic pathology, with low evidence of recurrent endocarditis and no thrombe

Published
2005

204. 204 Long-Term Benefit of Tacrolimus over Cyclosporine Preventing Cardiac Allograft Vasculopathy (CAV) after Heart Transplantation: 10-Year Results of a Prospective Randomized Trial Comparing Tacrolimus Versus Cyclosporine Both in Combination with Mycophenolate Mofetil

Author

Guethoff, S., primary, Meiser, B., additional, Schramm, R., additional, Ueberfuhr, P., additional, Hagl, C., additional, Reichart, B., additional, and Kaczmarek, I., additional

Published
2012
Full Text
View/download PDF

220. 507 Value of Early Post-Transplant Biopsies for Predicting Long-Term Major Adverse Cardiac Events (MACE) in Heart Transplant Patients

Author

Labarrere, C.A., primary, Woods, J.R., additional, Hardin, J.W., additional, Campana, G.L., additional, Ortiz, M.A., additional, Jaeger, B.R., additional, Reichart, B., additional, Baldridge, L.A., additional, Bonnin, J.M., additional, Currin, A., additional, Cosgrove, S.K., additional, Kirlin, P.C., additional, Pitts, D.E., additional, O'Donnell, J.A., additional, Hormuth, D.A., additional, and Wozniak, T.C., additional

Published
2011
Full Text
View/download PDF

228. 144 Single-Center Experience with 360 Lung Transplantations: Influence of Different Immunosuppressive Protocols on Long-Term Survival, Acute Rejection and on Bronchiolitis-Obliterans-Syndrome (BOS)

Author

Brenner, P., primary, Beiras-Fernandez, A., additional, Winter, H., additional, Niazi, M.A., additional, Kur, F., additional, Behr, J., additional, Neurohr, C., additional, Hatz, R., additional, Frey, L., additional, Czerner, S., additional, Bittmann, I., additional, Bauer, A., additional, Reichenspurner, H., additional, Reichart, B., additional, and Überfuhr, P., additional

Published
2011
Full Text
View/download PDF

229. 506 Value of the First Biopsy for Predicting Cardiac Allograft Vasculopathy (CAV) in Heart Transplant Patients

Author

Labarrere, C.A., primary, Woods, J.R., additional, Hardin, J.W., additional, Campana, G.L., additional, Ortiz, M.A., additional, Jaeger, B.R., additional, Reichart, B., additional, Baldridge, L.A., additional, Bonnin, J.M., additional, Currin, A., additional, Cosgrove, S.K., additional, Kirlin, P.C., additional, Pitts, D.E., additional, O'Donnell, J.A., additional, Hormuth, D.A., additional, and Wozniak, T.C., additional

Published
2011
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results