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207. Contributors

Author

Abeles, Aryeh M., primary, Abelson, Abby G., additional, Abhishek, Abhishek, additional, Abramson, Steven B., additional, Adams, Michael A., additional, Adlam, David M., additional, Aigner, Thomas, additional, Akira, Shizuo, additional, Aksentijevich, Ivona, additional, Aletaha, Daniel, additional, Aliprantis, Antonios O., additional, Allaart, Cornelia F., additional, Allen, Pamela G., additional, Altman, Roy D., additional, Aringer, Martin, additional, Ascherman, Dana P., additional, Assassi, Shervin, additional, Atamas, Sergei P., additional, Baer, Alan N., additional, Baeten, Dominique, additional, Baker, Nancy, additional, Balsa, Alejandro, additional, Barnsley, Les, additional, Bathon, Joan M., additional, Becker, Michael A., additional, Belch, Jill JF, additional, Bellamy, Nicholas, additional, Bellido, Teresita, additional, Benitez, R. Michael, additional, Benjamin, Michael, additional, Beresford, Michael W., additional, Berman, Brian M., additional, Bermas, Bonnie Lee, additional, Bertsias, George, additional, Bilezikian, John P., additional, Blazar, Philip E., additional, Bleasel, Jane F., additional, Böhm, Markus, additional, Boileau, Christelle, additional, Bolster, Marcy B., additional, Bombardieri, Stefano, additional, Bonnick, Sydney, additional, Boumpas, Dimitrios T., additional, Brasington, Richard D., additional, Breedveld, Ferdinand, additional, Brien, Earl W., additional, Brower, Anne C., additional, Brown, Matthew A., additional, Bruce, Ian N., additional, Bugbee, William D., additional, Bukhari, Marwan A.S., additional, Burgos-Vargas, Rubén, additional, Burns, Jane C., additional, Burr, David B., additional, Cagnoli, Patricia C., additional, Calabrese, Leonard H., additional, Callen, Jeffrey P., additional, Canoso, Juan J., additional, Cavallo, Sabrina, additional, Cawston, Tim E., additional, Chard, Michael Denis, additional, Chen, Lan X., additional, Choy, Ernest H.S., additional, Clauw, Daniel J., additional, Clements, Philip J., additional, Colburn, Nona T., additional, Coleman, Laura A., additional, Conaghan, Philip G., additional, Cooper, Cyrus, additional, Cosman, Felicia, additional, Costenbader, Karen H., additional, Creamer, Paul, additional, Crispin, José C., additional, Criswell, Lindsey A., additional, Cronstein, Bruce N., additional, Cross, Raymond, additional, Cusano, Natalie E., additional, Cush, John J., additional, Cutolo, Maurizio, additional, D’Agati, Vivette, additional, Dagfinrud, Hanne, additional, Daikh, David I., additional, Dalton, Seamus E., additional, Dass, Shouvik, additional, David, Jean-Pierre, additional, Davis, Aileen, additional, Deal, Chad L., additional, De Ceulaer, Karel, additional, Deighton, Chris, additional, Dellaripa, Paul F., additional, Rossa, Alessandra Della, additional, Dempster, David, additional, Dennison, Elaine, additional, Denton, Christopher P., additional, Denton, John, additional, Dhawale, Roshan, additional, Doherty, Michael, additional, Dolan, Patricia, additional, Donn, Rachelle, additional, Dooley, Mary Anne, additional, Dougados, Maxime, additional, Drummond, Michael F., additional, Dyer, George S.M., additional, Earp, Brandon E., additional, Edwards, N. Lawrence, additional, Ellender, Patrick, additional, Emery, Paul, additional, Espinoza, Luis R., additional, Farber, Joshua M., additional, Fasth, Anders, additional, Feldman, Debbie, additional, Felson, David T., additional, Fitzgerald, G. Kelley, additional, Flores, Raymond H., additional, Fox, David A., additional, Francomano, Clair A., additional, Freemont, Anthony J., additional, Fresko, Izzet, additional, Fricka, Kevin B., additional, Furst, Daniel E., additional, Gabay, Cem, additional, Gabriel, Sherine E., additional, Galarraga, Bernat, additional, Gäre, Boel Andersson, additional, Garnero, Patrick, additional, Gensler, Lianne S., additional, Gerlag, Danielle M., additional, Geusens, Piet P., additional, Giles, Jon T., additional, Ginzler, Ellen M., additional, Gizinski, Alison M., additional, Gold, Garry, additional, Gonzalez-Rivera, Tania, additional, Gordon, Caroline, additional, Gorodkin, Rachel, additional, Goronzy, Jorg J., additional, Görtz, Simon, additional, Gournelos, Elena, additional, Grahame, Rodney, additional, Grainger, Andrew J., additional, Gravallese, Ellen M., additional, Greenberg, Jeffrey D., additional, Hagley, Karlene, additional, Hakim, Alan J., additional, Hamuryudan, Vedat, additional, Haraoui, Boulos, additional, Harder, Adam, additional, Harley, John B., additional, Harris, E. Nigel, additional, Hashkes, Philip J., additional, Hawker, Gillian, additional, Hawkins, Philip N., additional, Heiberg, Turid, additional, Heinegård, Dick, additional, Helfgott, Simon M., additional, Heller, Jenny E., additional, Herrick, Ariane L., additional, Higgins, Laurence D., additional, Gaston, J. S. Hill, additional, Hochberg, Marc C., additional, Hoffmann, Markus, additional, Holers, V. Michael, additional, Holick, Michael F., additional, Holroyd, Christopher, additional, Hübscher, Osvaldo, additional, Huizinga, Tom W.J., additional, Hunter, David J., additional, Husni, M. Elaine, additional, Inman, Robert D., additional, Isaac, Zacharia, additional, Iversen, Maura D., additional, Jabs, Douglas A., additional, James, Hayley, additional, Javier, Rose-Marie, additional, Jayne, David, additional, Johnsen, Alyssa K., additional, Jordan, Joanne M., additional, Joy, Melanie S., additional, Kaisho, Tsuneyasu, additional, Kallenberg, Cees G.M., additional, Kanno, Yuka, additional, Karlson, Elizabeth W., additional, Kassimos, Dimitrios G., additional, Kastner, Daniel L., additional, Katz, Jeffrey N., additional, Kavanaugh, Arthur, additional, Kay, Jonathan, additional, Kelly, Jennifer A., additional, Keystone, Edward, additional, Khamashta, Munther A., additional, Khanna, Dinesh, additional, Kim, Peter W., additional, Kjeken, Ingvild, additional, Koch, Alisa E., additional, Koff, Matthew F., additional, Kraus, Virginia Byers, additional, Kremers, Hillal Maradit, additional, Krug, Hollis Elaine, additional, Kumar, Pradeep, additional, Kvien, Tore K., additional, Lafyatis, Robert, additional, Landau, Talia, additional, Landewé, Robert B.M., additional, Langford, Carol A., additional, Laxer, Ronald M., additional, Learch, Thomas J., additional, Leirisalo-Repo, Marjatta, additional, Lewith, George T., additional, Li, Yi, additional, Liao, Katherine P., additional, Littlejohn, Geoffrey, additional, Lockshin, Michael D., additional, Lorenzo, Pilar, additional, Luger, Thomas A., additional, Lundberg, Ingrid E., additional, Luthra, Harvinder S., additional, Machold, Klaus P., additional, Mackenzie, C. Ronald, additional, Mahowald, Maren Lawson, additional, Mahr, Alfred D., additional, Marini, Joan C., additional, Markalanda, Eresha, additional, Marquez, Javier, additional, Martel-Pelletier, Johanne, additional, Martin-Mola, Emilio, additional, Martinez-Lavin, Manuel, additional, Massarotti, Elena M., additional, Matteson, Eric L., additional, Mayes, Maureen, additional, Mayosi, Bongani M., additional, McAlindon, Timothy, additional, McCallum, Rex M., additional, McCarthy, Geraldine, additional, McCune, W. Joseph, additional, McGann, Stephany A., additional, McGonagle, Dennis, additional, McLean, Lachy, additional, Mease, Philip J., additional, Merkel, Peter A., additional, Mikdashi, Jamal A., additional, Miller, Frederick W., additional, Miller, Paul D., additional, Minden, Kirsten, additional, Mitsias, Dimitris I., additional, Mody, Girish M., additional, Monach, Paul A., additional, Moreland, Larry W., additional, Moutsopoulos, Haralampos M., additional, Namur, Gauthier, additional, Naredo, Esperanza, additional, Nashel, David J., additional, Nelson, Amanda E., additional, Newman, Stanton P., additional, Nossent, Johannes C., additional, Nöth, Ulrich, additional, O’Connor, Philip, additional, Oddis, Chester V., additional, Olsson, K. Sigvard, additional, Ombrello, Michael J., additional, Orcel, Philippe, additional, O'Shea, John J., additional, Paget, Stephen A., additional, Patrono, Carlo, additional, Pelletier, Jean-Pierre, additional, Pierangeli, Silvia, additional, Pierce, Heather, additional, Pilkington, Clarissa A., additional, Pillinger, Michael H., additional, Pineda, Carlos, additional, Plenge, Robert M., additional, Pricop, Luminita, additional, Rackwitz, Lars, additional, Ramani, Gautam, additional, Ravelli, Angelo, additional, Reeves, Westley H., additional, Remmers, Elaine F., additional, Repo, Heikki, additional, Requena, Luis, additional, Ribbens, Clio, additional, Riley, Graham, additional, Ritchlin, Christopher, additional, Rosas, Ivan O., additional, Roubenoff, Ronenn, additional, Rowan, A.D., additional, Rudwaleit, Martin, additional, Saag, Kenneth G., additional, Salmon, Jane E., additional, Salonen, David C., additional, Salter, Donald M., additional, Salzberg, Daniel J., additional, Sambrook, Philip N., additional, Sanofsky, Benjamin, additional, Saxne, Tore, additional, Schaible, Hans-Georg, additional, Schett, Georg, additional, Schmitz, Nicole, additional, Schon, Lew C., additional, Schumacher, H. Ralph, additional, Scott, David G.I., additional, Seidelmann, Brooke, additional, Sestak, Andrea L., additional, Seton, Margaret, additional, Shadick, Nancy A., additional, Shapiro, Lauren, additional, Shi, Lewis L., additional, Sidiropoulos, Prodromos, additional, Siegel, Richard M., additional, Sieper, Joachim, additional, Silver, Richard M., additional, Silverberg, Shonni J., additional, Simard, Julia F., additional, Simmons, Barry P., additional, Simms, Robert W., additional, Sims, John, additional, Singer, Nora G., additional, Smith, Malcolm D., additional, Smith, Stacy E., additional, Smolen, Josef S., additional, Spector, Tim D., additional, St. Clair, E. William, additional, Steen, Virginia D., additional, Steiner, Günter, additional, Steinert, Andre F., additional, Stone, John H., additional, Stone, Millicent A., additional, Straub, Rainer H., additional, Symmons, Deborah P.M., additional, Szekanecz, Zoltán, additional, Szer, Ilona S., additional, Tak, Paul P., additional, Tavoni, Antonio, additional, Taylor, Peter C., additional, Terkeltaub, Robert, additional, Thabet, Mohamed M., additional, Thorne, Jennifer E., additional, Tsokos, George C., additional, Tuan, Rocky S., additional, Turesson, Carl, additional, Tzioufas, Athanasios G., additional, Uber, Patricia A., additional, van den Berg, Wim B., additional, van der Heijde, Désirée, additional, van Gaalen, Floris A., additional, Varga, John, additional, Vassilopoulos, Dimitrios, additional, Vasudevan, Archana R., additional, Venables, Patrick J.W., additional, Vital, Edward M., additional, Wakefield, Richard J., additional, Walker, Jennifer G., additional, Ward, Robert J., additional, Watts, Richard, additional, Wedderburn, Lucy R., additional, Weinblatt, Michael E., additional, Weir, Matthew R., additional, Wenham, Claire Y.J., additional, West, Sterling G., additional, Weyand, Cornelia M., additional, White, Kenneth E., additional, Williams, Frances M.K., additional, Winthrop, Kevin L., additional, Woolf, Anthony D., additional, Worthington, Jane, additional, Wright, John, additional, Yazici, Hasan, additional, Yazici, Yusuf, additional, York, John R., additional, Young, D.A., additional, Yurdakul, Sebahattin, additional, Zhai, Guangju, additional, Zhang, Yuqing, additional, and Zhuang, Haoyang, additional

Published
2011
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221. Long-term tolerability and efficacy of golimumab in active non-radiographic axial spondyloarthritis: results from open-label extension.

Author

Heijde, Désirée van der, Dougados, Maxime, Maksymowych, Walter P, Bergman, Gina, Curtis, Sean P, Tzontcheva, Anjela, Huyck, Susan, Philip, George, and Sieper, Joachim

Subjects
DRUG efficacy, RANDOMIZED controlled trials, BLIND experiment, STATISTICAL sampling, GOLIMUMAB, PATIENT safety, PHARMACODYNAMICS, EVALUATION
Abstract

Objectives We report the open-label extension (OLE) of the GO-AHEAD study evaluating the long-term efficacy and safety of golimumab (GLM) in patients with non-radiographic axial spondyloarthritis (nr-axSpA). Methods Patients [both GLM- and placebo (PBO)-treated in the double-blind phase] received GLM 50 mg every 4 weeks during the OLE (36-week treatment; additional 8-week safety follow-up; GLM/GLM and PBO/GLM groups). All patients who entered and received ≥1 dose of study treatment in the OLE were included in the efficacy and safety analyses. The primary efficacy evaluations were the proportions of patients achieving 20% and 40% improvement in the ASAS criteria (ASAS20 and ASAS40, respectively). Responders' analyses were calculated using a non-responder imputation approach. Results Of 198 patients randomised, 189/198 (95.5%) entered the OLE; 174/198 patients (87.9%) completed all visits. Although the proportion of responders increased from week 16 to week 52 in the OLE in both GLM/GLM and PBO/GLM groups, the GLM/GLM group had a higher proportion of responders than the PBO/GLM group throughout the OLE from week 16 to week 52 (ASAS20: 71.1% to 83.9% vs 40.0% to 75.0%, respectively; ASAS40: 56.7% to 76.3% vs 23.0% to 59.4%, respectively; ASAS partial remission: 33.0% to 53.8% and 18.0% to 45.8%). In the OLE, the overall incidence of AEs was lower in the GLM/GLM vs PBO/GLM groups (41.9% and 54.2%). Conclusions Sustained improvement in clinical efficacy was observed at 52 weeks in patients with nr-axSpA following GLM treatment. GLM was well tolerated and provided substantial long-term benefits to patients with nr-axSpA. Trial registration NCT01453725; United States National Library of Medicine clinical trials database; www.clinicaltrials.gov. [ABSTRACT FROM AUTHOR]

Published
2022
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222. Safety and Efficacy of Upadacitinib in Patients With Active Ankylosing Spondylitis and an Inadequate Response to Nonsteroidal Antiinflammatory Drug Therapy: One‐Year Results of a Double‐Blind, Placebo‐Controlled Study and Open‐Label Extension

Author

Deodhar, Atul, van der Heijde, Désirée, Sieper, Joachim, Van den Bosch, Filip, Maksymowych, Walter P., Kim, Tae‐Hwan, Kishimoto, Mitsumasa, Ostor, Andrew, Combe, Bernard, Sui, Yunxia, Chu, Alvina D., and Song, In‐Ho

Subjects
ANKYLOSING spondylitis, NONSTEROIDAL anti-inflammatory agents, JANUS kinases, TREATMENT effectiveness, RANDOMIZED controlled trials, BLIND experiment, DESCRIPTIVE statistics, NEUROTRANSMITTER uptake inhibitors, STATISTICAL sampling, ADVERSE health care events, PHARMACODYNAMICS
Abstract

Objective: To report the efficacy and safety of upadacitinib through 1 year in patients with ankylosing spondylitis (AS). Methods: In the SELECT‐AXIS 1 study, adults with active AS and an inadequate response to nonsteroidal antiinflammatory drugs were randomized to receive upadacitinib 15 mg once daily or placebo. At week 14, patients who had been randomized to receive placebo were switched to upadacitinib, and all patients continued in the open‐label extension and received upadacitinib up to week 104; interim data up to week 64 are reported herein. Results: Of 187 patients, 178 completed week 14 on study drug and entered the open‐label extension. Similar proportions of patients in either group (continuous upadacitinib or placebo‐to‐upadacitinib) achieved Assessment of SpondyloArthritis international Society 40% response (ASAS40) or Ankylosing Spondylitis Disease Activity Score (ASDAS) showing low disease activity at week 64: ≥70% of patients achieved these end points based on nonresponder imputation (NRI) and ≥81% based on as‐observed analyses. Furthermore, ≥34% (NRI) and ≥39% (as‐observed analysis) achieved ASDAS showing inactive disease or ASAS showing partial remission at week 64. Mean changes from baseline (week 0) to week 64 in pain, function, and inflammation showed consistent improvement or sustained maintenance through the study. Among 182 patients receiving upadacitinib (237.6 patient‐years), 618 adverse events (260.1 per 100 patient‐years) were reported. No serious infections, major adverse cardiovascular events, venous thromboembolic events, gastrointestinal perforation, or deaths were reported. Conclusion: Upadacitinib 15 mg once daily showed sustained and consistent efficacy over 1 year. Patients who switched from placebo to upadacitinib at week 14 showed similar efficacy versus those who received continuous upadacitinib. [ABSTRACT FROM AUTHOR]

Published
2022
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237. Knochen und Gelenke

Author

Zimmerli, Werner, primary, Herrmann, Mathias, additional, Sieper, Joachim, additional, Heesemann, Jürgen, additional, and Jilg, Wolfgang, additional

Published
2008
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238. Autorinnen und Autoren

Author

Battegay, Manuel, primary, Bauer, Torsten T., additional, Becker, Stephan, additional, Becker, Karsten, additional, Bolz, Michael, additional, Bredt, Wolfgang, additional, Büchler, Markus W., additional, Burchard, Gerd-Dieter, additional, Caspari, Gregor, additional, Cornberg, Markus, additional, Dobner, Thomas, additional, Doerr, Hans W., additional, Domann, Eugen, additional, Drosten, Christian, additional, von Eiff, Christof, additional, Einsele, Hermann, additional, Essig, Andreas, additional, Fegeler, Wolfgang, additional, Fehr, Jan, additional, Friese, Klaus, additional, Gärtner, Barbara C., additional, Gastmeier, Petra, additional, Gatermann, Sören G., additional, Gebhard, Florian, additional, Geffers, Christine, additional, Gerlich, Wolfram H., additional, Glasbrenner, Bernhard, additional, Glück, Thomas, additional, Groß, Uwe, additional, Groschup, Martin, additional, Haase, Gerhard, additional, Hagedorn, Hans-Jochen, additional, Hebart, Holger, additional, Heesemann, Jürgen, additional, Heinz, Werner J., additional, Helbling, Peter, additional, Hengel, Hartmut, additional, Herrmann, Mathias, additional, Heumann, Henning, additional, Hirsch, Hans H., additional, Höffken, Gert, additional, Hörauf, Achim, additional, Itin, Peter, additional, Jilg, Wolfgang, additional, Kandolf, Reinhard, additional, Karrer, Urs, additional, Kaufmann, Stefan H.E., additional, Kern, Peter, additional, Kern, Winfried V., additional, Kist, Manfred, additional, Knaebel, Hanns-Peter, additional, Korn, Klaus, additional, Krause, Karl-Heinz, additional, Krieg, Thomas, additional, Kühn, Joachim, additional, Laifer, Gerd, additional, Lang, Gerhard K., additional, Leidel, Jan, additional, Liesenfeld, Oliver, additional, Löscher, Thomas, additional, Ludolph, Albert C., additional, Männel, Daniela, additional, Manns, Michael P., additional, Marre, Reinhard, additional, Matuschka, Franz-Rainer, additional, Mertens, Thomas, additional, Mettenleiter, Thomas, additional, Michel, Detlef, additional, Morschhäuser, Joachim, additional, von Müller, Lutz, additional, Mylonas, Ioannis, additional, Naber, Kurt G., additional, Neumann-Haefelin, Dieter, additional, Nevels, Michael, additional, Nüesch, Reto, additional, Otto, Markus, additional, Pauli, Georg, additional, Pauschinger, Matthias, additional, Peters, Georg, additional, Pfister, Herbert, additional, von Altishofen, Gabriela Pfyffer, additional, Plachter, Bodo, additional, Podbielski, Andreas, additional, Popow-Kraupp, Therese, additional, Protzer, Ulrike, additional, Reddehase, Matthias J., additional, Rethwilm, Axel, additional, Ritzkowsky, Andreas, additional, Roggenkamp, Andreas, additional, Rudin, Christoph, additional, Rüden, Henning, additional, Schwarz, Carsten, additional, Seiler, Christoph M., additional, Sendi, Parham, additional, Sieper, Joachim, additional, Sigge, Anja, additional, Spellerberg, Barbara, additional, Staib, Peter, additional, Steuerwald, Michael, additional, Strauss, Reinhild, additional, Sunderkötter, Cord Henrich, additional, ter Meulen, Jan, additional, Trautmann, Matthias, additional, Tümmler, Burkhard, additional, Tumani, Hayrettin, additional, Vanek †, Ernst, additional, Veit, Johannes, additional, Vernazza, Pietro, additional, Wagenlehner, Florian, additional, Weidner, Wolfgang, additional, Weinke, Thomas, additional, Weißbrodt, Hartmut, additional, Werner, Jens, additional, Wilske, Bettina, additional, von König, Carl H. Wirsing, additional, and Zimmerli, Werner, additional

Published
2008
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248. Clinical and imaging characteristics of osteitis condensans ilii as compared with axial spondyloarthritis

Author

Poddubnyy, Denis, primary, Weineck, Henning, additional, Diekhoff, Torsten, additional, Redeker, Imke, additional, Gobejishvili, Nino, additional, Llop, Maria, additional, Rodriguez, Valeria Rios, additional, Proft, Fabian, additional, Protopopov, Mikhail, additional, Haibel, Hildrun, additional, Sieper, Joachim, additional, and Hermann, Kay Geert A, additional

Published
2020
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249. Detecting radiographic sacroiliitis using deep learning with expert-level accuracy in axial spondyloarthritis

Author

Bressem, Keno K., primary, Vahldiek, Janis L., additional, Adams, Lisa C., additional, Niehues, Stefan M., additional, Haibel, Hildrun, additional, Rodriguez, Valeria Rios, additional, Torgutalp, Murat, additional, Protopopov, Mikhail, additional, Proft, Fabian, additional, Rademacher, Judith, additional, Sieper, Joachim, additional, Rudwaleit, Martin, additional, Hamm, Bernd, additional, Makowski, Marcus R., additional, Hermann, Kay Geert A., additional, and Poddubnyy, Denis, additional

Published
2020
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250. Central reader evaluation of MRI scans of the sacroiliac joints from the ASAS classification cohort: discrepancies with local readers and impact on the performance of the ASAS criteria

Author

Maksymowych, Walter P, primary, Pedersen, Susanne Juhl, additional, Weber, Ulrich, additional, Baraliakos, Xenofon, additional, Machado, Pedro M, additional, Eshed, Iris, additional, de Hooge, Manouk, additional, Sieper, Joachim, additional, Wichuk, Stephanie, additional, Rudwaleit, Martin, additional, van der Heijde, Désirée, additional, Landewé, Robert B M, additional, Poddubnyy, Denis, additional, Ostergaard, Mikkel, additional, and Lambert, Robert G W, additional

Published
2020
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