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723 results on '"Yamada, Tatsuya"'

220. MIND+ system; More universal dose patterns by single-step ion implantation

Author

Okamoto, Yasuharu, primary, Ninomiya, Shiro, additional, Ochi, Akihiro, additional, Ueno, Yusuke, additional, Yamada, Tatsuya, additional, Kimura, Yasuhiko, additional, Kudo, Tetsuya, additional, Koike, Masazumi, additional, Suetsugu, Noriyuki, additional, Ookita, Yoshiaki, additional, Tsukihara, Mitsukuni, additional, Sato, Fumiaki, additional, Fuse, Genshu, additional, Ueno, Kazuyoshi, additional, and Sugitani, Michiro, additional

Published
2012
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230. Highly reliable high-temperature aluminum sputter metallization

Author

Ogawa Shinichi, Yamada Tatsuya, Robert Sinclair, Hiroshi Nishimura, and Takashi Kouzaki

Subjects
Materials science, Electrical resistance and conductance, Silicon, chemistry, Sputtering, Scanning electron microscope, Transmission electron microscopy, chemistry.chemical_element, Nanotechnology, Substrate (electronics), Sputter deposition, Composite material, Electromigration
Abstract

A highly reliable high-temperature Al-Si-Cu sputter metallization, employing a Ti underlayer to prevent Si from precipitating has been developed, and complete filling of 0.15 micrometers diameter vias with aspect ratio of 4.5 has been achieved. Degree of filling and via chain resistance were improved by increasing the Ti underlayer thickness. This is probably because of improvement in wettability of Al on via sidewall, which is caused by uniform interfacial reaction between Ti underlayers and Al-Si-Cu films. Transmission electron microscopy (TEM) combined with micro energy dispersive spectrometry (EDS) analysis revealed that reacted ball-like precipitates exist at the interface between the first metal and the second metal lines in the filled via, and that the precipitates particles are Al-Ti-Si compounds. No Si precipitation was observed in areas away from or near to the particles. Also, it was found that Al films in the vias consist of one or two single crystalline textured normal to a substrate. The electrical resistance for the 0.3 micrometers sputter filled via was 0.71 (Omega) , which is about one order of magnitude lower than that for a non-filled (conventional) via. The electromigration (EM) resistance of 0.3 micrometers filled vias was found to be four orders of magnitude greater than that for the 0.3 micrometers conventional vias. Furthermore, we confirmed that the EM resistance for the 0.3 micrometers filled via is comparable to the 0.9 micrometers conventional via. Superior EM and stress-induced migration (SM) resistance for the lines have been confirmed.© (1993) COPYRIGHT SPIE--The International Society for Optical Engineering. Downloading of the abstract is permitted for personal use only.

Published
1993

234. CO2 sequestration into hydrothermal system at Ogachi HDR site

Author

UEDA, Akira, primary, KURODA, Yoshihiro, additional, YAMADA, Tatsuya, additional, KATO, Kouichi, additional, YAJIMA, Tatsuya, additional, SATOH, Hisao, additional, SUGIYAMA, Kazutoshi, additional, OZAWA, Akiko, additional, ODASHIMA, Yoshitsugu, additional, KAIEDA, Hideshi, additional, ITO, Hisatoshi, additional, KUBOTA, Kenji, additional, TODAKA, Norifumi, additional, AJIMA, Shuji, additional, SATO, Tatsuya, additional, KAJI, Yoshikazu, additional, OHSUMI, Takashi, additional, WAKAHAMA, Hiroshi, additional, and MITO, Saeko, additional

Published
2009
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239. Prognostic significance of BMP and activin membranebound inhibitor in colorectal cancer

Author

Togo, Nozomi, primary, Ohwada, Susumu, additional, Sakurai, Shinji, additional, Toya, Hiroyuki, additional, Sakamoto, Ichiro, additional, Yamada, Tatsuya, additional, Nakano, Tetsuhiro, additional, Muroya, Ken, additional, Takeyoshi, Izumi, additional, Nakajima, Takashi, additional, Sekiya, Takashi, additional, Yamazumi, Yusuke, additional, Nakamura, Tsutomu, additional, and Akiyama, Tetsu, additional

Published
2008
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246. Nicorandil decreases cardiac events during and after noncardiac surgery

Author

Kashimoto, Satoshi, primary, Seki, Makoto, additional, Ishiguro, Toshihiko, additional, Yoshioka, Hitoshi, additional, Nagata, Osamu, additional, Nishimura, Kinya, additional, Kikuchi, Toshihiro, additional, Yamada, Tatsuya, additional, Iwade, Motoyo, additional, Omi, Akibumi, additional, Honda, Osamu, additional, Sakamoto, Atsuhiro, additional, Ogihara, Yukihiko, additional, Fujimoto, Keiko, additional, Nakaigawa, Yasushi, additional, Kato, Jitsu, additional, Watanabe, Akio, additional, Nomura, Minoru, additional, and Takeda, Junzo, additional

Published
2007
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249. Curcumin treatment enhances the effect of exercise on mitochondrial biogenesis in skeletal muscle by increasing cAMP levels.

Author

Ray Hamidie, Ronald D., Yamada, Tatsuya, Ishizawa, Rie, Saito, Yoko, and Masuda, Kazumi

Subjects
CURCUMIN, EXERCISE physiology, MITOCHONDRIA formation, SKELETAL muscle, POLYPHENOLS, THERAPEUTICS
Abstract

Background In response to physiologic stressors, skeletal muscle has the potential to elicit wide variety of adaptive responses, such as biogenesis of mitochondria and clearance of damaged mitochondria to promote healthy muscle. The polyphenol curcumin, derived from the rhizome Curcuma longa L ., is a natural antioxidant that exhibits various pharmacological activities and therapeutic properties. However, the effect of curcumin on the regulation of mitochondrial biogenesis in skeletal muscle remains unknown. The present study aimed to examine the effects of combination of endurance training (eTR) and curcumin treatment on the expression of AMPK, SIRT1, PGC-1α, and OXPHOS subunits, mitochondrial DNA copy number, and CS activity in rat skeletal muscle. Furthermore, the present study also examined the effect of exercise and curcumin treatment on the levels of cAMP and downstream targets of PKA including phosphorylated CREB and LKB-1. Methods Ten-week-old male Wistar rats were randomly divided into non-eTR and eTR groups. Low doses (50 mg/kg-BW/day) or high doses (100 mg/kg-BW/day) of curcumin dissolved in dimethyl sulfoxide (DMSO) were injected intraperitoneally in all animals for 28 days to investigate the effect of curcumin alone and the combined effect of curcumin with eTR. Western blotting (WB) and immunoprecipitation (IP) were performed to detect the presence of proteins. Results Our results demonstrated that combination of curcumin treatment and eTR increased the expression of COX-IV, OXPHOS subunits, mitochondrial DNA copy number and CS activity in the gastrocnemius (Gas) and soleus (Sol) muscles. In addition, this combination increased AMPK phosphorylation, NAD + /NADH ratio, SIRT1 expression, and PGC-1α deacetylation. Furthermore, curcumin treatment as well as exercise also increased levels of cAMP and downstream target of PKA including phosphorylation CREB and LKB-1 which are involved in the regulation of mitochondrial biogenesis. Conclusion Taken together, these results suggest that the combination of curcumin treatment and eTR has the potential to accelerate mitochondrial biogenesis in skeletal muscle by increasing cAMP levels. [ABSTRACT FROM AUTHOR]

Published
2015
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