514 results on '"Gil, Santiago"'
Search Results
252. Design Criteria for Full Passive Long Range UHF RFID Sensor for Human Body Temperature Monitoring
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Pardo, Daniel, primary, Vaz, Alexander, additional, Gil, Santiago, additional, Gomez, Josean, additional, Ubarretxena, Aritz, additional, Puente, David, additional, Morales-Ramos, Ricardo, additional, Garcia-Alonso, Andres, additional, and Berenguer, Roc, additional
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- 2007
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253. Interobserver variance in myelodysplastic syndromes with less than 5 % bone marrow blasts: unilineage vs. multilineage dysplasia and reproducibility of the threshold of 2 % blasts.
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Font, Patricia, Loscertales, Javier, Soto, Carlos, Ricard, Pilar, Novas, Carolina, Martín-Clavero, Estela, López-Rubio, Montserrat, Garcia-Alonso, Luis, Callejas, Marta, Bermejo, Alfredo, Benavente, Celina, Ballesteros, Mónica, Cedena, Teresa, Calbacho, María, Urbina, Raquel, Villarrubia, Jesús, Gil, Santiago, Bellón, José, Diez-Martin, José, and Villegas, Ana
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MYELODYSPLASTIC syndromes ,BONE marrow ,DYSPLASIA ,REFRACTORY anemia ,PROGENITOR cells ,CYTOGENETICS ,DIAGNOSIS - Abstract
Previous studies have shown the reproducibility of the 2008 World Health Organization (WHO) classification in myelodysplastic syndromes (MDS), especially when multilineage dysplasia or excess of blasts are present. However, there are few data regarding the reproducibility of MDS with unilineage dysplasia. The revised International Prognostic Scoring System R-IPSS described two new morphological categories, distinguishing bone marrow (BM) blast cell count between 0-2 % and >2- < 5 %. This distinction is critical for establishing prognosis, but the reproducibility of this threshold is still not demonstrated. The objectives of our study were to explore the reliability of the 2008 WHO classification, regarding unilineage vs. multilineage dysplasia, by reviewing 110 cases previously diagnosed with MDS, and to study whether the threshold of ≤2 % BM blasts is reproducible among different observers. We used the same methodology as in our previous paper [Font et al. (2013) Ann Hematol 92:19-24], by encouraging investigators to include patients with <5 % BM blasts. Samples were collected from 11 hospitals and were evaluated by 11 morphologists. Each observer evaluated 20 samples, and each sample was analyzed independently by two morphologists. Discordance was observed in 36/108 suitable cases (33 %, kappa test 0.503). Diagnosis of MDS with unilineage dysplasia (refractory cytopenia with unilineage dysplasia (RCUD), refractory anemia with ring sideroblasts (RARS) or unclassifiable MDS) was assessed in 33 patients, by either of the two observers. We combined this series with the cases with RCUD or RARS included in our 2013 paper, thus obtaining 50 cases with unilineage dysplasia by at least one of the observers. The whole series showed very low agreement regarding RCUD (5/23, 21 %) and RARS (5/28, 18 %). Regarding BM blast count, the threshold of ≤2 % was not reproducible (discordance rate 32/108 cases, kappa test 0.277). Our study shows that among MDS WHO 2008 categories, interobserver discordance seems to be high in cases with unilineage dysplasia. We also illustrate that the threshold of ≤2 % BM blasts as settled by the R-IPSS may be not easy to reproduce by morphologists in real practice. [ABSTRACT FROM AUTHOR]
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- 2015
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254. Opinion spreading and agent segregation on evolving networks
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Zanette, Damián H., primary and Gil, Santiago, additional
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- 2006
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255. Coevolution of agents and networks: Opinion spreading and community disconnection
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Gil, Santiago, primary and Zanette, Damián H., additional
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- 2006
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256. Confirmacions d'una realitat: Antoni Viladomat i Manalt
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Alcolea i Gil, Santiago
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- 1990
257. Post-Engraftment Infections in Adult Patients Transplanted with Single Cord Blood Units Supported by Co-Infusion of Mobilized Purified Hematopoietic Stem Cells from a Third Party Donor.
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Cabrera, J. Rafael, primary, Krsnik, Isabel, primary, Fores, Rafael, primary, Ruiz, Elena, primary, Bautista, Guiomar, primary, Navarro, Belen, primary, Gayoso, Jorge, primary, Gil, Santiago, primary, Regidor, Carmen, primary, Sanjuan, Isabel, primary, Ojeda, Emilio, primary, Garcia-Marco, Jose A., primary, and Fernandez, Manuel N., primary
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- 2005
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258. Unrelated Single Cord Blood Transplant Supported by Co-Infusion of a Low Number of Mobilized Peripheral Blood Highly Purified CD34+ Cells from a Third Party Donor after Low Toxicity Myeloablative Conditioning. a Strategy That Makes Cord Blood Transplant Feasible for Most Patients. (An “Allostem” Study).
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Fernandez, Manuel N., primary, Regidor, Carmen, additional, Cabrera, Rafael, additional, Magro, Elena, additional, Fores, Rafael, additional, Bautista, Guiomar, additional, Gayoso, Jorge, additional, Ruiz, Elena, additional, Navaro, Belen, additional, Gil, Santiago, additional, Sanjuan, Isabel, additional, and Garcia-Marco, Jose A., additional
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- 2004
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259. DIU con levonorgestrel comparable a la histerectomía para tratar la hipermenorrea
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Gil, Santiago, primary
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- 2004
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260. Unrelated umbilical cord blood transplants in adults: Early recoveryof neutrophils by supportive co-transplantation of a low number of highlypurified peripheral blood CD34+ cells from an HLA-haploidentical donor
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Fernández, Manuel N, primary, Regidor, Carmen, additional, Cabrera, Rafael, additional, Garcı́a-Marco, José A, additional, Forés, Rafael, additional, Sanjuán, Isabel, additional, Gayoso, Jorge, additional, Gil, Santiago, additional, Ruı́z, Elena, additional, Little, Ann-Margaret, additional, McWhinnie, Alasdair, additional, and Madrigal, Alejandro, additional
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- 2003
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261. Casos En Imagen: 1
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de la Hoz, Javier, primary, Alonso, Sergio, additional, and Gil, Santiago, additional
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- 2001
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262. Effectiveness and Safety of Balloon Dilation of the Papilla and the Use of an Occlusion Balloon for Clearance of Bile Duct Calculi
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Gil, Santiago, primary, de la Iglesia, Pedro, additional, Verdú, José F., additional, de España, Francisco, additional, Arenas, Juan, additional, and Irurzun, Javier, additional
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- 2000
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263. Validation of the Determinant-based Classification and Revision of the Atlanta Classification Systems for Acute Pancreatitis.
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Acevedo–Piedra, Nelly G., Moya–Hoyo, Neftalí, Rey–Riveiro, Mónica, Gil, Santiago, Sempere, Laura, Martínez, Juan, Lluís, Félix, Sánchez–Payá, José, and de–Madaria, Enrique
- Abstract
Background & Aims: Two new classification systems for the severity of acute pancreatitis (AP) have been proposed, the determinant-based classification (DBC) and a revision of the Atlanta classification (RAC). Our aim was to validate and compare these classification systems. Methods: We analyzed data from adult patients with AP (543 episodes of AP in 459 patients) who were admitted to Hospital General Universitario de Alicante from December 2007 to February 2013. Imaging results were reviewed, and the classification systems were validated and compared in terms of outcomes. Results: Pancreatic necrosis was present in 66 of the patients (12%), peripancreatic necrosis in 109 (20%), walled-off necrosis in 61 (11%), acute peripancreatic fluid collections in 98 (18%), and pseudocysts in 19 (4%). Transient and persistent organ failures were present in 31 patients (6%) and 21 patients (4%), respectively. Sixteen patients (3%) died. On the basis of the DBC, 386 (71%), 131 (24%), 23 (4%), and 3 (0.6%) patients were determined to have mild, moderate, severe, or critical AP, respectively. On the basis of the RAC, 363 patients (67%), 160 patients (30%), and 20 patients (4%) were determined to have mild, moderately severe, or severe AP, respectively. The different categories of severity for each classification system were associated with statistically significant and clinically relevant differences in length of hospital stay, need for admission to the intensive care unit, nutritional support, invasive treatment, and in-hospital mortality. In comparing similar categories between the classification systems, no significant differences were found. Conclusion: The DBC and the RAC accurately classify the severity of AP in subgroups of patients. [Copyright &y& Elsevier]
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- 2014
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264. Myelodysplastic syndrome: a search for minimal diagnostic criteria
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Ramos, Fernando, primary, Fernández-Ferrero, Silvia, additional, Suárez, Dimas, additional, Barbón, Marcos, additional, Rodrı́guez, José Antonio, additional, Gil, Santiago, additional, Megido, Marta, additional, Ciudad, Juana, additional, López, Natalia, additional, del Cañizo, Consuelo, additional, and Orfao, Alberto, additional
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- 1999
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265. Excavaciones paleontológicas en Zamora: La cuesta del Viso
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Jiménez Fuentes, Emiliano, Gil, Santiago, Ortega, Francisco Javier, Jiménez Fuentes, Emiliano, Gil, Santiago, and Ortega, Francisco Javier
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- 1993
266. EMERGENCE OF COOPERATION IN A MODEL FOR AGRICULTURAL PRODUCTION.
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Gil, Santiago and Serrat-Capdevila, Aleix
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AGRICULTURAL productivity , *AGRICULTURE , *AGRICULTURAL water supply , *SOWING , *COOPERATION - Abstract
The emergence of cooperation in a model for an artificial farming society is studied here by the use of an agent-based model. The system is composed of an ensemble of N agents assumed to have equal access to water, whose availability fluctuates randomly in time. Each agent makes two decisions every sowing season regarding: (1) the type of crop mix to plant and (2) whether s/he joins, or not, a cooperative group that allocates water amongst farmers to maximize the production and share revenues equally. Results show that the degree to which farmers choose to cooperate has a strong dependency on the mean water availability. Cooperation seems to emerge as a way of adaptation to uncertain environments by which individual risk is minimized. [ABSTRACT FROM AUTHOR]
- Published
- 2010
267. Results of a pilot study on the use of third-party donor mesenchymal stromal cells in cord blood transplantation in adults.
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Gonzalo-Daganzo, Rosa, Regidor, Carmen, Martin-Donaire, Trinidad, Rico, Miguel Angel, Bautista, Guiomar, Krsnik, Isabel, Fores, Rafael, Ojeda, Emilio, Sanjuan, Isabel, Garcia-Marco, Jose A., Navarro, Belen, Gil, Santiago, Sanchez, Rocio, Panadero, Nuria, Gutierrez, Yolanda, Garcia-Berciano, Miguel, Perez, Nuria, Millan, Isabel, Cabrera, Rafael, and Fernandez, Manuel N.
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BLOOD donors ,MESENCHYME ,CORD blood transplantation ,GRAFT versus host disease ,HEMATOPOIETIC stem cells ,NEUTROPHILS ,CLINICAL medicine research - Abstract
Background aims Cord blood (CB) transplants with co-infusion of third-party donor (TPD) mobilized hematopoietic stem cells (MHSC) have been shown to result in 'bridge' engraftment with prompt neutrophil recovery and high final rates of CB engraftment and full chimerism. This strategy overcomes the limitation posed by low cellularity of CB units for unrelated transplants in adults. Enhancement of adaptive immunity reconstitution without increasing risks of graft-versus-host disease (GvHD) is required to optimize results further. Our objectives were to evaluate co-infusion of mesenchymal stromal cells (MSC) from the same TPD regarding tolerance, CB engraftment and effects on acute (a)GvHD, both preventive and therapeutic. Methods Ex vivo-expanded bone marrow MSC were infused at the time of the transplant or the in case of refractory aGvHD. Results Nine patients received 1.04-2.15×106/kg (median 1.20) MSC immediately after CB and TPD MHSC. Neither immediate adverse side-effects nor significant differences regarding CB engraftment or aGvHD development were observed. Four patients developed grade II aGvHD, refractory to steroids in two. These reached complete remission after therapeutic infusions of MSC. Conclusions In recipients of 'dual CB/TPD MHSC transplants', MSC infusions were therapeutically effective for severe aGvHD but no significant differences in CB engraftment and incidence of severe aGvHD were observed following their prophylactic use. Although results of this study alone cannot conclusively determine the application of MSC in CB transplantation, we believe that, in this setting, the best use of MSC could be as pre-emptive treatment for aGvHD. [ABSTRACT FROM AUTHOR]
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- 2009
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268. Usefulness of surveillance programmes for early diagnosis of hepatocellular carcinoma in clinical practice.
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Pascual, Sonia, Irurzun, Javier, Zapater, Pedro, Such, Jos, Sempere, Laura, Carnicer, Fernando, Palazón, Jose María, de la Iglesia, Pedro, Gil, Santiago, de España, Francisco, and Perez-Mateo, Miguel
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LIVER cancer ,THERAPEUTICS ,MULTIVARIATE analysis ,CONFIDENCE intervals ,DIAGNOSIS - Abstract
Background/Aims: Surveillance programmes (SPs) for hepatocellular carcinoma (HCC) in patients with cirrhosis intend to diagnose the tumour in its early stages when an effective therapy can be applied. The aims of this study have been to compare the survival of patients with HCC being diagnosed or not in SPs, and to establish a more accurate profile of the best target population. Methods: From January 1996 to June 2005, 290 patients with HCC were included. The relationship between being diagnosed or not in an SP and survival has been analysed in a univariate analysis. Pretreatment variables found to be significant predictors of survival in univariate analysis were included in a multivariate analysis. Results: The mean survival for patients diagnosed in SPs (27 months, 16.6–37.4) was significantly longer than in patients being diagnosed out of these programmes (6 months, 2.6–9.4) ( P=0.001). Child–Pugh class A [β 1.4, 95% confidence interval (CI) 1.14–1.78; P=0.0002] and being diagnosed in SPs (β 0.4, 95% CI 0.3–0.6; P=0.0003) became the only independent predictive factors of longer survival. Conclusions: SPs for HCC allow the detection of small tumours and the application of intention-to-cure therapies, which improves survival. However, these programmes do not improve prognosis in patients with advanced cirrhosis. [ABSTRACT FROM AUTHOR]
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- 2008
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269. Manejo de la persona en huelga de hambre en Atención Primaria: protocolo de actuación.
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Gil Santiago, Ayoze and Fernández Nakoura, Dulce
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- 2018
270. Cognición social en pacientes con esquizofrenia, familiares de primer grado y controles sanos. Comparación entre grupos y análisis de variables clínicas y sociodemográficas relacionadas.
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Rodríguez Sosa, Juana Teresa, Gil Santiago, Hiurma, Trujillo Cubas, Angel, Winter Navarro, Marta, León Pérez, Petra, Guerra Cazorla, Luz Marina, and Martín Jiménez, José María
- Abstract
Resumen: Objetivo: Evaluar y comparar la cognición social en pacientes con esquizofrenia, familiares de primer grado y controles sanos. Estudiar la relación que guarda la cognición social con la cognición no social, la psicopatología y otras variables clínicas y sociodemográficas. Método: La muestra total la formaron pacientes diagnosticados de esquizofrenia paranoide (n=29), familiares sanos de primer grado (n=21) y controles (n=28). Todos los grupos fueron evaluados con un cuestionario ad hoc y la Escala de Cognición Social que evalúa los dominios: procesamiento emocional, percepción social y estilo atribucional en la población española. El grupo de pacientes fue evaluado también con la Escala para el Síndrome Positivo y Negativo de la Esquizofrenia y el Mini-Examen Cognoscitivo. Los datos fueron analizados con el paquete estadístico SPSS versión 15.0. Resultados: Los pacientes puntuaron significativamente peor en todos los dominios de la cognición social evaluados en comparación con los controles y en el dominio estilo atribucional en comparación con los familiares. El tipo de psicopatología correlacionó de forma negativa y estadísticamente significativa con dominios diferentes de la cognición social: la sintomatología negativa con el procesamiento emocional y el estilo atribucional y la sintomatología positiva con la percepción social. Las puntuaciones en la cognición básica correlacionaron de forma positiva y estadísticamente significativa con los dominios percepción social y estilo atribucional. Conclusión: La cognición social se ha convertido en un interesante objeto de estudio, especialmente por la relación que guarda con la cognición no social, la psicopatología y el funcionamiento global de los pacientes, aportando nuevos elementos a considerar en la detección precoz, el tratamiento integral y la rehabilitación psicosocial de los pacientes. Su conceptualización como variable de rasgo y la consideración de la existencia de un continuum entre pacientes y familiares son hipótesis plausibles que requieren mayor investigación. [Copyright &y& Elsevier]
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- 2013
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271. Visceral leishmaniasis in hematopoietic stem cell transplantation.
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Bautista, Guiomar, Ramos, Antonio, and Gil, Santiago
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LETTERS to the editor ,VISCERAL leishmaniasis ,HEMATOPOIETIC stem cell transplantation - Abstract
A letter to the editor is presented regarding the case study of a 60-year-old man diagnosed with visceral leishmaniasis (VL) following hematopoietic stem cell transplantation.
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- 2012
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272. Structural and mechanistic insights into the substrate specificity and hydrolysis of GH31 α-N-acetylgalactosaminidase.
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Miyazaki, Takatsugu, Ikegaya, Marina, and Alonso-Gil, Santiago
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GLUCOSIDASES , *PEPTIDES , *HYDROLYSIS , *QUANTUM mechanics , *ALPHA fetoproteins , *ENTEROCOCCUS faecalis - Abstract
Glycoside hydrolase family 31 (GH31) is a diversified family of anomer-retaining α-glycoside hydrolases, such as α-glucosidase and α-xylosidase, among others. Recently, GH31 α- N -acetylgalactosaminidases (Nag31s) have been identified to hydrolyze the core of mucin-type O -glycans and the crystal structure of a gut bacterium Enterococcus faecalis Nag31 has been reported. However, the mechanisms of substrate specificity and hydrolysis of Nag31s are not well investigated. Herein, we show that E. faecalis Nag31 has the ability to release N -acetylgalactosamine (GalNAc) from O -glycoproteins, such as fetuin and mucin, but has low activity against Tn antigen. Mutational analysis and crystal structures of the Michaelis complexes reveal that residues of the active site work in concert with their conformational changes to act on only α- N -acetylgalactosaminides. Docking simulations using GalNAc-attached peptides suggest that the enzyme mainly recognizes GalNAc and side chains of Ser/Thr, but not strictly other peptide residues. Moreover, quantum mechanics calculations indicate that the enzyme preferred p -nitrophenyl α- N -acetylgalactosaminide to Tn antigen and that the hydrolysis progresses through a conformational itinerary, 4 C 1 → 1 S 3 → 4 C 1 , in GalNAc of substrates. Our results provide novel insights into the diversification of the sugar recognition and hydrolytic mechanisms of GH31 enzymes. [Display omitted] • EfGH31 released N -acetylgalactosamine from fetuin and bovine submaxillary mucin. • Crystal structures of EfGH31 complexed with substrates were determined. • The active site residues important for hydrolysis and substrate-binding were identified. • QM calculation revealed its conformational itinerary and reactivity. [ABSTRACT FROM AUTHOR]
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- 2022
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273. Cuando llegue el momento sólo conservarás en tu memoria.
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Gil, Santiago
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- 2020
274. Els retaules catalans a l'època barroca: les aportacions manresanes
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Alcolea i Gil, Santiago
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- 1989
275. La façana de l'església de Santa Maria de Mataró
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Alcolea i Gil, Santiago
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- 1984
276. From Ethanolamine Precursor Towards ZnO—How N Is Released from the Experimental and Theoretical Points of View.
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Gómez-Núñez, Alberto, Alonso-Gil, Santiago, López, Concepción, Roura-Grabulosa, Pere, and Vilà, Anna
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MOLECULAR dynamics , *SCISSION (Chemistry) , *LIGANDS (Chemistry) , *ZINC oxide synthesis , *ORGANOPLATINUM compounds , *ACETATES , *ZINC oxide - Abstract
This work presents experimental and computational studies on ZnO formation after decomposition of a sol-gel precursor containing ethanolamine and Zn(II) acetate. The structural modifications suffered during decomposition of the monomeric and dimeric Zn(II) complexes formed, containing bidentate deprotonated ethanolamine and acetato ligands, have been described experimentally and explained via Car-Parrinello Molecular Dynamics. Additional metadynamics simulations provide an overview of the dimer evolution by the cleavage of the Zn–N bond, the structural changes produced and their effects on the Zn(II) environment. The results provide conclusive evidence of the relevance of ethanolamine used as a stabilizer in the formation of ZnO. [ABSTRACT FROM AUTHOR]
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- 2019
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277. Vitalidad artística del Camino de Santiago en el siglo XVI
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Alcolea Gil, Santiago and Alcolea Gil, Santiago
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- 1964
278. Observational constraints on the age-metallicity relation from white dwarf-Main sequence binaries
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Rebassa Mansergas, Alberto, García-Berro Montilla, Enrique, Torres Gil, Santiago, Anguiano, B., Manser, C. J., Gänsicke, Boris T., Liu, X., Universitat Politècnica de Catalunya. Departament de Física, and Universitat Politècnica de Catalunya. GAA - Grup d'Astronomia i Astrofísica
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Física::Astronomia i astrofísica [Àrees temàtiques de la UPC] ,Astrophysics::Solar and Stellar Astrophysics ,Astrophysics::Earth and Planetary Astrophysics ,Astrophysics::Cosmology and Extragalactic Astrophysics ,Estels nans ,Astrophysics::Galaxy Astrophysics ,White dwarfs stars - Abstract
The age-metallicity relation (AMR) is a fundamental observational property to understand how the Galactic disc formed and evolved chemically in time. However, there is not yet a consensus on the observed properties of the AMR for the solar neighbourhood. This is due primarily to the difficulty of obtaining precise stellar ages for individual field stars. We have started an observational campaign to provide the much needed observational AMR by using white dwarf-main sequence (WDMS) binaries. White dwarfs are natural clocks and can be used to derive accurate ages. Metallicities can be obtained from the main sequence companions. Since white dwarfs and main sequence stars in these binary systems are coeval, these binaries provide an unique opportunity to observationally determine in a robust way the AMR. Here we present the AMR derived from the analysis of a sample of 23 WDMS binaries
279. A population synthesis study of the MS+WD population in the SDSS
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García-Berro Montilla, Enrique|||0000-0002-1623-5838, Torres Gil, Santiago|||0000-0001-5777-5251, Camacho Díaz, Judit|||0000-0003-2322-2098, Rebassa Mansergas, Alberto|||0000-0002-6153-7173, Gänsicke, Boris T., Schreiber, Mathias R., Zorotovic, Mónica, Universitat Politècnica de Catalunya. Departament de Física, and Universitat Politècnica de Catalunya. GAA - Grup d'Astronomia i Astrofísica
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stellar evolution ,Física::Astronomia i astrofísica [Àrees temàtiques de la UPC] ,education ,Astrophysics::Solar and Stellar Astrophysics ,White dwarfs ,Estels nans ,White dwarf stars ,Monte Carlo simulation - Abstract
Detached white dwarf + main sequence (WD+MS) systems represent the simplest population of post-common envelope binaries (PCEBs), and their ensemble properties carry important information about common-envelope phase. However, most population synthesis studies do not fully consider the effects of the observational selection biases of the samples used to compare with the theoretical simulations. We present a set of detailed Monte Carlo simulations of the population of WD+MS binaries in the Sloan Digital Sky Survey (SDSS) Data Release 7, which allows us to make a sound comparison with the available observed data. We find that our simulations correctly reproduce the properties of the observed distribution of WD+MS PCEBs. This includes the distribution of orbital periods and of masses of the white dwarf and main sequence stars. These distributions can be correctly reproduced for several choices of the free parameters, although models in which = 10% of the internal energy is used to eject the common envelope, and in which a small common envelope efficiency = 0.3 seem to fit the observational data better. We also find that systems with He-core white dwarfs are over-represented in the observed sample, because of selection effects.
280. Monte Carlo simulations of the post-common envelope white dwarf-main sequence binary population
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Camacho Díaz, Judit, Torres Gil, Santiago, García-Berro Montilla, Enrique, Zorotovic, Monica, Schreiber, Mathias R., Universitat Politècnica de Catalunya. Departament de Física Aplicada, and Universitat Politècnica de Catalunya. GAA - Grup d'Astronomia i Astrofísica
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Multiple imputation (Statistics) ,Física::Astronomia i astrofísica::Cosmologia i cosmogonia [Àrees temàtiques de la UPC] ,White dwarf stars ,Estels
281. Monte Carlo simulations of the formation channels of SNeIb. PoS(SUPERNOVA)008
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Camacho Díaz, Judit, Torres Gil, Santiago, García-Berro Montilla, Enrique, Universitat Politècnica de Catalunya. Departament de Física Aplicada, and Universitat Politècnica de Catalunya. GAA - Grup d'Astronomia i Astrofísica
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Double stars ,Supernoves ,Física::Astronomia i astrofísica [Àrees temàtiques de la UPC] ,Astrophysics::Solar and Stellar Astrophysics ,Astrophysics::Cosmology and Extragalactic Astrophysics ,Astrophysics::Earth and Planetary Astrophysics ,Astrophysics::Galaxy Astrophysics - Abstract
We present a Monte Carlo simulator of the population of binary stars within the solar neighborhood. We have used the most updated models for stellar evolution, a complete treatment of the Roche lobe over ow episodes, as well as a full implementation of the orbital evolution. Special emphasis has been placed on processes leading to the formation of binary systems in which one of the members is a white dwarf. As a preliminary application of our Monte Carlo simulator we have performed a statistical study of the scenarios leading to type Ib supernovae events within our Galaxy
282. Carta pastoral que el Ilmo. señor obispo de Lugo dirige al Clero y pueblo de su diócesi con motivo del Jubileo concedido por ... el Papa Pio IX en ... agosto de 1854
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Lugo (Diócese). Bispo (1847-1857 : Santiago Rodríguez Gil), Rodríguez Gil, Santiago , Bispo de Lugo, Imprenta de Pujol y Hermano (Lugo), Lugo (Diócese). Bispo (1847-1857 : Santiago Rodríguez Gil), Rodríguez Gil, Santiago , Bispo de Lugo, and Imprenta de Pujol y Hermano (Lugo)
- Abstract
Convenio RAG, O bispo de lugo é Santiago Rodríguez Gil
283. Explaining the Type Ia supernova PTF 11kx with a violent prompt merger scenario
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Universitat Politècnica de Catalunya. Departament de Física Aplicada, Universitat Politècnica de Catalunya. GAA - Grup d'Astronomia i Astrofísica, García-Berro Montilla, Enrique, Torres Gil, Santiago, Camacho Díaz, Judit, Soker, Noam, Kashi, Amit, Universitat Politècnica de Catalunya. Departament de Física Aplicada, Universitat Politècnica de Catalunya. GAA - Grup d'Astronomia i Astrofísica, García-Berro Montilla, Enrique, Torres Gil, Santiago, Camacho Díaz, Judit, Soker, Noam, and Kashi, Amit
- Abstract
We argue that the multiple shells of circumstellar material (CSM) and the supernovae (SNe) ejecta interaction with the CSM starting 59 d after the explosion of the Type Ia SN PTF 11kx are best described by a violent prompt merger. In this prompt merger scenario, the common envelope (CE) phase is terminated by a merger of a white dwarf (WD) companion with the hot core of a massive asymptotic giant branch star. In most cases, the WD is disrupted and accreted on to the more massive core. However, in the rare cases, where the merger takes place when the WD is denser than the core, the core will be disrupted and accreted on to the cooler WD. In such cases, the explosion might occur with no appreciable delay, i.e. months to years after the termination of the CE phase. This, we propose, might be the evolutionary route that could lead to the explosion of PTF 11kx. This scenario can account for the very massive CSM within similar to 1000 au of the exploding PTF 11kx star, for the presence of hydrogen, and for the presence of shells in the CSM., Peer Reviewed, Postprint (published version)
284. The effects of metallicity on the Galactic disk population of white dwarfs
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Universitat Politècnica de Catalunya. Departament de Física Aplicada, Universitat Politècnica de Catalunya. GAA - Grup d'Astronomia i Astrofísica, Cojocaru, Elena Ruxandra, Torres Gil, Santiago, Isern Vilaboy, Jordi, García-Berro Montilla, Enrique, Universitat Politècnica de Catalunya. Departament de Física Aplicada, Universitat Politècnica de Catalunya. GAA - Grup d'Astronomia i Astrofísica, Cojocaru, Elena Ruxandra, Torres Gil, Santiago, Isern Vilaboy, Jordi, and García-Berro Montilla, Enrique
- Abstract
Context. It has been known for a long time that stellar metallicity plays a significant role in the determination of the ages of the different Galactic stellar populations, when main sequence evolutionary tracks are employed. Aims. Here, we analyze the role that metallicity plays on the white dwarf luminosity function of the Galactic disk, which is often used to determine its age. Methods. We employ a Monte Carlo population synthesis code that accounts for the properties of the population of Galactic disk white dwarfs. Our code incorporates the most up-to-date evolutionary cooling sequences for white dwarfs with hydrogen-rich and hydrogen-deficient atmospheres for both carbon-oxygen and oxygen-neon cores. We use two different models to assess the evolution of the metallicity: the first, where the adopted metallicity is constant with time but with a moderate dispersion, and the second where the metallicity increases with time. Results. We found that our theoretical results are in a very satisfactory agreement with the observational luminosity functions obtained from the Sloan Digital Sky Survey (SDSS) and from the SuperCOSMOS Sky Survey (SSS). These results are independent of the adopted age-metallicity law. In particular, we found that the age-metallicity law has no noticeable impact in shaping the bright branch of the white dwarf luminosity function and that the position of its cut-off is almost insensitive to the adopted age-metallicity relationship. Conclusions. Because the shape of the bright branch of the white dwarf luminosity function is insensitive to the age-metallicity law, it can be safely employed to test the theoretical evolutionary sequences, while its location provides a robust indicator of the age of the Galactic disk due to the limited sensitivity of the position of the drop-off to the distribution of metallicities, Postprint (published version)
285. Carta pastoral que el Ilmo. señor obispo de Lugo dirige al Clero y pueblo de su diócesi con motivo del Jubileo concedido por ... el Papa Pio IX en ... agosto de 1854
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Lugo (Diócese). Bispo (1847-1857 : Santiago Rodríguez Gil), Rodríguez Gil, Santiago , Bispo de Lugo, Imprenta de Pujol y Hermano (Lugo), Lugo (Diócese). Bispo (1847-1857 : Santiago Rodríguez Gil), Rodríguez Gil, Santiago , Bispo de Lugo, and Imprenta de Pujol y Hermano (Lugo)
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Convenio RAG, O bispo de lugo é Santiago Rodríguez Gil
286. Carta pastoral al clero y pueblo del obispado de Lugo
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Pujol y Masiá, Pedro y Hermano, imp, Lugo (Diócese). Bispo (1847-1857: Santiago Rodríguez Gil), Rodriguez Gil, Santiago, Pujol y Masiá, Pedro y Hermano, imp, Lugo (Diócese). Bispo (1847-1857: Santiago Rodríguez Gil), and Rodriguez Gil, Santiago
287. Initial results of magnetic resonance hysterosalpingography diagnostic performance
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Kohan, Andrés Alejandro, primary, Kucharczyk, Mariana Cecilia, additional, Posadas, Natalia T., additional, Napoli, Noelia N., additional, Gil, Santiago Jose, additional, Fuentes, Nora Angélica, additional, García-Mónaco, Ricardo Daniel, additional, and Chacón, Carolina Rosa Beatriz, additional
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- 1970
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288. Procesos comunicativos en la atención odontológica: vivencias de personas Sordas. Medellín, Colombia.
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Díaz Mosquera, Paulina, Carrascal Vega, Angélica, Guevara Angel, Valery, Parra Gil, Santiago, Salazar Durango, Miguel Ángel, Trigos Contreras, Angie Loreny, and Valencia Gallego, Stefania
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DENTAL care , *DEAF people , *MEDICAL personnel , *SIGN language , *RIGHT to health , *COMMUNICATION , *UNIVERSITIES & colleges , *MEDICAL consultation , *DENTISTS - Abstract
Introduction : Deaf individuals in Colombia possess the distinctive trait of communicating with others through Colombian Sign Language (LSC) and encounter communication challenges when accessing health services due to their affiliation with a linguistic and cultural minority. Objectives : To describe the experiences of Deaf individuals in communicative processes during dental care. Methodology: A qualitative study was conducted involving 32 Deaf individuals, both male and female, of legal age, who participated in individual and group interviews. Throughout these interviews, participants shared instances of their experiences in dental consultations. Data were coded, categorized, and relationship maps were developed for analysis. Results were communicated to participants through educational material in sign language. Results : Participants narrate the challenges faced in autonomously accessing health services, as well as their experience of being uninformed during care. They also highlight opportunities for receiving dignified and quality care, necessitating transformations in services, healthcare professionals, and higher education institutions within the context of Deaf culture. Conclusions : Communicative processes in the interaction between dentists and Deaf individuals present an opportunity to better comprehend the Deaf experience in healthcare, question the normalcy in healthcare provision, and recognize the importance of addressing differences. [ABSTRACT FROM AUTHOR]
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- 2023
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289. Study of a sol–gel precursor and its evolution towards ZnO.
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Gómez-Núñez, Alberto, López, Concepción, Alonso-Gil, Santiago, Roura, Pere, and Vilà, Anna
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ZINC oxide , *CHEMICAL precursors , *ZINC acetate , *SOL-gel processes , *SOLVENTS , *X-ray diffraction - Abstract
The processes involved in the assembly of zinc acetate dihydrate {Zn(CH 3 COO) 2 ·2H 2 O} and ethanolamine (H 2 NCH 2 CH 2 OH), with or without 2-methoxyethanol as solvent, have been analysed by infrared spectra, mass spectrometry, nuclear magnetic resonance, powder X-ray diffraction and computational studies. Thermal evolution of the mixtures was characterized by thermoanalytical and structural techniques (thermogravimetry, differential thermal analysis, differential scanning calorimetry, X-ray diffraction and X-Ray photoelectron spectroscopy). Computational studies together with experiments served to thoroughly describe the precursor and its decomposition. The thermal decomposition of the mixture and its transformation into crystalline ZnO take place in a temperature range between 50 and 450 °C through different processes. With solvent, the processes need temperatures 90 °C higher with respect to the mixture without solvent, and ZnO arises at 250 °C. [ABSTRACT FROM AUTHOR]
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- 2015
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290. Oxycodone/naloxone versus tapentadol in real-world chronic non-cancer pain management: an observational and pharmacogenetic study.
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Barrachina, Jordi, Margarit, Cesar, Muriel, Javier, López-Gil, Santiago, López-Gil, Vicente, Vara-González, Amaya, Planelles, Beatriz, Inda, María-del-Mar, Morales, Domingo, and Peiró, Ana M.
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PAIN management , *MEDICAL prescriptions , *CHRONIC pain , *NALOXONE , *OXYCODONE , *CONCOMITANT drugs - Abstract
Tapentadol (TAP) and oxycodone/naloxone (OXN) potentially offer an improved opioid tolerability. However, real-world studies in chronic non-cancer pain (CNCP) remain scarce. Our aim was to compare effectiveness and security in daily pain practice, together with the influence of pharmacogenetic markers. An observational study was developed with ambulatory test cases under TAP (n = 194) or OXN (n = 175) prescription with controls (prescribed with other opioids (control), n = 216) CNCP patients. Pain intensity and relief, quality of life, morphine equivalent daily doses (MEDD), concomitant analgesic drugs, adverse events (AEs), hospital frequentation and genetic variants of OPRM1 (rs1799971, A118G) and COMT (rs4680, G472A) genes, were analysed. Test CNCP cases evidenced a significantly higher pain relief predictable due to pain intensity and quality of life (R2 = 0.3), in front of controls. Here, OXN achieved the greatest pain relief under a 28% higher MEDD, 8–13% higher use of pregabalin and duloxetine, and 23% more prescription change due to pain, compared to TAP. Whilst, TAP yielded a better tolerability due the lower number of 4 [0–6] AEs/patient, in front of OXN. Furthermore, OXN COMT-AA homozygotes evidenced higher rates of erythema and vomiting, especially in females. CNCP real-world patients achieved higher pain relief than other traditional opioids with a better tolerability for TAP. Further research is necessary to clarify the potential influence of COMT and sex on OXN side-effects. [ABSTRACT FROM AUTHOR]
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- 2022
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291. N6-methyladenosine in 5′ UTR does not promote translation initiation.
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Guca, Ewelina, Alarcon, Rodrigo, Palo, Michael Z., Santos, Leonardo, Alonso-Gil, Santiago, Davyt, Marcos, de Lima, Leonardo H.F., Boissier, Fanny, Das, Sarada, Zagrovic, Bojan, Puglisi, Joseph D., Hashem, Yaser, and Ignatova, Zoya
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ADENOSINES , *HOMEOSTASIS , *STACKING interactions , *OXIDATIVE stress , *GENETIC translation , *ARGININE - Abstract
The most abundant N6-methyladenosine (m6A) modification on mRNAs is installed non-stoichiometrically across transcripts, with 5′ untranslated regions (5′ UTRs) being the least conductive. 5′ UTRs are essential for translation initiation, yet the molecular mechanisms orchestrated by m6A remain poorly understood. Here, we combined structural, biochemical, and single-molecule approaches and show that at the most common position, a single m6A does not affect translation yields, the kinetics of translation initiation complex assembly, or start codon recognition both under permissive growth and following exposure to oxidative stress. Cryoelectron microscopy (cryo-EM) structures of the late preinitiation complex reveal that m6A purine ring established stacking interactions with an arginine side chain of the initiation factor eIF2α, although with only a marginal energy contribution, as estimated computationally. These findings provide molecular insights into m6A interactions with the initiation complex and suggest that the subtle stabilization is unlikely to affect the translation dynamics under homeostatic conditions or stress. [Display omitted] • m6A in the close proximity of the start codon does not affect translation yields • Single m6A in the 5′ UTR does not alter initiation complex assembly kinetics • m6A establishes stacking interactions with an arginine side chain of eIF2α • The stacking interactions between m6A and Arg(eIF2α) have marginal energetic contribution Guca et al. use an integrative approach, including functional, structural, single-molecule, and computational approaches, and show that a single m6A in the 5′ UTR does not affect translation dynamics under homeostatic conditions or stress. They observe interactions between m6A with an arginine side chain of eIF2α, although with only a marginal energy contribution. [ABSTRACT FROM AUTHOR]
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- 2024
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292. Trypanosoma cruzi surface mucins are involved in the attachment to the Triatoma infestans rectal ampoule.
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Cámara, María de los Milagros, Balouz, Virginia, Centeno Cameán, Camila, Cori, Carmen R., Kashiwagi, Gustavo A., Gil, Santiago A., Macchiaverna, Natalia Paula, Cardinal, Marta Victoria, Guaimas, Francisco, Lobo, Maite Mabel, de Lederkremer, Rosa M., Gallo-Rodríguez, Carola, and Buscaglia, Carlos A.
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GLYCANS , *MUCINS , *TRYPANOSOMA cruzi , *MEMBRANE glycoproteins , *SCAFFOLD proteins , *BINDING site assay - Abstract
Background: Trypanosoma cruzi, the agent of Chagas disease, is a protozoan parasite transmitted to humans by blood-sucking triatomine vectors. However, and despite its utmost biological and epidemiological relevance, T. cruzi development inside the digestive tract of the insect remains a poorly understood process. Methods/Principle findings: Here we showed that Gp35/50 kDa mucins, the major surface glycoproteins from T. cruzi insect-dwelling forms, are involved in parasite attachment to the internal cuticle of the triatomine rectal ampoule, a critical step leading to its differentiation into mammal-infective forms. Experimental evidence supporting this conclusion could be summarized as follows: i) native and recombinant Gp35/50 kDa mucins directly interacted with hindgut tissues from Triatoma infestans, as assessed by indirect immunofluorescence assays; ii) transgenic epimastigotes over-expressing Gp35/50 kDa mucins on their surface coat exhibited improved attachment rates (~2–3 fold) to such tissues as compared to appropriate transgenic controls and/or wild-type counterparts; and iii) certain chemically synthesized compounds derived from Gp35/50 kDa mucins were able to specifically interfere with epimastigote attachment to the inner lining of T. infestans rectal ampoules in ex vivo binding assays, most likely by competing with or directly blocking insect receptor(s). A solvent-exposed peptide (smugS peptide) from the Gp35/50 kDa mucins protein scaffolds and a branched, Galf-containing trisaccharide (Galfβ1–4[Galpβ1–6]GlcNAcα) from their O-linked glycans were identified as main adhesion determinants for these molecules. Interestingly, exogenous addition of a synthetic Galfβ1–4[Galpβ1–6]GlcNAcα derivative or of oligosaccharides containing this structure impaired the attachment of Dm28c but not of CL Brener epimastigotes to triatomine hindgut tissues; which correlates with the presence of Galf residues on the Gp35/50 kDa mucins’ O-glycans on the former but not the latter parasite clone. Conclusion/Significance: These results provide novel insights into the mechanisms underlying T. cruzi-triatomine interplay, and indicate that inter-strain variations in the O-glycosylation of Gp35/50 kDa mucins may lead to differences in parasite differentiation and hence, in parasite transmissibility to the mammalian host. Most importantly, our findings point to Gp35/50 kDa mucins and/or the Galf biosynthetic pathway, which is absent in mammals and insects, as appealing targets for the development of T. cruzi transmission-blocking strategies. [ABSTRACT FROM AUTHOR]
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- 2019
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293. Sequential Portal Vein Embolization: a Technical Option for Hepatic Metastasis Resection.
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Lama, Carmen, Parada, Carlos, Artacho, Juan R., Contreras, David, and Gil, Santiago
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PORTAL vein surgery , *HEPATECTOMY , *LIVER tumors , *METASTASIS , *THERAPEUTIC embolization , *TREATMENT effectiveness - Abstract
We present the clinical case of a patient who, having been referred for surgery on two-stage hepatectomy, could not have a conventional portal embolization performed as an intermediate step in order to be able to resection the whole of the hepatic illness she was suffering. During right portal embolization (PE), the portography revealed minimal flow in the left portal vein, without thrombosis or stenosis. Given the risk of serious hepatic insufficiency, the embolization procedure was ruled out. Our option was to perform a portal embolization in two stages: initial PE of the right posterior branch, and subsequently, right anterior branch PE. After that, the liver resection could be completed. [ABSTRACT FROM AUTHOR]
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- 2020
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294. Quantum teleportation of spatial images: fundamentals and technological limitations
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Compte Prades, Joel, Universitat Politècnica de Catalunya. Física, Institut de Ciències Fotòniques (ICFO), Fundació Catalunya La Pedrera, Pérez Torres, Juan, and Torres Gil, Santiago
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Quantum teleportation ,Photonics ,Fotònica ,Enginyeria de la telecomunicació::Telecomunicació òptica::Fotònica [Àrees temàtiques de la UPC] ,Quantum optical technologies - Abstract
Quantum teleportation is a crucial resource in future quantum networks. It allows the transfer of quantum information unknown to two parties that share a quantum channel and a classical channel. It was proposed in 1993 [C. H. Bennet et al., PRL 70, 1895 (1992)] and first demonstrated experimentally in 1997 [D. Boschi et al., PRL 80, 1121 (1998); D. Bouwmeester et al., Nature 390, 575 (1997)]. From that time on many experiments have proved the quantum teleportation protocol under different circumstances: with information embedded in photons or/and atoms, in longer and longer distances. For teleporting the large amount of information embedded in spatial images one requires the use of multidimensional quantum teleportation. In general, these schemes are cumber- some to implement experimentally [Xi-LinWang et al., Nature Photonics 518, 516 (2015); Yi-Han Luo et al., PRL 123, 070505 (2019)], because it is difficult to implement Bell state analysers that can faithfully detect many Bell states. However, S. Molotkov proposed in 1998 a scheme to teleport single-photon wave-packets, and therefore spatial images, that overcomes most of the limitations of the standard procedures [S. N. Molotkov, JEPT Let- ters 68, 263 (1998); Physics Letters A 245, 339 (1998)]. Recently this scheme has been demonstrated experimentally [B. Sephton et al., High- dimensional spatial teleportation enabled by nonlinear optics, arXiv:2111.13624v1 [quant- ph] (2021)]. In this project we will analyse with detail the experimental implementation of the scheme to teleport images with current technology and its limitations.
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- 2022
295. Feasibility study of space debris detection by small optical telescopes
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Manresa Ortiz, Samuel, Raddi, Roberto, Torres Gil, Santiago, and Universitat Politècnica de Catalunya. Departament de Física
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Residus espacials ,Optical telescope ,Space debris--Tracking ,Space debris ,Aeronàutica i espai::Astronàutica [Àrees temàtiques de la UPC] - Abstract
Space debris is a currently increasing aerospace problem. Several organizations and space agencies put a great effort in time and resources for their detection and follow up. However, given the overwhelming number of space junk debris and the great variety of sizes, it surpasses the capabilities of any particular project. Small optical telescopes, such as the Joan Or¿o Telescope at the Montsec Astronomical Facilities and JAST80 at the Jalavalambre Observatory may contribute to alleviate this problem. In this thesis, an initial general review of space debris detection is presented, especially focused on the detection and observation with small optical telescopes. Then, with the use of open software, ORDEM 3.1 from NASA, a set of simulations is performed in order to reproduce the observable characteristics of space debris, such as different orbital parameters, debris sizes and configurations. These simulations are adapted to the Joan Or¿o Telescope, at the Parc Observatori de Montsec and the JAST80, at the Observatorio Astronomico de Javalambre, in order to elucidate the possibility of observing such objects. The study is done using two types of coordinate systems for observations: equatorial and altazimuth, both implemented in Montsec and Javalambre. To check the viability of the thesis, our results are compared to those from real studies that have been done with optical telescope, particularly the Zimmerwald telescope for GEO debris, and Mt. Haleakala and Diego Garcia island telescopes for LEO debris. Finally, as main results we can point out that equatorial coordinates system presents the capability of detecting brightest objects, specifically in Montsec. On the other hand, altazimuth coordinate system shows the possibility of detecting faintest objects and in particular in Javalambre observatory. The detectable objects will range from tiny objects (1 cm) to large objects (more than 1 m of diameter).
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- 2022
296. Estudio de síntesis poblacional de la población de enanas blancas de Gaia
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Ferrer i Burjachs, Aina, Universitat Politècnica de Catalunya. Departament de Física, Torres Gil, Santiago, and Rebassa Mansergas, Alberto
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Astrofísica ,Física::Astronomia i astrofísica [Àrees temàtiques de la UPC] ,sistemas binarios ,binary systems ,Nanes blanques ,Astrophysics ,nanas blancas ,white dwarfs - Abstract
We conduct a population synthesis study of the white dwarf population within 100pc from the Sun. Such simulations are based on a detailed Monte Carlo code, which provides synthetic samples of both single and binary stars for different input parameters. Synthetic outcomes are compared with observed data obtained from the recent Gaia mission in its early data release 3. In a first step we compute the outcome of the synthetic sample in the Gaia magnitude system, introduce the photometric and astrometric errors according to Gaia prescriptions and apply the corresponding selection cuts. Then we analyze the general statistical properties, such as the number-counts and percentages of the complete range of sub-populations which contain at least one white dwarf component, i.e. single and merger white dwarfs, white dwarf plus main sequence binaries, and double white dwarfs; in its two modalities, resolved and unresolved systems. The comparison between the observed and the several outcomes of the simulations are mainly based of the fractions of the different sub-samples and their distribution within the Hertzsrpung-Russell diagram. To assist the statistical analysis of observed and synthetic distributions we introduce a generalization of the Kolmogorov-Smirnov test applied to two-dimensional density distributions. Our analysis reveals that any of the models analyzed in this project perfectly agrees with the observed percentages of all the different sub-populations. However, a flat or even a decreasing initial mass ratio distribution seems to be a reasonable first guess, while an increasing relation can be discarded. Further work is needed expanding the number of models and input parameters. Realizamos un estudio de síntesis de población de la población de enanas blancas a menos de 100pcs del sol. Estas simulaciones se basan en un detallado código de Monte Carlo, que proporciona muestras sintéticas de estrellas simples y binarias para diferentes parámetros de entrada. Los resultados sintéticos se comparan con los datos observados obtenidos de la reciente misión de Gaia en su early data release 3. En un primer paso, calculamos el resultado de la muestra sintética al sistema de magnitud de Gaia, introducimos los errores fotométricos y astrométricos según las prescripciones de Gaia y aplicamos los cortes de selección correspondientes. A continuación, analizamos las propiedades estadísticas generales, como los números y porcentajes del rango completo de subpoblaciones que contienen al menos una componente de enana blanca, es decir, enanas blancas simples y de mergers, binarias de enana blanca más secuencia principal y dobles enanas blancas; en sus dos modalidades, sistemas resueltos y no resueltos. La comparación entre los resultados observados y los de las diversas simulaciones se basa principalmente en las fracciones de las diferentes submuestras y su distribución dentro del diagrama de Hertzsrpung-Russell. Para ayudar al análisis estadístico de las distribuciones observadas y sintéticas, introducimos una generalización de la prueba de Kolmogorov-Smirnov aplicada a distribuciones de densidad bidimensionales. Nuestro análisis revela que ninguno de los modelos analizados en este proyecto coincide perfectamente con los porcentajes observados de todas las diferentes subpoblaciones. Sin embargo, una relación de distribución inicial de la masa plana, o incluso una decreciente, parece ser una primera suposición razonable, mientras que se puede descartar una relación creciente. Es necesario continuar trabajando ampliando el número de modelos y parámetros de entrada. Realitzem un estudi de síntesi de població de la població de nanes blanques a menys de 100pc del Sol. Aquestes simulacions es basen en un detallat codi de Monte Carlo, que proporciona mostres sintètiques d'estrelles simples i binàries per a diferents paràmetres d'entrada. Els resultats sintètics es comparen amb les dades observades obtingudes de la recent missió de Gaia en la seu early data release 3. En un primer pas, calculem el resultat de la mostra sintètica al sistema de magnitud de Gaia, introduïm la errors fotomètrics i astromètrics segons les prescripcions de Gaia i apliquem els talls de selecció corresponents. A continuació, analitzem les propietats estadístiques generals, com ara els nombres i percentatges del rang complet de subpoblacions que contenen almenys un component de nana blanca, és a dir, nanes blanques simples i de mergers, binàries de nana blanca més seqüència principal i doble nanes blanques; en les seves dues modalitats, sistemes resolts i no resolts. La comparació entre els resultats observats i els de les diverses simulacions es basa principalment en les fraccions de les diferents submostres i la seva distribució dins del diagrama de Hertzsrpung-Russell. Per ajudar a l'anàlisi estadística de les distribucions observades i sintètiques, introduïm una generalització de la prova de Kolmogorov-Smirnov aplicada a distribucions de densitat bidimensionals. La nostra anàlisi revela que cap dels models analitzats en aquest projecte coincideix perfectament amb els percentatges observats de totes les diferents subpoblacions. No obstant això, una relació de distribució inicial de la massa plana, o fins i tot una decreixent, sembla ser una primera suposició raonable, mentre que es pot descartar una relació creixent. Es necessari continuar treballant ampliant el nombre de models i paràmetres d'entrada.
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- 2021
297. Clonación cuántica variacional en un procesador fotónico cuántico
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Nicolau Orell, Sebastià, Universitat Politècnica de Catalunya. Departament de Física, Sorbonne Université, Kashefi, Elham, and Torres Gil, Santiago
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Quantum optics ,Photonics ,machine learning ,aprendizaje automático ,Fotònica ,computación cuántica ,fotónica ,Enginyeria de la telecomunicació::Telecomunicació òptica::Fotònica [Àrees temàtiques de la UPC] ,quantum computing ,Òptica quàntica - Abstract
The Variational Quantum Cloning algorithm uses machine learning to obtain through optimization a circuit capable of generating approximate clones from unknown input quantum states. We adapt this algorithm to a boson sampling photonic platform formed exclusively by phase-shifters and beam-splitters, which is not universal but it still allows us to achieve quantum advantage. We have been able to obtain results through simulations reaching optimal fidelities for 1 to 2 universal cloning and also 1 to 2 and 1 to 3 phase-covariant cloning. This project demonstrates the capabilities of this type of photonic platforms and it can be used as a reference to adapt other variational algorithms to them. El algoritmo de clonación cuántica variacional hace uso de aprendizaje automático para obtener a través de optimización un circuito capaz de generar clones aproximados desde estados cuánticos de entrada desconocidos. Adaptamos este algoritmo a una plataforma fotónica de muestreo de bosones formada por divisores de haz y cambiadores de fase, la cual no es universal pero permite alcanzar ventaja cuántica. Se han obtenido resultados a través de simulaciones alcanzando fidelidades óptimas para clonación universal 1 a 2 y también para clonación de fase covariante 1 a 2 y 1 a 3. Este proyecto demuestra las capacidades de este tipo de plataformas fotónicas y puede ser utilizado como referencia para adaptar otros algoritmos variacionales en ellas. L'algorisme de clonació quàntica variacional fa servir aprenentatge automàtic per obtenir a través d'optimizació un circuit capaç de generar clons aproximats des d'estats quàntics d'entrada desconeguts. Adaptem aquest algorisme a una plataforma fotònica de mostreig de bosons formada per divisors de feix i canviadors de fase, la qual no és universal però ens permet assolir avantatge quàntic. S'han obtingut resultats a través de simulacions assolint fidelitats òptimes per a clonació universal 1 a 2 i també per a clonació de fase covariant 1 a 2 i 1 a 3. Aquest projecte demostra les capacitats d'aquest tipus de plataformes fotòniques i pot ser utilitzat com a referència per adaptar-hi altres algorismes variacionals.
- Published
- 2021
298. Spectral automated classification in large databases
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Echeverry Valencia, Cristian David, Rebassa Mansergas, Alberto, Torres Gil, Santiago, and Universitat Politècnica de Catalunya. Departament de Física
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Databases ,Artificial intelligence ,Física::Astronomia i astrofísica [Àrees temàtiques de la UPC] ,Statistical astronomy ,Algorismes ,Algorithms ,Spectroscopy - Abstract
Due to the vast amount of data collected every day, there exists a need of modelling Machine Learning algorithms that are able to manipulate and link the raw data with as little human supervision as possible. One of the most popular is the Random Forest, which can be used to solve a great variety of categorization tasks. Particularly, in Astronomy millions of objects are captured by satellites and telescopes, for instance by the Gaia space mission, and the receiving signals are displayed in a spectrum. Random Forest algorithms have been proven to be a versatile and powerful tool in identifying and classifying stellar populations. In the present project, we apply a Random Forest algorithm based on spectroscopic analysis with the aim of efficiently classifying three different populations of stars of particular interest. Our main objective is to study the principle parameters and variables that affect the classification performance of the algorithm, and also to model the Random Forest to categorize observed spectra by current and future missions. We aim to obtain the best results according to the characteristics of each population, while maintaining an efficient and versatile model. To achieve that, we rely on both simulated and observed spectra to train and test the algorithm, and on quantitative metrics to measure its performance. Along this project, we have set the basis of the modelled Random Forest classifier and the preparation of the data, analyzing the theoretical classification with simulated data. We have classified with the Random Forest model a real set of spectroscopic data collected by the Sloan Digital Sky Survey, which revealed a notable agreement between the human-made and the Random Forest classifications, greatly enhanced after the application of different improvements to the algorithm. Finally, we simulated spectra of the expected observed population that will be released by the Gaia space mission, and built a Random Forest model based on it. Several improvements were introduced, but we could eventually achieve a solid model with satisfactory results. With that, we were able to classify two different sets of stellar spectra with different characteristics, maximizing the number of well classified objects while minimizing the amount of false positives.
- Published
- 2021
299. Machine learning classification of the Gaia 3rd data release based on a random forest algorithm
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Lopez Moreno, Sergio, Torres Gil, Santiago, Cantero Mitjans, Carles, and Universitat Politècnica de Catalunya. Departament de Física
- Subjects
Machine Learning ,Gaia Space Mission ,Física::Astronomia i astrofísica [Àrees temàtiques de la UPC] ,Random Forest Algorithm ,Classification ,White dwarf stars ,Stars ,Simulation ,Estels - Abstract
A new Gaia data release, EDR3, has been available since the end of last year containing a complete catalogue of nearly 2 billion stars. This huge wealth of information provided by this magnificent space astronomical mission needs to be analyzed and studied in detail. In particular, we have fixated on a specific type of star, named white dwarf, and we have studied to which population of the Galaxy they belong. This knowledge can help us to understand how our Galaxy was formed and also help to discover large scale Galactic events which are matter of debate. This project is focused on obtaining the most adequate possible classification of the white dwarf population among the three main components of our Galaxy (thin and thick disk and halo) by means of artificial intelligence techniques, and more specifically, machine learning. The algorithm chosen for our purpose has been the random forest algorithm, which, as demonstrated in previous works, has already produced very positive results when applied to the second Gaia data release. We reproduce the results previously obtained for the white dwarf 100 pc Gaia DR2 sample, and extend the analysis to the new EDR3 up to 500 pc. The number of white dwarf finally classified by our algorithm have increased from 10,000 in DR2 up to 80,000 in EDR3. Thus, we have managed to identify nearly 300 halo white dwarf candidates.
- Published
- 2021
300. Unrelated umbilical cord blood transplants in adults: Early recoveryof neutrophils by supportive co-transplantation of a low number of highlypurified peripheral blood CD34+ cells from an HLA-haploidentical donor
- Author
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Fernández, Manuel N., Regidor, Carmen, Cabrera, Rafael, García-Marco, José A., Forés, Rafael, Sanjuán, Isabel, Gayoso, Jorge, Gil, Santiago, Ruíz, Elena, Little, Ann-Margaret, McWhinnie, Alasdair, and Madrigal, Alejandro
- Subjects
- *
NEUTROPENIA , *BLOOD cells - Abstract
Objective, Methods, and Results. To reduce the period of posttransplant neutropenia and related early morbidity and mortality of cord blood (CB) transplants, we assessed the feasibility of co-infusion of a low number of highly purified peripheral blood CD34+ cells from a related haploidentical donor with a CB graft. Between March 1999 and May 2002, 11 patients with high-risk hematologic malignancies were transplanted using this strategy. The seven patients who received a haploidentical peripheral blood graft and a CB graft from a sibling (6) or the father (1) had prompt recovery (9–17 days, median 10) of the absolute neutrophil count (ANC) to greater than 0.5×109/L. Analysis of DNA polymorphisms showed initial predominance of the haploidentical genotype both in granulocytes and in mononuclear cells, and subsequent progressive replacement by cells of CB genotype until final complete CB chimerism was achieved by patients who survived for sufficient periods of time. The four patients who received maternal haploidentical cells had no significant contribution of these to blood leukocytes, although complete CB chimerism was achieved by three of them and two reached engraftment of the CB on days +20 and +36. Morbidity due to early bacterial or fungal infections was remarkably low in patients with prompt ANC recovery.Conclusion. Our data show that co-infusion of a CB unit and a low number of haploidentical CD34+ cells may result in a shortened period of posttransplant neutropenia. This is likely the result of prompt and transient engraftment of the haploidentical hematopoietic stem cells that may provide the patient antimicrobial protection until the later engraftment of the CBhematopoietic stem cells. [Copyright &y& Elsevier]
- Published
- 2003
- Full Text
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