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5,069 results on '"Gopika"'

274. A test of constancy of dark matter halo surface density and radial acceleration relation in relaxed galaxy groups

Author

K, Gopika and Desai, Shantanu

Subjects
Astrophysics - Cosmology and Nongalactic Astrophysics
Abstract

The dark matter halo surface density, given by the product of the dark matter core radius ($r_c$) and core density ($\rho_c$) has been shown to be a constant for a wide range of isolated galaxy systems. Here, we carry out a test of this {\em ansatz} using a sample of 17 relaxed galaxy groups observed using Chandra and XMM-Newton, as an extension of our previous analysis with galaxy clusters. We find that $\rho_c \propto r_c^{-1.35^{+0.16}_{-0.17}}$, with an intrinsic scatter of about 27.3%, which is about 1.5 times larger than that seen for galaxy clusters. Our results thereby indicate that the surface density is discrepant with respect to scale invariance by about 2$\sigma$, and its value is about four times greater than that for galaxies. Therefore, the elevated values of the halo surface density for groups and clusters indicate that the surface density cannot be a universal constant for all dark matter dominated systems. Furthermore, we also implement a test of the radial acceleration relation for this group sample. We find that the residual scatter in the radial acceleration relation is about 0.32 dex and a factor of three larger than that obtained using galaxy clusters. The acceleration scale which we obtain is in-between that seen for galaxies and clusters., Comment: 11 pages, 8 figures. Accepted in Phys. Dark universe

Published
2021
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275. FACT: A Full-body Ad-hoc Collaboration Testbed for Modeling Complex Teamwork

Author

Ajaykumar, Gopika, Mao, Annie, Brown, Jeremy, and Huang, Chien-Ming

Subjects
Computer Science - Robotics
Abstract

Robots are envisioned to work alongside humans in applications ranging from in-home assistance to collaborative manufacturing. Research on human-robot collaboration (HRC) has helped develop various aspects of social intelligence necessary for robots to participate in effective, fluid collaborations with humans. However, HRC research has focused on dyadic, structured, and minimal collaborations between humans and robots that may not fully represent the large scale and emergent nature of more complex, unstructured collaborative activities. Thus, there remains a need for shared testbeds, datasets, and evaluation metrics that researchers can use to better model natural, ad-hoc human collaborative behaviors and develop robot capabilities intended for large scale emergent collaborations. We present one such shared resource - FACT (Full-body Ad-hoc Collaboration Testbed), an openly accessible testbed for researchers to obtain an expansive view of the individual and team-based behaviors involved in complex, co-located teamwork. We detail observations from a preliminary exploration with teams of various sizes and discuss potential research questions that may be investigated using the testbed. Our goal is for FACT to be an initial resource that supports a more holistic investigation of human-robot collaboration., Comment: 5 pages, 3 figures, 2021 ICRA Workshop on Social Intelligence in Humans and Robots

Published
2021

276. A Survey on End-User Robot Programming

Author

Ajaykumar, Gopika, Steele, Maureen, and Huang, Chien-Ming

Subjects
Computer Science - Robotics, Computer Science - Human-Computer Interaction
Abstract

As robots interact with a broader range of end-users, end-user robot programming has helped democratize robot programming by empowering end-users who may not have experience in robot programming to customize robots to meet their individual contextual needs. This article surveys work on end-user robot programming, with a focus on end-user program specification. It describes the primary domains, programming phases, and design choices represented by the end-user robot programming literature. The survey concludes by highlighting open directions for further investigation to enhance and widen the reach of end-user robot programming systems., Comment: 35 pages, 1 figure

Published
2021
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286. Bayesian Network Framework for Human Reliability Analysis in Occupational Health and Safety

Author

Garg, Vipul, Saxena, Vyom, Vinod, Gopika, Chattopadhyay, J., Kant, Vivek, Chaari, Fakher, Series Editor, Gherardini, Francesco, Series Editor, Ivanov, Vitalii, Series Editor, Haddar, Mohamed, Series Editor, Cavas-Martínez, Francisco, Editorial Board Member, di Mare, Francesca, Editorial Board Member, Kwon, Young W., Editorial Board Member, Trojanowska, Justyna, Editorial Board Member, Xu, Jinyang, Editorial Board Member, Senthil Kumar, C., editor, Sujatha, R., editor, Muthukumar, R., editor, Rao, K. Balaji, editor, Prakash, Raghu V., editor, and Varde, Prabhakar V., editor

Published
2023
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287. Radiation Resistant Camera Testing in India—An Imperative Initiative Towards Sustainable Practice and Proactive Waste Management

Author

Ahirwar, A. K., Ramteke, P. K., Gopika, V., Gupta, P. K., Joe Peter, K., Chaari, Fakher, Series Editor, Gherardini, Francesco, Series Editor, Ivanov, Vitalii, Series Editor, Haddar, Mohamed, Series Editor, Cavas-Martínez, Francisco, Editorial Board Member, di Mare, Francesca, Editorial Board Member, Kwon, Young W., Editorial Board Member, Trojanowska, Justyna, Editorial Board Member, Xu, Jinyang, Editorial Board Member, Senthil Kumar, C., editor, Sujatha, R., editor, Muthukumar, R., editor, Rao, K. Balaji, editor, Prakash, Raghu V., editor, and Varde, Prabhakar V., editor

Published
2023
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288. Estimation of System Resilience Through Independent Parameter Transient Profile

Author

Prasad, Mahendra, Gopika, V., Chaari, Fakher, Series Editor, Gherardini, Francesco, Series Editor, Ivanov, Vitalii, Series Editor, Haddar, Mohamed, Series Editor, Cavas-Martínez, Francisco, Editorial Board Member, di Mare, Francesca, Editorial Board Member, Kwon, Young W., Editorial Board Member, Trojanowska, Justyna, Editorial Board Member, Xu, Jinyang, Editorial Board Member, Senthil Kumar, C., editor, Sujatha, R., editor, Muthukumar, R., editor, Rao, K. Balaji, editor, Prakash, Raghu V., editor, and Varde, Prabhakar V., editor

Published
2023
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289. Servqual Analysis of Customer Experience on Day-Care Facilities in Global Centre Institute, Sharjah

Author

Gopalakrishnan, Gopika Krishna, Ravindran, D., Hamdan, Allam, Editorial Board Member, Al Madhoun, Wesam, Editorial Board Member, Alareeni, Bahaaeddin, Editor-in-Chief, Baalousha, Mohammed, Editorial Board Member, Elgedawy, Islam, Editorial Board Member, Hussainey, Khaled, Editorial Board Member, Eleyan, Derar, Editorial Board Member, Hamdan, Reem, Editorial Board Member, Salem, Mohammed, Editorial Board Member, Jallouli, Rim, Editorial Board Member, Assaidi, Abdelouahid, Editorial Board Member, Nawi, Noorshella Binti Che, Editorial Board Member, AL-Kayid, Kholoud, Editorial Board Member, Wolf, Martin, Editorial Board Member, El Khoury, Rim, Editorial Board Member, Aloysius Edward, J., editor, Jaheer Mukthar, K. P., editor, Asis, Edwin Ramirez, editor, and Sivasubramanian, K., editor

Published
2023
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291. SMOTE Variants for Data Balancing in Intrusion Detection System Using Machine Learning

Author

Sams Aafiya Banu, S., Gopika, B., Esakki Rajan, E., Ramkumar, M. P., Mahalakshmi, M., Emil Selvan, G. S. R., Angrisani, Leopoldo, Series Editor, Arteaga, Marco, Series Editor, Panigrahi, Bijaya Ketan, Series Editor, Chakraborty, Samarjit, Series Editor, Chen, Jiming, Series Editor, Chen, Shanben, Series Editor, Chen, Tan Kay, Series Editor, Dillmann, Rüdiger, Series Editor, Duan, Haibin, Series Editor, Ferrari, Gianluigi, Series Editor, Ferre, Manuel, Series Editor, Hirche, Sandra, Series Editor, Jabbari, Faryar, Series Editor, Jia, Limin, Series Editor, Kacprzyk, Janusz, Series Editor, Khamis, Alaa, Series Editor, Kroeger, Torsten, Series Editor, Li, Yong, Series Editor, Liang, Qilian, Series Editor, Martín, Ferran, Series Editor, Ming, Tan Cher, Series Editor, Minker, Wolfgang, Series Editor, Misra, Pradeep, Series Editor, Möller, Sebastian, Series Editor, Mukhopadhyay, Subhas, Series Editor, Ning, Cun-Zheng, Series Editor, Nishida, Toyoaki, Series Editor, Oneto, Luca, Series Editor, Pascucci, Federica, Series Editor, Qin, Yong, Series Editor, Seng, Gan Woon, Series Editor, Speidel, Joachim, Series Editor, Veiga, Germano, Series Editor, Wu, Haitao, Series Editor, Zamboni, Walter, Series Editor, Zhang, Junjie James, Series Editor, Singh, Pradeep, editor, Singh, Deepak, editor, Tiwari, Vivek, editor, and Misra, Sanjay, editor

Published
2023
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293. Hybrid Binary Whale Optimization Algorithm for Feature Selection Optimization Problem

Author

Ramya, V., Kumar, E. Vinay, Gopika, G. S., Manoj, G., Kacprzyk, Janusz, Series Editor, Gomide, Fernando, Advisory Editor, Kaynak, Okyay, Advisory Editor, Liu, Derong, Advisory Editor, Pedrycz, Witold, Advisory Editor, Polycarpou, Marios M., Advisory Editor, Rudas, Imre J., Advisory Editor, Wang, Jun, Advisory Editor, Saini, H. S., editor, Sayal, Rishi, editor, Govardhan, A., editor, and Buyya, Rajkumar, editor

Published
2023
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294. Computational Aspects of Double Dominating Sequences in Graphs

Author

Sharma, Gopika, Pandey, Arti, Goos, Gerhard, Founding Editor, Hartmanis, Juris, Founding Editor, Bertino, Elisa, Editorial Board Member, Gao, Wen, Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Yung, Moti, Editorial Board Member, Bagchi, Amitabha, editor, and Muthu, Rahul, editor

Published
2023
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295. Comparison of Dynamic Passenger Car Values Estimated at Signalised Intersections Under Heterogeneous Traffic Conditions

Author

Salini, P. N., Kini, B. Anish, Mohan, Gopika, di Prisco, Marco, Series Editor, Chen, Sheng-Hong, Series Editor, Vayas, Ioannis, Series Editor, Kumar Shukla, Sanjay, Series Editor, Sharma, Anuj, Series Editor, Kumar, Nagesh, Series Editor, Wang, Chien Ming, Series Editor, Anjaneyulu, M. V. L. R., editor, Harikrishna, M., editor, Arkatkar, Shriniwas S., editor, and Veeraragavan, A., editor

Published
2023
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296. Study of Document Clustering Algorithms Applied on Covid Data

Author

Suresh, Sweety, Krishna, Gopika, Thushara, M. G., Kacprzyk, Janusz, Series Editor, Pal, Nikhil R., Advisory Editor, Bello Perez, Rafael, Advisory Editor, Corchado, Emilio S., Advisory Editor, Hagras, Hani, Advisory Editor, Kóczy, László T., Advisory Editor, Kreinovich, Vladik, Advisory Editor, Lin, Chin-Teng, Advisory Editor, Lu, Jie, Advisory Editor, Melin, Patricia, Advisory Editor, Nedjah, Nadia, Advisory Editor, Nguyen, Ngoc Thanh, Advisory Editor, Wang, Jun, Advisory Editor, Dutta, Paramartha, editor, Bhattacharya, Abhishek, editor, Dutta, Soumi, editor, and Lai, Wen-Cheng, editor

Published
2023
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297. Mutations and variants of ONECUT1 in diabetes

Author

Philippi, Anne, Heller, Sandra, Costa, Ivan G, Senée, Valérie, Breunig, Markus, Li, Zhijian, Kwon, Gino, Russell, Ronan, Illing, Anett, Lin, Qiong, Hohwieler, Meike, Degavre, Anne, Zalloua, Pierre, Liebau, Stefan, Schuster, Michael, Krumm, Johannes, Zhang, Xi, Geusz, Ryan, Benthuysen, Jacqueline R, Wang, Allen, Chiou, Joshua, Gaulton, Kyle, Neubauer, Heike, Simon, Eric, Klein, Thomas, Wagner, Martin, Nair, Gopika, Besse, Céline, Dandine-Roulland, Claire, Olaso, Robert, Deleuze, Jean-François, Kuster, Bernhard, Hebrok, Matthias, Seufferlein, Thomas, Sander, Maike, Boehm, Bernhard O, Oswald, Franz, Nicolino, Marc, Julier, Cécile, and Kleger, Alexander

Subjects
Stem Cell Research, Autoimmune Disease, Diabetes, Clinical Research, Genetics, 2.1 Biological and endogenous factors, Aetiology, Metabolic and endocrine, Cell Differentiation, Congenital Abnormalities, Diabetes Mellitus, Type 2, Fetal Growth Retardation, Gallbladder, Hepatocyte Nuclear Factor 6, Homeobox Protein Nkx-2.2, Homeodomain Proteins, Humans, Infant, Infant, Newborn, Male, Multifactorial Inheritance, Organogenesis, Pancreas, Pancreatic Diseases, Pluripotent Stem Cells, Transcription, Genetic, Medical and Health Sciences, Immunology
Abstract

Genes involved in distinct diabetes types suggest shared disease mechanisms. Here we show that One Cut Homeobox 1 (ONECUT1) mutations cause monogenic recessive syndromic diabetes in two unrelated patients, characterized by intrauterine growth retardation, pancreas hypoplasia and gallbladder agenesis/hypoplasia, and early-onset diabetes in heterozygous relatives. Heterozygous carriers of rare coding variants of ONECUT1 define a distinctive subgroup of diabetic patients with early-onset, nonautoimmune diabetes, who respond well to diabetes treatment. In addition, common regulatory ONECUT1 variants are associated with multifactorial type 2 diabetes. Directed differentiation of human pluripotent stem cells revealed that loss of ONECUT1 impairs pancreatic progenitor formation and a subsequent endocrine program. Loss of ONECUT1 altered transcription factor binding and enhancer activity and NKX2.2/NKX6.1 expression in pancreatic progenitor cells. Collectively, we demonstrate that ONECUT1 controls a transcriptional and epigenetic machinery regulating endocrine development, involved in a spectrum of diabetes, encompassing monogenic (recessive and dominant) as well as multifactorial inheritance. Our findings highlight the broad contribution of ONECUT1 in diabetes pathogenesis, marking an important step toward precision diabetes medicine.

Published
2021

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